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Optimization and comparison of ℽ-aminobutyric acid (GABA) production by LAB in soymilk using RSM and ANN models Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-02-26 Bhargavi Rayavarapu; Padmavathi Tallapragada; Usha MS
ℽ-Aminobutyric acid (GABA) is a non-proteinaceous amino acid. In the mammalian nervous system, GABA functions as an inhibitory neurotransmitter. The present study focused on screening and optimization of ℽ-aminobutyric acid (GABA) yield by lactic acid bacteria by using soymilk as basal media. Lactobacillus fermentum (Lb. fermentum) was isolated from sourdough. The qualitative confirmation of GABA production
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Characterization, antioxidant, and cytotoxic effects of some Egyptian wild plant extracts Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-02-17 Thoria A. Diab; Thoria K. Donia; Khalil M. Saad-Allah
Natural products from plants are very safe as compared to synthetic ones, so the aim of this study was to assess the in vitro antioxidant and antitumor activities of the ethanolic extracts of four Egyptian wild plant species (Varthemia candicans, Peganum harmala, Suaeda vermiculata, and Conyza dioscoridis), as well as polyphenols and flavonoid contents with gas chromatography–mass spectrometry (GC-MS)
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Anticancer activities of phenolic compounds from Moringa oleifera leaves: in vitro and in silico mechanistic study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-02-10 Muhammad Zahid Mumtaz; Fareeda Kausar; Mubashir Hassan; Shaista Javaid; Arif Malik
Moringa oleifera is a common vegetable in many countries since ancient times, possesses numerous phenolic compounds having a wide array of biological activities. It possesses anticancer activity that can be used to develop new drugs for treatment of various types of cancers. The current study was conducted to evaluate the composition of phenolic compounds and in vitro and in silico anticancer activities
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Mutational hotspots and conserved domains of SARS-CoV-2 genome in African population Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-02-04 Olabode E. Omotoso; Ayoade D. Babalola; Amira Matareek
Since outbreak in December 2019, the highly infectious and pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over a million deaths globally. With increasing burden, the novel coronavirus has posed a dire threat to public health, social interaction, and global economy. Mutations in the SARS-CoV-2 genome are moderately evolving which might have contributed to its genome
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Effect of pioglitazone, as antidiabetic agent, on atheroma regression in type 2 diabetic patients: a systematic review and meta-analysis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-02-03 Antoine Fakhry AbdelMassih; Ahmed Ashraf; Habiba-Allah Ismail; Bassant AbdelAzeim; Ihab Hany Barsoum; Shady Girgis; George Afdal; Nesrine AbdelAzeim; Peter Afdal; Esraa Menshawey; Rahma Menshawey; Kirollos Badr; Mariem Arsanyous
Pioglitazone’s role in the induction of atheroma regression in diabetics was suggested by several RCT. The aim of our study was to evaluate this role through a systematic review of all RCT conducted on this subject. Literature was searched for relevant studies. We included all RCT that compared pioglitazone versus other antidiabetic agents. Mean differences of either AV or CIMT, HbA1C, HDL, and LDL
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Virtual screening of phytochemical compounds as potential inhibitors against SARS-CoV-2 infection Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-28 Ram Kothandan; Cashlin Anna Suveetha Gnana Rajan; Janamitra Arjun; Rejoe Raymond Michael Raj; Sowfia Syed
The present pandemic situation due to coronavirus has led to the search for newer prevention, diagnostic, and treatment methods. The onset of the corona infection in a human results in acute respiratory illness followed by death if not diagnosed and treated with suitable antiretroviral drugs. With the unavailability of the targeted drug treatment, several repurposed drugs are being used for treatment
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Isolation and optimized production of putative antimicrobial compounds from Egyptian soil isolate Streptomyces sp. MS. 10 Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-23 Mohamed Sebak; Amal E. Saafan; Sameh Abdelghani; Walid Bakeer; Abeer S. Moawad; Ahmed O. El-Gendy
The rapid spread of antibiotic resistance has increased research interest in the discovery of natural products, mainly from actinomycetes, which have been the primary source of antimicrobial compounds. This study aimed to isolate, characterize, and optimize the production of some of the bioactive compounds from bioactive soil actinomycetes. One promising soil actinomycete, which was molecularly identified
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Diterpenoids as potential anti-malarial compounds from Andrographis paniculata Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-23 Manish Kumar Dwivedi; Shringika Mishra; Shruti Sonter; Prashant Kumar Singh
