-
Infantile inflammatory bowel disease in three Syrian infants: a case series J. Med. Case Rep. Pub Date : 2024-03-18 Afif Alshwaiki, Ranim M. H. D. Samir Nakhal, Ali Alakbar Nahle, Hussein Hamdar, Nafiza Martini, Jaber Mahmod
Inflammatory bowel diseases, consisting of Crohn’s disease and ulcerative colitis, are chronic bowel relapsing inflammatory disorders. Inflammatory bowel diseases begin rarely in infants. Approximately 25% of patients with inflammatory bowel diseases present before the age of 20 years. Very early-onset inflammatory bowel disease occurs before the age of 6 years; infantile inflammatory bowel diseases
-
Two stents’ dislodgement in the left main coronary artery: a case report J. Med. Case Rep. Pub Date : 2024-03-18 Salim Arous, Hatim Zahidi, Mohamed El Ghali Benouna, Rachida Habbal
Stent dislodgement is a life-threatening complication that can result in coronary artery embolization, stent thrombosis, acute myocardial infarction, and even death. Severely angulated, heavily calcified, and previously stented coronary arteries are associated risk factors. With the development of different lesion preparation techniques and the drug eluting stent era, the reported incidence of stent
-
An epidermal growth factor receptor compound mutation of L858R with S768I in advanced non-small-cell lung cancer: a case report J. Med. Case Rep. Pub Date : 2024-03-18 Sara Boukansa, Ismail Mouhrach, Fatima El Agy, Laila Bouguenouch, Mounia Serraj, Bouchra Amara, Yassine Ouadnouni, Mohamed Smahi, Badreeddine Alami, Nawfel Mellas, Zineb Benbrahim, Hinde El Fatemi
In the current treatment landscape for non-small cell lung cancers, epidermal growth factor receptor-tyrosine kinase inhibitors have emerged as a well-established treatment option for patients with advanced or metastatic disease. This is particularly true for those with commonly occurring epidermal growth factor receptor mutations. However, the therapeutic efficacy of these agents for so-called rare
-
Indoxacarb poisoning causing methemoglobinemia treated with parenteral vitamin C: a case report J. Med. Case Rep. Pub Date : 2024-03-17 Lokesh Koumar Sivanandam, H. Arunkumar, Pranay Marlecha, Varsha Madamanchi, Chanchal Maheshwari, Mohammed Quader Naseer, Vivek Sanker, Tirth Dave
This case study reports on a suicide attempt involving indoxacarb and vitamin C. Indoxacarb is a neurotoxic insecticide used in agriculture and as a flea controller in pets. Cotton, vegetables, and fruits are treated with indoxacarb, an insecticide that can be applied both indoors and outdoors. It causes skin allergies, methemoglobinemia, and hemolytic anemia. It is also attributed to allergic reactions
-
Giant stone adhered in the vaginal cavity in a female patient with type 2 diabetes mellitus: a case report J. Med. Case Rep. Pub Date : 2024-03-17 César Alas-Pineda, Kristhel Gaitán-Zambrano, Génesis Sarahí Chávez Paredes, Gloria Cárcamo-Portillo, Hilda A. Argeñal-Guifarro, Luis Zúñiga-Girón
Bladder lithiasis comprises 5% of urological lithiasis. Large bladder stones associated with vesicovaginal fistulas are rare, and the risk factors are not an isolated process. There are metabolic comorbidities associated with this pathology, including diabetes mellitus. A 70-year-old Mestizo patient is presented, reporting dysuria, pollakiuria, and abdominal pain of 4 months of evolution, located in
-
Fulminant myocarditis during postoperative adjuvant chemotherapy for lung cancer with atezolizumab: a case report J. Med. Case Rep. Pub Date : 2024-03-16 Takuya Tokunaga, Masaya Aoki, Koki Maruyama, Yuto Nonaka, Kota Kariatsumari, Koichi Sakasegawa, Kazuhiro Ueda
Postoperative adjuvant systemic therapy with atezolizumab for lung cancer has been reported to be effective. Although myocarditis is a rare immune adverse event associated with atezolizumab, it can have a serious course and should be treated with caution. We herein report a case of fulminant myocarditis during adjuvant systemic therapy with atezolizumab. The patient was a 49-year-old Asian woman. She
-
Bilateral vertebral artery injury leads to brain death following traumatic brain injury: a case report J. Med. Case Rep. Pub Date : 2024-03-16 Vera Irawany, Vizzi A. F. Nasution, Noorcahya Amalia
Vertebral artery injury is a rare condition in trauma settings. In the advanced stages, it causes death. A 31-year-old Sundanese woman with cerebral edema, C2–C3 anterolisthesis, and Le Fort III fracture after a motorcycle accident was admitted to the emergency room. On the fifth day, she underwent arch bar maxillomandibular application and debridement in general anesthesia with a hyperextended neck
-
Synovial sarcoma of the dorsal aspect of the hand: a case report J. Med. Case Rep. Pub Date : 2024-03-15 Farhad Bizhanzadeh, Fateme Heydari, Ronak Rashedi, Mohammadhosein Ramezanirad, Amir Reza Bahadori
