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Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes J. Antibiot. (IF 3.3) Pub Date : 2024-03-15 Yuta Kikuchi, Mariko Yoshida, Asaomi Kuwae, Yukihiro Asami, Yuki Inahashi, Akio Abe
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Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits J. Antibiot. (IF 3.3) Pub Date : 2024-03-15 Mark V. Savitskii, Natalia E. Moskaleva, Alex Brito, Pavel A. Markin, Nailya A. Zigangirova, Anna V. Soloveva, Anna B. Sheremet, Natalia E. Bondareva, Nadezhda L. Lubenec, Franco Tagliaro, Vadim V. Tarasov, Kristina A. Tatzhikova, Svetlana A. Appolonova
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Efflux pump inhibitor, phenylalanine-arginine beta-naphthylamide analog potentiates the activity of 5-O-mycaminosyltylonolide for multi-drug resistant Pseudomonas aeruginosa J. Antibiot. (IF 3.3) Pub Date : 2024-03-11 Aoi Kimishima, Masako Honsho, Junsei Terai, Paul Wasuwanich, Sota Honma, Hidehito Matsui, Hideaki Hanaki, Yukihiro Asami
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New antimalarial iromycin analogs produced by Streptomyces sp. RBL-0292 J. Antibiot. (IF 3.3) Pub Date : 2024-03-04 So-ichiro Kimura, Yoshihiro Watanabe, Shiori Shibasaki, Naoya Shinzato, Yuki Inahashi, Toshiaki Sunazuka, Rei Hokari, Aki Ishiyama, Masato Iwatsuki
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Biofilm formation and antimicrobial resistance pattern of uropathogenic E. coli ST131 isolated from children with malignant tumors J. Antibiot. (IF 3.3) Pub Date : 2024-03-04 Noha Anwar Hassuna, Eman M. Rabea, W. K. M. Mahdi, Wedad M. Abdelraheem
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In vitro and ex vivo activity of the fluoroquinolone DC-159a against mycobacteria J. Antibiot. (IF 3.3) Pub Date : 2024-03-04 Belén R. Imperiale, María B. Mancino, Roberto D. Moyano, Silvia de la Barrera, Nora S. Morcillo
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Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds J. Antibiot. (IF 3.3) Pub Date : 2024-03-04 Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Kazuo Shin-ya
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Proansamycin B derivatives from the post-PKS modification gene deletion mutant of Amycolatopsis mediterranei S699 J. Antibiot. (IF 3.3) Pub Date : 2024-02-26 Xinyu Ma, Feng Ye, Xiaochun Zhang, Zhan Li, Yanjiao Ding, Chunhua Lu, Yuemao Shen
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Actinobacterial chalkophores: the biosynthesis of hazimycins J. Antibiot. (IF 3.3) Pub Date : 2024-02-20 Kenichi Matsuda, Hiroto Maruyama, Kumiko Imachi, Haruo Ikeda, Toshiyuki Wakimoto
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Virgaricins C and D, new pramanicin analogs produced by Apiospora sp. FKI-8058 J. Antibiot. (IF 3.3) Pub Date : 2024-02-02 So-ichiro Kimura, Yoshihiro Watanabe, Yudai Mikasa, Rei Miyano, Toshiyuki Tokiwa, Kenichi Nonaka, Takuji Nakashima, Yoshihiko Noguchi, Tomoyasu Hirose, Toshiaki Sunazuka, Rei Hokari, Aki Ishiyama, Masato Iwatsuki
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Antibacterial p-terphenyl and α‑pyrone derivates isolated from the marine-derived actinomycete Nocardiopsis sp. HDN154086 J. Antibiot. (IF 3.3) Pub Date : 2024-01-25 Luning Zhou, Yimin Chang, Shengkuan Yang, Xiaofei Huang, Jiaxiang Wang, Chengyu Jiang, Tianjiao Zhu, Dehai Li, Qian Che
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Synthesis and biological evaluation of nectriatide derivatives, potentiators of amphotericin B activity J. Antibiot. (IF 3.3) Pub Date : 2024-01-24 Kenichiro Nagai, Keisuke Kobayashi, Ryosuke Miyake, Yukino Sato, Reiko Seki, Takashi Fukuda, Akiho Yagi, Ryuji Uchida, Taichi Ohshiro, Hiroshi Tomoda
