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Role of Nanoformulations in the Treatment of Lung Cancer Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-02-07 Parijat Pandey, Gunjan Nautiyal, Deepika Purohit, Sneh lata, Virender Kumar, Manish Makhija, Deeksha Manchanda, Neha Minocha, Sunil Kumar, Deepak Kaushik
: Lung cancer is the second deadliest disease in the world. A major portion of deaths related to cancer are due to lung cancer in both males and females. Interestingly, unbelievable advances have occurred in recent years through the use of nanotechnology and development in both the diagnosis and treatment of lung cancer. Due to their in vivo stability, the nanotechnology-based pharmacological system
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Formulation of Solid Lipid Nanoparticles Loaded with Rosiglitazone and Probiotic: Optimization and In-vitro Characterization Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-02-02 Nitish Kumar, Nidhi Tyagi, Sidharth Mehan, Alok Pratap Singh
Introduction: In the present study, solid lipid nanoparticles loaded with Rosiglitazone and probiotics were prepared via solvent emulsification diffusion. As a lipid and surfactant, Gleceryl monostearate and Pluronic -68 were used in the formulation process. background: Nanotechnology is essential for developing novel methods for transporting potentially therapeutic and symptomatic substances to specific
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Analysis of Lanthanum Oxide Based Double-Gate SOI MOSFET using Monte-Carlo Process Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-01-12 Pattunnarajam Paramasivam, Naveenbalaji Gowthaman, Viranjay. M. Srivastava
Introduction: This work proposes a Double-Gate (DG) MOSFET with a Single Material made of Silicon On-Insulator (SOI). The Lanthanum Oxide material with a high k-dielectric constant has been used as an interface between two gates and the channel. The Monte Carlo analysis has been used to determine the Conduction Band Energy (Ec) profiles and electron sheet carrier densities (ns) for a Silicon channel
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Wheatgrass (Triticum Aestivum) Extract Loaded Chitosan Solid Lipid Nanoparticles: Formulation, Physicochemical Characterisation and Cytotoxic Potential Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-01-12 Neha Minocha, Parijat Pandey, Nidhi Sharma, Sangita Saini
Background: The prevalence of cancer is around the world, and is identified as a multifarious ailment. Amongst the most common reasons for cancer in the world is oxidative stress, and this can be overcome by taking the herbal plant wheatgrass in any form. background: The prevalence of cancer is around the world and is identified as a multifarious ailment. Amongst the most common reasons of cancer in
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Vesicular Nanocarriers: A Potential Platform for Topical/Transdermal Delivery of Antibiotics Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-01-11 Mohit Chadha, Deepinder Singh Malik
Background: Bacterial infections are becoming difficult to treat nowadays due to the development of resistance towards conventional treatments. Conventional topical formulations loaded with antibiotics display various disadvantages, like high dosing frequency, high toxicity, and poor patient compliance. The former limitations may sometimes lead to severe complications and hospitalization of patients
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Approaches to Enhance the Stability of Colloidal Quantum Well Light- Emitting Diodes Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-01-11 Wenhui Fang, Baiquan Liu
Colloidal quantum well light-emitting diodes (CQW-LEDs) show great potential for applications in displays and lighting due to their advantages, such as high color purity, spectral tunability and compatibility with flexible electronics. So far, attention has been mainly devoted to pursuing device efficiencies rather than achieving device stability, leading to the fact that the lifetime of CQW-LEDs is
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Improved Thermal Performance and Distillate of Conventional Solar Still via Copper Plate, Phase Change Material and CuO Nanoparticles Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2024-01-04 S. Kumaravel, M. Nagaraj, G. Bharathiraja
Background:: The world is currently facing a growing concern regarding freshwater scarcity, which has arisen as a result of a complex interplay of various factors. Renewable energy-powered water desalination is a feasible solution to address freshwater scarcity. Methods:: This study presents a comprehensive investigation of the performance of a conventional solar still (CSS) and its modified versions
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Recent Patents on Solid Dispersions Emphasize Promising Benefits in Solubility Enhancement of Poorly Water-soluble Drugs Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-12-01 Manisha Saini, Shailender Bhatt, Harish Dureja, Neeta solanki
