Biodiesel fuel has some disadvantages including increase in NOx, poor atomization and incomplete combustion. Additives and catalysts can be used to reduce the negative effects of biodiesel fuel. In addition, the use of metal oxide and metal nanoparticles causes environmental hazards. However, using biodegradable nanoparticles can significantly reduce such concerns. The present study investigated the

Engineered nanomaterials (ENMs) are intentionally designed and produced by humans to revolutionize the manufacturing sector, such as electronic goods, paints, tires, clothes, cosmetic products, and biomedicine. With the spread of these ENMs in our daily lives, scientific research have generated a huge amount of data related to their potential impacts on human and environment health. To date, these

Direct contact with multi-walled carbon nanotubes (MWCNTs) could compromise the viability of macrophages, but the mechanisms remained poorly understood. Previously we investigated the cytotoxicity of MWCNTs with different diameters (XFM4 < XFM22 < XFM34), and showed that MWCNTs induced cytotoxicity in an order of XFM4 > XFM22 > XFM34. In this study, we analyzed the transcriptomic data and found that

Cellulose nanocrystals (CNC) (0.75 or 1.5% w/w) in either a fasting food model (FFM) or a standardized food model (SFM) based on the average USA diet, were digested using a three-phase (oral-gastric-small intestinal) digestion simulator, and the resulting small intestinal phase digestas were applied to an in vitro triculture human cellular model of the small intestinal epithelium (SIE). Effects of

The increased use of polymer nanocomposites in different applications could lead to potential nanofiller release into different human and environmental compartments and consequently, increase the exposure of human and environmental species to nanomaterials. This study aims at determining how the inclusion of nanofillers with diverse chemical nature (SiO2, TiO2, ZnO, multiwalled carbon nanotubes and

Exosomes, a class of small bilayer vesicles derived from virtually all eukaryotic cells, have been exploited as a promising natural delivery platform due to their low toxicity, excellent structural stability, nanoscale size, cargo loading ability, and editable surface structure. To load therapeutic or diagnostic cargos (drugs, nucleic acids, proteins, peptides, and nanomaterials) into exosomes, multiple

In this study, we investigate whether the influence of natural organic matter (NOM) on the aquatic ecotoxicity of engineered nanoparticles (ENPs) can be described quantitatively for the purpose of risk assessments based on existing ecotoxicity studies. A review of the literature studying the aquatic ecotoxicity of ENPs in the presence of NOM identified 66 studies in total, covering the metal and metal

Liver is the major organ in the metabolization of drugs, and detoxification of exogenous substances, including nanoparticles. In clinical medical practice, drug-induced liver injury (DILI) is the major cause of acute liver failure (ALF). In this study, we explore the possible impact of intravenously injected citrate acid (CA), chitosan (CS) and polyethyleneglycol (PEG) functionalized gold nanoparticles

The occurrence of nanoplastics in the environment is now known and presents new threats linked to plastic debris issues. New questions about the formation pathways and life cycle assessment of nanoplastics in continental and marine environments have been raised. In the present study, we focused on the Guadeloupe island coastal system. For the first time, we demonstrated the presence of nanoplastics

The challenge in ensuring the safety of manufactured nanomaterials and products stems from the lack of knowledge among industries about the potential environment and health risks of nanotechnology based innovations and the legislations that apply to them. A lack of information and preparedness for the regulatory safety assessment of innovative nanomaterials and products often lead to their delay in

Cancer, as a global health issue, its treatment with conventional approaches is challenged by non-specific biodistribution and targeting, poor solubility, low therapeutic indices and majorly the development of multi-drug resistance (MDR) that enables the cancer cells to survive against antineoplastic agents. A better understanding in tumor biology as well as a huge progression in nanotechnology in

Preferential Ag deposition in female kidneys has been reported in subacute and subchronic oral gavage and inhalation studies of various sizes of silver nanoparticles (AgNPs). In these in vivo animal studies, female kidneys were shown to accumulate 3–4 times more silver than male kidneys. The current 28-day oral gavage study of AgNPs administered to ovariectomized female rats investigated the effect

