-
Multiple integrated computational approach to analyse wound healing potential of Symplocos racemosa bark as Matrix metalloproteinase inhibitors Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-18 Hafiz Abdul Rafey, Adnan Amin, Samir Anis Ross, Mohamed El-Shazly, Muhammad Ammar Zahid, Shah Iram Niaz, Fakhar Ul Mahmood, Hammad Ullah
The healing of wounds is the flagging concern in chronic wound cases especially when accompanied by pathogenic, diabetic comorbidities. Matrix metalloproteinases are associated with widespread path...
-
Could lactose-free foods influence the gut microbiome? Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-18 Eleonora Di Salvo, Nicola Cicero
Published in Natural Product Research: Formerly Natural Product Letters (Ahead of Print, 2024)
-
Effect of Gracilaria changii extract and its fraction in reverse cholesterol transport by targeting SR-BI gene Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-14 Mohd Rahaizuddin Rani, Ahmad Khusairi Azemi, Kamariah Bakar, Luqman Abu-Bakar, Tengku Sifzizul Tengku Muhammad, Noraznawati Ismail
This present study aimed to investigate the effects of Gracilaria changii (Red seaweed) extract and its fraction on scavenger receptor class B type I (SR-BI) gene expressions. In vitro studies of t...
-
Two novel ketone alkaloids from Portulaca oleraceaL. and their anti-inflammatory activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-12 Hongzhe Zhang, Jing Liu, Junjie Yao, Fan He, Xixiang Ying
Eleven compounds were obtained from Portulaca oleracea L., including two novel ketone alkaloids, (1, 2), 4-hydroxy-3-methoxybenzamide (3) (isolated for the first time), β-adenosine (4), oleracrylim...
-
Separation of crude methanol extract of Plantago major root: identification of phytochemicals and assessment of biological activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-12 Samaneh Rahamouz-Haghighi, Ali Sharafi
Plantago major root extracts were used for analysis by Gas Chromatography-Mass Spectrometry (GC-MS). The anticancer and antibacterial functions of extracts were also investigated. The dichlorometha...
-
Pharmacognostic standardization and evaluation of antiulcer potential of Olax psittacorum leaf extract Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-10 Pragyan Parimita Mansingh, Lopamudra Adhikari, Moonmun Dhara
The modern medicine has received many plants as a gift from ethnobotany. It is an efficient method of discovering new medicines. The leaves of Olax psittacorum (Lam.) Vahl. were extracted with etha...
-
Design, semi-synthesis of soft coral-derived Aspergillus sp. secondary metabolite geodin derivatives and their antibacterial activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-10 Gulab Said, Amjad Ali, Latif Ahmad
A series of novel ester derivatives 2 − 7, of natural product geodin 1, isolated from the soft coral-derived fungus Aspergillus sp., were designed and semi-synthesised through one step reaction wit...
-
Two new alkaloids from the roots of Cocculus hirsutus (L.) W. Theob Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-10 Shivani, Surekha Kumari, Prithvi Pal Singh, Prateek Singh Bora, Upendra Sharma
Two undescribed alkaloids, 15-carboxydihydroerysotrine (1) and (14 R)-4-methoxy-13,14-dihydrooxypalmatine (2), along with six known compounds, 1,6-didehydro-3,15,16-trimethoxy-9-methylerythrinanium...
-
Antioxidant constituents from Ribes glaciale Wall.: bioassay targeted in-vitro and in-silico evaluation Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-10 Rajendra Singh, Rohit Verma, Nitin Sati, Waseem Ahmad Ansari, Mohammad Faheem Khan
Bioassay targeted phyto-investigation of dried green walnut husk of Ribes glaciale Wall. yielded one new compound as β-D-glucopyrano (4′→3)-β-D-glucopyranose (1) and four known compounds namely sco...
-
Siamfuranones A–C, three novel furanone derivatives from the flowers of Uvaria siamensis and their biological activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Florian T. Schevenels, Supachai Jadsadajerm, Ratsami Lekphrom, Nuttapon Yodsin, Thanapat Suebrasri, Thanaset Senawong, Awat Wisetsai
Three previously undescribed furanone derivatives named siamfuranones A–C (1–3), together with 11 known compounds (4–14), were isolated from the flowers of Uvaria siamensis. Their planar structures...