Background:: In the development of drug delivery systems, drugs' solubility remains the most challenging constraint. Many newly synthesized chemical compounds are available, but they involve low solubility and poor permeability restrictions. Among various drug delivery systems, the utilization of solid dispersion technologies has become more focused due to their promising benefits. Objective:: This
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Diabetology and Nanotechnology: A Compelling Combination Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-10 Ritu Karwasra, Shivkant Sharma, Isha Sharma, Nida Shahid, Tarana Umar
:: The convergence of diabetology and nanotechnology has emerged as a promising synergy with the potential to revolutionize the management and treatment of diabetes mellitus. Diabetes, a complex metabolic disorder affecting millions worldwide, necessitates innovative approaches to enhance monitoring, diagnosis, and therapeutic interventions. Nanotechnology, a burgeoning field that manipulates materials
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Applications of Nanomedicine in Brain Tumor Therapy: Nanocarrierbased Drug Delivery Platforms, CChallenges, and Perspectives Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-10 Ravinder Verma, Lakshita Rao, Harish Kumar, Nitin Bansal, Aakash Deep, Jatin Parashar, Manish Yadav, Vineet Mittal, Deepak Kaushik
Background:: The most difficult kind of cancer to treat is brain cancer, which causes around 3% of all cancer-related deaths. The targeted delivery is improved with the use of technologies based on nanotechnology that are both safe and efficient. Because of this, there is now a lot of research being done on brain cancer treatments based on nanoformulations. Objective:: In this review, the author's
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An Efficient Suppression of EGFR and B-Raf mRNA Overexpression in the Lung of Benzo[a]pyrene-induced mice by Cationic Lipo-ATRA Nanoformulation Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-10 Berlin Grace V M, David Wilson D, Siddikuzaman #, Viswanathan S, Ragavi R, Guruvayoorappan C, Kathirvelan C
Background:: The molecular drug all-trans retinoic acid (ATRA) acts on cancer cells via different molecular pathways, but its poor bioavailability in cancer cells limits its potency. This study was, therefore, carried out to analyse the oncogene expressions in the lung tissue of benzo[a]pyrene (B[a]P)-induced mice and compare between free ATRA and cationic liposome nanoformulation (lipo- ATRA) treatments
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Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-10 Vijay Agarwal, Meenakshi Bajpai
Background: Nanosizing is widely recognized as an effective technique for improving the solubility, dissolution rate, onset of action, and bioavailability of poorly water-soluble drugs. To control the execution and behavior of the output product, more advanced and valuable analytical techniques are required. Objective: The primary intent of this review manuscript was to furnish the understanding of
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Emerging Treatment Options of Pluronic in Designing Colloidal Nano and Microcarriers Carriers for Various Therapies Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-09 Ravinder Verma, Laxmi Rani, Sweta Kamboj, Rohit Kamboj, Tanu Kamboj, Shailendra Bhatt
Poloxamers, commonly known as Pluronics, are a special family of synthetic tri-block copolymers with a core structure made of hydrophobic poly (propylene oxide) chains sandwiched by two hydrophilic poly (ethylene oxide) chains. It is possible to modify the mechanical, bioactive, and microstructural characteristics of Pluronics to simulate the behavior of different types of tissues. Additionally, they
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Multifunctional Drug Delivery System: Nanosponges Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-11-02 Piyali Barik, Pooja Rani Bhaisal, Sonia Singh
: In recent years, nanotechnology has been the focus of study for the cure of different diseases, among which nanosponge delivery system is one of a kind. Nano sponges are tiny, highly porous, three-dimensional nanostructures with a size range of 250nm-1µm in an amorphous or crystalline structure. Nanosponges usually act as an excipient or carrier of a drug in the different delivery systems. The type
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Double Bubble Electrospinning: Patents and Nanoscale Interface Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-10-25 Muhammad Ali, Ya Li, Ji-Huan He
Background: Bipolymeric nanofibers have gained significant attention in various fields due to their enhanced functionality, improved mechanical properties, and controlled release capabilities. However, the fabrication of these composite fibers with a well-defined polymer-polymer interface remains a challenging task. Methods: The double bubble electrospinning setup was developed and simulated using
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A Comprehensive Review on Recent Advances and Patents of Niosomes Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-10-19 Sushma Verma, Sakshi Saharawat