Synovial sarcoma is a rare soft tissue sarcoma, with incidences of 0.81/1,000,000 in children and 1.42/1,000,000 in adults. It is most commonly found in soft tissue and rarely in bone. It often has a slow growth pattern and a benign radiologic appearance. This study reports a case of metacarpal synovial sarcoma occurring in the hand-wrist of a 32-year-old Iranian man presented with the chief complaint
-
Biomechanical gait analysis and rehabilitation in a traumatic hallux deficit patient: a case report J. Med. Case Rep. Pub Date : 2024-03-15 Naoki Doi, Todd Pataky, Hiroshige Tateuchi, Momoko Nagai-Tanima, Tomoki Aoyama
The hallux plays a crucial role in maintaining standing balance and facilitating forward and backward movements during gait. A 21-year-old Japanese patient, suffering from a traumatic hallux deficit with only a portion of the basal phalanx intact, underwent rehabilitation treatment. The thenar area exhibited instability, leading to impaired balance and walking difficulties. Biomechanical assessment
-
Robotic resection for splenic artery aneurysm associated with neurofibromatosis type 1: a case report J. Med. Case Rep. Pub Date : 2024-03-14 Akihiko Ueda, Kenta Saito, Hiromichi Murase, Tomokatsu Kato, Hiroyuki Imafuji, Mamoru Morimoto, Ryo Ogawa, Hiroki Takahashi, Yoichi Matsuo, Shuji Takiguchi
Neurofibromatosis type 1 is an autosomal-dominant disease characterized by café-au-lait spots and neurofibromas, as well as various other symptoms in the bones, eyes, and nervous system. Due to its connection with vascular fragility, neurofibromatosis type 1 has been reported to be associated with vascular lesions, such as aneurysms. However, there have been few reports of abdominal visceral aneurysms
-
Spontaneous knot formation complication of double J: two case reports J. Med. Case Rep. Pub Date : 2024-03-13 Ahmet Can Kolu, Serkan Akan
Use of ureteral stents has become an integral part of urological practice. However, it also brought with it many complications. Double J (DJ) stent knotting is a rare stent complication, and only a few cases have been reported in the literature. Although the exact cause is unknown and, in the literature, it is generally thought that knots occur due to traction. In this case report we present for the
-
Nonketotic hyperglycemia hemichorea and hemiballismus: a case report J. Med. Case Rep. Pub Date : 2024-03-12 Abhishek Dixit
Diabetic striatopathy, also known as hyperglycemic hemichorea-hemiballismus, is a rare movement disorder associated with nonketotic hyperglycemia in patients with poorly controlled diabetes mellitus. The pathophysiology is not fully elucidated but may involve hyperviscosity, ischemia, and alterations in basal ganglia neurotransmitters. We present a case of a 64-year-old Asian female patient with longstanding
-
Recurrent syncope due to ischemia with non-obstructive coronary artery disease: a case report J. Med. Case Rep. Pub Date : 2024-03-12 Bihan Huang, Xueying Han, Peiyi Xie, Shaoyuan Chen
Ischemia with non-obstructive coronary artery disease is a prevalent form of ischemic heart disease. The majority of ischemia with non-obstructive coronary artery disease cases are attributed to underlying factors such as coronary microvascular dysfunction (CMD) and/or coronary artery spasm. Ischemia with non-obstructive coronary artery disease can present with various clinical manifestations. Recurrent
-
Segmental artery angioembolization as an efficient treatment modality for delayed hematuria with normal angiography: two case reports J. Med. Case Rep. Pub Date : 2024-03-12 Alireza Pakdel, Fardin Asgari, Razman Arabzadeh Bahri, Seyed Mohammad Kazem Aghamir
Percutaneous nephrolithotomy is the most commonly used modality for the removal of kidney stones larger than 2 cm in size. Like other stone removal methods, percutaneous nephrolithotomy also has some complications, including bleeding and delayed hematuria. These complications are improved with conservative management and bed rest most of the time. However, it may require more invasive treatments. Angioembolization
-
Left atrial myxoma with cardiogenic shock following a myocardial infarction: a case report J. Med. Case Rep. Pub Date : 2024-03-11 Ian Lancaster, Tara Hrobowski-Blackman, Deep Patel, Lubna Chatoor, Joshini Simon, Andrew Willinger
Myxomas are the most common primary cardiac tumor and typically originate in the left atrium. Atrial myxomas may present following complications of obstruction and emboli. If an atrial myxoma goes untreated, complications such as congestive heart failure, embolic stroke, and sudden death can occur. A 58-year-old Caucasian male presented following a cardiac arrest. He was taken emergently to the cardiac
