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Use of indexes of aortic flow derived from transthoracic echocardiography to evaluate the response to a fluid challenge in anesthetized dogs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2021-01-12 Guillermo CV. de Oliveira; Francisco J. Teixeira-Neto; Tábata L. Dalmagro; Angélica Alfonso; Nathalia Celeita-Rodríguez; César PC. Lobo; Maria LG. Lourenço
Objective To evaluate the ability of transthoracic echocardiographic aortic flow measurements to discriminate response to a fluid challenge (FC) in healthy anesthetized dogs. Study design Prospective experimental study. Animals A total of 48 isoflurane-anesthetized dogs (14.2–35.0 kg) undergoing elective surgery. Methods Fluid responsiveness was evaluated before surgery by a FC (lactated Ringer´s 10
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Questionnaire on the process of recovering horses from general anesthesia and associated personnel injury in equine practice Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2021-01-12 Cristina de Miguel Garcia; Luis Campoy; Stephen Parry; Julia Miller; Manuel Martin-Flores; Robin Gleed
Objective To collect data about the current practice of recovering horses from general anesthesia and recovery personnel safety. Study design Online survey. Methods An online questionnaire, including questions on general demographic data, recovery drugs, modality and characteristics of equine recovery and morbidity and mortality, was designed and distributed via email to equine practitioners worldwide
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Cyclooxygenases 1 and 2 inhibition and analgesic efficacy of dipyrone at different doses or meloxicam in cats after ovariohysterectomy Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-03 Marco AA. Pereira; Karina D. Campos; Lucas A. Gonçalves; Rosana ST. dos Santos; Patrícia B. Flôr; Aline M. Ambrósio; Denise A. Otsuki; Júlia M. Matera; Cristina OMS. Gomes; Denise T. Fantoni
Objective To evaluate the cyclooxygenases (COX) inhibition, adverse effects and analgesic efficacy of dipyrone or meloxicam in cats undergoing elective ovariohysterectomy. Study design Prospective, blinded, randomized, clinical study. Animals A total of 30 healthy young cats. Methods The cats were randomly assigned to three postoperative groups: D25 (dipyrone 25 mg kg−1 every 24 hours), D12.5 (dipyrone
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Evaluation of intramuscular sodium nitroprusside injection to improve oxygenation in white-tailed deer (Odocoileus virginianus) anesthetized with medetomidine–alfaxalone–azaperone Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-06 Sarifa Lakhdhir; Nigel Caulkett; Tanya Duke-Novakovski; Murray Woodbury; Søren Boysen
Objective In ungulates, α2-adrenergic agonists can decrease oxygenation possibly through alteration of pulmonary perfusion. Sodium nitroprusside can decrease pulmonary vascular resistance (PVR) and increase cardiac output (Q˙t) through vasodilation. The objective was to determine if sodium nitroprusside would improve pulmonary perfusion and attenuate the increased alveolar–arterial (a–a) gradient resulting
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The effect of erector spinae plane block on perioperative analgesic consumption and complications in dogs undergoing hemilaminectomy surgery: a retrospective cohort study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-02 Diego A. Portela; Marta Romano; Gustavo A. Zamora; Fernando Garcia-Pereira; Luisito S. Pablo; Bonnie J. Gatson; Alana N. Johnson; Pablo E. Otero
Objective To compare the perioperative use of analgesics and complication rates in dogs administered an erector spinae plane (ESP) block or a traditional opioid-based (OP) treatment as part of analgesic management during hemilaminectomy. Study design Retrospective cohort study. Animals Medical records of 114 client-owned dogs. Methods General data included demographics, duration of procedure, number
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Lumbar erector spinae plane block: an anatomical and dye distribution evaluation of two ultrasound-guided approaches in canine cadavers Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-11 Roger Medina-Serra; Andrew Foster; Mark Plested; Sandra Sanchis; Francisco Gil-Cano; Jaime Viscasillas
Objective To examine the anatomy of the lumbar epaxial region and to describe two different ultrasound-guided approaches for the lumbar erector spinae plane (ESP) block in dogs. Study design An anatomical and experimental cadaver study. Animals A group of 19 canine cadavers. Methods The anatomy was described following dissection of two cadavers. Bilateral ultrasound-guided ESP injections with 0.4 mL
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Along or across the visual axis: a comparison of two ultrasound screen, needle and transducer orientation techniques Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-04 Chiara Di Franco; Hamaseh Tayari; Samanta Nardi; Angela Briganti
