Using two-dimensional (2D) nickel-based metal organic framework (Ni-MOF) nanosheets as a matrix, Eu3+ and Ag+ were incorporated to synthesize Ag/Eu@Ni-MOF with double luminescence centers of Eu3+ ion (615 nm) and organic ligand (524 nm). And a ratiometric luminescence sensor is constructed based on Ag/Eu@Ni-MOF for sensitive detection of biothiols in aqueous solutions. The dual-emissive fluorescence

Mercury (Hg) causes serious health issues in its all forms. Deficiency as well as excess of copper ion (Cu2+) in human body is hazardous. A series of four compounds have been derived from carboxylated benzoic acids (benzoic acid, isophthalic acid, terephthalic acid and phthalic acid) and 4H-1,2,4 triazole-4-amine and characterized. Fluorescence detection of Hg2+ was recorded by the derivates with benzoic

Striking colorimetric probe (CynH) for abrupt detection of hydrazine under complete aqueous solution was achieved. The water soluble probe was designed with electron “push–pull” strategy by coupling of 4-hydroxy benzaldehyde and 2, 3, 3-trimethylindolinine. The positively charged N-propylated indolinine make the probe completely soluble in water. The probe yields eye catching selective detection of

Two coordination polymers, that is [Zn(pdc)(im)(H2O)]n (1) and [Cu(pdc)(im)2]n·n(H2pdc) (2) (H2pdc = terephthalic acid, im = imidazole), were hydrothermally synthesized via the reactions of H2pdc and im in combination with Zn(II) or Cu(II) ions. Compound 1 shows intense blue luminescence and compound 2 shows good photocatalytic activity for the methyl violet degradation under the irradiation of ultraviolet

The present work focuses the study of effect of solvent on third-order nonlinear optical (NLO) properties of reactive blue 19 dye dissolved in various polar solvents, namely ethanol, DMF and DMSO, respectively. Fourier Transform Infrared Spectroscopy (FT-IR) was used to find the functional groups present in reactive blue 19 dye. Third-order NLO features of reactive blue 19 dye was examined by a low

We present a method for the evaluation of fluorescence fluctuations on the basis of Mandel’s Q parameter, using sampling time-dependent factorial cumulants. By relating the Q parameter to the sampling time, we obtain the mean single molecule rate (mSMR), an easy to interpret expression that provides both brightness and diffusion information. The model is suitable for the widely used confocal setups

A chemical sensor that can induce near-infrared red-shifted response represents a promising strategy for the design and development of anion probes. In this work, novel CH-controlled colorimetric probe 3 based on anthracene carboximide was developed for near-infrared detection of cyanide. Probe 3 consisted of CHCN binding site to anthracene carboximide fluorophore, and showed a significant visual change

Lysozyme is widely used for the synthesis of nanomaterials (e.g., gold nanoparticle) to fluorescently sense metal ions. However, the effect of metal ions on the fluorescence of lysozyme is not studied yet. Herein, we have explored the interactions of lysozyme with different metal ions to develop a direct sensing platform for Fe(III). It has been observed that the fluorescence of lysozyme was slightly

A simple and novel Schiff base chemosensor (BMHM) based on benzimidazole was synthesized. In ethanol–water (1:1, v/v) medium on varying concentrations of Zn2+ chemosensor exhibited a strong and quick turn on fluorescence response. The Zn2+ recognition was based on the Chelation–enhanced fluorescence effect. The binding constant and limit of detection for BMHM-Zn2+ complexation were estimated to be

Novel alkylated heterocyclic chalcone (E)-1-(2-(allyloxy)phenyl)-3-(9-ethyl-9H-carbazol-3-yl)prop-2-en-1-one (AECO) with extended π-bond was prepared by the multi-steps synthesis. The structure of the AECO was established by the spectroscopic technics and purity of the compound was confirmed by the elemental analysis. Physicochemical parameters of the AECO such as molar absorption coefficient, transition

Recently, prenatal diagnosis with non-invasive insight is a progressive approach in clinical medicine to prevent the birth of infants with genetic abnormalities. Cell free fetal DNA (cffDNA) makes up approximately 3–6% of the bare DNA in the mother's bloodstream which is produced during pregnancy and can be used to detect fetal sex and disease in the early stages. SRY is a gene located on the chromosome

Dipyrrolydiketones BF2 complex was synthesized and characterized by NMR, HRMS, and single crystal diffraction. In non-polar environment, this BF2 containing dye emitted bright blue-green fluorescence. No significant spectra shift was observed both in absorption and emission spectra, which indicates the insensitivity of absorption/emission toward environment. The alkyl substituted pyrrole rings lead

Investigation of temperature-dependent photoluminescent properties of potassium perylene-3,4,9,10-tetracarboxylate (K4PTC), a molecule with no internal rotational degrees of freedom, shows aggregation-induced enhanced emission at room temperature. The different excitonic emission processes are dependent of temperature, some of which quenches in an intermediate temperature range (from 50 to 150 K).

