Oxidation of diethyl disulfide with atmospheric oxygen at 363 К in the presence of 1,3-dimethylimidazolium dimethyl phosphate is described. On the basis of the 1Н, 31Р, and 13С NMR data, it is shown that oxidation of diethyl disulfide results in ethyl sulfonates. Formation of ethyl alcohol, which is a product of a side reaction of ethyl sulfonate hydrolysis, probably, catalyzed by the 1,3-dimethylimidazolium

Methods for the synthesis of ceramic-forming organoelement poly(oligo)mers, metallocarbosilanes and organoelement oxanealuminoxanes, as precursors of components (matrices, coatings, fibers, etc.) for the development of high-temperature, high-strength, and oxidation-resistant nanostructured carbide and oxide ceramic composites are presented.

Eight complex compounds of MnII, FeII, CoII, NiII and CuII with 2,4,6-trihydroxy benzoic acid and 3,4,5-trihydroxybenzoic acid were synthesized in a crystalline form. Nanosized metal oxide particles obtained by thermal decomposition of the complexes were studied by X-ray powder dif raction analysis and electron microscopy.

The effect of cucurbit[7]uril (CB7) on photo induced transformations of cationic dye 3,3′-diethylthiacarbocyanine iodide (Dye+) in water in the presence of 9-anthracene carb oxylic acid as photosensitizer was studied by nanosecond laser photolysis. Sensitized photoexcitation of Dye+ leads to population of the triplet level of the dye. The photoisomerization proceeds via the formation of an intermediate

In order to study the mechanism of interaction of 4-(2-thiazolylazo)catechol with natural sulfides specifically with sulfides of various metals, the complexation of this azo compound with copper(II), cobalt(II), nickel(II), and zinc(II) ions in aqueous solutions was investigated. The reagent forms positively charged complexes with metal ions in the range of pH = 5.8—11.1. Their composition and structure

A new method for recycling of polyethylene terephthalate (PET) wastes, which is based on their processing under the action of a nitrating atmosphere and a subsequent utilization of the conversion products, is considered. It is shown that the exposure of PET samples to an NOx—H2O (steam)—air atmosphere obtained by vaporization of 12 A/TTNO3 at 403-463 K for 5-24 h, dissolution of the conversion products

The review presents a systematic overview of the methods for the synthesis of benzimidazoles with a fluorinated benzene ring and considers applications of these compounds in practice.

2-[4-(Het)aryl-2-oxopyrrolidin-1-yl]acetohydrazides, structural analogs of piracetam, were synthesized by the condensation of 2-[4-(het)aryl-2-oxopyrrolidin-1-yl]acetates with hydrazine hydrate and phenylhydrazine. New [N′-alkyl(hetaryl)idene]-4-(het)aryl-2-oxopyrrolidin-1-ylacetohydrazides were synthesized by the reaction of 2-[4-(het)aryl-2-oxopyrrolidin-1-yl]-acetohydrazides with aromatic aldehydes

For a model series of nitro aromatic compounds comprising mono-, di- and trinitrotoluenes, and dinitrobenzene, using the same commercial experimental set up consisting of gas chromato-graphy/mass spectrometry (GC/MS) instrument equipped with a quadrupole analyzer, the two types of mass spectra were recorded, of positive ions (in the conventional, standard mode of electron ionization at 70 eV) and of

The crystallophores of the composition Sr2La8(1x-y)ErxYbyGe6O26 (x = 0.01, 0.05, 0.075, 0.1, 0.15) were synthesized. Nanophosphores in the amorphous state were obtained for the first time by the method of pulsed electron beam evaporation using a phosphor of the composition Sr2La7.85Er0.075Yb0.075Ge6O26 with the structure of oxyapatites as a target. DSC-TGA analysis was performed to determine the temperature

A technique of preparative adsorption chromatography, according to which the separation of substances is determined by the effect of kinetic selectivity of sorption (KSS), is discussed. Unlike traditional chromatography methods, in which separation is determined by the difference in the binding strength of the separated components (distribution coefficients), in kinetically selective chromatography

A technique for the synthesis of bismuth orthoferrite nanopowder doped with cobalt ions activated using microwave radiation is proposed. Exposure to microwave radiation followed by ultrasonic treatment of the synthesized BiFeO3 samples using sodium hydroxide as a precipitant makes it possible to obtain spherical BiCoxFe1-xO3 particles with a narrow particle-size distribution in the range of 35–60 nm

