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Emerging peptide science in the United Kingdom Pept. Sci. (IF 1.865) Pub Date : 2021-01-25 Andrew G. Jamieson
It is with great pleasure that I present this special issue of Peptide Science focused on the state‐of‐the‐art in peptide research from laboratories in the UK. This issue is the fifth of an international series of special issues that highlights Emerging Peptide Science research from countries with an active community of scientists working in the field. The previous issues have covered recent scientific
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Bestrophin‐derived peptide, WP17, elicits cell wall disruption‐mediated bactericidal activity against Micrococcus luteus and anti‐neoplastic effect against murine melanoma cells Pept. Sci. (IF 1.865) Pub Date : 2021-01-22 Gayathri Ravichandran; Stefi V. Raju; Purabi Sarkar; Saraswathi N. T.; Ebtesam M. Al Olayan; Abeer S. Aloufi; Mohamed A. Elokaby; Aziz Arshad; Kanchana Mala; Jesu Arockiaraj
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Design and characterization of a surfactant‐conjugated, long‐acting, balanced GLP‐1/glucagon receptor dual agonist Pept. Sci. (IF 1.865) Pub Date : 2021-01-22 John J. Nestor; Xiaoming Zhang; Sarah Jaw‐Tsai; David G. Parkes; Cyrus K. Becker
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Stapled ACE2 peptidomimetics designed to target the SARS‐CoV‐2 spike protein do not prevent virus internalization Pept. Sci. (IF 1.865) Pub Date : 2021-01-08 Danielle C. Morgan; Caroline Morris; Amit Mahindra; Connor M. Blair; Gonzalo Tejeda; Imogen Herbert; Matthew L. Turnbull; Gauthier Lieber; Brian J. Willett; Nicola Logan; Brian Smith; Andrew B. Tobin; David Bhella; George Baillie; Andrew G. Jamieson
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Capturing nested information from disordered peptide phases Pept. Sci. (IF 1.865) Pub Date : 2020-12-21 Christella K. Gordon; Regina Luu; David Lynn
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The future of peptide science: Recognizing the American Peptide Society's Young Investigators Pept. Sci. (IF 1.865) Pub Date : 2020-11-28 Michael A. Bertucci; Katelyn J. Smith
The American Peptide Society (APS) has a long tradition of recognizing and supporting graduate and postdoctoral students who are conducting research in the field of peptide science. These emerging leaders, whom we affectionately refer to as Young Investigators (YIs), were represented in large numbers at the 26th American Peptide Symposium in Monterey Bay, California, USA in 2019. Understanding the
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Flow‐based SPPS for protein synthesis: A perspective Pept. Sci. (IF 1.865) Pub Date : 2020-10-06 Zachary P. Gates; Nina Hartrampf
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Recent developments in catalytic amide bond formation Pept. Sci. (IF 1.865) Pub Date : 2020-11-16 Mihajlo Todorovic; David M. Perrin
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Short self‐assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials Pept. Sci. (IF 1.865) Pub Date : 2020-11-21 Hiroshi Tsutsumi; Kunifumi Tanaka; Jyh Yea Chia; Hisakazu Mihara
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Functionalized peptide hydrogels as tunable extracellular matrix mimics for biological applications Pept. Sci. (IF 1.865) Pub Date : 2020-10-26 Katharina S. Hellmund; Benjamin von Lospichl; Christoph Böttcher; Kai Ludwig; Uwe Keiderling; Laurence Noirez; Annika Weiß; Dorian J. Mikolajczak; Michael Gradzielski; Beate Koksch
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Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes Pept. Sci. (IF 1.865) Pub Date : 2020-10-26 Uru Malik; Lai Yue Chan; Minying Cai; Victor J. Hruby; Quentin Kaas; Norelle L. Daly; David J. Craik
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Structural diversity in de novo cyclic peptide ligands from genetically encoded library technologies Pept. Sci. (IF 1.865) Pub Date : 2020-10-28 Tom E. McAllister; Oliver D. Coleman; Grace Roper; Akane Kawamura