The methyl orange [C14H14N3SO3Na], an azo dye exhibited strong emission and large Stokes shift in various solvents, and the largest shift (Δλ = 125.51nm or Δν = 9297cm-1) was obtained in the water. The UV-visible spectra of the dye showed the absorption in the range (33,333 – 20,000) cm-1. We found that solvent effects on the absorption wavelength are consistent. The bathochromic shift in water and

Currently, atherosclerosis accounts for the majority of cardiovascular morbidity and mortality worldwide, and predicting the stability of atherosclerotic plaque is the main method to prevent atherosclerotic death. This study aims to establish a dual-label time-resolved fluorescence immunoassay (TRFIA) of matrix metalloprotein-9 (MMP-9) and lipoprotein-associated phospholipaseA2 (Lp-PLA2) to predict

We report, to our best knowledge, the first observation of two-photon and three-photon fluorescence of Triton X-100 (TX-100) in water and cyclohexane. The observed multiphoton fluorescence (MF) falls in the ultraviolet region 280-340nm as its one photon fluorescence does. Effects of excitation wavelengths and solution concentrations on the fluorescence spectra are investigated. We found the optimal

Although cyanogen ion (CN−) plays important role in industry which also bring acute environmental pollution. More serious, trace CN− enters the human body can cause serious consequences and even death. Therefore, it is of great significance to detect trace CN− with high sensitivity. Herein, a novel aggregation-induced emission (AIE) probe C-BH was synthesized based on coumarin matrix. Probe C-BH showed

We have prepared Schiff base functionalized 1,2,4-triazole and pyrene derivative for selective, sensitive, and naked eye colorimetric detection of Cu2+ in the mixed organic- aqueous media. Amongst the 18 different metal ions studied for absorption and fluorescence titration, only Cu2+ ion encourages the modification in spectral properties of Schiff base functionalized 1,2,4-Triazole and Pyrene Probe

The mechanism of the fluorescence quenching of the CQDs by warfarin was determined and based on this study a simple, low cost and highly sensitive nanosensor was developed for determination of Warfarin in plasma samples. The carbon quantum dots with 3.5 µs lifetime (halflife of 2.4 µs) were synthesized by hydrothermal method and characterized. The fluorescence rate constant of 4.5 × 104 s−1 and quenching

A computational study based on the DFT/TD-DFT approach was performed to explore various properties of 6-aminoquinoline (6AQ). The geometrical parameters, molecular orbitals (MOs), electronic spectra, electrostatic potential, molecular surface, reactivity parameters and thermodynamic properties of 6AQ were explored. The absorption and emission spectra of 6AQ in solvents have been estimated by TD-DFT

Nanostructured fluorescent particles derived from natural molecules were prepared by a green synthesis technique employing a microwave method. The precursors citric acid (CA) and cysteine (Cys) were used in the preparation of S- and N-doped Cys carbon dots (Cys CDs). Synthesis was completed in 3 min. The graphitic structure revealed by XRD analysis of Cys CDs dots had good water dispersity, with diameters

Carbohydrate sensing in an aqueous solution remains a very challenging area of interest. Using the idea of covalent reversible interaction between boronic acids and the diol groups in carbohydrates enable us to design a carbohydrate sensor 1-thianthrenylboronic acid (1T), which has high selectivity towards fructose. To elucidate the sensing and binding properties of 1T with sugars, we have incorporated

We synthesized an original reversible colorimetric chemosensor PDJ ((E)-9-((2-(6-chloropyridazin-3-yl)hydrazono)methyl)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol) for the detection of F−. PDJ displayed a selective colorimetric detection to F− with a variation of color from colorless to yellow. Limit of detection of PDJ for F− was calculated as 12.1 µM. The binding mode of PDJ and F− turned

This paper highlights advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) as a fluorophore in design and application of fluorescent sensors for microenvironment polarity. Sections of the paper cover broad analysis of a range of fluorescent indicators immobilized in ethyl- and methyl cellulose matrices. The present study demonstrates that BODIPY-based fluorescent materials could be successfully

