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Unravelling Post-harvest Ripening Metabolomics of a New White Variety Guava Fruit (Cv Arka Mridula) with Special Emphasis on Phenolics and Corresponding Antioxidants Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-16 Yatheesharadhya Bylappa, Anish Nag
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The Potential of Fish Protein Hydrolysate Supplementation in Nile Tilapia Diets: Effects on Growth and Health Performance, Disease Resistance, and Farm Economic Analysis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-15 Muhammad Anamul Kabir, Shishir Kumar Nandi, Afrina Yeasmin Suma, Zulhisyam Abdul Kari, Suniza Anis Mohamad Sukri, Lee Seong Wei, Abdullah Al Mamun, Paul Seguin, Mikael Herault, Martina Irwan Khoo, Guillermo Téllez-Isaías
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SNORD45A Affects Content of HIF-1α and Promotes Endothelial Angiogenic Function Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-15 Xi Yang, Meng Li, Hongqiao Wang, Mengyuan Wang, Yiming Liu, Wenhua Xu, Tao Jiang
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Modulation of T Cell Differentiation in Mice with COPD Combined with Lung Cancer Through Key Targets of PD-1 by Tao Hong Si Wu Tang Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-15 Guoli Wang, Ge Wang, Keming Zhao, Aifeng Sui, Lina Wang, Yanling Xu, Nini Qu, Xiande Ma, Hu Deng
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Biofabricated Green Synthesized Hibiscus Silver Nanoparticles Potentiate Antibacterial Activity and Cytotoxicity in Human Lung Cancer Cells Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-14 Bharti Ahirwar, Dheeraj Ahirwar, Ritesh Jain, Bhagyashri Agrawal, Parvin Sahu, Kalyani Sakure, Hemant Badwaik
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Effects of Hydrothermal Pretreatment and Anaerobic Digestion of Pig Manure on the Antibiotic Removal and Methane Production Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-14 Chunchun Guo, Yanfang Ma, Yitao Li, Zhiwu Wang, Shupeng Lin, Renjie Dong, Shan Liu
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Rutaecarpine Protects Against Cigarette Smoke–Induced Chronic Obstructive Pulmonary Disease (COPD) in Rats Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-14 Zexuan Ji, Changhong Zhang, Ping Feng, Jianqing Zhao
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Bone Marrow-Derived C-Kit+ Cells Improved Inflammatory IL-33/ST-2/ILC2 Axis in the Lung Tissue of Type 2 Diabetic Rats Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-13
Abstract Inflammation is an essential factor in pulmonary complications of diabetes. Bone marrow (BM)-derived C-kit+ cells have immunomodulatory properties and their transplantation is suggested as a promising strategy for ameliorating diabetes complications. This study evaluated the effect of BM-derived C-kit+ cells on the inflammation signaling pathway in lung tissue of type 2 diabetic male rats
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An Evidence of Carbonic Anhydrase Activity in Native Microalgae for CO2 Capture Application Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-13 MubarakAli Davoodbasha, Naveenkumar Kathiravan, Akash Jayakannan, Sathya Raghunathan, Jung-Wan Kim, Thajuddin Nooruddin
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Causal Association of Telomere Length and Loss of Bone: a Directional Mendelian Randomization Study of Multi-Outcomes Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-13 Xiaoxun Du, Cunliang Guo, Chao Zhang, Baoshan Xu
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Toxic Impact of Sheathmar on Oreochromis mossambicus: A Comprehensive Biomarker Analysis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-13 Sharmistha Medda, Ritwick Bhattacharya, Sarmila Pal, Nimai Chandra Saha
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Understanding the Dynamics of Human Defensin Antimicrobial Peptides: Pathogen Resistance and Commensal Induction Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-13
Abstract Antimicrobial peptides (AMPs), also known as host defense peptides, are petite molecules with inherent microbicidal properties that are synthesized by the host’s innate immune response. These peptides serve as an initial barrier against pathogenic microorganisms, effectively eliminating them. Human defensin (HD) AMPs represent a prominent group of peptides involved in the innate immune response
