-
Targeting Strategies for Site-Specific mRNA Delivery Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-16 Jiaxing Di, Pei Huang, Xiaoyuan Chen
-
Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-14 Aryn A. Alanizi, Alexandre M. Sorlin, Matthew F. L. Parker, Marina López-Álvarez, Hecong Qin, Sang Hee Lee, Joseph Blecha, Oren S. Rosenberg, Joanne Engel, Michael A. Ohliger, Robert R. Flavell, David M. Wilson
-
Development of an Engineered Single-Domain Antibody for Targeting MET in Non-Small Cell Lung Cancer Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-12 Natalie Y. Luo, Rachel L. Minne, Joseph P. Gallant, Gihan S. Gunaratne, Jayden L. West, Saahil Javeri, Austin J. Robertson, Eric W. Lake, Jonathan W. Engle, Jason C. Mixdorf, Eduardo Aluicio-Sarduy, Kwang P. Nickel, Reinier Hernandez, Randall J. Kimple, Andrew M. Baschnagel, Aaron M. LeBeau
-
Passivating the Background of Living Microbes with a Zwitterionic Peptide for Therapies Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-08 Liang Fang, Simian Cai, Patrick McMullen, Yi-Chen Hsu, Michelle Yi Qin Chen, Shaoyi Jiang
Living microbial therapies have been proposed as a course of action for a variety of diseases. However, problematic interactions between the host immune system and the microbial organism present significant clinical concerns. Previously, we developed a genetically encoded superhydrophilic zwitterionic peptide, termed EKP, to mimic low-immunogenic zwitterionic materials, which have been used for the
-
3-Acyl-4-Pyranone as a Lysine Residue-Selective Bioconjugation Reagent for Peptide and Protein Modification Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-07 Keyi Nong, Yi-Lu Zhao, Shandong Yi, Xuchun Zhang, Siyuan Wei, Zhu-Jun Yao
-
Transthyretin-Penetratin: A Potent Fusion Protein Inhibitor against Alzheimer’s Amyloid-β Fibrillogenesis with High Blood Brain Barrier Crossing Capability Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-07 Ying Wang, Wei Liu, Yan Sun, Xiaoyan Dong
-
Assessment of the Efficacy of the Combination of RNAi of lncRNA DANCR with Chemotherapy to Treat Triple Negative Breast Cancer Using Magnetic Resonance Molecular Imaging Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-06 Calin Nicolescu, Jiyoon Kim, Da Sun, Zheng-Rong Lu
-
GalNAc- or Mannose-PEG-Functionalized Polyplexes Enable Effective Lectin-Mediated DNA Delivery Bioconjugate Chem. (IF 4.7) Pub Date : 2024-03-05 Ricarda C. Steffens, Paul Folda, Nikole L. Fendler, Miriam Höhn, Katharina Bücher-Schossau, Susanne Kempter, Nicole L. Snyder, Laura Hartmann, Ernst Wagner, Simone Berger
-
Engineering the Propeptide of Microbial Transglutaminase Zymogen: Enabling Substrate-Dependent Activation for Bioconjugation Applications Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-29 Ryutaro Ariyoshi, Takashi Matsuzaki, Ryo Sato, Kosuke Minamihata, Kounosuke Hayashi, Taisei Koga, Kensei Orita, Riko Nishioka, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya
-
Amyloid β-Peptide Segment Conjugated Side-Chain Proline-Based Polymers as Potent Inhibitors in Lysozyme Amyloidosis Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-29 Kasturee Nayak, Pooja Ghosh, Soumen Barman, Babu Sudhamalla, Patrick Theato, Priyadarsi De
-
Recent Progress in Site-Selective Modification of Peptides and Proteins Using Macrocycles Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-28 Ye-Cheng Wang, Si-Cong Bai, Wei-Lin Ye, Jing Jiang, Gao Li
