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Ameliorative effects of Tagetes erecta Linn. flower against desiccation stress-induced dry eye symptoms in the mice model Integr. Med. Res. (IF 3.4) Pub Date : 2024-03-11 Hyesook Lee, Hyun Hwangbo, Jin-Won Hyun, Jung-Hyun Shim, Sun-Hee Leem, Gi-Young Kim, Yung Hyun Choi
Tagetes erecta Linn, popularly known as Marigold, has various pharmacological effects. It is used as a natural food colorant, poultry feed additive, and nutritional supplement, especially for the posterior segment of the eye. However, the effect of T. erecta Linn on ocular disorders is still unknown. To investigate the effect of oral administration of ethanol extract of Linn flower (TE) in a murine
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Using the right design controls for acupuncture trials: Methodological rigor and validity in research Integr. Med. Res. (IF 3.4) Pub Date : 2024-02-17 Younbyoung Chae, Jun-Hwan Lee, Myeong Soo Lee
Acupuncture treatment can be defined as a medical procedure with an acupuncture needle at acupoints. Establishing suitable control settings is essential, based on the target elements of the acupuncture therapy. In order to properly design a clinical trial or an experiment, a control group must be established. Here, we overview the significance of the control group and its limitations in acupuncture
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Efficacy and safety of herbal medicine Gongjin-Dan and Ssanghwa-Tang in patients with chronic fatigue: A randomized, double-blind, placebo-controlled, clinical trial Integr. Med. Res. (IF 3.4) Pub Date : 2024-02-16 Jun-Yong Choi, Bom Choi, Ojin Kwon, Chang-Seob Seo, Ae-Ran Kim, Hyeun-kyoo Shin, Kibong Kim
Gongjin-dan (GJD) and Ssanghwa-tang (SHT) are herbal medicines that are widely used in Korea for treating fatigue. However, few studies have evaluated the efficacy and safety of GJD and SHT in the treatment of chronic fatigue. In this randomized, double-blind, placebo-controlled clinical trial, ninety individuals with persistent (≥6 months) chronic fatigue of unknown cause and a Fatigue Severity Scale
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Traditional, complementary, and integrative medicine and artificial intelligence: Novel opportunities in healthcare Integr. Med. Res. (IF 3.4) Pub Date : 2024-02-09 Jeremy Y. Ng, Holger Cramer, Myeong Soo Lee, David Moher
The convergence of traditional, complementary, and integrative medicine (TCIM) with artificial intelligence (AI) is a promising frontier in healthcare. TCIM is a patient-centric approach that combines conventional medicine with complementary therapies, emphasizing holistic well-being. AI can revolutionize healthcare through data-driven decision-making and personalized treatment plans. This article
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Acupuncture treatment for Hashimoto's thyroiditis: An exploratory randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2024-02-06 Shanze Wang, Chao Yang, Weimei Zeng, Hongfang Tian, Shihao Du, Jiping Zhao
Hashimoto's thyroiditis (HT) has a high incidence rate and unresolved clinical symptoms. Although Hand Yangming Meridian Penetrating Acupuncture has been used to treat thyroid diseases in China, there is no randomized controlled trial (RCT) on HT. This exploratory RCT aims to preliminarily evaluate the efficacy, safety, and feasibility of Hand Yangming Meridian Penetrating Acupuncture in the treatment
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Acupuncture for response and complete pain relief time of acute renal colic: secondary analysis of a randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2024-01-20 Xue-Zhou Wang, Cun-Zhi Liu, Li-Qiong Wang, Zhi-Cheng Qu, Ying Cao, Shi-Yan Yan, Jing-Wen Yang, Jian-Feng Tu
Background The integration of acupuncture with intramuscular injection of diclofenac sodium can expedite the onset of analgesia in treating acute renal colic caused by urolithiasis. However, it remains unclear whether acupuncture can accelerate pain relief constantly until complete remission. This study aimed to explore the extent to which acupuncture can expedite the onset time of response or complete
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Curcuma xanthorrhiza extract and xanthorrhizol ameliorate cancer-induced adipose wasting in CT26-bearing mice by regulating lipid metabolism and adipose tissue browning Integr. Med. Res. (IF 3.4) Pub Date : 2023-12-24 Haeun Kim, Dong-Woo Lee, Jae-Kwan Hwang