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Introduction of cell‐selectivity in bovine cathelicidin BMAP‐28 by exchanging heptadic isoleucine with the adjacent proline at a non‐heptadic position Pept. Sci. (IF 1.865) Pub Date : 2020-10-23 Sarfuddin Azmi; Neeraj Kumar Verma; Jitendra Kumar Tripathi; Saurabh Srivastava; Devesh Pratap Verma; Jimut Kanti Ghosh
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μ‐Conotoxin KIIIA peptidomimetics that block human voltage‐gated sodium channels Pept. Sci. (IF 1.865) Pub Date : 2020-10-24 Astrid Knuhtsen; Rachel Whiting; Fergus S. McWhinnie; Charlotte Whitmore; Brian O. Smith; A. Christopher Green; Christopher M. Timperley; Kenneth I. Kinnear; Andrew G. Jamieson
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Structure of neuroendocrine regulatory peptide‐2 in membrane‐mimicking environments Pept. Sci. (IF 1.865) Pub Date : 2020-10-19 One‐Sung Park; Jeong Kyu Bang; Kyoung‐Seok Ryu; Eunha Hwang; Kwan Soo Hong; Youngjoo Byun; Chaejoon Cheong; Young Ho Jeon
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Self‐assembly of hairpin peptides mediated by Cu(II) ion: Effect of amino acid sequence Pept. Sci. (IF 1.865) Pub Date : 2020-10-17 Jiqian Wang; Chengdong Wang; Yanqing Ge; Yawei Sun; Dong Wang; Hai Xu
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Dual‐peptide functionalized nanoparticles for therapeutic use Pept. Sci. (IF 1.865) Pub Date : 2020-10-15 Chelsea R. Forest; Caitlin A. C. Silva; Pall Thordarson
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Designing stapled peptides to inhibit protein‐protein interactions: An analysis of successes in a rapidly changing field Pept. Sci. (IF 1.865) Pub Date : 2020-10-12 Marie T. J. Bluntzer; James O'Connell; Terry S. Baker; Julien Michel; Alison N. Hulme
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Cyclic dipeptides: Biological activities and self‐assembled materials Pept. Sci. (IF 1.865) Pub Date : 2020-10-10 Kaili Zhao; Ruirui Xing; Xuehai Yan
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Bioactivity improvement via display of the hydrophobic core of HYD1 in a cyclic β‐hairpin‐like scaffold, MTI‐101 Pept. Sci. (IF 1.865) Pub Date : 2020-10-09 Priyesh Jain; David B. Badger; Yi Liang; Anthony W. Gebhard; Daniel Santiago; Philip Murray; Sridhar R. Kaulagari; Ted J. Gauthier; Rajesh Nair; MohanRaja Kumar; Wayne C. Guida; Lori A. Hazlehurst; Mark L. McLaughlin
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Effect of side chain phenyl group on the self‐assembled morphology of dipeptide hydrazides Pept. Sci. (IF 1.865) Pub Date : 2020-10-06 Taku Ohtomi; Sayuri L Higashi; Daisuke Mori; Aya Shibata; Yoshiaki Kitamura; Masato Ikeda
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Synergy among humimycins against methicillin‐resistant Staphylococcus aureus Pept. Sci. (IF 1.865) Pub Date : 2020-10-01 Robert J. Tancer; Kazim Baynes; Gregory R. Wiedman
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Engineering and characterization of a pH‐sensitive homodimeric antiparallel coiled coil Pept. Sci. (IF 1.865) Pub Date : 2020-08-14 Radhika P. Nagarkar; Galit Fichman; Joel P. Schneider
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Synthesis of C‐terminal glycine‐rich o‐aminoanilide peptides without overacylation for use in benzotriazole‐mediated native chemical ligation Pept. Sci. (IF 1.865) Pub Date : 2020-09-23 Fernando J. Ferrer‐Gago; Li Quan Koh
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Self‐assembling cyclic peptide‐oligonucleotide conjugates: Synthetic strategies and the effect of cyclic topology on self‐assembly and base pairing Pept. Sci. (IF 1.865) Pub Date : 2020-09-23 Mahnseok Kye; Zhihao Zhang; Yong‐beom Lim
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Peptides as key components in the design of non‐viral vectors for gene delivery Pept. Sci. (IF 1.865) Pub Date : 2020-09-18 Joseph Thomas; Kamia Punia; Jin Kim Montclare
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Piezoelectric properties reflecting nanostructures of tetrathiafulvalene and chloranil complexes using cyclic peptide nanotube scaffolds Pept. Sci. (IF 1.865) Pub Date : 2020-09-16 Hiroshi Ohmura; Yuki Tabata; Shunsaku Kimura; Hirotaka Uji
