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The effect of gamma radiation on 5-hydroxymethylfurfural conversion in water and dimethyl sulfoxide Open Chem. (IF 2.3) Pub Date : 2024-03-13 Nurulsafeelanaria Benwannamas, Phongphak Sataman, Somprasong Thongkham, Wilasinee Kingkam, Wiranee Sriwiang, Sakchai Laksee, Nicha Prigyai, Tanagorn Sangtawesin, Threeraphat Chutimasakul
5-Hydroxymethylfurfural (HMF) is a biomass-based chemical platform that can undergo many feasible reactions. One of the most important reactions is the oxidation to 2,5-furandicarboxylic acid (FDCA), which is the monomer for bioplastic production. In this work, the radiation method was used to investigate the conversion of HMF in both aqueous (DI) and dimethyl sulfoxide (DMSO) solutions. The effects
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Evaluation of influence of Butea monosperma floral extract on inflammatory biomarkers Open Chem. (IF 2.3) Pub Date : 2024-03-06 Nureen Zahra, Aansa Mazhar, Beenish Zahid, Muhammad Ahsan Naeem, Abid Sarwar, Tariq Aziz, Metab Alharbi, Thamer H. Albekairi, Abdullah F. Alasmari
Butea monosperma is a deciduous tree, widely distributed throughout India, Burma, and Ceylon. The present study was intended to investigate the anti-inflammatory effects of Butea monosperma on the induced inflammatory model by evaluating pro-inflammatory biomarkers and their computational analysis. The anti-inflammatory activity may be attributed to the phyto-constituents for inhibitory effects on
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Cannabis sativa L. essential oil: Chemical composition, anti-oxidant, anti-microbial properties, and acute toxicity: In vitro, in vivo, and in silico study Open Chem. (IF 2.3) Pub Date : 2024-03-06 Rafik El-Mernissi, Naoual El Menyiy, Rania Moubachir, Aziz Zouhri, Yahya El-Mernissi, Farhan Siddique, Sumaira Nadeem, Hind Ibork, Azeddin El Barnossi, Gezahign Fentahun Wondmie, Mohammed Bourhia, Yousef A. Bin Jardan, Oualid Abboussi, Lhoussain Hajji
This study evaluated the volatile components of Cannabis sativa L. essential oils (CSEOs) and their pharmacological potential in vitro, in animal, and in silico. The anti-oxidant capacities of volatile compounds were tested using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), total anti-oxidant capacity (TAC), and gas chromatography-mass spectrometry (GC-MS). Anti-microbial
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Synthesis of multi-template molecularly imprinted polymers (MT-MIPs) for isolating ethyl para-methoxycinnamate and ethyl cinnamate from Kaempferia galanga L., extract with methacrylic acid as functional monomer Open Chem. (IF 2.3) Pub Date : 2024-03-05 Ike Susanti, Anastasya Leatemia Triadenda, Niky Murdaya, Driyanti Rahayu, Rimadani Pratiwi, Yudi Rosandi, Aliya Nur Hasanah
Kaempferia galanga L. extract contains ethyl p-methoxycinnamate (EPMC) and ethyl cinnamate (EC), which have several pharmacological activities. EPMC and EC have been successfully isolated, but the %yield was low. Therefore, developing an isolation method to increase the %yield result of EPMC and EC is essential. The molecularly imprinted polymers have been applied to separate lot of active compounds
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In vivo protective effects of vitamin C against cyto-genotoxicity induced by Dysphania ambrosioides aqueous extract Open Chem. (IF 2.3) Pub Date : 2024-03-05 Laila El-Bouzidi, Ahmed khadra, Manal Zefzoufi, Saida Sissi, Abdelilah El-Abbassi, Khalid Bekkouche, Souad Sellami, Hanane Rais
Dysphania ambrosioides (L.) holds a prominent place in Moroccan folk medicine due to its therapeutic attributes. Despite its widespread use, instances of inadvertent intoxication linked to its consumption have been reported. This study aims to evaluate the potential cytogenotoxic effects of D. ambrosioides leaf aqueous extract (DAAE) and explore the prospective protective role of vitamin C (l-ascorbic
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Phytochemical and physicochemical studies of different apple varieties grown in Morocco Open Chem. (IF 2.3) Pub Date : 2024-03-01 Kara Mohammed, Hamza Saghrouchni, Youness El Abdali, Assouguem Amine, Nouha Haoudi, Mohamed El fadili, Aya Amar, Tareq Hamijo, Isil Var, Riaz Ullah, Zerhouni Abdou Rachid, Bahhou Jamila
The apple is an important part of the human diet and is one of the most popular fruits in Morocco, with varieties that are now suitable for human consumption. This study aims to clarify several aspects of apples, such as their physical and chemical compositions and nutrient profiles. Total polyphenols, flavonoids, tannins, and anthocyanins were determined using spectrophotometer and organic acid compounds
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Two triazole-based coordination polymers: Synthesis and crystal structure characterization Open Chem. (IF 2.3) Pub Date : 2024-02-28 Jing Li, Hongjiang Ren, Jiangtao Li, Liuchang Wang
Here we reported two new triazole-based coordination polymers (CPs), i.e., [Zn(Hdatrz)(μ 2-O)] n (1) together with [Mn(Hdatrz)(C2O4)] n ·n(H2O) (2) (Hdatrz = 3,5-diamino-1,2,4-triazole), which were generated under solvothermal conditions. The influence of different metal ions on the structure and properties of CPs was investigated. The CPs’ whole structures have been completely characterized by the