Background Cancer cachexia—characterized by anorexia, body weight loss, skeletal muscle atrophy, and fat loss—affects nearly 80% of cancer patients and accounts for 20% of cancer deaths. Curcuma xanthorrhiza, known as Java turmeric, and its active compound xanthorrhizol (XAN) exhibit anticancer, anti-inflammatory, and antioxidant properties. However, the ameliorative effects of C. xanthorrhiza extract
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Traditional Chinese medicine diagnostic prediction model for holistic syndrome differentiation based on deep learning Integr. Med. Res. (IF 3.4) Pub Date : 2023-12-19 Zhe Chen, Dong Zhang, Chunxiang Liu, Hui Wang, Xinyao Jin, Fengwen Yang, Junhua Zhang
Background With the development of traditional Chinese medicine (TCM) syndrome knowledge accumulation and artificial intelligence (AI), this study proposes a holistic TCM syndrome differentiation model for the classification prediction of multiple TCM syndromes based on deep learning and accelerates the construction of modern foundational TCM equipment. Methods We searched publicly available TCM guidelines
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How to understand and report heterogeneity in a meta-analysis: The difference between I-squared and prediction intervals Integr. Med. Res. (IF 3.4) Pub Date : 2023-11-28 Michael Borenstein
In any meta-analysis it is important to report not only the mean effect size but also how the effect size varies across studies. A treatment that has a moderate clinical impact in all studies is very different than a treatment where the impact is moderate on average, but in some studies is large and in others is trivial (or even harmful). A treatment that has no impact in any studies is very different
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Herbal medicine (Oryeongsan) for fluid and sodium balance in renal cortex of spontaneously hypertensive rats Integr. Med. Res. (IF 3.4) Pub Date : 2023-11-15 You Mee Ahn, Hye Yoom Kim, Dae Gill Kang, Kyung Woo Cho, Ho Sub Lee
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Deep electroacupuncture of neurogenic spots attenuates immobilization stress-induced acute hypertension in rats Integr. Med. Res. (IF 3.4) Pub Date : 2023-11-15 Cong Zhan, Han Byeol Jang, DanBi Ahn, Suchan Chang, Yeonhee Ryu, Hyung Kyu Kim, Bong Hyo Lee, Xiaowei Guan, Yu Fan, Bae Hwan Lee, Hee Young Kim
Background Our previous studies proved that neurogenic inflammatory spots (or neurogenic spots) have the same physiological features as acupuncture points and that neurogenic spot stimulation generates therapeutic effects in various animal models. However, it is unclear how deeply the neurogenic spots should be stimulated to generate therapeutic effects. Methods The effects of acupuncture at various
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Chinese herbal injections in combination with radiotherapy for advanced pancreatic cancer: A systematic review and network meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-28 Yun-Ru Chen, Ruo-Tong Zhao, Yi-Fang Xu, Yin-Jie Ma, Shao-Bo Hu, Xue-Hui Wang, Bing-Bing Fan, Yan-Ji Zhou, Yu-Bei Huang, Nicola Robinson, Jian-Ping Liu, Zhao-Lan Liu
Background Advanced pancreatic cancer (APC) is a fatal disease with limited treatment options. This study aims to evaluate the effectiveness and safety of different Chinese herbal injections (CHIs) as adjuvants for radiotherapy (RT) in APC and compare their treatment potentials using network meta-analysis. Methods We systematically searched three English and four Chinese databases for randomized controlled
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Acupuncture for endometriosis: A systematic review and meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-28 Nora Giese, Ki Kyung Kwon, Mike Armour
Background Current endometriosis treatments do not always provide symptom relief, with many using complementary approaches. This study examined the effectiveness of acupuncture on pain and quality of life in people with endometriosis. Methods Searches were conducted on Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Allied and Complementary Medicine Database (AMED) and Embase (Ovid)
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Effects of herbal medicines (Eunkyosan/Yin qiao san and Samsoeum/Shen su yin) for treating the common cold: A randomized, placebo-controlled, multicenter clinical trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-26 Kwan-Il Kim, Minna Hong, Yang-Chun Park, Beom-Joon Lee, Kitae Kim, Byoung Kab Kang, Jun-Yong Choi