-
Computed tomography angiography of liver alveococcosis: a case report J. Med. Case Rep. Pub Date : 2024-03-11 Saodatkhon Magzumova, Umidjon Isroilov, Nigora Djuraeva, Zarina Khaybullina, Aybek Amirkhamzaev, Nargiza Vakhidova, Khanum Abdukhalimova, Alisher Sultanov, Bekhzod Abdullaev
Alveococcosis, helminthiasis caused by the larvae of Alveococcus multilocularis, is characterized by the formation of parasitic nodes in the liver. This clinical case is a rare occurrence of liver alveococcosis in Uzbekistan. We present a case of a 33-year-old Asian woman from Uzbekistan who complained of discomfort in the epigastric region and right hypochondrium, along with general weakness. She
-
Nephrotic syndrome with rectus sheath hematoma: a case report J. Med. Case Rep. Pub Date : 2024-03-10 Ai Fujii, Yuto Matsuda, Tomohisa Yabe, Hayashi Norifumi, Keiji Fujimoto, Masahide Yamazaki, Hitoshi Yokoyama, Kengo Furuichi
Rectus sheath hematoma is a rare presentation often associated with abdominal trauma and anticoagulant therapy. Here, we present a patient with severe rectus sheath hematoma accompanied by nephrotic syndrome who achieved significant clinical improvement without the need for invasive treatment. A 72-year-old Japanese woman was referred to our hospital for the treatment of nephrotic syndrome. She was
-
Familial primary calcific band-shaped keratopathy with late onset systemic disease: a case series and review of the literature J. Med. Case Rep. Pub Date : 2024-03-10 Parisa Abdi, Hassan Asadigandomani, Arman Amirkhani, Sara Taghizadeh, Zohreh Nozarian
Familial calcific band-shaped keratopathy (BSK) is a very rare disease, with no underlying cause. There is no underlying disease in this form of the disease. This article introduces a family with seven children, three of whom were diagnosed with familial primary calcific BSK. One of them developed a systemic disease 38 years after ocular manifestation. In this case report, three Iranian siblings from
-
Conversion of failed revision total knee arthroplasty in arthrodesis with modular nail maintaining the uncemented femoral stem in patient with extensor mechanism insufficiency: a case report J. Med. Case Rep. Pub Date : 2024-03-09 Giulio Maria Marcheggiani Muccioli, Domenico Alesi, Vito Gaetano Rinaldi, Tosca Cerasoli, Davide Valente, Stefano Zaffagnini
The transition from revision total knee arthroplasty (RTKA) to arthrodesis involves the replacement of cemented femoral and tibial stems with a modular nail designed for arthrodesis. This conversion process is associated with challenges such as bone loss, blood loss, and prolonged surgical durations. Effectively addressing these complexities through a less invasive surgical approach could be pivotal
-
Profound postinduction hypotension precipitated by immune checkpoint inhibitors: a case report J. Med. Case Rep. Pub Date : 2024-03-09 Lu Che, Afang Zhu, Wen Chen, Chunhua Yu
With the increasing use of immune checkpoint inhibitors (ICIs) in cancer therapy, perioperative healthcare professionals need to be vigilant about potential immune-related adverse events (irAEs). We report a case of severe postinduction hypotension in a patient undergoing laparotomy due to suspected intraabdominal bleeding from gastric cancer and Krukenberg tumors, caused by unrecognized hypothyroidism
-
Primary extraskeletal intradural Ewing sarcoma with acute hemorrhage: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-03-09 HusamEddin Salama, Lila H. Abu-Hilal, Mayar Idkedek, Abdalwahab Kharousha, Mohand Abulihya, Hafez Nimer
Spinal cord tumors present a challenge in diagnosis and treatment due to their varied histopathological characteristics. While Ewing sarcoma is a rare malignant tumor typically originating from skeletal bone, cases of primary intradural extraskeletal Ewing sarcoma are exceptionally rare. The similarity of its presentation to other spinal tumors further complicates its identification and management
-
Treatment options and outcomes for delayed scapular anatomical neck fractures: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-03-09 Farzad Amouzadeh Omrani, Mohammad Khak, Reza Tavakoli Darestani, Sina Afzal, Mojtaba Baroutkoub, Mahdi Aghaalikhani, Hasan Barati
Scapular anatomical neck fractures are among the most infrequent shoulder girdle fractures. Only seven radiologically confirmed cases of scapular anatomical neck fractures have been documented in the literature to date, of which only one case underwent delayed surgery. A 34-year-old male Persian patient with morbid obesity was diagnosed with a scapula anatomical neck fracture after a motor vehicle
-