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Precursor-directed biosynthesis and biological activity of tripropeptin Cpip, a new tripropeptin C analog containing pipecolic acid J. Antibiot. (IF 3.3) Pub Date : 2024-01-24 Hideki Hashizume, Ryuichi Sawa, Yumiko Kubota, Shinya Adachi, Shigeko Harada, Masayuki Igarashi
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Mass spectrometry-guided isolation of thiodiketopiperazines from an EtOAc-extract of Setosphaeria rostrata culture medium and their anti-skin aging effects on TNF-α-induced human dermal fibroblasts J. Antibiot. (IF 3.3) Pub Date : 2024-01-19 Haeun Kwon, Hee Woon Ann, Sojung Park, Jaeyoung Kwon, Keunwan Park, Seung Mok Ryu, Yuanqiang Guo, Jae-Jin Kim, Joung Han Yim, Il-Chan Kim, Sang Hee Shim, Sullim Lee, Dongho Lee
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The tunicamycin derivative TunR2 exhibits potent antibiotic properties with low toxicity in an in vivo Mycobacterium marinum-zebrafish TB infection model J. Antibiot. (IF 3.3) Pub Date : 2024-01-18 Hannah J. T. Nonarath, Michael A. Jackson, Renee M. Penoske, Thomas C. Zahrt, Neil P. J. Price, Brian A. Link
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Design, biological characteristics, and antibacterial mechanism of high therapeutic index antimicrobial peptides with PRRP as central axis J. Antibiot. (IF 3.3) Pub Date : 2024-01-17 Shuang Yu, Boyan Jia, Ying Zhang, Yue Yu, Zhihua Pei, Hongxia Ma
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Semi-synthesis and structure-activity relationship study yield antibacterial vicenistatin derivatives with low cytotoxicity J. Antibiot. (IF 3.3) Pub Date : 2024-01-16 Jun Li, Zhenye Yang, Chuanling Shi, Xiaoyun Wu, Le Zhou, Yongqian Liang, Qinglian Li, Jianhua Ju
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Identification of a new oligomycin derivative as a specific inhibitor of the alternative peptidoglycan biosynthetic pathway J. Antibiot. (IF 3.3) Pub Date : 2024-01-10 Shuhei Umetsu, Takeshi Tsunoda, Haruka Kiyanagi, Yuki Inahashi, Kenichi Nonaka, Tohru Dairi, Yasushi Ogasawara
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Antifungal profile against Candida auris clinical isolates of tyroscherin and its new analog produced by the deep-sea-derived fungal strain Scedosporium apiospermum FKJ-0499 J. Antibiot. (IF 3.3) Pub Date : 2024-01-11 Haruki Azami, Yoshihiro Watanabe, Kazunari Sakai, Hiroki Nakahara, Hiroki Kojima, Toshiyuki Tokiwa, Kenichi Nonaka, Yoshihiko Noguchi, Yuriko Nagano, Tomoyasu Hirose, Toshiaki Sunazuka, Hidehito Matsui, Naoaki Arima, Kazutoyo Abe, Hideaki Hanaki, Masato Iwatsuki
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Precezomycin, a novel antibiotic biosynthetic precursor of cezomycin, from actinomycete Kitasatospora putterlickiae 10–13 J. Antibiot. (IF 3.3) Pub Date : 2024-01-10 Di Mao, Pengwei Yu, Naoya Shinzato, Lei Zhang, Weiping Zheng, Shan Lu, Hideaki Kakeya
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The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus J. Antibiot. (IF 3.3) Pub Date : 2024-01-04 Masako Honsho, Aoi Kimishima, Akari Ikeda, Masato Iwatsuki, Kenichi Nonaka, Hidehito Matsui, Hideaki Hanaki, Yukihiro Asami, Toshiaki Sunazuka
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Micrococcus lacusdianchii sp. nov., an attached bacterium inhibited by metabolites from its symbiotic algae J. Antibiot. (IF 3.3) Pub Date : 2023-12-26 Le Wang, Yao Xiao, Wenxin Lai, Ru Jia, Qinglin Deng, Xin Wang, Hongqiu Shi, Yiwen Yang, Binghuo Zhang
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Discovery of antifungal secondary metabolites from an intestinal fungus Fusarium sp. J. Antibiot. (IF 3.3) Pub Date : 2023-12-26 Mingkai Zhang, Baosong Chen, Huanqin Dai, Jingzu Sun, Hongwei Liu, Junjie Han