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Green synthesis, characterization, and application of iron and molybdenum nanoparticles and their composites for enhancing the growth of Solanum lycopersicum Open Chem. (IF 2.3) Pub Date : 2024-02-26 Maria Habib, Hina Fatima, Tauseef Anwar, Huma Qureshi, Samson O. Aisida, Ishaq Ahmad, Iftikhar Ali, Amal M. Al-Mohaimeed, Mohamed S. Elshikh, Sarah Abdul Razak, Asif Kamal
Nanomaterials have become integral in various aspects of agricultural practices, including the development of nano-fertilizers for optimized crop nutrition. This study explores the application of green-synthesized iron (Fe) and molybdenum (Mo) nanoparticles, as well as their composites, using a guava leaf extract (GLE). The focus is on assessing their impact on nitrogen fixation and growth in tomato
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Phytochemical analysis, in vitro antioxidant and antifungal activities of extracts and essential oil derived from Artemisia herba-alba Asso Open Chem. (IF 2.3) Pub Date : 2024-02-23 Faiza EL Hajli, Mohamed Reda Kachmar, Amine Assouguem, Riaz Ullah, Ahmed Bari, Khalil Hammani, Said Chakir, Rachid Lahlali, Essaïd Ait Barka, Ghizlane Echchgadda
Artemisia herba-alba Asso is an endemic plant from North-East Morocco offering a diverse range of pharmacological, cosmetic, and agro-ecological uses. However, Artemisia herba-alba has not been well exploited in the field of plant protection (post-harvest diseases). This is why the main objective of the present study is to evaluate the antifungal and antioxidant activities of extracts or the essential
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Chemical composition and biological properties of Thymus capitatus plants from Algerian high plains: A comparative and analytical study Open Chem. (IF 2.3) Pub Date : 2024-02-22 Noureddine Tamma, Naima Benchikha, Mohammed Messaoudi, Gianluca Caruso, Talha Bin Emran, Ayomide Victor Atoki, Adekunle Ismahil Adeniyi
The Lamiaceae family contains bioactive medicinal compounds mostly used as ornamental plants and traditional medicine, as well as in the food, cosmetics, and pharmaceutical sectors. Common uses include treating high cholesterol, diabetes, respiratory diseases, heart disease, and food poisoning. These medicinal uses were linked to their components and numerous biological properties, including antimicrobial
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Synthesis, characterization, in silico and in vitro studies of novel glycoconjugates as potential antibacterial, antifungal, and antileishmanial agents Open Chem. (IF 2.3) Pub Date : 2024-02-13 Sher Wali Khan, Saira Nayab, Muhammad Naveed Umar, Momin Khan, Anila Iqbal, Nasir Ahmad, Haroon ur Rashid, Muhammad Ishaq Ali Shah, Naila Gulfam, Muhammad Zahoor, Riaz Ullah, Essam A. Ali
In the present work, several new glycoconjugates (8a–e) were generated from glycopyranosyl-α-trichloroacetimidates (sugar-OTCA) as glycosyl donors and dimethyl-l-tartrate as an aglycone acceptor in good to excellent yields. In the synthetic protocol, various monosaccharides were transformed into pentaacetylated derivatives and then into glycopyranosyl-α-trichloroacetimidates. Afterward, the sugar-OTCA
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Sonochemical synthesis of gold nanoparticles mediated by potato starch: Its performance in the treatment of esophageal cancer Open Chem. (IF 2.3) Pub Date : 2024-02-13 Mingwei Liu, Xiaolei Xue, Bikash Karmakar, Waleed Eltantawy, Attalla F. El-kott, Emam M. El. Nashar, Eman M. Abd-Ella
Economically viable and eco-friendly potato starch (PS) was employed to synthesize Au NPs under ultrasound irradiation. PS phytochemicals have the function of a green reductant as well as an efficient stabilizer template to cap and synthesize gold nanoparticles. Transmission electron microscopy (TEM), UV-Vis spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive
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Exploitation of mangliculous marine fungi, Amarenographium solium, for the green synthesis of silver nanoparticles and their activity against multiple drug-resistant bacteria Open Chem. (IF 2.3) Pub Date : 2024-02-12 Mohamed S. Hodhod, Abdel-Rhman Z. Gaafar, Bandar M. AlMunqedhi, Abdalla Elzein, Abdelmalik M. Abdelmalik
The green synthesis pathway for silver nanoparticles (AgNPs) used in bacterial treatment is regarded as crucial because of its cost-effectiveness, nontoxicity, and eco-friendliness. During the present work, the mangliculous marine fungi Amarenographium solium isolated from the Arabian Gulf Coast of Saudi Arabia were utilized for the synthesis of AgNP, through the bio-reduction of aqueous silver nitrate
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Phytochemical study, antioxidant activity, and dermoprotective activity of Chenopodium ambrosioides (L.) Open Chem. (IF 2.3) Pub Date : 2024-02-03 Soufiane Drioua, Otman El-Guourrami, Amine Assouguem, Mouna Ameggouz, Mohammed Kara, Riaz Ullah, Ahmed Bari, Ahmed Zahidi, Azra Skender, Hanane Benzeid, Anass Doukkali
Chenopodium ambrosioides, a member of the Chenopodiaceae family, is renowned for its toxic properties. Despite its toxicity, it has been traditionally utilized in various communities, particularly in pediatric contexts, for its vermifuge, antispasmodic, and antipyretic attributes. This study aims to unravel the phytochemical composition present in organic fractions and aqueous extracts obtained from
