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Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study Lancet Psychiatry (IF 77.056) Pub Date : 2022-08-03 Jeanne Wolstencroft, Francesca Wicks, Ramya Srinivasan, Sarah Wynn, Tamsin Ford, Kate Baker, Samuel J R A Chawner, Jeremy Hall, Marianne B M van den Bree, Michael J Owen
Background Children with intellectual disability frequently have multiple co-morbid neuropsychiatric conditions and poor physical health. Genomic testing is increasingly recommended as a first-line investigation for these children. We aim to determine the effect of genomics, inheritance, and socioeconomic deprivation on neuropsychiatric risk in children with intellectual disability of genetic origin
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Neuropsychiatric risk in children with intellectual disability: knowns and unknowns Lancet Psychiatry (IF 77.056) Pub Date : 2022-08-03 Marina Mihaljevic
Abstract not available
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Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits Lancet Psychiatry (IF 77.056) Pub Date : 2022-08-02 Todd Lencz, Maya Sabatello, Anna Docherty, Roseann E Peterson, Takahiro Soda, Jehannine Austin, Laura Bierut, David Crepaz-Keay, David Curtis, Franziska Degenhardt, Laura Huckins, Gabriel Lazaro-Munoz, Manuel Mattheisen, Bettina Meiser, Holly Peay, Marcella Rietschel, Consuelo Walss-Bass, Lea K Davis
Private companies have begun offering services to allow parents undergoing in-vitro fertilisation to screen embryos for genetic risk of complex diseases, including psychiatric disorders. This procedure, called polygenic embryo screening, raises several difficult scientific and ethical issues, as discussed in this Personal View. Polygenic embryo screening depends on the statistical properties of polygenic
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Correction to Lancet Psychiatry 2022; 9: 574–83 Lancet Psychiatry (IF 77.056) Pub Date : 2022-08-01
Abstract not available
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Social thinning and stress generation after childhood maltreatment: a neurocognitive social transactional model of psychiatric vulnerability Lancet Psychiatry (IF 77.056) Pub Date : 2022-08-01 Eamon McCrory, Lucy Foulkes, Essi Viding
Childhood maltreatment is associated with significant, enduring risk of psychiatric disorder. In this paper, we review how neurocognitive alterations after maltreatment might indirectly increase the risk of psychiatric disorder via their impact on social functioning. We propose a neurocognitive social transactional model, within which the neurocognitive sequelae of maltreatment are postulated to affect
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Prevalence of suicidal ideation and self-harm behaviours in children aged 12 years and younger: a systematic review and meta-analysis Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-27 Marie-Claude Geoffroy, Samantha Bouchard, Megan Per, Bassam Khoury, Elise Chartrand, Johanne Renaud, Gustavo Turecki, Ian Colman, Massimiliano Orri
Background Suicide in children is a pressing public health concern. The increasing number of deaths by suicide and emergency visits for suicidal ideation and self-harm in children might not be fully representative; it is likely that many more children are in distress but do not seek out help. We conducted a systematic review and meta-analysis of existing studies to quantify the prevalence of suicidal
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Association of cannabis potency with mental ill health and addiction: a systematic review Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-25 Kat Petrilli, Shelan Ofori, Lindsey Hines, Gemma Taylor, Sally Adams, Tom P Freeman
Cannabis potency, defined as the concentration of Δ9-tetrahydrocannabinol (THC), has increased internationally, which could increase the risk of adverse health outcomes for cannabis users. We present, to our knowledge, the first systematic review of the association of cannabis potency with mental health and addiction (PROSPERO, CRD42021226447). We searched Embase, PsycINFO, and MEDLINE (from database
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The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity: a UK primary care cohort study of disease burden over 10 years Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-21 Naomi Launders, Leiah Kirsh, David P J Osborn, Joseph F Hayes
Background Despite increased rates of physical health problems in people with schizophrenia, bipolar disorder, and other psychotic illnesses, the temporal relationship between physical disease acquisition and diagnosis of a severe mental illness remains unclear. We aimed to determine the cumulative prevalence of 24 chronic physical conditions in people with severe mental illness from 5 years before
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HIV, substance use, and mental health care in prisons Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Seena Fazel, Daniel J Bromberg, Frederick L Altice
Abstract not available
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Prevention is better than cure Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 The Lancet Psychiatry
Abstract not available
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Depression in Indians 45 years and older: a roadblock in healthy ageing Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Rahul Shidhaye
Abstract not available
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Reconsidering the definition of trauma Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Jaimie L Gradus, Sandro Galea
Abstract not available
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Policy changes needed to address the mental health impact of COVID-19 in Iran Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Leila Doshmangir, Kamal Gholipour, Vladimir Sergeevich Gordeev