The objectives of the current study are to evaluate the traditionally used medicinal plants Andrographis paniculata for in vitro anti-malarial activity against human malarial parasite Plasmodium falciparum and to further characterize the anti-malarial active extract of A. paniculata using spectroscopic and chromatographic methods. The chloroform extract of A. paniculata displayed anti-malarial activity
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Characterization of squalene synthase gene from Gymnema sylvestre R. Br. Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-15 Kuldeepsingh A. Kalariya; Ram Prasnna Meena; Lipi Poojara; Deepa Shahi; Sandip Patel
Squalene synthase (SQS) is a rate-limiting enzyme necessary to produce pentacyclic triterpenes in plants. It is an important enzyme producing squalene molecules required to run steroidal and triterpenoid biosynthesis pathways working in competitive inhibition mode. Reports are available on information pertaining to SQS gene in several plants, but detailed information on SQS gene in Gymnema sylvestre
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Analysis of structures, functions, and transgenicity of phytopeptides defensin and thionin: a review Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-14 Sarfuddin Azmi; Mohd Kamil Hussain
Antimicrobial peptides are very primitive innate defense molecules of almost all organisms, from microbes to mammalians and vascular seed-bearing plants. Antimicrobial peptides of plants categorized into cysteine-rich peptides (CRPs) and others and most of the antimicrobial peptides belong to CRPs group. These peptides reported showing the great extent of protecting property against bacteria, fungi
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Endothelial dysfunction and body mass index: is there a role for plasma peroxynitrite? Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-14 Theresa Chikopela; Douglas C. Heimburger; Longa Kaluba; Pharaoh Hamambulu; Newton Simfukwe; Wilbroad Mutale; John R. Koethe; Fastone Goma
Endothelial function is dependent on the balance between vasoconstrictive and vasodilatory substances. The endothelium ability to produce nitric oxide is one of the most crucial mechanisms in regulating vascular tone. An increase in inducible nitric oxide synthase contributes to endothelial dysfunction in overweight persons, while oxidative stress contributes to the conversion of nitric oxide to peroxynitrite
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New lipase-producing Streptomyces isolated from halo-alkaline habitat in Wadi El Natrun: polyphasic identification and statistical optimization of enzyme production Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-14 Mohamed A. Mohamed; Hassan M. Awad
Bioprospecting lipase producers in non-conventional habitats are the way to find special enzymes of diverse applications. Halo-alkaline marshes in Wadi El Natrun in Egypt are some of the most stable ecological systems in the world, and because of the double extremities of alkalinity and salinity, they harbor individual microbes capable of adapting stress conditions. Eight strains were recovered from
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Chemical profiling of selected Ayurveda formulations recommended for COVID-19 Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-11 Sulaiman C. T.; Deepak M.; Ramesh P. R.; Mahesh K.; Anandan E. M.; Indira Balachandran
The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the global health concern since December 2019. It has become a big challenge for the researchers to find a solution for this newly evolved pandemic. In Ayurveda point of view, COVID-19 is a Janapadodhwamsa vikara (epidemic disease), a situation where the environment—air, water
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Biosynthesis, characterization, and antibacterial activity of ZnO nanoaggregates using aqueous extract from Anacardium occidentale leaf: comparative study of different precursors Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2021-01-06 Eric Kwabena Droepenu; Ebenezer Aquisman Asare; Boon Siong Wee; Rafeah Binti Wahi; Frederick Ayertey; Michael Odoi Kyene
Various parts of Anacardium occidentale plant possess curative qualities like antidiabetic, anti-inflammatory, antibacterial, antifungal, and antioxidant. Aqueous extract of this plant leaf was used in biosynthesizing zinc oxide (ZnO) nanoaggregates using two precursors of zinc salt (zinc acetate dihydrate [Zn(CH3COO)2∙2H2O] and zinc chloride [ZnCl2]). The synthesized ZnO samples were used in a comparative
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Elevation of gene expression of Btg2, Gadd 153, and antioxidant markers in RONS-induced PC12 cells Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-28 Aravind P; Sarojini R. Bulbule; Hemalatha N; Anushree G; Babu R.L; Devaraju K.S
Free radicals generated in the biological system bring about modifications in biological molecules causing damage to their structure and function. Identifying the damage caused by ROS and RNS is important to predict the pathway of apoptosis due to stress in PC12 cells. The first defense mechanisms against them are antioxidants which act in various pathways through important cellular organelles like
