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Sequential assembly of DNA nanoparticles inside cells enables lysosome interference and cell behavior regulation Nano Today (IF 17.4) Pub Date : 2024-03-08 Sen Yang, Yu Cheng, Mingxing Liu, Jianpu Tang, Siqi Li, Yan Huang, Xiaohong Kou, Chi Yao, Dayong Yang
The artificial manipulation of exogenous molecules in living cells is a promising means to regulate cellular behaviors. However, the spatiotemporal control of self-assembly within the complex intracellular environment remains grand challenge. Herein, we report a controlled sequential assembly of DNA nanoparticles in living cells, responding to acidic environment in lysosome, which enables lysosome
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Cuprous oxide nanocomposites with photothermal (PTT) and chemical dynamics (CDT) effects induce cuproptosis in breast cancer using the strategy of increasing inflow and reducing outflow Nano Today (IF 17.4) Pub Date : 2024-03-08 Wei Li, Yao Xiao, Guohu Guo, Jiaxin Peng, Nan Zhu, Zekai Chen, Bin Peng, Zhaojun Jiang, Ben Li, Guifang Yu, Zhaoze Guo, Min Liang, Weihong Guo
Chemotherapy is a crucial adjuvant method of treating breast cancer, but it fails to achieve preferable prognosis as the malignant cells eventually develop drug-resistance. Reduced chemotherapeutic sensitivity is primarily caused by endogenous and exogenous resistance during the treatment. Cuproptosis is a newly discovered immunogenic cell death (ICD), characterized by accumulation of copper (Cu) ions
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High spatiotemporal tracking of intestinal peristalsis and bowel disease via in situ generated NIR-II cyanine-albumin complex Nano Today (IF 17.4) Pub Date : 2024-03-07 Fapu Wu, Senyao Liu, Bingbing Zheng, Wenwen Cao, Yu Zhu, Jieyu Yang, Hu Xiong
Real-time monitoring of intestinal movement is critical for the clinical diagnosis of bowel diseases, however, the application of organic fluorophores in non-invasive imaging of the intestinal tract via systemic administration is still challenging. We herein report a series of albumin-chaperoned chloro-cyanine dyes for high spatiotemporal tracking of intestinal peristalsis and bowel disease in vivo
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Elaboration a ROS-responsive darutigenol prodrug nanoassemblies for inflammatory arthritis treatment Nano Today (IF 17.4) Pub Date : 2024-03-06 Hui Yan, Danping Wang, Chengyin Tian, Long Zhao, Yong Wang, Guoqing Long, Bingjun Sun, Jingming Jia, Anhua Wang
Darutigenol (DL) is an active diterpenoid extracted from the traditional Chinese medicine (Makino) Makino, widely employed in the treatment of rheumatoid arthritis (RA) for centuries in China. However, the anti-inflammatory mechanism of DL requires further exploration. In this study, we discovered that DL could scavenge reactive oxygen species (ROS) and nitric oxide (NO), and reduce the secretion of
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Heterostructural covalent organic framework/polymer composite materials: Recent advances in multidisciplinary applications Nano Today (IF 17.4) Pub Date : 2024-03-04 Minh Kim Nguyen, Jin Seog Gwag, Lam Nguyen-Dinh, Hai Bang Truong, Ha Huu Do, Young-Chul Lee, Nguyen Tien Tran, Le Gia Trung
Porous materials with many advantages, including interesting structures and specific features, are indispensable for industry and daily life. Lately, the development of emerging porous substances has animatedly materialized thanks to their superior characteristics for multidisciplinary applications. As a novel and outstanding platform for porous crystalline products, covalent organic frameworks (COFs)
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Hazard assessment of nanomaterials using in vitro toxicity assays: Guidance on potential assay interferences and mitigating actions to avoid biased results Nano Today (IF 17.4) Pub Date : 2024-03-02 Naouale El Yamani, Elise Rundén-Pran, Julia Varet, Maja Beus, Maria Dusinska, Valérie Fessard, Elisa Moschini, Tommaso Serchi, Mihaela Roxana Cimpan, Iseult Lynch, Ivana Vinković Vrček
