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Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-14 Adriana Knezic, Elena Budusan, Natalie J. Saez, Brad R. S. Broughton, Lachlan D. Rash, Glenn F. King, Robert E. Widdop, Claudia A. McCarthy
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Recommended Tool Compounds for Modifying the Cystic Fibrosis Transmembrane Conductance Regulator Channel Variants ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-14 XiaoXuan Han, Danni Li, Yimin Zhu, Elena K. Schneider-Futschik
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Immunoactivation by Cutaneous Blue Light Irradiation Inhibits Remote Tumor Growth and Metastasis ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-16 Yingchun Yang, Rong Yang, Fangqing Deng, Luqiu Yang, Guanghao Yang, Yanyan Liu, Qing Tian, Zixi Wang, Aipeng Li, Li Shang, Genyang Cheng, Lianbing Zhang
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Migraine and Its Treatment from the Medicinal Chemistry Perspective ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-16 Ezgi Pehlivanlar, Simone Carradori, Rahime Simsek
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Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-14 Bochuan Deng, Jiao Zhang, Xiang Zhang, Dan Wang, Lu Cheng, Ping Su, Tingli Yu, Guangjun Bao, Guofeng Li, Liang Hong, Xiaokang Miao, Wenle Yang, Rui Wang, Junqiu Xie
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Protein Corona Composition of Gold Nanocatalysts ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-14 Ali Akbar Ashkarran, Soheyl Tadjiki, Zijin Lin, Kylie Hilsen, Noor Ghazali, Sarah Krikor, Shahriar Sharifi, Meisam Asgari, Michael Hotchkin, Adam Dorfman, Karen S. Ho, Morteza Mahmoudi
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Digital Futures of Learning Pharmacology and Medicinal and Organic Chemistry ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-14 Fun Man Fung, Etienne Blanc, Xavier Coumoul
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Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-12 Shumei Wang, Kang Lei, Hsien-Tsung Lai, Tingting Liu, Lupei Du, Shwu-Yuan Wu, Xiaohan Ye, Cheng-Ming Chiang, Minyong Li
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Updates on Overcoming Bicalutamide Resistance: A Glimpse into Resistance to a Novel Antiandrogen ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-07 Mehrnaz Izady, Fatemeh Khatami, Zeinab Ahadi, Hassan Roudgari, Seyed Mohammad Kazem Aghamir
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Correction to “Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity” ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-06 Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A. Laufer, Christa E. Müller, Michael Gütschow, Thanigaimalai Pillaiyar
The affiliation for author Matthias Olfert is to be changed. The correct affiliation for where Mr. Olfert was when the work was done for the originally published paper is: Institute of Pharmacy, Pharmaceutical (Bio-)Analysis, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany. The changes are reflected in the authorship and Supporting Information of this Correction
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Photodynamic Therapy of LD4-Photosensitizer Attenuates the Acute Pneumonia Induced by Klebsiella pneumoniae ACS Pharmacol. Transl. Sci. Pub Date : 2024-03-05 Zhuo Tao, Xin Li, Hongzhi Yu, Junping Wu, Ying Wen, Tianjun Liu
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Correction to “Digoxin-Mediated Inhibition of Potential Hypoxia-Related Angiogenic Repair in Modulated Electro-Hyperthermia (mEHT)-Treated Murine Triple-Negative Breast Cancer Model” ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-28 Syeda Mahak Zahra Bokhari, Kenan Aloss, Pedro Henrique Leroy Viana, Csaba András Schvarcz, Balázs Besztercei, Nino Giunashvili, Dániel Bócsi, Zoltán Koós, Andrea Balogh, Zoltán Benyó, Péter Hamar
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Modulation of Abundance and Location of High-Mobility Group Box 1 in Human Microglia and Macrophages under Oxygen–Glucose Deprivation ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-27 Patrick-Brian Bielawski, Issan Zhang, Clara Correa-Paz, Francisco Campos, Martina Migliavacca, Ester Polo, Pablo Del Pino, Beatriz Pelaz, Denis Vivien, Dusica Maysinger
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Calcitonin Inhibits Phenotypic Switching of Aortic Smooth Muscle Cells and Neointimal Hyperplasia through the AMP-Activated Protein Kinase/Mechanistic Target of Rapamycin Pathway ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-23 Mingyu Liu, Fei Xiang, Tao Yang, Yujia Sun, Jiemei Yang, Tengyu Wang, Sixuan Chen, Yingjie Xu, Gaojun Shan, Yuanqi Shi, Zengxiang Dong, Yuanyuan Guo