The Ritter-type reaction of alkyl perchlorates with nitriles of various structures was systematically studied. The reaction has a wide scope and proceeds under extremely mild conditions without any catalysts or special activation of reagents. A structural diversity of the obtained by the Ritter-type reaction N-alkyl amides bearing small ring, double bonds, additional functional groups, aromatic and

The hydrated acid hexamolybdocobaltate(III) complex with the amino acid glycine of composition (H3O)3[CoMo6O18(OH)6]•(H3NCH2COO)2(H2O)5 was synthesized. The structure of the new complex was established by single-crystal X-ray diff raction, powder X-ray diff raction, IR and NMR spectroscopy.

The key options for the synthesis of functionalized pillar[5]arenes and their applications in electrochemical sensors and biosensors are considered. Examples of using the macrocycle as an electron transfer mediator, a reactant for the formation of host—guest complexes, and a carrier of biochemical receptors are given. Details of behavior and ways of inclusion of pillararenes into the surface layer

Composite materials (CMs) were synthesized on the basis of nanoporous silicate glasses (PGs) with small additives of P2O5 and fluoride ions doped by silver bromide in the presence or in the absence of cerium or erbium. The obtained CMs were characterized by a complex of methods (X-ray powder diffraction (XRD) technique, energy-dispersive X-ray spectroscopy, and UV-Vis-NIR spectroscopy). According to

Thermodynamic characteristics of the adsorption of benzene and its derivatives on the surface of a porous graphite-like Hypercarb adsorbent from binary polar eluents have been experimentally determined under the conditions of equilibrium HPLC at various temperatures. The retention on Hypercarb columns is generally maintained by non-specific intermolecular interactions with the flat graphite-like surface

A method for the synthesis of metal oxide precursors based on the electrogeneration of reagents in a coaxial electrochemical reactor without a membrane with electrodes substantially different in the surface area was proposed. The electrogeneration is accompanied by the subsequent hydrolysis of the products, the formation of primary particles due to the polycondensation of aquahydroxo complexes, and

New trimethylhydrometallatranes, tris(2-hydroxypropyl)amine complexes with NiII, ZnII, CuII, and CoII salts of biologically active carboxylic acids (benzoic, cinnamic, salicylic, succinic), were synthesized. The structure of the tris(2-hydroxypropyl)amine complex with nickel(II) cinnamate was determined by single-crystal X-ray diff raction. Thermal stability of the synthesized tris(2-hydroxypropyl)amine

The treatment of 7-amino-8-bromo-3-tert-butylpyrazolo[5,1-c][1,2,4]triazin-4(6H)-one with an excess of NaH in THF and AlkLi (Alk = Bun, But) at -97 °C produced disodium (8-lithio-3-tert-butyl-4-oxopyrazolo[5,1-c][1,2,4]triazin-1-id-7-yl)amide unstable under ambient conditions. The chemical properties of the newly synthesized compound were studied. The electrophilic attack occurs at the N(1), C(7)—N

A convenient method for the synthesis previously unknown hydroxy-containing aryl(hetaryl)-ethenes (terarylenes) with a pyrazole bridge was elaborated, which is based on the reaction of hydrazines with the products of condensation of allomaltol with arylglyoxals. Two isomeric pyrazoles can be formed depending on the nature of substituents in the hydrazine molecule. The protocols for identification of

Phase equilibria in the mixtures of polyvinyl alcohol (PVA) and chitosan were revealed. Structures of the phases were identified. The temperature and concentration dependences for the chitosan—PVA and chitosan—PVA—water systems were determined. The phase state diagram was built. It is shown that the polymer mixtures are characterized by a complex supramolecular organization, which corresponds to their

At heating of 2-(2-azido-3,5-dinitrophenyl)-2H-[1,2,3]triazolo[4,5-e][1,2,3,4]tetrazine 4,6-dioxide in toluene at 110 °C, the azido group interacts mainly with the neighboring nitro group and to a lesser extent with the neighboring 1,2,3-triazole ring, resulting in 2-(6-nitrobenzofuroxan-4-yl)-2H-[1,2,3]triazolo[4,5-e][1,2,3,4]tetrazine 4,6-dioxide (2) in 68% yield, as well as 8,10-dinitro-5,11-dehydro-5H

A simple technique for introducing iron hydroxide into a highly porous polystyrene matrix is proposed. The resulting composite sorbent showed a high ability to purify air by removing hydrogen sulfide, bad-smelling, and toxic products of decay of natural remains, such as putres-cine, cadaverine, indole, and skatol, as well as organic solvents, such as methanol and benzene.