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Effect of epigallocatechin gallate on aluminum chloride-induced changes in behavior, biochemical parameters, and spermatogenesis of Sprague-Dawley rats Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-21 Subramani Parasuraman; Brenda Ngu Yen Qin; Lam Chew Hui; James Yu Kar Beng
Epigallocatechin gallate (EGCG) acts as an antioxidant by preventing oxidative stress. The effect of EGCG on aluminum-induced testicular injury is not clear. Hence, the present study is planned to investigate the effect of EGCG on aluminum chloride (AlCl3)-induced changes in behavior, biochemical parameters, and spermatogenesis in male Sprague-Dawley rats. The rats were divided into six groups with
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Molecular mechanisms and the vital roles of resistin, TLR 4, and NF-κB in treating type 2 diabetic complications Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-17 Venkataiah Gudise; Bimalendu Chowdhury
Type 2 diabetes in obese (≥ 25 and ≥ 30 kg/m2) patients is the foremost cause of cardiovascular complications like stroke, osteoarthritis, cancers (endometrial, breast, ovarian, liver, kidney, colon, and prostate), and vascular complications like diabetic neuropathy, diabetic and retinopathy, and diabetic nephropathy. It is recognized as a global burden disorder with high prevalence in middle-income
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Assessing the nanotechnology on the grounds of costs, benefits, and risks Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-10 Garima Pandey; Pallavi Jain
The technical innovations are based on the principles of science with the assurance of outweighing their cost and risk factors with the benefits to society. But sometimes, the innovation either itself becomes a risk or brings in some risk factors along with it. For most of the alleyway of an innovation from its emergence to its road to societal acceptance and adoption, the focus remains on the benefits
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Quantitative structure-activity relationship, molecular docking, drug-likeness, and pharmacokinetic studies of some non-small cell lung cancer therapeutic agents Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-10 Muhammad Tukur Ibrahim; Adamu Uzairu; Sani Uba; Gideon Adamu Shallangwa
Lung cancer has been reported to be among the leading cancer cases in the world. It was also reported to have caused a lot of death every year and accounted for about one-third of the whole cancer deaths in the globe. The main subset of lung cancers that accounts for about 85% of the problems of lung cancer raised above was non-small cell lung cancer (NSCLC). The most common cause of NSCLCs that mostly
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Most promising solid dispersion technique of oral dispersible tablet Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-09 Vikrant K. Nikam; Shubham K. Shete; Jyoti P. Khapare
The most common problem about conventional dosage form is dysphagia (difficulty in swallowing). So, we design a new approach in a conventional dosage form which is oral dispersible tablet. Oral dispersible tablet is also called as mouth dissolving tablet, fast dissolving tablet, or oral disintegrating tablet. Oral dispersible tablet has advantage as it quickly disintegrates into saliva when it is put
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Molecular identification and antimicrobial activity of endophytic fungi isolated from Heritiera fomes (Buch. -Ham), a mangrove plant of the Sundarbans Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-09 Tauhidur Rahman Nurunnabi; Sabiha Sarwar; Farah Sabrin; Farzana Alam; Lutfun Nahar; Hossain Sohrab; Satyajit D. Sarker; S. M. Mahbubur Rahman; Morsaline Billah
Endophytic fungi play a vital role in plant defense system by secreting various antimicrobial agents. To evaluate the antimicrobial activity of the endophytic fungi of the mangrove plant Heritiera fomes (Buch. -Ham), plants were collected from the Sundarbans, Bangladesh. The endophytic fungi were subsequently isolated and identified. Fifty-five endophytic fungi were isolated from the leaves, root,
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Psidium guajava leaves assisted green synthesis of metallic nanoparticles: a review Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-03 Shriniwas P. Patil; Pradip M. Rane
Several attempts have been made for green synthesis of metallic nanoparticles, revealing the significance of plant extracts in reducing metal source to nanoparticles and applications in various domains of science. Psidium guajava (guava) is evergreen, edible fruit-bearing plant, belonging to family Myrtaceae. Its leaves are reported to contain several phytochemicals like tannins, glycosides, terpenes
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Improved biodiesel from palm oil using lipase immobilized calcium alginate and Irvingia gabonensis matrices Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-03 Sarafadeen Olateju Kareem; Esther Imole Falokun; Saka Adebayo Balogun; Oluwaseyi A. Akinloye; Sunday Osaizua Omeike