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Schisandrin B Suppresses Colon Cancer Growth by Inducing Cell Cycle Arrest and Apoptosis: Molecular Mechanism and Therapeutic Potential ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-22 Vanessa Anna Co, Hani El-Nezami, Yawen Liu, Bonsra Twum, Priyanka Dey, Paul A. Cox, Shalu Joseph, Roland Agbodjan-Dossou, Mehdi Sabzichi, Roger Draheim, Murphy Lam Yim Wan
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Toward Translational Impact of Low-Glucose Strategies on Red Blood Cell Storage Optimization ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-22 Logan D. Soule, Lauren Skrajewski-Schuler, Stephen A. Branch, Timothy J. McMahon, Dana M. Spence
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Emerging Landscape of Supercharged Proteins and Peptides for Drug Delivery ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-21 Lidan Wang, Jingping Geng, Hu Wang
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2-(Difluoromethyl)-1,3,4-oxadiazoles: The Future of Selective Histone Deacetylase 6 Modulation? ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-20 Beate König, Finn K. Hansen
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Effects of Itraconazole on Pharmacokinetics of Mitragynine and 7-Hydroxymitragynine in Healthy Volunteers ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-20 Pooja Mongar, Amit Jaisi, Thammasin Inkviya, Juraithip Wungsintaweekul, Kamonthip Wiwattanawongsa
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Santacruzamate A Alleviates Pain and Pain-Related Adverse Emotions through the Inhibition of Microglial Activation in the Anterior Cingulate Cortex ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-16 Yan Qin, Qingqing Liu, Saiying Wang, Qinhui Wang, Yaya Du, Jingyue Yao, Yue Chen, Qi Yang, Yumei Wu, Shuibing Liu, Minggao Zhao, Gaofei Wei, Le Yang
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Evolutionary Identification of the Requirement of the Second Intracellular Loop for the Constitutive Activity of Melanocortin-4 Receptors ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-15 Bingxin Xu, Jindong Yao, Wenqi Song, Xinyi Yan, Ming Zhu, Jiangtao Li, Zhonglin Ma, Yanchuan Li, Yihao Li, Yanbin Fu, Liu Liu, Lei Li, Jianjun Lyu, Chao Zhang
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Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-15 Yves Haufe, Dominik Loser, Timm Danker, Annette Nicke
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Linderane Attenuates Complete Freund’s Adjuvant-Induced Pain and Anxiety in Mice by Restoring Anterior Cingulate Cortex Microglia M2 Polarization through Activating Cannabinoid 2 Receptor ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-15 Yue Chen, Yan Qin, Ying Gao, Saiying Wang, Qinhui Wang, Xiuling Tang, Zheng Rong, Caiyan Cheng, Longfei Li, Yuan Xu, Qi Yang, Yuping Tang, Minggao Zhao, Le Yang
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Biomarkers for Early Cancer Detection: A Landscape View of Recent Advancements, Spotlighting Pancreatic and Liver Cancers ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-14 Rumiana Tenchov, Aparna K. Sapra, Janet Sasso, Krittika Ralhan, Anusha Tummala, Norman Azoulay, Qiongqiong Angela Zhou
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Call for Papers: New Perspectives and Advances in Translational Pain Research ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-14 Daniela Salvemini, Aubin Moutal
This article has not yet been cited by other publications.
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Third-Generation Solid Dispersion Through Lyophilization Enhanced Oral Bioavailability of Resveratrol ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-14 Hugo Almeida, Bárbara Ferreira, Carlos Fernandes-Lopes, Francisca Araújo, Maria João Bonifácio, Teófilo Vasconcelos, Bruno Sarmento
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Structure-Based Identification of Kelch-like ECH-Associated Protein 1 as a Pharmacological Target of Electrophile-Containing Catechol-O-Methyltransferase Inhibitors ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-13 Ping Wang, Yang Li, Jinyi Yang, Ziwen Li, Xintong Ren, Qingshi Meng, Pengfei Li, Luzhe Qin, Wei Li, Yuting Xie, Nannan Hou, Niu Huang
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Improved Methodology for Evaluating Nanomedicine Antibacterial Properties in Biological Fluids ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-13 Ali Akbar Ashkarran, Shahriar Sharifi, Christopher N. LaRock, Morteza Mahmoudi
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Characterization of a Nonselective Opioid Receptor Functional Antagonist: Implications for Development as a Novel Opioid Dependence Medication ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-12 Siavash Shahbazi Nia, Yuma T. Ortiz, Julio D. Zuarth Gonzalez, Leila Shamir, Kofi Frimpong-Manson, Mohammad Anwar Hossain, Sadisna Shahi, Rayna Bandy, Anoushka Bhat, Dhavalkumar Patel, Hanin Diab, Jonathan Thompson, Lance R. McMahon, Jenny L. Wilkerson, Nadezhda A. German