Objective To evaluate two transducer and needle handling methods, along the visual axis (AL) and across the visual axis (AC), in non-skilled and skilled clinicians. Study design Prospective randomized crossover study. Method A total of 26 students with no ultrasound locoregional anaesthesia experience (non-skilled group) and six clinicians experienced and familiar with ultrasound locoregional anaesthesia
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Inhibition and facilitation of nociceptively evoked muscular activity by fentanyl or dexmedetomidine in isoflurane anaesthetized pigs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2021-01-01 Henning Andreas Haga; Andreas Lervik; Janicke Nordgreen
Objective To investigate motor and cardiovascular responses to dexmedetomidine or fentanyl in isoflurane anaesthetized pigs. Study design Experimental, balanced, block randomised, two group design. Animals A group of 16 crossbred pigs 55 ± 8 days (mean ± standard deviation) old. Methods Deltoid electromyography (EMG) was recorded during isoflurane anaesthesia. Electrical stimulation using 5, 10, 20
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Evaluation of the effect of ultrasound guidance on the accuracy of intercostal nerve injection: a canine cadaveric study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-30 Alexander C.S. Thomson; Diego A. Portela; Marta Romano; Pablo E. Otero
Objective To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers. Study design Prospective, randomized, descriptive, experimental anatomic study. Animals A total of 14 mid-sized adult canine cadavers. Methods Ultrasound landmarks were identified by dissection
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A comparison of four peribulbar anaesthetic techniques: a preliminary study in equine cadavers Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-29 V. Rabbogliatti; D. De Zani; D.D. Zani; F. Di Cesare; F.A. Brioschi; D. Gioeni; B. Crivellari; G. Ravasio
Objective To compare the peribulbar injectate distribution and probability of regional anaesthesia of four peribulbar anaesthetic techniques in equine cadavers. Study Design Prospective experimental cadaver study. Animals A total of 12 isolated equine cadaver heads and 24 eyes. Methods The 24 orbits underwent one of four injection techniques (six orbits each) with a mixture (1:4) of contrast medium
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Pharmacokinetics, efficacy, and convulsive dose of articaine hydrochloride in goat kids Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-29 Dinakaran Venkatachalam; John Paul Chambers; Kavitha Kongara; Neil Ward; Antony Jacob; Preet Mohinder Singh
Objective To investigate the pharmacokinetics, efficacy and convulsive dose of articaine hydrochloride in goat kids Study design Experimental prospective study Animals Total 18 (n = 6 animals per experiment) male Saanen goat kids (2-4 weeks old) Methods The study consisted of three experiments. The first determined the pharmacokinetics of articaine following intravenous administration of articaine
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Impact of surgical preparatory rinses with isopropyl alcohol or water on perioperative body temperature in pediatric female dogs and cats Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-29 Daniela Isaza; Brian A. DiGangi; Natalie Isaza; Ramiro Isaza
Objective To describe the effects of presurgical preparation with an isopropyl alcohol or water rinse on the perioperative rectal temperature (RT) of puppies and kittens. Study design Randomized clinical trial. Animals A total of 48 intact female mixed breed puppies and 43 intact female Domestic Short Hair kittens aged 8–18 weeks. Methods All animals were premedicated with intramuscular buprenorphine
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Evaluation of alfaxalone and midazolam with or without flumazenil reversal in Egyptian fruit bats (Rousettus aegyptiacus) Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-23 Avishag Tuval; Inbal Dror-Maman; Liora Las; Tali Bdolah-Abram; Yael Shilo-Benjamini
Objectives To evaluate alfaxalone–midazolam anesthesia in Egyptian fruit bats (Rousettus aegyptiacus) and the effect of flumazenil administration on recovery time and quality. Study design Randomized, blinded, crossover and controlled, experimental trial. Animals A total of 10 male Egyptian fruit bats. Methods Bats were anesthetized with alfaxalone (15 mg kg−1) and midazolam (2 mg kg−1) administered
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Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-23 Tainor Tisotti; Alexander Valverde; Ashley Hopkins; M Lynne O’Sullivan; Brad Hanna; Luis Arroyo
Objective To assess cardiopulmonary function in sedated and anesthetized dogs administered intravenous (IV) dexmedetomidine and subsequently administered IV lidocaine to treat the dexmedetomidine-induced bradycardia. Study design Prospective, randomized, crossover experimental trial. Animals A total of six purpose-bred female Beagle dogs, weighing 9.1 ± 0.6 kg (mean ± standard deviation). Methods Dogs