A single crystal of indium(iii) acetylacetonate (In(acac)3) was obtained by alternating-current electrochemical dissolution of indium metal in the presence of acetylacetone in acetonitrile. The structure of the obtained product was confirmed by X-ray diffraction.

Reactions of 3-tert-butyl- or 3,4-di-tert-butyl-substituted 8-methylpyrazolo[5,1-c][1,2,4]-triazines with trifluoroacetic anhydride afforded 1-(2,2,2-trifluoroacetyl)-1,4-dihydropyrazolo-[5,1-c][1,2,4]triazin-4-yl 2,2,2-trifluoroacetates. The treatment with H2X and RXH (X = O or S; R = Me or Et) of covalent trifluoroacetate that does not contain the But group at the C(4) atom allowed us to synthesize

Catalytic allylation of norbornadiene in the presence of Ni0 phosphite complexes resulting in 3-methylenetricyclo[4.2.1.02,5]non-7-ene was studied within the framework of the density functional theory using the PBE functional and the L11, L2, and L3 basis sets. According to calculations, the formation of the first C-C bond more likely proceeds involving the η3-allyl rather than η1-allyl ligand. The

New 2-amino- and 2-hydroxymethylbenzimidazoles were synthesized and used to prepare the previously unknown 1,2,3-tri- and 1,2,3,5-tetrasubstituted benzimidazolium bromides with a biphenyl-containing substituent at the imidazole nitrogen atom. In some cases, these bromides exhibit activity against targets associated with diabetes mellitus. These compounds are strong protein tyrosine phosphatase 1B (PTP1B)

The dependence of lead silicate glass color, applied using copper(ii) ions, on lead content in the glass, the nature of the alkali metal, and copper content was studied. It was shown that the principal contribution to the color is made by the shift of the fundamental absorption edge, which correlates with the amount of lead and copper ions. According to EPR results for glasses with the studied compositions

The sodium and bis(arene)chromium salts of monosubstituted hydrofullerides, containing bis(3,4-dimethoxyphenyl)phenylmethane, 2,6-bis(4-methoxyphenyl)-4-phenylpyridine, 15-crown-5, N-ethyl-N-phenylbenzamide moieties, were synthesized and theirs NIR spectrum were investigated.

Phase equilibria in the water-ethoxylated nonylphenol (neonol AF 9–12)-sodium sulfate system were studied at 25 °C using isothermal titration and isothermal section methods. It was found that neonol AF 9–12 exerts a dehydrating effect on sodium sulfate. The optimum extraction parameters were determined for the studied system: the neonol AF 9–12: Na2SO4 weight ratio is 1:3, and the water weight fraction

New high-molecular-weight contrast agents based on polyamidoamine (PAMAM) dendrimers for targeted imaging of malignant tumors characterized by overexpression of human epidermal growth factor receptor (EGFR) and human alpha-fetoprotein receptor (RECAF) were designed. Conjugates of second (G2) and third (G3) generation polyamidoamine dendrimers with 1,4,7,10-tetraazocyclodecane-1,4,7,10-tetraacetic acid

New polymer nanocomposites containing silver nanoparticles, stabilized by hydrophilic copolymers of 1-vinyl-1,2,4-triazole with vinylsulfonic acid sodium salt of different composition, were synthesized. Nanocomposites formation was carried out by the method of chemical reduction of silver ions by sodium borohydride in an aqueous medium in the presence of co-polymer. It was established according to

A combined catalytic system composed of catalysts with different functions was prepared. The catalyst for the synthesis of lower olefins based on is H-ZSM-5 zeolite modified with Mg, was mixed with the catalyst for alkylation of isobutane by olefins based on H-Y zeolite modified with La and Pd. In the presence of the combined system, liquid branched hydrocarbons were synthesized from dimethyl ether

Hydroformylation reactions and related tandem reactions (hydroformylation—hydrogenation, hydroaminomethylation) proceeding without introduction of syngas were considered. Reaction systems, in which other gases or liquid-dissolved reagents were used as a formyl group source, were described and systematized.

