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Modeling of Mouse Experiments Suggests that Optimal Anti-Hormonal Treatment for Breast Cancer is Diet-Dependent Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-18 Tuğba Akman, Lisa M. Arendt, Jürgen Geisler, Vessela N. Kristensen, Arnoldo Frigessi, Alvaro Köhn-Luque
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$$R_0$$ May Not Tell Us Everything: Transient Disease Dynamics of Some SIR Models Over Patchy Environments Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-15 Ao Li, Xingfu Zou
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Nonlinear Regression Modelling: A Primer with Applications and Caveats Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-15
Abstract Use of nonlinear statistical methods and models are ubiquitous in scientific research. However, these methods may not be fully understood, and as demonstrated here, commonly-reported parameter p-values and confidence intervals may be inaccurate. The gentle introduction to nonlinear regression modelling and comprehensive illustrations given here provides applied researchers with the needed
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Discretised Flux Balance Analysis for Reaction–Diffusion Simulation of Single-Cell Metabolism Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-06 Yin Hoon Chew, Fabian Spill
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A Mathematical Model of Stroma-Supported Allometric Tumor Growth Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-06 Rachel Leander, Greg Owanga, David Nelson, Yeqian Liu
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Modelling the Effects of Growth and Remodelling on the Density and Structure of Cancellous Bone Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-04 Brianna L. Martin, Karen J. Reynolds, Nicola L. Fazzalari, Murk J. Bottema
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Parameter Identifiability in PDE Models of Fluorescence Recovery After Photobleaching Bull. Math. Biol. (IF 3.5) Pub Date : 2024-03-02 Maria-Veronica Ciocanel, Lee Ding, Lucas Mastromatteo, Sarah Reichheld, Sarah Cabral, Kimberly Mowry, Björn Sandstede
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First Passage Times of Long Transient Dynamics in Ecology Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-23 Grant R. Poulsen, Claire E. Plunkett, Jody R. Reimer
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3D Genome Reconstruction from Partially Phased Hi-C Data Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-22
Abstract The 3-dimensional (3D) structure of the genome is of significant importance for many cellular processes. In this paper, we study the problem of reconstructing the 3D structure of chromosomes from Hi-C data of diploid organisms, which poses additional challenges compared to the better-studied haploid setting. With the help of techniques from algebraic geometry, we prove that a small amount
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Order-of-Mutation Effects on Cancer Progression: Models for Myeloproliferative Neoplasm Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-16 Yue Wang, Blerta Shtylla, Tom Chou
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Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-14 Abhishek Mallela, Ye Chen, Yen Ting Lin, Ely F. Miller, Jacob Neumann, Zhili He, Kathryn E. Nelson, Richard G. Posner, William S. Hlavacek
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Optimal Control with RdCVFL for Degenerating Photoreceptors Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-12 Kathryn Wifvat, Erika T. Camacho, Matthias Kawski, Thierry Léveillard, Stephen Wirkus
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A Model for Membrane Degradation Using a Gelatin Invadopodia Assay Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-12 Giorgia Ciavolella, Nathalie Ferrand, Michéle Sabbah, Benoît Perthame, Roberto Natalini
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Distinguishing Between Long-Transient and Asymptotic States in a Biological Aggregation Model Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-11 Jonathan R. Potts, Kevin J. Painter
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Infectious Disease in the Workplace: Quantifying Uncertainty in Transmission Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-01 Jonathan I. D. Hamley, Guido Beldi, Daniel Sánchez-Taltavull
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A Generalized Kinetic Model of Fractional Order Transport Dynamics with Transit Time Heterogeneity in Microvascular Space Bull. Math. Biol. (IF 3.5) Pub Date : 2024-02-01 Stefan Hindel
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Ranked Subtree Prune and Regraft Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-31
Abstract Phylogenetic trees are a mathematical formalisation of evolutionary histories between organisms, species, genes, cancer cells, etc. For many applications, e.g. when analysing virus transmission trees or cancer evolution, (phylogenetic) time trees are of interest, where branch lengths represent times. Computational methods for reconstructing time trees from (typically molecular) sequence data