-
Synthesis, modification and biological activity of 2,3-indoles of Glycyrrhetinic acid Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-07 Lidia Baltina, Elza Karimova, Timur Nugumanov, Svetlana Petrova, Svetlana Gabdrakhmanova, Regina Khisamutdinova
The synthesis of 2,3-indoles of Glycyrrhetinic acid (GLA) and its methyl ester was carried out by the Fischer reaction. Reductive transformations of GLA methyl ester 2,3-indole 3a were carried out ...
-
Tamarind genus chemical composition and biological activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-07 Nahla S. El-Gazzar
Tamarindus indica L., the sole species in the genus Tamarind, which is a member of the subfamily Caesalpiniaceae in the family Leguminosae (Fabaceae), is extensively dispersed in many tropical and ...
-
Phytochemical profiling of Striga asiatica; characterisation and anti-microbial assessment of the isolates Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-06 Ahmed Elbermawi, Fazila Zulfiqar, Pankaj Pandey, Amar G. Chittiboyina, Ikhlas A. Khan, Zulfiqar Ali
One undescribed compound, striasinol (1), and twelve previously described compounds were isolated from the aerial parts of Striga asiatica. Structure elucidation of isolated compounds was achieved ...
-
Evaluation of chalcones as new glycogen phosphorylase inhibitors – an in-vitro and in-silico approach Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Talal Ahmed Awad, Fatima Alfatih, Muhammad Shafiq, Mohnad Abdalla, Samia T. Al-Shouli, Amani Bashir, Maaweya E. Awadalla, Hassan A. Alhazmi, Mohammed Albratty, Hafiz A. Makeen, Asaad Khalid, Zaheer Ul-Haq
Diabetes mellitus (DM) remains one of the pivotal diseases that have drawn the attention of researchers recently and during the last few decades. Due to its devastating symptoms, attempts to develo...
-
Phytochemical composition of the diethyl ether extract of Artemisia lactiflora Wall. ex DC and its antimetastatic activity in human lung cancer cells Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Nateelak Kooltheat, Kunwadee Noonong, Karl M. Hanson, Udom Lao-On
Artemisia lactiflora Wall. ex DC. is a traditional Chinese medicinal plant used in the treatment of menstrual and hepatic disorders due to its antioxidant and anti-inflammatory properties. However,...
-
Determination of the volatile chemical profile of Momordica charantia (bitter melon) leaf and fruit by GC-MS Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Natália Ferreira Almeida, Edenilson dos Santos Niculau, Pedro Cordeiro Toledo Lima, Wanderson Ferreira da Silva
The plant Momordica charantia (Cucurbitaceae), popularly known as bitter melon, snake fruit, Saint Vincent’s herb, or little melon, is an African species that has developed in tropical and subtropi...
-
Molecular modelling approaches can reveal the Molecular interactions established between antimalarial targets of hemozoin pathway and the organic phytochemicals of Artocarpus species Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Surabhi Chaurasia, Anima Pandey
Ayurveda, the traditional Indian medical system, has potential applications in early malaria treatment. In an in silico docking study, 50 phytochemicals from two plants Artocarpus lakoocha Roxb. (A...
-
The investigation of hawthorn (Crataegus orientalis) plant’s inhibition effect on angiotensin converting enzyme and in silico studies Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Mahmut Yavuz, Fatih Çağlar Çelikezen, Mehmet Firat, Zehra Baş, Vedat Türkoğlu
Hawthorn plant is used among people due to its cardiovascular, anti-inflammatory, and antihistamine properties. But no scientific study has been done about Crataegus orientalis (Mill.) M.Bieb. The ...
-
Phytochemical profiles and evaluation of the biological potential of ethyl acetate and n-butanol fractions of the aerial parts of Cistus albidus L Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-05 Ouissem Gherboudj, Naima Boutaghane, Zahia Kabouche, Lamia Djeblia, Leila Zerrougui, Manel Bekrar
The phytochemical profiles of the ethyl acetate (EAFCA) and n-butanol (BFCA) fractions of the aerial parts of Cistus albidus L., were characterised by a developed LC-ESI-MS/MS method, using 53 fing...