The movement towards an animal-free testing approach for risk assessment represents a key paradigm shift in toxicology. Risk assessment of engineered and anthropogenic nanoscale materials (NM) is dependent on reliable hazard characterization, which requires validated test methods and models, and increasingly on mechanistic insights into the mode of action. The properties that make NMs so advantageous
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Biomimetic bacteria-derived nanoclusters enhance ferroptosis cancer immunotherapy through synergistic CRISPR-photothermo modulation Nano Today (IF 17.4) Pub Date : 2024-02-29 Xiuhua Pan, Jie Yang, Ruixin Kang, Jun Zhang, Zongwei Hu, Ning Yang, Zengyi Liu, Zengguang Jia, Xiawei Zhou, Qi Shen
The induction of ferroptosis in cancer cells has emerged as a promising approach to initiate immunogenic cell death (ICD). However, the limited production of lipid peroxidation (LPO) considerably undermines the effectiveness of ferroptosis. In this work, T7 polypeptide engineered bacterial outer membrane vesicles (T7-OMVs) co-delivering plasmids and melanin nanoparticles (MNPs) are fabricated into
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A Janus nanofibrous scaffold integrated with exercise-driven electrical stimulation and nanotopological effect enabling the promotion of tendon-to-bone healing Nano Today (IF 17.4) Pub Date : 2024-02-29 Qian Zhang, Jianhua Zhu, Xiang Fei, Meifang Zhu
Rotator cuff tear and repair presents a significant challenge on a global scale due to the ineffectiveness of current treatments involving single sutures or synthetic scaffolds in achieving genuine healing of complex and heterogeneous tendon and bone. Wireless bioelectrical therapy is emerging as a promising approach to overcome the existing limitations. Herein, a Janus nanofibrous scaffold with piezoelectric
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Construction of tumor-cell nucleus targeting lanthanide nano-prodrugs with lutetium-177 labelling for high-efficient tumor fluorescence-localization and radionuclide therapy Nano Today (IF 17.4) Pub Date : 2024-02-28 Zhifen Wu, Hao Chen, Hongyun Zhang, Lixiang Ye, Jianxi Ke, Yongsheng Liu, Pengming Sun, Maochun Hong
Tumor-cell nucleus targeting is highly desired for theragnostic nano-prodrugs (NPDs) to enhance cancer diagnostic and therapeutic efficacy as compared to those targeting the cytoplasm or other intracellular organelles. This study presents a well-designed tumor-cell nucleus targeting theragnostic NPD called Lu-YNP@FA that can not only deliver bright upconversion/NIR-II fluorescence but also emit radioactive
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Procoagulant CaCO3-embedded embolic microspheres can potentiate transcatheter arterial embolization of hepatocellular carcinoma Nano Today (IF 17.4) Pub Date : 2024-02-28 Ziliang Dong, Lei Zhang, Dongxu Zhao, Chunjie Wang, Yu Hao, Quguang Li, Yunyun Zhang, Zhijuan Yang, Caifang Ni, Zhuang Liu, Liangzhu Feng
Transcatheter arterial embolization (TAE) represents a preferred therapeutic modality with minimal invasiveness for unresectable intermediate and advanced hepatocellular carcinoma (HCC) patients. However, its therapeutic outcome is restricted by incomplete occlusion of the whole tumor vasculature and exacerbated tumor immunosuppression due to the lack of ideal embolic agents. Herein, procoagulant embolic
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In-flight electro-neutralisation electrospray for pulmonary drug delivery Nano Today (IF 17.4) Pub Date : 2024-02-27 Hoai-Duc Vu, Trung-Hieu Vu, Ngoc Luan Mai, Deeptee Chandrashekhar Pande, Dzung Viet Dao, Bernd H.A. Rehm, Nam-Trung Nguyen, Gary D. Grant, Canh-Dung Tran, Yong Zhu, Van Thanh Dau