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Lyme Disease Models of Tick-Mouse Dynamics with Seasonal Variation in Births, Deaths, and Tick Feeding Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-31 Kateryna Husar, Dana C. Pittman, Johnny Rajala, Fahad Mostafa, Linda J. S. Allen
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Making Your Own Luck: Weak Vertical Swimming Improves Dispersal Success for Coastal Marine Larvae Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-28 Alexander D. Meyer, Alan Hastings, John L. Largier
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A Kinetic Finite Volume Discretization of the Multidimensional PIDE Model for Gene Regulatory Networks Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-22 Mihály A. Vághy, Irene Otero-Muras, Manuel Pájaro, Gábor Szederkényi
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Turing Instabilities are Not Enough to Ensure Pattern Formation Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-22 Andrew L. Krause, Eamonn A. Gaffney, Thomas Jun Jewell, Václav Klika, Benjamin J. Walker
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Understanding the Interplay of CAR-NK Cells and Triple-Negative Breast Cancer: Insights from Computational Modeling Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-19 Abazar Arabameri, Samaneh Arab
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A Countable-Type Branching Process Model for the Tug-of-War Cancer Cell Dynamics Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-18 Ren-Yi Wang, Marek Kimmel
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Predicting Radiotherapy Patient Outcomes with Real-Time Clinical Data Using Mathematical Modelling Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-18 Alexander P. Browning, Thomas D. Lewin, Ruth E. Baker, Philip K. Maini, Eduardo G. Moros, Jimmy Chaudell, Helen M. Byrne, Heiko Enderling
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Sexual Dimorphism in Substrate Metabolism During Exercise Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-16 Stéphanie M. C. Abo, Elisa Casella, Anita T. Layton
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Bat Motion can be Described by Leap Frogging Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-10 Lucy Henley, Owen Jones, Fiona Mathews, Thomas E. Woolley
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A Semi-Markov Approach to Study a Group of Kinesin Motors Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-06 Lifeng Han, John Fricks
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Turing Pattern Formation in Reaction-Cross-Diffusion Systems with a Bilayer Geometry Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-03 Antoine Diez, Andrew L. Krause, Philip K. Maini, Eamonn A. Gaffney, Sungrim Seirin-Lee
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Dynamics of Lotka–Volterra Competition Patch Models in Streams with Two Branches Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-05 Weiwei Liu, Jie Liu, Shanshan Chen
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Local Identifiability Analysis, Parameter Subset Selection and Verification for a Minimal Brain PBPK Model Bull. Math. Biol. (IF 3.5) Pub Date : 2024-01-03 Kamala Dadashova, Ralph C. Smith, Mansoor A. Haider
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Connecting Agent-Based Models with High-Dimensional Parameter Spaces to Multidimensional Data Using SMoRe ParS: A Surrogate Modeling Approach Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-30 Daniel R. Bergman, Kerri-Ann Norton, Harsh Vardhan Jain, Trachette Jackson
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Generation of Orchard and Tree-Child Networks Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-20 Gabriel Cardona, Gerard Ribas, Joan Carles Pons
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Dynamics of a Mosquito Egg-Larvae Model with Seasonality Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-18 Jesús Bellver-Arnau, Alessandro Margheri, Carlota Rebelo
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Formation and Growth of Co-Culture Tumour Spheroids: New Compartment-Based Mathematical Models and Experiments Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-13 Ryan J. Murphy, Gency Gunasingh, Nikolas K. Haass, Matthew J. Simpson
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Models for Implant-Induced Capsular Contracture Post Breast Cancer Surgery Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-13 Cheryl Dyck, Kathryn V. Isaac, Leah Edelstein-Keshet
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Towards Inferring Network Properties from Epidemic Data Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-08 Istvan Z. Kiss, Luc Berthouze, Wasiur R. KhudaBukhsh
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Information-Theoretic Analysis of a Model of CAR-4-1BB-Mediated NFκB Activation Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-01 Vardges Tserunyan, Stacey Finley
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Novel Aspects in Pattern Formation Arise from Coupling Turing Reaction–Diffusion and Chemotaxis Bull. Math. Biol. (IF 3.5) Pub Date : 2023-12-01 Camile Fraga Delfino Kunz, Alf Gerisch, James Glover, Denis Headon, Kevin John Painter, Franziska Matthäus
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Pattern Formation in Mesic Savannas Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-27 Denis Patterson, Simon Levin, Ann Carla Staver, Jonathan Touboul