-
Interactions and Transport of a Bioconjugated Peptide Targeting the Mitomembrane Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-25 Son V. Nguyen, Lev Levintov, Roy P. Planalp, Harish Vashisth
-
Radiolabeling Diaminosarcophagine with Cyclotron-Produced Cobalt-55 and [55Co]Co-NT-Sarcage as a Proof of Concept in a Murine Xenograft Model Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-27 Wilson Lin, German Oscar Fonseca Cabrera, Eduardo Aluicio-Sarduy, Todd E. Barnhart, Jason C. Mixdorf, Zibo Li, Zhanhong Wu, Jonathan W. Engle
-
Synthetic and Computational Design Insights toward Mimicking Protein Binding of Phosphate Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-20 Whitney C. Fowler, Chuting Deng, O. Therese Teodoro, Juan J. de Pablo, Matthew V. Tirrell
-
A Kinetically Controlled Bioconjugation Method for the Synthesis of Radioimmunoconjugates and the Development of a Domain Mapping MS-Workflow for Its Characterization Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-17 Marco A. Pometti, Giuseppe Di Natale, Giancarlo Geremia, Nileshgiri Gauswami, Gianni Garufi, Giuseppina Ricciardi, Marcella Sciortino, Fabrizio Scopelliti, Giorgio Russo, Massimo Ippolito
-
pH-Responsive Amphiphilic Triblock Fluoropolymers as Assemble Oxygen Nanoshuttles for Enhancing PDT against Hypoxic Tumor Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-17 Jun-an Zhang, David Haddleton, Paul Wilson, Lin-hua Zhu, Chun-yan Dai, Lin-lu Zhao
-
Bioorthogonal Labeling Enables In Situ Fluorescence Imaging of Expressed Gas Vesicle Nanostructures Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-12 Erik Schrunk, Przemysław Dutka, Robert C. Hurt, Di Wu, Mikhail G. Shapiro
-
Cathepsin B Processing Is Required for the In Vivo Efficacy of Albumin–Drug Conjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-12 Barbara Bernardim, João Conde, Tuuli Hakala, Julie B. Becher, Mary Canzano, Aldrin V. Vasco, Tuomas P. J. Knowles, Jason Cameron, Gonçalo J. L. Bernardes
-
A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-11 Pei Zhu, Tianjie You, Ying Wang, Mingxue Ma, Sheng Ye, Si Liu
-
Peptide-Conjugated MRI Probe Targeted to Netrin-1, a Novel Metastatic Breast Cancer Biomarker Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-10 Clémentine Moreau, Tea Lukačević, Agnès Pallier, Julien Sobilo, Samia Aci-Sèche, Norbert Garnier, Sandra Même, Éva Tóth, Sara Lacerda
-
Micropreparative Gel Electrophoresis for Purification of Nanoscale Bioconjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-06 Sayyed Hashem Sajjadi, Shang-Jung Wu, Yahya Rabbani, Vitalijs Zubkovs, Hossein Ahmadzadeh, Elaheh K. Goharshadi, Ardemis A. Boghossian
-
A Spontaneous Assembling Lipopeptide Nanoconjugate Transporting the Anthracycline Drug N-Benzyladriamycin-14-valerate for Personalized Therapy of Ewing Sarcoma Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-06 Nirupama Sabnis, Sangram Raut, Bhavani Nagarajan, Ammar Kapic, Akpedje Serena Dossou, Leonard Lothstein, Rafal Fudala, Bruce A. Bunnell, Andras G. Lacko
-
[18F]pFBC, a Covalent CLIP-Tag Radiotracer for Detection of Viral Reporter Gene Transfer in the Murine Brain Bioconjugate Chem. (IF 4.7) Pub Date : 2024-02-03 Gregory D. Bowden, Sophie Stotz, Gina Dunkel, Sabrina Haas, Elena Kimmerle, Martin Schaller, Bettina Weigelin, Kristina Herfert, Bernd J. Pichler, Andreas Maurer