Teriparatide and clodronate combination as a potential treatment for complex regional pain syndrome type I in delayed consolidation after foot surgery: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-03-08 F. Di Sacco, D. Antognetti, G. Ciapini, M. Nicastro, M. Scaglione, V. Bottai
Complex regional pain syndrome type I is a pathological condition characterized by an exaggerated response of tissues to low or moderate pain stimuli. The exact pathogenesis and optimal medical treatment for complex regional pain syndrome type I are still not fully understood, although bisphosphonates have shown positive effects in reducing pain. Foot surgery can be complicated by the development of
-
Primary seronegative intermuscular hydatidosis in a child, an infection that should be approached like a tumor: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-03-08 Reza Tavakoli Darestani, Gholamhossein Kazemian, Sina Afzal, Mojtaba Baroutkoub, Mahdi Aghaalikhani, Farzad Amouzadeh Omrani
Intermuscular hydatid cyst is one of the rarest types of hydatid cyst, and as far as we know, only nine cases were reported in the literature before this study. We present a 10-year-old Iranian child with an intermuscular cystic mass in the medial-distal thigh. Despite the typical imaging findings, the patient's serological and hematological tests were negative for hydatid cyst. The cyst underwent
-
Orbital infarction syndrome following mechanical thrombectomy in internal carotid artery occlusion: a case report J. Med. Case Rep. Pub Date : 2024-03-08 Binh Q. Tran, Lanh C. Nguyen, Tinh T. Trinh, An T. T. Vo, Minh V. Do, Minh Q. Tran, Khanh C. Tran, Loan H. T. Tran, Duc T. Ha
Orbital ischemic syndrome is a rare entity. The clinical signs typically demonstrate acute loss of visual acuity, chemosis, proptosis, ptosis, and total ophthalmoparesis. We report a case of a man who suffered an acute internal carotid artery occlusion and developed orbital ischemic syndrome after a mechanical thrombectomy. A 57-year-old Vietnamese (Kinh ethnicity) man was brought to the emergency
-
Safety and efficacy of remifentanil target-controlled infusion for conscious sedation in a pregnant woman: a case report J. Med. Case Rep. Pub Date : 2024-03-07 Camilla Munafo’, Antonella Loperfido, Fulvio Mammarella, Arianna Crosti, Federico Iannilli, Francesca Romana Millarelli, Gianluca Bellocchi, Luigi Tritapepe
Every year 2% of pregnant women undergo nonobstetric surgical interventions worldwide. According to the American College of Obstetricians and Gynecologists Committee on Obstetric Practice, pregnant women should never be denied the most appropriate surgical treatment, regardless of the trimester of pregnancy. However, additional attention should be paid during the first trimester since it has the highest
-
Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature J. Med. Case Rep. Pub Date : 2024-03-07 Feryel Letaief Ksontini, Yosra Zaimi, Isaad Nefzi, Salim Khrouf, Myriam Ayari, Sonia Sghaier, Asma Zidi, Houcine Magherbi, Mouna Ayadi
Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities
-
Conjoined lumbosacral nerve root: a case report J. Med. Case Rep. Pub Date : 2024-03-07 Yasutaka Takagi, Hiroshi Yamada, Hidehumi Ebara, Hiroyuki Hayashi, Hiroyuki Inatani, Kazu Toyooka, Akari Mori, Yoshiyuki Kitano, Yasuji Ryu, Aki Nakanami, Tetsutaro Yahata, Hiroyuki Tsuchiya
In patients with conjoined nerve roots, hemilaminectomy with sufficient exposure of the intervertebral foramen or lateral recess is required to prevent destabilization and ensure correct mobility of the lumbosacral spine. To the best of our knowledge, no case reports have detailed the long-term course of conjoined nerve roots after surgery. We report the case of a 51-year-old Japanese man with a conjoined
-
Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case report J. Med. Case Rep. Pub Date : 2024-03-06 Zeeshan Ullah, Ayesha Zafar, Hira Ishaq, Zainab Umar, Amir Khan, Yaseen Badar, Nizamud Din, Muhammad Fawad Khan, Pamela McCombe, Nemat Khan
Klippel–Feil syndrome is a rare congenital bone disorder characterized by an abnormal fusion of two or more cervical spine vertebrae. Individuals with Klippel–Feil syndrome exhibit diverse clinical manifestations, including skeletal irregularities, visual and hearing impairments, orofacial anomalies, and anomalies in various internal organs, such as the heart, kidneys, genitourinary system, and nervous
-
A new medical device applied in a case of acute fecal impaction with overflow diarrhea: a case report J. Med. Case Rep. Pub Date : 2024-03-06 Qin Huang, Fan Zheng, Hongxia Wang, Yong Yang, Chun Ma, Likun Zhu
