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Unused potential of lipid-lowering therapy in very high-risk patients with atherosclerotic cardiovascular disease - a retrospective data analysis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-11 Sarah B. Pohl, Christiane Engelbertz, Holger Reinecke, Nasser M. Malyar, Matthias Meyborg, Tobias J. Brix, Julian Varghese, Katrin Gebauer
Atherosclerotic cardiovascular disease (ASCVD) is the most common cause of death in Europe. Although the 2019 European Society of Cardiology/European Atherosclerosis Society Guidelines for the management of dyslipidaemias claim a target low-density lipoprotein cholesterol (LDL-C) value of <55 mg/dL for very high-risk patients by use of lipid-lowering therapy (LLT) and lifestyle adaptations, the target
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Sex differences in the association of the uric acid to high-density lipoprotein cholesterol ratio with coronary artery disease risk among Chinese nondialysis patients with CKD stages 3–5 Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-09 Yan Yang, Xiao-yan Shen, Hai-xia Tang, Hong Liu, Yi Wen
Evidence has indicated that serum uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with coronary artery disease (CAD). The UA to HDL-C ratio (UHR) has recently drawn attention as a new predictor for metabolic syndrome, inflammation and atherosclerosis. However, the association between the UHR and CAD in nondialysis chronic kidney disease (CKD)
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Eating habits and sleep quality in individuals with type 1 diabetes on continuous glucose monitoring and insulin pump Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-08 Alessandra Corrado, Giuseppe Scida, Marilena Vitale, Benedetta Caprio, Giuseppina Costabile, Eric Annuzzi, Giuseppe Della Pepa, Roberta Lupoli, Lutgarda Bozzetto
Sleep disorders are bidirectionally linked with eating behaviors and glucose metabolism, which could be clinically relevant in type 1 diabetes (T1D). We investigated the relationship between dietary habits and sleep quality in individuals with T1D on insulin pumps and continuous glucose monitoring (CGM). In a cross-sectional study, dietary habits (7-day food diary, EPIC questionnaire) and sleep quality
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A high level of uric acid is associated with long-term adverse cardiovascular outcomes in patients received fractional flow reserve with coronary intermediate stenosis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-08 Fanqi Li, Qiuzhen Lin, Jiabao Zhou, Jiayi Zhu, Yong Zhou, Keke Wu, Qiuyu Li, Donghui Zhao, Qiming Liu
The role of fractional flow reserve (FFR) in coronary intermediate lesions has been widely recommended by guidelines. The effect of uric acid (UA) on cardiovascular events is also well known. However, the relationship between UA and long-term cardiovascular outcomes in patients who received FFR with intermediate lesions remains unknown. We retrospectively included 428 patients who underwent both coronary
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Use of ancient grains for the management of diabetes mellitus: A systematic review with meta-analysis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-07 Camilla Elena Magi, Laura Rasero, Edoardo Mannucci, Guglielmo Bonaccorsi, Francesco Ranaldi, Luigia Pazzagli, Paola Faraoni, Nadia Mulinacci, Stefano Bambi, Yari Longobucco, Ilaria Dicembrini, Paolo Iovino
A systematic review and meta-analysis of published randomized controlled trials was conducted to collate evidence from studies implementing ancient grains and investigate the impact of ancient grain consumption on health outcomes of patients with Diabetes Mellitus (DM). Twenty-nine randomized controlled trials were included, and 13 were meta-analyzed. Interventions ranged from 1 day to 24 weeks; most
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Genetic correlations between liver fat content, metabolic health, and adiposity distribution in the fels longitudinal study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-06 Ariana L. Garza, Miryoung Lee, John Blangero, Cici X. Bauer, Stefan A. Czerwinski, Audrey C. Choh
Hepatic steatosis is known to be heritable, but its genetic basis is mostly uncharacterized. Steatosis is associated with metabolic and adiposity features; recent studies hypothesize that shared genetic effects between these traits could account for some of the unexplained heritability. This study aimed to quantify these genetic associations in a family-based sample of non-Hispanic white adults. 704
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Ultra-processed food consumption and cardiovascular events rate: An analysis from Isfahan Cohort Study (ICS) Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-06 Mohammad Kermani-Alghoraishi, Amin Behrouzi, Razieh Hassannejad, Nizal Sarrafzadegan, Fatemeh Nouri, Mansoureh Boshatam, Hamidreza Roohafza, Fahimeh Haghighatdoost, Masoumeh Sadeghi
