This review utilizes the robust database of literature contained in toxicological profiles developed by the Agency for Toxic Substances and Disease Registry. The aim was to use this database to identify developmental toxicity studies reporting alterations in hormone levels in the developing fetus and offspring and identify windows of sensitivity. We identified 74 oral exposure studies in rats that

Spinosad and temefos are widely used pesticides for chemical control of dengue vector-borne disease (Aedes aegypti). The aim of this study was to compare the effect of acute exposure (7 days) to spinosad (0.5 mg A.I. L−1) and temefos (10 mg A.I. L−1), concentrations used by the Mexican Ministry of Health, on phagocytic capacity (PC) of mononuclear cells of guppies fish (Poecilia reticulata), as well

The presence of metal contaminants in agricultural soils and subsequent uptake by food crops can pose serious human health risk. In this study, we assessed the levels of toxic metals – arsenic, chromium, copper, iron, manganese, nickel, and zinc – in soils and some edible root tuber crops from two gold mining and two non-mining communities in Ghana to evaluate the potential human health risks associated

To explore the impact of air pollutants exposure during pregnancy on infant DNA methylation, we identified correlated methylated genes in maternal and cord blood samples using the Illumina Human Methylation 27 k BeadChip. Quantitative methylation-specific PCR (QMS-PCR) was performed to validate the target gene methylation pattern in 568 participants. Then the association between air pollutants exposure

For several years, environmental exogenous agents, called endocrine disruptors, are suspected to interfere with the essential functions of reproduction and development in many living organisms. In this study, endocrine disruptors including five phthalates and two bisphenols contents in finished products were assayed and their estrogenic activity were measured by using the Yeast Estrogen Screen system

The aim of this study was to compare the antibiotic susceptibility of eighty Escherichia coli isolates from vegetables and food products of animal origin in Tunisia, and to study their genes encoding antibiotic resistance and in vitro biofilm forming capacity. Antimicrobial susceptibilities were determined, as well as PCR investigation of genes associated with antibiotic resistance. Biofilm formation

Although literature shows that Cigarette Butt (CB) is not just litter but a toxic waste which has harmful effects on the environment, a large number of smokers litter their CBs onto the ground. This study explored the experiences of smokers in terms of CB littering behaviour. A qualitative content analysis study was conducted in Tehran, Iran in 2019. Twenty-seven semi-structured in-depth interviews

Obtaining food safety certification is essential for food manufacturers. Potential barriers to obtaining certification are complex, interrelated and broadly relate to, 'knowledge and skills', 'time, cost and resources', and 'communication and access to information'. This study aimed to explore requirements for support to enable food manufacturers in Wales to overcome identified barriers. Food manufacturers

Exposure of the general population to pesticides, especially in agricultural areas, is a major public health concern. This review analyses the role of Land Use and Land Cover (LULC) in Residential Exposure to Agricultural Pesticides (REAP) and how it is measured and modelled. Some epidemiological studies have shown that basic LULC variables, such as distance to a crop and field size, are relevant for

Environmental contaminants exposure may lead to detrimental changes to the microRNAs (miRNAs) expression resulting in several health effects. miRNAs, small non-coding RNAs that regulate gene expression, have multiple transcript targets and thereby regulate several signalling molecules. Even a minor alteration in the abundance of one miRNA can have deep effects on global gene expression. Altered patterns

The purpose of this paper is twofold: to explore the factors influencing the emergence and growth of informal e-waste activities and to examine workers' motivation for involvement in informal e-waste activities. Semi-structured interviews and observations among actors in the recently established Dagomba-Line e-waste site in Kumasi, Ghana were employed to gather relevant data. Emergence and growth of

Some heavy metals were detected in organs of the tomatoes grown in the discharge area of effluents of a municipal wastewater treatment plant. Also, the health risk potentials of heavy metals in the tomatoes consumed by human were investigated. The highest concentrations for Cu, Ni, Cr, Mn and Pb were followed the order of root>leaf>stem>fruit. When the bioconcentration factors values calculated for