: Niosomes are novel, self-assembled vesicular carriers that deliver both lipophilic and hydrophilic drugs at the specific site in a targeted way, enhancing bioavailability and extending therapeutic effects. Niosomes are a versatile drug delivery system with a diverse range of applications from gene to brain-targeted delivery and they are more attractive choices than liposomes as they are efficient
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A Short Appraisal of Magnetic Nanoparticles for Breast Cancer: In vitro and In vivo Research Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-22 Simranjeet Kaur, Dilpreet Singh
The increasing incidence of breast cancer and the associated morbidity due to higher metastasis created the urge to develop a nanocarrier that can be used as a potent therapeutic carrier with targeting efficacy. The use of superparamagnetic nanoparticles in breast cancer research and treatment has gained considerable attention in recent years. Magnetic nanoparticles (MNPs) can be used to construct
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Magnetic field modulation effect of photoelectric properties in dye-sensitized solar cells with La0.67(Ca,Ba)0.33MnO3 as counter electrodes Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-18 Guanzhong Huo, Wenqing Lin, Ke Wang, Zhe Pei, Xuan Du, Shuiyuan Chen, Chao Su, Qingying Ye, Guilin Chen
Background: In recent years, many semiconductor materials with unique band structures have been used as Pt counter electrode (CE) substitutes for dye-sensitized solar cells (DSSCs), which makes the photoelectric properties of DSSCs possible to be modulated by electric field, magnetic field, and light field. In this work, La0.67(Ca Ba)0.33MnO3 (LCBMO) thin film is employed to act as CE in DSSCs. Method:
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An Overview of Current Progress and Challenges in Brain Cancer Therapy Using Advanced Nanoparticles Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-13 Mahima Chauhan, Rahul Pratap Singh, Sonali, Ghazala Zia, Saurabh Shekhar, Bhavna Yadav, Vandana Garg, Rohit Dutt
Brain tumors pose significant challenges in terms of complete cure and early-stage prognosis. The complexity of brain tumors, including their location, infiltrative nature, and intricate tumor microenvironment (TME), contributes to the difficulties in achieving a complete cure. The primary objective of brain cancer therapy is to effectively treat brain tumors and improve the patient’s quality of life
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A Critical Appraisal of Functionalized 2-Dimensional Carbon-Based Nanomaterials for Drug Delivery Applications Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-13 Dilpreet Singh, GD Gupta, Nimish Gupta, Princi Verma, Abhisek Dey, Simranjeet Kaur, Akshay Kumar, Namandeep Raj
: The development of an efficient and innovative drug delivery system is essential to improve the pharmacological parameters of the medicinal compound or drug. The technique or manner used to improve the pharmacological parameters plays a crucial role in the delivery system. In the current scenario, various drug delivery systems are available where nanotechnology has firmly established itself in the
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Nano-based therapeutics for Rheumatoid arthritis: Recent patents and development Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-11 Manish Makhija, Deeksha Manchanda, Manu Sharma
: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease marked by inflammation of synovium and generation of autoantibodies. Bone and cartilage are frequently damaged along with weakening of tendons and ligaments resulting in disability. An effective RA treatment needs a multi-disciplinary approach which relies upon pathophysiology that is still partially understood. In RA patients, inflammation
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A systematic review and meta-analysis of the metal nano-particles loaded with herbal drugs moieties against breast cancer Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-11 Suchitra Nishal, Virender Kumar, Parmita Phaugat, Davinder Kumar, Naveen Khatri, Gajendra Singh
Background: Breast cancer is the most prevalent cancer among women. About 685K deaths were globally listed in 2020 by the World Health Organization. Nowadays, scientists prefer to use herbal medicines due to their low toxicity. Herbal medicines are used to overcome the toxicity effects of surgical removal, radio-chemo therapy and medication, which have a lot of risk of damaging the healthy tissues
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An Overview of Metallic Nanoparticles: Classification, Synthesis, Applications, and their Patents Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-08 Sarika Dhir, Shailendra Bhatt, Mahima Chauhan, Vandana Garg, Rohit Dutt, Ravinder Verma
Background: Nanotechnology has gained enormous attention in pharmaceutical research. Nanotechnology is used in the development of nanoparticles with sizes ranging from 1-100nm, with several extraordinary features. Metallic nanoparticles (MNPs) are used in various areas, such as molecular biology, biosensors, bio imaging, biomedical devices, diagnosis, pharmaceuticals, etc., for their specific applications
