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Ethnobotanical Study of Mosquito Repellent Plants Used in Seweyna District, Bale Zone, Southeast, Ethiopia Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-3-15 Asefash Shibeshi, Ayalew Sebsibe, Alemtshay Teka, Esayas Aklilu
Malaria control efforts through vector control strategies are hindered by the development of insecticide resistance by major malaria vectors in many malaria-endemic areas, which necessitate the need for alternative control measures. The aim of this study was to document plants traditionally used as mosquito repellents in Seweyna district, southeastern Ethiopia. The ethnobotanical data were collected
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Effects of Combining Music Therapy, Light Therapy, and Chromotherapy in the Treatment of Chronic Pain Patients: A Pilot Study Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-3-6 Alcira Suarez, Yannick Delgado, Alain Servais, Nicolas Verardi, Delphine Durand, Severine Litaneur, Vincent Wyart, Julien Nizard, Jean-Paul Nguyen
Background. It is currently considered that around 30% of chronic pain patients are totally refractory to medical treatment. Among patients who remain responsive to medical treatment, it is estimated that between 20% and 50% are likely to discontinue treatment due to severe side effects. Given these therapeutic difficulties, a significant number of patients turn to complementary therapies. Objective
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Effectiveness of Mindfulness-Based Stress Reduction on Mental Health and Psychological Quality of Life among University Students: A GRADE-Assessed Systematic Review Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-2-20 Yuanqing Pan, Fusen Li, Haiqian Liang, Xiping Shen, Zhitong Bing, Liang Cheng, Yi Dong
Background. Psychological distress is a progressive health problem that has been linked to decreased quality of life among university students. This meta-analysis reviews existing randomized controlled trials (RCTs) that have examined the effects of mindfulness-based stress reduction (MBSR) on the relief of psychosomatic stress-related outcomes and quality of life among university students. Methods
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The Meaning of Plants’ Names: A New Discovering Approach to Its Medicinal and/or Toxic Properties Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-2-19 Letícia dos Santos Dantas Lima, Luiz Felipe Domingues Passero, Alexandre Indriunas, Ingrid de Souza Santos, Luíza Francisco Uchôa Coqueiro, Kayo Alexandre Souza da Cruz, Adriana Batista de Almeida, José Carlos Fernandes Galduróz, Eliana Rodrigues
Some of the vernacular or scientific names are related to possible medicinal and/or toxic properties that can reveal the presence of potential bioactive agents, contributing to the discovery of new drugs and/or knowledge of the risks associated with their use. This study sought to list the scientific and vernacular names of plants whose lexicons are related to those possible properties of plants and
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Antiplatelet and Antithrombotic Activities of Lespedeza cuneata via Pharmacological Inhibition of Integrin αIIbβ3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-2-9 Abdul Wahab Akram, Evelyn Saba, Man Hee Rhee
Cardiovascular diseases (CVDs) have been the major cause of mortality all around the globe. Lespedeza cuneata abbreviated as L. cuneata with the authority name of Dumont de Courset (G. Don) is a perennial flowering plant commonly grown in Asian countries such as Korea, Japan, China, and Taiwan. We aimed to investigate the L. cuneata extract’s antiplatelet and antithrombotic properties as GC-MS analysis
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An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-2-8 Mohammad Amin Rajizadeh, Hamid Najafipour, Mohammad Abbas Bejeshk
Background. Asthma is a common disease with rising prevalence worldwide, especially in industrialized countries. Current asthma therapy with traditional medicines lacks satisfactory success, hence the patients’ search for alternative and complementary treatments for their diseases. Researchers have conducted many studies on plants with antiallergic and antiasthmatic effects in recent decades. Many
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Antidepressant-Like Activity and Molecular Docking Analysis of a Sesquiterpene Lactone Isolated from the Root Bark of Ximenia americana (L.) Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-2-3 Tekeste Abebe, Ariaya Hymete, Mirutse Giday, Daniel Bisrat
Depression, a global cause of disability and premature death, is often treated by traditional healers in Africa using medicinal herbs such as Ximenia americana (L.). With recent pharmacological studies showing the potential antidepressant properties of X. americana extract, this study aimed to evaluate the antidepressant-like effects of the compound(s) isolated from X. americana extract using the forced