-
Chemical constituents of Penicillium ferraniaense GE-7 and their cytotoxicities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-04 Yan Wang, Shao-Hua Song, Lei-Ming Wu, Xue Zhou, Qing-Ren Lu, Ai-Ping Yin, Sheng Yin, Gui-Hua Tang
Phytochemical investigation on the plant endophytic fungus Penicillium ferraniaense GE-7 led to the isolation of 18 compounds including one new α-pyrone derivative, peniferranige A (1). The structu...
-
Synthesis of xylan and lignin based hydrogels and their use as growth media for rice (Oryza sativa) Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-03 Japanpreet Kaur, Isha Dudeja, Gagandeep Kaur Chahal, Ramandeep Kaur Mankoo, Ramandeep Kaur
Different hydrogels were synthesised using lignin and xylan (extracted from rice straw) as the raw material, PVA as matrix template, citric acid, and succinic acid as crosslinkers and were structur...
-
Two new glycosides from the root bark of Paeonia ostii Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-03 Chuihao Kong, Kaidi Wang, Lei Sun, Shihui Qin, Renzhong Wang, Fengqing Xu
Two new glycosides, ethyl-O-β-D-furanosyl-(1→6)-O-β-D-glucopyranoside (1) and (5-′′)-galloyl-ethyl-O-β-D-furanosyl-(1→6)-O-β-D-glucopyranoside (2), together with eight known compounds (3–10) were o...
-
Withaperuvin O, a new withanolide from Physalis peruviana L Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-01 Pham Van Cong, Vu Thi Trang, Le Quynh Lien, Vu Xuan Hoan, Tran Minh Ngoc, Do Thanh Tuan, Do Thi Thu Hien, Ngo Van Hieu, Ngo Viet Duc, Hoang Le Tuan Anh
Physalis peruviana L. (Solanaceae) has been used in tropical and subtropical countries of the world as medicinal and fruit trees. In this study, a new withanolide named withaperuvin O (1) and seven...
-
Effects of trigonelline, diosgenin, and Cistanche deserticola polysaccharide on the culture of female germline stem cells in vitro Nat. Prod. Res. (IF 2.2) Pub Date : 2024-03-01 Xiaoli Yu, Yikai Qiu, Jinhua Li, Yanping Zhang, Qian Wang, Zehua Jin, Xinrui Liu, Xiuying Pei
Female germline stem cells (FGSCs) are renewable sources of oocytes that play an indispensable role in re-establishing mammal fertility. Here, we have established FGSCs from neonatal mice, which ex...
-
Identification and α-glucosidase inhibitory activity evaluation of two new coumarins derived from Mansonia gagei J. R. Drumm. Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-29 Huong Thi Thu Le, Yusuke Hioki, Duy Vu Nguyen, Thi-Kim-Dung Le, Van-Kieu Nguyen, Tien T. Dang, Thi-Anh-Tuyet Nguyen, Thi-Hoai-Thu Nguyen, Thi-Hai-Duyen Vu, Thi-Kim-Ngan Pham, Masaki Kita, Warinthorn Chavasiri
Five coumarins were isolated from the heartwood of Mansonia gagei, which included two newly discovered compounds, namely 11-hydroxypopulene E (1) and mansorin D (2), along with three previously ide...
-
New dammarane-type triterpenoids from the whole plant of Euphorbia hypericifolia Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-28 Mengke Xu, Jiacheng Liu, Wenrui Sun, Yutian Chen, Mengyu Wang, Yangfan Zhou
Euphorhypenoids A (1) and B (2), two new dammarane-type triterpenoids, along with four known tetracyclic triterpenoids (3−6), were isolated from the whole plant of Euphorbia hypericifolia. The stru...
-
Characterisation of bioactive compounds from leaves of Smilax fluminensis Steud. by gc-MS and LC-DAD-MS, and analysis of its antioxidant and ecotoxicological activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-29 Lucas Santos Azevedo, Juliana Costa Fonseca, Ana Hortência Fonsêca Castro, Katyuce de Souza Farias, Vanessa Samúdio Santos Zanuncio, Denise Brentan Silva, Luciana Alves Rodrigues dos Santos Lima
Smilax fluminensis Steud. is distributed in Central and South America, commonly named as ‘salsaparilha’ or ‘japicanga’. In the present work, the chemical composition was determined, antioxidant and...