Lipase is an important microbial enzyme and biocatalyst in biodiesel production. The study investigated fuel properties of biodiesel produced from palm oil (PO) using lipase immobilized on Irvingia gabonensis and calcium alginate. Biodiesel yield from PO using free and immobilized lipases was highest at 35 °C and pH 7, with product yield using calcium alginate-immobilized lipase, CAIL (94.42, 96.9%)
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Histological, ultrastructural, and biochemical study on the possible role of Panax ginseng in ameliorating liver injury induced by Lambda cyhalotherin Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-12-03 Manal Abdul-Hamid; Hanaa M. Mohamed; Sanaa M. Abd El-Twab; Karim Zaied
Lambda-cyhalotherin (LCT) is a pyrithroid type 2 pesticide that is broadly utilized in pest control in public health, animal health, and agriculture. Although claiming that LCT has a low mammalian toxicity, several investigations reported its mammalian hepatotoxicity by mediating oxidative stress causes severe hepatotoxicity and liver damage. LCT significantly decreased catalase (CAT), superoxide dismutase
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Rational in silico drug design of HIV-RT inhibitors through G-QSAR and molecular docking study of 4-arylthio and 4-aryloxy-3-iodopyridine-2(1-H)-one derivative Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-30 Debadash Panigrahi; Amiyakanta Mishra; Susanta Kumar Sahu
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Antiretroviral therapy (ART) against HIV infection offers the promise of controlling disease progression and prolonging the survival of HIV-infected patients. Reverse transcriptase (RT) inhibitors remain the cornerstone
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Effect of dietary supplementation of seaweed (Ulva lactuca) and Azolla on growth performance, haematological and serum biochemical parameters of Aseel chicken Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-26 Vijayalingam Thavasi Alagan; Rajesh Nakulan Vatsala; Ilavarasan Sagadevan; Vairamuthu Subbiah; Venkataramanan Ragothaman
An effort was made to assess the effectiveness of dietary supplementation of Ulva lactuca (U. lactuca), a seaweed and Azolla individually and in combination on different physiological parameters of Aseel chicken. A total of 40 Aseel chicks of 8 weeks old were allocated into four groups, C1 (control), T1 (Azolla alone), T2 (seaweed alone) and T3 (seaweed plus Azolla). Aseel chicks in C1 were fed with
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An overview of recent progress in modern synthetic approach—combinatorial synthesis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-26 Chandravadivelu Gopi; Gudapati Krupamai; Chitikina Satya Sri; Magharla Dasaratha Dhanaraju
In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small set up of reactions between different building blocks using solid-phase and solution-phase techniques. This method reduced the time and cost of the drug discovery process substantially. Thousands of compounds are synthesised in a few reactions through combinatorial
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Biosynthesis, characterization, and in vitro assessment on cytotoxicity of actinomycete-synthesized silver nanoparticles on Allium cepa root tip cells Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-24 Sreenivasa Nayaka; Bidhayak Chakraborty; Meghashyama Prabhakara Bhat; Shashiraj Kareyallappa Nagaraja; Dattatraya Airodagi; Pallavi Sathyanarayana Swamy; Muthuraj Rudrappa; Halaswamy Hiremath; Dhanyakumara Shivapoojar Basavarajappa; Bharati Kanakannanavar
The industrial production of silver nanoparticles (AgNPs) and its commercial applications are being considerably increased in recent times, resulting in the release of AgNPs in the environment and enhanced probability of contaminations and their adverse effects on living systems. Based on this, the present study was conducted to evaluate the in vitro cytotoxicity of actinomycete-synthesized AgNPs on
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Molecular docking and QSAR theoretical model for prediction of phthalazinone derivatives as new class of potent dengue virus inhibitors Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-17 Samuel Ndaghiya Adawara; Gideon Adamu Shallangwa; Paul Andrew Mamza; Abdulkadir Ibrahim
Dengue fever is a key public health unease in various tropical and sub-tropical regions. The improvement of existing agents that can inhibit the dengue virus is therefore of utmost importance. In this work, the QSAR study was carried out on 25 molecules of phthalazinone derivatives which have been reported to possess excellent dengue virus inhibitory activity. Density functional computational technique
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Accelerate disaster risk mapping using an automated zonal change detection model for loss estimation and recovery: a flood case study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-11 Ali Amasha