The contribution of ultra-processed foods (UPFs) to daily energy intake and, therefore, their health effects may vary between countries. We aimed to investigate the association between UPFs and the incidence risk of cardiovascular events (CVEs) and cardiovascular mortality in the Isfahan cohort study. In 2001, 6504 participants aged ≥35 years were enrolled and followed until 2017. Dietary intake was
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Moderate-intensity constant or high-intensity interval training? Metabolic effects on candidates to undergo bariatric surgery Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-05 Javier Enríquez-Schmidt, Camila Mautner Molina, Mariana Kalazich Rosales, Maximiliano Muñoz, Matias Ruiz-Uribe, Francisca Fuentes Leal, Manuel Monrroy Uarac, Carlos Cárcamo Ibaceta, Daniel J. Fazakerley, Mark Larance, Pamela Ehrenfeld, Sergio Martínez-Huenchullán
Bariatric Surgery is highly effective against obesity. Pre-surgical exercise programs are recommended to prepare the candidate physically and metabolically for surgery-related rapid weight loss. However, the ideal exercise prescription in this population is unknown. This study aimed to compare the metabolic effects of moderate-intensity constant (MICT) vs. a high-intensity interval training (HIIT)
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Development of a machine learning-based model for predicting individual responses to antihypertensive treatments Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-03-04 Jiayi Yi, Lili Wang, Jiali Song, Yanchen Liu, Jiamin Liu, Haibo Zhang, Jiapeng Lu, Xin Zheng
Personalized antihypertensive drug selection is essential for optimizing hypertension management. The study aimed to develop a machine learning (ML) model to predict individual blood pressure (BP) responses to different antihypertensive medications. We used data from a pragmatic, cluster-randomized trial on hypertension management in China. Each patient's multiple visit records were included, and two
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Metabolomics of human umbilical vein endothelial cells-based analysis of the relationship between hyperuricemia and dyslipidemia Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-07 Wen Huang, Min Zhang, Qiong Qiu, Jing Zhang, Chao Hua, Geliang Chen, Hua Xie
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Request of errata corrige for paper: “Hyperuricemia increases the risk of cardiovascular mortality associated with very high HdL-cholesterol level” Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-07 Paolo Palatini
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Associations between bone mineral density and abdominal aortic calcification: Results of a nationwide survey Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-07 Ran Wei, Yixin Zhang, Maoxun Huang, Hulin Piao, Zhaoxuan Gu, Cuilin Zhu
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Association of serum uric acid with all-cause and cardiovascular mortality in chronic kidney disease stages 3-5 Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-06 Jinguo Yuan, Jin Zhao, Yunlong Qin, Yan Xing, Zixian Yu, Yumeng Zhang, Hao Wu, Qiao Zheng, Yueqing Hui, Shuxian Guo, Anjing Wang, Mei Han, Xiaoxuan Ning, Shiren Sun
Background and aims The role of serum uric acid (SUA) in the prognosis of chronic kidney disease (CKD) is inconclusive. To explore the association of SUA level with all-cause and cardiovascular disease (CVD) mortality in patients with CKD. Methods and results Leveraging data from the National Health and Nutritional Examination Survey (NHANES) and linked national death records up to December 31 2019
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The Combination of High Uric Acid and High C-reactive Protein Increased the Risk of Cardiovascular Disease: A 15-year Prospective Cohort Study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-05 Na Li, Shouling Wu, Rong Shu, Haicheng Song, Jierui Wang, Shuohua Chen, Wenhao Yang, Guodong Wang, Jingtao Yang, Xuemei Yang, Gary Tse, Nan Zhang, Liufu Cui, Tong Liu
Background and Aims Uric acid (UA) and C-reactive protein (CRP) may interact synergistically to accelerate the initiation and progression of cardiovascular disease (CVD). This study investigated the effects of a combination of high UA and high CRP on the risks of CVD. Methods and Results A total of 90 270 participants recruited from the Kailuan study were included, who were divided into four groups
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No causal association between Serum vitamin D levels and Diabetes retinopathy: A Mendelianrandomization analysis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-05 Chengcheng Huang, Dan Luo, Mingliang Sun, Guowei Fang, Mengjuan Wei, Yufei Zhang, Jingwu Wang, Yanqin Huang