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Bioinformatics Analysis and Experimental Validation for Exploring Key Molecular Markers for Glioblastoma Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-06 Zhenchao Huang, Zhijie Chen, En’peng Song, Peng Yu, Weiwen Chen, Huiqin Lin
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Investigation of In Vitro Anti-cancer and Apoptotic Potential of Onion-Derived Nanovesicles Against Prostate and Cervical Cancer Cell Lines Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-03-05 Vinayak Sharma, Eshu Singhal Sinha, Jagtar Singh
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Enhancing L-Asparagine Bioproduction Efficiency Through L-Asparagine Synthetase and Polyphosphate Kinase-Coupled Conversion and ATP Regeneration Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-02-15 Zijia Wei, Yuhua Zhang, Xuguo Duan, Yucheng Fan
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Role of Structural Peculiarities of Flavonoids in Suppressing AGEs Generated From HSA/Glucose System Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-02-14 Alireza Mohammadpour, Morteza Sadeghi, Mehran Miroliaei
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Development of a Competitive Chemiluminescent Assay for Quantitative Determination of TP53 Fusion Protein Using Reagent Strips Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-02-14 Linyu Wang, Zhifang He, Jianye Li
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Lactobacillus rhamnosus and Lactobacillus delbrueckii Ameliorate the Expression of miR-125a and miR-146a in Systemic Lupus Erythematosus Patients Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-02-14
Abstract The microRNAs are non-coding RNA molecules involved in physiological and pathological processes, causing autoimmune diseases such as systemic lupus erythematosus (SLE). Probiotics are living microorganisms that possess beneficial effects on the host immune system and modulate it. The effect of Lactobacillus rhamnosus and Lactobacillus delbrueckii on the expression of miR-125a and miR-146a
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Targeting Efficient Features of Urate Oxidase to Increase Its Solubility Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-02-03 Mohammad Reza Rahbar, Navid Nezafat, Mohammad Hossein Morowvat, Amir Savardashtaki, Mohammad Bagher Ghoshoon, Kamran Mehrabani-Zeinabad, Younes Ghasemi
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Explore Key Genes and Mechanisms Involved in Colon Cancer Progression Based on Bioinformatics Analysis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-31 Yongting Lan, Xiuzhen Yang, Yulian Wei, Zhaobing Tian, Lina Zhang, Jian Zhou
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Mesenchymal Stem Cell-Induced Neuroprotection in Pediatric Neurological Diseases: Recent Update of Underlying Mechanisms and Clinical Utility Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-23
Abstract Pediatric neurological diseases refer to a group of disorders that affect the nervous system in children. These conditions can have a significant impact on a child’s development, cognitive function, motor skills, and overall quality of life. Stem cell therapy is a new and innovative approach to treat various neurological conditions by repairing damaged neurons and replacing those that have
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Melitoxin Inhibits Proliferation, Metastasis, and Invasion of Glioma U251 Cells by Down-regulating F2RL1 Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-22 Peng Xu, Jie Zhou, Xiaohui Xing, Yuan Hao, Mingxu Gao, Zhongchen Li, Xin Li, Mengyou Li, Yilei Xiao
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Plasma MCP-1 and TGF-β1 Levels are Associated with Kidney Injury in Children with Congenital Anomalies of the Kidney and Urinary Tract Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-20 XiaoQi Xuan, Xiao Pu, Yue Yang, JinLong Yang, YongLe Li, Hang Wu, JianGuo Xu
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Waste Sludge: Entirely Waste or a Sustainable Source of Biocrude? A Review Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-18
Abstract Biomass-derived biocrude is gaining greater recognition from people in general as an alternative fuel source to traditional fossil fuels. Worldwide, a great deal of research is being done to develop fuels made from sustainable biomass in order to replace the current conventional energy sources. Waste sludge has been thought of as a viable raw biomass source because of its accessibility, affordability