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Impact of biogenic zinc oxide nanoparticles on growth, development, and antioxidant system of high protein content crop (Lablab purpureus L.) sweet Open Chem. (IF 2.3) Pub Date : 2024-01-25 Ahmed A. Qahtan, Abdulrahman A. Alatar, Abdalrhaman M. Salih
Lablab (Lablab purpureus L.) Sweet “white” is a vegetable crop belonging to the Fabaceae family, and it has been used in many ways as food, ornamental plant, green manure, and medicinal. In contrast, zinc oxide nanoparticles (ZnO NPs) play an important role in plant growth and development. The aim of this current study was to investigate the impact of biogenic ZnO NPs on the growth, development, and
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Phytochemicals profiling, in vitro and in vivo antidiabetic activity, and in silico studies on Ajuga iva (L.) Schreb.: A comprehensive approach Open Chem. (IF 2.3) Pub Date : 2024-01-23 Mosleh M. Abomughaid, Fatma A. A. El-Shibani, Abdulnaser Kh. Abdulkarim, Amr S. Abouzied, Ghassan M. Sulaiman, Ali M. Abomughayedh, Munira M. F. Abdulsayid, Salim Albukhaty, Naema Elrmali, Ali Z. Al-Saffar, Hend A. El-khawaga, Hamdoon A. Mohammed
Ajuga iva (L.) Schreb. is a well-known antidiabetic medicinal plant used for several traditional medicine aspects in different areas of the world, including Libya. This study includes phytochemical analysis, antidiabetic evaluation, and in silico studies of the plant, A. iva, growing in Libya. The constituents of the plant were profiled using LC-MS/MS-QTOF analysis, and a total of 28 compounds were
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Phytochemical screening and antioxidant activity of Vitex agnus-castus L. Open Chem. (IF 2.3) Pub Date : 2024-01-19 Soufiane Drioua, Hanane Azalmad, Otman El-Guourrami, Mouna Ameggouz, Fatima Zahra Benkhouili, Amine Assouguem, Mohammed Kara, Riaz Ullah, Essam A. Ali, Sezai Ercisli, Hafize Fidan, Hanane Benzeid, Anass Doukkali
This research is dedicated to investigating the antioxidant potential and phytochemical composition of three distinct extracts derived from Vitex agnus-castus L. These extracts, prepared through aqueous (EXA), ethanolic (EXE), and methanolic (EXM) maceration, were chosen based on prior assessments of total polyphenol content in extracts obtained from five solvents with differing polarities: water,
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Biochar from de-oiled Chlorella vulgaris and its adsorption on antibiotics Open Chem. (IF 2.3) Pub Date : 2024-01-18 Wang Feiyan, Zhang Yali, Luo Siling, Chen Zhiqin, Luo Shanshan, Li Wenkui
High-performance biochar was prepared using de-oiled Chlorella vulgaris biomass as the raw material and KOH as the modifying activator. The properties of the biochar as an adsorbent for the removal of tetracycline (TC) and enrofloxacin (ENR) were investigated under different conditions by varying the amount of the Chlorella vulgaris de-oiled biomass (DB) input. The surface structure and physicochemical
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Evaluation of the analgesic and anesthetic properties of silver nanoparticles supported over biodegradable acacia gum-modified magnetic nanoparticles Open Chem. (IF 2.3) Pub Date : 2024-01-18 Binbin Tan, Jun Chen, Wensheng Wang
An ecofriendly and green procedure was adopted to immobilize Ag NPs over acacia gum (GA)-modified magnetic nanoparticles (Fe3O4-GA/Ag NPs) with analgesic and anesthetic properties. In the stepwise modification method, the pre-synthesized Fe3O4 NPs were coated by the gum acacia (GA) that has hydroxyl groups on its backbone and can be used for as a capping, reducing, and stabilizing agent for immobilized
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Treatment of gastric cancer by silver nanoparticles encapsulated by chitosan polymers mediated by Pistacia atlantica extract under ultrasound condition Open Chem. (IF 2.3) Pub Date : 2024-01-11 Song Li, Ya´nan Xu, Fanlu Meng
In this study, we prepared silver nanoparticles (AgNPs) employing ultrasound and chitosan (CS) in the presence of Pistacia atlantica aqueous extract as a non-toxic stabilizing and reducing agent for capping AgNPs with CS in a simple single-step process. The reduction of Ag+ ions into Ag0NPs was indicated by a visual transform in color. UV-Vis studies revealed that the characteristic surface plasmon
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Melanin antibacterial activity of two new strains, SN1 and SN2, of Exophiala phaeomuriformis against five human pathogens Open Chem. (IF 2.3) Pub Date : 2024-01-11 Safaa Benmessaoud, Jaouad Anissi, Mohammed Kara, Amine Assouguem, Younes Gaga, Mouhcine Ajdi, Riaz Ullah, Essam A. Ali, Sezai Ercisli, Hafize Fidan, Sawinder Kaur, Jamila Bahhou
Melanin is an almost ubiquitous pigment of brown to dark black color synthesized by living organisms. It has excellent potential for application in several fields, especially in pharmaceuticals. Yeasts are known for their ability to synthesize pigments, including melanin. These yeasts are considered black yeasts. However, there is little information on the synthesis of melanin by these yeasts. This
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Therapeutic effects of green-formulated gold nanoparticles by Origanum majorana on spinal cord injury in rats Open Chem. (IF 2.3) Pub Date : 2024-01-11 Lifang Jia, Waleed Eltantawy, Mohamed Samir Ahmed Ahmed Zaki, Abulqasim M. Sideeg, Heitham M. Mohammed, Attalla F. El-kott, Diaa Massoud