Background Diabetes retinopathy (DR) is a common microvascular complication of diabetes, and it is the main cause of global vision loss. The current observational research results show that the causal relationship between Vitamin D and DR is still controversial. Therefore, we conducted a Mendelian randomization study to determine the potential causal relationship between serum 25-hydroxyvitamin D (25OHD)
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Impact of fibre supplementation on microbiome and resilience in healthy participants – A randomized, placebo-controlled clinical trial Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-06 Boukje C. Eveleens Maarse, Hannah M. Eggink, Ines Warnke, Sabina Bijlsma, Tim J. van den Broek, Johanneke E. Oosterman, Martien P.M. Caspers, Wilbert Sybesma, Pim Gal, Sebastiaan J.W. van Kraaij, Frank H.J. Schuren, Matthijs Moerland, Femke P.M. Hoevenaars
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Triglyceride glucose index combined with body mass index and its 4-year change with the risk of hypertension in middle-aged and older Chinese: A prospective cohort study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-02 Rui Liu, Lu Wang, Wen Zhong, Lin Xu, Lijuan Li, Chengqi He, Quan Wei
Background and Aim To explore the association of triglyceride glucose index-body mass index (TyG-BMI) and its dynamic changes with the risk of hypertension among middle-aged and older Chinese adults based on a large-sample prospective cohort study. Methods and Results Participants over 45 years old and without a history of hypertension were included from the China Health and Retirement Longitudinal
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Letter to the Editor: Cardiovascular risk and the COVID-19 pandemic: A retrospective observational study in a population of healthcare professionals Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-01 Kashish Zehra Manjee, Satesh Kumar, F.N.U. Samiullah
Abstract not available
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Relation of Body Mass Index to Long-Term Survival and Cardiac Remodeling for Patients Undergoing Mitral Valve Replacement Surgery Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-01 Jimmy JH. Kang, Sabin J. Bozso, Ryaan EL-Andari, Abrar S. Alam, Dana E. Boe, Yongzhe Hong, Richdeep S. Gill, Michael C. Moon, Darren H. Freed, Jayan Nagendran, Jeevan Nagendran
Background and Aims Studies have demonstrated that obesity is paradoxically associated with reduced mortality following cardiac surgery. However, these studies have treated various types of cardiac surgery as a single entity. With mitral valve (MV) surgeries being the fastest-growing cardiac surgical interventions in North America, the purpose of this study was to identify the impact of body mass index
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Performance of the non-laboratory based 2019 WHO cardiovascular disease risk prediction chart in Eastern Sub-Saharan Africa Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-02-01 Anderson Bendera, Keiko Nakamura, Kaoruko Seino, Sharifullah Alemi
Background and aims The World Health Organization (WHO) updated its cardiovascular disease (CVD) risk prediction charts in 2019 to cover 21 global regions. We aimed to assess the performance of an updated non-lab-based risk chart for people with normoglycaemia, impaired fasting glucose (IFG), and diabetes in Eastern Sub-Saharan Africa. Methods and results We used data from six WHO STEPS surveys conducted
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A Causal Relationship between Appendicular Lean Mass and Atrial Fibrillation: A Two Sample Mendelian Randomization Study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-29 Yongfei Song, Zequn Zheng, Jiale Hu, Jiangfang Lian
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Dietary Vitamin C and Vitamin E with the Risk of Aortic Aneurysm and Dissection: A Prospective Population-based Cohort Study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-29 Chuan-Rui Zeng, Jing-Wei Gao, Mao-Xiong Wu, Si You, Zhi-Teng Chen, Qing-Yuan Gao, Zhao-Xi Cai, Pin-Ming Liu, Yang-Wei Cai, Xiao-Tian Liang, Jie-Wen Cai, Guang-Hong Liao, Nuo Chen, Ze-Gui Huang, Jing-Feng Wang, Hai-Feng Zhang, Yang-Xin Chen
Background and Aims The associations between dietary vitamin C (VC), vitamin E (VE) intake and aortic aneurysm and dissection (AAD) remain unclear. This study aimed to prospectively investigate the associations between dietary VC and VE with the incident risk of AAD. Methods and Results A total of 139,477 participants of UK Biobank cohort were included in the analysis. Dietary VC and VE consumptions
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Mitochondrial KATP channel-mediated autophagy contributes to angiotensin II-induced vascular dysfunction in mice Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-26 Xue-Min Yin, Yi-Yi Song, Wen-Yi Jiang, Hao-Tian Zhang, Jing-Wei Chen, Koji Murao, Meng-Xiao Han, Wan-Ping Sun, Guo-Xing Zhang