The present work aims to study of third-order nonlinear optical (TONLO) behavior of basic violet 3 dye dissolved in polar protic and aprotic solvents, namely, ethanol, 1-propanol, acetone and dimethyl sulfonate (DMSO), respectively. The polarity of the solvent used to have a substantial impact on the linear and TONLO properties of the dye sample. The dye exhibits self-defocusing nonlinearity due to

In spite of a rapid growth of data processing software, that has allowed for a huge advancement in many fields of chemistry, some research issues still remain problematic. A standard example of a troublesome challenge is the analysis of multi-component mixtures. The classical approach to such a problem consists of separating each component from a sample and performing individual measurements. The advent

We have constructed a novel fluorescein-based fluorescent chemosensor, FL-In, functionalised with an indole moiety and capable of sensing by both the optical "turn-on" and electrochemical detection of carbonate ions (CO32-) in aqueous media. The probe exhibits excellent selectivity and a low detection limit (0.27 µM) regarding carbonate ions by a possible coordination and hydrolysis reaction mechanism

A simple microwave-assisted synthesis of nitrogen-doped carbon dots with high oxygen content (O-N-CDs) was carried out with citric acid as a carbon source and 2,4-diamino-6-methyl-1,3,5-triazine as a nitrogen source in triethylene glycol (TEG) media. It was determined by SEM analysis that O-N-CDs consisted of particles of different sizes and shapes. Transmission electron microscopy (TEM), Raman spectroscopy

Excited state interactions of zeolite adsorbed porphyrins have been investigated by steady state luminescence quenching technique with certain antioxidants such as reduced glutathione, ascorbic acid and L-cysteine. The zeolite supported porphyrins, meso-tetra (N-methyl-4-pyridyl) porphyrin (H2TMPyP4+) and zinc tetra(N-methyl-4-pyridyl) porphyrin (ZnTMPyP4+) were prepared and characterized by various

A novel fluorescein-bridged perylene bisimide (PBI) dimer for liquid crystal (LC) with geometrically symmetric structure was developed. The mesomorphic results indicated that the energetically stable and unstable conformers of fluorescein fragments could lead to the transformation of mesophases from a hexagonal columnar mesophase to an uncertain phase at 136.9 °C in heating, whilst a stable hexagonal

This paper deals with the optical and photophysical properties of dihydrophenanthro[9,10-e][1,2,4]triazine fluorescent dyes doped in Silicate based sol–gel and homo-poly methyl methacrylate (PMMA). Solid hosts were found to effect on the optical and photophysical parameters such as molar absorptivity, cross sections of singlet–singlet electronic absorption and emission spectra, excited state lifetime

In this research, we designed a label-free fluorometric turn-on assay for trypsin and inhibitor screening, based on a spherical cationic gemini surfactant ethylene-bis (dodecyl dimethyl ammonium bromide) (EDAB)/heparin/Nile red (NR) supramolecular assembly system. The introduction of gemini surfactant EDAB as template greatly enhanced its salt resistance and resulted in the supramolecular assemblies

A benzothiazolium-based hemicyanine dye (probe 3) has been synthesized by attaching a morpholine group into a phenyl benzothiazolium skeleton. Probe 3 exhibited interesting photophysical characteristics including red emission (λem ≈600 nm), enhanced Stokes shift (Δλ ≈80 nm) and sensitivity to solvent polarity. Although the probe 3 exhibited almost no emission in aqueous environments (φfl ≈0.002), its

A novel fluorimetric and colorimetric chemosensor (1O) was synthesized with diarylethene-rhodamine unit and characterized by ESI–MS, 1H NMR, and 13C NMR. The chemosensor can selectively recognize extremely low concentrations of Hg2+ over a variety of metal ions with remarkable colorimetric and fluorescent responses. The colorimetric and fluorescent changes were ascribed the reaction between 1O and

Fluorescein (1), a known fluorescent tracer in microscopy with high photophysical properties, was esterified to have fluorescein ethyl ester (2) and O-ethyl-fluorescein ethyl ester (3) in excellent yields. All of them were investigated for the photophysical and electrochemical properties as potential organic semiconductor materials. Absorptions and emission spectra were taken in various solvents, compound

