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Synthesis of cyclobutane-fused oxazolidine-2-thione derivatives Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-15 Stefano Barranco, Federico Cuccu, Federico Devoto, Régis Guillot, Pierluigi Caboni, David J. Aitken, Angelo Frongia
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Thioxanthone-TfOH complex (9-HTXTF) photoredox enabled reduction of sulfoxides Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-15 Boan Chen, Jiayi Wang, Weiqiang Sun, Yuze Pan, Aishun Ding, Wangsheng Liu, Hao Guo
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Synthesis of 8-epi-l-swainsonine, related C6 alkylated derivatives and their α-l-rhamnosidase inhibition Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-14 Yuna Shimadate, Saki Oshima, Naoto Kasamatsu, Suzuka Yamamoto, Atsumi Taguchi, Robert J. Nash, George W.J. Fleet, Takuya Okada, Naoki Toyooka, Atsushi Kato
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Synthesis of spiro[piperidine-4,3′-pyrrolo[3,4-c]quinolines via 1,3-dipolar cycloaddition of azomethine ylides and 3-Nitro-2(1H)-quinolones Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-13 Márk Molnár, Tamás Gáti, Attila Bényei, Miklós Nyerges
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Practical synthesis of 1-alkyl 5-methyl ester 1,2,3-triazoles from low boiling point azides Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-13 Fen Wang, Shouliang Yang, Alberto Castanedo, John Braganza, Indrawan McAlpine
A simple and practical method for the synthesis of 1-alkyl-5-methyl ester1,2,3-triazoles from low boiling point azides is demonstrated. The triazoles were constructed by 1,3-dipolar cycloaddition of methyl 3-(trimethylsilyl) propiolate with alkyl azides containing one to four carbons. To better handle the volatility of the alkyl azides, a flow chemistry method was developed to ensure a safer reaction
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Oxidative [3 + 2] cycloaddition of triazenes and trisubstituted dichloroalkenes Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-08 Takuya Mitsuhashi, Daiya Kase, Ai Tomatsuri, Tsuyoshi Takada, Ryosuke Haraguchi
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Facile synthesis of a Lipid-compatible, Dual-functionalized, and enantiospecific photoactivatable linker Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-06 Dean T Marinucci, Fei Liu
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Total synthesis of (±)−paralemnolin A Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-06 Hideki Abe, Nanako Inaba, Mayu Nomura, Yuta Ogura, Naoki Fukazawa, Ryohei Saito–Moriya, Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito
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Supramolecular catalysis in phosphite hydrolysis to H-phosphonate by the resorcinarene hexameric capsule Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-05 Zina Osman, Laura Sperni, Fabrizio Fabris, Alessandro Scarso
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Zinc-aluminum mixed oxide nanocomposites catalyzed KA2 coupling of ketone, amine, and an alkyne: An environmentally benign approach Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-03 Rahul, Gunjan Purohit, Diwan S. Rawat
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Novel synthesis of 2,3-dihydrobenzofuran-3-amines from salicylic aldehydes: Trimethylsilyl as traceless activating group Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-02 Polina A. Khardina, Evgeny M. Buev, Vladimir S. Moshkin, Vyacheslav Y. Sosnovskikh
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Synthesis of the 3′-terminal dinucleotide of tRNA aminoacylated with the unnatural ω-thioaspartic acid Tetrahedron Lett. (IF 1.8) Pub Date : 2024-03-01 Yuta Shinotsuka, Akihisa Ikehara, Tae Hirai, Kaname Sasaki
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Synthesis of methyl-substituted aza[7]helicene with enhanced configurational stability and chiroptical performance Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-29 Xing-Yu Chen, Ji-Kun Li, Chan Wang, Xiao-Ye Wang
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Development of 1,3a,6a-triazapentalene derivatives as practical erasable fluorescent cell staining reagents Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-28 Yuna Kondo, Tenta Nakamura, Daisuke Tsuji, Ryota Sato, Sangita Karanjit, Reiko Akagi, Kosuke Namba
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Efficient access to spiro[quinazoline-thiophen](thi)ones via acetic acid mediated [3 + 2] annulation of quinazolin(thi)one enamines with dithianediol Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-27 Jingxi Fang, Zhentao Pan, Yingbo Rao, Yongmin Ma, Maozhong Miao
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Continuous flow synthesis of C-acyloxy-substituted aziridines in microchannel reactor: Addition of carboxylic acids to 2-methylenaziridines Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-27 Hao-Tian Sun, Bin Pan, Shan-Shan Zhang, Xian-Bin Su, Meng-Rui Xu, Zi-Qing Hu, Guang-Zhao Xu
A microchannel reactor-based continuous flow method for synthesizing diverse C-acyloxy-substituted aziridines has been developed, allowing for rapid and efficient synthesis within seconds.