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Social determinants of health and metabolic syndrome in Colombian older adults Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-26 Eliana Marín-Vargas, José Mauricio Ocampo-Chaparro, Carlos A. Reyes-Ortiz
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Assessing the causal relationships of gut microbial genera with hyperuricemia and gout using two-sample Mendelian randomization Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-24 Yu Lou, Bin Liu, Zhounan Jiang, Xianghui Wen, Siyue Song, Zhijun Xie, Yingying Mao, Tiejuan Shao
Background and Aims The causal relationship between gut microbiota and gout and hyperuricemia (HUA) has not been clarified. The objective of this research was to evaluate the potential causal effects of gut microbiota on HUA and gout using a two-sample Mendelian randomization (MR) approach. Methods and Results Genetic instruments were selected using summary statistics from genome-wide association studies
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Predictive cut-off values for the triglyceride-to-high-density lipoprotein cholesterol ratio to predict metabolic syndrome in the middle-aged Korean population Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-24 Ji Young Kim, Taesic Lee, Tae-Ha Chung
Background and aims The triglyceride-to-high density lipoprotein cholesterol (TG/HDL) ratio is associated with insulin resistance related diseases, including MetS. However, specific TG/HDL values that can predict MetS have not been well identified. In this study, we analyzed both cross-sectional and longitudinal data from two national Korean datasets to obtain TG/HDL cut-off values that can identify
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Effect of sesame supplementation on body composition, and lipid profile in patients with type 2 diabetes: A Systematic Review and Meta-analysis of randomized controlled trials Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-22 Mahdi Vajdi, Hooria Seyedhosseini-Ghaheh, Shirin Hassanizadeh, Negar mostafavi, Mahsa Khajeh, Fatemeh Pourteymour Fard Tabrizi, Gholamreza Askari
Aims The aim of this study was to conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) that evaluated the impact of sesame supplementation on body weight (BW), body mass index (BMI), triglycerides (TGs), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), and high-density lipoprotein-cholesterol (HDL-C) in patients with type 2 diabetes mellitus (T2DM)
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Prevalence and determinants of self-reported low-fat-, low-salt-, and vegetarian diets in patients with cardiovascular disease between 1996 and 2019 Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-19 L.L.F. Hoes, J.M. Geleijnse, N.E. Bonekamp, J.A.N. Dorresteijn, M.G. van der Meer, Yvonne.T. van der Schouw, Frank L.J. Visseren, Charlotte Koopal
Background and aims Guidelines no longer recommend low-fat diets and currently recommend more plant-based diets to reduce atherosclerotic cardiovascular disease (ASCVD) risk. Furthermore, these guidelines have consistently recommended salt-reduced diets. This article describes current self-reported use and time-trends in the self-reported use of low-fat, low-salt and vegetarian diets in ASCVD patients
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Asymmetric dimethylarginine (ADMA) is associated with reduced myocardial mechano-energetic efficiency in hypertensive subjects Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-17 Chiara M.A. Cefalo, Alessia Riccio, Teresa Vanessa Fiorentino, Mattia Massimino, Gaia Chiara Mannino, Elena Succurro, Maria Perticone, Angela Sciacqua, Francesco Andreozzi, Francesco Perticone, Giorgio Sesti
Background and aims Our prior study showed that endothelial dysfunction contributed to reduced myocardial mechano-energetics efficiency (MEEi) independently of several confounders. Reduced activity of endothelial nitric oxide synthase may be due to increased levels of the endogenous inhibitor asymmetric dimethylarginine (ADMA). The impact of ADMA on myocardial MEEi has not been determined yet. This
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Time-Domain Heart Rate Dynamics in the Prognosis of Progressive Atherosclerosis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-14 Rahul Kumar, Yogender Aggarwal, Vinod Kumar Nigam, Rakesh Kumar Sinha
Background and Aim The regular uptake of a high-fat diet (HFD) with changing lifestyle causes atherosclerosis leading to cardiovascular diseases and autonomic dysfunction. Therefore, the current study aimed to investigate the correlation of autonomic activity to lipid and atherosclerosis markers. Further, the study proposes a support vector machine (SVM) based model in the prediction of atherosclerosis