Background Eunkyosan (EKS) and Samsoeum (SSE), which are called Yin qiao san and Shen su yin in Chinese, are commonly used herbal medicines for the common cold in East Asian countries. This study aimed to evaluate the effectiveness and safety of EKS and SSE for treating the common cold. Methods A randomized, patient-assessor-blind, placebo-controlled, parallel, and multicenter clinical trial was conducted
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Effects of aromatherapy on sore throat, nasal symptoms and sleep quality in adults infected with COVID-19: A randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-21 Hye-Young Kang, Hye Young Ahn, Mi-Jung Kang, Myung-Haeng Hur
Background Patients with coronavirus disease 2019 (COVID-19) usually complain of fever, cough, and sore throat. This study examined the effects of aromatherapy on sore throat, nasal symptoms, stress, fatigue, and sleep quality by administering it to adults with post-COVID-19 condition. Methods This study was conducted in a randomised controlled design. Its target population were adults who were released
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Oversimplifying the name of the 12 meridian channels Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-21 In-Seon Lee, Yeonhee Ryu, Younbyoung Chae
Abstract not available
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GV16 acupoint stimulation with bee venom reduces peripheral hypersensitivity via activation of α2 adrenoceptors in a nitroglycerin-induced migraine mouse model Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-20 Sol-Ji Kim, Ji-Hee Yeo, Seo-Yeon Yoon, Dae-Hyun Roh
Background Peripheral hypersensitivities develop in the face and hindpaws of mice with nitroglycerin (NTG)-induced migraine. We evaluated whether diluted bee venom (DBV) injections at acupoints prevented these peripheral hypersensitivities and c-Fos expression in the trigeminal nucleus caudalis (TNC). Methods NTG (10 mg/kg, intraperitoneal, i.p.) was administered every other day for nine days. DBV
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Real-world data analysis on effectiveness of integrative therapies: A practical guide to study design and data analysis using healthcare databases Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-20 Ye-Seul Lee, Yoon Jae Lee, In-Hyuk Ha
Real world data (RWD) is increasingly used to investigate health outcomes and treatment efficacy in the field of integrative medicine. Due to the fact that the majority of RWDs are not intended for research, their secondary use in research necessitates complex study designs to account for bias and confounding. To conduct a robust analysis of RWD in integrative medicine, a comprehensive study design
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Saposhnikovia divaricata root and its major components ameliorate inflammation and altered gut microbial diversity and compositions in DSS-induced colitis Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-19 Saruul Erdenebileg, Yang-Ju Son, Myungsuk Kim, Sarangerel Oidovsambuu, Kwang Hyun Cha, Jaeyoung Kwon, Da Seul Jung, Chu Won Nho
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Acupuncture for ventilator-dependent patients at a hospital-based respiratory care center: A randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-10-17 Jia-Ming Chen, Wan-Li Chiang, Bin-Chuan Ji, Ruei-Jhe Jhang, Pei-Hsin Chen, Ya-Lun Li, Che-Ju Chang, Sung-Yen Huang, Tsung-Chieh Lee, Chia-Yun Chen, Ching-Hsiung Lin, Sheng-Hao Lin
Background In intensive care units, mechanical ventilation is an important therapy to help patients with dyspnea. However, long-term ventilator dependence would consume huge medical resources and increase the risk of morbidity and mortality. The aim of the study was to examine the efficacy of the acupuncture combined with western medical care on ventilator parameters in ventilator-dependent patients
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Dietary and herbal supplement consumer health information for pain: A cross-sectional survey and quality assessment of online content Integr. Med. Res. (IF 3.4) Pub Date : 2023-09-28 Jeremy Y Ng, Sahar Popal, Sathurthika Selvanayagam
Background Patients are increasingly utilizing the internet to learn about dietary and herbal supplements (DHSs) for various diseases/conditions, including pain management. Online health information has been found to be inconsistent and of poor quality in prior studies, which may have detrimental effects on patient health. This study assessed the quality of online DHSs consumer health information for