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Molecular basis for the high enantioselectivity of the Ser47Leu variant of Candida antarctica lipase B toward (R)-But-3-yn-2-ol Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-24 Areum Park, Seul-Ah Kim, JiSeon Mun, Seongsoon Park
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Catalytic performance of Noyori–Ikariya-type ruthenium complex with tethered syn-ULTAM ligand for the asymmetric transfer hydrogenation of ketones Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-24 Simona Hašanová, Jernej Cingl, Tihomir Tomašič, Andrej Emanuel Cotman
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An attempted oxidative coupling approach to the scholarinine A framework Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-24 Kerry E. Jones, Fernando Martínez Lara, Blane P. Zavesky, Richmond Sarpong
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Ligand-Enabled Copper-Catalyzed N6-Arylation of 2′-deoxyadenosine and its analogues Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-23 Yuhua Ge, Weifan Yuan, Ruoqian Xie, Raghunath Bag, Yutong Zhou, Yujie Jiang, Madiha Butt, Gang Chen
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Effect of indoline substitution on ring opening in 6-nitro BIPS spiropyran derivatives Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-22 Kathryn A. Palasis, Andrew D. Abell
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Preparation of a water-soluble polymer having pheophorbide a side chains using glycopolymer assembly Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-22 Koji Matsuoka, Jyuichi Nakada, Masataka Nakazato, Takahiko Matsushita, Tetsuo Koyama, Ken Hatano
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A concise asymmetric total synthesis of 18-Ar-spirotryprostatin A analogs Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-21 Bin Jia, Zhao-Yang Sun, Si-Yue Ma, Ze-Qing Zhao, Cong Yan, Yuan Dong, Yang-Min Ma
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Immobilized eosin Y as heterogeneous photoredox catalyst in light-driven stereoselective aryl-enones cyclization Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-21 Simonetta Resta, Tommaso Benettin, Alessandra Puglisi, Laura Raimondi, Sergio Rossi
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The irreplaceable glycine: glycine homologs destabilize the collagen triple helix Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-20 David Kodr, Tomas Fiala, Helma Wennemers
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Sc(OTf)3-catalyzed alkyne-carbonyl metathesis-initiated cyclization for accessing naphtho[2,1-b]furan-1-ones under microwave heating Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-17 Wei-Le Li, Bao-Yang Liu, Chun-Mei Li, Xiang Wang, Wen-Juan Hao, Bo Jiang
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Facile synthesis of aryl and benzyl substituted 2-methylquinazolin-4(3H)-one ring by microfluidic flow reaction chemistry Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-16 Dongwook Wi, Jesus Campagna, Whitaker Cohn, Jessica Lee, Terran Cole, Barbara Jagodzinska, Varghese John
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Synthesis of carbacycloisodityrosine, an analogue of cycloisodityrosine in antitumor bicyclic hexapeptide RA-VII Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-15 Risa Hoshi, Yuya Shoda, Kaede Arita, Kou Shiraishi, Mika Sekine, Hirohisa Nagai, Naoki Wakiyama, Haruhiko Fukaya, Tsuyoshi Miura, Yukio Hitotsuyanagi
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Synthesis, structural characterization, and reactions of an adduct formed between mesoionic 1,3-diphenyltetrazolium-5-thiolate and diiodine Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-13 Yuta Matsukawa, Mirai Nakata, Tsunehisa Hirashita, Shuki Araki
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Dihydroacridine-functionalized pillar[5]arene with optical response towards alanine derivative Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-12 Zhiyong Peng, Yimin Cai, Jing-Lin Song, Wei Wang, Hai-Bo Yang
A new functionalized pillar[5]arene by combining pillar[5]arene host and dihydroacridine fluorophore has been successfully constructed, which revealed remarkable optical response towards alanine derivative.
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A formal Pd0-catalyzed 1,3-diaza-Claisen rearrangement Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-12 Yanbo Yang, José Madalengoitia
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Metal-free, late-stage nitration strategy to construct 6-(ortho-nitroaryl)amino purine derivatives enabled by t-BuONO Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-10 Yiwen Chen, Jianhui Liu, Xiguang Liu, Zhongkai Jiang, Shaorong Wang, Yixing Zhang, Mingwu Yu
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Dynamic emissive supramolecular polyrotaxanes with aggregation-induced emission property Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-07 Jie Zhu, Ponmani Jeyakkumar, Yutong Xie, Minzan Zuo, Haotian Xu, Kaiya Wang, Xiao-Yu Hu
Dynamic emissive supramolecular polyrotaxane with AIE-property.