Pulmonary drug delivery does not only provide non-invasive therapy for local lung diseases but also remarkably enhances systemic absorption of therapeutics owing to the tremendous surface area of the lung and fast transport of active molecules across the respiratory epithelia. In comparison to traditional delivery systems, electrohydrodynamic atomisation (EHDA) is superior in terms of size and production
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Multi-prospects of bacterial extracellular vesicles in immune modulation, inflammation regulation, and periodontitis treatment Nano Today (IF 17.4) Pub Date : 2024-02-26 Yiqin Jiang, Yunxin Chen, Linhu Ge, Lijing Wang, Liping Wang, Janak L. Pathak
Periodontitis is a chronic and multifactorial inflammatory oral disease that not only causes alveolar bone loss and tooth loosening but also amplifies systemic inflammation. Breakdown of periodontal host-microbe homeostasis creates dysbiotic microbial communities of keystone pathogens that trigger the host immune response creating a pro-inflammatory milieu in the periodontal region. Keystone pathogens
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Intelligent micro/nanomotors: Fabrication, propulsion, and biomedical applications Nano Today (IF 17.4) Pub Date : 2024-02-26 Jiamin Ye, Yueyue Fan, Gaoli Niu, Baoli Zhou, Yong Kang, Xiaoyuan Ji
Intelligent micro/nanomotors (MNMs) are unique devices at the micro- or nanoscale that achieve active movement in various liquid environments by converting different forms of energy into mechanical motion, making them highly promising in the field of biomedical applications. This review provides a comprehensive overview of the fabrication methodologies, propulsion mechanisms, and burgeoning landscape
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STING antagonist-loaded renal tubule epithelial cell-mimicking nanoparticles ameliorate acute kidney injury by orchestrating innate and adaptive immunity Nano Today (IF 17.4) Pub Date : 2024-02-26 Yuqi Shen, Fengmin Yang, Feng Wu, Mengmeng Zhang, Bo Deng, Zhenkai Wu, Jiaolun Li, Yue Shen, Lu Wang, Feng Ding, Jinyao Liu
Inflammatory responses profoundly contribute to the development of renal damage in acute kidney injury (AKI), a frequent clinical syndrome with high morbidity and mortality. However, the effects of existing strategies aiming to suppress the inflammation in AKI remain unsatisfactory due to the inability to simultaneously regulate innate and adaptive immune responses. Here, STING antagonist-loaded renal
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Stimuli-responsive graphdiyne-silver nanozymes for catalytic ion therapy of dental caries through targeted biofilms removal and remineralization Nano Today (IF 17.4) Pub Date : 2024-02-26 Jing Liao, Ludan Zhang, Baoyun Sun, Dongmei Wang, Zhiyong Zhang, Wenjie Ma, Zhe Wang, Yuguang Wang, Qiang Wang, Wenyan Yin, Zhanjun Gu
Clinical mechanical decontamination and irrigants are not consistently effective in preventing intractable biofilm-induced dental caries, especially when biofilms have caused demineralization. Constructing stimuli-responsive nanocatalysts with improved catalytic activity for plaque biofilm removal and remineralization enhancement remains challenging. Herein, a coordination-reduction strategy driven
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Ultrasmall AuCe nanozyme adjuvant boosted ROS for three-pronged tumor immunotherapy Nano Today (IF 17.4) Pub Date : 2024-02-26 Xinyi Lu, Ziwei Chen, Yang Li, Yuecong Guo, Zhenzhen Wang, Shuhan Zhang, Zhichao Wang, Xin Wang, Susu Gao, Tong Guan, Ru Bai, Mengyu Guo, Huige Zhou, Xingfa Gao, Kai Zhang, Yanyan Cui, Chunying Chen, Yaling Wang