The flash flood still constitutes one of the major natural meteorological disasters harmfully threatening local communities, that creates life losses and destroying infrastructures. The severity and magnitude of disasters always reflected from the size of impacts. Most of the conventional research models related to flooding vulnerability are focusing on hydro-meteorological and morphometric measurements
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Exploring the potential of using bioactive plant products in the management of Fusarium oxysporum f.sp. albedinis: the causal agent of Bayoud disease on date palm (Phoenix dactylifera L.) Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-10 Eimad Dine Tariq Bouhlali; Mgal Derouich; Houria Ben-Amar; Reda Meziani; Adil Essarioui
“Bayoud” disease caused by Fusarium oxysporum f. sp. albedinis (Foa) poses a serious threat to date palm (Phoenix dactylifera L.) in Morocco. However, research studies performed to discover biological methods to control this disease remain limited. The present study has set objectives to determine antifungal activity of five plants extracts (Acacia cyanophylla, Cupressus atlantica, Eucalyptus torquata
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Improved model predictive load frequency control of interconnected power system with synchronized automatic generation control loops Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-11-03 Abdullahi Bala Kunya; Mehmet Argin; Yusuf Jibril; Yusuf Abubakar Shaaban
Automatic generation control (AGC) of multi-area interconnected power system (IPS) is often designed with negligible cross-coupling between the load frequency control (LFC) and automatic voltage regulation (AVR) loops. This is because the AVR loop is considerably faster than that of LFC. However, with the introduction of slow optimal control action on the AVR, positive damping effect can be achieved
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Microbacterium sp. MRS-1, a potential bacterium for cobalt reduction and synthesis of less/non-toxic cobalt oxide nanoparticles (Co3O4) Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-10-27 Sathyavathi Sundararaju; Manjula Arumugam; Prakash Bhuyar
Detoxification of heavy metal pollutants in wastewater has become a serious problem to surrounding environment. This research was conducted to utilize a potential heavy metal-resistant bacterium for the remediation of cobalt metal and simultaneous synthesis of cobalt oxide nanoparticles in the form of powder for various industrial applications. Metal oxide nanoparticles have great applications in electrochemical
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Antiglycaemic potentials and molecular docking studies of the extracts of Cassia alata L. Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-10-20 Babatunde Joseph Oso; Ige Francis Olaoye
This study assessed the antiglycaemic properties of the methanolic extracts of the dried leaf of Cassia alata L. through in vitro and in silico approaches. The methanolic crude extract (MCE) of the dried leaf was prepared and partitioned into n-butanol (BPE) and aqueous (ARE) extracts. The antiglycaemic potential was assessed in vitro by studying the inhibitory actions of the extracts with α-amylase
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Identification of suitable substitute for Sarpagandha (Rauvolfia serpentina (L.) Benth. ex Kurz) by phytochemical and pharmacological evaluation Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-10-13 Sulaiman C. T.; Jyothi C.K.; Jinu Krishnan Unnithan; Prabhukumar K.M.; Indira Balachandran
Sarpagandha is an important Ayurveda drug used for treating many diseases including high blood pressure. Rauvolfia serpentina is the genuine source plant for Sarpagandha and it is a critically endangered species belonging to the family Apocynaceae. The present study is aimed at finding out an appropriate substitute for the endangered species R. serpentina by evaluating the phytochemistry and biological
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Messenger RNA (mRNA)-based age determination using skin-specific markers of saliva epithelial cells Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-10-08 Onyekachi Ogbonnaya Iroanya; Josephine Chioma Obi; Olabisi Olanike Ogunyinka; Oluwayomi Temidayo Bosede; Tochukwu Frank Egwuatu; Richard Adeniyi Adewole
Age determination is a vital factor in biological identification in forensics. This study was carried out to determine the expression levels of three target genes (Keratin 9 (KRT9), Loricrin (LOR) and Corneodesmosin (CDSN)) in salivary epithelial cells and how they can be used in age determination using reference gene, β-actin. Thirty young adults participated in the study and were divided into three
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Effect of an oscillating time-dependent pressure gradient on Dean flow: transient solution Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-10-06 Basant K. Jha; Dauda Gambo
Navier-Stokes and continuity equations are utilized to simulate fully developed laminar Dean flow with an oscillating time-dependent pressure gradient. These equations are solved analytically with the appropriate boundary and initial conditions in terms of Laplace domain and inverted to time domain using a numerical inversion technique known as Riemann-Sum Approximation (RSA). The flow is assumed to