The prevention and treatment of mental health disorders in childhood and adolescence is one among the major public health challenges in the United States today. Prior research has suggested that neighborhood is very important for children and adolescents' mental health. The present study extends the research on neighborhood and mental health by examining the association between childhood mental health

Our study aimed at assessing the determinants of hand hygiene and utilisation of bathing facilities in healthcare facilities (HCFs) in the greater Kampala metropolitan area, Uganda. Results indicate that 19.9% of the respondents wished to wash hands and failed while 39.3% faced challenges related to bathing. Failure to wash hands was associated with received information on hand washing (APR = 1.14

This study report the presence of polybrominated biphenyls (PBBs), polybrominated diphenyl ethers (PBDEs) and novel brominated flame-retardants (NBFRs) in muscle tissues of Labeo capensis (mudfish), Labeo umbratus (moggel), Cyprinus carpio (carp) and Clarias gariepinus (catfish) from Vaal River, South Africa. The concentrations (in ng g-1 wet weight (ww)) of these contaminants ranged from LOQ to 12

There have been three major global outbreaks of acute respiratory disease caused by coronavirus in the last two decades. The ongoing Coronavirus Disease 2019 (COVID-19) first emerged in Wuhan, China, is the most dangerous, which spread to 163 countries and 6 continents and caused a major public health emergency worldwide. The outbreak is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

BACKGROUND Both nature exposure and green exercise (GE) provide numerous health benefits. However, there are no studies examining the impact of childhood GE on adult health. METHODS 45 healthy adults (aged 69.8 ± 8.4 years) took part in the study, wearing a Firstbeat heart rate variability (HRV) monitor for 24 hours. Participants also completed questionnaires assessing childhood and adulthood nature

Earthworms are an ideal biological model in toxicity assays and environmental monitoring studies. In the present study, the reproductive toxicity and histopathological effects of Monocrotophos pesticide on an exotic epigeic Eudrilus eugeniae and an indigenous epigeic Perionyx barotensis earthworm were studied. Earthworm species were exposed to different concentrations of pesticide like 450 ppm, 500

In the laboratories staffs, there is potential for adverse health effects in exposure to chemicals. Therefore, risk assessment is one of the main issues to prevent these effects. The purpose of this study was to assess the health risk of laboratory staffs and compare the two methods, including 'Chemical Health Risk Assessment' (CHRA) and 'Regional Screening Levels' (RSLs), that developed by the Department

Despite experiencing hot weathers, limited studies from India explored relationships between ambient heat and health. We studied associations between heat and all-cause mortality to estimate heat threshold(s) affecting health, and examine other affecting dimensions. We conducted time-series analysis with daily maximum temperature and all-cause mortality data of Bhubaneswar city (March-July, 2007-2017)

To assess heavy metal pollution and human health risk, a total of 28 topsoil samples were collected during four seasons from seven agricultural soil sites near a famous smelter in Jiyuan, China. The maximum concentrations of Cd, Pb, Hg, As, Zn, Cu, Ni, and Cr were 26.00, 2601.00, 3.29, 65.00, 410.00, 156.30, 54.80, and 73.60 mg kg-1, respectively. Compared with the sampling site nearest to the smelter

Household air pollution from combustion of solid fuels is an important risk factor for morbidity and mortality, causing an estimated 2.6 million premature deaths globally in 2016. Self-reported health symptoms are a meaningful measure of quality of life, however, few studies have evaluated symptoms and quantitative measures of exposure to household air pollution. We assessed the cross-sectional association

The present work studied the pH, organic carbon, phosphorus (P), calcium (Ca), magnesium (Mg), and heavy metals Cu, Cr, Co and Pb in roadside agricultural soils of Jalandhar environs of Punjab, India. A total of 120 samples in triplicates were collected from different sites for assessment of heavy metal pollution. The mean values of Cu, Cr, Co and Pb were found below the permissible limits of Indian

This study aimed to explore the amenable factors contributing to the improvement in subjective well-being (SWB) immediately after a short-term visit to an urban park in an uncontrolled condition. Ninety-four park visitors from three urban parks completed a short questionnaire evaluating SWB (with two components: affect and life satisfaction) immediately before and after their park visit. In addition