Fecal impaction is a digestive system disease, that is most common in the elderly population and becomes more prevalent with increasing age. Manual removal can successfully remove the impaction in 80% of fecal impaction cases. In severe cases, endoscopy and surgery may be necessary. A 78-year-old Han Chinese man living in a nursing home was diagnosed with fecal impaction; his initial symptom was overflow
-
Successful management of massive digoxin overdose using DIGIFab and therapeutic plasma exchange: a case report J. Med. Case Rep. Pub Date : 2024-03-05 Reema M. Alhussein, Nawaf A. Alamri, Hussain M. Alhashem, Mohammed I. Alarifi, Bader Alyahya
Despite the efficacy and safety of DIGIFab, it is relatively expensive and has limited availability. In addition, alternative interventions, such as therapeutic plasma exchange, may need to be considered in massive digoxin overdoses. Although few case reports describe its efficacy. We report a case of a 17-year-old white male patient brought by family members to our emergency department in Riyadh,
-
Pediatric malignant pheochromocytoma with atypical presentation as vision changes, lung metastasis, and recurrence: a case report J. Med. Case Rep. Pub Date : 2024-03-05 Kaijun Zhang, Penghui Yang, Mi Li, Ping Xiang, Zhenli Cheng, Xue Zhou
This case report documents a case of malignant pheochromocytoma manifested as vision changes with lung metastasis and recurrence. A 10-year-old Han Chinese girl presented with vision changes and was eventually diagnosed with pheochromocytoma by contrast-enhanced computed tomography, urine vanillylmandelic acid. After medication for hypertension and surgery, clinical symptoms disappeared. Malignant
-
Peutz–Jeghers syndrome with polyps in the stomach, duodenum, and small and large intestine: a case report J. Med. Case Rep. Pub Date : 2024-03-05 Zaryab Ali Shah, Muhammad Zeb, Muhammad Ilyas, Hasnain Hamid, Komal Fatima, Maria Batool, Muhammad Abbas
Peutz–Jeghers syndrome is a rare hereditary condition characterized by gastrointestinal polyps and pigmented oral lesions. The case contributes to a deeper understanding of Peutz–Jeghers syndrome and underscores the significance of interdisciplinary collaboration for accurate diagnosis and tailored therapeutic strategies. We present a case of a 15-year-old Afghan female patient with multiple polyps
-
Surgical repair of tetralogy of Fallot in a 78-year-old woman: a case report J. Med. Case Rep. Pub Date : 2024-03-04 Yuzo Katayama, Sho Isobe, Tsukasa Ozawa, Takeshiro Fujii
Tetralogy of Fallot is a congenital heart disease mostly diagnosed and treated in early childhood. However, there are some adult cases receiving treatment. We describe a 78-year-old Japanese woman who presented with severely hypertrophic right ventricle, ventricular septum defect, overriding aorta, and severe infundibular stenosis in the right ventricular outflow tract. As hypoxemia was mild and daily
-
Sinonasal adenocarcinoma presented as a giant anterior cranial fossa mass: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-03-04 Endris Hussen Ali, Mulualem Wendafrash Mengesha
Intestinal adenocarcinoma accounts for less than 0.1–4% of all malignancies in the region. It is common among woodworkers and leather workers. Sinonasal adenocarcinoma usually arises from the ethmoid sinus (40%) or nasal cavity (25%). Extension to nearby structures is common, but intracranial spread is very rare. These tumors are usually treated with surgery, with a reported 5-year survival rate of
-
Features of biliary tract diseases in ketamine abusers: a systematic review of case reports J. Med. Case Rep. Pub Date : 2024-03-03 Alireza Teymouri, Hadis Nasoori, Maryamsadat Fakheri, Aref Nasiri
Anesthesiologists prefer ketamine for certain surgeries due to its effectiveness as a non-competitive inhibitor of the N-methyl-D-aspartate receptor in the brain. Recently, this agent has also shown promise as an antidepressant. However, ketamine can cause hallucinogenic effects and is sometimes abused as an illicit drug. Ketamine abuse has been associated with liver and bile duct complications. This
-
Inguinal endometriosis: a case series and review of the literature J. Med. Case Rep. Pub Date : 2024-03-02 Ameneh Haghgoo, Ali Faegh, Seyyed Reza Saadat Mostafavi, Hamid Reza Zamani, Mehran Ghahremani
Inguinal endometriosis is one of the most common forms of endometriosis. The present study introduces 8 cases of inguinal endometriosis and discusses probable theories of inguinal endometriosis by reviewing the literature. 8 Iranian cases of inguinal endometriosis with a mean age of 36 years were presented. Catamenial groin pain and swelling were the most common complications. Also, patients usually
-
Human herpesvirus-6 infection in a critically ill and immunocompetent patient: a case report J. Med. Case Rep. Pub Date : 2024-03-01 Xin Tian Chia, Hai Liang Marc Wong, Jia Shen Loh