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Cephalosporin resistance, tolerance, and approaches to improve their activities J. Antibiot. (IF 3.3) Pub Date : 2023-12-19 Alison H. Araten, Rachel S. Brooks, Sarah D. W. Choi, Laura L. Esguerra, Diana Savchyn, Emily J. Wu, Gabrielle Leon, Katherine J. Sniezek, Mark P. Brynildsen
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Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594 J. Antibiot. (IF 3.3) Pub Date : 2023-12-18 Alastair E. Lacey, Scott A. Minns, Rachel Chen, Daniel Vuong, Ernest Lacey, John A. Kalaitzis, Yu Pei Tan, Roger G. Shivas, Mark S. Butler, Andrew M. Piggott
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TNF-α-induced down-regulation of type I interferon receptor contributes to acquired resistance of cervical squamous cancer to Cisplatin J. Antibiot. (IF 3.3) Pub Date : 2023-12-15 Yani Yu, Jia Yu, Xiaorong Cui, Xin Sun, Xiaohui Yu
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Antimicrobial resistance rates of urogenital Mycoplasma hominis and Ureaplasma species before and during the COVID-19 pandemic: results from a Greek survey, 2014 to 2022 J. Antibiot. (IF 3.3) Pub Date : 2023-11-29 Karolina Akinosoglou, Aristotelis Tsiakalos, Ioanna D. Dimopoulou, Georgios Schinas, Eleni Polyzou, Jenny Kourea-Kremastinou, Vassiliki C. Pitiriga
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Remembering Dr. Shinichi Kondo (15 June 1928-8 October 2022). J. Antibiot. (IF 3.3) Pub Date : 2023-11-30 Keiichi Ajito
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Anti-microbial efficacy of l-glutaminase (EC 3.5.1.2) against multidrug-resistant Pseudomonas aeruginosa infection J. Antibiot. (IF 3.3) Pub Date : 2023-11-28 Likaa H. Mahdi, Buthenia A. Hasoon, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Kareem H. Jawad, Ali G. Al-Dulimi, Rajwa H. Essa, Salim Albukhaty, Riaz Khan
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Catenulopyrizomicins, new anti-Hepatitis B virus compounds, from the rare actinomycete Catenuloplanes sp. MM782L-181F7 J. Antibiot. (IF 3.3) Pub Date : 2023-11-27 Manabu Yamasaki, Ryuichi Sawa, Hideyuki Muramatsu, Yui Yamamoto, Maya Umekita, Yumiko Kubota, Yumi Kanegae, Masayuki Igarashi
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Two new adenopeptins B and C inhibit sphere formation of pancreatic cancer cells J. Antibiot. (IF 3.3) Pub Date : 2023-11-24 Daisuke Tatsuda, Masahide Amemiya, Chisato Nosaka, Ryuichi Sawa, Hideyuki Muramatsu, Masayuki Igarashi, Junjiro Yoshida, Tomokazu Ohishi, Manabu Kawada
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Evaluation of A-ring hydroxymethylene-amino- triterpenoids as inhibitors of SARS-CoV-2 spike pseudovirus and influenza H1N1 J. Antibiot. (IF 3.3) Pub Date : 2023-11-24 Oxana Kazakova, Xinyuan Ma, Elena Tretyakova, Irina Smirnova, Alexander Slita, Ekaterina Sinegubova, Vladimir Zarubaev, Hongwei Jin, Demin Zhou, Sulong Xiao
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Chromatin-modifying protein 4C (CHMP4C) affects breast cancer cell growth and doxorubicin resistance as a potential breast cancer therapeutic target J. Antibiot. (IF 3.3) Pub Date : 2023-11-22 Xiaoyan Jin, Jian Wang, Zhengyi Wang, Wenyang Pang, Yong Chen, Li Yang
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Bioactive ambuic acid congeners from endophytic fungus Pestalotiopsis trachicarpicola SC-J551 J. Antibiot. (IF 3.3) Pub Date : 2023-11-13 Fanyu Dong, Zhiming Jiang, Ping Wu, Fangfang Duan, Jinghua Xue, Haibo Tan, Xiaoyi Wei
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Identification of siderophores blocking infection of Pseudomonas aeruginosa from Kitasatospora sp. LS1784 J. Antibiot. (IF 3.3) Pub Date : 2023-11-10 Baosong Chen, Yue Wang, Feng Xie, Hongwei Liu, Huanqin Dai
