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Geometric Antibody Engineering Reveals the Spatial Factor on the Efficacy of Bispecific T Cell Engagers ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-16 Yu Zhang, Zhe Yang, Dilizhatai Saimi, Xiaowen Shen, Junqing Ye, Bingke Yu, Noah Pefaur, Justin M. Scheer, Andrew E. Nixon, Zhixing Chen
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Introducing Our Authors ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-15 Katie Nieves
This article has not yet been cited by other publications.
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Click-Capable Phenanthriplatin Derivatives as Tools to Study Pt(II)-Induced Nucleolar Stress ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-14 Paul D. O’Dowd, Andres S. Guerrero, Katelyn R. Alley, Hannah C. Pigg, Fiona O’Neill, Justine Meiller, Chloe Hobbs, Daniel A. Rodrigues, Brendan Twamley, Finbarr O’Sullivan, Victoria J. DeRose, Darren M. Griffith
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Roles of Nucleic Acids in Protein Folding, Aggregation, and Disease ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-13 Theodore J. Litberg, Scott Horowitz
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A Humanized Mouse Model Coupled with Computational Analysis Identifies Potent Glycolipid Agonist of Invariant NKT Cells ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-13 Noemi A. Saavedra-Avila, Natalia B. Pigni, Donald R. Caldwell, Florencia Chena-Becerra, Jose Intano, Jr, Tony W. Ng, Divya Chennamadhavuni, Steven A. Porcelli, José A. Gascón, Amy R. Howell
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Substrate Promiscuity of the Triceptide Maturase XncB Leads to Incorporation of Various Amino Acids and Detection of Oxygenated Products ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-07 Chin-Soon Phan, Litao Chang, Thi Quynh Ngoc Nguyen, Angelica Faith L. Suarez, Xuen Huei Ho, Huiyi Chen, Ivan Yu Fan Koh, Brandon I. Morinaka
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Correction to “A cAMP Sensor Based on Ligand-Dependent Protein Stabilization” ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-08 Mariapaola Sidoli, Ling-chun Chen, Alexander J. Lu, Thomas J. Wandless, William S. Talbot
The original publication correctly reported the lesion in gpr161a and the corresponding genotyping primers, but the sgRNA target sequence was shown incorrectly in Table S1. The authors regret this error. The gpr161a sgRNA target sequence has been corrected in Table S1 in the Supporting Information with this Correction. The Supporting Information is available free of charge at https://pubs.acs.org/doi/10
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Advancing Kir4.2 Channel Ligand Identification through Collision-Induced Affinity Selection Mass Spectrometry ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-07 Yushu Gu, Miaomiao Liu, Linlin Ma, Ronald J. Quinn
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Uncovering the Association Mechanism between Two Intrinsically Flexible Proteins ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-05 Angy Liseth Dávalos, José David Rivera Echeverri, Denize C. Favaro, Ronaldo Junio de Oliveira, Gustavo Penteado Battesini Carretero, Caroline Lacerda, Iolanda Midea Cuccovia, Marcus Vinicius Cangussu Cardoso, Chuck S. Farah, Roberto Kopke Salinas
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Bioorthogonal Metabolic Labeling of the Virulence Factor Phenolic Glycolipid in Mycobacteria ACS Chem. Biol. (IF 4.0) Pub Date : 2024-03-05 Lindsay E. Guzmán, C. J. Cambier, Tan-Yun Cheng, Kubra F. Naqvi, Michael U. Shiloh, D. Branch Moody, Carolyn R. Bertozzi
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An Upstream G-Quadruplex DNA Structure Can Stimulate Gene Transcription ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-28 Yuqi Chen, Angela Simeone, Larry Melidis, Sergio Martinez Cuesta, David Tannahill, Shankar Balasubramanian
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Functional and Promiscuity Studies of Three-Residue Cyclophane Forming Enzymes Show Nonnative C–C Cross-Linked Products and Leader-Dependent Cyclization ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-28 Angelica Faith L. Suarez, Thi Quynh Ngoc Nguyen, Litao Chang, Yi Wei Tooh, Rubin How Sheng Yong, Li Chuan Leow, Ivan Yu Fan Koh, Huiyi Chen, Jeffery Wei Heng Koh, Arunachalam Selvanayagam, Vernon Lim, Yi En Tan, Irene Agatha, Fernaldo R. Winnerdy, Brandon I. Morinaka