Human herpesvirus-6 is a rare infection in an immunocompetent adult. In existing literature, there is a dearth of knowledge that mainly exists as case reports and case series. In this case report, we described a 29-year-old female of Myanmarese descent patient from Myanmar who presented with altered mental status and non-specific respiratory and gastrointestinal symptoms. She was initially treated
-
Scleritis following intravitreal brolucizumab injection: a case series J. Med. Case Rep. Pub Date : 2024-02-29 Takuya Takayama, Satoru Inoda, Hidenori Takahashi, Rika Tsukii, Hana Yoshida, Yuka Kasuya, Kosuke Nagaoka, Ryota Takahashi, Yusuke Arai, Hidetoshi Kawashima
This study reports the first cases of scleritis following intravitreal brolucizumab (IVBr) injection for nAMD, emphasizing the need to be aware of the possibility of scleritis following IVBr injections. Case 1. A 74-year-old Japanese man with nAMD complained of conjunctivitis and decreased vision in the right eye 8 days after his eighth IVBr injection. Examination revealed scleritis without anterior
-
Successful microvascular surgery in patients with thrombophilia in head and neck surgery: a case series J. Med. Case Rep. Pub Date : 2024-02-28 Julian Faber, Frank Schuster, Stefan Hartmann, Roman C. Brands, Andreas Fuchs, Anton Straub, Markus Fischer, Urs Müller-Richter, Christian Linz
In this case series, a perioperative anticoagulation protocol for microvascular head and neck surgery in patients with thrombophilia is presented. Microvascular free-flap surgery is a standard procedure in head and neck surgery with high success rates. Nevertheless, flap loss—which is most often caused by thrombosis—can occur and has far-reaching consequences, such as functional impairment, prolonged
-
IgG4 disease with multiorgan involvement: a case report J. Med. Case Rep. Pub Date : 2024-02-28 M. N. Vidanapathirana, D. Wijayaratne
IgG4-related disease (IgG4RD) is a rare fibroinflammatory disease with multiorgan involvement. It presents insidiously over several years and can be a diagnostic enigma. Delays in diagnosis occur due to failure to consider IgG4 as a differential diagnosis, atypical presentations, and an insidious clinical course. We report the case of a 70-year-old Sri Lankan man with pulmonary, renal, and neurological
-
Neonatal pyocele originating from a urinary tract infection: a case report J. Med. Case Rep. Pub Date : 2024-02-28 Zahra Jamali, Mohammad Shafie’ei, Najmeh Soltani Nejad
The origins of pyocele are primarily idiopathic, with reports suggesting the spread from intraperitoneal or hematogenous infection. However, we found no information in the literature regarding the pathogen’s spread from the urinary tract. We report here a case of a 23-day-old term Iranian boy (Fars ethnicity) with complaints of new-onset fever, irritability, poor feeding, right hemiscrotal erythema
-
Lessons from an elderly patient with pulmonary embolism caused by protein S deficiency: a case report J. Med. Case Rep. Pub Date : 2024-02-28 Liu Qiang, Li Hong, Shen Min, Wang Hongping, Chen Xian, Li Tianlang
Lower limb deep vein thrombosis (DVT) concurrent with pulmonary embolism (PE) is perilous, particularly in the elderly, exhibiting heterogeneity with thrombophilia mutations. Tailored treatment is essential, yet sudden deaths complicate causative factor elucidation. This report emphasizes genetic testing necessity in PE patients with thrombophilia indicators, facilitating cause identification, personalized
-
Testicular mesothelioma disguised as hydrocele: a case report J. Med. Case Rep. Pub Date : 2024-02-27 Tanya Nazar, Anupama Gopalakrishnabhaktan, Fatema Ali Asgar Tashrifwala, Aroma Sathish, Tirth Dave
Testicular tumors have many different manifestations. The majority of these cases are presented as an incidental finding during hydrocelectomy. Malignant mesotheliomas are uncommon tumours that can arise from the coelomic epithelium of the pleura, peritoneum, pericardium, and tunica vaginalis. We present a 51-year-old South Asian (Indian) male patient with a rare case of mesothelioma, presenting with
-
Azathioprine and hydroxychloroquine overdose in Sjögren’s syndrome patient with hypocalcemia: a case report J. Med. Case Rep. Pub Date : 2024-02-27 Alireza Kooshki, Omid Mehrpour, Samaneh Nakhaee
Hydroxychloroquine and azathioprine have been routinely used to control and treat primary and secondary Sjögren’s syndrome, which potentially triggered some overdoses by these drugs. Toxicity from hydroxychloroquine and azathioprine manifests in the form of cardiac conduction abnormalities, nausea, vomiting, and muscle weakness. Recognizing these unique drug overdoses and management of these toxicities
-