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Antibacterial and antibiofilm efficacy of synthetic polymyxin‐mimetic lipopeptides Pept. Sci. (IF 1.865) Pub Date : 2020-09-12 Rawan Huwaitat; Sophie M. Coulter; Simon L. Porter; Sreekanth Pentlavalli; Garry Laverty
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A comparison of the collagen triple helix and coiled‐coil peptide building blocks on metal ion‐mediated supramolecular assembly Pept. Sci. (IF 1.865) Pub Date : 2020-09-10 Ryan W. Curtis; Jean Chmielewski
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Simulation of differential structure and dynamics of disulfide bond isoforms of conopeptide AuIB in presence of human α3β4 nAChR Pept. Sci. (IF 1.865) Pub Date : 2020-08-07 Karuna Anna Sajeevan; Durba Roy
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Fluorinated peptide biomaterials Pept. Sci. (IF 1.865) Pub Date : 2020-07-28 Janna N. Sloand; Michael A. Miller; Scott H. Medina
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Dedicated to a peptide chemist of few words and immense impact: Louis A. Carpino Pept. Sci. (IF 1.865) Pub Date : 2020-07-25 Lila M. Gierasch; Fernando Albericio; Claudio Toniolo
This issue of Peptide Science is a testimonial to brilliance packaged in a nontraditional way. We are honoring the contributions of Louis A. Carpino (“Lou” to many of us or “Louie” to a few), who passed away in January 2019 at the age of 91. Lou Carpino's contributions to peptide chemistry specifically, and organic chemistry more broadly, over the course of his career are truly stunning as summarized
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Nanostructures from protected L/L and D/L amino acid containing dipeptides Pept. Sci. (IF 1.865) Pub Date : 2020-06-17 Rajat Subhra Giri; Saikat Pal; Sayanta Roy; Gobinda Dolai; Srinivasa Rao Manne; Sandip Paul; Bhubaneswar Mandal
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Enzymatically forming cell compatible supramolecular assemblies of tryptophan‐rich short peptides Pept. Sci. (IF 1.865) Pub Date : 2020-06-02 Dongsik Yang; Beom Jin Kim; Hongjian He; Bing Xu
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In Memoriam Pept. Sci. (IF 1.865) Pub Date : 2020-05-27 Ved Srivastava
Unfortunately, over the last 12 months, the peptide science community has lost several colleagues, notably, Judy Warner, American Peptide Society (APS) Symposium organizer, Elizabeth Schram, the American Peptide Symposium Young Investigator sponsor, and Professor Jean Rivier, the president of the APS (1993‐1995). Judy was a wonderful person, always gentle and cheerful, and dedicated to the organization
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Structural studies and cyclization of the neuroprotective octapeptide NAPVSIPQ to improve cell permeability Pept. Sci. (IF 1.865) Pub Date : 2020-07-11 Dawn Ernenwein, Sarah E. St. John, Alistair J. Stewart, Bruce H. Morimoto, Jean Chmielewski, Mark A. Lipton
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Using 19F NMR and two‐level factorial design to explore thiol‐fluoride substitution in hexafluorobenzene and its application in peptide stapling and cyclisation Pept. Sci. (IF 1.865) Pub Date : 2020-07-09 Paolo Dognini; Patrick M. Killoran; George S. Hanson; Lewis Halsall; Talhat Chaudhry; Zasharatul Islam; Francesca Giuntini; Christopher R. Coxon
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Fluorescent cyclic peptides for cell imaging Pept. Sci. (IF 1.865) Pub Date : 2020-07-02 Lorena Mendive‐Tapia; Jinling Wang; Marc Vendrell
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Proteomimetic zinc finger domains with modified metal‐binding β‐turns Pept. Sci. (IF 1.865) Pub Date : 2020-06-07 Shilpa R. Rao; W. Seth Horne
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Development of a fluorescent three‐hybrid system for the identification of protein‐protein associators Pept. Sci. (IF 1.865) Pub Date : 2020-06-05 Andrew D. Foster; Chun‐wa Chung; Michael M. Hann; Graham L. Simpson; Ali Tavassoli