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Prediction of Cardiac Death in Patients with Hypertrophic Cardiomyopathy Using Plasma Adipokine Levels Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-18 Keitaro Akita, Kohei Hasegawa, Michael A. Fifer, Albree Tower-Rader, Jeeyoun Jung, Mathew S. Maurer, Muredach P. Reilly, Yuichi J. Shimada
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Body Composition Markers are Associated with Changes in Inflammatory Markers but not Vice Versa: A Bi-directional Longitudinal Analysis in a Population-based Sample Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-18 Saima Bibi, Muhammad Naeem, Mohammed Farah Mahmoud Mousa, Martin Bahls, Marcus Dörr, Nele Friedrich, Matthias Nauck, Robin Bülow, Henry Völzke, Marcello RP. Markus, Till Ittermann
Background and Aim Growing body of evidence consistently link obesity and inflammation, Although the direction of the association is still unclear. We aimed to investigate longitudinal associations of body anthropometric, composition and fat distribution parameters with inflammatory markers and vice versa. Method and Results We used data from 2464 individuals of the SHIP-TREND cohort with a median
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Association between serum uric acid and deep venous thrombosis in European populations: a two-sample Mendelian randomization study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-17 Yue Liu, Shiwei Li, Xinxin Zhang, Bo Huang, Yuhong Fu, Xin Li, Jingqiu Cui
Background and Aim Previous experimental and observational studies showed that serum uric acid (SUA) was associated with deep venous thrombosis (DVT), but the causal relationship is unclear. This study aimed to explore the potential causal association between SUA and DVT. Methods and Results We designed a two-sample Mendelian randomization (MR) analysis by using summary-level data from large genome-wide
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The impact of of urinary albumin-creatinine ratio and glomerular filtration rate on long-term mortality in patients with heart failure: the National Health and Nutrition Examination Survey 1999-2018 Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-17 Xu Xiaoqun, Cai Long, Zhu Xinyu, Wang Hanxin, Chen Tielong, Houyong Zhu, Kaiqing Lin
Background and Aims The urinary albumin‒creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) are important markers of renal dysfunction, but few studies have simultaneously examined their impact on long-term mortality in patients with heart failure (HF). Methods and Results This study included patients with HF from the National Health and Nutrition Survey from 1999 to 2018. The fully
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Left ventricular hypertrophy phenotype to predict incident atrial fibrillation: The Multi-Ethnic Study of Atherosclerosis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-17 Lili Wang, Jiayi Yi, Zeming Zhou, Jiamin Liu, Yan Li, Aoxi Tian, Xiangpeng Ren, Xin Zheng
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KETOGENIC DIET FOR EPILEPSY AND OBESITY: IS IT THE SAME? Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-14 A. Tagliabue, M. Armeno, K.A. Berk, M. Guglielmetti, C. Ferraris, J. Olieman, E. van der Louw
The term “ketogenic diet” (KD) is used for a wide variety of diets with diverse indications ranging from obesity to neurological diseases, as if it was the same diet. This terminology is confusing for patients and the medical and scientific community. The term “ketogenic” diet implies a dietary regimen characterized by increased levels of circulating ketone bodies that should be measured in blood
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Bisphenol A and cardiometabolic risk in adolescents: data from the Generation XXI cohort Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-13 Vânia Magalhães, Milton Severo, Sofia Almeida Costa, Daniela Correia, Catarina Carvalho, Duarte Torres, Susana Casal, Sara Cunha, Carla Lopes
Background and aims Bisphenol A (BPA), an endocrine disruptor widely used in food contact materials, has been linked to a worse health profile. This study intends to estimate the association between BPA exposure and cardiometabolic patterns at adolescence. Methods and results Data from the Portuguese population-based birth cohort Generation XXI at the age of 13 were used (n=2386 providing 3-day food
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A high dietary acid load can potentially exacerbate cardiometabolic risk factors: an updated systematic review and meta-analysis of observational studies Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-13 Shamim Dolati, Soha Razmjouei, Amir Hossein Faghfouri, Amir Hossein Moridpour, Mohammad Alizadeh
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The Association Between Time-Restricted Eating and Arterial Stiffness Status in Community-Dwelling Elderly Chinese Individuals Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-11 Cheng Chen, Yaqing Zheng, Yahui Wu, Kai Zheng, Yue Wang, Chuanjun Huang, Jiangling Guo, Yiqiong Qi, Xiaoyu Chen, Qiongying Tao, Jiayi Zhai, Peipei Han, Yanxia Pan, Qi Guo