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Biofilm-Inhibitory Activity of Wild Mushroom Extracts against Pathogenic Bacteria Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-29 Gebreselema Gebreyohannes, Desta Berhe Sbhatu, Andrew Kimang’a Nyerere, Abrha Gebreselema Gebrehiwot
Objective. This study aims to investigate the bacterial biofilm-inhibitory effect of mushroom extracts. Methods. Mushrooms were collected from Arabuko-Sokoke and Kakamega forests and identified using morphological and molecular approaches. Auricularia auricula-judae, Microporus xanthopus, Termitomyces umkowaani, Trametes elegans, and Trametes versicolor were extracted by chloroform, 70% ethanol, and
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Green Tea Leaves and Rosemary Extracts Selectively Induce Cell Death in Triple-Negative Breast Cancer Cells and Cancer Stem Cells and Enhance the Efficacy of Common Chemotherapeutics Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-25 Chris Raad, Abby Raad, Siyaram Pandey
While incredible medical advancements in chemotherapeutics development for cancer treatment have been made, the majority of these are not selective in their mechanism of action, leading to adverse effects. Given the systemic toxicity associated with these therapies, they are not well suited for long-term use. Natural health products, or NHPs, may provide a way to selectively target the oxidative and
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Development of the Short-Form Yin Deficiency Scale Using Three Item Reduction Approaches Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-19 Young-Jae Park, Ji-Myung Ok
Background. Yin deficiency (YD) is a pathological condition characterized by emaciation, afternoon fever, dry mouth, and night sweats. The incidence of YD is 23.3%. A 27-item Yin Deficiency Scale (YDS) was developed to estimate the clinical severity of YD. This study aimed to develop three short-form YDS versions to reduce the burden of response time, using three item-reduction approaches: Rasch, equidiscriminatory
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Effect of Dill (Anethum graveolens) Oil on Pruritus and Quality of Life of Hemodialysis Patients: A Randomized Double-Blind Three-Arm Controlled Trial Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-16 Zeinab Shaki, Farzaneh Ghaffari, Fatemeh Alijaniha, Mohammad Kamalinejad, Anoshiravan Kazemnejad, Babak Daneshfard, Mohsen Naseri, Mohammad Reza Heidari
Introduction. Anethum graveolens (AG), commonly known as dill, is a plant from the Apiaceae family that has been traditionally used as a skin softener and purifying agent in Persian medicine. In a previous study conducted on male rats, dill was found to have anti-inflammatory effects. The current study aimed to examine the efficacy of topical application of Anethum graveolens oil on pruritus severity
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Health Risk Assessment of Metals in Antidiabetic Herbal Preparations: A Safety Screening Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-12 Nazmul Islam, Rausan Zamir, Md. Omar Faruque
The present study evaluates the human health risk of metals in locally consumed herbal preparations used to treat diabetes. Atomic absorption spectroscopy (AAS) was used after microwave-assisted digestion to mineralize the samples. Toxic metal assessment was done by adopting mathematical modeling for carcinogenic and noncarcinogenic risks in the exposed population and comparing the raw results with
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Anti-Inflammatory Effects of Clematis terniflora Leaf on Lipopolysaccharide-Induced Acute Lung Injury Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-9 Ji-Yeong Park, Min-Jong Kim, Young-Ae Choi, Yeon-Yong Kim, Soyoung Lee, Jae-Min Chung, Sang-Yong Kim, Gil-Saeng Jeong, Sang-Hyun Kim
For centuries, natural products are regarded as vital medicines for human survival. Clematis terniflora var. mandshurica (Rupr.) Ohwi is an ingredient of the herbal medicine, Wei Ling Xian, which has been used in Chinese medicine to alleviate pain, fever, and inflammation. In particular, C. terniflora leaves have been used to cure various inflammatory diseases, including tonsillitis, cholelithiasis
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In Silico and In Vitro Studies of Antibacterial Activity of Cow Urine Distillate (CUD) Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-8 LokRaj Pant, Shankar Thapa, Bibek Dahal, Ravindra Khadka, Mahalakshmi Suresha Biradar
Cow urine distillate (CUD) is a traditional Indian medicine used to treat various diseases, including bacterial infections. However, there is limited evidence to support its use as a medicine, and its safety and efficacy have not been thoroughly studied. In this study, we evaluated the antibacterial activity of CUD against five bacterial strains using in vitro and in silico approaches. In vitro experiments