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What is integrative medicine? Establishing the decision criteria for an operational definition of integrative medicine for general practice health services research in Australia Integr. Med. Res. (IF 3.4) Pub Date : 2023-09-24 Jennifer Hunter, Joanna E. Harnett, Wai-Jo Jocelin Chan, Marie Pirotta
Background Operational definitions outline how a conceptual definition will be measured for consistent, reproducible data collection and analysis. This article reports the decision criteria that will be used for an operational definition of integrative medicine (IM) in a secondary analysis of an Australian national survey of general practitioner activity. Methods A multidisciplinary team applied an
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Clinical effectiveness of mindfulness-based music therapy on improving emotional regulation in blind older women: A randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-08-26 Sunny H.W. Chan, Meryl Y.C. Cheung, Armstrong T.S. Chiu, Mimi H.T. Leung, Michael C.C. Kuo, Donald Y.C. Yip, Carole C.Y. Hui, Sally W.I. Kam, King Yeung, Doreen S.P. Mui, Shu-Mei Wang, Calvin C.K. Yip
Background This study aimed to investigate clinical effectiveness of a structured eight-week mindfulness-based music therapy (MBMT) program on improving mood regulation in older women with blindness. This investigation compared a MBMT group with a mindfulness intervention (MI) group and a control group. Methods Ninety-two older females with blindness from a residential setting in Hong Kong were recruited
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Economic evaluation of acupuncture as an adjunctive treatment with usual care for mild-to-moderate knee osteoarthritis: A Markov model-based analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-08-11 Eunhye Hyun, Byung-Cheul Shin, NamKwen Kim, Byungmook Lim
Background Collaborative care (CC), in which acupuncture is combined with usual care (UC), improves clinical outcomes and increases costs in knee osteoarthritis (KOA). We evaluated the economic feasibility of CC for Korean female patients with mild-to-moderate KOA by using a cost-effectiveness approach. Methods Two alternatives for KOA (1. UC as a comparator; and 2. CC as an intervention) were defined
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Three aspects of acupuncture-related adverse events: Issues around the reporting of acupuncture-related adverse events Integr. Med. Res. (IF 3.4) Pub Date : 2023-08-06 Tae-Hun Kim, Stephen Birch, Terje Alraek, Myeong Soo Lee
Abstract not available
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The association between acupuncture therapy and the risk of reduced pressure ulcers in dementia patients: A retrospective matched cohort study Integr. Med. Res. (IF 3.4) Pub Date : 2023-08-06 Chia-Yu Huang, Mei-Yao Wu, Ming-Cheng Huang, Teng-Shun Yu, Hung-Rong Yen
Background The pressure ulcer is a complication developed from dementia. The aim of this study is to study the association between the development of pressure ulcers and the use of acupuncture therapy in patients with dementia. Methods We performed a retrospective 1:1 propensity score-matched cohort study to investigate the association between acupuncture therapy and the risk of pressure ulcers in
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AI Chat bot - ChatGPT-4: A new opportunity and challenges in complementary and alternative medicine (CAM) Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-29 Tae-Hun Kim, Jung Won Kang, Myeong Soo Lee
Abstract not available
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The Brief History of Complementary, Alternative, and Integrative Medicine Terminology and the Development and Creation of an Operational Definition Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-28 Jeremy Y. Ng, Tushar Dhawan, Renee-Gabrielle Fajardo, Hooriya A. Masood, Samira Sunderji, L. Susan Wieland, David Moher
The definition of complementary, alternative, and integrative medicine (CAIM) remains dynamic and complex despite a steady increase in the popularity/usage of CAIM therapies across the globe. A lack of consistency in how these terms are defined remains a challenge for researchers, clinicians, and national and international organizations (e.g., World Health Organization, National Center for Complementary