Abstract not available
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Cultivating collaboration in mania Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Bart Lutters
Abstract not available
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Continuing the conversation around opioid use disorder and post-traumatic stress disorder comorbidity Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Jaymin Upadhyay, Christopher D Verrico, Mariesa Cay, Sanda Kodele, Luba Yammine, George F Koob, Rudy Schreiber
Abstract not available
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Paola Dazzan: exploring without fear Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Priya Venkatesan
Abstract not available
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Sub-national patterns and correlates of depression among adults aged 45 years and older: findings from wave 1 of the Longitudinal Ageing Study in India Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-14 Arokiasamy Perianayagam, Matthew Prina, Y Selvamani, Dipika Gudekar, Supriya Salvi, Mathew Varghese, Rakhi Dandona
Background Depression is a major public health challenge linked with several poor health outcomes and disabilities among adults aged 45 years and older in India. We aimed to describe the prevalence of depression and its association with a variety of sociodemographic correlates and co-existing health conditions for this age group in India and its states. Methods In this prospective cohort study, data
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Strategies for managing patients with psychiatric illness in the reopening period of the COVID-19 pandemic in China Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-13 Wei Bai, Yuan Feng, Teris Cheung, Zhaohui Su, Chee H Ng, Yu-Tao Xiang
Abstract not available
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More phenomenology in psychiatry? Applied ontology as a method towards integration Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-08 Rasmus R Larsen, Luca F Maschião, Valter L Piedade, Guilherme Messas, Janna Hastings
There have been renewed calls to use phenomenology in psychiatry to improve knowledge about causation, diagnostics, and treatment of mental health conditions. A phenomenological approach aims to elucidate the subjective experiences of mental health, which its advocates claim have been largely neglected by current diagnostic frameworks in psychiatry (eg, DSM-5). The consequence of neglecting rich phenomenological
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Correction to Lancet Psychiatry 2022; 9: e32 Lancet Psychiatry (IF 77.056) Pub Date : 2022-07-06
Abstract not available
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Intensive home treatment in different settings Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-30 Claire Henderson
Abstract not available
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The effectiveness of intensive home treatment as a substitute for hospital admission in acute psychiatric crisis resolution in the Netherlands: a two-centre Zelen double-consent randomised controlled trial Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-30 Jurgen Cornelis, Ansam Barakat, Matthijs Blankers, Jaap Peen, Nick Lommerse, Merijn Eikelenboom, Jeroen Zoeteman, Henricus Van, Aartjan T F Beekman, Jack Dekker
Background Although de-institutionalisation has been underway for decades, admission to hospital followed by low-intensity outpatient care remains the usual treatment for patients with an acute psychiatric crisis. Intensive home treatment has been developed for patients in a severe psychiatric crisis as an alternative to inpatient care. This study aimed to evaluate the potential of intensive home treatment
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Relaxation of the criteria for entry to the UK Clozapine Central Non-Rechallenge Database: a modelling study Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-27 Ebenezer Oloyede, Eromona Whiskey, Cecilia Casetta, Olubanke Dzahini, Danielle Dunnett, Shreyans Gandhi, Fiona Gaughran, Sukhi Shergill, Philip McGuire, James H MacCabe, David Taylor
Background Clozapine is uniquely effective in treatment-resistant psychosis. In the UK, patients must discontinue clozapine indefinitely if they are placed on the Central Non-Rechallenge Database (CNRD) after their haematological parameters fall below particular thresholds. Under exceptional circumstances, patients can be rechallenged on clozapine under an off-licence agreement. In the USA in 2015
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Antipsychotic maintenance treatment versus dose reduction: how the story continues Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-23 Iris E C Sommer, Mark Horowitz, Kelly Allott, Helene Speyer, Marieke J H Begemann
Abstract not available
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Continuing, reducing, switching, or stopping antipsychotics in individuals with schizophrenia-spectrum disorders who are clinically stable: a systematic review and network meta-analysis Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-23 Giovanni Ostuzzi, Giovanni Vita, Federico Bertolini, Federico Tedeschi, Beatrice De Luca, Chiara Gastaldon, Michela Nosé, Davide Papola, Marianna Purgato, Cinzia Del Giovane, Christoph U Correll, Corrado Barbui
Background Although antipsychotic maintenance treatment is widely recommended to prevent relapse in chronic psychoses, evidence-based guidelines do not provide clear indications on different maintenance treatment strategies, including continuing the antipsychotic at standard doses, reducing the dose, switching to another antipsychotic, or even stopping the antipsychotic. We aimed to compare the effectiveness