Intraoperative discrimination of thyroid and parathyroid tissues is fundamental in thyroid surgery. Recent fluorescence studies have shown stronger NIR emission in parathyroid tissue than in thyroid tissue, presenting a potential avenue for the development of a tool for surgical assistance. However, the fluorophore responsible for this emission has not yet been identified. In this work, spectroscopic

In the study, fluorescent imaging of live cells was performed using fluorescent carbon quantum dots derived from edible mushrooms species; Agaricus bisporus, Pleurotus ostreatus, and Suillus luteus as a fluorophore agent. Carbon quantum dots were synthesized through a facile and low-cost method based on microwave irradiation of dried mushroom samples in hydrogen peroxide solution under optimized conditions

Fluorescein molecules are extensively used to develop fluorescent probes for various analytes due to their excellent photophysical properties and the spirocyclic structure. The main structural modification of fluorescein occurs at the carboxyl group where different groups can be easily introduced to produce the spirolactam structure which is non-fluorescent. The spirolactam ring opening accounts for

A novel pH-responsive probe based on an imidazo[1,2-a]indole fluorophore architecture is reported. The probe was highly selective to strongly acidic pH (pKa = 3.56) with high sensitivity and a fast response time (within 30 s). The probe did not demonstrate any fluorescence changes in the presence of interfering metal ions, and it featured excellent reversibility under strongly acidic conditions. The

Bright photoluminescent neutral complexes having general formula [Ln(tbtz)3] (Ln = Eu, Tb; tbtz = tris(benzotriazol-1-yl)borate) were obtained by reacting K[tbtz] with EuCl3 and TbCl3. The emissions in the visible range, related to the f-f transitions of the trivalent lanthanide ions, are observable upon excitation with wavelengths shorter than 350 nm. The most intense emission bands correspond to

Two reactive phenanthrene derivatives, 4-(1H phenanthrol [9,10-d] imidazole-2-yl) benzaldehyde (PIB) and 6,9-dimethoxyphenanthro[9,10-c]furan-1,3-dione (PA) with high fluorescent quantum yields were prepared and used as fluorescent marker in fluorescence microscopy. In particular, silane modified μmZeolite-L containing amino group (-NH2) in the surface were labeled with the phenanthrene derivatives

This report describes a combined immunofluorescence and fluorescence viability stain applied as one staining solution for rapid detection of live Legionella pneumophila in mixed bacterial populations. Instead of sequential viability staining with the Invitrogen BacLight LIVE/DEAD staining kit followed by antibody-Alexa Fluor (AF) 647 conjugate staining to identify live L. pneumophila, a combined single

Cyanine-based probe-possessing indolium iodide and indole unit were synthesized in two-step with easy available raw material: a potential probe for the cyanide ion detection. The detecting ability of the probe was investigated and confirmed by a visual and instrumental approach. A noticeable color change from orange to colorless obtained only for cyanide ions and other added ions does not impart any

Two lanthanide-based MOFs (Ln-MOFs) were synthesized by reaction of Eu(III) or Tb(III) perchlorates with mixed dicarboxylates of 3,5-pdc and 1,2-bdc (3,5-H2pdc = 3,5-pyridinedicarboxylic acid; 1,2-H2bdc = 1,2-benzenedicarboxylic acid) by hydrothermal method. The chemical formulas of the two complexes were [Eu2(3,5-pdc)(1,2-bdc)2(H2O)4]n (1) and {[Tb2(3,5-pdc)(1,2-bdc)2(H2O)4]·2H2O}n (2). IR spectra

Dehydroergosterol (DHE, Δ5,7,9(11),22-ergostatetraen-3β-ol) is a naturally occurring fluorescent analog of cholesterol found in yeast. Since DHE has been shown to faithfully mimic cholesterol in a large number of biophysical, biochemical, and cell biological studies, it is widely used to explore cholesterol organization, dynamics and trafficking in model and biological membranes. In this work, we show

Biomacromolecules evolve and function inside the cell under crowded conditions. The effect of macromolecular crowding and confinement on nature and interactions of biomacromolecules cannot be ruled out. This study demonstrates the effect of volume exclusion due to macromolecular crowding on refolding rate of Gn-HCl induced unfolded hemoglobin. The in vivo like crowding milieu was created using dextran

Amino-acyl-quinoxalinone yellow dyes are cyclised analogues of the yellow azomethine dyes developed for, and still used in, silver halide colour photography. Unlike image azomethine dyes, which are rapidly deactivated in their excited states by torsion about the azomethine bond, amino-acyl-quinoxalinone dyes have an interesting photophysics because torsion is not possible due to their cyclised structure