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Dose requirement and cardiopulmonary effects of diluted and undiluted propofol for induction of anaesthesia in dogs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-15 Hanna Rögels; Fernando Martinez-Taboada
Objective To compare the dose, cardiopulmonary effects and quality of anaesthetic induction in healthy dogs using propofol (10 mg mL-1) and diluted propofol (5 mg mL-1). Study design Randomized, blinded, clinical study. Animals A total of 28 client-owned dogs (12 males and 16 females). Methods Following intramuscular sedation using acepromazine 0.02 mg kg-1 and methadone 0.2 mg kg-1), propofol (10
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Quantification of reservoir bags as airway pressure limiting devices in a nonrebreathing system Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-11 Tamas D. Ambrisko; Arnon Gal; Jesus N. Sarol; Ashley Mitek; Christina Braun
Objective To evaluate the influence of reservoir bag types, volumes and previous use on the peak pressures (Pmax) and the times to develop 30 cmH2O pressure (P30) within a nonrebreathing system with a closed adjustable pressure limiting (APL) valve. Study design In vitro study using three-way factorial design with repeated measure on one-factor. Subjects A total of 75 new anesthesia reservoir bags
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Hemodynamic effects of incremental doses of acepromazine in isoflurane-anesthetized dogs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-09 Julia P.P. Rangel; Eduardo R. Monteiro; Flavia S. Bitti; Juarez S.N. Junior; Daniela Campagnol
Objective To evaluate the effects of incremental doses of acepromazine on hemodynamics in isoflurane-anesthetized dogs. Study design Prospective, experimental study. Animals Healthy, adult, mixed-breed dogs (two male and four female) weighing 16.8 ± 5.1 kg (mean ± standard deviation). Methods Dogs were anesthetized with propofol (7 mg kg−1) intravenously (IV) and isoflurane. Thermodilution and arterial
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Pharmacokinetics and pharmacodynamics of L-methadone in isoflurane-anaesthetized and mechanically ventilated ponies Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-09 Claudia Gittel; Ellen Schulz-Kornas; Friederike A. Sandbaumhüter; Regula Theurillat; Ingrid Vervuert; M. Paula Larenza Menzies; Wolfgang Thormann; Christina Braun
Objective To evaluate the pharmacokinetics and selected pharmacodynamic effects of a commercially available L-methadone/fenpipramide combination administered to isoflurane anaesthetized ponies. Study design Prospective single-group interventional study. Animals A group of six healthy adult research ponies (4 mares, 2 geldings). Methods Ponies were sedated with intravenous (IV) detomidine (0.02 mg kg-1)
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Agreement between noninvasive oscillometric and invasive blood pressure measurements in isoflurane-anesthetized guinea pigs (Cavia porcellus) Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-12-04 Samanta Waxman; Santiago Fuensalida; Fernanda Sánchez; Indiana Zárate; Emmanuel Turnes; Casilda Rodríguez; Pablo Otero
Objective To assess the agreement between an oscillometric device and invasive blood pressure measurements in anesthetized healthy adult guinea pigs. Study design Prospective experimental study. Animals A total of eight adult Hartley guinea pigs. Methods All animals were anesthetized; a carotid artery was surgically exposed and catheterized for invasive blood pressure (IBP) measurements. A size 1 cuff
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In-plane ultrasound-guided peribulbar block in the dog: an anatomical cadaver study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-11-19 Andrew Foster; Roger Medina-Serra; Sandra Sanchis-Mora; Mark Plested; Thaleia-Rengina Stathopoulou; Jaime Viscasillas
Objective To describe a new in-plane ultrasound-guided temporal approach to peribulbar block in the dog. Study Design Prospective experimental cadaver study. Animals A group of 10 beagle cadavers. Methods After describing the ultrasonographic (U/S) anatomy, peribulbar injection was performed bilaterally in 10 thawed Beagle cadavers by two randomly assigned operators. A 5-8 MHz microconvex U/S probe
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Comparison of blind intubation and a smartphone-based endoscope-assisted intubation in rabbits Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-05 André Saldanha; Eloisa Muehlbauer; Elaine MU. Gil; Tilde R. Froes; Juan CM. Duque; Rogerio R. Lange
Objective To compare between blind and smartphone-based endoscope-assisted techniques for endotracheal intubation in rabbits. Study design Prospective clinical study. Animals A total of 34 rabbits. Methods Rabbits were assigned to four groups: intubation by a veterinary anesthesiologist (VA) or an exotic pet medicine specialist (EPS) using blind or endoscope-assisted techniques. Propofol dose, number