The relationship between air pollution exposure and haematology remains controversial. Evidences in the effect of trace organic air pollutants and in the impact of such exposure on lipid and protein levels are scarce. This work investigated the health effects of medium-term exposure to traffic-related air pollution on both haematological and biochemical indices in animal models. Two groups of albino

Dust samples from roads classified based on traffic volumes (low, medium and high traffic) were collected from Muscat, Oman, and then analyzed for a dozen heavy metals. Their contents varied widely with mercury and iron, having the lowest and highest concentrations (0.59–0.80 and 406.10–429.00 ppm, respectively). Contrary to most metals detected, mercury and arsenic did not only exhibit increasing

To assess the association between fluoride exposure and children’s behavioural outcomes, we recruited 325 resident school-age children (7–13 years old) lived in Tongxu County of Henan Province in China. We measured urinary fluoride (UF) concentrations using the ion-selective electrode method. Children’s behavioural outcomes were assessed by Conners’ Parent Rating Scale-Revised, including conduct problems

Malaria remains a major public health problem, causing 435,000 deaths in 2017. The objective of this study was to estimate the prediction ability of vector species associated with the prediction power of environmental and socio-economic factors for malaria risk. Logistic regression was used for malaria risk estimation. A Radial Basis Function model was applied for estimating the predictive ability

Bacillary dysentery (BD) is an acute diarrheal disease prevalent in areas affected by socioeconomic disparities. We investigated BD risk and its associations with socioeconomic factors at the county-level in Jiangsu province, China using epidemiological and socioeconomic data from 2011–2014. We fitted four Bayesian hierarchical models with various prior specifications for random effects. As all model

Recent studies have reached mixed conclusions regarding the association between exposure to air pollutants and attention-deficit hyperactivity disorder (ADHD). We performed systematic review and meta-analysis to determine whether air pollutants were risk factors for the development of ADHD in children. We systematically searched databases for all relevant studies up to 2 July 2019. Together, the studies

Bioactive compounds, synthesized by photosynthetic microorganisms, have drawn the attention of the pharmaceutical field. This study aimed at evaluating synthesis and in vitro antioxidant capacity of phenolic compounds produced by a microalgae species P. boryanum, which was grown in six different culture media (standard BG11, modified BG11/MBG11, standard WC, modified WC, WC*2 and basal). The highest

The association between ambient temperature and cardiovascular mortality varied by regions, populations, and climates. We estimated the relative risk (RR) of cardiovascular mortality using 229,288 death cases of cardiovascular disease in Qingdao China from 1 January 2009, to 31 December 2017. A distributed lag non-linear model was used. The temperature showed a negative association with the cardiovascular

Formation of biofilms allows bacterial cells to survive in adverse environments. Nontuberculous mycobacteria are ubiquitous in aqueous environments, where they adhere to surfaces and create a biofilm. This has led to the emergence of healthcare-associated infections and the use of biomaterials in medicine. Essential oils (EO) are substances of natural origin whose effect on microorganisms has been

The toxicity of cadmium (Cd) occurs through accumulation in the environment. The precise mechanism underlying Cd toxicity remains unclear. Therefore, in the present study, we studied the effects of Cd on MM55.K cells and investigated the mechanisms underlying Cd-induced cell death. CdCl2 significantly elevated apoptotic cell death, mitochondrial membrane potential (ΔΨm) loss, and caspase-dependent

In this study, an integration of multi-criteria evaluation, geographic information system, and remote sensing techniques were used for site selection of medical waste landfills in Kermanshah, Iran. Also, an environmental risk assessment for the selected site has been conducted in order to minimize the possible hazardous. The GIS and remote sensing were used for acquiring and preparing layers and maps

Due to the massive increase in non-ionizing radiation emitting devices, the social concern about the possible malignancy to its exposure has increased the research interest. The International Commission on Non-Ionizing Radiation Protection (ICNIRP) included the radiofrequency electromagnetic field (RF-EMF) of mobile phones on the category 2B as ‘possibly’ carcinogenic to humans. Epidemiological studies