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Targeting of peptide‐binding receptors on cancer cells with peptide‐drug conjugates Pept. Sci. (IF 1.865) Pub Date : 2020-05-13 Dennis J. Worm, Sylvia Els‐Heindl, Annette G. Beck‐Sickinger
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How to overcome endosomal entrapment of cell‐penetrating peptides to release the therapeutic potential of peptides? Pept. Sci. (IF 1.865) Pub Date : 2020-05-07 Ferran Nadal‐Bufí; Sónia Troeira Henriques
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Wash‐free, peptide‐based fluorogenic probes for microbial imaging Pept. Sci. (IF 1.865) Pub Date : 2020-05-07 Assel Baibek; Muhammed Üçüncü; Elizabeth A. Blackburn; Mark Bradley; Annamaria Lilienkampf
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Modifying the surface of peptide nanofibers utilizing a thiol‐thioester exchange Pept. Sci. (IF 1.865) Pub Date : 2020-04-29 Ramiz Haddad; Elizabeth Ferraro; Ashley Halmans; Jillian E. Smith‐Carpenter
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Effect of residue insertion on the stability of polyproline‐I and II structures: Circular dichroism spectroscopic analyses of block‐type oligo‐prolines (Pro)m‐Gly/Ala‐(Pro)n Pept. Sci. (IF 1.865) Pub Date : 2020-04-27 Sachiro Kakinoki; Makoto Kitamura; Yuri Noguchi; Yuki Arichi
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Therapeutic peptides targeting the Ras superfamily Pept. Sci. (IF 1.865) Pub Date : 2020-04-13 Catherine A. Hurd; Helen R. Mott; Darerca Owen
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Total synthesis of bovine pancreatic trypsin inhibitor and the protein diastereomer [Gly37D‐Ala]BPTI using Boc chemistry solid phase peptide synthesis Pept. Sci. (IF 1.865) Pub Date : 2020-04-11 Alexander J. Donovan, Joanna Dowle, Yanwu Yang, Michael A. Weiss, Stephen B. H. Kent
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Proline‐to‐cysteine cyclization for generating conformationally constrained cyclic peptides Pept. Sci. (IF 1.865) Pub Date : 2020-04-10 John R. Frost, Jake Z. Essman, Chunhui Huang, Nicholas A. Pierson, Natalya Pissarnitski, Tao Meng
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Carpino's protecting groups, beyond the Boc and the Fmoc Pept. Sci. (IF 1.865) Pub Date : 2020-04-10 Ayman El‐Faham, Fernando Albericio
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Comparison between clickable cyclic TAT and penetratin for delivery of cyclic and bicyclic‐peptide cargos Pept. Sci. (IF 1.865) Pub Date : 2020-03-31 Ketav Kulkarni, Jianrong Sang, Xiuquan Ma, Jacqueline A. Wilce
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Investigation of the structure‐activity relationship in ponericin L1 from Neoponera goeldii Pept. Sci. (IF 1.865) Pub Date : 2020-03-31 Alexandria S. Senetra, Matthew R. Necelis, Gregory A. Caputo
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Design, synthesis and evaluation of E2‐25K derived stapled peptides Pept. Sci. (IF 1.865) Pub Date : 2020-03-24 Morag E. Watson; Daniel Scott; Craig Jamieson; Robert Layfield; Andrew M. Mason
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One‐pot peptide cleavage and macrocyclization through direct amidation using triazabicyclodecene Pept. Sci. (IF 1.865) Pub Date : 2020-03-24 Jennifer L. Hickey, Songnian Lin
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Cover Image, Volume 112, Issue 2 Pept. Sci. (IF 1.865) Pub Date : 2020-03-23 Takahiro Takekiyo, Natsuki Yamada, Taku Amo, Yukihiro Yoshimura
Cover caption: The aggregation behaviour of peptide fragments of proteins in aqueous solutions with ionic liquids (ILs) could help identify the relationship between IL–protein interactions and structural behaviour of intrinsically disordered proteins in this media. Takekiyo et al. report that the addition of 1‐butyl‐3‐methylimidazolium thiocyanate, but not ethylammonium nitrate, to amyloid β1–11 peptide
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On‐resin microwave‐assisted copper‐catalyzed azide‐alkyne cycloaddition of H1‐relaxin B single chain ‘stapled’ analogues Pept. Sci. (IF 1.865) Pub Date : 2020-03-23 Annunziata D'Ercole, Giuseppina Sabatino, Lorenzo Pacini, Elisa Impresari, Ilaria Capecchi, Anna Maria Papini, Paolo Rovero