In a recent study, we evaluated the remedial properties of gold nanoparticles (gold NPs) green-formulated by Origanum majorana on spinal cord injury in rats. UV-Vis, FE-SEM, FT-IR, and TEM tests were applied to characterize the recent gold NPs. The IC50 values of O. majorana, gold NPs, and butylated hydroxytoluene were 382, 250, and 165 µg/mL, respectively, against DPPH. In in vivo tests, 40 male rats
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Wear and corrosion behavior of TiC and WC coatings deposited on high-speed steels by electro-spark deposition Open Chem. (IF 2.3) Pub Date : 2024-01-10 Ersan Mertgenç
Electro-spark deposition (ESD) is one of the most effective methods for improving the surfaces of metallic materials by applying ceramic-based cermet coatings. In this study, TiC and WC coatings were deposited on the surface of AISI M2 high-speed steel using the ESD method. Subsequently, the coated surfaces were examined through microstructure, phase structure, microhardness, friction, wear, and electrochemical
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In vitro protective and anti-inflammatory effects of Capparis spinosa and its flavonoids profile Open Chem. (IF 2.3) Pub Date : 2024-01-10 Ali S. Alqahtani, Fahd A. Nasr, Mohammad Z. Ahmed, Muath Y. Bin Mansour, Abdullah A. Biksmawi, Omar M. Noman, Rashed N. Herqash, Mohammed Al-zharani, Ashraf Ahmed Qurtam, Hassan A. Rudayni
Multiple beneficial effects have been reported to numerous species of Capparis genus. Among these, Capparis spinosa has exhibited several biological benefits, including anti-inflammatory hepatoprotective, antioxidant, and antidiabetic effects. Herein, C. spinosa was extracted with different solvents and the ability of these fractions to suppress nitric oxide (NO) production in RAW 264.7 cells were
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Porous silicon nanostructures: Synthesis, characterization, and their antifungal activity Open Chem. (IF 2.3) Pub Date : 2024-01-09 Marwa Nabil, Mohamed Elnouby, Abdulaziz A. Al-Askar, Przemysław Łukasz Kowalczewski, Ahmed Abdelkhalek, Said I. Behiry
The use of synthetic pesticides has come under scrutiny, and there has been a subsequent shift toward the investigation of alternative methods for the treatment of plant diseases. One notable advancement in this field is the utilization of porous silicon (PS) powder as a sustainable antifungal agent. The synthesis of PS nanoparticle (PS-NP) powder was carried out using the environmentally friendly
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Green synthesis of AgNPs using plant extract and investigation of its anti-human colorectal cancer application Open Chem. (IF 2.3) Pub Date : 2024-01-09 Yuze Zhai, Benjun Wang, Weiwei Han, Bianfang Yu, Jichen Ci, Fan An
Recently, the plant extracts used to synthesize nanoparticles (NPs) have been considered an excellent alternative to physical and chemical ways. The applications of NPs in the fields of agriculture, industry, and medicine are so many and diverse that they cannot be counted. In recent years, silver nanoparticles (AgNPs) have attracted the consideration of several scientists because of their special
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The adsorption of naproxen on adsorbents obtained from pepper stalk extract by green synthesis Open Chem. (IF 2.3) Pub Date : 2024-01-09 Hacer Dolas
This study presented the adsorption of naproxen on adsorbents filled with Cu, Fe, and Cu/Fe nanoparticles (NPs) obtained by the green synthesis method from pepper stem waste. The resulting adsorbents were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy-energy dispersive X-ray spectroscopy, and thermal gravimetric-differential thermal analysis. The amount of naproxen
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Phytochemical analysis and antifungal efficiency of Origanum majorana extracts against some phytopathogenic fungi causing tomato damping-off diseases Open Chem. (IF 2.3) Pub Date : 2024-01-06 Fatimah Al-Otibi, Reem A. Alshahrani, Raedah I. Alharbi, Mohamed Taha Yassin
Plant diseases represent one of the major problems causing yield loss of tomato crops, especially root rot and seedling damping-off diseases caused by some phytopathogenic fungi like Fusarium solani (Fs), F. oxysporum (Fo), and Macrophomina phaseolina (Mp) frequently detected in tomato either alone or in combination infection. The objective of the present study is to assess the antifungal activity
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Nanostructured p-PbS/p-CuO sulfide/oxide bilayer heterojunction as a promising photoelectrode for hydrogen gas generation Open Chem. (IF 2.3) Pub Date : 2024-01-06 Mohamed Zayed, Mamduh J. Aljaafreh, Mohamed Shaban, Mahmoud Hezam, Sodky H. Mohamed, Mohamed Rabia, Mohammad Marashdeh, M. Al-Hmoud, Ashour M. Ahmed
Recently, the photoelectrochemical (PEC) water-splitting reaction for hydrogen (H2) production has been a competitive research route to realize clean and sustainable electric power. In this work, copper oxide (CuO) and PbS thin films were fabricated on commercial glass, respectively, using the techniques of successive ionic-layer adsorption and reaction and chemical bath deposition. These nanostructured
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Characteristics of Langmuir monomolecular monolayers formed by the novel oil blends Open Chem. (IF 2.3) Pub Date : 2024-01-03 Wiktoria Kamińska, Wojciech Cichocki, Hanna Maria Baranowska, Katarzyna Walkowiak, Dominik Kmiecik, Przemysław Łukasz Kowalczewski