Catalytic tumor immunotherapy presents a new combination of nanozymes and immunotherapy agents, but the final therapeutic outcomes are usually diminished by insufficient nanozyme activity, immunosuppressive tumor microenvironment (TME), and poor antigen delivery efficiency. Herein, a bimetallic nanozyme-based tumor immunotherapy nanovaccine is first proposed to address these limitations by attenuating
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Remotely disturbing bioelectrical homeostasis by nanoparticle-enabled intracellular electrical stimulation for wireless cancer therapy Nano Today (IF 17.4) Pub Date : 2024-02-24 Cairong Xiao, Lei Fan, Changhao Li, Lei Zhou, Chunlin Deng, Rumin Fu, Dafu Chen, Zhengao Wang, Jinxia Zhai, Guoxing Tan, Peng Yu, Chengyun Ning, Chuanbin Mao
Bioelectrical homeostasis plays critical roles in biological processes, but disturbing it for cancer therapy remains challenging due to the difficulty in electrically controlling cancer cells. Here we show that cell-internalized electroactive nanoparticles interrupt it in cancer cells to effectively treat cancer wirelessly. Specifically, KNaNbO ferroelectric nanoparticles are polarized and then generate
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Ultrasound-mediated intra-/extracellular dual intervening effect combined with all-trans retinoic acid for cancer stemness inhibition Nano Today (IF 17.4) Pub Date : 2024-02-23 Yutong Zhu, Tianzhi Liu, Xi Deng, Danli Sheng, Jufeng Chen, Yichen Kuang, Zideng Dai, Hangrong Chen
Cancer stem cells (CSCs), characterized by robust self-renewal capacity and varied differentiation potential, are considered pivotal in the ineffectiveness of cancer therapy. Some strategies targeting CSCs may exhibit limited efficacy due to the rigid extracellular matrix (ECM) in tumor region that still maintains stemness through mechanosensitive pathways. Herein, an ultrasound (US)-mediated intra/extracellular
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Ultra-high antioxidant, anti-apoptosis and pro-angiogenesis effect of Mo2C nanosheets for treatment of diabetic wounds Nano Today (IF 17.4) Pub Date : 2024-02-15 Yaping Ren, Xiaolin Zhou, Xuejiao Gao, Jingjing Si, Wenhui Ren, Caixia Li, Qi Yang, Yunlong Zhou, Feng Bai, Weiwei He
Diabetic wounds are prevalent complications of diabetes and are difficult to heal because of the complicated pathophysiology. Considering the multifactorial pathogenesis and clinical needs, the combined multifunctional therapy represents the efficient solution for diabetic wound healing, and the key is to find suitable agents possessing multiple responses.Here, we present a two-dimensional (2D) ultrathin
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Gut microbiota dysbiosis mediates mouse kidney fibrosis induced by black phosphorus quantum dots Nano Today (IF 17.4) Pub Date : 2024-02-15 Fengkai Ruan, Jie Zeng, Changqian Liu, Jianrong Han, Naying Zheng, Kun Li, Hanying Yin, Mingtao Wu, Xiaoyan Ding, Changshun Han, Lingtao Yang, Chunyan Yang, Dai Wang, Nengming Xiao, Zhenghong Zuo, Chengyong He
As a novel type of nanomaterials, black phosphorus quantum dots (BPQDs) have wide application potential, including anti-pathogenic bacteria. However, there is no information on the effects of BPQDs on the symbiotic bacteria after oral exposure. In our study, mice were daily oral administrated to 0.1 and 1 mg/kg BPQDs for 28 days. We found that BPQDs caused gut microbiota dysbiosis and decreased the
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Ag-decorated multivariate metal-organic frameworks for enhanced sonodynamic therapy of bacterial infections in wound healing Nano Today (IF 17.4) Pub Date : 2024-02-14 Sirong Sun, Xiangdan Meng, Jingwen Xu, Zhou Yang, Xueji Zhang, Haifeng Dong
The wide energy band gap and sluggish electron transfer efficiency of emerging metal-organic frameworks (MOFs) sonosensitizers severely impaired the therapeutic effectiveness of sonodynamic therapy (SDT). Herein, we prepare an engineered MOF composition consisting of multivariate MOFs and further in-situ surface decoration of Ag nanoparticles (Ag@UT) for enhanced SDT of bacterial infections in wound