Background and aims Emerging studies indicate that time-restricted eating (TRE) may protect against cardiovascular disease (CVD); however, studies performed in elderly adults are limited. This study aimed to analyze the association of TRE with arterial stiffness (AS) in community-dwelling elderly Chinese individuals. Methods and results This cross-sectional study recruited 3487 participants aged ≥
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Mediterranean diet and a health behavior index in relation to cardiovascular biomarkers: DATA from the health and Retirement study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-09 Ionas Papassotiriou, Elena Riza, Vasiliki Benetou, Philippos Orfanos
Background and Aim Although lifestyle factors have been repeatedly examined for their role on cardiovascular diseases, their composite effect has not been frequently explored. We aimed to investigate the relation of dietary patterns (DPs) and a health behavior index (HBI) with cardiovascular biomarkers. Methods and Results A cross-sectional analysis with data from 3,461 US residents, participants in
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Cardiovascular health, sleeping duration, and risk of mortality in current and former smokers Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-08 Bowei Yu, Ying Sun, Yuefeng Yu, Yuetian Yu, Yuying Wang, Bin Wang, Xiao Tan, Yu Wang, Yingli Lu, Ningjian Wang
Background and Aims To investigate the associations of ideal cardiovascular health metrics (ICVHMs) with all-cause mortality among former and current smokers compared with never smokers. Methods and Results A total of 378,147 participants [mean age (SD) years: 56.3 (8.1); 47.2% men] were included from the UK Biobank cohort. The ICVHMs were combined Life’s simple 7 from the American Heart Association
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Triglyceride/high-density lipoprotein cholesterol ratio may be a better index of cardiometabolic risk in women than in men in Japan Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-05 Shigemasa Tani, Kazuhiro Imatake, Yasuyuki Suzuki, Tsukasa Yagi, Atsuhiko Takahashi, Masaki Monden, Naoya Matsumoto, Yasuo Okumura
Background and Aims Few data exist regarding the gender differences in the relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio and cardiometabolic risk leading to atherosclerotic cardiovascular disease (ASCVD). We investigated, by gender, the association between the TG/HDL-C ratio and metabolic syndrome (MetS) and its components in the Japanese, who are less obese
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Small ischemic lesions accompanying intracerebral hemorrhage: The underlying influence of old lacunes and polyunsaturated fatty acids Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-05 Motohiro Okumura, Takeo Sato, Junichiro Takahashi, Tatsushi Kokubu, Ryoji Nakada, Tomomichi Kitagawa, Maki Tanabe, Hiroki Takatsu, Asako Onda, Teppei Komatsu, Kenichi Sakuta, Kenichiro Sakai, Tadashi Umehara, Hidetaka Mitsumura, Yasuyuki Iguchi
Background and Aims Small ischemic lesions (SILs) accompanying intracerebral hemorrhage (ICH) might be induced by small-vessel vulnerability and hypercoagulation. Some polyunsaturated fatty acids (PUFAs) have been associated with hypercoagulation in cardiovascular diseases. Our aim here is to determine how pre-existing small-vessel disease (SVD) and PUFAs may affect SILs. Methods and Results We screened
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Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-05 Katharina S. Weber, Sabrina Schlesinger, Alexander Lang, Klaus Straßburger, Haifa Maalmi, Anna Zhu, Oana-Patricia Zaharia, Alexander Strom, Gidon J. Bönhof, Janina Goletzke, Sandra Trenkamp, Robert Wagner, Anette E. Buyken, Wolfgang Lieb, Michael Roden, Christian Herder
Background and Aims Differences of dietary pattern adherence across the novel diabetes endotypes are unknown. This study assessed adherence to pre-specified dietary patterns and their associations with cardiovascular risk factors, kidney function, and neuropathy among diabetes endotypes. Methods and Results The cross-sectional analysis included 765 individuals with recent-onset (67%) and prevalent
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Association of sex-specific body mass index and waist circumference trajectories with non-alcoholic fatty liver disease incidence: Based on growth mixture modeling Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-05 Tengrui Cao, Chao Tong, Qiang Li, Yumei Han, Aheyeerke Halengbieke, Xuetong Ni, Bo Gao, Deqiang Zheng, Xinghua Yang
Background and Aims Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease. The relationship between the trajectories of obesity indicators and incident NAFLD is unknown. Therefore, this study aims to explore the sex-specific association between the trajectories of obesity indicators and the incidence of NAFLD. Methods and Results In total, 9,067 participants were recruited for