The aim of this work was to assess the physical properties of Langmuir monolayers of three new oil blends “RBWg” (obtained by mixing rapeseed oil, black cumin oil, and wheat germ oil), “REp” (rapeseed oil and evening primrose oil), and “CRb” (camelina oil and rice bran oil), as well as to characterize the molecular dynamics of their protons using low-field nuclear magnetic resonance (LF NMR) method
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Unraveling the therapeutic potential of Bombax ceiba roots: A comprehensive study of chemical composition, heavy metal content, antibacterial activity, and in silico analysis Open Chem. (IF 2.3) Pub Date : 2023-12-25 Ali Alrabie, Mohammed ALSaeedy, Arwa Al-Adhreai, Inas Al-Qadsy, Abdel-Basit Al-Odayni, Waseem Sharaf Saeed, Ahmed Hasan, Mazahar Farooqui
This study sought to assess the heavy metal content, phytochemical composition, antibacterial activity, and absorption, distribution, metabolism, and excretion (ADME) properties of Bombax ceiba L. tree. The heavy metal content of the plant roots was determined using inductively coupled plasma-mass spectrometry technique, and it was found that only Cr, Mn, Fe, and Ni concentrations were above the permissible
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Oleic acid and linoleic acid nanosomes boost immunity and provoke cell death via the upregulation of beta-defensin-4 at genetic and epigenetic levels Open Chem. (IF 2.3) Pub Date : 2023-12-23 Gamaleldin I. Harisa, Ibrahim Najashi, Ahmed H. Bakheit, Sabry M. Attia, Fars K. Alanazi, Salim S. Al-Rejaie, Mohamed Mohany
Host defense peptides (HDPs) are encouraged as anticancer and antimicrobial agents. Thus, this study aimed to investigate the effect of oleic acid (OA)- and linoleic acid (LA)-loaded nanosomes on the gene expression of beta-defensin-4 (BD-4) as a member of HDPs. The OA and LA nanosomes were prepared and characterized in terms of particle size and surface charge as lymphatic delivery systems. Afterwards
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Strategies for optimizing the single GdSrFeO4 phase synthesis Open Chem. (IF 2.3) Pub Date : 2023-12-22 Kairat Maratuly Kenges, Ekaterina Alekseevna Tugova
This work provides data on strategies for single GdSrFeO4 phase solid state synthesis. Earlier works have shown that under the solid-state synthesis conditions, the GdSrFeO4 preparation is hampered by the formation of non-target product: Gd2SrFe2O7. This work approach led to the solid-phase synthesis GdSrFeO4 scheme change. GdSrFeO4 was characterized by X-Ray, scanning electron microscopy/energy dispersive
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Characteristics, source, and health risk assessment of aerosol polyaromatic hydrocarbons in the rural and urban regions of western Saudi Arabia Open Chem. (IF 2.3) Pub Date : 2023-12-21 Mohamed I. Orif, Mohammad S. El-Shahawi, Iqbal M. I. Ismail, Hassan Alshemmari, Ahmed Rushdi, Mohammed A. El-Sayed
Air quality represents one of the most important parameters determining indoor microclimate and human comfort. Thus, the current study reports a comprehensive study on the dominant sources, organic compositions, and potential health impacts of the polyaromatic hydrocarbons (PAHs) in the atmospheric particle matters (PMs) ranging from 2.5 µm (PM2.5) to 10 µm (PM10) size in the rural and urban regions
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Evaluation and chemical characterization of bioactive secondary metabolites from endophytic fungi associated with the ethnomedicinal plant Bergenia ciliata Open Chem. (IF 2.3) Pub Date : 2023-12-20 Jiwan Raj Prasai, Senthuran Sureshkumar, Waseem Ahmad, Mohammad Ashraf, Chinnadurai Gopi, Pandy Rajapriya, Abeer S. Aloufi, Nandakumar Natarajan, Mohan Pandi
The objective of this work was to assess the bioactive potential of endophytic fungi, Colletotrichum brevisporum (JPSK3), Pestalotiopsis microspora (JPSK19), and Guignardia mangiferae (JPSK25), from Bergenia ciliata. The antibacterial effects were determined by the well diffusion technique against human pathogens (Staphylococcus aureus, Escherichia coli, Bacillus cereus, and Salmonella typhi) and they
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Advances in the pharmaceutical research of curcumin for oral administration Open Chem. (IF 2.3) Pub Date : 2023-12-20 Cheng Li, Abid Naeem, Jiangwen Shen, Weiwei Zha, Qingyun Zeng, Peng Zhang, Lin Li, Zhenggen Liao, Xulong Chen
Curcumin is an isolated phytopolyphenol pigment found in the Curcuma longa, commonly known as turmeric, with various pharmacological properties. It has many effects, including anti-tumour, anti-inflammatory, anti-bacterial, anti-oxidation, and hypoglycemic properties. However, due to its oral bioavailability, the use of the drug in the clinical environment is limited. Moreover, curcumin’s low bioavailability
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Characteristics, source, and health risk assessment of aerosol polyaromatic hydrocarbons in the rural and urban regions of western Saudi Arabia Open Chem. (IF 2.3) Pub Date : 2023-12-20 Mohamed I. Orif, Mohammad S. El-Shahawi, Iqbal M. I. Ismail, Hassan Alshemmari, Ahmed Rushdi, Mohammed A. El-Sayed
Air quality represents one of the most important parameters determining indoor microclimate and human comfort. Thus, the current study reports a comprehensive study on the dominant sources, organic compositions, and potential health impacts of the polyaromatic hydrocarbons (PAHs) in the atmospheric particle matters (PMs) ranging from 2.5 µm (PM2.5) to 10 µm (PM10) size in the rural and urban regions