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Exploring the Prospective of Curcumin-loaded Nanomedicine in Brain Cancer Therapy: An Overview of Recent Updates and Patented Nanoformulations Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-07 Ravinder Verma, Lakshita Rao, Diksha Nagpal, Manish Yadav, Manish Kumar, Vineet Mittal, Deepak Kaushik
Cancer is a complex, one of the fatal non-communicable diseases, and its treatment has enormous challenges, with variable efficacy of traditional anti-cancer agents. By 2025, it is expected that 420 million additional cases of cancer will be diagnosed yearly. However, among various types of cancer, brain cancer treatment is most difficult due to the presence of blood-brain barriers. Nowadays, phytoconstituents
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Dendrimers: Patents for Alzheimer’s disease Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-09-01 Shubhrat Maheshwari, Aditya Singh
: Cells and nervous system connections that are crucial for movement, coordination, strength, sensation, and thought are gradually damaged in neurodegenerative illnesses. Amyloid beta (Aβ)-accumulating macromolecules in the brain are the primary cause of the disease's chronic symptoms, according to analysis carried out during the last 20 years. Plaques and clumps of amyloid- build up in the brain,
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A comprehensive update on Nanotechnology in functional food developments: Recent updates, challenges, and future perspectives Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-29 Sumel Ashique, Shubneesh Kumar, Ekta Sirohi, Afzal Hussain, Arshad Farid, Md. Faiyazuddin, Neeraj Mishra, Ashish Garg
: The food business makes extensive use of lipophilic bioactive substances derived from plants, such as phytosterols, antimicrobials, antioxidants, ω3 fatty acids, tastes, and countless other constituennts. The preponderance of these bioactive substances, nevertheless, is just about unsolvable in hydric solution and unbalanced at a particular eco-friendly provocation, such as sunlight, temperature
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Nano - Based Therapeutic Strategies in Management of Rheumatoid Arthritis Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-23 Parijat Pandey, Gunjan Nautiyal, Shiv Kant Sharma, Dhirender Kaushik
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease, progressively distinctive via cartilage destruction, auto-antibody production, severe joint pain, and synovial inflammation. Nanotechnology represents as one of the utmost promising scientific technologies of the 21st century. It exhibits remarkable potential in the field of medicine, including imaging techniques and diagnostic
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Parametric Analysis of Indium Gallium Arsenide Wafer-based Thin Body (5 nm) Double-gate MOSFETs for Hybrid RF Applications Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-22 Pattunnarajam Paramasivam, Naveenbalaji Gowthaman, Viranjay. M. Srivastava
Introduction: The electrical behavior of a high-performance Indium Gallium Arsenide (In- GaAs) wafer-based n-type Double-Gate (DG) MOSFET with a gate length (LG1= LG2) of 2 nm was analyzed. The relationship of channel length, gate length, top and bottom gate oxide layer thickness, a gate oxide material, and the rectangular wafer with upgraded structural characteristics and the parameters, such as switch
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Expression and clinical significance of Cat B and sICAM-1 in the GCF of patients with peri-implantitis Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-18 Qinglian Wang, Jichao Lin, Yanjun Lin, Youcheng Yu
Background: Peri-implantitis is an irreversible disease occurring in the tissues surrounding dental implants, and it is characterized by decreased osseointegration, progressive bone loss, bone resorption, and increased pocket formation and purulence. Objective: This study was conducted to elucidate the expression and clinical significance of Cat B and sICAM-1 in the gingival crevicular fluid (GCF)
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Croton cajucara: Patents and Nanotechnological Advances Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-17 Daniel Dias Rufino Arcanjo, Lais Rocha Lima, Francisco Lopes da Silva Júnior, Maria Aparecida Medeiros Maciel
: Croton cajucara Benth showed several pharmacological properties such as: anti-inflammatory, antinociceptive hypoglycemic, lipid-lowering, antiulcer, antiestrogenic, antitumor, antigenotoxic, antimutagenic, and cardiovascular. The 19-nor-clerodane diterpene trans-dehydrocrotonin (t-DCTN or DCTN) is the major bioactive constituent extracted from the bark of this Croton. Patents for Croton cajucara
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A Comprehensive Review on Prospects of Polymeric Nanoparticles for Treatment of Diabetes Mellitus: Receptors-Ligands, In vitro & In vivo Studies Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-03 Arinjay Jain, Shilpa Dawre
