-
Effectiveness of removal of sulphur compounds from the air after 3 years of biofiltration with a mixture of compost soil, peat, coconut fibre and oak bark Open Chem. (IF 1.216) Pub Date : 2020-12-31 Anna Chmielowiec-Korzeniowska; Leszek Tymczyna; Bożena Nowakowicz-Dębek; Magdalena Dobrowolska
The aim of the study was to assess the impact of the duration of the use of a biofiltration bed on the efficiency of biofiltration of sulphur compounds and on the physicochemical and microbiological properties of the bed. The study was carried out at an animal waste treatment plant. Two biofiltration chambers (beds A and B) filled with different organic mixtures (compost soil, peat, coconut fibre and
-
A new phenyl alkyl ester and a new combretin triterpene derivative from Combretum fragrans F. Hoffm (Combretaceae) and antiproliferative activity Open Chem. (IF 1.216) Pub Date : 2020-12-31 Isaac Silvère Gade; Corinne Chadeneau; Richard Tagne Simo; Emmanuel Talla; Alex De Theodore Atchade; Paule Seité; Brigitte Vannier; Sophie Laurent; Celine Henoumont; Armel H. Nwabo Kamdje; Jean-Marc Muller
This work concerns the isolation and structure elucidation of compounds obtained from the extract of leaves and stem bark of Combretum fragrans F. Hoffm. Both extracts and some isolated compounds were tested for antiproliferative activity on glioblastoma (U87MG and C6 cells) and prostate (PC-3 cells) cancer cell lines using XTT (2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxyanilide
-
A study of in vitro metabolism and cytotoxicity of mephedrone and methoxetamine in human and pig liver models using GC/MS and LC/MS analyses Open Chem. (IF 1.216) Pub Date : 2020-12-23 Majed Alshamaileh; Issam Hussain; Mark Baron; Ruth Croxton; Marleen Vetter; Jose Gonzalez-Rodriguez
In the current study, the metabolism of two novel psychoactive substances (NPSs), mephedrone and methoxetamine (MXE), was studied in vitro in pig liver microsomes to determine potential metabolites by liquid chromatography-mass spectrometry (LC-MS). Later, in vitro studies were performed using HepaRG™ cells to determine the human metabolites of these drugs using gas chromatography-mass spectrometry
-
Screening and analysis of xanthine oxidase inhibitors in jute leaves and their protective effects against hydrogen peroxide-induced oxidative stress in cells Open Chem. (IF 1.216) Pub Date : 2020-12-16 Lang Zhang; Liangliang Liu; Aiping Xiao; Siqi Huang; Defang Li
Jute (Corchorus capsularis L.) is an annual herb of the bast fiber plant and has great potentials in food and medicinal usages because of its various bioactivities. In this study, ultrafiltration coupled with high-performance liquid chromatography-mass spectrometry was established for screening xanthine oxidase inhibitors from the jute leaves extract. Under the optimum screening conditions, three inhibitors
-
Influence of site-classification approach on geochemical background values Open Chem. (IF 1.216) Pub Date : 2020-12-11 Rimantė Zinkutė; Ričardas Taraškevičius; Margarita Jankauskaitė; Vaidotas Kazakauskas; Žilvinas Stankevičius
This study of peri-urban minerogenic topsoil on glacigenic or post-glacial deposits shows the influence of the site-classification approach on the differentiated median background (DMB) values of major elements and the potentially harmful elements (PHEs) Ba, Cr, Cu, Mn, Ni, Pb and Zn. Composite samples from forests and meadows were taken in 25 sites, each of which had five sub-sites. A fraction of
-
Application of selenium and silicon to alleviate short-term drought stress in French marigold (Tagetes patula L.) as a model plant species Open Chem. (IF 1.216) Pub Date : 2020-12-12 Tomasz Kleiber; Klaudia Borowiak; Tomasz Kosiada; Włodzimierz Breś; Bartosz Ławniczak