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Characterization and antioxidant potential of white mustard (Brassica hirta) leaf extract and stabilization of sunflower oil Open Chem. (IF 2.3) Pub Date : 2023-12-19 Muhammad Riaz, Maria Nawaz, Rahman Qadir, Shabbir Hussain, Taleeha Roheen, Muhammad Afzal, Muhammad Perviaz, Akbar Ali, Tariq Aziz, Metab Alharbi, Thamer H. Albekairi, Abdullah F. Alasmari
The current study aimed to analyze the stabilization of sunflower oil using white mustard (Brassica hirta) leaf extracts as well as their antioxidant potential and cytotoxicity. Selected plant leaves were macerated in different solvents such as n-hexane, chloroform, ethyl acetate, n-butanol, and methanol. The total flavonoid contents, total phenolic contents, the antioxidant activity by DPPH assay
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Treatment of denture stomatitis using iron nanoparticles green-synthesized by Silybum marianum extract Open Chem. (IF 2.3) Pub Date : 2023-12-13 Xiaoming Lin, Cuiping Bu, Jiangling Su
Stomatitis or generalized inflammation of the mouth includes inflammation or pain in the mouth. Natural compounds are one of the best options for stomatitis treatment. Silybum marianum has many medicinal properties in traditional medicine. In recent research, iron nanoparticles were formulated by S. marianum. The research aim was to determine the Fe nanoparticles’ (FeNPs) efficacy in denture stomatitis
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Enhancing photovoltaic efficiency with SQI-Br and SQI-I sensitizers: A comparative analysis Open Chem. (IF 2.3) Pub Date : 2023-12-11 Sultan A. Al-horaibi, Abdel-Basit Al-Odayni, Mohammed ALSaeedy, Fares Hezam Al-Ostoot, Adel Al-Salihy, Jawaher Q. Ghaleb, Arwa Al-Adhreai, Faizaa A. Saif, Salama A. Yaseen, Waseem Sharf Saeed
This study investigates the use of halogen bonding to enhance the effectiveness of short-circuit current density (J SC) in dye-sensitized solar cells (DSSCs). To improve the performance of DSSCs, two dyes, SQI-Br and SQI-I, based on halogen atom-functionalized unsymmetrical squaraine dyes, were designed. These dyes were tested in DSSCs using iodolyte electrolytes (Z-50 and Z-100), and their performance
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Clay-based bricks’ rich illite mineral for gamma-ray shielding applications: An experimental evaluation of the effect of pressure rates on gamma-ray attenuation parameters Open Chem. (IF 2.3) Pub Date : 2023-11-30 K. A. Mahmoud, M. W. Marashdeh
The objective of this study is to increase the natural clay mineral-based bricks’ ability to shield γ-rays without the use of external doping materials. Six brick samples were consequently developed at various pressure rates (PRs). The chemical composition and structure of the manufactured bricks are unaffected by the PR applied. The main constituents in the clay used to make bricks are illite and
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Some anticancer agents as effective glutathione S-transferase (GST) inhibitors Open Chem. (IF 2.3) Pub Date : 2023-11-30 Başak Gökçe
The objective of this research was to investigate the impact of anthraquinone (AQ) compounds on the activity of the enzyme glutathione S-transferase (GST). The interaction between GST and some AQs (alizarin, purpurin, quinizarin, and dantron) was investigated, and IC50 and K i levels were determined for each compound. The results obtained reveal that these compounds are potent GST inhibitors. K i values
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Stability kinetics of orevactaene pigments produced by Epicoccum nigrum in solid-state fermentation Open Chem. (IF 2.3) Pub Date : 2023-11-30 Sawinder Kaur, Paramjit S. Panesar, Sushma Gurumayum, Jyoti Singh, Amine Assouguem, Abderrahim Lazraq, Riaz Ullah, Essam A. Ali, Azra Skender, Prasad Rasane
Orevactaene yellow pigment was produced by solid-state fermentation of broken rice using Epicoccum nigrum. The pigment was extracted using water as a solvent and subjected to stability studies at different temperatures (30, 40, 60, and 80°C), pH (4, 6, and 8), sterilization, and sunlight exposure treatment. The observed data were fitted in the first-order kinetic model. Yellow pigment stability was
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Antibacterial and biofilm prevention metabolites from Acanthophora spicifera Open Chem. (IF 2.3) Pub Date : 2023-11-28 Fitri Budiyanto, Nawal A. Albalawi, Mohamed A. Ghandourah, Tariq R. Sobahi, Magda M. Aly, Hanan F. Althagbi, Samah S. Abuzahrah, Walied M. Alarif
Acanthophora spicifera harbors a diverse array of secondary metabolites with therapeutic potential. The aim of this study is to isolate and characterize secondary metabolites from A. spicifera and then evaluate the antiproliferation, antibacterial, and biofilm prevention properties, followed by an analysis of molecular docking experiments. By employing chromatographic analysis and NMR spectroscopy
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Utilization of computational methods for the identification of new natural inhibitors of human neutrophil elastase in inflammation therapy Open Chem. (IF 2.3) Pub Date : 2023-11-24 Abdulrahim A. Alzain, Fatima A. Elbadwi, Ahmed A. Al-Karmalawy, Rashid Elhag, Wadah Osman, Ramzi A. Mothana