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Palladium catalyzed C(sp3)–H bond activation of free carboxylic acids: An adventure of ligand evolution Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-07 Dong Li, Xiao-Bao He, Liang Jin, Xin Yu, Qi Zhang
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Highly effective one pot reaction from α-hydrazonoesters to give anilinoesters via α-diazoesters Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-07 Tomoki Kanuma, Eiko Yasui
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Dual role of DMSO in the intermolecular oxygenative bifunctionalization of ynamides Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-06 Kexin Gao, Shenyue Xie, Xialei Chen, Guoying Qian, Zhouting Rong
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Synthesis of novel spirocyclic 2-oxindole tethered to 2′-(3-(furan-2-yl)-1H-pyrazole-4-carbonyl)-hexahydropyrrolizine via 1,3-dipolar cycloaddition of the chalcone with azomethine ylide: Reaction of pyrazolyl-enaminone towards some heteroaromatic amines Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-05 Fatma M. Saleh, Hamdi M. Hassaneen, Ismail A. Abdelhamid, Mohamed A. Mohamed Teleb
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A simple and efficient sequential (3+2) annulation toward the construction of a novel contiguous dispiroheterocyclic scaffold Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-05 Zahra Karimi, Xingfu Wei, Jiamin Liu, Baomin Wang
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Synthesis of γ-Undecalactone via Organophotocatalyzed α-C-H Alkylation of 1-Octanol using Continuous-Flow Photoreactors Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-03 Meichen Xu, Xiao Yang, Yiming Li, Cunqian Miao, Juntao Ye
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A convenient one-pot synthesis of novel benzo[g]benzo[4,5]imidazo[2,1-b]quinazolines through Knoevenagel/Michael/Cyclization cascade reaction Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-29 Mohaddeseh Ahmadusefi-Sarhadi, Hossein Mehrabi, Farzaneh Alizadeh-Bami, Jared T. Shaw
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Chirality based on pillar[n]arenes and its complexes Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-02 Kai Diao, Chao Ruan, Ranran Wang, Shengke Li, Juli Jiang, Leyong Wang
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Redox-economical synthesis of α-substituted α-N-phthaloyl amino aldehydes using Fukuyama reduction Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-02 Riko Genka, Satoru Arimitsu
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Two new cytochalasins from Chaetomium sp. Strain Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-01 Miao Zhao, Xiao-Ya Xian, Lin Liang, Jin-Tao Gao, Li-Sheng Wang, Xian-Li Zhou, Cheng-Qin Liang
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Synthesis and biological characterisation of a des-aza-dasatinib tool compound Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-01 Julie Spicer, Jiney Jose, Woo-Jeong Lee, Samantha Rickard, Jack Flanagan
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A facile approach toward γ-branched amines via copper-catalyzed 1,3-aminoalkynylation and aminobromination of arylcyclopropanes Tetrahedron Lett. (IF 1.8) Pub Date : 2024-02-01 Yu Bu, Yingzi Zhang, Xiaoyan Shangguan, Shaoguang Sun, Yan Li, Qian Zhang
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Electrochemical bromination of electron-rich compounds employing LiBr as a “Br” source Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-29 Hui-juan Chen, Xiao-xue Jiang, Hong-ji Shi, Ming-ming Li, Kou Wang
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Synthesis of Dalargin, the synthetic Leu-enkephalin analogue in solid phase peptide synthesis Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-29 Vishnu Nomula, Prathama S. Mainkar, Kiranmai Nayani
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Dabco-catalysed selective chlorination of aromatics Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-27 Jun Xu, Xue Li, Qiji Li, Weiyi Tian, Xiaosheng Yang
A Lewis base catalyst DABCO for highly efficient electrophilic aromatic chlorination using NCS was presented. The mild conditions, easy-availability and stability of the catalyst and reagents, as well as good functional-group tolerance, showed the approach to be a versatile protocol for the late-stage aromatic chlorination of complex natural products and drugs.
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Oxidative construction of unusual indole-derived intermediates en route to conodusine A Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-23 Alexander J. Hughes, Steven D. Townsend
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Chemoselective synthesis of bridged benzo[no]tetraphen-8-one via copper-catalyzed radical dimerization of 1-alkynylnaphthols Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-26 Jian-Hua Chen, Jie Yang, Ke Xu, Xiao-Ling Wu, Jinfeng Zheng, Wei Huang, Bo Han, Gu Zhan
The chemoselective synthesis of bridged tetrahydro-benzo[]tetraphenones has been accomplished a copper-catalyzed radical dimerization of 1-alkynylnaphthols. This approach highlights the utilization of a cost-effective catalyst and an environmentally friendly oxidant under mild conditions.
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Novel antibacterial alkaloids from the Mariana Trench-derived actinomycete Streptomyces sp. SY2255 Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-26 Shuai Liu, Cangzhu Sun, Yura Ha, Mingzhu Ma, Nan Wang, Yufang Zhou, Zhizhen Zhang
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One pot synthesis of carboxylic acid, ester, and amide derivatives from iodoarenes in aqueous solubilized systems using sodium oleate as surfactant at room temperature Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-24 Ravi Pratap Singh, Sujan Shee, Meet Soni, Amol Kale, Lakshmi Shukla, Tanay Ghoshal, Vivek Mishra
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Selective monooxidation of symmetric dialdehydes in aqueous media Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-23 Pullaiah Kattanguru, Ren Ogawa, Yutaro Suzuki, Satomi Niwayama
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Divergent synthesis of cyclopentenyl- & 1,5-divinyl-ketones via gold-catalyzed oxidative coupling of 1,3-enynes with various olefins Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-17 Zhuang-Zhi Zhou, Yu-Jiang Wang, Qiang Zou, Zili Chen
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Recent advances on catalytic asymmetric hydrogenation of oximes and oxime ethers Tetrahedron Lett. (IF 1.8) Pub Date : 2024-01-17 Bin Lu, Jianchao Yu, Xumu Zhang, Gen-Qiang Chen