-
Production, physico-chemical properties and antioxidant activity of melanin from Annulohypoxylon stygium (Lév.) Y.M. Ju, J.D. Rogers and H.M. Hsieh Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-29 Ruofan Liu, Cuiyuan Mo, Xianfu Meng, Xuetuan Wei, Aimin Ma
To obtain higher melanin production in liquid culture, culture conditions of Annulohypoxylon stygium (Lév.) Y.M. Ju, J.D. Rogers and H.M. Hsieh were optimised. The results showed that using single ...
-
If speed is of the essence: rapid analysis of ambergris by APCI compact mass spectrometry Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-28 Steven J. Rowland, Michael J. Wilde, Paul A. Sutton, Sabena J. Blackbird, George A. Wolff
The use of atmospheric pressure chemical ionisation (APCI) compact mass spectrometry (CMS) was investigated for the analysis of jetsam and museum-archived ambergris and of ambergris components in p...
-
Phytochemical study of ‘taiji’ (Handroanthus impetiginosus (Mart.) Mattos) and ‘ka’a ovetĩ’(Luehea divaricata Mart.) extracts Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-27 Eva Sánchez-Hernández, Claudia Cáceres-González, José Ignacio García-Valdecasas, Sintya Valdez-Ayala, Jesús Martín-Gil, Pablo Martín-Ramos
This study explores the phytochemical composition of leaf extracts from Handroanthus impetiginosus (Mart.) Mattos and Luehea divaricata Mart., used in a contraceptive decoction by Mbya-Guarani wome...
-
Cytotoxic constituents from the fruit of Solanum aculeastrum Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-26 Nadine-Phalone Tinguep Tchapnda, Ruth Bibiane Njinkou Njambouo, Marguerite Hortence Tchuendem Kenmogne, Pascal Djimeli Douanla, Yoshihito Shiono, Turibio Kuiate Tabopda
A new triterpene, aculeastrumone A (1), a new triterpene saponin aculeastrumoside A (2), and eleven known compounds (3–13) were isolated from MeOH/Water (80/20) extract of the fruits of Solanum acu...
-
A comparative study of secondary metabolites profiling and biological activity of Smyrnium olusatrum L. leaf, flower and fruit Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-28 Dhouha Hamdi, Aziz Hafidi, Jean Jacques Lemaire, Chokri Messaoud
Essential oil (EO) composition of Smyrnium olusatrum was characterised by high proportion of furanosesquiterpenes (51.66–69.35%). The leaf methanolic extract composition was found to be rich with Q...
-
Evaluation of traditional uses, phytochemical constituents, therapeutic uses and future prospects of Pyracantha genus: a systematic review Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-27 Aishna Chauhan, Ritesh Banerjee
The Pyracantha genus consists of evergreen shrubs distributed from Southeast Europe to South-East Asia. They are found in geographical regions of India, China, and South West Europe. They are used ...
-
Chemical composition and toxicity of Moroccan mentha spicata and Artemisia absinthium essential oils against Pthorimaea operculella, the potato moth Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-25 Fatima Mahboub, Mohamed Dakir, Khawla Aloui, Rafii Soumaya, Keltoum El Bouhmadi
The current methods employed to mitigate losses caused by Phthorimaea operculella primarily rely on the application of synthetic insecticides. We have utilised essential oils of Mentha spicata L. a...
-
Investigation of the molecular mechanism of Danggui Buxue tang in treating lung cancer using network pharmacology and molecular docking techniques Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-25 Dantong Zhu, Shun Li, Long Xu, Xijing Ren, Shudong Wang, Jianjun Chen, Ershu Zhao, Zhendong Zheng
This study used network pharmacology and molecular docking techniques to investigate the molecular targets and pathways of Danggui Buxue Tang (DBT) in treating lung cancer. The compound-target netw...