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Mandibular nerve block in juvenile Nile crocodile: a cadaveric study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-06 Cristina Bianchi; Chiara Adami; Helen Dirrig; Andrew Cuff; Dario d’Ovidio; Paolo Monticelli
Objective To develop a technique for performing the mandibular nerve block in Nile crocodiles. Study design Experimental cadaveric study. Animals A total of 16 juvenile Nile crocodile heads. Methods To study the course of the mandibular nerve, one head was dissected. Computed tomography (CT) examination was performed in two heads to identify useful landmarks. Thereafter, a hypodermic needle was inserted
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Plasma histamine concentrations in horses administered sodium penicillin, guaifenesin–xylazine–ketamine and isoflurane with morphine or butorphanol Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-24 Tanya Duke-Novakovski; Carolina Palacios Jimenez; Masako Fujiyama; Shannon G. Beazley
Objective Various drugs administered to horses undergoing surgical procedures can release histamine. Histamine concentrations were evaluated in horses prepared for surgery and administered butorphanol or morphine intraoperative infusions. Study design Prospective studies with one randomized. Animals A total of 44 client-owned horses. Methods In one study, anesthesia was induced with xylazine followed
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An ultrasound-guided subparaneural approach to the sciatic nerve in the dog: a cadaver study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-21 Fabiana Micieli; Ludovica Chiavaccini; Giuseppina Mennonna; Giovanni Della Valle; Francesco Prisco; Leonardo Meomartino; Giancarlo Vesce
Objective To describe the gross and microscopic anatomy of the sciatic nerve paraneural sheath and to report an ultrasound (US)-guided subparaneural approach to the sciatic nerve in dogs, comparing two different volumes of injectate. Study design Prospective, randomized, anatomical study. Animals A group of nine middle-sized adult Mongrel canine cadavers (18 limbs). Methods The sciatic nerves of three
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Targeted fibre-optical intrabronchial lipopolysaccharide administration in pigs – a methodical refinement for improved accuracy in respiratory research Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-21 Robert Ruemmler; Alexander Ziebart; Elisabeth Britten; Jens Kamuf; Andreas Garcia-Bardon; Erik Kristoffer Hartmann
Objective To establish and evaluate a standardized method of targeted, intrabronchial drug delivery in pigs. Study design Randomized controlled trial. Animals A total of 16 German Landrace pigs (Sus scrofa), age range 12‒16 weeks, and weighing 28‒35 kg. Methods The animals were anaesthetized, intubated, and instrumented with extended cardiovascular monitoring. Lung injury was induced by administering
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Pharmacokinetics of carprofen in anaesthetized pigs: a preliminary study Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-19 Maša Bošnjak; Mojca Kržan; Urša Lampreht Tratar; Jožica Dolenc; Maja Čemažar; Alenka Seliškar
Objective To investigate the pharmacokinetics of carprofen after a single intravenous (IV) dose and multiple oral doses administered to pigs undergoing electroporation of the pancreas. Study design Prospective experimental study. Animals A group of eight female pigs weighing 31.74 ± 2.24 kg (mean ± standard deviation). Methods Carprofen 4 mg kg−1 was administered IV after placement of a central venous
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The effect of cannabidiol on sevoflurane minimum alveolar concentration reduction produced by morphine in rats Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-15 Cristina Orden; Martín Santos; María Ceprian; Francisco J. Tendillo
Objective To investigate the effect of cannabidiol (CBD) on sevoflurane minimum alveolar concentration (MACSEV) reduction produced by morphine in rats. Study design Randomized, blinded trial. Animals A total of 75 male Wistar Han rats weighing 276 ± 23 g (mean and standard deviation), aged 3 months. Methods Cannabidiol (CBD) was prepared in an ethanol-solutol-saline vehicle. Animals were randomly divided
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Evaluation of injection volumes for the transversus abdominis plane block in dog cadavers: a preliminary trial Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-14 Flavio A.V. Freitag; Eloisa Muehlbauer; Thalise daS. Gaio; Amanda A.M. dos Santos; Marcello Machado; Andrea Sanchez; Juan C.M. Duque
Objective To evaluate staining of nerve branches after the injection of different volumes during ultrasound-guided transversus abdominis plane (TAP) block in dog cadavers. Study design Prospective randomized study. Animals A total of 15 frozen/thawed adult dog cadavers. Methods Hemiabdomens were randomly allocated to one of four groups. In groups G0.3, G0.6 and G1.0, ropivacaine–methylene blue solution