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Flavonoids: isolation, characterization, and health benefits Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-09-29 Abiche Ekalu; James Dama Habila
The unique and vast pharmacological activities of flavonoids have made them of research interest. This led to the use of various techniques to isolate and characterize them, intending to determine their potential health benefits. The medicinal values of plant-based flavonoids that this literature review tends to summarize the pharmacological activities of these secondary metabolites from 22 selected
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Performance and evaluation of energy optimization techniques for wireless body area networks Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-09-22 Naveen Bilandi; Harsh Kumar Verma; Renu Dhir
Wireless body area networks are created to retrieve and transmit human health information by using sensors on the human body. Energy efficiency is considered a foremost challenge to increase the lifetime of a network. To deal with energy efficiency, one of the important mechanisms is selecting the relay node, which can be modeled as an optimization problem. These days nature-inspired algorithms are
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A novel hydraulic fracturing gel realization for unconventional reservoirs Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-09-15 R. V. V. Ramana Murthy; Murthy Chavali
Coal bed methane reservoirs possess low to ultra-low permeability. In order to improve the production from CBM wells, stimulation techniques were deployed. This article reviews the most cost-effective, time-saving, and eco-friendly fracturing fluid which is a mix of water, guar gum, and sodium acetate. This article also provides a detailed study of hydraulic fracturing in unconventional reservoirs
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Spray drying studies of probiotic Enterococcus strains encapsulated with whey protein and maltodextrin Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-09-08 Ashlesha Bhagwat; Pravin Bhushette; Uday S. Annapure
Probiotic Enterococcus strains of human origin were microencapsulated by spray drying using whey protein and maltodextrin as an encapsulating agent. The obtained encapsulates were characterized for stability, viability, and physiological properties. The microcapsules were prepared from probiotic Enterococcus strains that were previously isolated from human vagina and infants’ meconium. The microcapsules
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Design and performance evaluation of a device for determination of specific heat capacity of thermal insulators Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-09-01 Sunday Edet Etuk; Ubong Williams Robert; Okechukwu Ebuka Agbasi
Specific heat capacity is one of the prominent and deciding factors for selection of thermal insulation materials in thermal engineering. In recent times, there has been a great advancement in the manufacturing of a variety of advanced materials in order to meet the modern needs for thermal insulation. Unfortunately, certain drawbacks like high cost of procurement, low accuracy, and limited suitability
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Antioxidant activities of some edaphic algae in Egypt Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-08-24 Neamat H. El-Tablawy; Hoda A. Mansour; Abd El-Salam M. Shaaban
Algae in general characterized by their rich content of biological compounds. However, few studies were conducted on the soil-inhabiting algae and their antioxidant characteristics. The present study was designed to evaluate the antioxidant activity of four edaphic algae including one on-soil alga (Vaucheria geminata) and three axenic isolated in-soil algae (Pleurochloris pyrenoidosa, Botrydiopsis
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In silico molecular docking studies and MM/GBSA analysis of coumarin-carbonodithioate hybrid derivatives divulge the anticancer potential against breast cancer Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-08-17 Shridhar Veeresh Pattar; Shakeel Ahamed Adhoni; Chandrappa Mukappa Kamanavalli; Suresh Sadashiv Kumbar
There are many biomarkers associated with breast cancer. Higher expression of PIK3CA (Phosphoinositide 3-kinase Cα), in its upregulated form, is associated with Hr+ and Her2− breast cancer; therefore, many drugs were synthesized against this protein to treat breast cancer patients. FDA recently approved that the drug alpelisib also inhibits PI3KCα (PDB ID-5DXT) in BC patients with Hr+ and Her2−. In
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In vivo evaluation of pharmacological properties of Argentine stingless bee geopropolis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-08-10 Ivana Y. Brodkiewicz; Marcos A. Reynoso; Nancy R. Vera
Propolis is a natural product that has been widely utilized as medicine and dietary supplement because of its broad biological activities. However, although meliponide hive products have many advantages, meliponiculture has not yet become popular in Argentina, and few scientific studies on its chemical composition and/or its bioactive properties were reported, so the use of stingless bee propolis Argentine