The current study aims at forming new prediction models to be employed in the approximating the possible uptake of a range of 10 heavy metals (HMs) (Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb and Zn) by Hordeum vulgare tissues including roots, shoots and grains following its growth in soil amended with sewage sludge (SS) using conditions employed in greenhouses. The present study determined an insignificant

Transmission of Pseudomonas aeruginosa along the food chain could cause gastrointestinal infections. To show this involvement, the prevalence, putative virulence genotype, and antibiotic resistance phenotype of P. aeruginosa isolates from stool of 1482 patients with community and hospital acquired diarrhea were compared with 87 isolates from the environmental samples. The results showed infection with

This study aimed to investigate the trends in childhood asthma hospitalization in regions with differing levels of air pollution in Taiwan, 2001-2012. Joinpoint regression was used to identify significant trend changes. The hospitalization rate varied according to gender, geographic region, and age. The incidence of childhood asthma hospitalization decreased from 127.99 to 76.67 (/100,000 population)

Virulent pathotypes of E. coli seriously affect the livestock regarding the misuse of antibiotics. All 180 samples collected from cow's environment and dairy shops in Qena, Egypt were serologically and molecularly positive for coliforms. Enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC), Enteroinvasive E. coli (EIEC) and Enterotoxigenic E. coli (ETEC) pathotypes were isolated from

Rice is the staple food of Bangladeshi people and is consumed at least twice a day. Thus, the presence of toxic metals in rice grains has become a major public health concern in Bangladesh. The present research was conducted to investigate the concentrations of toxic metals in rice grains and their possible human health risks in the Tangail district of Bangladesh. Toxic metals were measured by using

Understanding the spatio-temporal characteristics of air pollutants is essential to improving air quality. One aspect is the question of whether green spaces can reduce air pollutant concentrations. However, previous studies on this issue have reported mixed results. This study analyzed the spatio-temporal characteristics of NO2, PM2.5 and O3 in Fujian Province, Southeast China in 2015. In order to

Limited research has investigated self-catering university students' food hygiene practices that may increase their vulnerability to food poisoning. This study assessed the practice-related risk factors for food poisoning among 600 self-catering university students. A validated questionnaire was self-administered to collect data about their food hygiene practices in the previous 12 months. Factors

The present study examined how dimensions of perceived risk contributed to mosquito avoidance behaviors in a flood-prone area. Mosquito avoidance behaviors were classified into proactive (i.e. used repellant sources) and withdrawal/reactive (i.e. reduced outside activities) behaviors. After controlling for level of mosquito bites, increased scores for above normal perceived risk were associated with

The aim of this study was to characterize 59 Pseudomonas strains isolated from soil samples in terms of Inducible Beta-Lactamase (IBL), fluorescence production, antibiotic resistance, presence of plasmids and genetic diversity, as well as denitrification functional genes. Fourteen out of fifty-nine (23.7%) Pseudomonas isolates were identified as multidrug-resistant. To evaluate the contribution of

This study examined spatial patterns of obesogenic environments for US counties. We mapped the geographic dispersion of food and physical activity (PA) environments, assessed spatial clustering, and identified food and PA environment differences across U.S. regions and rurality categories. Substantial low food score clusters were located in the South and high score clusters in the Midwest and West

Urban vegetation can deposit dust to reduce pollution, and dust retention capacity of vegetation has become an important indicator for urban ecological construction. We selected five representative vegetation in Shanghai to explore the regularity of dust deposition on vegetation leaves. Due to the influence of leaf area and surface characteristics, the amount of dust deposition was significantly different

The Lime Basra (Citrus aurantifolia Linn., Rutaceae) plant also known as dried lime, and Limoo Omani, is used both as a spice in meals and as an herbal tea in the treatment of some diseases in the Middle East. It was aimed to determine the biological activity screening of the 70% methanol, ethanol extracts and infusion which were prepared from dried fruits. 1,1-diphenyl-2-picrylhydrazyl (DPPH●) and

Agricultural soils were collected from Mocorito river basin, to determine potentially toxic elements (PTEs) subtotal concentrations and geochemical fractionation, and evaluate their environmental and health risks. All sites showed low As and Cr concentrations. Subtotal concentrations (mg/kg) ranged between 6.8 and 25.6 for As, 1.9 and 2.5 for Cd and 22.5 and 55.1 for Cr. These values were classified