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Comparison between two approaches for the transversus abdominis plane block in canine cadavers Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-10 Marta Romano; Diego A. Portela; Alexander Thomson; Pablo E. Otero
Objective To compare the dye distribution following either two lateral abdominal or one lateral abdominal and one subcostal ultrasound-guided transversus abdominis plane (TAP) injections of a clinically relevant volume of dye solution in dogs. Study design Randomized cadaveric study. Animals A total of eight canine cadavers. Methods On one side of each cadaver, two TAP injections were performed on
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Comparison of cardiopulmonary effects of etorphine and thiafentanil administered as sole agents for immobilization of impala (Aepyceros melampus) Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-10-03 Silke Pfitzer; Leith Meyer; Liesel Laubscher; Kristin Warren; Rebecca Vaughan-Higgins; Jacobus P. Raath; Michael Laurence
Objective To compare the cardiopulmonary effects of the opioids etorphine and thiafentanil for immobilization of impala. Study design Two-way crossover, randomized study. Animals A group of eight adult female impala. Methods Impala were given two treatments: 0.09 mg kg–1 etorphine or 0.09 mg kg–1 thiafentanil via remote dart injection. Time to recumbency, quality of immobilization and recovery were
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Evaluation of chemical restraint, isoflurane anesthesia and methadone or tramadol as preventive analgesia in spotted pacas (Cuniculus paca) subjected to laparoscopy Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-21 Ricardo AR. Uscategui; Felipe FPC. Barros; Vívian T. Almeida; Aline E. Kawanami; Marcus AR. Feliciano; Wilter RR. Vicente
Objective To evaluate the efficacy and cardiopulmonary effects of ketamine–midazolam for chemical restraint, isoflurane anesthesia and tramadol or methadone as preventive analgesia in spotted pacas subjected to laparoscopy. Study design Prospective placebo-controlled blinded trial. Animals A total of eight captive female Cuniculus paca weighing 9.3 ± 0.9 kg. Methods Animals were anesthetized on three
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Evaluation of tumescent local anesthesia in cats undergoing unilateral mastectomy Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-15 Clarissa MR. Moreira; Renato LS. Oliveira; Gilberto A. Costa; Katia B. Corgozinho; Stelio PL. Luna; Heloisa JM. Souza
Objective To evaluate the analgesic efficacy and safety of tumescent local anesthesia (TLA) in cats undergoing unilateral mastectomy. Study design Prospective clinical trial. Animals A total of 12 ovariohysterectomized female cats. Methods All animals were premedicated with pethidine (4 mg kg–1) intramuscularly (IM), followed by induction of anesthesia with propofol (5 mg kg–1) intravenously and maintenance
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Comparison of some cardiopulmonary effects of etorphine and thiafentanil during the chemical immobilization of blesbok (Damaliscus pygargus phillipsi) Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-11 Silke Pfitzer; Leith Meyer; Liesel Laubscher; Kristin Warren; Rebecca Vaughan-Higgins; Jacobus P. Raath; Michael Laurence
Objective To determine the cardiopulmonary effects of etorphine and thiafentanil for immobilization of blesbok. Study design Blinded, randomized, two-way crossover study. Animals A group of eight adult female blesbok. Methods Animals were immobilized twice, once with etorphine (0.09 mg kg–1) and once with thiafentanil (0.09 mg kg–1) administered intramuscularly by dart. Immobilization quality was assessed
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The effects of maxillary nerve block, ethmoidal nerve block and their combination on cardiopulmonary responses to nasal stimulation in anesthetized Beagle dogs Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-08 Hyunseok Kim; Min Jang; Chi Won Shin; Hyungjoo Han; Jeesoo Cha; Inhyung Lee; Won-gyun Son
Objective To describe an approach for ethmoidal nerve block (EBLOCK) and to compare the effects of a maxillary nerve block (MBLOCK), EBLOCK and their combination (M-EBLOCK) on heart rate (HR), systolic (SAP), mean (MAP), diastolic (DAP) arterial pressures and respiratory rate (fR) during nasal stimulation in dogs. Study design Prospective, blinded, randomized, crossover placebo-controlled study. Animals
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CEPEF4: update and plan. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-09-01 Miguel Gozalo-Marcilla,Jose I Redondo,Mark Johnston,Polly Taylor,Regula Bettschart-Wolfensberger
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Accuracy of fluid infusion pumps using different administration sets: preliminary observations. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-28 Ilaria Petruccione,Pamela J Murison
