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Reorienting the Debate on Biological Individuality: Politics and Practices Acta Biotheor. (IF 1.3) Pub Date : 2024-02-28 Rose Trappes
Biological individuality is without a doubt a key concept in philosophy of biology. Questions around the individuality of organisms, species, and biological systems can be traced throughout the philosophy of biology since the discipline’s inception, not to mention the sustained attention they have received in biology and philosophy more broadly. It’s high time the topic got its own Cambridge Element
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What Influence Could the Acceptance of Visitors Cause on the Epidemic Dynamics of a Reinfectious Disease?: A Mathematical Model Acta Biotheor. (IF 1.3) Pub Date : 2024-02-25
Abstract The globalization in business and tourism becomes crucial more and more for the economical sustainability of local communities. In the presence of an epidemic outbreak, there must be such a decision on the policy by the host community as whether to accept visitors or not, the number of acceptable visitors, or the condition for acceptable visitors. Making use of an SIRI type of mathematical
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Model of Calcium Dynamics Regulating $$IP_{3}$$ , ATP and Insulin Production in a Pancreatic $$\beta$$ -Cell Acta Biotheor. (IF 1.3) Pub Date : 2024-02-09 Vaishali, Neeru Adlakha
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Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality Acta Biotheor. (IF 1.3) Pub Date : 2023-12-27 Leonardo Bich
This paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and
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Theoretical Assessment of the Impact of Water Stress on Plants Production: Case of Banana-Plantain Acta Biotheor. (IF 1.3) Pub Date : 2023-11-15 Carmelle Kabiwa Kadje, André Nana Yakam, Samuel Bowong, Gisèle Mophou
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The First Nucleic Acid Strands May Have Grown on Peptides via Primeval Reverse Translation Acta Biotheor. (IF 1.3) Pub Date : 2023-11-10 Arturo Tozzi, Marco Mazzeo
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On Pattern-Cladistic Analyses Based on Complete Plastid Genome Sequences Acta Biotheor. (IF 1.3) Pub Date : 2023-11-03 Evgeny V. Mavrodiev, Alexander Madorsky
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Interior Operators and Their Relationship to Autocatalytic Networks Acta Biotheor. (IF 1.3) Pub Date : 2023-10-27 Mike Steel
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Targeted Hypermutation as a Survival Strategy: A Theoretical Approach Acta Biotheor. (IF 1.3) Pub Date : 2023-09-05 Seymour Garte
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Assessment of the Global Variance Effective Size of Subdivided Populations, and Its Relation to Other Effective Sizes Acta Biotheor. (IF 1.3) Pub Date : 2023-07-17 Ola Hössjer, Linda Laikre, Nils Ryman
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Social Pressure from a Core Group can Cause Self-Sustained Oscillations in an Epidemic Model Acta Biotheor. (IF 1.3) Pub Date : 2023-06-22 A. P. Baccili, L. H. A. Monteiro
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The Role of Information in Evolutionary Biology Acta Biotheor. (IF 1.3) Pub Date : 2023-05-15 Thomas E. Dickins
The Modern Synthesis has received criticism for its purported gene-centrism. That criticism relies on a concept of the gene as a unit of instructional information. In this paper I discuss information concepts and endorse one, developed from Floridi, that sees information as a functional relationship between data and context. I use this concept to inspect developmental criticisms of the Modern Synthesis
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Mathematical Model of Synaptic Long-Term Potentiation as a Bistability in a Chain of Biochemical Reactions with a Positive Feedback Acta Biotheor. (IF 1.3) Pub Date : 2023-05-06 Pranas Katauskis, Feliksas Ivanauskas, Aidas Alaburda
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The Membrane Potential Has a Primary Key Equation Acta Biotheor. (IF 1.3) Pub Date : 2023-05-06 Hirohisa Tamagawa, Toi Nakahata, Ren Sugimori, Bernard Delalande, Titus Mulembo
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Sulfur is in the Air: Cyanolichen Marriages and Pollution Acta Biotheor. (IF 1.3) Pub Date : 2023-05-06 Dilantha Gunawardana, Rasika P. Wanigatunge, Jayani J. Wewalwela, Meththika Vithanage, Chandrani Wijeyaratne