Tacrolimus-induced cholestatic hepatotoxicity after renal transplantation: a case report J. Med. Case Rep. Pub Date : 2024-02-26 Fatemeh Pourrezagholi, Hossein Amini, Omid Moradi, Shadi Ziaie
In this manuscript, we report a case of tacrolimus-associated hepatotoxicity in a kidney transplant recipient. In this case report, a 56 years old Arab male patient who received a kidney transplant presented with icterus, weakness, and lethargy two weeks after transplantation and tacrolimus initiation. In laboratory analysis hyperbilirubinemia and a rise in hepatic enzymes were observed. All possible
-
Elbow calcific tendinosis initially detected by ultrasonography: a case report J. Med. Case Rep. Pub Date : 2024-02-26 Masih Rikhtehgar, Yasaman Sharifi, Farid Najd Mazaher, Neda Azarpey
Calcific tendinosis is a common condition caused by the deposition of hydroxyapatite crystals within the tendons that can impact any tendinous insertion. In this situation, ultrasound (US) may be a viable imaging modality in addition to radiography. A 56-year-old Iranian male presented with left elbow pain. US evaluation at the lump site revealed a subcutaneous lipoma. Ultrasonography showed a thickened
-
Metastasis of cervical cancer indicated by elevation of serum CA125 produced by mediastinal lymph nodes: a case report J. Med. Case Rep. Pub Date : 2024-02-25 Ken-ichi Honda, Masato Miyama, Yuko Nishii, Reiko Tasaka, Yusuke Nakano, Naohiko Umesaki, Takeshi Fukuda, Tomoyuki Ichimura, Tomoyo Yasui, Toshiyuki Sumi
In patient assessment for recurrence of neoplasia, a biomarker that shows an elevated serum value before the first treatment is a candidate for follow-up examination. The biomarker squamous cell carcinoma antigen is usually utilized for follow-up of squamous cell cancer of the cervix. We herein report a 30-year-old Japanese woman of postoperative metastasis of cervical squamous cell cancer to the mediastinal
-
A pregnant woman with long-standing, retained intraabdominal glass shards who gave birth to a live infant with no complications: a case report J. Med. Case Rep. Pub Date : 2024-02-25 Kenta Inoue, Shinichiro Yabe, Soichiro Kashiwabara, Yukiko Itaya, Sumiko Era, Akihiko Kikuchi, Yasushi Takai
Most cases of traumatic injury during pregnancy involve blunt trauma, with penetrating trauma being uncommonly rare. In glass shard injuries, fragments often penetrate deeply, and multiple injuries may occur simultaneously; attention must be paid to the possibility of organ injury from the residual fragments. However, no case of this occurring during pregnancy has been reported yet. We present the
-
Primary thyroid lymphoma: a case series J. Med. Case Rep. Pub Date : 2024-02-24 Saida Sakhri, Ines Zemni, Mohamed Ali Ayadi, Salma Kamoun, Riadh Chargui, Tarek Ben Dhiab
Primary Thyroid Lymphoma (PTL) is defined as lymphoma involving the thyroid gland alone or the thyroid gland and adjacent neck lymph nodes without contiguous spread or distant metastases at the time of diagnosis. Most thyroid lymphomas are B cell lymphomas, and 98% of all PTL cases are non-Hodgkin’s lymphoma. It is a rare disease accounting for around 5% of the thyroid neoplasms and 2% of extranodal
-
Acute fatal ventricular arrhythmia induced by severe hyperkalemia in a toddler with decompensated methylmalonic acidemia J. Med. Case Rep. Pub Date : 2024-02-24 Zahra Hakimzadeh, Abolfazl Gilani, Parsa Yousefichaijan, Roham Sarmadian
Methylmalonic acidemia is a very rare genetic metabolic disease. Patients with isolated methylmalonic acidemia typically present with acute alterations of consciousness, failure to thrive, anorexia, vomiting, respiratory distress, and muscular hypotonia. Despite the evidence-based management, affected individuals experience significant morbidity and mortality. Hyperkalemia is one of the unusual complications
-
Sustained control of recalcitrant chronic spontaneous urticaria after initiation of inflammatory airway diseases treatment: two case reports J. Med. Case Rep. Pub Date : 2024-02-23 Doanh Nguyen, Philip Deitiker
Current classification of chronic urticaria is primarily based on clinical presentation of skin manifestations. Hence, therapeutic treatment is primarily aimed locally for immediate symptom relief. We reason that limiting therapeutic strategies to the skin pathology might be inadequate since cellular activation and inflammation might be triggered remotely. In this series two patients had exhausted
-
Nintedanib in systemic sclerosis treatment: a case report J. Med. Case Rep. Pub Date : 2024-02-23 Maysoun Kudsi, Raghad Tarcha, Naram Khalayli