Phlebotomus neglectus is one of the most important vectors of visceral leishmaniasis in Southeast Europe and Asia Minor. It was aimed to study the impact of climate change on the seasonality and the range of the species for 2014–2060. In the inland areas of Asia Minor, the Balkan Peninsula and the Carpathian Basin the elongation of the activity season will reach or exceed the two months in the middle

A physiologically based pharmacokinetic (PBPK) model was developed to described uptake, disposition and clearance of bromate in the rat using published experimental data in rat. The rodent bromate model was extrapolated to human using species-specific physiological parameters and standard interspecies scaling of rate constants. The bromate model is kinetically linear (i.e. AUC and Cmax) across the

Individual attributes have been investigated to explain sedentary behavior. However, few studies have evaluated this association at the neighborhood level. This study aimed to determine the association between screen time (ST) among adolescents and perceived neighborhood characteristics. This cross-sectional study was conducted using a multistage household survey in Vespasiano, Brazil, in 2015–2016

Dengue is a major public health concern mainly in tropical and subtropical environments worldwide. Despite several attempts to prevent this disease occurring in tropical regions of Mexico, it has not yet been controlled. This work focused on spatial modeling of confirmed dengue fever cases that occurred during the period 2010–2014 in the Huasteca Potosina region of Mexico. Multivariable Logistic Regression

ABSTRACT We examined whether exercising indoors vs. outdoors reduced the cardio-respiratory effects of outdoor air pollution. Adults ≥55 were randomly assigned to exercise indoors when the Air Quality Health Index was ≥5 and outdoors on other days (intervention group, n = 37), or outdoors everyday (control group, n = 35). Both groups completed cardio-respiratory measurements before and after exercise

β-HgS, differing from environmental mercury pollutants (MeHgCl and HgCl2) in chemical form, is used as traditional medicine in Asian countries for thousands of years. In this study, Neuro-2a cells were exposed to β-HgS, MeHgCl and HgCl2 (5 µM) for 6-24 h. The cell viability of β-HgS was higher than MeHgCl with 25.9% and 72.4% in 12 h and 24 h respectively. As the incubation time increased, MeHgCl had

Van Lake is the third largest closed lake in the world and the biggest lake in Turkey. An ELISA method has developed with the aim of determining the pollution caused by estrogens and estrogen-like chemicals that have come to the lake Van in recent years. First, the vitellogenin in estrogen-treated male fish plasma was purified by ion exchange chromatography, injected into rats, and the obtained polyclonal

The study aimed to analyze the level of heavy metal pollution in the agricultural lands in the southern margin of Tarim Basin, Xinjiang, and its risks to human health. A total of 1765 soil samples were collected from the Cele-Ruoqiang area. The contents of soil As, Cd, Cr, Cu, Hg, Ni, Pb and Zn were analyzed using the pollution load index method. The results showed that soil was slightly contaminated

Pseudomonas aeruginosa is a major public health concern all around the world. In the frame of this work, a set of diverse environmental P. aeruginosa isolates with various antibiotic resistance profiles were examined in a Galleria mellonella virulence model. Motility, serotypes, virulence factors and biofilm-forming ability were also examined. Molecular types were determined by pulsed-field gel electrophoresis

Occupational pesticides exposure rises health concern due to genotoxicity and accumulation of pesticides in human biological matrices. Continuous and sublethal exposure to pesticides had been associated with oxidative stress, mutagenic and cell death. Exposure to pesticides exhibits increased level of DNA damage even if no detectable amounts of pesticides are seen in biological matrices by binding

Exposure to benzo[a]pyrene (B[a]P) may be a risk factor for pulmonary diseases. To investigate the correlations among B[a]P exposure level, DNA strand breaks and pulmonary inflammation, we recruited 83 children diagnosed with pulmonary diseases and 63 healthy children from Guangzhou, China. Results showed that the levels of Benzo[a]pyrene diol epoxide (BPDE) DNA adduct in blood and IL-8 in serum in