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Impact of Triglyceride-Glucose Index on Intracoronary Thrombus Burden in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-04 Uğur Köktürk, Orhan Önalan, Mustafa Umut Somuncu, Özgür Akgül, Begüm Uygur, Hamdi Püşüroğlu
Background and Aims We aimed to investigate the relationship between triglyceride glucose (TyG) index and intracoronary thrombus burden in patients with ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). Methods and Results A total of 468 consecutive patients who were admitted with STEMI and underwent primary PCI were included in the study. TyG
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A cross-sectional study of the relationship between physical activity, diet quality, and high-sensitivity C-reactive protein in US adults Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2024-01-03 Furong Xu, Jacob E. Earp, Matthew J. Delmonico, Ingrid E. Lofgren, Deborah Riebe
Background and Aims High-sensitivity-C-reactive protein (hs-CRP) is associated with many diseases, especially cardiovascular disease (CVD). Research into the independent and integrated relationships of physical activity and diet quality with hs-CRP across sex-specific cohorts is lacking. Methods and Results National Health and Nutrition Examination Survey data (2015-2018) was used to examine the relationship
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Uric Acid Levels and Heart Failure: A Mendelian Randomization Study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-30 Jiaqi Zheng, Kaiwen Cen, Jiajun Zhang, Huan Zhang, Mingguang Zhao, Xiaowen Hou
Background and Aims Uric acid, the end-product of purine metabolism within the human body, has been the subject of studies exploring its potential association with cardiovascular and cerebrovascular diseases. However, the precise relationship between uric acid levels and heart failure remains elusive. Methods and Results In this particular study, aggregated data from genome-wide association studies
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Impaired Sensitivity to Thyroid Hormones Is Associated With Different Grades of Hypertension: a multicenter cross-sectional study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-30 Lu Yu, Guangwei Pan, Zhu Li, Lin Li, Shan Gao, Fanfan Liu, Yuanyuan He, Yijia Liu, Yutong Liu, Jia Zhao, Rongrong Yang, Chunquan Yu
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Visceral adiposity associated with incidence and development trajectory of cardiometabolic diseases: a prospective cohort study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-30 Qida He, Yu Wang, Zhaolong Feng, Jiadong Chu, Tongxing Li, Wei Hu, Xuanli Chen, Qiang Han, Na Sun, Siyuan Liu, Hongpeng Sun, Yueping Shen
Background and Aims There is a lack of literature concerning the effects of visceral adipose on the development of first cardiometabolic disease (FCMD) and its subsequent progression to cardiometabolic multimorbidity (CMM) and mortality. Methods and Results 423,934 participants from the UK Biobank with different baseline disease conditions were included in the analysis. CMM was defined as the simultaneous
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Uric acid to HDL ratio: a marker for predicting incidence of metabolic syndrome in patients with type II diabetes Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-30 Gholamrerza Bazmandegan, Mohammad hasan Dehghani, Maryam Karimifard, Mahmood Kahnooji, Parisa Balaee, Mohammad Ali Zakeri, Zahra Kamiab
Background and Aim Metabolic syndrome (MetS) refers to existence of a set of risk factors for developing cardiovascular disease and diabetes. Recently, uric acid to HDL ratio has attracted attention in predicting development of diabetes and incidence of metabolic syndrome in diabetic individuals. This study was performed to investigate UHR in patients with type II diabetes as a predicting factor for
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Spatiotemporal Trends in the Burden of Aortic Aneurysms Caused by High Sodium Intake from 1990 to 2019: A Global, Regional, and National Analysis Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-23 Yu Zhang, Jifu Lai
Background and Aims This study, drawing on Global Burden of Disease (GBD) data, examines spatiotemporal trends in mortality and disability-adjusted life years (DALYs) linked to aortic aneurysm (AA) from high sodium intake. The aim is a comprehensive analysis globally, regionally, and nationally spanning 1990 to 2019. Methods and Results Quantifying AA deaths and DALYs due to high sodium intake, incorporating