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Microbial Features Linked to Medication Strategies in Cardiometabolic Disease Management ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-05 Jane Shearer, Shrushti Shah, Grace Shen-Tu, Kristina Schlicht, Matthias Laudes, Chunlong Mu
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Investigating LIM (Lin-11, Isl-1, and Mec-3) Kinases and Their Correlation with Pathological Events and Microtubule Dynamics in an Experimental Model of Spinal Cord Injury in Rats ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-07 Abhishek Roy, Zarna Pathak, Hemant Kumar
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Chemical Proteomics Reveals that the Anticancer Drug Everolimus Affects the Ubiquitin–Proteasome System ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-07 Anna A. Lobas, Amir Ata Saei, Hezheng Lyu, Roman A. Zubarev, Mikhail V. Gorshkov
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Functional Roles of Furin in Cardio-Cerebrovascular Diseases ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-07 Surasak Wichaiyo, Pimpisid Koonyosying, Noppawan Phumala Morales
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Enhancing RNA Payload and Temperature Stability and Activity with Cationic Peptide-Coated Zinc Oxide Nanoparticles ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-07 Robert K. DeLong, Juliet Nava-Chavez, Rakshith Kumar, Elza Neelima Mathew, Waithaka Mwangi, Sunyoung Yoon
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Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-06 Hevna Dhulkifle, Mohammad Issam Diab, Majed Algonaiah, Hesham M. Korashy, Zaid H. Maayah
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Activation of Multiple G Protein Pathways to Characterize the Five Dopamine Receptor Subtypes Using Bioluminescence Technology ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-06 Denise Mönnich, Laura J. Humphrys, Carina Höring, Bradley L. Hoare, Lisa Forster, Steffen Pockes
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Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-05 Grant C. Glatfelter, Eline Pottie, John S. Partilla, Christophe P. Stove, Michael H. Baumann
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Phage Display Identified Novel Leydig Cell Homing Peptides for Testicular Targeting ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-05 Yugandhara Jirwankar, Akanksha Nair, Soumitra Marathe, Vikas Dighe
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Cytochrome P450 Family 4F2 and 4F11 Haplotype Mapping and Association with Hepatic Gene Expression and Vitamin K Hydroxylation Activity ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-03 Ayoade N. Alade, Katrina G. Claw, Matthew G. McDonald, Bhagwat Prasad, Allan E. Rettie, Kenneth E. Thummel
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Inversion of the Warburg Effect: Unraveling the Metabolic Nexus between Obesity and Cancer ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-02 Reshmi Akter, Muhammad Awais, Vinothini Boopathi, Jong Chan Ahn, Deok Chun Yang, Se Chan Kang, Dong Uk Yang, Seok-Kyu Jung
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Neutralization of SARS-CoV-2 and Intranasal Protection of Mice with a nanoCLAMP Antibody Mimetic ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-01 Quentin Pagneux, Nathalie Garnier, Manon Fabregue, Sarah Sharkaoui, Sophie Mazzoli, Ilka Engelmann, Rabah Boukherroub, Mary Strecker, Eric Cruz, Peter Ducos, Sabine Szunerits, Ana Zarubica, Richard Suderman
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Rosuvastatin Enhances Lymphangiogenesis after Myocardial Infarction by Regulating the miRNAs/Vascular Endothelial Growth Factor Receptor 3 (miRNAs/VEGFR3) Pathway ACS Pharmacol. Transl. Sci. Pub Date : 2024-02-01 Zheng Lian, Shi-Ran Yu, Yu-Xia Cui, Su-Fang Li, Li−Na Su, Jun-Xian Song, Chong-Yoo Lee, Qi-Xin Chen, Hong Chen
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Serotonin-2 Receptor Agonists Produce Anti-inflammatory Effects through Functionally Selective Mechanisms That Involve the Suppression of Disease-Induced Arginase 1 Expression ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-25 Thomas W. Flanagan, Timothy P. Foster, Thomas E. Galbato, Pek Yee Lum, Brent Louie, Gavin Song, Adam L. Halberstadt, Gerald B. Billac, Charles D. Nichols
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Juglone as a Natural Quorum Sensing Inhibitor against Pseudomonas aeruginosa pqs-Mediated Virulence and Biofilms ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-25 Yeping Ma, Wing Suet Tang, Sylvia Yang Liu, Bee Luan Khoo, Song Lin Chua
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Peptide-Drug Conjugates: Design, Chemistry, and Drug Delivery System as a Novel Cancer Theranostic ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-24 Syed Faheem Askari Rizvi, Linjie Zhang, Haixia Zhang, Quan Fang
