In the published article, one of the author names was spelled incorrectly.

AbstractAn expeditious, metal-free protocol has been demonstrated for the synthesis of isoxazolone derivatives using domino multi-component strategy. The envisaged methodology involves the L-valine promoted three-component cyclo-condensation reaction of alkylacetoacetates, hydroxylamine hydrochloride and aldehydes in ethanol under reflux. The reaction proceeded to deliver the desired products in good

AbstractSome of the chalcones and flavones are very efficient to facilitate the signal of death to the lung cancer cell through blocking the active site BH3 of Bcl-2 proteins. We designed a number of novel chalcones and flavones targeting the active site of the protein. Docking study showed that the designed compounds were very efficient as the reported compounds. We synthesized and characterized some

AbstractAmyloids, a well-ordered β-sheet-enriched structural network, can be broadly defined as insoluble protein aggregates that are linked to a wide variety of diseases including systemic amyloidosis and some neurodegenerative disorders. Ferulic acid (FA), a phenolic acid, abundant in antioxidant and efficient pharmaceutical has beneficial effects against several ailments. Based on this, we have

AbstractIn this work, we evaluated the antiproliferative and anti-inflammatory activities of two diosgenin prodrugs. The prodrugs were obtained by esterification of diosgenin at position 3 with 4-oxo-4-(prop-2-yn-1-yloxy)butanoic acid followed by click reaction on terminal alkyne with 3-azidopropan-1-ol N-alkylated dendrons, resulting in a prodrug with methyl ester end-groups and a derivative with

AbstractA polyelectrolyte complex (PEC) made up of poly(di-allyl di-methylammonium chloride) and poly(styrene sulphonate) polyelectrolytes has been synthesised and used for the immobilisation of phosphomolybdate (PMo), \( \left[ {{\text{PMo}}_{12} {\text{O}}_{40} } \right]^{ 3- } \) nanoclusters. The material is characterised by FTIR, powder XRD, SEM, TEM and UV-Visible DRS spectroscopy. It was found

AbstractThe novel energetic triblock copolymer of polypropylene glycol-glycidyl azide polymer-polypropylene glycol (PPG-GAP-PPG) (\( \bar{M}_{\text{n}} \) = 1639 g·mol−1) was synthesized and optimized by cationic ring-opening polymerization of propylene oxide using low-molecular-weight glycidyl azide polymer (GAP) (\( \bar{M}_{\text{n}} \) =1127 g·mol−1) as the initiator and boron trifluoride etherate

AbstractThis report describes the synthesis and structural characterizations of three new complexes; [Na3Fe2(bbp)(Hbbp)(CN)6(H2O)9]·4H2O (1), (Bu4N)[Fe(bbp)2]·3CH3OH·2H2O (2), and a cyano-bridged dinuclear copper(II) complex, [Cu2(tren)2(CN)][Fe(bbp)2]3· 6CH3OH·4H2O (3), where H2bbp = bis(2-benzimidazolyl)pyridine and tren = tris(2-aminoethyl)amine. X-ray crystallography reveals that the geometry of

AbstractHere reports a hollow cube NiCo2S4 nanomaterial, which was prepared via facile hydroxylation and sulfuration steps using the self-prepared ZIF-67 as a precursor. This kind of NiCo2S4 as an electrode material for supercapacitor presents a specific capacitance high up to 1350 F g-1 at 1 A g-1 due to the contribution of pseudocapacitance. Particularly, the hybrid supercapacitor PC//NiCo2S4, assembled

AbstractNew steroidal D-homo androstane derivatives with 5β,6β-epoxy-3,16-dicarbonyl, 6α- and 6β-hydroxy-3,16-dicarbonyl and 3β,5α-dihydroxy-6,16-dicarbonyl moieties were synthesized and confirmed by NMR spectroscopy. Novel and starting compounds were evaluated for their potential cytotoxicity in vitro against seven human cancer cell lines (MCF-7, MDA-MB-231, PC3, HeLa, HT-29, A549 and CEM) and one

AbstractThe quinazoline-2,4-diones scaffold is found in bioactive compounds, commercial drugs and exhibit important biological activities. However, their antidiabetic activity is rarely explored. For this purpose, an easy one-pot three-components and straightforward synthesis of 3-substituted quinazoline-2,4-diones was designed, in both, the catalyst- and solvent-free conditions under microwave irradiation

AbstractThe metal–organic frameworks (MOFs) or porous coordination polymers (PCPs) are a class of porous, crystalline material with numerous possibilities of real-world applications including storage, separation, catalysis, sensing etc. The possibility of intrinsic crystallinity and virtually infinite metal/metal-oxo node and organic linker combination make it a perfect material for photophysical studies