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Shine–Dalgarno Accessibility Governs Ribosome Binding to the Adenine Riboswitch ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-27 Julius Blechar, Vanessa de Jesus, Boris Fürtig, Martin Hengesbach, Harald Schwalbe
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Exponential Combination of a and e/g Intracellular Peptide Libraries Identifies a Selective ATF3 Inhibitor ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-27 Miao Yu, T.M. Simon Tang, Lila Ghamsari, Graham Yuen, Claudio Scuoppo, Jim A. Rotolo, Barry J. Kappel, Jody M. Mason
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Synthesis and Enzymatic Incorporation of a Dual-App Nucleotide Probe That Reports Antibiotics-Induced Conformational Change in the Bacterial Ribosomal Decoding Site RNA ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-26 Saddam Y. Khatik, Sarupa Roy, Seergazhi G. Srivatsan
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Glyco-Engineering Cell Surfaces by Exo-Enzymatic Installation of GlcNAz and LacNAz Motifs ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-23 Fabiola V. De León González, Marie E. Boddington, Joshua M. Kofsky, Martha I. Prindl, Chantelle J. Capicciotti
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Controlling Substrate- and Stereospecificity of Condensation Domains in Nonribosomal Peptide Synthetases ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-23 Huiyun Peng, Julian Schmiederer, Xiuqiang Chen, Gianni Panagiotou, Hajo Kries
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Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-22 YongLe He, Jinnette Tolentino Collado, James N. Iuliano, Helena A. Woroniecka, Christopher R. Hall, Agnieszka A. Gil, Sergey P. Laptenok, Gregory M. Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B. French, Andras Lukacs, Stephen R. Meech, Peter J. Tonge
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Structure and Substrate Specificity of S-Methyl Thiourocanate Hydratase ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-22 Camille M. Vasseur, Dishani Karunasegaram, Florian P. Seebeck
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De Novo Screening and Mirror Image Isomerization of Linear Peptides Targeting α7 Nicotinic Acetylcholine Receptor ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-21 Xiuxiu Cao, Tianqi Liu, Tao Wang, Xudong Wang, Ziyan Xu, Li Zhou, Changlin Tian, Demeng Sun
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Antibacterial Marinopyrroles and Pseudilins Act as Protonophores ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-20 Gabriel Castro-Falcón, Jan Straetener, Jan Bornikoel, Daniela Reimer, Trevor N. Purdy, Anne Berscheid, Florence M. Schempp, Dennis Y. Liu, Roger G. Linington, Heike Brötz-Oesterhelt, Chambers C. Hughes
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Introducing Our Authors ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-16 Katie Nieves
This article has not yet been cited by other publications.
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Analysis of the Valgamicin Biosynthetic Pathway Reveals a General Mechanism for Cyclopropanol Formation across Diverse Natural Product Scaffolds ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-15 Rory F. Little, Felix Trottmann, Hideki Hashizume, Miriam Preissler, Sandra Unger, Ryuichi Sawa, Hajo Kries, Sacha Pidot, Masayuki Igarashi, Christian Hertweck
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Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2 ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-10 Matiss Maleckis, Mario Wibowo, Tetiana Gren, Scott A. Jarmusch, Eva B. Sterndorff, Thomas Booth, Nathalie N. S. E. Henriksen, Christopher M. Whitford, Xinglin Jiang, Tue S. Jørgensen, Ling Ding, Tilmann Weber
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On the Question of CO’s Ability to Induce HO-1 Expression in Cell Culture: A Comparative Study Using Different CO Sources ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-10 Xiaoxiao Yang, Qiyue Mao, Binghe Wang
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Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-08 Thuan-Ethan Ngo, Andrew Ecker, Byeol Ryu, Aurora Guild, Ariana Remmel, Paul D. Boudreau, Kelsey L. Alexander, C. Benjamin Naman, Evgenia Glukhov, Nicole E. Avalon, Vikram V. Shende, Lamar Thomas, Samira Dahesh, Victor Nizet, Lena Gerwick, William H. Gerwick
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Targeted Extracellular Protein Degradation by Dendronized DNA Chimeras ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-08 Chenghong Zhu, Weishan Wang, Yan Wang, Weijie Zhang, Yan Zhang, Jinbo Li