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Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-22 Ayana Jordan, Stephanie Quainoo, Charla Nich, Theresa A Babuscio, Melissa C Funaro, Kathleen M Carroll
Reports from uncontrolled trials and surveys suggest that there are disparities in substance-use outcomes for minoritised racial and ethnic populations, yet few of these disparities have emerged from randomised clinical trials (RCTs). We conducted a systematic review of RCTs published in English of Black or Latinx adults with any non-nicotine substance use disorder that reported rates of treatment
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Integrating HIV and substance misuse services: a person-centred approach grounded in human rights Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-21 Victoria Haldane, Anne-Sophie Jung, Chuan De Foo, Pami Shrestha, Elena Urdaneta, Eva Turk, Juan I Gaviria, Jesus Boadas, Kent Buse, J Jaime Miranda, Steffanie A Strathdee, Ashley Barratt, Michel Kazatchkine, Martin McKee, Helena Legido-Quigley
Integrating HIV-related care with treatment for substance use disorder provides an opportunity to better meet the needs of people living with these conditions. People with substance use disorder are rendered especially vulnerable by prevailing policies, structural inequalities, and stigmatisation. In this Series paper we analyse existing literature and empirical evidence from scoping reviews on integration
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Integrating mental health and substance use treatment with HIV care for people experiencing homelessness Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-21 Cheyenne M Garcia, Margot B Kushel
Abstract not available
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Shifting paradigms Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 The Lancet Psychiatry
Abstract not available
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Long-term mental health impacts of wounded UK combat personnel Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Lisa Dell
Abstract not available
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Why is the educational attainment of people with schizophrenia lagging so far behind? Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Eóin Killackey
Abstract not available
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Pathways to depressive and anxiety disorders during and after the COVID-19 pandemic Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 J C Lokman, C L Bockting
Abstract not available
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Real-world effectiveness studies of low doses of antipsychotics Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Fabrice Berna, Benoit Schorr, Hervé Javelot, Ludovic C Dormegny-Jeanjean, Jack R Foucher
Abstract not available
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Real-world effectiveness studies of low doses of antipsychotics – Authors' reply Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Heidi Taipale, Antti Tanskanen, Christoph U Correll, Jari Tiihonen
Abstract not available
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Clozapine and the risk of haematological malignancies Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Jose de Leon, Carlos De las Cuevas, Emilio J Sanz, Can-Jun Ruan, Christoph U Correll
Abstract not available
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Clozapine and the risk of haematological malignancies Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Peter FJ Schulte, Dan Cohen, Selene RT Veerman, Bert Bakker, Jan PAM Bogers
Abstract not available
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Clozapine and the risk of haematological malignancies – Authors' reply Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Jari Tiihonen, Antti Tanskanen, J Simon Bell, Jessica L Dawson, Vesa Kataja, Heidi Taipale
Abstract not available
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Unbalanced appraisal of psychosocial versus antipsychotic literature Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Mark Abie Horowitz, Klaus Munkholm, Joanna Moncrieff
Abstract not available
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Unbalanced appraisal of psychosocial versus antipsychotic literature – Authors’ reply Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Sameer Jauhar, Stephen M Lawrie
Abstract not available
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Peer support for discharge from inpatient mental health care Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Peter Phalen, Rebecca Miller, Barbara Frampton, Nev Jones, Karen Machin, Diana Rose, Hannah Stewart, Michelle Colder Carras
Abstract not available
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Peer support for discharge from inpatient mental health care – Authors' reply Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Steve Gillard, Sally Barlow, Stephen Bremner, Rhiannon Foster, Sarah Gibson, Lucy Goldsmith, Andrew Healey, Mike Lucock, Jacqueline Marks, Akshaykumar Patel, Shalini Patel, Stefan Priebe, Miles Rinaldi, Alan Simpson, Michael Ussher, Sarah White
Abstract not available
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Gambling harms and gambling disorder research funding Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Sian M Griffiths
Abstract not available
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Diagnostic labels: the problem is the signified not the signifier Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Fritz Handerer, Peter Kinderman, Sara Tai
Abstract not available
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DSM-5-TR turns normal grief into a mental disorder Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Joanne Cacciatore, Allen Francis