-
Identification and nitric oxide production inhibitory activity of phenolic derivatives from the trunks of Gnetum latifolium Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-23 Nguyen Thi Thu Hoa, Ba Thi Cham, Nguyen Thi Hoang Anh, Nguyen Tuan Hiep, Nguyen Thi Kim Anh, Le Thi Hong Nhung, Sabrina Adorisio, Domenico V. Delfino, Trinh Thi Thuy, Nguyen Thi Thuy Linh
Phytochemical investigation of the trunks from Gnetum latifolium led to the isolation of a novel phenolic glucoside, 2E-2,4-di-(3,4-dihydroxyphenyl)but-2-en-1-yl-O-β-D-glucopyranoside (1), along wi...
-
Genus Helleborus: a comprehensive review of phytochemistry, pharmacology and clinical applications Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-19 Shixing Li, Xiaolin Chen, Jiamei Tang, Dongdong Zhang, Yi Jiang, Huawei Zhang, Xiaomei Song, Wei Wang, Yuze Li
The genus Helleborus belongs to the Ranunculaceae family, distributed in southeastern Europe and western Asia. In folk medicine, it is commonly used as an anti-inflammatory and analgesic medicine f...
-
Pharmacological properties of Hoya (Apocynaceae): a systematic review Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-23 Muhammad Khairil Rumaling, Siat Yee Fong, Pasupuleti Visweswara Rao, Johnny Gisil, Mohd Hijaz Mohd Sani, Wan Salman Wan Saudi
In tropical forests, Hoya, a plant with significant indigenous medicinal applications, has been underexplored in pharmacological studies. This systematic review meticulously investigates the divers...
-
Identifying potential Q-markers for quality evaluation of Zhenyuan capsule by integrating chemical analysis, network pharmacology, molecular docking, and molecular dynamics simulations Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-22 Zixuan Zhao, Qinwen Yang, Yinghong Ma, Baoping Jiang, Ke Ning, Guangli Sun, Zhonghao Sun, Zhaocui Sun, Guoxu Ma, Xiaole Tong, Hailong Qin, Hong Liu, Xudong Xu, Meihua Yang, Haifeng Wu, Xin Liu
Quality markers (Q-markers) are of great significance for quality evaluation of herbal medicines. Zhenyuan Capsule (ZYC) is a kind of Chinese patent medicine used to treat cardiovascular diseases. ...
-
Isolation and identification of Methylobacterium komagatae and its application in textile industries Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-22 Hridoyjit Phukon, Kumar Harshvardhan, Neelav Sarma, Pankaj Kumar, Mohan Lal, Dipul Kalita
A light pink-coloured, rod-shaped, gram-negative bacterium isolated from an unproductive crude oil production area was considered as a sample for this study. The 16S rRNA gene sequence identified t...
-
Association effect of the phytocannabinoid beta-caryophyllene and indomethacin carried in topical nanoemulgels: an evaluation by in vivo anti-inflammatory model Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-21 Patrícia Weimer, Graziela de Araújo Lock, Ketly Amaral Antunes Nunes, Rochele Cassanta Rossi, Letícia Scherer Koester
The sesquiterpene β-caryophyllene, classified as a phytocannabinoid compound, has been widely studied owing to its multi-target action. In addition, this compound has demonstrated application as a ...
-
Biotin as a structural component in the detection of small model antigens in BLA-S-ELISA Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-20 Mladen Simonović, Sanja Ostojić, Darko Micić, Petar Djurdjić, Thorsten Mix, Čeda Kuzmanović, Drago Jelovac
An interesting biotin-linked-antigen-Sandwich-ELISA was developed (BLA-S-ELISA), which based on the captured Trinitrophenol-Biotin (TNP-Biotin) molecule between the immobilised monovalent antibody ...
-
On the traditional medicinal plants and plant-derived natural drugs used by indigenous people of Nagaland, India Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-19 Soching Luikham, Jhimli Bhattacharyya
An ethnobotanical documentation on the medicinal plants used by local people of Nagaland (North-east India) has been presented here. The study explored 33 plant species (with their local names, ind...
-
Phytochemical investigation of Nigrospora zimmermanii isolated from Poincianella pluviosa (Sibipiruna): metabolites characterisation and screening for anti-inflammatory activity Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-21 Miller Santos Ferreira, Albert Katchborian-Neto, Karen de Jesus Nicácio, Mario F. C. Santos, Danielle F. Dias, Daniela A. Chagas-Paula, Marisi G. Soares
Endophytic fungi residing symbiotically in plant tissues are promising sources of bioactive natural products. This study explored the anti-inflammatory potential of an endophytic fungus isolated fr...