Nintedanib was approved for the treatment of scleroderma and scleroderma-related interstitial lung disease, as it decrease the forced expiratory volume. A 48-year-old Asian female patient with systemic scleroderma 6 years ago developed breathlessness, nausea, heart palpation, and sudden severe occipital headache over the preceding week. She was receiving aspirin 81 mg/day and amlodipine 5 mg/day. Her
-
Ileo-ileal knot causing acute gangrenous small bowel obstruction: a case report J. Med. Case Rep. Pub Date : 2024-02-23 Yohannis Derbew Molla, Melese Birara Mequanint, Solomon Hailesilassie Bisrat, Gebrehiwot Aderaw Workneh, Hirut Tesfahun Alemu
Ileo-ileal knotting is a very rare cause of small bowel obstruction, and only a few reports have been published. Small bowel obstruction (SBO) is one of the most common emergency surgical conditions that require urgent evaluation and treatment and is one of the leading causes of emergency surgical admission. There are many causes of SBO that are known in general surgical practice, and these causes
-
Importance of cerebral angiography in the evaluation of delayed carotid stent thrombosis: a case report J. Med. Case Rep. Pub Date : 2024-02-22 Zaki Masoud, Juan Felipe Daza-Ovalle, Charles Esenwa
While noninvasive imaging is typically used during the initial assessment of carotid artery disease, digital subtraction angiography remains the gold standard for evaluating carotid stent thrombosis and stenosis (Krawisz in Cardiol Clin 39:539–549, 2021). This case highlights the importance of digital subtraction angiography for assessing carotid artery stent patency in place of non-invasive imaging
-
Pembrolizumab-induced myocarditis with complete atrioventricular block and concomitant myositis in a metastatic bladder cancer patient: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-02-22 R. Saad, A. Ghaddar, R. M. Zeenny
The cardiovascular system is among the least systems affected by immune-related adverse events. We report a rare life-threatening case of pembrolizumab-induced myocarditis with complete atrioventricular block and concomitant myositis in a metastatic bladder cancer patient. An 82-year-old Caucasian female with invasive urothelial carcinoma, started on first-line pembrolizumab, was admitted four days
-
Myoid gonadal stromal tumor of the testis—the novel subtype of testicular gonadal stromal tumors: a case report and review of the literature J. Med. Case Rep. Pub Date : 2024-02-22 Klaus-Peter Dieckmann, Lars Tharun, Markus Angerer, Alexander Harms, Christian Wülfing
Sex cord gonadal stromal tumors compose less than 10% of all testicular neoplasms and consist of a variety of histological subtypes. In 2016, the World Health Organization introduced a novel subtype, the myoid gonadal stromal tumor, that consists of spindle-shaped cells with immunohistologic features of muscle cells. Only few cases have been reported to date. Due to its rarity and owing to its only
-
Percutaneous pulmonary valve implantation in a patient with congenitally corrected transposition of the great arteries: a case report J. Med. Case Rep. Pub Date : 2024-02-21 Michal Kapalka, Michal Galeczka, Michal Krawiec, Roland Fiszer
Percutaneous pulmonary valve implantation has become an attractive method of dysfunctional right ventricle outflow tract treatment. We describe a unique case of a 20-year-old Caucasian male patient with a complex cyanotic heart defect, namely pulmonary atresia, with congenitally corrected transposition of the great arteries and ventricular septal defect after Rastelli-like surgery at the age of 5 years
-
A therapeutic challenge relating to the association of orthostatic hypotension and supine hypertension in a patient with cardiac autonomic neuropathy: a case report J. Med. Case Rep. Pub Date : 2024-02-20 Jama Dounia, Haless Kamal, Selmaoui Marouane, Haboub Meryem, Habbal Rachida, Drighil Abdenasser, Azzouzi Leila
Cardiac autonomic neuropathy is a highly prevalent pathology in the diabetic population, and is the leading cause of death in this population. Orthostatic hypotension is the main clinical manifestation of the disease. In some patients, this orthostatic hypotension is associated with supine hypertension, posing a therapeutic challenge since treatment of one entity may aggravate the other. The challenge
-
Acute compartment syndrome of the thigh after total knee arthroplasty: a case report J. Med. Case Rep. Pub Date : 2024-02-20 Marie Schuster, Tobias Kappenschneider, Matthias Meyer, Dominik Emanuel Holzapfel
Acute compartment syndrome of the thigh after total knee arthroplasty is a rarely described complication. After the assessment of the diagnosis, immediate surgical intervention is necessary to prevent further tissue damage. Since only a few cases have been described and because of the high complication rate, early detection is essential for ensuring patient outcomes. After total knee arthroplasty in