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Harnessing self-assembled nanoplatform of Dexamethasone and α-linolenic acid for high-efficiency inhibition of pulmonary cytokine storm and fibrosis in mice Nano Today (IF 17.4) Pub Date : 2024-02-13 Hongbing Liu, Muse Ji, Yi Qin, Yin Sun, Hanxun Wang, Peifu Xiao, Jiansong Zhao, Yaxin Deng, Zhen Zhang, Jingxin Gou, Tian Yin, Haibing He, Guoliang Chen, Xing Tang, Yu Zhang
Cytokine storm and pulmonary fibrosis caused by Coronavirus Disease 2019 (COVID-19) are the two major culprits threatening human life and health. Herein, we engineered a novel disulfide-bridged carrier-free prodrug self-assembled nanoparticles (DSSL NPs) composed of Dexamethasone (Dex) and α-linolenic acid (LNA) for synergistic inhibition of cytokine storm and pulmonary fibrosis. DSSL NPs possess the
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Application of room-temperature phosphorescent carbon dots in information encryption and anti-counterfeiting Nano Today (IF 17.4) Pub Date : 2024-02-13 Linlin Shi, Luyao Ding, Yongqiang Zhang, Siyu Lu
Optical information encryption and security have garnered significant attention due to their close association with data protection and information security. The development of diverse stimuli-responsive optical materials for constructing advanced information encryption and security systems holds immense importance for practical applications. Room temperature phosphorescent (RTP) materials, characterized
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Hyperspectral imaging of complex dielectric functions in 2D materials Nano Today (IF 17.4) Pub Date : 2024-02-10 Un Jeong Kim, Yoojoong Han, Florence A. Nugera, Seok Joon Yun, Seok In Kim, Moonsang Lee, Humberto R. Gutiérrez, Young Hee Lee, Hyungbin Son
It remains a challenge to characterize inhomogeneities in two-dimensional (2D) layered materials associated with strain and defects. Spectroscopic ellipsometry and reflectance/transmittance measurement can be used to characterize complex dielectric functions. However, these techniques are not well suited for submicron spectroscopic imaging of inhomogeneities across a macroscale sample. Here, we report
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E-selectin-targeted polymer-doxorubicin conjugate induces regression of established colorectal liver metastases and improves mice survival Nano Today (IF 17.4) Pub Date : 2024-02-10 Marie Rütter, Nenad Milošević, Yvonne Ventura, Valeria Feinshtein, Ayelet David
Liver metastases arising from colorectal cancer (CRC) are a major challenge for cancer treatment, as they often emerge as unresectable and resistant to therapy. Novel treatments targeting the specific metastatic tumor microenvironment (TME) may improve the therapeutic outcome. One relevant receptor at the TME in the liver is the endothelial-expressed cell adhesion molecule E-selectin.
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Ultrasmall platinum nanoclusters: A potent chemotherapeutic drug for cancer-specific DNA damage with optimizing therapeutic efficacy while minimizing systemic toxicity Nano Today (IF 17.4) Pub Date : 2024-02-10 Chunyu Zhang, Na Zhang, Wenchao Niu, Ruihan Li, Yanna Liu, Yanling Mu, Chao Xu, Qingqiang Yao, Xueyun Gao
Platinum chemotherapy drugs, represented by cisplatin, have been widely used in cancer therapy. While they are effective, their use is limited by their adverse effects in long-term administration, especially the lack of selectivity and high systemic toxicity. Encouragingly, molecular-like platinum nanoclusters, as a bridge between nanomedical and small molecular drugs, provide an attractive opportunity
