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Enhancing oral bioavailability of an antifungal thiazolylhydrazone derivative: Development and characterization of a self-emulsifying drug delivery system Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-16 Iara Rinco Silva, Mateus Araújo Castro e Souza, Renes Resende Machado, Renata Barbosa de Oliveira, Elaine Amaral Leite, Isabela da Costa César
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Nasal delivery of encapsulated recombinant ACE2 as a prophylactic drug for SARS-CoV-2 Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-16 Alberto Baldelli, Chun Yuen Jerry Wong, Hale Oguzlu, Hanieh Gholizadeh, Yigong Guo, Hui Xin Ong, Anika Singh, Daniela Traini, Anubhav Pratap-Singh
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Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer’s disease Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-16 Jingyu Liu, Jikai Xu, Luan Jia, Yanjun Zhou, Qiang Fu, Yichen Wang, Danyang Mu, Dequan Wang, Ning Li, Yue Hou
Nano-pterostilbene demonstrated improved learning and memory and provided superior neuronal protection compared to pterostilbene.
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UV–VIS imaging-based investigation of API concentration fluctuation caused by the sticking behaviour of pharmaceutical powder blends Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Orsolya Péterfi, Lilla Alexandra Mészáros, Bence Szabó-Szőcs, Máté Ficzere, Emese Sipos, Attila Farkas, Dorián László Galata, Zsombor Kristóf Nagy
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Genesis, mechanism, and avoidance of cosmetic coating defects – An industrial case study Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Karsten Flügel, Raphael Wiedey, Carolin Riehl, Ingo Kaminski, Markus Riehl
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Red blood cell membrane-camouflaged gold-core silica shell nanorods for cancer drug delivery and photothermal therapy Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Carolina F. Rodrigues, Ilídio J. Correia, André F. Moreira
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A special issue dedicated to the 2022 meeting of the French Society for Nanomedicine Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Lucie Sancey, Yohann Corvis, Sylvie Begin-Colin, Nicolas Tsapis
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Customizable orodispersible films: Inkjet printing and data matrix encoding for personalized hydrocortisone dosing Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Lucía Rodríguez-Pombo, Paola Carou-Senra, Erea Rodríguez-Martínez, Patricija Januskaite, Carlos Rial, Paulo Félix, Carmen Alvarez-Lorenzo, Abdul W. Basit, Alvaro Goyanes
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Nanobody-mediated targeting of zinc phthalocyanine with polymer micelles as nanocarriers Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Bárbara Mesquita, Arunika Singh, Cèlia Prats Masdeu, Nienke Lokhorst, Erik R. Hebels, Mies van Steenbergen, Enrico Mastrobattista, Michal Heger, Cornelus F. van Nostrum, Sabrina Oliveira
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Implementation of near-infrared spectroscopy and convolutional neural networks for predicting particle size distribution in fluidized bed granulation Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Cheng Peng, Liang Zhong, Lele Gao, Lian Li, Lei Nie, Aoli Wu, Ruiqi Huang, Weilu Tian, Wenping Yin, Hui Wang, Qiyi Miao, Yunshi Zhang, Hengchang Zang
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Nanostructured lipid carriers (NLCs): A promising candidate for lung cancer targeting Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Vaibhav Rajoriya, Ravikant Gupta, Sudha Vengurlekar, Upama Surendra Singh
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Magnetic Lipid-Based hybrid nanosystems: A combined stimuli- responsive nanocarriers for enriched chemotherapeutic potential of L-carnosine in induced breast Ehrlich ascites tumor model Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-15 Passent M.E. Gaafar, Ragwa M. Farid, Heba A. Hazzah, HussamElDin Y. AbouKilila, Maged W. Helmy, Ossama Y. Abdallah
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Fabrication and characterization of anthocyanin-loaded double Pickering emulsions stabilized by β-cyclodextrin Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-14 Yibo Pan, Xiaoqiang Ma, Jianxia Sun, Weibin Bai
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Exploring the immunomodulatory properties of glucan particles in human primary cells Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-14 Sandra Jesus, João Panão Costa, Mariana Colaço, Filipa Lebre, Daniela Mateus, Ana Isabel Sebastião, Maria T. Cruz, Ernesto Alfaro-Moreno, Olga Borges
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Biorelevant subcutaneous in vitro test predicts the release of human and fast acting insulin formulations Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-14 Tim A. Schöner, Verena Vogel, Marta Venczel, Katharina Knoth, Walter Kamm, Tobias Paehler, Guillaume Louit, Iria Torres Terán, Patricia Mundinger, Alexander Marker, Petra Loos, Marius Hittinger, Claus-Michael Lehr