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Phytochemistry Profile, Antimicrobial and Antitumor Potential of the Methanolic Extract of Tabernaemontana catharinensis A DC and Eragrostis plana NEES Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2024-1-3 Emanoeli da Rosa, Cheila Denise Ottonelli Stopiglia, Michel Mansur Machado, Augusto Cezar Dotta Filho, Ursula Paula Reno Soci, Andreas Sebastian Loureiro Mendez, Tiago Fernandes, Edilamar Menezes de Oliveira, Cleci Menezes Moreira
Natural compounds that have the potential to act as antimicrobials and antitumors are a constant search in the field of pharmacotherapy. Eragrostis plana NEES (Poaceae) is a grass with high allelopathic potential. Allelopathy is associated with compounds generated in the primary and secondary metabolism of the plant, which act to protect it from phytopathogens. Tabernaemontana catharinensis A DC (Apocynaceae)
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In Vitro Cytotoxicity of Reproductive Stage Withania somnifera Leaf and Stem on HepG2 Cell Line Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-26 Lali Lingfa, Aravinda Tirumala, Srinivas Ankanagari
Background. The ayurvedic plant Withania somnifera, a member of the Solanaceae family, has been used as a remedy for diverse health problems, including cancer. Objectives. The objective of this investigation was to conduct a comparative analysis of the in vitro cytotoxic properties of methanolic extracts derived from the leaf, stem, and root of W. somnifera on HepG2 and L929 cell lines. Methods. Methanolic
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Antimalarial Properties of Sida cordifolia L. Leaf Extract in Mice: Survivability Depends Less on Parasitaemia Suppression Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-23 Samuel Ansong, Desmond Nkrumah, Reinhard Isaac Nketia, Samuel Oppong Bekoe, Abena Amponsaa Brobbey, Evelyn Asante-Kwatia, Gustav Komlaga
Sida cordifolia has been used to treat malaria in Ghana albeit without scientific evidence of antimalarial activity and safety. This work aimed to assess the antimalarial properties and acute toxicity of the aqueous leaf extract of S. cordifolia in murine models. Aqueous extract of the plant was analysed for both suppressive and curative antimalarial properties in chloroquine-sensitive ANKA strains
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Cardioprotective Effects of Solidago microglossa DC. in Nicotine-Treated Hypertensive Rats Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-22 Katiana Simões Lopes, Aline Aparecida Macedo Marques, Karyne Garcia Tafarelo Moreno, Ariany Carvalho dos Santos, Roosevelt Isaías Carvalho Souza, Emerson Luiz Botelho Lourenço, Rodrigo Juliano Oliveira, Roberto da Silva Gomes, Francislaine Aparecida dos Reis Lívero, Arquimedes Gasparotto Junior
Solidago microglossa DC. (Asteraceae), “arnica brasileira,” is a Brazilian species popularly used to treat hypertension or renal ailments. This study investigated the cardioprotective effects of standardized S. microglossa extract (EESM) in nicotine-treated spontaneously hypertensive rats (SHRs). Moreover, the molecular mechanisms involved in the cardiovascular effects were also investigated. The acute
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Network Pharmacology and Molecular Docking Explore the Mechanism of Mubiezi-Yinyanghuo Herb Pair in the Treatment of Rheumatoid Arthritis Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-8 Fuxue Meng, Xiaomai Tao, Longkuan Li, Wei Jia, Xin Yang, Yuchen Yang
Objective. Our previous studies have shown that the Mubiezi-Yinyanghuo (MBZ-YYH) herb pair inhibits rheumatoid arthritis (RA) cell proliferation and glycolysis, promising results with an obscure mechanism of action. Methods. Therefore, it is necessary to explore the main components of MBZ-YYH and unravel the potential mechanism in RA based on network pharmacology and molecular docking methods. Components
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Comparative Study on the Biochemical Profile and Antioxidant Activity of Picrorhiza kurrooa Rolye ex Benth. Obtained from Uttarakhand Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-7 Anshika Pokhriyal, Soban Prakash, Babita Patni
Picrorhiza kurrooa Royle ex Benth. is one of the well-established herbal plants with an exceptional therapeutic potential. It belongs to the Scrophulariaceae family and is commonly called as kutki. The drug obtained from the plant is a bitter tonic due to the presence of kutkin in it. Over 61 secondary metabolites from the plants have been identified, including iridoid glycosides, flavonoids, cucurbitacins
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Parrotia persica as a Potential Source of Bioactive Phenolic Compounds: Optimization of Extraction Parameters and Biological Activity Assay Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-6 Mohsen Farhadpour, Niksa Yavari, Vahideh Mahdavi, Fazileh Esmaeili, Reza Zadali