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Treatment of Intracerebral Hemorrhage with Traditional Chinese Medicine Monomer Wogonin by Modifying NLRP3 with METTL14 to Inhibit Neuronal Cell Pyroptosis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-15 Libo Li, Jinbing Gong, Wenjia Zhang
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Th9 Cytokines Inhibit Proliferation, Promote Apoptosis, and Immune Escape in Thyroid Carcinoma Cells Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-15
Abstract To investigate the regulatory effects of T helper 9 (Th9) cytokines on the proliferation, apoptosis and immune escape of thyroid cancer cells. The survival rate of human thyroid cancer cell line TPC-1 after treatment with 0, 1, 2.5, 5, 10, 20 ng/ml IL-9 (or IL-21) was determined by CCK-8 method and suitable concentrations of IL-9 and IL-21 were screened out. The TPC-1 cells cultured in vitro
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Characterization of Collagen from Jellyfish Aurelia aurita and Investigation of Biomaterials Potentials Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-15 Elif Balikci, Erkan Türker Baran, Aydin Tahmasebifar, Bengi Yilmaz
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Melatonin as an Ameliorative Agent Against Cadmium- and Lead-Induced Toxicity in Fish: an Overview Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-15 Ashis Kumar Panigrahi, Palash Kumar Pal, Dipanwita Sarkar (Paria)
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Evaluation of Yield, Chemical Profile, and Antimicrobial Activity of Teucrium polium L. Essential Oil Used in Iranian Folk Medicine Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-09 Mansureh Ghavam, Fateme Sadat Markabi
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Characterization and Antioxidant Activity of the Polysaccharide Hydrolysate from Lactobacillus plantarum LPC-1 and Their Effect on Spinach (Spinach oleracea L.) Growth Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-09
Abstract This study presents a comparison between two hydrolysis systems (MnO2/H2O2 and ascorbic acid (VC)/H2O2) for the depolymerization of exopolysaccharide (EPS) from Lactobacillus plantarum LPC-1. Response surface methodology (RSM) was used to optimize these two degradation systems, resulting in two H2O2-free degradation products, MEPS (MnO2/H2O2-treated EPS) and VEPS (VC/H2O2-treated EPS), where
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Antifungal Activity Enhancement of Cell-Free Streptomyces griseus Extract Obtained by Fermentation with Magnetic Manganese Ferrite Nanoparticles Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-06 Liliana S. Farias-Vazquez, Rodolfo Ramos-González, Sandra Pacios-Michelena, Cristóbal N. Aguilar, Roberto Arredondo-Valdés, Raúl Rodríguez-Herrera, José L. Martínez-Hernández, Elda P. Segura-Ceniceros, Anna Ilyina
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Improved Short-Chain Fatty Acids Production and Protein Degradation During the Anaerobic Fermentation of Waste-Activated Sludge via Alumina Slag-Modified Biochar Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-06 Zijian Tang, Lin Chen, Yu Zhang, Ming Xia, Zhengzhong Zhou, Qian Wang, Huhe Taoli, Tao Zheng, Xiaoshan Meng
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POU Class 2 Homeobox Associating Factor 1, as a Hub Candidate Gene in OP, Relieves Osteoblast Apoptosis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-06 Xuepeng Wang, Chunchun Zou, Changju Hou, Maoqiang Li, Zhenyu Bian, Liulong Zhu
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Molecular Biology Applications of Psychrophilic Enzymes: Adaptations, Advantages, Expression, and Prospective Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-06 Hu Xu, Dawei Xu, Yongqin Liu
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A Broad-Spectrum α-Glucosidase of Glycoside Hydrolase Family 13 from Marinovum sp., a Member of the Roseobacter Clade Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-05 Jinling Li, Janice W.-Y. Mui, Bruna M. da Silva, Douglas E.V. Pires, David B. Ascher, Niccolay Madiedo Soler, Ethan D. Goddard-Borger, Spencer J. Williams
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An Overview of Crosslinked Enzyme Aggregates: Concept of Development and Trends of Applications Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-05 Oumaima Maroua Bouguerra, Roswanira Abdul Wahab, Fahrul Huyop, Abdo Mohammed Al-Fakih, Wan Muhd Asyraf Wan Mahmood, Naji Arafat Mahat, Mohd Khalizan Sabullah