: As per International Diabetes Federation Report 2022, worldwide diabetes mellitus (DM) caused 6.7M moralities and ~537M adults suffering from diabetes mellitus. It is a chronic condition due to β-cell destruction or insulin resistance that leads to insulin deficiency. This review discusses Type-1 DM and Type-2 DM pathophysiology in detail, with challenges in management and treatment. The toxicity
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Recent Advancements in Novel Formulations of Anti-psoriatic Agents for Effective Delivery: Clinical Importance and Patent Survey Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-08-03 Nikhil Dadwal, Balak Das Kurmi, Dilpreet Singh, Amrinder Singh
Background: An autoimmune-mediated dermatological ailment featuring recurrent episodes is acknowledged as psoriasis. Around the world, 2–3% of people suffer from this autoimmune skin condition. Objectives: The primary goal of the current review is to analyse and determine the effectiveness of conventional and emerging nano technological strategies to alleviate psoriasis and discuss future perspectives
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Nanocomposite hydrogels: an optimistic insight towards the treatments of ocular disorders Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-31 Gayatri Patel, Shailvi shah, Riya Patel
Background: The distinct anatomy and physiology of the eye represent it as a specialized organ. The noumenal physiological barriers, whose prominent role is to prevent the entrance of extracellular substances, reduce the bioavailability of medicines taken locally. Nanocarriers offer many advantages, such as site-specific drug delivery, reduced dose-related side effects, more drug loading capacity,
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Untangling breast cancer: Trailing towards nanoformulations-based drug development Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-31 Deepak Kaushik, Ravinder Verma, Kuldeep Kumar, Shailendra Bhatt, Manish Yadav, Manish Kumar, Priti Tagde, P.S. Rajinikanth, Abhishek Tiwari, Varsha Tiwari, Diksha Nagpal, Vineet Mittal
: All over the world, cancer death and prevalence are increasing. Breast cancer (BC) is the major cause of cancer mortality (15%) which makes it the most common cancer in women. BC is defined as the furious progression and quick division of breast cells. Novel nanotechnology-based approaches helped in improving survival rate, metastatic BC is still facing obstacles to treat with an expected overall
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Recent progression in nanocarrier based techniques to address fungal infections and patent status in drug development process Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-27 Amrinder Singh, Ravi Pratap Singh, Raj Kumar Narang
: Fungal infections are becoming one of the most common diseases in recent years, especially when it comes about dealing skin infections. Different drugs are available commercially with antifungal activity for topical application and are effective for treatment of mild to moderate fungal infections. However they lack dermal bioavailability due to their poor penetrability, and less retention at the
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The Emergence of Nanotechnology in the Prognosis and Treatment of Myocardial Infarctions Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-25 Shivkant Sharma, Isha Sharma, Shivani Bhardwaj, Ritu Karwasra, Dhirender Kaushik
: Myocardial infarction (MI), commonly known as a heart attack, is a critical cardiovascular condition associated with high morbidity and mortality rates worldwide. Despite significant advancements in traditional treatment modalities, there remains a need for innovative approaches to improve the prognosis and treatment outcomes of MI. The emergence of nanotechnology has provided a promising avenue
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Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-19 Neha Minocha, Astha Singh, Aakriti Patel, Hema Chaudhary, Kiran Yadav
Background: Theranostics is a method that focuses on providing patient-centred care and is evolving as a targeted, safe, and effective pharmacotherapy. Nanotheranostics combines diagnosis and therapeutic modalities that bridge traditional treatment and personalised medicine. Theranostics provides novel ideas for nanotechnology. This review describes the current state of nanotechnology-based therapies
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Mapping the Nanotechnology Patent Landscape in the Field of Cancer Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-07-19 Haoyu Sun, Tong Wu, Xinrui Liu, Huanzhang Xia, Hongmei Yuan
Background: Currently, cancer is still a significant disease that seriously endangers human health. Therefore, advanced diagnostic technology and treatment protocols are urgently needed. The rapid development of nanotechnology is expected to provide new ideas for cancer diagnosis and treatment. Objective: The research aims to comprehensively demonstrate the hotspots of nanotechnology applications in