The microRNA molecule mir-354 was required for the control of nanopolystyrene toxicity in nematode Caenorhabditis elegans. Exposure to nanopolystyren (100 nm) increased the mir-354 expression; however, the underlying mechanism for this role remains largely unknown. We here further determined the molecular basis of mir-354 in regulating the response to nanopolystyrene. Tissue-specific activity analysis

Alzheimer's disease (AD) is a chronic neurodegenerative disorder associated with dementia. To overcome the limitations of diagnosis and treatment nanotechnology research is bringing more needed and optimum clinical results. The use of nanocarriers for delivering bio-actives to treat neurodegenerative diseases has shown many benefits over common therapies such as the possibility of loading various payloads

Copper(II) oxide nanoparticles (n-CuO) and copper(II) sulfate (CuSO4), commonly used in industrial and agricultural applications, are released in substantial amounts to the environment where they may then interact in unexpected ways with other materials such as engineered nanomaterials (ENM). In this study, we assessed the combined effects of their interaction with titanium(IV) dioxide nanoparticles

The increasing use of Quantum Dots (QDs) - nanoparticles exhibiting unique optical properties – and their incorporation in multiple engineering products is likely to result in the release of this new class of contaminants into natural systems. In soils, bacterial biofilms and mineral surfaces form highly reactive interfaces, which may control QDs' environmental fate. However, little is known regarding

Several engineered nanomaterials (ENMs) are used in toner-based printing equipment (TPE) including laser printers and photocopiers to improve toner performance. High concentration of airborne nanoparticles due to TPE emissions has been documented in copy centers and chamber studies. Recent animal inhalation studies by our group suggested exposure to laser printer-emitted nanoparticles (PEPs) increased

Safe-by-design is an essential component for creating awareness of the potential novel risks associated with the introduction of sophisticated nanomaterials (NMs) with novel properties. SbD is also a useful tool for meeting EU policy ambitions such as the European Green Deal which includes circular economy and moving towards a zero pollution (pollution-free) environment. Unidentified risks are a growing

With the rapid global spread of the new coronavirus and risk of pneumonia from COVID-19 infection, wearing a mask has become an essential defense for all frontline doctors, nurses, and healthcare professionals. Plus, the rise in demand for masks from the general public means the worldwide supply of masks is insufficient, which has led to an increase in the reuse of disposable masks. Therefore, this

Titanium dioxide is widely used as a food additive (E 171), 36% of its composition is nanoparticles. Existing studies have found oral toxic effects of titanium dioxide nanoparticles (TiO2 NPs) on several organs and systems in vivo. Thus, TiO2 NPs may affect the whole body through the internal circulation system. To explore the adverse effect on serum after subchronic exposure to TiO2 NPs, we examined

Precise prediction of airborne carbon nanotube (CNT) filtration and deposition in the lung is of significant importance to find proper control media and to perform exposure assessment to quantify the toxicity for emitted airborne CNTs. We executed a systematic study in order to evaluate the inhalation exposure of inhaled single standing airborne multi-walled carbon nanotubes (MWCNTs) and CNT agglomerates

Silver nanoparticles (AgNPs) are known to enter the aquatic environment via leachates from landfills or by the effluent or sludge of sewage treatment plants. Even if the AgNPs are sulfidized, Ag from these particles was shown to still be available to several species like the benthic freshwater amphipod Hyalella azteca. However, it is still unknown if the primary uptake of Ag from these particles occurs

Due to their increased production and commercial applications, capped silver nanoparticles (AgNPs) have inevitably found their way into aquatic ecosystems. The mobility (fate/transport), bioavailability, reactivity, and toxicity of capped AgNPs are highly influenced by their colloidal stability. This study investigated the aggregation kinetics and interfacial interactions of tannic acid (TA)-coated