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Recent Progress on Peroxidase Modification and Application Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-05 Chen Shen, Yongfa Wang
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Cancer-Associated Fibroblast-Secreted Exosomes Promote Gastric Cancer Cell Migration and Invasion via the IL-32/ESR1 Axis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-05 Lifeng Shang, Xinli Chen, Tianyu Zhu, Shujing Chong, Haiwang Liu, Wei Huang, Weibo Fu, Hao She, Xin Shen
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Luffa cylindrica (Sponge Gourd) Fibers in Treatment of Greywater: an Aerobic Fixed-Film Reactor Approach Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Upasana Arora, Himanshu Kumar Khuntia, H. N. Chanakya, Atya Kapley
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ω-3PUFAs Inhibit Hypoxia-Induced Retinal Neovascularization via Regulating Microglial Pyroptosis through METTL14-Mediated m6A Modification of IFNB1 mRNA Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Shun Wang, Jing Zhang, Jun Chen, Lanlan Tang, Min Ke, Yanni Xue, Ying He, Yan Gong, Zhi Li
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Rosmarinic Acid Liposomes Downregulate Hepcidin Expression via BMP6-SMAD1/5/8 Pathway in Mice with Iron Overload Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Cui-ling Jia, Bo-liang Li, Zi-hao Zhao, Zhi Zhang, Qi-Chen, Ji-Xian Song, Yujing Gou, Si-yu Gao, Chen-sha Sun, Yingna He, En-Sheng Ji, Yashuo Zhao
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Pros and Cons in Various Immobilization Techniques and Carriers for Enzymes Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Yong Jiang, Jinxia Zheng, Mengna Wang, Wanqi Xu, Yiquan Wang, Li Wen, Jian Dong
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PICALM as a Novel Prognostic Biomarker and Its Correlation with Immune Infiltration in Breast Cancer Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Naer A, Pengfei Lyu, Yue Yu, Meiling Liu, Shaohua Cheng, Meiyan Chen, Yunhong Liu, Xuchen Cao
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Pan-Cancer Analysis of P3H1 and Experimental Validation in Renal Clear Cell Carcinoma Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04
Abstract Prolyl 3-hydroxylase 1 (P3H1) has been implicated in cancer development, but no pan-cancer analysis has been conducted on P3H1. In this study, for the first time, aspects associated with P3H1, such as the mRNA expression, any mutation, promoter methylation, and prognostic significance, the relationship between P3H1 and clinicopathological parameters, drug sensitivity, and immune cell infiltration
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Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus paramycoides for In Vitro Biological Activities and In Vivo Assessment Against Hepatorenal Injury Induced by CCl4 in Rats Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Heba A. El-Refai, Alaa M. Saleh, Shimaa I. A. Mohamed, Asmaa F. Aboul Naser, Rania A. Zaki, Sanaa K. Gomaa, Manal A. Hamed
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Advances in RNA Interference for Plant Functional Genomics: Unveiling Traits, Mechanisms, and Future Directions Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04
Abstract RNA interference (RNAi) is a conserved molecular mechanism that plays a critical role in post-transcriptional gene silencing across diverse organisms. This review delves into the role of RNAi in plant functional genomics and its applications in crop improvement, highlighting its mechanistic insights and practical implications. The review begins with the foundational discovery of RNAi’s mechanism
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Bacterial nano-factories as a tool for the biosynthesis of TiO2 nanoparticles: characterization and potential application in wastewater treatment Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-04 Zahra Latifi Azizi, Sara Daneshjou
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Display of PETase on the Cell Surface of Escherichia coli Using the Anchor Protein PgsA Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02 Takuma Yamashita, Takuya Matsumoto, Ryosuke Yamada, Hiroyasu Ogino
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Inhibition of Integrin-Associated Kinases FAK and ILK on the In Vitro Model of Skin Wound Healing Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02