-
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-30 Jongmin Yum, Fadlina Aulia, Keisuke Kamiya, Mao Hori, Nan Qiao, Beob Soo Kim, Mitsuru Naito, Satomi Ogura, Tetsuya Nagata, Takanori Yokota, Satoshi Uchida, Satoshi Obika, Hyun Jin Kim, Kanjiro Miyata
-
Asymmetry of Dual-Display DNA-Encoded Chemical Libraries Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-24 Louise Plais, Louis Trachsel, Jörg Scheuermann
-
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody–Drug Conjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-24 Alan Zhang, Katherine Seiss, Laurent Laborde, Sebastian Palacio-Ramirez, Daniel Guthy, Mylene Lanter, Julien Lorber, Anna Vulpetti, Luca Arista, Thomas Zoller, Thomas Radimerski, Claudio Thoma, Christina Hebach, William R. Tschantz, Alexei Karpov, Gregory J. Hollingworth, Joseph A. D’Alessio, Stephane Ferretti, Matthew T. Burger
-
N-tert-Butoxycarbonyl-N-(2-(tritylthio)ethoxy)glycine as a Building Block for Peptide Ubiquitination Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-18 Lingling Peng, Elizabeth Helgason, Rafael Miranda, Jeffrey Tom, Jennifer Zhang, Erin C. Dueber, Aimin Song
-
An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-17 Anders Dinesen, Veronica L. Andersen, Marwa Elkhashab, Diego Pilati, Pernille Bech, Elisabeth Fuchs, Torbjørn R. Samuelsen, Alexander Winther, Yunpeng Cai, Anders Märcher, Archie Wall, Marjan Omer, Jesper S. Nielsen, Vijay Chudasama, James R. Baker, Kurt V. Gothelf, Jesper Wengel, Jørgen Kjems, Kenneth A. Howard
-
Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-12 Soyoung Yoon, Hyoung Eun Bae, Parameswaran Hariharan, Andreas Nygaard, Baoliang Lan, Menebere Woubshete, Aiman Sadaf, Xiangyu Liu, Claus J. Loland, Bernadette Byrne, Lan Guan, Pil Seok Chae
-
Palladium-Mediated S-Arylation of Cysteine Residues with 4-[18F]Fluoroiodobenzene ([18F]FIB) Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-12 Felix Francis, Melinda Wuest, Jenilee D. Woodfield, Frank Wuest
-
Exploring the Sensitivity of Antibody–Drug Conjugate Efficacy to the Selection of Payload, Antibody, and Cell line Bioconjugate Chem. (IF 4.7) Pub Date : 2024-01-03 Mara Rao, Shruthi Murali, Danielle Amores, Feifan Yu, Andrew Tsourkas
-
Contiguous Silver(I)-Mediated Base Pairs of Imidazophenanthroline and Canonical Nucleobases in DNA Duplexes: Formation of Classical Duplexes versus Homodimer Formation Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-29 Nils Lefringhausen, Catharina Erbacher, Matthias Elinkmann, Uwe Karst, Jens Müller
-
Aqueous Activation of RNA 2′-OH for Conjugation with Amines and Thiols Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-27 Ryuta Shioi, Lu Xiao, Eric T. Kool
-
DNA Nanostructures as Catalysts: Double Crossover Tile-Assisted 5′ to 5′ and 3′ to 3′ Chemical Ligation of Oligonucleotides Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-22 Andrea C. Bardales, Joseph R. Mills, Dmitry M. Kolpashchikov
-
Dual-Function Antibody Conjugate-Enabled Photoimmunotherapy Complements Fluorescence and Photoacoustic Imaging of Head and Neck Cancer Spheroids Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-21 Mohammad A. Saad, Stacey Grimaldo-Garcia, Allison Sweeney, Srivalleesha Mallidi, Tayyaba Hasan
-