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Evaluation of nalbuphine, butorphanol and morphine in dogs during ovariohysterectomy and on early postoperative pain. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-13 Viviane H Gomes,Daniele de J Barbosa,Amanda Sda Motta,Clarice G Corrêa,Duque Jc Moreno,Marta Fa da Silva
Objective To evaluate the effects of nalbuphine, butorphanol and morphine combined with acepromazine on intraoperative and early postoperative pain management in dogs anesthetized for ovariohysterectomy. Study design Prospective, randomized blinded clinical study. Animals A total of 48 healthy female dogs of different breeds, aged 1–6 years, weighing (mean ± standard deviation) 14.5 ± 4.8 kg. Methods
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A novel ultrasound-guided lateral quadratus lumborum block in dogs: a comparative cadaveric study of two approaches Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-13 Marta Garbin; Diego A. Portela; Gianluca Bertolizio; Aitor Gallastegui; Pablo E. Otero
Objective To describe an ultrasound-guided lateral quadratus lumborum (LQL) block technique and the spread characteristics of lidocaine–dye injected in the LQL plane using a transversal (LQL-T) or a longitudinal (LQL-L) approach. Study design Experimental anatomic study. Animals A total of eight canine cadavers. Methods Bilateral ultrasound-guided injections in the fascial plane lateral to the quadratus
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Effects of intracoelomic alfaxalone-dexmedetomidine on righting reflex in common garter snakes (Thamnophis sirtalis): preliminary data. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-13 Kelly Chen,Stephanie Keating,Danielle Strahl-Heldreth,Stuart Clark-Price
Objective To evaluate the effect of dexmedetomidine on alfaxalone immobilization in snakes. Study design Nonblinded, crossover study. Animals A total of eight mature common garter snakes (Thamnophis sirtalis). Methods Snakes were administered each of three treatments intracoelomically: alfaxalone (30 mg kg–1; treatment A), alfaxalone (30 mg kg–1) combined with dexmedetomidine (0.05 mg kg–1; treatment
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Anesthetic effects of ketamine-medetomidine-hydromorphone in dogs during high-quality, high-volume surgical sterilization program under field conditions. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-12 François R Sylvestre,Beatriz P Monteiro,Marie-Josée Simard,Paulo V Steagall
Objective To describe the anesthetic and adverse effects of an injectable anesthetic protocol in dogs as part of a high-volume sterilization program under field conditions in Belize. Study design Prospective, observational, field study. Animals A total of 23 female and eight male dogs (14.2 ± 7.7 kg; age ≥ 8 weeks). Methods Using a volume per kg-based dose chart, dogs were administered ketamine (4
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Evaluation of a regional nerve block with an experimental formulation of encapsulated lidocaine in sheep. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-12 Erika A Militana,Luis Campoy,Manuel Martin-Flores,Robin D Gleed
Objective To compare the duration of nociceptive and proprioceptive blockade from an experimental encapsulated lidocaine preparation with that of conventional lidocaine. Study design Prospective, blinded, randomly assigned, crossover study. Animals A total of six adult Dorset ewes, American Society of Anesthesiologists physical status I or II, weighing 60.4 ± 18.0 kg (mean ± standard deviation). Methods
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Evaluation of analgesic, sympathetic and motor effects of 1% and 2% lidocaine administered epidurally in dogs undergoing ovariohysterectomy. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-07 Pablo Nejamkin,Florencia Landivar,María Clausse,Matías Lorenzutti,Verónica Cavilla,Verónica Gutierrez,Paula Viviani,María Del Sole,Manuel Martin-Flores
Objective To compare, versus a control, the sensory, sympathetic and motor blockade of lidocaine 1% and 2% administered epidurally in bitches undergoing ovariohysterectomy. Study design Randomized, blinded, controlled clinical trial. Animals A total of 24 mixed-breed intact female dogs. Methods All dogs were administered dexmedetomidine, tramadol and meloxicam prior to general anesthesia with midazolam–propofol
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Equine uridine diphospho-glucuronosyltransferase 1A1, 2A1, 2B4, 2B31: cDNA cloning, expression and initial characterization of morphine metabolism. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-08-04 Briana D Hamamoto-Hardman,Russell W Baden,Dan S McKemie,Heather K Knych
Objective Uridine diphospho-glucuronosyltransferases (UGTs) are membrane-bound enzymes that catalyze the conjugation of glucuronic acid onto a diverse set of xenobiotics. Horses efficiently and extensively glucuronidate a number of xenobiotics, including opioids, making UGTs an important group of drug-metabolizing enzymes for the clearance of drugs. Recombinant enzymes have allowed researchers to characterize