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miR-873-5p Suppression Reinvigorates Aging Mesenchymal Stem Cells and Improves Cardiac Repair after Myocardial Infarction ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-23 Wenwu Zhu, Wei Du, Rui Duan, Yan Liu, Bin Zong, Xin Jin, Zishuang Dong, Hui Wang, Siyamak Shahab, Haoran Wang, Yimei Hong, Bing Han
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Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-19 Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A. Laufer, Christa E. Müller, Michael Gütschow, Thanigaimalai Pillaiyar
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2,4′-Dihydroxybenzophenone Exerts Bone Formation and Antiosteoporotic Activity by Stimulating the β-Catenin Signaling Pathway ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-19 Mirissa Hewage Dumindu Kavinda, Mi-Hwa Lee, Chang-Hee Kang, Yung Hyun Choi, Gi-Young Kim
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Effect of Trichinella spiralis-Derived Antigens on Nonalcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-18 Yong Yang, Yanzhao He, Xiaodan Yang, Yuyu Qiao, Gaoqin Yi, Weiping Fan, Hongli Liu, Mingwei Tong
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Model-Informed Dose Selection for a Novel Human Immunoglobulin G4 Derived Monoclonal Antibody Targeting Proprotein Convertase Kwashiorkor Type 9: Insights from Population Pharmacokinetics–Pharmacodynamics and Systems Pharmacology ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-17 Jinfu Peng, Jie Huang, Hongyi Tan, Yun Kuang, Guoping Yang, Zhijun Huang
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Polydopamine-Based Resveratrol-Hyaluronidase Nanomedicine Inhibited Pancreatic Cancer Cell Invasive Phenotype in Hyaluronic Acid Enrichment Tumor Sphere Model ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-15 Shuo Yu, Lu Zhang, Yanshen Yang, Meijuan Wang, Tingting Liu, Wenwen Ji, Yang Liu, Hao Lv, Yang Zhao, Xi Chen, Tinghua Hu
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Methotrexate Inhibits the Binding of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Receptor Binding Domain to the Host-Cell Angiotensin-Converting Enzyme-2 (ACE-2) Receptor ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-16 Soo-Kyung Kim, Sartanee Suebka, Adley Gin, Phuong-Diem Nguyen, Yisha Tang, Judith Su, William A. Goddard III
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3,4-Diarylisoxazoles─Analogues of Combretastatin A-4: Design, Synthesis, and Biological Evaluation In Vitro and In Vivo ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-16 Georgy L. Karetnikov, Lilya A. Vasilyeva, Gulalek Babayeva, Vadim S. Pokrovsky, Dmitry A. Skvortsov, Oksana B. Bondarenko
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Preclinical Investigations on Anti-fibrotic Potential of Long-Term Oral Therapy of Sodium Astragalosidate in Animal Models of Cardiac and Renal Fibrosis ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-12 Xiao-Yi Chen, Tian-Tian Wang, Qing Shen, Hao Ma, Zhan-Hua Li, Xi-Na Yu, Xiao-Feng Huang, Lin-Sen Qing, Pei Luo
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Pharmacology of a Plant Virus Immunotherapy Candidate for Peritoneal Metastatic Ovarian Cancer ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-10 Anthony O. Omole, Jessica Fernanda Affonso de Oliveira, Lucas Sutorus, Nicole F. Steinmetz
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Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-09 Alberto Boretti
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Digoxin-Mediated Inhibition of Potential Hypoxia-Related Angiogenic Repair in Modulated Electro-Hyperthermia (mEHT)-Treated Murine Triple-Negative Breast Cancer Model ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-09 Syeda Mahak Zahra Bokhari, Kenan Aloss, Pedro Henrique Leroy Viana, Csaba András Schvarcz, Balázs Besztercei, Nino Giunashvili, Dániel Bócsi, Zoltán Koós, Andrea Balogh, Zoltán Benyó, Péter Hamar
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Systematic Investigation of Dose-Dependent Protein Thermal Stability Changes to Uncover the Mechanisms of the Pleiotropic Effects of Metformin ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-09 Kejun Yin, Ronghu Wu
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Series of (([1,1′-Biphenyl]-2-yl)methyl)sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-05 Therese C. Ku, Jianjing Cao, Sung Joon Won, Jiqing Guo, Gisela A. Camacho-Hernandez, Amarachi V. Okorom, Kristine Walloe Salomon, Kuo Hao Lee, Claus J. Loland, Henry J. Duff, Lei Shi, Amy Hauck Newman
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Development of Noninvasive Activity-Based Protein Profiling-Bioluminescence Resonance Energy Transfer Platform Technology Enables Target Engagement Studies with Absolute Specificity in Living Systems ACS Pharmacol. Transl. Sci. Pub Date : 2024-01-04 Punita Bathla, Aaiyas Mujawar, Abhijit De, Britto S. Sandanaraj