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Optimization of Double-Gate Carbon Nanotube FET Characteristics for Short Channel Devices Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-23 Vijai M. Moorthy, R. Venkatesan, Viranjay M. Srivastava
Introduction: Transistors are the fundamental electronic component integrated into electronic devices' chips Carbon Nano Tube (CNT) based field. Method: Effect Transistor (FET) is a promising component for next-generation transistor technologies; as it has high carrier mobility, device stability, and mechanical flexibility. Nevertheless, some shortcomings in the CNT FET's design prevent it from providing
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Two-dimensional MXene Nanomaterials: Preparation, Structure Modulation and the Applications in Electrochemical Energy Storage Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-22 Yingchun Chen, Bei Yu, Lingling Peng
Background: MXenes have attracted intensive attention owing to their unique twodimensional (2D) layered structure, high specific surface area, excellent conductivity, superior surface hydrophilicity, and chemical stability. In recent years, selective etching of the A element layers from MAX phases by fluorine-containing etchants (HF, LiF-HCl, etc) is a common method to prepare multilayered MXene nanomaterials
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Nanocrystal Materials for Resistive Memory and Artificial Synapses: Progress and Prospects Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-22 Yingchun Chen, Dunkui Chen, Chi Zhang, Xian Zhang
Background: Resistive random-access memory (RRAM) is considered to be the most promising next-generation non-volatile memory because of its low cost, low energy consumption, and excellent data storage characteristics. However, the on/off (SET/RESET) voltages of RRAM are too random to replace the traditional memory. Nanocrystals (NCs) offer an appealing option for these applications since they combine
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Applications of Silver Nanoparticles in Patent Research Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-21 Ana Paula G.B. Azevedo, Nathalia Müller, Celso Sant´Anna
Background: Silver nanoparticles (AgNPs) have been widely applied in research and industrial fields, finding applications in nanomedicine, drug delivery, biomedical devices, electronics, the energy sector, and environmental protection. Patents provide information on the industrial viability of product technologies, and the number of patent documents provides an estimate of the evolution of a specific
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Investigations on Cylindrical Surrounding Double-gate (CSDG) Mosfet using ALXGA1-XAS/INP: PT with LA2O3Oxide Layer for Fabrication Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-19 Naveenbalaji Gowthaman, Viranjay M. Srivastava
Background/Introduction: The Cylindrical Surrounding Double-Gate MOSFET has been designed using Aluminium Gallium Arsenide in its arbitrary alloy form alongside Indium Phosphide with Lanthanum Dioxide as a high-ƙ dielectric material. Objective: To conduct research on the novel application of AlxGa1-xAs/InP: Pt with La2O3 oxide layer in the fabrication of Cylindrical Surrounding Double-gate (CSDG) MOSFET
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Modeling, Optimization, and Simulation of Nanomaterials-Based Organic Thin Film Transistor for Future Use in pH Sensing Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-19 Vijai Meyyappan Moorthy, Viranjay Srivastava Mohan
Introduction: Applications of Organic Thin Film Transistor (OTFT) range from flexible screens to disposable sensors, making them a prominent research issue in recent decades. A very accurate and exact pH sensing determination, including biosensors, is essential for these sensors. Methods: In this present research work, authors have proposed a nanomaterial-based OTFT for future pH monitoring and other
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In-vivo pharmacokinetic assessment and In-vitro characterization of strategically optimized Perphenazine-loaded nanostructured lipid carriers for nose-to-brain Targeting Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-14 Yogeeta O. Agrawal, Tulshidas S. Patil, Kiran D. Patil, Nayan A. Gujarathi, Amit Gangwal, Sameer N. Goyal
Background: Perphenazine (PPZ) is a prevalent antipsychotic medication used to treat schizophrenia. After oral treatment, however, it shows substantial first-pass metabolism and decreased bioavailability. Objective: The goal of this research was to incorporate PPZ into nanostructured lipid carriers and thereby improve its bioavailability and brain targeting (PPZ-NLCs). Method: PPZ-NLCs were formulated
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Emerging Nanotechnology-based Therapeutics: A New Insight into Promising Drug Delivery System for Lung Cancer Therapy Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-14 Ravinder Verma, Lakshita Rao, Diksha Nagpal, Manish Yadav, Vivek Kumar, Vikram Kumar, Harish Kumar, Jatin Parashar, Nitin Bansal, Manish Kumar, Parijat Pandey, Vineet Mittal, Deepak Kaushik