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Zeta potential changing self-nanoemulsifying drug delivery systems: A newfangled approach for enhancing oral bioavailability of poorly soluble drugs Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-14 Amina Arshad, Shumaila Arshad, Alamgeer, Arshad Mahmood, Mulazim Hussain Asim, Muhammad Ijaz, Hafiz Muhammad Irfan, Mavra Rubab, Shujaat Ali, Ahmed Raza Hashmi
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Food selection and effect of home preparation procedure for antibiotic food mixtures on homogeneity, stability, and dissolution Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-13 Rong Huang, Dongkai Zhu, Jiang Wang, Yvonne Berko, Patricia A. Yu, Corinne M. Parker, Yon C. Yu, Xin Feng, Xiaoming Xu, Muhammad Ashraf
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Assessment of chitosan-coated zinc cobalt ferrite nanoparticle as a multifunctional theranostic platform facilitating pH-sensitive drug delivery and OCT image contrast enhancement Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-13 Dhruba Dhar, Subhadip Ghosh, Sayan Mukherjee, Santanu Dhara, Jyotirmoy Chatterjee, Soumen Das
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Fabrication and in-vivo evaluation of polyvinyl pyrrolidone/poloxamer 188 hybrid nanofibers of Deflazacort Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-12 Dalia H. Abdelkader, Abeer M. Belal, Eman A. Elkordy, Naglaa I. Sarhan, Ebtessam A. Essa
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Studying the ssDNA loaded adeno-associated virus aggregation using coarse-grained molecular dynamics simulations Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-12 Tibo Duran, Shivangi Naik, Leila Sharifi, Willow R. DiLuzio, Arani Chanda, Bodhisattwa Chaudhuri
Measurement of the center of mass (COM) distance between two empty capsids at 300 K (green line), two full capsids at 300 K (blue line), two empty capsids at 338 K (black line) and two full capsids at 338 K (red line).
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Polymer-lipid hybrid nanomedicines to deliver siRNA in and against glioblastoma cells Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-12 Arianna Rinaldi, Florence Dumas, Jason Thomas Duskey, Carol Imbriano, Silvia Belluti, Charlotte Roy, Ilaria Ottonelli, Maria Angela Vandelli, Barbara Ruozi, Emmanuel Garcion, Giovanni Tosi, Frank Boury
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Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Tanvi Karve, Ajay K. Banga
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Effect of hydroxyethyl starch on drug stability and release of semaglutide in PLGA microspheres Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Han Zeng, Jiaxin Song, Yiyao Li, Chen Guo, Yu Zhang, Tian Yin, Haibing He, Jingxin Gou, Xing Tang
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Enhancing precision medicine: Bispecific antibody-mediated targeted delivery of lipid nanoparticles for potential cancer therapy Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Yue Zhang, Xiaoyan Gu, Lili Huang, Yani Yang, Jun He
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Ternary solid dispersions of lacidipine: Enhancing dissolution and supersaturation maintenance through strategic formulation optimization Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Jian Shen, Anna Hu, Yuxin Yang, Ting Nie, Siqi Huang, Zeneng Cheng, Wenjie Liu
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Resorbable nanofibrous membranes for local and sustained co-delivery of acyclovir and ketorolac in herpes therapy Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Shih-Jyun Shen, Pin-Chao Feng, Ren-Chin Wu, Yi-Hua Kuo, Shih-Jung Liu, Hiroshi Ito
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Unveiling the challenges of engineered protein corona from the proteins’ perspective Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-11 Cintia Marques, Gerrit Borchard, Olivier Jordan
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Triple combination dry powder formulation of pretomanid, moxifloxacin, and pyrazinamide for treatment of multidrug-resistant tuberculosis Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-09 Claire Fan, Basanth Babu Eedara, Shubhra Sinha, Mohammad Khaja Mafij Uddin, Colin Doyle, Sayera Banu, Shyamal C. Das
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Polydispersity-mediated high efficacy of an in-situ aqueous nanosuspension of PPEF.3HCl in methicillin resistant Staphylococcus aureus sepsis model Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-08 Amit S. Lokhande, Vikas Maurya, Komal Rani, Palak Parashar, Rajni Gaind, Vibha Tandon, Padma V. Devarajan
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Phosphatase-degradable nanoparticles providing sustained drug release Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Summonte Simona, Eva Sanchez Armengol, Fabrizio Ricci, Matthias Sandmeier, Nathalie Hock, Ayse Güclü-Tuncyüz, Andreas Bernkop-Schnürch
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A strategy to optimize precompression pressure for tablet manufacturing based on in-die elastic recovery Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Gerrit Vreeman, Changquan Calvin Sun