Parrotia persica is one of the endemic plants in Iran and belongs to the Hamamelidaceae family. A wide range of biological activities of this plant have been attributed to several phenolic compounds. In this study, the phenolic bioactive compounds extraction from P. persica leaves was performed using conventional and ultrasonic-assisted extraction (UAE) techniques through the response surface methodology
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Ethnobotanical Study on Medicinal Plants Used by the Local Communities of Ameya District, Oromia Regional State, Ethiopia Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-1 Temesgen Tadesse, Alemtshay Teka
In the present study, the diversity of medicinal plants and associated traditional medicinal knowledge of the rural community in the Ameya district in Ethiopia was assessed and documented. A survey was conducted through semistructured interviews, guided field walks, focus group discussions, and field observations. The snowball and purposeful sampling techniques were employed to select general and knowledgeable
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Antifungal Activity of Bulgarian Rose Damascena Oil against Vaginitis-Causing Opportunistic Fungi Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-12-1 Yejin Lee, Eunhye Park, Bohee Jang, Jisun Hwang, Jinmin Lee, Eok-Soo Oh
Since Bulgarian rose damascena oil is known for its anti-inflammatory, antioxidant, and antimicrobial properties, we investigated its antifungal activity against the species of Candida, which are among the most common opportunistic fungal pathogens. Our disk-diffusion assay revealed that Bulgarian rose damascena oil effectively inhibited the growth of Candida albicans along with various bacteria. The
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Red Ginseng Is a Therapeutic Candidate for Chronic Doxorubicin-Induced Cardiomyopathy in Mice Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-30 Naoki Yoshikawa, Naoto Hirata, Yuichiro Kurone, Shin Ohta, Sadahiko Shimoeda
Doxorubicin-induced cardiomyopathy (DICM) is associated with a poor prognosis, and effective therapeutic drug candidates have yet to be identified. Furthermore, whether basic animal models reflect the clinical pathogenesis of DICM should be carefully examined. Although the exact mechanisms underlying the development of DICM are complex and remain unclear, oxidative stress is strongly implicated as
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Review of Medicinal Plants Traditionally Used to Treat Diarrhea by the People in the Amhara Region of Ethiopia Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-25 Destaw Damtie
Background. Diarrheal illness is the second-most common cause of death in under-five children. Worldwide, it results in about 1.7 billion illnesses and 525,000 deaths among under-five children annually. It is the leading cause of malnutrition among under-five children. Different people use medicinal plants to treat diarrhea. The present study aimed to review the medicinal plants used to treat diarrhea
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Evaluation of the Use, Reasons, and Satisfaction with the Complementary Medicine among Patients Living with a Permanent Ostomy Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-21 Leyla Ahmadi lari, Mahlagha Dehghan, Mohammad Ali Zakeri, Parvin Mangolian shahrbabaki
Patients living with a permanent ostomy encounter many physical, psychological, and social challenges due to the loss of function of a part of their body. Today, as the use of alternative therapies increases, some of these patients are seeking complementary medicine to relieve the symptoms and complications of their disease. Therefore, the present study aimed to determine the use of, reasons for, and
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Antisickling and Antihemolytic Mechanism of Spirulina platensis (Oscillatoriaceae): A Nutraceutical Commonly Used in Cameroon Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-10 Apollinaire Teguem Tchoulegheu, Prudence Josela Nya Nkwikeu, Natacha Lena Yembeau, Arnaud Cyrille Choupo, Celestin Nkenmeni Djamnou, Alfloditte Flore Feudjio, Bernard Chetcha Chemegni, Prosper Cabral Biapa Nya, Constant Anatole Pieme
Sickle cell anaemia (SCA) is a widespread genetic disease in Africa, associated with chronic hemolytic anaemia and vaso-occlusive and infectious complications. The most commonly used means of management and treatment such as blood transfusions and allografting are expensive and predispose patients to the risk of infections. This research study aimed at evaluating the antisickling and antihemolytic
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Bridging the Gap: Exploring the Preclinical Potential of Pereskia grandifolia in Metabolic-Associated Fatty Liver Disease Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-9 Edilson Rodrigues Albuquerque, Gustavo Ratti da Silva, Fernanda de Abreu Braga, Ester Pelegrini Silva, Karina Sposito Negrini, Julia Amanda Rodrigues Fracasso, Lucas Pires Guarnier, Ezilda Jacomassi, João Tadeu Ribeiro-Paes, Roberto da Silva Gomes, Arquimedes Gasparotto Junior, Francislaine Aparecida dos Reis Lívero