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From Minerals to Simplest Living Matter: Life Origination Hydrate Theory Acta Biotheor. (IF 1.3) Pub Date : 2023-03-28 Elena A. Kadyshevich, Victor E. Ostrovskii
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Random with Respect to Fitness or External Selection? An Important but Often Overlooked Distinction Acta Biotheor. (IF 1.3) Pub Date : 2023-03-18 Jonathan Bartlett
Mutations are often described as being “random with respect to fitness.” Here we show that the experiments used to establish randomness with respect to fitness are only capable of showing that mutations are random with respect to current external selection. Current debates about whether or not mutations are directed may be at least partially resolved by making use of this distinction. Additionally
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A Gender-Selective Harvesting Strategy: Weak Allee Effects and a Non-hyperbolic Extinction Boundary Acta Biotheor. (IF 1.3) Pub Date : 2023-03-18 Eric M. Takyi, Joydeb Bhattacharyya, Rana D. Parshad
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Mathematical Model of COVID-19 Pandemic with Double Dose Vaccination Acta Biotheor. (IF 1.3) Pub Date : 2023-03-06 Olumuyiwa James Peter, Hasan S. Panigoro, Afeez Abidemi, Mayowa M. Ojo, Festus Abiodun Oguntolu
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Fast Track Treatment of Hypothyroidism with Levothyroxine: Reaching Homeostasis within Four Weeks Acta Biotheor. (IF 1.3) Pub Date : 2023-03-07 Simon L. Goede
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A Very Nice Meal with an Unsatisfying Appetizer Acta Biotheor. (IF 1.3) Pub Date : 2023-03-03 Antonella Tramacere
As an Italian from the South, I have been socialized to care a lot about cooking. Quality of the food is a fundamental starting point for a successful result; in addition, you need expertise in food preparation and the capacity to balance dishes together in a single meal, from appetizer to dessert. I find Isabella Sarto-Jackson’s book The Making and Breaking of Mind a very nice meal with good-quality
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Heuristics Facilitates the Evolution of Transitive Inference and Social Hierarchy in a Large Group Acta Biotheor. (IF 1.3) Pub Date : 2023-03-03 Kazuto Doi, Mayuko Nakamaru
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The Multi-Causal Basis of Developmental Potential Construction Acta Biotheor. (IF 1.3) Pub Date : 2023-01-30 Davide Vecchi, Gil Santos
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The Connection of the Generalized Robinson–Foulds Metric with Partial Wiener Indices Acta Biotheor. (IF 1.3) Pub Date : 2023-01-25 Damir Vukičević, Domagoj Matijević
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Model of Morphogenesis with Repelling Signaling Acta Biotheor. (IF 1.3) Pub Date : 2022-12-20 A. Minarsky, S. Krymsky, C. Soulé, N. Morozova
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Correction to: Stem Cells and the Microenvironment: Reciprocity with Asymmetry in Regenerative Medicine. Acta Biotheor. (IF 1.3) Pub Date : 2022-12-09 Guglielmo Militello,Marta Bertolaso
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Modelling the Effect of Vaccination Program and Inter-state Travel in the Spread of COVID-19 in Malaysia Acta Biotheor. (IF 1.3) Pub Date : 2022-11-17 Muhamad Hifzhudin Noor Aziz, Ahmad Dzulhilmi Ahmad Safaruddin, Nor Aishah Hamzah, Siti Suzlin Supadi, Zhou Yuhao, Muhamad Afiq Aziz
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Infectious Disease Spreading Fought by Multiple Vaccines Having a Prescribed Time Effect Acta Biotheor. (IF 1.3) Pub Date : 2022-11-15 Rinaldo M. Colombo, Mauro Garavello
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Major Transitions as Groupoid Symmetry-Breaking in Nonergodic Prebiotic, Biological and Social Information Systems Acta Biotheor. (IF 1.3) Pub Date : 2022-10-29 Rodrick Wallace
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On the Role of Speed in Technological and Biological Information Transfer for Computations Acta Biotheor. (IF 1.3) Pub Date : 2022-10-26 János Végh, Ádám József Berki
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Stochastic Modeling and Forecasting of Covid-19 Deaths: Analysis for the Fifty States in the United States Acta Biotheor. (IF 1.3) Pub Date : 2022-09-16 Olusegun Michael Otunuga, Oluwaseun Otunuga
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Inferential Pluralism in Causal Reasoning from Randomized Experiments Acta Biotheor. (IF 1.3) Pub Date : 2022-08-13 Tudor M. Baetu