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Free-standing iridescent films: Crafting circularly polarized luminescence from blue to NIR-II for enhanced anti-counterfeiting performance Nano Today (IF 17.4) Pub Date : 2024-02-09 Xiaolei Li, Chengyu Jiang, Xuefeng Yang, Tonghan Zhao, Xue Jin, Shuang Jiang, Pengfei Duan
Circularly polarized luminescence (CPL) has recently garnered significant attention due to its promising applications. Current research efforts are predominantly concentrated on enhancing CPL emission with a specific focus on increasing both emission efficiency and luminescence dissymmetry factor (). Moreover, how to achieve large-scale fabrication of chiroptical materials with excellent CPL performance
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Sensitizing cuproptosis by endogenous copper-triggered bioorthogonal nanoremodeler Nano Today (IF 17.4) Pub Date : 2024-02-09 Jiawei Zhu, Yawen You, Wenting Zhang, Wenjie Wang, Minhao Jiang, Fang Pu, Jinsong Ren, Xiaogang Qu
Cuproptosis, a copper-dependent cell death modality identified recently, provides a new avenue for tumor treatment. However, the direct delivery of copper may disturb copper homeostasis of normal tissues and cause side effects. In addition, the metabolic reprogramming of cancer cells and intracellular environment-related biosynthesis of iron-sulfur (Fe-S) cluster proteins severely restrict their sensitivity
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Nanoparticles insert a three dimensional cavity structure of proteins for function inhibition: The Case of CeO2 and SARS-CoV-2 Nano Today (IF 17.4) Pub Date : 2024-02-08 Guofang Zhang, Xiaofeng Wang, Guocheng Wang, Xiaoman Suo, Yu Qiu, Rong-Hua Luo, Yingnan Liu, Qi Li, Wenhe Luo, Zhenzhen Shi, Fangfang Liu, Zhongda Li, Jing Qu, Liang Li, Neus G. Bastús, Martin Himly, Liming Wang, Feng-Liang Liu, Yong-Tang Zheng, Victor Puntes, Yang Li
The selective interaction of nanomaterials with proteins for protein function suppression has been reported. However, whether the nanomaterials could be used to target a three-dimensional (3D) structure of proteins for the consequent function inhibition is not defined. When SARS-CoV-2 binds to the host cell surface ACE2 receptor, the spike protein trimer changes to an "Open State" which forms a 5 nm
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Degradable CRISPR/Cas9 nanosystem activated by NIR-II light targets genome editing of PD-L1 and metabolic modulation for enhanced antitumor immunity Nano Today (IF 17.4) Pub Date : 2024-02-08 Xiaoyi Zhao, Kangli Guo, Kai Zhang, Xiaokang Ding, Nana Zhao, Fu-Jian Xu
The disruption of the programmed cell death ligand-1 (PD-L1) on tumor cell membranes holds promise to augment T cell-mediated antitumor immunity. However, the permanent prevention of constant PD-L1 expression by Cas9-mediated editing with spatiotemporal specificity and modulation of immunosuppressive tumor microenvironment (TME) remains challenging. Herein, degradable photothermal nanocarriers (RPP)
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Microenvironment modulating nanogels by Shiitake-derived lentinan and a reactive oxygen species scavenging conjugated polymer for the treatment of Alzheimer’s disease Nano Today (IF 17.4) Pub Date : 2024-02-07 Yanru Xin, Fang Fang, Qiang Yue, Yong Luo, Sidan Tian, Lianghui Cheng, Xiaochuan Wang, Xiangliang Yang, Liang Luo, Fanling Meng
Microenvironment imbalances in the brain, including β-amyloid (Aβ) aggregation, inflammation, oxidative stress, , have been considered as a hallmark in the early stage of Alzheimer's disease (AD). Therapeutic strategies that can simultaneously modulate multiple disorders in the AD microenvironment are urgently needed to combat the intricate pathogenesis of AD. Here we present a nanogel system (PLNG)
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Inside Back Cover - Graphical abstract TOC/TOC in double column continued from OBC if required, otherwise blank page Nano Today (IF 17.4) Pub Date : 2024-02-06