Metabolic-associated fatty liver disease (MAFLD) is a complex condition characterized by steatosis and metabolic disturbances. Risk factors such as diabetes, cigarette smoking, and dyslipidaemia contribute to its development and progression. Effective and safe therapies for MAFLD are urgently needed. Pereskia grandifolia has shown potential as an alternative treatment, but its effectiveness against
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Metabolomics of Personalized Body Elements in Thai Traditional Medicine Response to Herbal Medicine for Body Elements Balancing in Healthy Volunteers Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-4 Manmas Vannabhum, Suthatip Mahajaroensiri, Saracha Pattanapholkornsakul, Athippat Tantiwongsekunakorn, Thapthep Thippayacharoentam, Pinpat Tripatara, Pravit Akarasereenont
Background. In Thai traditional medicine (TTM), the dominant body element called “Dhat Chao Ruean” (DCR) is an integral part in the diagnostic process of Thai traditional medicine. TTM practitioners usually use Thai herbal Benjakul formula (BKF) for adjusting and balancing the body elements. However, the effects of BKF on metabolism and individual response to it have not been studied yet. Methods.
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Acupuncture Combined with Voice Training Improved Voice Function in Patients with Primary Muscular Tension Dysphonia (MTD): A Randomized, Three-Armed, Open-Label Clinical Trial Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-3 Fang-Qi Liang, Yu Shi, Lei Dong, Yan Xie, Xiao-Cen Wang, Xin-Ning He, Rong Zhang, Ting Liu, Li Zhou
Objective. This randomized controlled trial aimed to evaluate the clinical efficacy of acupuncture combined with voice training for treating patients with primary muscular tension dysphonia (MTD) (Qi stagnation and blood stasis type in traditional Chinese medicine). Methods. A total of 108 patients with primary MTD (Qi stagnation and blood stasis type) were recruited in this study. The participants
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Retracted: Prevention and Treatment of Cardiovascular Diseases with Plant Phytochemicals: A Review. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-11-01 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/5741198.].
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A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs) Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-31 Gaber El-Saber Batiha, Halimat Yusuf Lukman, Hazem M. Shaheen, Lamiaa Wasef, Amin A. Hafiz, Carlos Adam Conte-Junior, Ammar Al-Farga, Moses V. M. Chamba, Bashir Lawal
Viola L. is the largest genus of the Violaceae family with more than 500 species across the globe. The present extensive literature survey revealed Viola species to be a group of important nutritional and medicinal plants used for the ethnomedicinal treatment of noncommunicable diseases (NCDs) such as diabetes, asthma, lung diseases, and fatigue. Many plant species of this genus have also received
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Protective Effect of Alkaline Mineral Water on Calcium Oxalate-Induced Kidney Injury in Mice Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-25 Lei Liu, Chen Lin, Xiu Li, Yulan Cheng, Rui Wang, Chao Luo, Xinyuan Zhao, Zhitao Jiang
Background. Kidney stone disease induces chronic renal insufficiency by crystal-induced renal tubular epithelial cell injury. It has been reported that the prevalence of kidney stone disease is increasing, accompanied by the high recurrence rate. Alkaline mineral water has been reported to possess beneficial effects to attenuate inflammation. Here, we explored the potential protective effects and underlying
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Shoseiryuto Promotes the Formation of a Tight-Junction Barrier in Cultured Human Bronchial Epithelial Cells Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-21 Jingya Lu, Ailing Hu, Takuji Yamaguchi, Masahiro Tabuchi, Yasushi Ikarashi, Hiroyuki Kobayashi
Shoseiryuto (SST) (Xiao-Qing-Long-Tang in Chinese) is an effective treatment for respiratory diseases, such as bronchial asthma and allergic rhinitis, but its effects on the bronchial tight-junction (TJ) barrier have not been clarified. This study aimed to evaluate the effect of SST on TJ-barrier function in human bronchial epithelial (16HBE) cells. The 16HBE cells were cultured in a culture medium
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Wild Mushrooms: Potential Natural Sources of Antioxidant and Anti-Quorum Sensing Bioactive Compounds for Medical Applications Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-19 Gebreselema Gebreyohannes, Desta Berhe Sbhatu, Andrew Nyerere, Christine Bii, Abrha Gebreselema Gebrehiwot
Objective. This study was aimed at determining the antioxidant, anti-quorum sensing, and in vitro cytotoxic activities of five wild mushroom extracts. Methods. Wild mushrooms of Auricularia auricula-judae, Termitomyces umkowaani, Trametes elegans, Trametes versicolor, and Microporus xanthopus were collected from Arabuko-Sokoke and Kakamega National Forests, in Kenya. Specimens were identified and extracted