-
Biological capacities of seven Chilean ferns Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-20 Patricia Velásquez, Josefina Trucco, Eduardo Muñoz-Carvajal, Daniela Bustos, Rafael Viteri, Gloria Montenegro, Ady Giordano
Sticherus squamulosus, Hymenophyllum dentatum, Blechnum microphyllum, Polypodium Feuillei, Blechnum chilense, Lophosoria quadripinnata, and Lissopimpla excelsa are native fern species found in sout...
-
Biotransformation of curcumin by Streptomyces sp. K1-18 isolated from mangrove soil Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-19 Nurul Iman Aminudin, Wan Muhammad Shafiq Wan Jaafar, Nurul Mehiran Shafikah Mohd Amin, Raudah Kamarul Baharin, Zaima Azira Zainal Abidin
Biotransformation is recognised as a green chemistry tool to synthesise diverse natural product analogues for valorisation of their chemistry and bioactivities. It offers significant benefits compa...
-
A new isopimarane-type diterpene with anti-inflammatory activity from the Clinacanthus nutans Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-19 Hai-Xia Liao, Can-Can Shi, Rui-Juan Wang, Tai-Ming Shao, Ming-Xiong Tan
A new isopimarane-type diterpene clinacanoid A (1) together with seven known terpenoids (2–8) were obtained from the Clinacanthus nutans. Their structures were elucidated based on extensive spectro...
-
Evaluation of iso-quinoline alkaloids by RP-HPLC-PDA in different Berberis species collected from Western Himalayan Region Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-14 Mridul Kant Chaudhary, Bhanu Kumar, Priyanka Agnihotri, Sharad Srivastava
The genus Berberis has high significance in Indian and other traditional systems of medicine due to the presence of iso-quinoline alkaloids. This study was conducted to record the metabolic variati...
-
Molecular docking targeting autophagy pathway mediate abrogation of NASH by specific functional foods: update review Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-16 Merehan Alaa-ElDin. Mohamed, Shaimaa Rihan, Mustafa M.M. Elbakry, Said S. Moselhy
Autophagy is a very well-conserved self-digestive mechanism that transports unwanted or disposable cytoplasmic debris to lysosomes for destruction, including misfolded proteins and damaged organell...
-
Chemical constituents from the roots of Zygostelma benthamii (Apocynaceae) and their anti-proliferative activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-12 Tanakiat Chompupong, Florian T. Schevenels, Thanaset Senawong, Ratsami Lekphrom
Phytochemical investigation of the roots of Zygostelma benthamii Baill. (Apocynaceae) led to the isolation of eleven known compounds. The isolated compounds were identified by analysis of physical ...
-
Synthesis and evaluation of nitrogen-containing derivatives of 3,11-dioxo-olean-12-en-30-oic acid against HIV-1 protease Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-11 Liangliang Zheng, Bowen Pan, Tingting Tang, Huilin Xu, Weili Hu, Youqing Zhang, Xin Wei, Xia Liu, Qing Wu, Yang Shi, Jian Yang, Ying Zhou, Ying Wei
Thirteen nitrogen-containing derivatives of 3,11-dioxo-olean-12-en-30-oic acid were synthesised by introducing various amino acids and nitrogen-containing heterocyclic groups at the 30-carboxyl gro...
-
Conamonin A and dihydrochalcones from the whole plants of Conamomum rubidum (Lamxay & N.S.Lý) Škorničk. & A.D. Poulsen showing anti-inflammatory and cytotoxic activities Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-14 Hanh Nhu Thi Hoang, Hung Quoc Vo, Linh Thuy Khanh Nguyen, Linh Thuy Thi Tran, Hoai Thi Nguyen, Ty Viet Pham, Hieu Trung Le, Cuong Viet Canh Le, Bao Chi Nguyen, Duc Viet Ho
A new compound, conamonin A (1), was isolated from the whole plants of Conamomum rubidum with eight known dihydrochalcones (2-9). Their structures were elucidated by a combination of spectroscopic ...