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Stem Cells and the Microenvironment: Reciprocity with Asymmetry in Regenerative Medicine Acta Biotheor. (IF 1.3) Pub Date : 2022-08-13 Militello Guglielmo, Bertolaso Marta
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COVID-19 Adaptive Humoral Immunity Models: Weakly Neutralizing Versus Antibody-Disease Enhancement Scenarios Acta Biotheor. (IF 1.3) Pub Date : 2022-08-13 Antoine Danchin, Oriane Pagani-Azizi, Gabriel Turinici, Ghozlane Yahiaoui
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An Epidemic Model with Pro and Anti-vaccine Groups Acta Biotheor. (IF 1.3) Pub Date : 2022-07-08 G. S. Harari, L. H. A. Monteiro
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Modelling the Influence of Climatic Factors on the Population Dynamics of Radopholus Similis: Banana-Plantain Pest Acta Biotheor. (IF 1.3) Pub Date : 2022-07-08 S. Fotso, G. Kolaye, J. Ntahomvukiye, S. Bowong, V. Taffouo
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Integration of Heterogeneous Biological Data in Multiscale Mechanistic Model Calibration: Application to Lung Adenocarcinoma Acta Biotheor. (IF 1.3) Pub Date : 2022-07-07 Jean-Louis Palgen, Angélique Perrillat-Mercerot, Nicoletta Ceres, Emmanuel Peyronnet, Matthieu Coudron, Eliott Tixier, Ben M. W. Illigens, Jim Bosley, Adèle L’Hostis, Claudio Monteiro
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Bridging Theories for Ecosystem Stability Through Structural Sensitivity Analysis of Ecological Models in Equilibrium Acta Biotheor. (IF 1.3) Pub Date : 2022-06-23 Jan J. Kuiper, Bob W. Kooi, Garry D. Peterson, Wolf M. Mooij
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Limited Cognitive Abilities and Dominance Hierarchies Acta Biotheor. (IF 1.3) Pub Date : 2022-06-17 Hanyuan Huang, Jiabin Wu
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Optimal Drug Regimen and Combined Drug Therapy and Its Efficacy in the Treatment of COVID-19: A Within-Host Modeling Study Acta Biotheor. (IF 1.3) Pub Date : 2022-05-19 Bishal Chhetri, Vijay M. Bhagat, D. K. K. Vamsi, V. S. Ananth, Bhanu Prakash, Swapna Muthusamy, Pradeep Deshmukh, Carani B. Sanjeevi
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Reconstructing the Last Common Ancestor: Epistemological and Empirical Challenges Acta Biotheor. (IF 1.3) Pub Date : 2022-05-16 Amadeo Estrada, Edna Suárez-Díaz, Arturo Becerra
Reconstructing the genetic traits of the Last Common Ancestor (LCA) and the Tree of Life (TOL) are two examples of the reaches of contemporary molecular phylogenetics. Nevertheless, the whole enterprise has led to paradoxical results. The presence of Lateral Gene Transfer poses epistemic and empirical challenges to meet these goals; the discussion around this subject has been enriched by arguments
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Mathematical Analysis of Membrane Transporters Dynamics: A Calcium Fluxes Case Study Acta Biotheor. (IF 1.3) Pub Date : 2022-04-28 A. Perrillat-Mercerot, N. Deliot, A. Miranville, R. Guillevin, B. Constantin
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Finding or Creating a Living Organism? Past and Future Thought Experiments in Astrobiology Applied to Artificial Intelligence Acta Biotheor. (IF 1.3) Pub Date : 2022-04-28 Daniel S. Helman
This is a digest of how various researchers in biology and astrobiology have explored questions of what defines living organisms—definitions based on functions or structures observed in organisms, or on systems terms, or on mathematical conceptions like closure, chirality, quantum mechanics and thermodynamics, or on biosemiotics, or on Darwinian evolution—to clarify the field and make it easier for
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Nonlocal Reaction–Diffusion Equations in Biomedical Applications Acta Biotheor. (IF 1.3) Pub Date : 2022-03-17 M. Banerjee, M. Kuznetsov, O. Udovenko, V. Volpert
Nonlocal reaction–diffusion equations describe various biological and biomedical applications. Their mathematical properties are essentially different in comparison with the local equations, and this difference can lead to important biological implications. This review will present the state of the art in the investigation of nonlocal reaction–diffusion models in biomedical applications. We will consider
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Qualitative and Dynamical Analysis of a Bionomic Fishery Model with Prey Refuge Acta Biotheor. (IF 1.3) Pub Date : 2022-02-04 S. N. Raw, B. P. Sarangi
Predation and escaping from predation through hiding are two fundamental phenomena in ecology. The most common approach to reducing the chance of predation is to use a refuge. Here, we consider a three species fishery model system with prey refuge induced by a Holling type-II functional response. These three species of fish populations are named prey, middle predator, and top predator. Harvesting is