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Ultrasound-mediated Cu2+/Cu+ redox cycling activates peroxymonosulfate for oxygen-independent reactive X species (X = O/S) therapy Nano Today (IF 17.4) Pub Date : 2024-02-06 Xue Wang, Lili Xia, Hui Cheng, Kexing Li, Wei Feng, Xinyue Dai, Yu Chen
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Spider silk-inspired tough materials: Multi-pathway synthesis, advanced processing, and functional applications Nano Today (IF 17.4) Pub Date : 2024-02-06 Yupei Su, Shuo Shi, Cong Wang, Zhuang Wang, Pengsong Li, Shuting Zhang, Bin Fei, Zhuohong Yang, Jinlian Hu
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A DNA nanocomplex with bifunctions of reactive oxygen species scavenging and gene silencing for synergistic repair of myocardial infarction Nano Today (IF 17.4) Pub Date : 2024-02-05 Jinqiao Liu, Yuhang Dong, Jianpu Tang, Junlin Wu, Yan Huang, Chi Yao, Dayong Yang
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Crab-shaped DNA tetrahedral nanomachine for silencing undruggable mRNA targets in prostate cancer Nano Today (IF 17.4) Pub Date : 2024-02-02 Fangning Wan, Zheng Liu, Junyu Zhang, Wei Zhang, Bo Dai
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Multi-ion controllable metal halide ionic structure for selective short- and long-term memorable synaptic devices Nano Today (IF 17.4) Pub Date : 2024-02-02 Daseul Lee, Seung-Jea Lee, Jae Ho Kim, Geonguk Kim, Wan-Gil Jung, Juyun Park, Yong-Cheol Kang, Young-Hoon Kim, Myungkwan Song, Han Seul Kim, Jin Woo Choi
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Self-generated double-stranded RNA for enhancing tumor immunotherapy and metastasis inhibition Nano Today (IF 17.4) Pub Date : 2024-02-01 Yulin Yu, Yinmei Tian, Yang Li, Xianya Qin, Xiaonan Li, Qian Hu, Chuansheng Fu, Boning Niu, Conglian Yang, Li Kong, Zhiping Zhang
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Reigniting the cancer-immunity cycle with nanoparticles for simultaneous delivery of oncolytic peptides and a TLR agonist Nano Today (IF 17.4) Pub Date : 2024-02-01 Bao Loc Nguyen, Cao Dai Phung, Duc-Vinh Pham, Ngoc Duy Le, Thi Oanh Oanh Nguyen, Siyoon Kim, Sung Giu Jin, Han-Gon Choi, Jae-Hoon Chang, Chang Hyun Song, Jeonghwan Kim, Sae Kwang Ku, Jong Oh Kim
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Functional separator materials of sodium-ion batteries: Grand challenges and industry perspectives Nano Today (IF 17.4) Pub Date : 2024-02-01 Zhixin Xue, Dongyang Zhu, Minghui Shan, Hongkang Wang, Jia Zhang, Guoshi Cui, Zexu Hu, Keith C. Gordon, Guiyin Xu, Meifang Zhu
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Inhalable biomimetic nanomotor for pulmonary thrombus therapy Nano Today (IF 17.4) Pub Date : 2024-01-30 Kai Zhang, Yuying Long, Shuting Li, Yanli Zhao, Heyou Han
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Bubble manipulation mediated by external stimuli: From bioinspired design to potential applications Nano Today (IF 17.4) Pub Date : 2024-01-29 Danna Liu, Yixuan Wang, Wei Chen, Ye Tian, Feilong Zhang, Shutao Wang, Jingxin Meng
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Flash ignition and application of materials: A review Nano Today (IF 17.4) Pub Date : 2024-01-29 Linge Guo, Runtian Yu, Guannan Liu, Dong Liu
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Cerenkov radiation shining a light for cancer theranostics Nano Today (IF 17.4) Pub Date : 2024-01-28 Minglei Teng, Xiaoliu Liang, Hui Liu, Zhenjie Li, Xing Gao, Chi Zhang, Hongwei Cheng, Hu Chen, Gang Liu
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Long-lifetime phosphorescence in diamond for data storage Nano Today (IF 17.4) Pub Date : 2024-01-26 Kuikui Zhang, Chenglong Shen, Longbin Yan, Yalun Ku, Chunxiang Zhao, Qing Lou, Jinhao Zang, Chunyao Niu, Shaobo Cheng, Shunfang Li, Chong-Xin Shan