-
Pentacyclic triterpenes from the leaves of Camellia hakodae Ninh Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-14 Thanh Tuyen Nguyen, Duc Tuan Cao, Hong Ngoc Tran, Thi Hanh Nguyen, Gia Dien Pham, Van Hieu Tran, Quang Duong Pham, Thi Thu Thuy Tran, Minh Tin Vu, Dinh Hoang Vu
Nine pentacyclic triterpene derivatives including new 3-O-cis-p-coumaroyl trichadenic acid B (1) and two new ursane-type triterpene derivatives, 11α,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)etha...
-
Potent bioactive metabolites from Olea ferruginea Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-14 Nisar Ahmad, Yan Wang, M. Iqbal Choudhary, Sheema, Rasool Khan, Salman Zafar
Seven known (1-7) and one new compound (8) were isolated and identified from the stem of Olea ferruginea. The species has been recognised as a new source for six of the known metabolites (1, 3, 4, ...
-
An unusual 2-O-glyceryl-glycosyl-γ-pyrone from Erigeron annuus (L.) with potential antifungal activity: in-vitro and in-silico study Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-14 Mohamed H. Abd El-Razek, Ahmed H. El-Desoky, Abdelhalim A. Elgahamy, Shaymaa M. Bata, Tarik A. Mohamed, Mohamed-Elamir F. Hegazy
Phytochemical characterisation of the polar fraction of Erigeron annuus extract led to the isolation of glycerylerigeroside (1), a unique γ-pyrone derivative. Structure of 1 was decided by intensiv...
-
Guettarda uruguensis (Rubiaceae): antioxidant and anti-inflammatory plant with quercetin and esters of p-coumaric acid Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-12 Ana Flavia Schvabe Duarte, Daniela Maria Soares, Luciane Dalarmi, Mariana Saragiotto Krause, Fernanda Maria Marins Ocampos, Railson Henneber, Marilis Dallarmi Miguel, Deise Prehs Montrucchio, Obdulio Gomes Miguel
Guettarda (Rubiaceae) is a genus known for its diverse range of bioactive compounds, with demonstrated anti-inflammatory and antioxidant properties. Guettarda uruguensis Cham. & Schltdl., commonly ...
-
Larvicidal activity of diterpenes from Xylopia langsdorfiana St. Hilaire & Tulasne (Annonaceae) against Aedes aegypti linn. (diptera: culicidae) Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-11 Karlos Antonio Lisboa Ribeiro-Júnior, Sâmia Andrícia Souza da Silva, João Xavier de Araújo-Júnior, João Gomes da Costa, Henrique Fonseca Goulart, Vanderson Barbosa Bernardo, Marcelo Sobral da Silva, Josean Fechine Tavares, Antonio Euzébio Goulart Santana
Mosquitoes of the Aedes genus are responsible for transmitting many vector-borne viral diseases worldwide. Hundreds of thousands of people die annually from vector-borne diseases, including West Ni...
-
Fucoidan a sulphated polysaccharide of brown seaweeds: a potential anticancer agent to treat oral cancer Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-10 Sivagnanavelmurugan Madasamy, Dhanraj Ganapathy, Maheshwaran Easwaran, Venkidasamy Baskar
Published in Natural Product Research: Formerly Natural Product Letters (Ahead of Print, 2024)
-
Protective effects of madecassoside, a triterpenoid from Centella asiatica, against oxidative stress in INS-1E cells Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-10 Swee Ching Tan, Ramkumar Rajendran, Subrat Kumar Bhattamisra, Purushotham Krishnappa, Fabian Davamani, Ebenezer Chitra, Stephen Ambu, Brian Furman, Mayuren Candasamy
Progressive decline in β cell function and reduction in the β cell mass is important in type 2 diabetes. Here, we tested the hypothesis that madecassoside’s previously demonstrated in vivo protecti...
-
Chemical constituents from Microstachys chamaelea (Euphorbiaceae) with cytotoxic and antioxidant properties Nat. Prod. Res. (IF 2.2) Pub Date : 2024-02-12 Watchara Sangsopha, Florian T. Schevenels, Ratsami Lekphrom, Somsak Ruchirawat
Phytochemical investigation of Microstachys chamaelea led to the isolation and identification of fourteen known compounds after analysis of spectroscopic data. They consist of eight flavonoids (1–8...