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Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Romchat Chutoprapat, Jatuporn Witarat, Panalee Jongpanyangarm, Lucy Mang Sung Thluai, Pichanon Khankaew, Lai Wah Chan
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Development of new nanofibrous nerve conduits by PCL-Chitosan-Hyaluronic acid containing Piracetam-Vitamin B12 for sciatic nerve: A rat model Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Zahra Jafarisavari, Jafar Ai, Seyed Abbas Mirzaei, Mostafa Soleimannejad, Shiva Asadpour
Schematic image of conduit fabrication (sheets and tubular nerve conduits) by electrospinning technique; conduit characterization tests: Scanning electron microscopy (SEM), Attenuated total reflectance (ATR)-Fourier Transforms Infrared (FTIR) spectroscopy, Surface hydrophilicity test (Contact angle), Mechanical tests, 4′,6-diamidino-2-phenylindole (DAPI); study: Implantation of nanofibrous tubular
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In-situ forming biodegradable implants for sustained Fluocinolone acetonide release to the posterior eye: In-vitro and in-vivo investigations in rabbits Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Malihe Karimi, Mojtaba Abrishami, Mehdi Farzadnia, Hossein Kamali, Bizhan Malaekeh-Nikouei
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Hydrophilic and hydrophobic drug release from core (polyvinylpyrrolidone)-sheath (ethyl cellulose) pressure-spun fibers Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Nanang Qosim, Hamta Majd, Suguo Huo, Mohan Edirisinghe, Gareth R. Williams
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A novel approach to wound healing: Green synthetic nano-zinc oxide embedded with sodium alginate and polyvinyl alcohol hydrogels for dressings Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Tao You, Qixiu You, Xiaoyan Feng, Hui Li, Bo Yi, Hengyi Xu
Created by biorender.com and PowerPoint.
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Dexamethasone nanomedicines with optimized drug release kinetics tailored for treatment of site-specific rheumatic musculoskeletal diseases Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-07 Alena Libánská, Eva Randárová, Daniela Rubanová, Svitlana Skoroplyas, Josef Bryja, Lukáš Kubala, Rafał Konefal, Adéla Navrátilová, Lucie A. Cerezo, Ladislav Šenolt, Tomáš Etrych
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Bottom-up production of injectable itraconazole suspensions using membrane technology Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-06 Fatima Anjum, Thaïsa Viville, Snehashis Nandi, Maximilian Wessner, Bruno De Witte, Alain Collas, Gabriele Sadowski
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Multifunctionality of cyclodextrin-based polymeric nanoparticulate delivery systems for chemotherapeutics, combination therapy, and theranostics Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-06 Lakshmi Sathi Devi, Cristina Casadidio, Maria Rosa Gigliobianco, Piera Di Martino, Roberta Censi
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Fisetin nanoparticles based on cells cycle and apoptosis intervention for the treatment of lymphoma and leukemia Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-06 Tingting Yang, Hongfeng Gou, Ting Lin, Yunfan Yang, Xuelian Jin, Tian Dong, Yuanyuan Zhang, Xinchuan Chen.
Preparation of Fisetin NPs and their effects on tumors. Fisetin NPs composed of mPEG-PCL and fisetin were prepared via the self-assemble method. After entering cells, Fisetin NPs released fisetin that arrested cells cycle by downregulating Cyclin D1, CDK4, Cyclin B1 and CDC2 proteins, induced apoptosis by upregulating cleaved caspase 9, cleaved caspase 3 and cleaved PARP proteins, and bound to NAT10
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Co-delivery of siBcl-2 and PTX with mitochondria-targeted functions to overcoming multidrug resistance Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-05 Zhangliqiao, Xinyu Cao, Jiayi Chen, Yanyan Dong, Wenwen Chen, Yu Gao, Jingjing Guo, Haiqin Huang
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Critical attributes of fine excipient materials in carrier-based dry powder inhalation formulations: The particle shape and surface properties Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-05 Mustafa M.A. Elsayed, Iman M. Alfagih, Katrina Brockbank, Alhassan H. Aodah, Raisuddin Ali, Khaled Almansour, Ahmed O. Shalash
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Appraisal of folate functionalized bosutinib cubosomes against hepatic cancer cells: In-vitro, In-silico, and in-vivo pharmacokinetic study Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-05 Raquibun Nisha, Pranesh Kumar, Nidhi Mishra, Priyanka Maurya, Shakir Ahmad, Neelu Singh, Shubhini A. Saraf
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Investigating wound healing potential of sesamol loaded solid lipid nanoparticles: Ex-vivo, in vitro and in-vivo proof of concept Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-05 Parneet Kaur Deol, Indu Pal Kaur, Ravi Dhiman, Harmanjot Kaur, Garima Sharma, Parveen Rishi, Deepa Ghosh
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Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-04 Zitong Shao, Kingsley King-Gee Tam, V.P.K. Achalla, Esther C.Y. Woon, A. James Mason, Shing Fung Chow, Wing Cheong Yam, Jenny K.W. Lam