Abstract Dermal fibroblasts are essential cells of skin tissue responsible for its normal functioning. In skin wounds, the differentiation of resident fibroblasts into myofibroblasts occurs, which is accompanied by the rearrangement of actin cytoskeleton with the expression of alpha-smooth muscle actin. This transformation is a prerequisite for a successful wound healing. At the same time, different
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An Integrated Computational Approaches for Designing of Potential Piperidine based Inhibitors of Alzheimer Disease by Targeting Cholinesterase and Monoamine Oxidases Isoenzymes Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02 Muhammad Sarfraz, Muhammad Khurrum Ibrahim, Syeda Abida Ejaz, Hafiz Muhammad Attaullah, Mubashir Aziz, Mosab Arafat, Tahira Shamim, Muawya Elhadi, Tahira Ruby, Hafiz Kashif Mahmood
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Erianin Impedes the Proliferation and Metastatic Migration Through Suppression of STAT-3 Phosphorylation in Human Esophageal Cancer Cells Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02 Anxi Hu, Kunkun Li
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Proteomic Analysis of Collagen: a Mass Spectrometry Approach to Material Identification of Shadow Puppet Cultural Relics Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02 Yangbo Duan, Muzi Zhang, Chen Min, Yalun Lin, Li Li
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Effects of ADSC-Derived Exosome LRRC75A-AS1 on Anti-inflammatory Function After SCI Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2024-01-02 Xiaohui Xing, Peng Xu, Xiaoyang Xing, Zhentao Xu, Zhen Huang, Zhongchen Li, Xueyuan Li, Yilei Xiao
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Sphincter of Oddi Dysfunction Induces Gallstone by Inhibiting the Expression of ABCB11 via PKC-α Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30 Lichao Zhu, Wei Su, Xianwen Xu, Shuai Shao, Chuan Qin, Ruxin Gao, Xinxing Wang, Mingze Ma, Junlin Gao, Zhenhai Zhang
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NDRG2 Promotes Lens Epithelial Cells Senescence via NLRP3/Caspase1-Mediated Pyroptosis Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30 Huilan Zhang
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Occurrence Characteristics and Ecotoxic Effects of Microplastics in Environmental Media: a Mini Review Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30
Abstract The issue of environmental pollution caused by the widespread presence of microplastics (MPs) in environmental media has garnered significant attention. However, research on MPs pollution has mainly focused on aquatic ecosystems in recent years. The sources and pollution characteristics of MPs in the environment, especially in solid waste, have not been well-described. Additionally, there
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Myricetin Attenuates Ethylene Glycol-Induced Nephrolithiasis in Rats via Mitigating Oxidative Stress and Inflammatory Markers Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30 Xiaojie Yang, Pei Zhang, Jing Jiang, Hesham S. Almoallim, Sulaiman Ali Alharbi, Youfang Li
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Preparation, Structural Characterization, and Enzymatic Properties of Alginate Lyase Immobilized on Magnetic Chitosan Microspheres Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30
Abstract Alginate lyase is an enzyme that catalyses the hydrolysis of alginate into alginate oligoalginates. To enhance enzyme stability and recovery, a facile strategy for alginate lyase immobilization was developed. Novel magnetic chitosan microspheres were synthesized and used as carriers to immobilize alginate lyase. The immobilization of alginate lyase on magnetic chitosan microspheres was successful
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Unravelling the Untapped Pharmacological Potential of Plant Molecules as Inhibitors of BACE1: In Silico Explorations for Alzheimer’s Disease Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30
Abstract Alzheimer’s disease (AD) is an extremely complex, heterogeneous, and multifactorial neurodegenerative disease clinically characterized by progressive memory loss and progressive decline in cognitive function. There is currently no effective treatment for the onset and/or progression of the pathophysiological diseases of AD. The global prevalence of this disease has increased in recent years
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Valorization of Cheese Whey Powder by Two-Step Fermentation for Gluconic Acid and Ethanol Preparation Appl. Biochem. Biotechnol. (IF 3.0) Pub Date : 2023-12-30 Rui Zhang, Fan Li, Xinlu Liu, Xin Zhou, Kankan Jiang