Polymerization of methyl methacrylate in the presence of 2,5-di-tert-butyl-p-benzoquinone is a combination of two processes: inhibited and controlled radical polymerization. The adduct of chain propagation radicals and p-quinone formed due to the inhibited polymerization is a macroinitiator of controlled radical polymerization. The fraction of the pseudo-living process is determined by the concentration

The results of the study of the PbSe—AgSbSe2 system by measuring the emf of concentration chains with respect to PbSe in a temperature range of 300–450 K are presented. The formation in the system of a wide (37–100 mol.% AgSbSe2) region of solid solutions based on AgSbSe2 is shown. The partial thermodynamic functions of PbSe and lead in the alloys are calculated from the equations of the temperature

γ-Carboline derivatives were synthesized by the addition of fluorinated vinylpyridines to 2,6-dimethyl-2,3,4,5-tetrahydro-γ-carboline. The effect of repeated intraperitoneal injections of the synthesized derivatives on the progression of motor and cognitive dysfunctions was studied in comparison with Dimebon in 5xFAD transgenic mice as a model of neurodegenerative diseases induced by cerebral amyloidosis

Basic copper(ii) dihydroxoborate Cu2{BO(OH)2}(OH)3 contains infinite chains consisting of [CuO4] squares that are linked together by sharing opposite edges, due to which this compound is interesting in terms of low-dimensional magnetism. However, investigations of its physical properties are hindered by difficulties with the preparation of single-phase samples. The synthesis method was optimized, and

Microspherical particles of composite drugs based on lysozyme and albumin, which can be used in inhalation administration, were prepared by spray drying. The composition of the complexes was determined using experimental and theoretical methods. The use of the protein matrix makes it possible to increase the dissolution rate of the drug in water. The obtained results can be useful for the development

A novel heterogeneous catalytic method for the synthesis of quinoline (1) and a mixture of 2- and 4-methylquinolines (2) by Skraup reaction in the presence of H-Y, H-MOR, H-Beta, H-ZSM-5 zeolite catalysts has been proposed. H-Beta and H-ZSM-5 zeolite catalysts demonstrated the highest activity, selectivity and stability: the total selectivity to 1 and 2 was up to 74% with a dominance of quinoline in

The reaction of P-(morpholin-1-yl)propioamidoxime with aromatic sulfonyl chlorides (p-XC6H4SO2Cl; X = CH3O, CH3, H, Br, Cl, NO2) in chloroform in the presence of triethyl-amine does not produce expected O-arylsulfonyl-β-(morpholin-1-yl)propioamidoximes; instead, this reaction affords isomers of the latter compounds, 2-amino-8-oxa-l,5-diazaspiro[4.5]dec-1-ene-5-ammonium arylsulfonates. The structures

A short and convenient synthesis of exomethylidenecyclopentenone core of cyclopentenone prostaglandins (+)−3 from (−) Corey lactone diol is described. The chiral 5-phenylthio and 5-phenylsulfonyl derivatives of exomethylidenecyclopentenone were obtained and their cytotoxic properties were studied in comparison with the synthesized earlier ethylthio and ethylsulfonyl derivatives of (±)−3, announced

Two approaches to the synthesis of planar chiral (SMn,S)-[2-(quinolin-2-yl)cymantren-1-yl]-p-tolylsulfoxide have been developed. One of them is based on the Negishi cross-coupling reaction, while other one is based on the SNH cross-coupling.

The steric and electronic structures of 1,3-diaza-5-phoaphacyclohexane with the pyridyl substituent at the phosphorus atom and a series of model 1,3-diaza-5-phosphacyclohexanes (potential ligands for the synthesis of luminescent transition metal complexes) were studied using IR and UV spectroscopy combined with quantum chemical calculations. Relationships between the electronic structures, spectral

Hyaluronic acid (HA)-curcumin electrospun fibers exhibiting antimicrobial, anti-inflammatory, and anti-tumorigenic activity were fabricated. It is shown that a metachromatic complex between HA and curcumin is formed in a water-organic medium, thus stabilizing the electro-spinning process and improving the fiber characteristics. The polymer fibers prepared at a voltage of 26 kV have an average diameter

The effect of carbon nanotubes (CNTs) on the morphology and properties of alginate hydrogel was studied. The addition of CNTs leads to a change in the structural characteristics of the hydrogel, which is expressed in a decrease in the pore size and gaining a more uniformity by the internal structure. To study the encapsulating properties of the designed compositions, a set of dyes was used that are

The neurotropic activity of N-(2-acetylaminoethyl)glycoluril derivatives and their analgesic effect were studied. The nootropic activity of glycolurils was investigated for the first time, and a compound with the nootropic effect exceeding that of piracetam was revealed.