Human neutrophil elastase (HNE) plays a crucial role in causing tissue damage in various chronic and inflammatory disorders, making it a target for treating inflammatory diseases. While some inhibitors of HNE’s activity have been identified, only a few have made it to clinical trials. In this study, computational methods were employed to identify potential natural products (NPs) capable of targeting
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Preparation of newly developed porcelain ceramics containing WO3 nanoparticles for radiation shielding applications Open Chem. (IF 2.3) Pub Date : 2023-11-22 Dalal A. Aloraini, Mohammad Ibrahim Abualsayed, Aljawhara H. Almuqrin, Mohamed Elsafi
We fabricated porcelain ceramics embedded with WO3 nanoparticles (NPs) for radiation shielding applications. The linear attenuation coefficients were experimentally determined to study the efficiency of the manufactured samples against gamma rays. When the thickness increases from 0.5 to 2 cm, there is a reduction in the photon transmission through the ceramics. At 0.662 MeV, the transmission factor
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Treatment of gastric cancer by green mediated silver nanoparticles using Pistacia atlantica bark aqueous extract Open Chem. (IF 2.3) Pub Date : 2023-11-22 Ling Dang, Jian Yang, Sally Negm, Attalla F. El-kott, Ali A. Shati, Heba I. Ghamry, Bikash Karmakar
We herein demonstrate a novel green mediated silver nanoparticles (AgNPs) using Pistacia atlantica bark aqueous extract for the treatment of gastric cancer under in vitro conditions. Physicochemical and structural features of the nanocomposite biomaterial were assessed by several techniques like UV-Vis spectrum, transmission electron spectroscopy, field emission scanning electron microscopy, energy-dispersive
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Effects of green decorated AgNPs on lignin-modified magnetic nanoparticles mediated by Cydonia on cecal ligation and puncture-induced sepsis Open Chem. (IF 2.3) Pub Date : 2023-11-22 Lei Zhou, Yanfen Yao, Quanzhen Wang, Peng Wang, Shan Hong, Li Kong
Sepsis is a common and deadly syndrome that despite all the progress in its control, the death rate caused by it is high. Sepsis is a serious problem that needs immediate attention and treatment. This infection, especially if it is caused by bacteria resistant to several drugs, causes high mortality. About two-thirds of sepsis cases occur in hospitalized patients. Several factors such as increasing
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Protective properties of AgNPs green-synthesized by Abelmoschus esculentus on retinal damage on the virtue of its anti-inflammatory and antioxidant effects in diabetic rat Open Chem. (IF 2.3) Pub Date : 2023-11-21 Fang Tang, Behnam Mahdavi
Eye retinopathy means damage to the retina of the eye, which can have various causes, both congenital and acquired. Diabetes is one of the important causes of eye retinopathy. Retinopathy can develop slowly or quickly, get better on its own, or lead to permanent damage. No treatment is recommended in the early and mild stages. However, close monitoring is essential. Severe form of the disease may require
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Lewis acids as co-catalysts in Pd-based catalyzed systems of the octene-1 hydroethoxycarbonylation reaction Open Chem. (IF 2.3) Pub Date : 2023-11-17 Kairzhan Shalmagambetov, Andrea Vavasori, Gulbanu Zhaksylykova, Fatima Kanapiyeva, Meruyert Zykay, Nurbolat Kudaibergenov
In this work, in order to develop new, efficient, and environmentally friendly methods for the preparation of practically valuable esters of carboxylic acids, the hydroalkoxycarbonylation reaction of octene-1 with various alcohols in the presence of metal–complex catalysts based on palladium phosphine complexes has been studied. Three-component systems based on PdCl2(PPh3)2 containing different ligands
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Physicochemical characterization, antioxidant and antifungal activities of essential oils of Urginea maritima and Allium sativum Open Chem. (IF 2.3) Pub Date : 2023-11-17 Khaoula Mzioud, Amar Habsaoui, Hamada Imatra, Sara Haida, Sara Rached, Soukaina Msairi, Allal Douira, Ali S. Alqahtani, Omar M. Noman, Mahmoud Tarayrah, Mohamed Ebn Touhami
This study aims to contribute to the valorizing of aromatic and medicinal plants of Morocco by studying the antioxidant and antifungal properties of the essential oils (EOs) of Allium sativum (AS) (garlic) and Urginea maritima (Syn. Drimia maritima) tested in vitro. After the hydrodistillation of EOs, we determined their physicochemical indices according to an international standard (Moroccan ISO standard)
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Perinatal supplementation with selenium nanoparticles modified with ascorbic acid improves hepatotoxicity in rat gestational diabetes Open Chem. (IF 2.3) Pub Date : 2023-11-10 Ahmed M. Rady, Hossam Ebaid, Mohamed Habila, Iftekhar Hassan, Jameel Al-Tamimi, Ibrahim M. Alhazza, Mohamed S. Moshab, Zeid A. ALOthman
Because of the potential bioactivities, nanoparticles have engendered hope in scientific communities for developing novel therapeutic strategies. In the present study, it was tested whether selenium nanoparticles (Se-NPs) can protect the liver in mothers with gestational diabetes (DM). The gestational rats were divided into three groups (n = 8). Group 1 (CN) received the vehicle, Group 2 (DM) received