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Translating trial results into interpretable risk estimates: systematic analysis of cardiorenal outcome trials of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-20 Alessandro Rizzi, David E. Kloecker, Dario Pitocco, Kamlesh Khunti, Melanie J. Davies, Francesco Zaccardi
Background and Aims In a randomised controlled trial (RCT), the between-arm difference in the average probability of an event per unit of time (i.e., yearly incidence risk difference, YIRD) is an easy-to-interpret treatment effect metric. We aimed to quantify the YIRD in cardiorenal RCTs of GLP-1RAs or SGLT-2is. Methods and Results We digitally searched for RCTs published up to March 1st, 2023, including
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Nonlinear relationship between body mass index and serum uric acid: an observational and Mendelian randomization study among Chinese adults Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-20 Yanqi Fu, Yuefeng Yu, Yuying Wang, Ying Sun, Kun Zhang, Fei Xu, Ningjian Wang, Bin Wang, Yingli Lu
Background and Aims Conflicting evidence exists on the relationship between body mass index (BMI) and serum uric acid (SUA), and importantly, the causal role of BMI in SUA remains unclear. We aimed to evaluate the BMI-SUA relationship and its causality among Chinese adults using observational and Mendelian randomization (MR) analyses. Methods and Results Study included 6,641 adults from East China
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Circulating miR-423-5p levels are associated with carotid atherosclerosis in patients with chronic kidney disease Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-22 Yuzhi Huang, Xueying Feng, Heze Fan, Jian Luo, Zihao Wang, Yuxuan Yang, Wenbo Yang, Wenjiao Zhang, Juan Zhou, Zuyi Yuan, Ying Xiong
Background and aims Carotid atherosclerosis is associated with an elevated risk of stroke in patients with chronic kidney disease. However, the molecular basis for the incidence of carotid atherosclerosis in patients with CKD is poorly understood. Here, we investigated whether circulating miR-423-5p is a crucial link between CKD and carotid atherosclerosis. Methods and results We recruited 375 participants
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From Adolescence to Adulthood: Mediterranean Diet Adherence and Cardiometabolic Health in a Prospective Cohort Study Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-21 Niloufar Saber, Farshad Teymoori, Mitra Kazemi Jahromi, Ebrahim Mokhtari, Mostafa Norouzzadeh, Hossein Farhadnejad, Parvin Mirmiran, Fereidoun Azizi
Background and Aims Recent investigations suggest that specific dietary patterns during adolescence may predict cardiometabolic complications later in life. In this study, we aimed to examine the association between Mediterranean diet score(MDS) during adolescence and cardiometabolic outcomes when participants reached adulthood. Methods and Results This cohort study was conducted on 668 subjects, aged
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Prevalence and clinical characteristics of diabetic cardiomyopathy in patients with acute heart failure Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-19 Kenichi Matsushita, Kazumasa Harada, Takashi Kohno, Hiroki Nakano, Daisuke Kitano, Junya Matsuda, Makoto Takei, Hideaki Yoshino, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
Background and Aims Diabetic cardiomyopathy refers to cases of diabetes mellitus (DM) complicated by cardiac dysfunction in the absence of cardiovascular disease and hypertension. Its epidemiology remains unclear due to the high rate of coexistence between DM and hypertension. Therefore, this study aimed to examine the prevalence and clinical characteristics of diabetic cardiomyopathy among patients
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Editorial Board Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-23
Abstract not available
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Comparing a range of potassium-enriched low sodium salt substitutes to common salt: results of taste and visual tests in South African adults Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-20 Simone H. Crouch, Lisa J. Ware, Shane A. Norris, Aletta E. Schutte
Background and aims Potassium-enriched low-sodium salt substitutes (LSSS), which replace a proportion of sodium chloride (NaCl) with potassium chloride (KCl), have been shown to reduce blood pressure and offer a potential solution to address the high burden of hypertension in South Africa. However, it is unknown which proportions of KCl in LSSS are acceptable. We compared the taste and visual acceptability
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Cardiometabolic risk assenssment: a school-based study in Brasilian adolescent Nutr. Metab. Cardiovascular Dis. (IF 3.9) Pub Date : 2023-12-20 Ribanna Aparecida Marques Braga, Ilana Nogueira Bezerra, Maria Dinara Araújo Nogueira, Amanda de Moura Souza, Géssica de Souza Martins, Kaluce Gonçalves de Sousa Almondes, Luis Alberto Moreno, Carla Soraya Costa Maia