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Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation J. Antibiot. (IF 3.3) Pub Date : 2023-11-08 Shiina Suzuki, Shun Saito, Yuki Narushima, Shunta Kodani, Noritaka Kagaya, Hikaru Suenaga, Kazuo Shin-ya, Midori A. Arai
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Antiviral potency of lupane and oleanane alkynyl-derivatives against human cytomegalovirus and papillomavirus J. Antibiot. (IF 3.3) Pub Date : 2023-11-07 Elmira F. Khusnutdinova, Anastasiya V. Petrova, Oxana B. Kazakova
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Amoxetamide A, a new anoikis inducer, produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis J. Antibiot. (IF 3.3) Pub Date : 2023-10-30 Chengqian Pan, Hiroaki Ikeda, Mayuri Minote, Tensei Tokuda, Takefumi Kuranaga, Tohru Taniguchi, Naoya Shinzato, Hiroyasu Onaka, Hideaki Kakeya
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A new steroid with potent antimicrobial activities and two new polyketides from Penicillium variabile EN-394, a fungus obtained from the marine red alga Rhodomela confervoides J. Antibiot. (IF 3.3) Pub Date : 2023-10-26 Fan-Zhong Zhang, Xiao-Ming Li, Ling-Hong Meng, Bin-Gui Wang
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Potent Rifampicin derivatives can clear MRSA infections at single low doses when concomitantly dosed with Vancomycin J. Antibiot. (IF 3.3) Pub Date : 2023-10-23 Thomas Nittoli, Anna Brotcke Zumsteg, Abira Bandyopadhyay, Stephanie Federici, Alida Coppi, Susan Jorgenson, Seung-Yong Choi, Mrinmoy Saha, Benjamin Wertz, Priyanka Trivedi, Chandrashekhar Korgaonkar, Harvey Chin, Onson Luong, Christos Kyratsous, William Olson
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Eleuthemarins A and B, two new isocoumarin derivatives from the Arctic fungus Eleutheromyces sp. CPCC 401592 J. Antibiot. (IF 3.3) Pub Date : 2023-10-19 Yan Tang, Jun Hu, Zhe Guo, Jinglin Bai, Qingrong Du, Tao Zhang, Shengjun Dai, Liyan Yu, Dewu Zhang
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Antimicrobial polyketides from Magellan Seamount-derived fungus Talaromyces scorteus AS-242 J. Antibiot. (IF 3.3) Pub Date : 2023-10-17 Ying Wang, Zhen Ying, Xiao-Ming Li, Sui-Qun Yang, Hong-Lei Li, Bin-Gui Wang, Ling-Hong Meng
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Formanilides from the culture broth of Perenniporia fraxinea J. Antibiot. (IF 3.3) Pub Date : 2023-10-16 Dae-Cheol Choi, Dae-Won Ki, Young-Hee Kim, In-Kyoung Lee, Bong-Sik Yun
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Unveiling synergism of polymyxin B with chloramphenicol derivatives against multidrug-resistant (MDR) Klebsiella pneumoniae J. Antibiot. (IF 3.3) Pub Date : 2023-10-11 Nurulain Idris, Kok Hoong Leong, Eng Hwa Wong, Nusaibah Abdul Rahim
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Rv1255c, a dormancy-related transcriptional regulator of TetR family in Mycobacterium tuberculosis, enhances isoniazid tolerance in Mycobacterium smegmatis J. Antibiot. (IF 3.3) Pub Date : 2023-10-11 Jijimole Gopi Reji, Lakshmi K. Edison, Sajith Raghunandanan, Akhil Raj Pushparajan, Krishna Kurthkoti, Ramakrsihnan Ajay Kumar
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Two new diketopiperazines from the Cordyceps fungus Samsoniella sp. XY4 J. Antibiot. (IF 3.3) Pub Date : 2023-10-03 Ke-Tao Zhang, Zhi-Pu Huang, Xiao-Rong Xu, Si-Heng Li, Yu-Xiao Xu, Qing Zhao, Xiao-Mei Zhang
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Cycloimidamicins, Novel natural lead compounds for translation inhibition in Pseudomonas aeruginosa J. Antibiot. (IF 3.3) Pub Date : 2023-09-27 Yoshimasa Ishizaki, Maya Umekita, Rie Arisaka, Masaki Hatano, Tomoyuki Kimura, Yumiko Kubota, Yuko Shibuya, Chigusa Hayashi, Ryuichi Sawa, Masayuki Igarashi