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N-Terminal Proline Editing for the Synthesis of Peptides with Mercaptoproline and Selenoproline: Mechanistic Insights Lead to Greater Efficiency in Proline Native Chemical Ligation ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-07 Brice A. Ludwig, Christina R. Forbes, Neal J. Zondlo
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Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-07 Unai Atxabal, Corwin Nycholat, Johannes M. Pröpster, Andrea Fernández, Iker Oyenarte, Maria Pia Lenza, Antonio Franconetti, Cátia O. Soares, Helena Coelho, Filipa Marcelo, Mario Schubert, James C. Paulson, Jesús Jiménez-Barbero, June Ereño-Orbea
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Visible Light Control over the Cytolytic Activity of a Toxic Pore-Forming Protein ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-06 Jana Volarić, Nieck J. van der Heide, Natalie L. Mutter, Douwe F. Samplonius, Wijnand Helfrich, Giovanni Maglia, Wiktor Szymanski, Ben L. Feringa
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Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-05 Markus Zehe, Josef Kehrein, Curd Schollmayer, Christina Plank, Helena Kovacs, Eduardo Merino Asumendi, Ulrike Holzgrabe, Clemens Grimm, Christoph Sotriffer
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RNA-Binding Peptides Inspired by the RNA Recognition Motif ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-05 Luke K. Marshall, Albert C. Fahrenbach, Pall Thordarson
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Bioluminescent Intercalating Dyes for Ratiometric Nucleic Acid Detection ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-05 Yosta de Stigter, Harmen J. van der Veer, Bas J. H. M. Rosier, Maarten Merkx
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Synthesis and Properties of RNA Modified with Cationic Amine Internucleoside Linkage ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-05 Chandan Pal, Michael Richter, Eriks Rozners
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Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-02 Seong Ho Hong, Anand Divakaran, Akane Osa, Oscar W. Huang, Ingrid E. Wertz, Daniel K. Nomura
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Acylation of MLKL Impacts Its Function in Necroptosis ACS Chem. Biol. (IF 4.0) Pub Date : 2024-02-01 Apoorva J. Pradhan, Shweta Chitkara, Ricardo X. Ramirez, Viviana Monje-Galvan, Yasemin Sancak, G. Ekin Atilla-Gokcumen
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Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-31 Yi Lien, Jake C. Lachowicz, Aigera Mendauletova, Cynthia Zizola, Thacien Ngendahimana, Anastasiia Kostenko, Sandra S. Eaton, John A. Latham, Tyler L. Grove
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Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-31 Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R. Schneider, Xin Zhang, Lena M. Berger, Benedict-Tilman Berger, Martin P. Schwalm, Nick A. Klopp, Jens T. Siveke, Stefan Knapp, Andreas C. Joerger
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Laboratory Evolution of Metalloid Reductase Substrate Recognition and Nanoparticle Product Size ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-31 Alexander R. Hendricks, Rachel S. Cohen, Gavin A. McEwen, Tony Tien, Bradley F. Guilliams, Audrey Alspach, Christopher D. Snow, Christopher J. Ackerson
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Activity of Gut-Derived Nisin-like Lantibiotics against Human Gut Pathogens and Commensals ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-31 Zhenrun J. Zhang, Chunyu Wu, Ryan Moreira, Darian Dorantes, Téa Pappas, Anitha Sundararajan, Huaiying Lin, Eric G. Pamer, Wilfred A. van der Donk
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Improving Split Reporters of Protein–Protein Interactions through Orthology-Based Protein Engineering ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-30 Louise-Marie Rakotoarison, Alison G. Tebo, Dorothea Böken, Stephanie Board, Lina El Hajji, Arnaud Gautier
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Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-30 Audrey E. Yñigez-Gutierrez, Jennifer E. Wurm, Jordan T. Froese, Nicholas E. Rosenthal, Brian O. Bachmann
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Identification of Low-Density Lipoprotein Receptor-Related Protein 1 as a CXCL14 Receptor Using Chemically Synthesized Tetrafunctional Probes ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-30 Rin Miyajima, Kosuke Tanegashima, Naoto Naruse, Masaya Denda, Takahiko Hara, Akira Otaka