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Self-assembly of peptides: The acceleration by molecular dynamics simulations and machine learning Nano Today (IF 17.4) Pub Date : 2024-01-25 Nana Cao, Kang Huang, Jianjun Xie, Hui Wang, Xinghua Shi
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The landscape of extracellular vesicles combined with intranasal delivery towards brain diseases Nano Today (IF 17.4) Pub Date : 2024-01-26 Jiale Li, Hanwen Zhang, Yingyu Jiang, Nengjin Li, Anran Zhu, Yingjie Zhang, Kuanhan Feng, Wei Zeng, Liuqing Di, Ruoning Wang
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Yeast-derived nanocarriers enable binary reprogramming macrophages for cancer immunotherapy Nano Today (IF 17.4) Pub Date : 2024-01-25 Junyi Che, Xiaoxuan Zhang, Guangtao Gao, Yu Yang, Jingjing Gan, Kai Chen, Wei Xu, Yuanjin Zhao
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β3-adrenergic receptor methylation mediates fine particulate matter inhalation-impaired white adipose tissue browning Nano Today (IF 17.4) Pub Date : 2024-01-24 Renjie Hu, Jing Pan, Junyao Zhu, Sanduo Li, Guoqing Zhang, Pengpeng Wang, Wenhui Zhang, Lu Zhang, Li Qin, Ran Li, Weijia Gu, Rucheng Chen, Yunhui Zhang, Kezhong Zhang, Qinghua Sun, Sanjay Rajagopalan, Cuiqing Liu
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Cascade-targeting multifunctional nanochaperone remodels brain microenvironment for synergistic therapy of Alzheimer’s disease Nano Today (IF 17.4) Pub Date : 2024-01-22 Xiaochen Zhang, Haodong Hu, Qiushi Li, Yu Zhao, ZhanZhan Zhang, Shuyue Zhao, Linlin Xu, Rujiang Ma, Fan Huang, Linqi Shi
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FeS-based cascade bioreactors driven by Shewanella oneidensis MR-1 for efficient chemodynamic therapy with augmented antitumor immunity Nano Today (IF 17.4) Pub Date : 2024-01-22 Min Xi, Zheng Deng, Cai Zhang, Xirui Wu, Lin Zhang, Yifan Zhang, Xianglong Sun, Jinhua Zhou, Guangbao Yang
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Manufacturing and applications of multi-functional holey two-dimensional nanomaterials – A review Nano Today (IF 17.4) Pub Date : 2024-01-22 Dini Wang, Yan Dou, Xing Zhang, Kun Bi, Iyyappa Rajan Panneerselvam, Haofan Sun, Xinyu Jiang, Rui Dai, Kenan Song, Houlong Zhuang, Yongfeng Lu, Yan Wang, Yiliang Liao, Ling Ding, Qiong Nian
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Pore-enhanced reactive oxygen species generation by using covalent organic frameworks for improving sonodynamic therapy of cancer Nano Today (IF 17.4) Pub Date : 2024-01-22 Yikai Tang, Lei Ge, Lei Jiang, Xiqun Jiang
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A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections Nano Today (IF 17.4) Pub Date : 2024-01-19 Jiexin Li, Qian Qiu, He Ren, Jingyu Zhang, Chen Zhang, Gengqi Liu, Boyang Sun, Bin Zheng, Jonathan F. Lovell, Yumiao Zhang
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Electrospun nanofiber as building blocks for high-performance air filter: A review Nano Today (IF 17.4) Pub Date : 2024-01-20 Hui Liu, Yanting Zhu, Chenwei Zhang, Yangqi Zhou, Deng-Guang Yu
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Anti-PEG antibodies: Current situation and countermeasures Nano Today (IF 17.4) Pub Date : 2024-01-19 Jiaru Fu, Ercan Wu, Guanghui Li, Bin Wang, Changyou Zhan
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Rational design of polymeric micelles for targeted therapeutic delivery Nano Today (IF 17.4) Pub Date : 2024-01-18 Yuting Zheng, Yavuz Oz, Yimin Gu, Nadim Ahamad, Kaavian Shariati, Jose Chevalier, Diya Kapur, Nasim Annabi
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Corrigendum to ‘Macromolecular carrier with long retention and body-temperature triggered nitric oxide release for corneal alkali burn therapy via leptin-related signaling’ [Nano Today 54 (2024) 102108] Nano Today (IF 17.4) Pub Date : 2024-01-15 Qiyu Qin, Min Chen, Naiji Yu, Ke Yao, Xin Liu, Qi Zhang, Youxiang Wang, Jian Ji, Kaijun Wang, Fan Jia
Abstract not available