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Empirical Quantification of Predictive Uncertainty Due to Model Discrepancy by Training with an Ensemble of Experimental Designs: An Application to Ion Channel Kinetics Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-24 Joseph G. Shuttleworth, Chon Lok Lei, Dominic G. Whittaker, Monique J. Windley, Adam P. Hill, Simon P. Preston, Gary R. Mirams
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Optimizing Antimicrobial Treatment Schedules: Some Fundamental Analytical Results Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-23 Guy Katriel
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Temporary Cross-Immunity as a Plausible Driver of Asynchronous Cycles of Dengue Serotypes Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-14 Tak Fung, Hannah E. Clapham, Ryan A. Chisholm
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Optimization Therapy by Coupling Intermittent Androgen Suppression with Impulsive Chemotherapy for a Prostate Cancer Model Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-07 Yongzhen Pei, Yunfei Lv, Changguo Li, Dandan Fang
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A Nonlinear Delay Model for Metabolic Oscillations in Yeast Cells Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-07 Max M. Chumley, Firas A. Khasawneh, Andreas Otto, Tomas Gedeon
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Forced Traveling Waves in a Reaction-Diffusion Equation with Strong Allee Effect and Shifting Habitat Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-03 Bingtuan Li, Garrett Otto
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A Multigenerational Turing Model Reproduces Transgressive Petal Spot Phenotypes in Hybrid Mimulus Bull. Math. Biol. (IF 3.5) Pub Date : 2023-11-01 Emily S. G. Simmons, Arielle M. Cooley, Joshua R. Puzey, Gregory D. ConradiSmith
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Temporal and Probabilistic Comparisons of Epidemic Interventions Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-19 Mariah C. Boudreau, Andrea J. Allen, Nicholas J. Roberts, Antoine Allard, Laurent Hébert-Dufresne
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Ribosome Abundance Control in Prokaryotes Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-20 Jacob Shea, Lisa Davis, Bright Quaye, Tomas Gedeon
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Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-19 R. Eftimie, G. Rolin, O. E. Adebayo, S. Urcun, F. Chouly, S. P. A. Bordas
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Placing Approach-Avoidance Conflict Within the Framework of Multi-objective Reinforcement Learning Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-14 Enkhzaya Enkhtaivan, Joel Nishimura, Amy Cochran
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Assessing Markovian and Delay Models for Single-Nucleus RNA Sequencing Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-12 Gennady Gorin, Shawn Yoshida, Lior Pachter
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Ex Vivo Experiments Shed Light on the Innate Immune Response from Influenza Virus Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-13 Daniel Olmos Liceaga, Sandro Filipe Nunes, Roberto A. Saenz
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VisualPDE: Rapid Interactive Simulations of Partial Differential Equations Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-12 Benjamin J. Walker, Adam K. Townsend, Alexander K. Chudasama, Andrew L. Krause
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Generalized Stressors on Hive and Forager Bee Colonies Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-12 David C. Elzinga, W. Christopher Strickland
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Free and Interfacial Boundaries in Individual-Based Models of Multicellular Biological systems Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-08 Domenic P. J. Germano, Adriana Zanca, Stuart T. Johnston, Jennifer A. Flegg, James M. Osborne
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Direct Estimation of Parameters in ODE Models Using WENDy: Weak-Form Estimation of Nonlinear Dynamics Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-05 David M. Bortz, Daniel A. Messenger, Vanja Dukic
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An Adaptive Generalized Leaky Integrate-and-Fire Model for Hippocampal CA1 Pyramidal Neurons and Interneurons Bull. Math. Biol. (IF 3.5) Pub Date : 2023-10-04 Addolorata Marasco, Emiliano Spera, Vittorio De Falco, Annalisa Iuorio, Carmen Alina Lupascu, Sergio Solinas, Michele Migliore
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Coupling Mountain Pine Beetle and Forest Population Dynamics Predicts Transient Outbreaks that are Likely to Increase in Number with Climate Change Bull. Math. Biol. (IF 3.5) Pub Date : 2023-09-29 Micah Brush, Mark A. Lewis
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Rearrangement Events on Circular Genomes Bull. Math. Biol. (IF 3.5) Pub Date : 2023-09-25 Joshua Stevenson, Venta Terauds, Jeremy Sumner
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The Dynamics of Pasture–Herbivores–Carnivores with Sigmoidal Density Dependent Harvesting Bull. Math. Biol. (IF 3.5) Pub Date : 2023-09-19 Harald Bergland, Evgenii Burlakov, John Wyller