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Polylactic acid-based electrospun fiber and hyaluronic acid-valsartan hydrogel scaffold for chronic wound healing Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-08-10 Margaret O. Ilomuanya; Prosper S. Okafor; Joyce N. Amajuoyi; John C. Onyejekwe; Omotunde O. Okubanjo; Samson O. Adeosun; Boladale O. Silva
In this study, the chronic wound healing ability of PLA-based electrospun nanofibers loaded with hyaluronic acid, valsartan, and ascorbic acid is explored. PLA-based scaffolds were fabricated by electrospinning, followed by loading the scaffolds with different concentrations of hyaluronic acid, valsartan, and ascorbic acid hydrogels. The produced formulations were characterized by scanning electron
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Synthesis, characterization, and investigation of the anti-inflammatory effect of 2,3-disubstituted quinazoline-4(1H)-one Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-08-05 Bhimrao Ghodge; Ajay Kshirsagar; Vijay Navghare
Quinazolin-4(1H)-one nucleus has attracted the attention of medicinal chemists due to their clinical uses. Modification of quinazolinone ring for the development of pharmaceutical and clinical compound for its anti-inflammatory potential. In vitro anti-inflammatory activity of the synthesized compounds was performed by using egg albumin protein denaturation assay, while in vivo anti-inflammatory activity
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QSAR, QSTR, and molecular docking studies of the anti-proliferative activity of phenylpiperazine derivatives against DU145 prostate cancer cell lines Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-07-29 Fabian A. Ikwu; Gideon A. Shallangwa; Paul A. Mamza
Prostate cancer is the most common non-cutaneous cancer in males and accounts for about 4% of all cancer-related deaths in males annually. In silico methods provide faster, economical, and environmentally friendly alternatives to the traditional trial and error method of lead identification and optimization. This study, therefore, was aimed at building a robust QSAR and QSTR model to predict the anti-proliferate
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Kinetics and statistical analysis of the bio-stimulating effects of goat litter in crude oil biodegradation process Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-07-22 Kingsley Amechi Ani; Emmanuel Chibundo Chukwuma
The kinetics and statistical analysis of crude oil (CO) degradation in CO-contaminated soil (COCS) using goat litter (GL) were investigated. The data obtained from the CO degradation process was fitted to the first- and second-order kinetic models. The effects of process parameters such as temperature and the initial CO concentrations on the CO degradation process were also investigated. The one-way
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Isolation and characterization of an acid and metal tolerant Enterobacter cloacae NZS strain from former mining lake in Selangor, Malaysia Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-07-15 Nur Zurith Syafiqa Mazalan; Ayokunmi Oyeleye; Raja Noor Zaliha Raja Abd. Rahman; Ahmad Zaharin Aris; Abu Bakar Salleh; Yahaya M. Normi
Metal polluted environments have been found to harbor acid and metal tolerant bacterial communities. Metal oxidizing bacteria in particular are industrially important microorganisms that can be utilized for potential applications in biomining and bioremediation. However, some well-characterized strains are not readily culturable as they are obligate and fastidious chemolithotrophs requiring special
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Hazard quotient, microbial diversity, and plant composition of spent crude oil-polluted soil Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-07-08 Beckley Ikhajiagbe; Matthew Chidozie Ogwu
The present work assesses the concentration of some heavy metal, plant species composition, and microbial diversity of spent crude oil-polluted soil from electric generator plant house, auto mechanic workshop, bakery, and auto spare part shops in four local governments areas (Egor, Ikpoba-Okha, Oredo, and Ovia North) in Edo State, Southern Nigeria. Hazard quotient (HQ) of heavy metals varied in all
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The evaluation of healing effect of low-level laser treatment following gingivectomy Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-07-01 Marwa Madi; Maha M. Mahmoud
Lasers have been investigated as an alternative or adjunctive tool to conventional procedures commonly used in periodontology. The application of low-level laser therapy (LLLT) in dentistry was proposed to provide minimally invasive and painless treatment as well as increasing the comfort for the patient following surgery. Thus, the purpose of the current study was to evaluate the effect of LLLT on
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Ameliorative effect of alpha lipoic acid and royal jelly against the side effects of cyclophosphamide in liver of albino rats Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-06-29 Manal Abdul-Hamid; Nadia Moustafa; Khalid A. El-Nesr; Amal M. Abukhadra