Cleavage and Noncleavage Chemistry in Reactive Oxygen Species (ROS)-Responsive Materials for Smart Drug Delivery Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-20 Teng Chi, Ting Sang, Yanjing Wang, Zhou Ye
-
Enhancing Protective Antibodies against Opioids through Antigen Display on Virus-like Particles Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-19 Fatemeh Shafieichaharberoud, Shuyao Lang, Connor Whalen, Cristina Rivera Quiles, Lillie Purcell, Cameron Talbot, Pengfei Wang, Elizabeth B. Norton, Michelle Mazei-Robison, Agnieszka Sulima, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas, Xuefei Huang
-
Design Parameters for a Mass Cytometry Detectable HaloTag Ligand Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-19 Nicole Potter, Simon Latour, Edmond C. N. Wong, Mitchell A. Winnik, Hartland W. Jackson, Alison P. McGuigan, Mark Nitz
-
Photoswitchable Antibiotic Hybrids: Spacer Length-Dependent Photochemical Control of Antibacterial Activity Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-18 Supriya Bhunia, Arpan Das, Santosh Kumar Jana, Sukhendu Mandal, Subhas Samanta
-
Cyanopyridoimidazole/1,2-Aminothiol Click Reaction: A Novel Bioorthogonal Reaction for Synthesis of Radiotracers Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-18 Yi-Chen Sun, Wei-Xin Shi, Wei-Chieh Kuo, Yi-Rong Hsiang, Wei-Lin Lo, Liang-Cheng Chen, Shiou-Shiow Farn, Ya-Fan Lin, Kuo-Ting Chen
-
Precise Manipulation of the Site and Stoichiometry of Capsid Modification Enables Optimization of Functional Adeno-Associated Virus Conjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-16 Sarah B. Erickson, Quan Pham, Xiaofu Cao, Jake Glicksman, Rachel E. Kelemen, Seyed S. Shahraeini, Sebastian Bodkin, Zainab Kiyam, Abhishek Chatterjee
-
Coumarin-Conjugated Macromolecular Probe for Sequential Stimuli-Mediated Activation Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-13 Yu Jiang, Runqi Li, Fei Ren, Shuke Yang, Andong Shao
-
Crossing the Solubility Rubicon: 15-Crown-5 Facilitates the Preparation of Water-Soluble Sulfo-NHS Esters in Organic Solvents Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-12 Nicholas D. J. Yates, Connor G. Miles, Christopher D. Spicer, Martin A. Fascione, Alison Parkin
-
Brain-Penetrating Peptide Shuttles across the Blood–Brain Barrier and Extracellular-like Space Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-12 Xiujuan Peng, Xinquan Liu, Jae You Kim, Alex Nguyen, Jasmim Leal, Debadyuti Ghosh
-
Versatile Click Linker Enabling Native Peptide Release from Nanocarriers upon Redox Trigger Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-11 Erik R. Hebels, Stefanie Dietl, Matt Timmers, Jaimie Hak, Antionette van den Dikkenberg, Cristianne J.F. Rijcken, Wim E. Hennink, Rob M. J. Liskamp, Tina Vermonden
-
Molecular Recognition of Tyrosine-Containing Polypeptides with Pseudopeptidic Cages Unraveled by Fluorescence and NMR Spectroscopies Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-11 Naiara Solozabal, Lucía Tapia, Jordi Solà, Yolanda Pérez, Ignacio Alfonso
-
Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-06 Daan Sondag, Jurriaan J. A. Heming, Dennis W. P. M. Löwik, Elena Krivosheeva, Denise Lejeune, Mark van Geffen, Cornelis van’t Veer, Waander L. van Heerde, Marjolijn C. J. Beens, Brian H. M. Kuijpers, Thomas J. Boltje, Floris P. J. T. Rutjes
-