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Trifunctional Sphinganine: A New Tool to Dissect Sphingolipid Function ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-29 Scotland Farley, Frank Stein, Per Haberkant, Fikadu G. Tafesse, Carsten Schultz
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Expanding the Genetic Code of Xenopus laevis Embryos ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-26 Wes Brown, Lance A. Davidson, Alexander Deiters
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A Tandem-Affinity Purification Method for Identification of Primary Intracellular Drug-Binding Proteins ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-25 Sehbanul Islam, Jitendra Gour, Thomas Beer, Hsin-Yao Tang, Joel Cassel, Joseph M. Salvino, Luca Busino
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Forward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-25 Anderson R. Frank, Florentina Vandiver, David G. McFadden
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Ubiquitin-Derived Fragment as a Peptide Linker for the Efficient Cleavage of a Target Protein from a Degron ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-25 Yuki Utsugi, Ken Nishimura, Satoshi Yamanaka, Kohei Nishino, Hidetaka Kosako, Tatsuya Sawasaki, Hideyuki Shigemori, Thomas J. Wandless, Yusaku Miyamae
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Mitochondria-Associated Transcriptome Profiling via Localizable Aggregation-Induced Emission Photosensitizers in Live Cells ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-24 Jiying Liang, Jinghua Han, Yuan Zhuang, GuanHua Chen, Ying Li
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Omniligase-1-Mediated Phage-Peptide Library Modification and Insulin Engineering ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-24 Yi Wolf Zhang, Nai-Pin Lin, Xu Guo, Nicolas Szabo-Fresnais, Peter J. Ortoleva, Danny Hung-Chieh Chou
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Interbacterial Biofilm Competition through a Suite of Secreted Metabolites ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-23 Soniya Rayi, Yanyao Cai, Jennifer L. Greenwich, Clay Fuqua, Joseph P. Gerdt
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Inosine-Induced Base Pairing Diversity during Reverse Transcription ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-22 Ya Ying Zheng, Kaalak Reddy, Sweta Vangaveti, Jia Sheng
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Sustainable B12-Dependent Dehalogenation of Organohalides in E. coli ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-22 Tai L. Ng, Pamela A. Silver
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Correction to “Analysis of the Sequence Preference of Saporin by Deep Sequencing” ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-22 Samuel Hauf, Rachapun Rotrattanadumrong, Yohei Yokobayashi
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Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-20 Ram Jha, Alexander Kinna, Alastair Hotblack, Reyisa Bughda, Anna Bulek, Isaac Gannon, Tudor Ilca, Christopher Allen, Katarina Lamb, Abigail Dolor, Ian Scott, Farhaan Parekh, James Sillibourne, Shaun Cordoba, Shimobi Onuoha, Simon Thomas, Mathieu Ferrari, Martin Pule
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Introducing Our Authors ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-19 Katie Nieves
This article has not yet been cited by other publications.
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Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-18 Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
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Multiplex, Quantitative, High-Resolution Imaging of Protein:Protein Complexes via Hybridization Chain Reaction ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-17 Samuel J. Schulte, Boyoung Shin, Ellen V. Rothenberg, Niles A. Pierce
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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-17 Nadide Altincekic, Nathalie Jores, Frank Löhr, Christian Richter, Claus Ehrhardt, Marcel J. J. Blommers, Hannes Berg, Sare Öztürk, Santosh L. Gande, Verena Linhard, Julien Orts, Marie Jose Abi Saad, Matthias Bütikofer, Janina Kaderli, B. Göran Karlsson, Ulrika Brath, Mattias Hedenström, Gerhard Gröbner, Uwe H. Sauer, Anastassis Perrakis, Julian Langer, Lucia Banci, Francesca Cantini, Marco Fragai,
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Systematic Evaluation of Protein-Small Molecule Hybrids on the Yeast Surface ACS Chem. Biol. (IF 4.0) Pub Date : 2024-01-17 Manjie Huang, Marina Rueda-Garcia, Abbigael Harthorn, Benjamin J. Hackel, James A. Van Deventer