Background: Lung cancer is a foremost global health issue due to its poor diagnosis. The advancement of novel drug delivery systems and medical devices will aid its therapy. Objective: In this review, the authors thoroughly introduce the ideas and methods for improving nanomedicine-based approaches for lung cancer therapy. This article provides mechanistic insight into various novel drug delivery systems
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Nanoneuroscience: Cutting-edge Approach for Disease Management Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-13 Sakshi Malhotra, Neha Jain, Jatin Rathee, Shreya Kaul, Upendra Nagaich, Manisha Pandey, Bapi Gorain, Gaurav Gupta
Neurological disorders (ND) have affected a major part of our society and have been a challenge for medical and biosciences for decades. However, many of these disorders haven't responded well to currently established treatment approaches. The fact that many active pharmaceutical ingredients can't get to their specified action site inside the body is one of the main reasons for this failure. Extracellular
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Preclinical Safety Assessment of Lepidium sativum L. Seed Extract and its Nanoparticles via Acute and Subacute Oral Administration Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-06-06 Asad Ahmad, Anuradha Mishra, Rabia Nabi, Iffat Ahmad
Background: Lepidium sativum (LS) seed extract has various pharmacological properties, such as antioxidant, hepatoprotective, and anticancer activities. However, the translation of L. sativum seed extract to the clinical phase is still tedious due to its bioavailability and stability issues. This problem can be solved by encapsulating it in a nanodelivery system to improve its therapeutic potency.
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Research and Progress of Inorganic Infrared Electrochromic Materials and Devices Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-05-19 Xinglin Li, Rihui Yao, Muyun Li, Chenxiao Guo, Dongxiang Luo, Jinyao Zhong, Zhuohui Xu, Honglong Ning, Junbiao Peng
Background: Electrochromic materials can dynamically change their optical properties (such as transmittance, absorbance, and reflectance.) under the action of an applied voltage, and their research and application in the visible band have been widely concerned. In recent years, with the continuous development of electrochromic technology, the related research has been gradually extended to the infrared
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A Complete Sojourn of Current Trends in Gastro-retentive Drug Delivery System: Recent Advances and Patent Survey Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-05-10 Abhisek Dey, Amrinder Singh, Balak Das Kurmi, Dilpreet Singh
The current work aims to provide a complete sojourn on gastro-retentive drug delivery system (GRDDS) along with formulation methods, polymer selection, and in vitro/ in vivo challenges with finished dosage forms. Ideally, a biopharmaceutical-hindered drug has a rapid clearance and erratic bioavailability due to its low aqueous solubility and permeability. Additionally, it also suffers from high first-pass
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Synthesis and Evaluation of Bone Targeting PLGA Nanoparticles Loaded with Components of Traditional Chinese Medicine Formulas Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-05-03 Zehao Zhao, Yanling Deng, Yu Deng, Zhuojun Chen, Zhikun Zhou
Background: Targeted nanoparticles’ preparation can enhance local drug concentration and reduce the side effects of drugs in non-targeted organs. At present, many patents have been applied for in the field of bone-targeted nanoparticles’ preparations. They play an important role in the treatment and diagnosis of diseases. In this experiment, nanoparticles with bone targeting function were prepared
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Role of Apoptotic-targeted Phytoconstitutent-loaded Antipsoriatic Nanobiocomposites Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-02-27 Pankaj Singh Patel, Rajnish Srivastava, Sunita Panchawat
Psoriasis is an inflammatory and proliferative autoimmune dermatological disorder. It is a skin ailment that is defined by particular, drab-red or peach-pink stiff areas with silvery scales patches. Other typical characteristics include the proliferation of epidermal layer, aberrant keratinization, hyperkeratosis, increased micro capillary vascularization, and infiltration of inflammatory mediator
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Nanostructured Lipid Carriers (NLCs) as Effective Drug Delivery Systems: Methods of Preparation and their Therapeutic Applications Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2023-02-21 Hind M. Alatawi, Shemah S. Alhwiti, Khwlah A. Alsharif, Shyma S. Albalawi, Shroug M. Abusaleh, Ghada K. Sror, Mona Qushawy