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A novel aromatic compound from the fungus Synnemellisia sp. FKR-0921 J. Antibiot. (IF 3.3) Pub Date : 2023-09-27 Arisu Tahara, Kazuki Tani, Miyu Wakatsuki, Toshiyuki Tokiwa, Mayuka Higo, Kenichi Nonaka, Tomoyasu Hirose, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Yoshihiro Watanabe, Masako Honsho, Yukihiro Asami, Hidehito Matsui, Toshiaki Sunazuka, Hideaki Hanaki, Toshiaki Teruya, Takahiro Ishii
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When less is more: shortening the Lpp protein leads to increased vancomycin resistance in Escherichia coli J. Antibiot. (IF 3.3) Pub Date : 2023-09-25 Hannah Wykes, Vuong Van Hung Le, Catrina Olivera, Jasna Rakonjac
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Pullusurfactins A‒C, new biosurfactants produced by Aureobasidium pullulans A11231-1-58 from Chrysanthemum boreale Makino J. Antibiot. (IF 3.3) Pub Date : 2023-09-25 Jong-Shik Kim, Dae-Won Ki, In-Kyoung Lee, Bong-Sik Yun
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Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae J. Antibiot. (IF 3.3) Pub Date : 2023-09-20 Robert A. Shepherd, Cody E. Earp, Kristof B. Cank, Huzefa A. Raja, Joanna Burdette, Steven P. Maher, Adriana A. Marin, Anthony A. Ruberto, Sarah Lee Mai, Blaise A. Darveaux, Dennis E. Kyle, Cedric J. Pearce, Nicholas H. Oberlies
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Haneummycin, a new 22-membered macrolide lactam antibiotic, produced by marine-derived Streptomyces sp. KM77-8 J. Antibiot. (IF 3.3) Pub Date : 2023-09-19 Moeka Uemura, Keisuke Kobayashi, Noriko Sato, Kenichiro Nagai, Reiko Seki, Michiya Kamio, Takashi Fukuda, Taishi Tsubouchi, Hiroshi Tomoda, Taichi Ohshiro, Takeshi Kobayashi, Takeshi Terahara
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Botryorhodines K and L, two new cytotoxic depsidones from a fungus of the genus Arcopilus J. Antibiot. (IF 3.3) Pub Date : 2023-09-05 Zhiwei Zhang, Yiwei Ge, Yasuko In, Yasuhiro Igarashi
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Aspects for development of novel antibacterial medicines using a vitamin D3 decomposition product in Helicobacter pylori infection J. Antibiot. (IF 3.3) Pub Date : 2023-09-01 Kiyofumi Wanibuchi, Kouichi Hosoda, Avarzed Amgalanbaatar, Masato Ihara, Motoki Takezawa, Yuki Sakai, Hisashi Masui, Mitsuru Shoji, Shunji Hayashi, Hirofumi Shimomura
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Antibiotic stewardship programs should include disinfectants and biocides. J. Antibiot. (IF 3.3) Pub Date : 2023-08-31 Prabhavathi Fernandes
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In vitro activity of cefiderocol in combination with new β-lactam/β-lactamase inhibitor combinations (βL-βLICs) against multidrug resistant KPC-producing Klebsiella pneumoniae J. Antibiot. (IF 3.3) Pub Date : 2023-08-30 Paolo Gaibani, Tiziana Lazzarotto, PierLuigi Viale, Simone Ambretti
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(±) Pestalactone D and pestapyrone F, two new isocoumarins from an endolichenic Pestalotiopsis rhododendri J. Antibiot. (IF 3.3) Pub Date : 2023-08-24 Mengyuan Wang, Mengna Luo, Xiaotian Ding, Shanshan Chang, Ning He, Bin Hong, Yunying Xie
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Mechanisms of emerging resistance associated with non-antibiotic antimicrobial agents: a state-of-the-art review J. Antibiot. (IF 3.3) Pub Date : 2023-08-21 Mirza Ilyas Rahim Baig, Pramod Kadu, Pradip Bawane, Kartik T. Nakhate, Santosh Yele, Shreesh Ojha, Sameer N. Goyal
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Saccharopolyspora oryzae sp. nov., isolated from rhizosphere soil of the wild rice species Oryza rufipogon J. Antibiot. (IF 3.3) Pub Date : 2023-08-18 Sirikarn Kammanee, Supattra Muangham, Waranya Butdee, Chollachai Klaysubun, Yasuhiro Igarashi, Kannika Duangmal