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Ethnobotanical Study of Medicinal Plants Used against Human Diseases in Zuway Dugda District, Ethiopia Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Moa Megersa, Tesfaye Nedi, Shiferaw Belachew
Introduction. In Ethiopia, traditional medicine has significantly contributed to the treatment of public health conditions. However, when contrasted with the ethnic diversity of Ethiopians, the number of medicinal plants that have been documented remains limited. As a result, the study aimed to record the medicinal plants used in the Zuway Dugda district communities. Methodology. An ethnobotanical
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Optimizing the Fermentation Conditions of Cudrania tricuspidata Fruit Using Bacillus amyloliquefaciens for Anti-Inflammatory Activity and GC-MS-Based Volatile Component Characteristics Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Si Young Ha, Ji Young Jung, Hyeon Cheol Kim, Jae-Kyung Yang
The aim of this study is to optimize the performance conditions used for maximum anti-inflammatory activity and to clarify in vitroanti-inflammatory properties of fermented C. tricuspidata fruit. Based on the single-factor experiment and Box–Behnken design, the optimized fermentation conditions of C. tricuspidata fruit for maximum anti-inflammatory activity were 3.8 d fermentation period, 8.4% (v/w)
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Retracted: A Smart Solution for Cancer Patient Monitoring Based on Internet of Medical Things Using Machine Learning Approach. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/2056807.].
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Retracted: Clinical Data and Biocalculation Methods of GABRD Determine the Clinical Characteristics and Immune Relevance of Colorectal Cancer. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/6198448.].
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Retracted: Analysis of Relevant Factors Affecting the Pregnancy Rate of Frozen-Thawed Embryo Transfer Cycle. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/2842278.].
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Retracted: Exploration of Potential Biomarkers and Immune Landscape for Hepatoblastoma: Evidence from Machine Learning Algorithm. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-18 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/2417134.].
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Deciphering the Molecular Mechanism of Escin against Neuropathic Pain: A Network Pharmacology Study Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-16 Xi Li, Yating Wu, Haoyan Wang, Zaiqi Li, Xian Ding, Chongyang Dou, Lin Hu, Guizhi Du, Guihua Wei
Background. Escin is the main active component in Aesculus hippocastanum. It has been demonstrated that escin has anti-inflammatory properties. This study combined the methods of network pharmacology, molecular docking, and molecular dynamics to explore the molecular mechanism of escin against neuropathic pain (NP). Methods. The Swiss Target Prediction and the Pharm Mapper database were employed for
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Extracts of Selected South African Medicinal Plants Mitigate Virulence Factors in Multidrug-Resistant Strains of Klebsiella pneumoniae Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-14 Idowu J. Adeosun, Itumeleng T. Baloyi, Sekelwa Cosa
The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae remains a global health threat due to its alarming rates of becoming resistant to antibiotics. Therefore, identifying plant-based treatment options to target this pathogen’s virulence factors is a priority. This study examined the antivirulence activities of twelve plant extracts obtained from three South African medicinal plants (Lippia
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Antioxidant Potential of Ethiopian Medicinal Plants and Their Phytochemicals: A Review of Pharmacological Evaluation Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-12 Gashaw Nigussie, Abolghasem Siyadatpanah, Roghayeh Norouzi, Eyob Debebe, Mekdelawit Alemayehu, Aman Dekebo
Background. Free radicals are very reactive molecules produced during oxidation events that in turn initiate a chain reaction resulting in cellular damage. Many degenerative diseases in humans, including cancer and central nervous system damage, are caused by free radicals. Scientific evidence indicates that active compounds from natural products can protect cells from free radical damage. As a result
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Retracted: Efficacy of Chinese Medicine Injection for Cardiotoxic Injury of Anthracycline Chemotherapy Drugs: A Network Meta-Analysis of Randomized Controlled Trials. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-11 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/5800575.].