Multifunctional Poly(2-ethyl-2-oxazoline) Copolymers Containing Dithiolane and Pentafluorophenyl Esters as Effective Reactive Linkers for Gold Surface Coatings Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-06 Ondrej Sedlacek, Tim Egghe, Patricia Khashayar, Martin Purino, Paula Lopes, Jan Vanfleteren, Nathalie De Geyter, Richard Hoogenboom
-
In Vivo Comparative Study of Radioiodinated Folate Receptor Targeting Albumin Probes for Atherosclerosis Plaque Imaging Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-06 Xuejun Wen, Xueyuan Zeng, Jia Liu, Xinying Zeng, Yiren Zhang, Xingxing Cheng, Jinxiong Huang, Yesen Li, Rongqiang Zhuang, Xianzhong Zhang, Zhide Guo
-
Generation and Characterization of Iduronidase-Cleavable ADCs Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-06 Sebastian Jäger, Doreen Könning, Nicolas Rasche, Felix Hart, Janike Sensbach, Carina Krug, Sabine Raab-Westphal, Konstantin Richter, Carlo Unverzagt, Stefan Hecht, Jan Anderl, Christian Schröter
-
A Versatile Isocyanate-Mediated Strategy for Appending Chemical Tags onto Drug-Like Small Molecules Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-05 Catherine C. Henry, Jasmin A. Kruell, Robert M. Wilson, Chia-Fu Chang, Christina M. Woo, Angela N. Koehler
-
Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-05 Xiangdan Wang, Wenping Chang, Mehraban Khosraviani, Wilson Phung, Lingling Peng, Sivan Cohen, Benjamin T. Andrews, Yonglian Sun, Christopher W. Davies, James T. Koerber, Jihong Yang, Aimin Song
-
Characterization of an N-Allylglyoxylamide-Based Bioorthogonal Nitrone Trap Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-05 Daniel Lee, Simon Latour, Michael Emblem, Hunter J. Clark, Jobette T. Santos, Jaewan Jang, Alison P. McGuigan, Mark Nitz
-
Truncation-Free Genetic Code Expansion with Tetrazine Amino Acids for Quantitative Protein Ligations Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-04 Alex J. Eddins, Riley M. Bednar, Subhashis Jana, Abigail H. Pung, Lea Mbengi, Kyle Meyer, John J. Perona, Richard B. Cooley, P. Andrew Karplus, Ryan A. Mehl
-
Long-Term Strategies for Poorly Water-Soluble Peptides: Combining Fatty Acid Modification with PAS Fusion Bioconjugate Chem. (IF 4.7) Pub Date : 2023-12-01 Hongxiang Zhu, Haoju Hua, Yanzhen Dong, Jinhua Zhang, Hongjiang Xu, Xingfeng Ge, Qin Lu, Jun Feng
-
Multivalent Display of Erythropoietin on Quantum Dots Enhances Aquaporin-4 Expression and Water Transport in Human Astrocytes In Vitro Bioconjugate Chem. (IF 4.7) Pub Date : 2023-11-30 Katherine E. Rogers, Okhil K. Nag, Michael H. Stewart, Kimihiro Susumu, Eunkeu Oh, James B. Delehanty
-
γ-Functional Iminiumthiolactones for the Single and Double Modification of Peptides Bioconjugate Chem. (IF 4.7) Pub Date : 2023-11-23 Stefan Mommer, Nina Warner, Caroline Lienert
-
mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide–PMO Conjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2023-11-22 Anna-Lina Lessl, Jana Pöhmerer, Yi Lin, Ulrich Wilk, Miriam Höhn, Elisa Hörterer, Ernst Wagner, Ulrich Lächelt
-
Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody–Drug Conjugates Bioconjugate Chem. (IF 4.7) Pub Date : 2023-11-20 Xiaoli Liao, Anthony Haight, Dennie Welch, Linjie Han
-
Exploring Rigid and Flexible Scaffolds to Develop Potent Glucuronic Acid Glycodendrimers for Dengue Virus Inhibition Bioconjugate Chem. (IF 4.7) Pub Date : 2023-11-15 Alejandro Merchán, Pedro Ramírez-López, Carlos Martínez, José Ramón Suárez, Almudena Perona, María J. Hernáiz