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Doxorubicin loaded cerium substituted hydroxyapatite nanoparticles: A promising new therapeutic approach for bone regeneration, doxorubicin delivery, and cancer treatment Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-03 Mona Moaness, Sahar M. Mousa, Mahmoud T. Abo-Elfadl, Gehan T. El-Bassyouni
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Co-release of paclitaxel and encequidar from amorphous solid dispersions increase oral paclitaxel bioavailability in rats Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-03 Emilie Fynbo Petersen, Bjarke Strøm Larsen, Rasmus Blaaholm Nielsen, Ils Pijpers, Dries Versweyveld, René Holm, Ingunn Tho, Jan Snoeys, Carsten Uhd Nielsen
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Design of liposomal nanocarriers with a potential for combined dexamethasone and bevacizumab delivery to the eye Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-03 Umer Farooq, Niall J. O'Reilly, Zubair Ahmed, Paolo Gasco, Thakur Raghu Raj Singh, Gautam Behl, Laurence Fitzhenry, Peter McLoughlin
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Optimization of Naringenin-loaded nanoparticles for targeting of Vanin-1, iNOS, and MCP-1 signaling pathway in HFD-induced obesity Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-02 Ahmed Salah, Nada Mohammed El-Laban, Seikh Mafiz Alam, Mohammad Shahidul Islam, Mohammed Abdalla Hussein, Tamer Roshdy
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Polydopamine-based nano adjuvant as a promising vaccine carrier induces significant immune responses against Acinetobacter baumannii-associated pneumonia Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-02 Samira Sabzi, Mehri Habibi, Farzad Badmasti, Shahla Shahbazi, Mohammad Reza Asadi Karam, Mehdi Farokhi
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OXPHOS-targeted nanoparticles for boosting photodynamic therapy against hypoxia tumor Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-02 Yujuan Gao, Yunhao Li, Zian Pan, Chenlu Xu, Xiaoyu Zhang, Mingjun Li, Weifeng Wang, Fan Jia, Yan Wu
Scheme 1. Schematic diagram of the formation of ATO and IR780 co-loaded mitochondrial targeting nanoparticles (TNPs/IA) for efficient photodynamic therapy against the solid tumor.
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Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-01 Tom de Waal, Niklas Handin, Joachim Brouwers, Marc Miserez, Ilse Hoffman, Maissa Rayyan, Per Artursson, Patrick Augustijns
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Baicalein glycymicelle ophthalmic solution: Preparation, in vitro antimicrobial activities, and antimicrobial mechanism evaluations Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-01 Jing Zhang, Yuhang Li, Sibin Xie, Huadong Lou, Hao Chen, Guowen Zhang
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Neuroglia targeting nano-therapeutic approaches to rescue aging and neurodegenerating brain Int. J. Pharm. (IF 5.8) Pub Date : 2024-03-01 Manju Sharma, Nidhi Aggarwal, Jibanananda Mishra, Jiban Jyoti Panda
Nanoparticulate therapy in microglia-mediated neuronal protection against (i) DNA breakage; (ii) ROS generation; (iii) mitochondrial dysfunction; (iv) protein aggregation; (v) oxidative DNA damage.
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Mannosylated polyethylenimine-cholesterol-based nanoparticles for targeted delivery of minicircle DNA vaccine against COVID-19 to antigen-presenting cells Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-29 Dalinda Eusébio, Milan Paul, Swati Biswas, Zhengrong Cui, Diana Costa, Ângela Sousa
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Interactions of oral permeation enhancers with lipid membranes in simulated intestinal environments Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-29 Nanna Wichmann Larsen, Serhii Kostrikov, Morten Borre Hansen, Claudia Ulrich Hjørringgaard, Niels Bent Larsen, Thomas Lars Andresen, Kasper Kristensen
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A new insight into the mechanism of the tabletability flip phenomenon Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-28 Zijian Wang, Chenguang Wang, Yiwang Guo, Deepak Bahl, Alex Fok, Changquan Calvin Sun
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Cocrystallization improves the tabletability of ligustrazine despite a reduction in plasticity Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-28 Gerrit Vreeman, Danyingzi Guan, Yuncheng Cai, Qun Zhou, Changquan Calvin Sun
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QbD-driven development and characterization of superparamagnetic iron oxide nanoparticles (SPIONS) of a bone-targeting peptide for early detection of osteoporosis Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-28 Anjali Pant, Gurpal Singh, Ravi Pratap Barnwal, Teenu Sharma, Bhupinder Singh
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Co-spray dried inhalable composite powders of ciprofloxacin and alginate oligosaccharide as anti-biofilm therapy Int. J. Pharm. (IF 5.8) Pub Date : 2024-02-27 Li Zhang, Hriday Bera, Yi Guo, Changzhi Shi, Johan Ulrik Lind, Carmen Radeke, Junwei Wang, Hengzhuang Wang, Xia Zhao, Dongmei Cun, Mingshi Yang
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