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Retracted: Role of Aromatherapy as a Natural Complementary and Alternative Therapy in Cardiovascular Disease: A Comprehensive Systematic Review. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-11 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/4543078.].
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Retracted: Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-11 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/8644353.].
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Retracted: Antihypertensive and Vasorelaxant Effects of Citrus aurantifolia Linn. Fruit: Proposed Mechanisms. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-11 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/5871424.].
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Retracted: Jujuboside A Ameliorates Myocardial Apoptosis and Inflammation in Rats with Coronary Heart Disease by Inhibiting PPAR-α Signaling Pathway. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-11 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/2285728.].
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Effectiveness of Yoga and Acupuncture in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-6 Carla Andrea Cortés-Ladino, Wanderley Augusto Arias-Ortiz, Alexandra Porras-Ramírez
Introduction. Rheumatoid arthritis is a form of inflammatory joint disease; sometimes, patients need prolonged cycles of nonsteroidal anti-inflammatory drugs and/or glucocorticoids for symptomatology management in addition to traditional disease-modifying drugs and biologics. On some occasions, doses are increased without improvement of symptoms associated with side effects; this is why, on some occasions
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In Vivo Hypolipidemic, Hypoglycemic, Antihyperglycemic, and In Vitro Antioxidant Effects of Podocarpus gracilis Leaf Extract and Fractions in Diabetic Mice Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-6 Wakuma Wakene Jifar, Ahmed S. BaHammam, Yadeta Babu Bayane, Biruk Tafese Moges, Teshome Bekana
Background. Podocarpus gracilis is an evergreen, dioecious tree found in Ethiopia and other African nations. It can reach a height of 60 meters. Without any scientific validation, ethnobotanical studies conducted in Ethiopia revealed that the Podocarpus gracilis plant’s leaf is consumed orally to treat diabetes mellitus. Hence, this study aims to evaluate the in vivo blood glucose level lowering, lipid-lowering
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Ethnoveterinary Study of Plant-Based Remedies for Treating Diseases in Small Ruminants in Maputo Province, Mozambique Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-5 Filomena M. A. Barbosa, Aida C. Cala, Viktor Sevastyanov, Ernesto Boane, Delfina F. Hlashwayo
Small ruminants, particularly goats and sheep, are key livestock species in Mozambique, and their production is mainly undertaken by families. However, small ruminants are often plagued by diseases that can cause considerable economic damage. In this context, traditional remedies, including various plant species, have been widely used to manage these diseases. The aim of this study was to explore the
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Assessing the Impact of High Photon Energy Wavelengths on the Treatment of Chronic Neck and Shoulder Pain Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-4 Travis Sammons, Kirk Gair, Robert G. Silverman, Steve Shanks
The effect of low-level laser therapy with high photon energy wavelengths, green and violet, for treating chronic musculoskeletal pain was examined in the first-ever clinical trial of its kind. Participants (n = 43) underwent a single 13-minute laser session. The primary measure of effectiveness was the change in initial visual analog pain (VAS) scores observed three minutes posttreatment. The success
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Retracted: Total Saikosaponins Attenuates Depression-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats by Regulating the PI3K/AKT/NF-κB Signaling Axis. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/4950414.].
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Retracted: High-Throughput Sequencing Investigation of Bacterial Diversity in Chronic Suppurative Otitis Media and Middle Ear Cholesteatoma. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/9616582.].
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Retracted: Fut7 Promotes Adhesion and Invasion of Acute Lymphoblastic Leukemia Cells through the Integrin/Fak/Akt Pathway. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/1864116.].
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Retracted: Analysis of Influencing Factors for Exercise Ventilation Efficiency of COPD Patients. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/8376085.].
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Retracted: Statins on Spontaneous Intracerebral Hemorrhage: A Meta-Analysis. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/2342159.].
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Retracted: Investigation on Family Support System and Willingness of Patients to Participate in Cardiac Rehabilitation after Percutaneous Coronary Intervention. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/3633188.].
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Retracted: Potential Use of Anti-Cancer Drugs for Treatment of Preeclampsia by Targeting the miRNA-IGF1R-PI3K-AKT Axis. Evid. Based Complement. Altern. Med. (IF 2.65) Pub Date : 2023-10-04 Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2022/3883082.].