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Sedative effects and pharmacokinetics of detomidine when administered intravenously and intravaginally as a gel in alpacas. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-07-27 Natalie S Chow,Reza Seddighi,Heather K Knych,Xiacun Sun,Thomas J Doherty
Objectives To evaluate the sedative effects and pharmacokinetics of detomidine gel administered intravaginally to alpacas in comparison with intravenously (IV) administered detomidine. Study design Randomized, crossover, blinded experiment. Animals A group of six healthy adult female Huacaya alpacas (70.3 ± 7.9 kg). Methods Alpacas were studied on two occasions separated by ≥5 days. Treatments were
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Comparison of the effects of methadone and butorphanol combined with acepromazine for canine gastroduodenoscopy Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-07-27 Kati Maria Salla; Jaan Lepajoe; Marcus Vinicius Candido; Thomas Spillmann; Daniela Casoni
Objective To evaluate the feasibility of gastroduodenoscopy in dogs premedicated with acepromazine in combination with butorphanol or methadone. Study design Prospective, randomized, double-blinded clinical trial. Animals A group of 40 client-owned dogs. Methods Dogs were randomly allocated to one of two groups and give intramuscular acepromazine 0.02 mg kg–1 combined with either butorphanol 0.3 mg
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A retrospective evaluation of the effect of perianesthetic hydromorphone administration on the incidence of postanesthetic signs of colic in horses. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-07-23 Heather Skrzypczak,Rachel Reed,Michele Barletta,Jane Quandt,Daniel Sakai
Objective To describe the incidence of postanesthetic signs of colic (PASC) in horses and determine if perianesthetic administration of hydromorphone was associated with an increased risk of PASC. Study design Retrospective, cohort study. Animals A total of 409 horses. Methods Anesthesia and clinical records of horses admitted for various procedures from July 2018 to September 2019 were reviewed. Signs
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Cardiovascular effects of increasing dosages of norepinephrine in healthy isoflurane-anesthetized New Zealand White rabbits. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-07-17 Olivia Uccello,Andrea Sanchez,Alexander Valverde,Hugues Beaufrère
Objective To characterize the cardiovascular effects of increasing dosages of norepinephrine (NE) in healthy isoflurane-anesthetized rabbits. Study design Prospective experimental study. Animals A total of nine female ovariohysterectomized New Zealand White rabbits weighing 3.4 ± 0.2 kg (mean ± standard deviation). Methods Rabbits were premedicated intramuscularly with buprenorphine (0.05 mg kg–1)
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S100B protein and neuron-specific enolase as predictors of postoperative cognitive dysfunction in aged dogs: a case-control study. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-07-07 Sabrina Zbóril,André P Schmidt,Jean P Oses,Carolina D Wiener,Luis V Portela,Diogo O Souza,José O C Auler,Maria J C Carmona,Mariana S Fugita,Patricia B Flor,Silvia R G Cortopassi
Objective Postoperative cognitive dysfunction (POCD) may be related to brain injury. S100B protein and neuron-specific enolase (NSE) have been investigated as potential biochemical markers of neural cell injury in animals and humans. This study aimed to investigate the association between POCD, brain injury and serum concentrations of S100B and NSE after periodontal surgery in aged dogs. Study design
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A novel motor-sparing locoregional nerve block technique for stifle surgery in dogs. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-20 Benjamin Mc Gingold,Matthew C Milloway,Matthew J Morgan
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Analysis of teaching methods in anaesthesia in the undergraduate curriculum of four veterinary universities. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-14 Olivia D'Anselme,Ludovic Pelligand,Kata Veres-Nyeki,Andrea Zaccagnini,Luca Zilberstein
Objective To design a holistic audit tool to assess the effectiveness of anaesthesia teaching strategies, and thereby to study veterinary undergraduate teaching methods in different geographical areas. Study design Qualitative study using interviews of university staff and students to identify common themes and differences in teaching veterinary anaesthesia. Methods An audit was performed using an
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Field anaesthesia of Eurasian red squirrels (Sciurus vulgaris). Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-11 Anna-Katarina Schilling,Peter Ww Lurz,Anna L Meredith
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Effects of intramuscular vatinoxan (MK-467), co-administered with medetomidine and butorphanol, on cardiopulmonary and anaesthetic effects of intravenous ketamine in dogs. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-11 Heta Turunen,Marja Raekallio,Juhana Honkavaara,Johanna Jaakkola,Mika Scheinin,Sofia Männikkö,Heidi Hautajärvi,Rachel Bennett,Outi Vainio