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The Hybrid Incidence Susceptible-Transmissible-Removed Model for Pandemics Acta Biotheor. (IF 1.3) Pub Date : 2022-01-29 Ryan Lester Benjamin
The susceptible-transmissible-removed (STR) model is a deterministic compartment model, based on the susceptible-infected-removed (SIR) prototype. The STR replaces 2 SIR assumptions. SIR assumes that the emigration rate (due to death or recovery) is directly proportional to the infected compartment’s size. The STR replaces this assumption with the biologically appropriate assumption that the emigration
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A Mathematical Model of the Transmission Dynamics of Bovine Schistosomiasis with Contaminated Environment Acta Biotheor. (IF 1.3) Pub Date : 2022-01-12 Solomon Kadaleka, Shirley Abelman, Jean M. Tchuenche
Schistosomiasis, a vector-borne chronically debilitating infectious disease, is a serious public health concern for humans and animals in the affected tropical and sub-tropical regions. We formulate and theoretically analyze a deterministic mathematical model with snail and bovine hosts. The basic reproduction number \(R_0\) is computed and used to investigate the local stability of the model’s steady
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Modeling the Waves of Covid-19 Acta Biotheor. (IF 1.3) Pub Date : 2021-12-27 Ivan Cherednik
The challenges with modeling the spread of Covid-19 are its power-type growth during the middle stages of the waves with the exponents depending on time, and that the saturation of the waves is mainly due to the protective measures and other restriction mechanisms working in the same direction. The two-phase solution we propose for modeling the total number of detected cases of Covid-19 describes the
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Average and Standard Deviation of the Error Function for Random Genetic Codes with Standard Stop Codons Acta Biotheor. (IF 1.3) Pub Date : 2021-12-17 Dino G. Salinas
The origin of the genetic code has been attributed in part to an accidental assignment of codons to amino acids. Although several lines of evidence indicate the subsequent expansion and improvement of the genetic code, the hypothesis of Francis Crick concerning a frozen accident occurring at the early stage of genetic code evolution is still widely accepted. Considering Crick’s hypothesis, mathematical
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A Partition Theorem for a Randomly Selected Large Population Acta Biotheor. (IF 1.3) Pub Date : 2021-12-16 Rao, Arni S. R. Srinivasa
A theorem on the partitioning of a randomly selected large population into stationary and non-stationary components by using a property of the stationary population identity is stated and proved. The methods of partitioning demonstrated are original and these are helpful in real-world situations where age-wise data is available. Applications of this theorem for practical purposes are summarized at
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Achieving Minimum-Time Biological Conservation and Pest Management for Additional Food provided Predator–Prey Systems involving Inhibitory Effect: A Qualitative Investigation Acta Biotheor. (IF 1.3) Pub Date : 2021-12-14 Ananth, V S, Vamsi, D. K. K.
Theoretical and experimental studies on prey–predator systems where predator is supplied with alternate sources of food have received significant attention over the years due to their relevance in achieving biological conservation and biological control. Some of the outcomes of these studies suggest that with appropriate quality and quantity of additional food, the system can be steered towards any
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Host Manipulation Mechanisms of SARS-CoV-2 Acta Biotheor. (IF 1.3) Pub Date : 2021-12-13 Massey, Steven E.
Viruses are the simplest of pathogens, but possess sophisticated molecular mechanisms to manipulate host behavior, frequently utilizing molecular mimicry. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to bind to the host receptor neuropilin-1 in order to gain entry into the cell. To do this, the virus utilizes its spike protein polybasic cleavage site (PCS), which mimics
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The Concept of Evenness/Unevenness: Less Evenness or More Unevenness? Acta Biotheor. (IF 1.3) Pub Date : 2021-12-10 Gregorius, Hans-Rolf, Gillet, Elizabeth M.