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The impact of yoga on stress, metabolic parameters, and cognition of Indian adolescents: Cluster randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-28 Harish Ranjani, Narayanaswamy Jagannathan, Tina Rawal, Radhakrishnan Vinothkumar, Nikhil Tandon, Jayaram Vidyulatha, Viswanathan Mohan, Yashdeep Gupta, Ranjit Mohan Anjana
Background This project aimed to assess the impact of yoga on stress, metabolic parameters and cognition (attention & concentration) in adolescents, aged 13–15 years from public and private schools in two cities (Chennai and New Delhi) in India. Methods The study recruited 2000 adolescents from 24 schools in a cluster randomized controlled trial design. The yoga group participants underwent 17 yoga
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Acupuncture-related therapies for protracted opioid abstinence syndrome:A systematic review and meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-28 Lu Ding, Cui Li, Peiming Zhang, Chen Chen, Jie Zhan, Jinchun Zeng, Liming Lu
Background An increasing amount of clinical evidence of acupuncture's effect on protracted opioid abstinence syndrome (POAS) has emerged in recent years. The aim of this study was to evaluating the evidence of efficacy of acupuncture for POAS. clinical and scientific research work. Methods Four English-language databases (PubMed, Medline, Embase, Cochrane Libraries) and three Chinese-language databases
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Clinical effectiveness of decoction form of herbal medicine in primary care treatment of allergic rhinitis: A retrospective cohort study Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-13 Mi Ju Son, Sungha Kim, Young-Eun Kim, Bo-Young Kim, Chang-Sub Yeum, Jong Cheol Lee, Jae Hoon Cha, Soonsik Kang, Ching Hao Chang, Seokho Son
Background The decoction form of herbal medicine (D-HM) is mainly prescribed to patients with allergic rhinitis (AR) in Korean Medicine (KM) clinics in the Republic of Korea; however, it is difficult to conduct clinical trials of D-HM due to regulatory issues. This study investigated the clinical safety and effectiveness of D-HM combination therapy for the treatment of AR by analyzing the AR outpatient
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Moxibustion for medical personnel with negative emotion and insomnia during COVID-19 pandemic: A randomized, controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-13 Xiying Li, Xiaojuan Li, Xian Wang, Xuan Yin, Shanshan Li, Junyi Wu, Xiumei Ren, Wei Zhang, Yiqun Mi, Shifen Xu
Background We conducted this randomized controlled trial (RCT) to evaluate the effectiveness and safety of moxibustion at Sanyinjiao (SP6) acupoint for treatment of negative mood and sleep quality in healthcare workers during the 2019 coronavirus disease (COVID-19). Methods A total of 180 participants were divided in a 1:1 ratio into two groups, the treatment group (for moxibustion) and the control
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Complementary, alternative, and integrative medicine-specific COVID-19 misinformation on social media: A scoping review Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-13 Jeremy Y. Ng, Shawn Liu, Ishana Maini, Will Pereira, Holger Cramer, David Moher
Background The sharing of health-related information has become increasingly popular on social media. Unregulated information sharing has led to the spread of misinformation, especially regarding complementary, alternative, and integrative medicine (CAIM). This scoping review synthesized evidence surrounding the spread of CAIM-related misinformation on social media during the COVID-19 pandemic. Methods
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Acupuncture as an alternative or in addition to conventional treatment for chronic non-specific low back pain: Systematic review and meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-07 Carlo Maria Giovanardi, Marien Gonzalez-Lorenzo, Alessandra Poini, Eleonora Marchi, Antonio Culcasi, Francesco Ursini, Cesare Faldini, Alberto Di Martino, Umberto Mazzanti, Emanuela Campesato, Annunzio Matrà, Sabina Cevoli, Maria Grazia Benedetti
Background Conventional therapies (CTs), pharmacological (PH) and non–pharmacological (NPH), do not always achieve benefits in the treatment of chronic low back pain (CLBP). We assessed efficacy and safety of acupuncture for CLBP as alternative or addition to CT. Methods We included randomised controlled trials (RCTs) comparing acupuncture alone or in combination with CT to CT. We searched Medline