Objective To investigate the impact of intramuscular (IM) co-administration of the peripheral α2-adrenoceptor agonist vatinoxan (MK-467) with medetomidine and butorphanol prior to intravenous (IV) ketamine on the cardiopulmonary and anaesthetic effects in dogs, followed by atipamezole reversal. Study design Randomized, masked crossover study. Animals A total of eight purpose-bred Beagle dogs aged 3
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Preliminary survey of the attitudes of Brazilian scientists towards pain management and assessment in animals used in science. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-10 Rubia M Tomacheuski,Marilda O Taffarel,Marcos Ferrante,Stelio Pl Luna
Objective To investigate the current scenario in Brazil regarding pain assessment and control in experimental animals. Study design Prospective survey. Methods A confidential questionnaire was available online and sent by e-mail to Brazilian scientists working with animal experimentation in Brazil. Data collection was conducted from October 2016 to October 2017. The exclusion criteria included blank
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A low-cost portable simulator of a domestic cat larynx for teaching endotracheal intubation. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-05 Maria Clausse,Pablo Nejamkin,Carlos A Bulant,Ariel Genaro,Florencia Landivar,María J Del Sole,Alejandro Clausse
Objective To design and construct an affordable simulator of the cat larynx for training intubation maneuvers and to share the designs for its fabrication. Study design Research and development study. Animals A domestic cat. Methods The cadaver of a cat, dead by natural causes, was frozen in sternal recumbency with the neck extended and the mouth wide open. A computed tomography image was acquired
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Effect of non-steroidal anti-inflammatory drugs on glomerular filtration rate and urinary N-acetyl-β-D-glucosaminidase activity in cats after dental surgery. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-06-03 Kavitha Kongara,Nick Cave,Karin Weidgraaf,Venkata Sayoji Rao Dukkipati
Objective To compare the effects of meloxicam or carprofen on glomerular filtration rate (GFR), and to evaluate the effect of meloxicam on urinary N-acetyl-β-D-glucosaminidase (NAG) activity, of cats after dental surgery. Study design Randomized, blinded, controlled trial. Animals A total of 24 mixed breed cats. Methods Cats were randomly assigned to one of three groups (n = 8 per group): meloxicam
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Opioid-free total intravenous anesthesia with bilateral ultrasound-guided erector spinae plane block for perioperative pain control in a dog undergoing dorsal hemilaminectomy. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-05-29 Daniel Zannin,Luciano J Isaka,Rafael H Pereira,Rodrigo Mencalha
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Evaluation of injectate distribution after ultrasound-guided peribulbar injections in canine cadavers. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-05-29 Stephan Mahler,Eric Betti,Claude Guintard
Objective To describe a contrast medium distribution pattern after peribulbar injection in cadavers. Study design A cadaveric study. Animals A group of eight male dogs and four canine cadaver heads. Methods In phase 1, ultrasound-guided peribulbar injections (1.0 mL dye) were performed in four orbits using a subzygomatic approach. After dissection, the procedure was considered successful if 1) no dye
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Hypoventilation following oxygen administration associated with alfaxalone-dexmedetomidine-midazolam anesthesia in New Zealand White rabbits. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-05-29 Frédérik Rousseau-Blass,Daniel Sj Pang
Objective To investigate the relationship between oxygen administration and ventilation in rabbits administered intramuscular alfaxalone–dexmedetomidine–midazolam. Study design Prospective, randomized, blinded study. Animals A total of 25 New Zealand White rabbits, weighing 3.1–5.9 kg and aged 1 year. Methods Rabbits were anesthetized with intramuscular alfaxalone (4 mg kg–1), dexmedetomidine (0.1
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Use of distal radial, ulnar, median and musculocutaneous (RUMM) nerve blocks in a Huacaya alpaca undergoing radial fracture repair. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-05-27 Bethany M Fackler,Diego A Portela,Marta Romano,Bonnie J Gatson
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Mirroring artefact during postoperative transversus abdominis plane (TAP) block in two dogs. Vet. Anaesth. Analg. (IF 1.368) Pub Date : 2020-05-23 Marta Romano,Diego A Portela,Pablo E Otero,Alexander Thomson
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