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Comprehensive study of optical, thermal, and gamma-ray shielding properties of Bi2O3–ZnO–PbO–B2O3 glasses Open Chem. (IF 2.3) Pub Date : 2023-11-09 Mohammad Ibrahim Abualsayed, Dalal Abdullah Aloraini, Aljawhara H. Almuqrin, Ashok Kumar
The Bi2O3–ZnO–PbO–B2O3 (BiZPB) glasses are prepared using the melt-quenching technique. As the concentration of lead oxide increases, the band gap energy (E g) decreases from 2.864 to 2.671 eV. The BiZPB glasses exhibit remarkable stability under thermal stress, as indicated by the thermogravimetric analysis graph, with only a marginal 0.5% loss in their initial mass. The decrease in the glass transition
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Alteration in the molecular structure of the adenine base exposed to gamma irradiation: An ESR study Open Chem. (IF 2.3) Pub Date : 2023-11-09 Keziban Usta
Adenine polycrystals were obtained from their powder form under effective crystallization conditions by adjustment of the concentration of chemical solutions. The adenine samples were irradiated with a 60Co gamma-ray source at room temperature for 12, 24, 48, and 72 h, and then these samples were investigated between 240 and 400 K using an electron spin resonance (ESR) spectrometer. No signals were
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In vitro exploration of Hypsizygus ulmarius (Bull.) mushroom fruiting bodies: Potential antidiabetic and anti-inflammatory agent Open Chem. (IF 2.3) Pub Date : 2023-11-09 Lena Ahmed Saleh Al-Faqeeh, Rafiuddin Naser, Kagne SR, Subur W. Khan, Inas Al-Qadsy, Ahmed S. Haidyrah, Ahmad Abdulaziz Al-Owais, Maria Christy, Waseem Sharaf Saeed
The growing interest in exploring mushrooms and their bioactive components as potential therapies for diabetes and inflammatory conditions has prompted our investigation. In this study, we examined the methanolic extract, as well as the petroleum ether and ethyl acetate fractions, derived from the fruiting bodies of Hypsizygus ulmarius and assessed the potential in vitro anti-inflammatory and anti-diabetic
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Investigation of structural, dielectric, impedance, and mechanical properties of hydroxyapatite-modified barium titanate composites for biomedical applications Open Chem. (IF 2.3) Pub Date : 2023-11-06 Khalid Elfaki Ibrahim, Hamoud A. Kassim
This report presents the synthesis of pristine barium calcium titanate (BCT) and composite samples of [x(HA)–100 − x(BCT)]; (0 ≤ x ≤ 20) through solid-state reaction with microwave sintering. Hydroxyapatite (HA)–BCT composites have been developed to minimize grain growth, thereby boosting the material’s physical, mechanical, and electrical properties. The evaluated samples were examined for the Fourier
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Metal gel particles loaded with epidermal cell growth factor promote skin wound repair mechanism by regulating miRNA Open Chem. (IF 2.3) Pub Date : 2023-11-06 Yanfeng Bian, Shizhou Liu, Jing Huang, Tianlong Ma
Skin wounds are prone to fungal infections and may threaten patients’ lives in severe cases. However, conventional treatment protocols rarely promote skin wound repair by modulating microRNA (miRNA). A novel binuclear cobalt(ii) complex with the chemical formula [Co2(MBBA)2(HPT)2(H2O)2]·2H2O (1) was synthesized through the reaction of 2-(4-methylbenzoyl) benzoic acid and 3-(pyridin-2-yl)-1H-1,2,4-triazole
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Color tunable benzothiadiazole-based small molecules for lightening applications Open Chem. (IF 2.3) Pub Date : 2023-11-03 Nusret Kaya
2,1,3-Benzothiadiazole (BTD) is a key motif for the chemistry of photoluminescence molecules and its application in lightening technology as well as cell imagining. Evaluating the characteristics and reaction mechanisms of the BTD derivatives in molecular is critical for molecular designing. Research has been turned to BTD-extended derivatives owing to their possible usage in organic photovoltaics
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Bordeaux mixture accelerates ripening, delays senescence, and promotes metabolite accumulation in jujube fruit Open Chem. (IF 2.3) Pub Date : 2023-11-02 Qianjin Wang, Shan Tian, Xuehui Duan, Mengqian Zhang, Xusheng Zhao, Yueyue Li
The old, but eco-friendly pesticide, Bordeaux mixture (Bm), is widely used in agriculture. Here, the effects of Bm on preharvest fruit ripening, and postharvest senescence of fruit and the accumulation of antioxidants were studied in Ziziphus jujuba. A 200× dilution of Bm enhanced preharvest ripening and retarded jujube fruit postharvest senescence. Treatment with Bm increased the reddening index and
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Important application value of injectable hydrogels loaded with omeprazole Schiff base complex in the treatment of pancreatitis Open Chem. (IF 2.3) Pub Date : 2023-11-02 Jingrong Ma, Chaoqun Du, Yuehua Zhang, Jing Zhan, Yafang Lai, Mingwei Zhao
In this study, a novel Ho(iii) coordination complex with the chemical composition of [Ho6(acac)4L4(CH3O)6]·xCH3OH (1) has been prepared via using a polydentate Schiff base ligand N′-(2,3-dihydroxybenzylidene) picolinohydrazide (H2L) and a β-diketone (Hacac = acetylacetone) co-ligand, and then successfully loaded with drug omeprazole. Hyaluronic acid, a natural polysaccharide with good biocompatibility