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Thread-embedding acupuncture may improve symptom resolution in patients with gastroesophageal reflux disease: A randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-07-07 Dieu-Thuong Thi Trinh, An Hoa Tran, Minh-Man Pham Bui, Nguyen Lam Vuong
Background Various traditional medicine treatments have been investigated to treat GERD. Among those, thread-embedding acupuncture (TEA) has the advantage that patients need to undergo the procedure infrequently; however, its efficacy is unclear. This study evaluated the efficacy of TEA in treating GERD. Methods A randomized controlled trial was conducted with 66 participants with GERD: 33 received
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Curcumin, inflammation, and neurological disorders: How are they linked? Integr. Med. Res. (IF 3.4) Pub Date : 2023-06-25 Prachi Garodia, Mangala Hegde, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal
Background Despite the extensive research in recent years, the current treatment modalities for neurological disorders are suboptimal. Curcumin, a polyphenol found in Curcuma genus, has been shown to mitigate the pathophysiology and clinical sequalae involved in neuroinflammation and neurodegenerative diseases. Methods We searched PubMed database for relevant publications on curcumin and its uses in
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Acupuncture treatment for functional gastrointestinal disorders: Identification of major acupoints using network analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-06-23 Heeyoung Moon, Yeonhee Ryu, In-Seon Lee, Younbyoung Chae
Background Using network analysis, we sought to determine the acupoints most commonly used to treat functional gastrointestinal disorders (FGIDs), particularly functional dyspepsia (FD) and irritable bowel syndrome (IBS). Methods To explore the acupoint patterns used for FGID, data on acupoint combinations for FD and IBS were gathered from systematic reviews. Network analysis was used to determine
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Patient preferences and shared decision making for the traditional Chinese medicine treatment of lung cancer: A discrete choice experiment study Integr. Med. Res. (IF 3.4) Pub Date : 2023-06-22 Yue Teng, Yan Wei, Yingyao Chen, Juntao Yan, Shimeng Liu, Fuming Li, Shiyi Bao, Yanfeng Ren, Liu Liu, Yi Yang
Background Traditional Chinese Medicine (TCM), integrating patient preferences into decision-making process, has been widely used in the multimodality therapy of lung cancer. This study aimed to estimate patient preferences for treatment and shared decision-making (SDM) modes concerning inpatient TCM treatment of lung cancer in Shanghai in order to provide a basis for clinical decision-making process
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Efficacy and safety of herbal medicine (Binafuxi granules) for the common cold with fever: A multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-05-19 Xuemei Liu, Jie Min, Bin She, Yan Chen, Jun Li, Lei Huang, Ju Chen, Ai Luo, Mei Yang, Ting Li, Yanqing Wu, Daohong Chen, Hongli Zhong, Wei Liu, Bing Mao, Hongli Jiang
Background Binafuxi granules are a traditional Uighur medicine (TUM) for treating the common cold with fever. However, high-quality clinical studies supporting its efficacy and safety are lacking. Methods In this multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial, patients with common cold and fever were randomly assigned to a high-dose group, low-dose group, and placebo
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ACURATE: A guide for reporting sham controls in trials using acupuncture Integr. Med. Res. (IF 3.4) Pub Date : 2023-05-13 Ye-Seul Lee, Song-Yi Kim, Hyangsook Lee, Younbyoung Chae, Myeong Soo Lee
This paper presents the Acupuncture Controls gUideline for Reporting humAn Trials and Experiments (ACURATE) checklist, an extension of The Consolidated Standards for Reporting of Trials (CONSORT) and to be used along with STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) when both real and sham acupuncture needles are used in the study. This checklist focuses on a clear
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Potential role of acupuncture in the treatment of Parkinson's disease: A narrative review Integr. Med. Res. (IF 3.4) Pub Date : 2023-05-11 Jaeyoung Park, Ju-Young Oh, Hi-Joon Park