Abstract not available
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Digital psychological first aid in humanitarian contexts Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Richard Armitage
Abstract not available
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Laura Fischer: the art and science of transforming trauma Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Jules Morgan
Abstract not available
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Boston, USA Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 David Haosen Xiang
Abstract not available
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Mental health outcomes of male UK military personnel deployed to Afghanistan and the role of combat injury: analysis of baseline data from the ADVANCE cohort study Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Daniel Dyball, Alexander N Bennett, Susie Schofield, Paul Cullinan, Christopher J Boos, Anthony M J Bull, Simon Wessely, Sharon A M Stevelink, Nicola T Fear
Background The long-term psychosocial outcomes of UK armed forces personnel who sustained serious combat injuries during deployment to Afghanistan are largely unknown. We aimed to assess rates of probable post-traumatic stress disorder (PTSD), depression, anxiety, and mental health-associated multimorbidity in a representative sample of serving and ex-serving UK military personnel with combat injuries
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The enduring gap in educational attainment in schizophrenia according to the past 50 years of published research: a systematic review and meta-analysis Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-16 Nicolás A Crossley, Luz María Alliende, Leticia S Czepielewski, David Aceituno, Carmen Paz Castañeda, Camila Diaz, Barbara Iruretagoyena, Carlos Mena, Cristian Mena, Juan Pablo Ramirez-Mahaluf, Angeles Tepper, Javiera Vasquez, Lais Fonseca, Viviane Machado, Camilo E Hernández, Cristian Vargas-Upegui, Gladys Gomez-Cruz, Luis F Kobayashi-Romero, Ary Gadelha
Background Educational attainment is associated with wellbeing and health, but patients with schizophrenia achieve lower levels of education than people without. Several effective interventions can ameliorate this situation. However, the magnitude of the education gap in schizophrenia and its change over time are unclear. We aimed to reconstruct the trajectories of educational attainment in patients
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Intimate partner violence, suicidality, and self-harm: a probability sample survey of the general population in England Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-07 Sally McManus, Sylvia Walby, Estela Capelas Barbosa, Louis Appleby, Traolach Brugha, Paul E Bebbington, Elizabeth A Cook, Duleeka Knipe
Background Intimate partner violence (IPV) is a recognised risk factor for psychiatric disorders. There is little current evidence on IPV and self-harm and suicidality, and we therefore aimed to investigate the associations between experience of lifetime and past-year IPV with suicidal thoughts, suicide attempt, and self-harm in the past year. Methods We analysed the 2014 Adult Psychiatric Morbidity
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Intimate partner violence: breaking the silence Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-07 Eve Griffin, Ella Arensman
Abstract not available
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Comorbid opioid use disorder and post-traumatic stress disorder Lancet Psychiatry (IF 77.056) Pub Date : 2022-06-02 Igor Elman, David Borsook
Abstract not available
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The Ukrainian paediatric mental health system: challenges and opportunities from the Russo–Ukrainian war Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-22 Dmytro Martsenkovskyi, Igor Martsenkovsky, Inna Martsenkovska, Boris Lorberg
Abstract not available
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The importance of perinatal maternal depression as a public health problem in Africa Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-19 Symon M Kariuki, Charles R J C Newton
Abstract not available
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Trajectories and predictors of perinatal depressive symptoms among Kenyan women: a prospective cohort study Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-19 Anna Larsen, Jillian Pintye, Mary M Marwa, Salphine Watoyi, John Kinuthia, Felix Abuna, Barbra A Richardson, Laurén Gomez, Julia C Dettinger, Grace John-Stewart
Background There are gaps in understanding longitudinal patterns and predictors of perinatal depressive symptoms in sub-Saharan Africa. This study aimed to explore trajectories of depressive symptoms and associated factors from pregnancy to 9 months post partum among Kenyan women. Methods In this prospective cohort study, we analysed data from the PrEP Implementation for Mothers in Antenatal Care (PrIMA)
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A moment to savour Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-17 Jessica Catchpole
Abstract not available
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Intimate partner violence and trauma Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-12 The Lancet Psychiatry
Abstract not available
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Digital aids for relapse prevention in schizophrenia Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-12 Toshi A Furukawa, Irene Bighelli
Abstract not available
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Mental health care for survivors and others affected by intimate partner violence: the case for research and investment Lancet Psychiatry (IF 77.056) Pub Date : 2022-05-12 Rachel Jewkes
Abstract not available