One of the drug delivery technologies is nanostructured lipid carriers (NLCs), which improve drug permeability and thus bioavailability. NLCs are nanoparticles made from a lipid matrix made up of a mixture of solid and liquid lipids. The inclusion of liquid lipids is useful in lowering the ordered structure of solid lipids, increasing nanoparticle loading capacity, and drug entrapment efficiency within
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Investigation of Electromagnetic Wave Absorption Properties of Ni-Co and MWCNT Nanocomposites Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-12-21 Majid Ebrahimzadeh, Abdolrasoul Gharaati, Alireza Jangjoo, Hamed Rezazadeh
Background: In recent years, severe electromagnetic interference among electronic devices has been caused by the unprecedented growth of communication systems. Therefore, microwave absorbing materials are required to relieve these problems by absorbing the unwanted microwave. In the design of microwave absorbers, magnetic nanomaterials have to be used as fine particles dispersed in an insulating matrix
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Design Optimization and Evaluation of Solid Lipid Nanoparticles of Azelnidipine for the Treatment of Hypertension Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-11-11 Tejas Dugad, Abhishek Kanugo
Background: Solid lipid nanoparticles (SLN) are the most promising lipid-based drug delivery to enhance poorly water-soluble molecules' solubility, bioavailability, and therapeutic efficacy. Azelnidipine (AZN) is a calcium channel blocker widely recommended for treating high blood pressure, but its activity is restricted due to high lipophilicity and poor solubility in the GIT. The current research
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Wave-Assisted Techniques, a Greener and Quicker Alternative to Synthesis of Cyclodextrin-Based Nanosponges: A Review Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-10-20 Pankaj Wadhwa, Mohit Vij, Neha Dand
The ever-increasing applications of cyclodextrin and cyclodextrin-based nanosponges in formulation development has gained much attention from researchers towards needed research in this arena. Nanosponges are three-dimensional nanoporous versatile carriers in the pharmaceutical research field because of their capability to encapsulate lipophilic and hydrophilic drugs both in their crystalline structure
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Nanosponges- Versatile Platform as Drug Carrier Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-10-05 Ujjwala Kandekar, Rohini Pujari, Neha Munot, Trushal Chorge, Krishnakumar Lone, Pallavi Kamble, Khandelwal Kishanchand
Background: Recently, nano-drug delivery systems have become an integral part of the most novel drug delivery systems and have gained considerable importance owing to various advantages such as carriers for poorly soluble drugs, targeting molecules at the desired site, protection from degradation etc. Objective: One of the most studied areas of nanotechnology is nanosponges. The objective of this review
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Formulation and Characterization of Self-Microemulsifying Drug Delivery System (SMEDDS) of Sertraline Hydrochloride Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-10-05 Sanjay Sharma, Abhishek Kanugo, Tejvir Kaur, Deepak Choudhary
Background: Sertraline hydrochloride is the most widely used selective serotonin reuptake inhibitor (SSRI) for treating several depressive disorders. The applicability of Sertraline hydrochloride is limited due to the extensive metabolism and poor oral bioavailability of 44%. Objective: The current research focused on improving the solubility and oral bioavailability of Sertraline in the form of microemulsion
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Hybrid Nanocarriers for Neurological Disorders: Diagnostic & Therapeutic Approach Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-09-23 Anuradha Mishra, Rabiya Ahsan, Anas Islam, Rohit kumar Tiwari, Pragyandip P. Dash
Background: Around 1.5 billion people in the world are affected by complex neurological disorders, and the figure is increasing alarmingly due to unsatisfactory clinical outcomes. To date, no conventional formulation can show a promising effect on the control or prevention of neurodegeneration. However, Nano delivery tools have shown better penetration and profound action on the targeted area of the
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Green Synthesis of Silver Nanoparticles of Vernonia cinerea Leaf Extract and their In vitro Cytotoxicity Activity Against Neuroblastoma SHSY-5Y Cell Lines, Antimicrobial and Antioxidant Studies Recent Pat. Nanotechnol. (IF 2.0) Pub Date : 2022-09-23 Narahari N. Palei, S. Navaneetha Krishnan, R. Jayaraman, S. Hemanth Reddy, Anna Balaji, Malay K. Samanta, Bibhash C. Mohanta
Background: Green syntheses of silver nanoparticles using plant extracts have potential anti- cancer, antimicrobial, and antioxidant properties, among other aspects. The aim of the present study was to synthesize silver nanoparticles (AgNPs) using Vernonia cinerea plant extract. Methods: The AgNPs were successfully prepared and characterized using UV-Vis Spectrophotometer, particle size, Zeta potential