Background The prevalence of Parkinson’s disease (PD) has grown rapidly compared to that of other neurological disorders. Acupuncture has been used to address the complex symptoms of PD. Recently, similarities in the mechanisms of action between acupuncture and neuromodulation have received considerable attention. This review aims to summarize the evidence regarding these similarities to suggest potential
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Misreport of burns as a result of ‘coining’, Gua sha; inherent harms from publication and ongoing citation of false facts Integr. Med. Res. (IF 3.4) Pub Date : 2023-05-04 Arya Nielsen, Marsha Handel, Jennifer A. M. Stone, Myeong Soo Lee
Abstract not available
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Developing TCM clinical practice guidelines: A comparison between traditional Chinese medicine and western medicine Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-25 Xuan Yu, Shouyuan Wu, Juanjuan Zhang, Yue Hu, Meng Luo, Hongmei Zhao, Xuping Song, Yaolong Chen, Xiaohui Wang
Clinical practice guidelines in Traditional Chinese Medicine (CPG-TCM) is the recommendation that aims to provide the best service to users by identifying and summarizing the rules of prevention, diagnosis, treatment, rehabilitation, and regression of diseases based on systematic reviews of evidence and balancing the advantages and disadvantages of different interventions for clinical questions of
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Attenuation of skeletal muscle atrophy via acupuncture, electro-acupuncture, and electrical stimulation Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-23 T. Brock Symons, Jinho Park, Joo Hyun Kim, Eun Hye Kwon, Jesse Delacruz, Junghoon Lee, Yoonjung Park, Eunhee Chung, Sukho Lee
Background Accelerated skeletal muscle wasting is a shared trait among many pathologies and aging. Acupuncture has been used as a therapeutic intervention to control pain; however, little is known about its effects on skeletal muscle atrophy and function. The study's purpose was to compare the effects of acupuncture, electro-acupuncture, and electrical stimulation on cast-induced skeletal muscle atrophy
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Beneficial effect of Gyejibokryeong-hwan on climacteric syndrome with blood stasis pattern: A randomized, double-blinded, placebo-controlled clinical pilot trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-21 Kyungsun Han, Jeong-Eun Yoo, Jung-Eun Kim, Ojin Kwon, Ae-Ran Kim, Hyo-Ju Park, So-Young Jung, Mikyung Kim, Changsop Yang, Jung-Hyo Cho, Jun-Hwan Lee
Background Gyejibokryeong-hwan (GBH), a herbal mixture that is widely used for climacteric syndrome, is studied for its efficacy; however, no study evaluated the GBH indication, which is a blood-stasis pattern based on traditional Chinese medicine theory. Methods This is a randomized, double-blinded, placebo-controlled clinical pilot trial. Fifty subjects with climacteric syndrome were recruited and
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Effectiveness of Chinese medicine formula Huashibaidu granule on mild COVID-19 patients: A prospective, non-randomized, controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-21 Bowu Chen, Yan Xue, Hua Jing, Xiaodong Wang, Peimin Zhu, Weiwei Hao, Man Li, Yueqiu Gao
Background The effectiveness and safety of Huashibaidu granule (HSBD) in treating mild Corona Virus Disease 2019 (COVID-19) patients infected with SARS-CoV-2 remain to be identified. We aimed to evaluate the effectiveness of HSBD in mild COVID-19 patients. Methods A prospective, non-randomized, controlled study in mild COVID-19 patients was conducted in Shanghai, from April 8 to May 6, 2022. The enrolled
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Effect and mechanism of Magnolia officinalis pharmacopuncture for treating localized fat via network pharmacology and experimental study Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-07 Won Jun Choi, Mi Hye Kim, Nayoung Park, Jae Yoon Chung, Sang Jun Park, Woong Mo Yang
Background Recently, for various reasons, the need for non-invasive treatment for localized fat has emerged. This study confirmed whether Magnolia officinalis (MO) pharmacopuncture reduces localized fat by promoting lipolysis and inhibiting adipogenesis. Methods The network was built using genes related to the active compound of MO and the mode of action of MO was predicted by the functional enrichment
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Comparative effectiveness of Chinese herbal injections treating for rotavirus enteritis in children: A systematic review and Bayesian network meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-03 Li-Qing Niu, Lu Xiao, Qiu-Han Cai, Yu-Yi Wu, Si-Yuan Hu, Sheng-Xuan Guo, Yu-Ling Tian, Qiu-Rong Wang