New hydroxy derivatives of chalcones obtained via a condensation of 3-acetyl-2H-chromen-2-one with 2,4-dihydroxy- and 4-hydroxy-benzaldehydes and via an aldol crotonic condensation of methyl N-(4-acetylphenyl)carbamate with 4-hydroxy-3,5-di(tert-butyl)benzaldehyde have been isolated and characterized. A wide range of promising biological activity of the synthesized compounds, including the radical

3β,28-Diacetoxylup-20(29)-en-30-oic acid (obtained via oxidation of betulin diacetate) enters the addition reaction with P—H-phosphonium salts (triarylphosphonium trifluoroacetates) under mild conditions to afford β-carboxyalkylphosphonium salts. Structure and composition of the resulting compounds were confirmed by NMR and IR spectroscopy, mass spectrometry, and elemental analysis.

A new method for separation of 97Ru radionuclide from irradiated by a-particles molybdenum, which potentially could be applied in nuclear medicine, is proposed. Carrier-free ruthenium-97 was separated from macroamounts of molybdenum and trace amounts of technetium by extraction chromatography on a commercial DGA sorbent. The distribution of 97Ru in the body organs of mice was studied.

The synthetic scope of ethyl 2-(quinoxalin-2(1H)-on-3-yl)acetates and their mono- and dibromo derivatives in the synthesis of 2,2’-biquinoxaline-3,3’(4H,4’H)-diones was examined.

The review addresses the synthetic potential of cations or hydrols of (aza,thio)xanthenes in reactions with primary and secondary amines and imines. The diversity of reaction pathways that depend on the structures of amines and imines is discussed. Biological activity of (aza,thio)-xanthene derivatives is considered.

The formation of stable complexes of citrus pectin with nonsteroidal anti-inflammatory drugs, ibuprofen and acetylsalicylic acid (aspirin), was confirmed by IR and NMR spectro scopy. The stoichiometry of complexes with the maximum content of drugs (15 wt. %) was established. A comparative study of the thermal decomposition of pectin and the synthesized complexes with ibuprofen and acetylsalicylic acid

A directed synthesis of two progesterone metabolites, allopregnanolone and 3a-hydroxy-pregn-4-en-20-one, from Δ16-pregnanolone and progesterone, respectively, was carried out by a reduction of the carbonyl groups in positions 3 and subsequent inversion of the configuration of the resulting alcohols by the Mitsunobu reaction. The selectivity of the reduction of the conjugated carbonyl group in position

Urotropine is a cheap and promising ligand for the synthesis of metal-organic frameworks containing uncoordinated nitrogen atoms. The reactions between urotropine, dicarboxylic acids, and zinc(II) or cobalt(II) salts were studied. The optimization of the reaction conditions allows the synthesis of three urotropine-containing metal-organic frameworks, [Zn(ur)(abdc)]• •DMF•H2O (1, ur is urotropine, abdc2−

The determination of boron in animal organ tissues using inductively coupled plasma atomic emission spectroscopy (ICP AES) has been optimized for analytical support of boron neutron capture therapy of cancerous tumors. The proposed technique is universal and rapid. The methodology includes: preliminary acid decomposition at elevated temperatures and pressure (if necessary), determination of boron by

Pyridine-3-carbaldehyde reacted with 1-(aryl)ethan-1-ones to give 1,5-diaryl-3-(pyridin-3-yl)pentane-1,5-diones, which were further converted to 2′,6′-bis-aryl-3,4′-bipyridines.

Abstract Pyrrolinium salts containing 3-arylidene fragment were obtained. Their synthesis is based on the reaction of (E)-4-(4-chlorobenzylidene)-3,4-dihydro-2H-pyrrole with various bromo-alkanes. Structures of the obtained compounds were confirmed by a set of physico-chemical analysis methods.

Abstract Available 2-chloro-3-nitropyridines were used to synthesize new representatives of 6-substituted 3-benzoylisoxazolo[4,3-b]pyridines, which were found to react with neutral C-nucleophiles to give 1,4-addition products.