While evenness is understood to be maximal if all types (species, genotypes, alleles, etc.) are represented equally (via abundance, biomass, area, etc.), its opposite, maximal unevenness, either remains conceptually in the dark or is conceived as the type distribution that minimizes the applied evenness index. The latter approach, however, frequently leads to conceptual inconsistency due to the fact
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The $$a$$ a -Wave of the Electroretinogram and Iron-Induced Oxidative Stress: A Model Acta Biotheor. (IF 1.3) Pub Date : 2021-12-06 Pattanaik, Deepak K., Sahu, Amir Prasad, Lakshminarayanan, Vasudevan, Sharma, Nachieketa K.
In photoreceptors of a dark adapted eye, the inward flux of sodium and calcium ions in the outer segment is balanced by the outward flux of potassium ions. But in the presence of light the creation of cyclic guanosine monophosphate in the outer segment decreases. Due to low concentration of cG (cyclic GMP) the channels in the outer segment open relatively less and thus the influx of calcium ion decreases
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The Indeterminacy Bottleneck: Implications for Habitable Worlds Acta Biotheor. (IF 1.3) Pub Date : 2021-12-04 von Hegner, Ian
It is often assumed that the transition between chemical evolution and biological evolution undergoes a smooth process; that once life has arisen, it will automatically ‘flood’ a solar system body. However, there is no a priori reason to assume that a link between them is a given. The fact that both chemical evolution and biological evolution meet in a single point can be critical. Thus, one may ask:
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Toward a More General Understanding of Bohr’s Complementarity: Insights from Modeling of Ion Channels Acta Biotheor. (IF 1.3) Pub Date : 2021-09-28 Kesić, Srdjan
Some contemporary theorists such as Mazzocchi, Theise and Kafatos are convinced that the reformed complementarity may redefine how we might exploit the complexity theory in 21st-century life sciences research. However, the motives behind the profound re-invention of “biological complementarity” need to be substantiated with concrete shreds of evidence about this principle’s applicability in real-life
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Strong Emergence in Biological Systems: Is It Open to Mathematical Reasoning? Acta Biotheor. (IF 1.3) Pub Date : 2021-08-31 Hao, Zhifeng, Liu, Jiayou, Wu, Biao, Yu, Min, Wegner, Lars H.
Complex, multigenic biological traits are shaped by the emergent interaction of proteins being the main functional units at the molecular scale. Based on a phenomenological approach, algorithms for quantifying two different aspects of emergence were introduced (Wegner and Hao in Progr Biophys Mol Biol 161:54–61, 2021) describing: (i) pairwise reciprocal interactions of proteins mutually modifying their
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Optimal Control Strategies and Sensitivity Analysis of an HIV/AIDS-Resistant Model with Behavior Change Acta Biotheor. (IF 1.3) Pub Date : 2021-07-30 Rabiu, Musa, Willie, Robert, Parumasur, Nabendra
Despite several research on HIV/AIDS, it is still incumbent to investigate more effective control measures to mitigate its infection level. Therefore, we introduce an HIV/AIDS-resistant model with behavior change and study its basic properties. In order to determine the most sensitive parameters that are responsible for disease transmission with respect to the basic reproduction number and those responsible
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Organic Codes: A Unifying Concept for Life Acta Biotheor. (IF 1.3) Pub Date : 2021-07-30 de Farias, Savio Torres, Prosdocimi, Francisco, Caponi, Gustavo
Although the knowledge about biological systems has advanced exponentially in recent decades, it is surprising to realize that the very definition of Life keeps presenting theoretical challenges. Even if several lines of reasoning seek to identify the essence of life phenomenon, most of these thoughts contain fundamental problem in their basic conceptual structure. Most concepts fail to identify either
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Factors in Protobiomonomer Selection for the Origin of the Standard Genetic Code Acta Biotheor. (IF 1.3) Pub Date : 2021-07-20 Alexander I. Saralov
Natural selection of specific protobiomonomers during abiogenic development of the prototype genetic code is hindered by the diversity of structural, spatial, and rotational isomers that have identical elemental composition and molecular mass (M), but can vary significantly in their physicochemical characteristics, such as the melting temperature Tm, the Tm:M ratio, and the solubility in water, due