Cyclophosphamide (CP) is a cytotoxic anticancer drug used for the treatment of neoplastic diseases. The present study aimed to examine biochemical, histological, and ultrastructural effects of CP on rat liver and determine the hepatoprotective effects of alpha-lipoic acid (LA) or royal jelly (RJ) against CP. The present study revealed that CP-induced significant increase in hepatic marker enzymes (ALT
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In silico modeling of tetraoxane-8-aminoquinoline hybrids active against Plasmodium falciparum Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-06-23 Aliyu Wappah Mahmud; Gideon Adamu Shallangwa; Adamu Uzairu
Quantitative structure-activity relationships (QSAR) is a technique that is used to produce a model that connects biological activities of compounds to their chemical structures, and molecular docking is a technique that reveals the binding mode and interactions between a drug and its target enzyme. These techniques have been successfully applied in the design and development of many drug candidates
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Potential of peel extracts of Punica granatum and Citrus aurantifolia on alloxan-induced diabetic rats Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-06-16 Sivasangari Ramya; Vijayanand Narayanan; Boomibalagan Ponnerulan; Eswaran Saminathan; Uthirapandi Veeranan
Peel is one of the major by-products in fruit processing industry. Fruit products (non-edible parts) are also considered as waste products and often discarded in the environment. Fruit peels are now serving as one of the primary sources for isolation and extraction of secondary metabolites in pharmaceutical industry. The present investigation was carried out to screen the phytochemical constituents
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Evaluated the lead levels at boiling water in clay pots and impact of the lead contaminated diet on nutritional, biochemical status of male rats Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-06-10 Mona S. El Kutry; El-Sayeda G.E. El-Sahar
For centuries, people have been using clay or earthen pots for cooking. Also, many studies indicated a contrariety from safety or danger of it. Our study aims to assess the lead concentration in boiling water in clay pots. Contaminated the diet with lead acetate and evaluated the nutritional, biochemical statues, and histological studies for male albino rats. Step A: Ten samples of the distilled water
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Morphological and molecular characterization of Setaria equina in donkeys Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-06-01 Mona Mohammed I. Abdel Rahman
Adult worms of Setaria equina mainly found in the peritoneal cavity of equine. They were nonpathogenic but might induce varied degrees of peritonitis and might migrate to the eye, brain, lung, and scrotum causing lacrimation, blindness, paraplegia, locomotor, and neurological disturbances. Identification by light microscopy is insufficient to differentiate Setaria species, and so scanning electron
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In silico studies of some 2-anilinopyrimidine derivatives as anti-triple-negative breast cancer agents Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-05-26 Hadiza Lawal Abdulrahman; Adamu Uzairu; Sani Uba
Breast cancer is a major form of health problem on the globe and the second cause of death related to cancer amidst women. A prediction of about 1 to 1.3 million cases on cancer of the breast are detected yearly globally. Triple-negative type of breast cancers (TNBCs) are described by the lack of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), and progesterone receptor (PR)
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Antioxidant, antibacterial activity, and phytochemical characterization of Carica papaya flowers Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-05-21 Manish Kumar Dwivedi; Shruti Sonter; Shringika Mishra; Digvesh Kumar Patel; Prashant Kumar Singh
Carica papaya is an eminent medicinal plant used all over the world to treat several diseases like malaria, dengue, inflammation, and skin infections. In this study, preliminary phytochemical screening for C. papaya flowers was carried out using different methods as TLC screening and UV-spectroscopy along with evaluation of antioxidant and antibacterial activities. Methods were also developed for TLC
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Solution properties and comparative antimicrobial efficacy study of different brands of toothpaste of Nepal Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2020-05-18 Narendra Kumar Chaudhary; Biswash Guragain; Reena Lamichhane-Khadka; Ajaya Bhattarai
The main objective of this study is to compare the effectiveness of toothpaste formulations in giving total protection to the oral cavity. So, three important solution properties: surface tension, conductivity, and pH measurements, have been investigated for eight kinds of commercial herbal and non-herbal based toothpaste of Nepal. The study was extended to evaluate the antibacterial efficacy of toothpaste