Background Rotavirus enteritis (RVE) accounts for 37% of all death in children (<5 years) with diarrhea. Chinese herbal injections (CHIs) have drawn more attention from practitioners because of the valid effects for RVE. However, the most beneficial one has not yet been determined. Methods Eight databases were searched from their inception up to September 3rd, 2022. The primary outcome was clinical
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Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-03 Heng Weng, Qing Wang, Ran Ye, Yamei Bai, Hui Yang, Guihua Xu, Qiuqin Wang
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Frankincense ameliorates endometriosis via inducing apoptosis and reducing adhesion Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-03 Min Kyoung Cho, Jung-Sook Jin, Yunju Jo, Jung Ho Han, Su Shin, Sung-Jin Bae, Dongryeol Ryu, Jongkil Joo, Jang-Kyung Park, Ki-Tae Ha
Background Frankincense, a resin derived from trees of the Boswellia genus, has been used as an incense and a type of herbal medicine for treating inflammatory diseases such arthritis, chronic bowel illness, and asthma. While endometriosis is a well-known inflammatory gynecological illness caused by the ectopic attachment and development of uterine tissue over the menstrual cycle, the impact of frankincense
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World Health Organization survey on the level of integration of traditional Chinese medicine in Chinese health system rehabilitation services Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-03 Lei Fang, Ran-ran Zhu, Zhen Sang, Xiao-ting Xu, Lin-yun Zheng, Yanwei Xiang, Chaoyang Guo, Zhenrui Li, Stéphane Alexandre Espinosa, Qi Zhang, Chunlei Shan
Background To meet the growing global demand for rehabilitation services, the World Health Organization (WHO) launched Rehabilitation 2030. This study was commissioned by the WHO to investigate the integration degree of traditional Chinese medicine (TCM) in Chinese health system rehabilitation services and the demand for TCM rehabilitation in China. Methods Twenty TCM rehabilitation experts and relevant
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Impact of ejaculation upon effect of acupuncture on chronic prostatitis/chronic pelvic pain syndrome: Secondary analysis of a randomized controlled trial Integr. Med. Res. (IF 3.4) Pub Date : 2023-04-03 Lili Zhu, Jiufei Fang, Yuanjie Sun, Min Yang, Hao Yao, Zhishun Liu
Background Acupuncture can improve chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Ejaculation frequencies might impact the conditions of CP/CPPS. The present study aimed to explore the impact of different ejaculation frequencies on the effect of acupuncture among men with CP/CPPS. Methods This was a secondary analysis of the data from a multicenter, randomized, clinical trial. Eligible
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Efficacy of acupuncture for cardiopulmonary cerebral resuscitation: A systematic review and meta-analysis Integr. Med. Res. (IF 3.4) Pub Date : 2023-02-05 Yunlan Liu, Mengjuan Ren, Zhuoran Kuang, Xufei Luo, Huishan Li, Yikai Zhang, Wanxin Wen, Yefeng Cai, Xiaojia Ni, Yaolong Chen
Background Cerebral resuscitation is one of the main therapeutic aims in the treatment of cardiac arrest (CA) patients who experience a return of spontaneous circulation (ROSC). However, the therapeutic effects of current treatments are not ideal. The purpose of this study was to evaluate the efficacy of neurological function of acupuncture combined with conventional cardiopulmonary cerebral resuscitationthe
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Addressing cancer-related fatigue through sleep: A secondary analysis of a randomized trial comparing acupuncture and cognitive behavioral therapy for insomnia Integr. Med. Res. (IF 3.4) Pub Date : 2023-02-03 Xiaotong Li, Kevin T. Liou, Susan Chimonas, Karolina Bryl, Greta Wong, Eugenie Spiguel, Susan Q. Li, Sheila N. Garland, Ting Bao, Jun J. Mao
Background Fatigue is a troublesome symptom in cancer survivors that often results from disrupted sleep. We sought to assess whether two insomnia-focused non-pharmacological interventions are also effective for improving fatigue. Methods We analyzed data from a randomized clinical trial comparing cognitive behavioral therapy for insomnia (CBT-I) versus acupuncture for insomnia among cancer survivors