Selenium (Se) and silicon (Si) are the beneficial elements that may significantly modify plants’ tolerance to various types of biotic and abiotic stress. They may be particularly important due to the current climate changes. The aim of model experiments was to assess how selenium and silicon could alleviate short-term drought stress in French marigold (Tagetes patula L. “Pascal”). Tagetes plant species
-
Synthesis and physicochemical studies of a series of mixed-ligand transition metal complexes and their molecular docking investigations against Coronavirus main protease Open Chem. (IF 1.216) Pub Date : 2020-12-14 Ranjan K. Mohapatra; V. P. Saikishore; Mohammad Azam; Susanta K. Biswal
A novel series of mixed-ligand complexes of the type, [M(L1)(L2)Cl]·2H2O [L1 = 2-(α-methyl salicylidene hydrazine) benzimidazole (primary ligand), L2 = 2,2′-bipyridine (bipy; secondary ligand), M = Co(ii), Ni(ii), Cu(ii) and Zn(ii)], were based on the physicoanalytical studies. The spectroscopic findings revealed tridentate nature of the Schiff base ligand (L1) and its coordination to the metal ions
-
Evaluation of elastomeric heat shielding materials as insulators for solid propellant rocket motors: A short review Open Chem. (IF 1.216) Pub Date : 2020-12-05 Javier Carlos Quagliano Amado; Pablo Germán Ross; Natália Beck Sanches; Juliano Ribeiro Aguiar Pinto; Jorge Carlos Narciso Dutra
This review addresses a comparison, based on the literature, among nitrile rubber (NBR), ethylene-propylene-diene-monomer rubber (EPDM), and polyurethane (PU) elastomeric heat shielding materials (EHSM). Currently, these are utilized for the insulation of rocket engines to prevent catastrophic breakdown if combustion gases from propellant reaches the motor case. The objective of this review is to evaluate
-
Antimicrobial and antifungal activities of bifunctional copper(ii) complexes with non-steroidal anti-inflammatory drugs, flufenamic, mefenamic and tolfenamic acids and 1,10-phenanthroline Open Chem. (IF 1.216) Pub Date : 2020-12-06 Lenka Hudecova; Klaudia Jomova; Peter Lauro; Miriama Simunkova; Saleh H. Alwasel; Ibrahim M. Alhazza; Jan Moncol; Marian Valko
Copper(ii) complexes represent a promising group of compounds with antimicrobial and antifungal properties. In the present work, a series of Cu(ii) complexes containing the non-steroidal anti-inflammatory drugs, tolfenamic acid, mefenamic acid and flufenamic acid as their redox-cycling functionalities, and 1,10-phenanthroline as an intercalating component, has been studied. The antibacterial activities
-
Effects of ageing on the surface characteristics and Cu(ii) adsorption behaviour of rice husk biochar in soil Open Chem. (IF 1.216) Pub Date : 2020-12-02 Zhaoqin Huang; Linchao Hu; Jingyu Dai
The properties of rice husk biochar during the ageing process in soil and the resulting impacts on sorption capacity with respect to Cu(ii) were assessed. Rice husk-derived biochar was placed in fabric bags and buried in a plastic incubator filled with soil for 0–240 d. The aged biochar was then characterised and its sorption capacity compared with control (unaged) biochar in batch sorption experiments
-
Adsorption and sugarcane-bagasse-derived activated carbon-based mitigation of 1-[2-(2-chloroethoxy)phenyl]sulfonyl-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl) urea-contaminated soils Open Chem. (IF 1.216) Pub Date : 2020-12-01 Khuram Shahzad Ahmad; Iqra Amjad; Daoud Ali
Burgeoning pesticide usage in agriculture sector required to be evaluated by assessing the adsorption rate in soils. The herbicide triasulfuron was used in this research to analyze its sorption behavior in seven distinct soils using batch equilibrium methodology. The adsorption coefficient (K d) values ranged from the 3.32 to 29.7 µg/mL. Peshawar soil displayed the highest K d value because of the
-
Corrosion study of copper in aqueous sulfuric acid solution in the presence of (2E,5E)-2,5-dibenzylidenecyclopentanone and (2E,5E)-bis[(4-dimethylamino)benzylidene]cyclopentanone: Experimental and theoretical study Open Chem. (IF 1.216) Pub Date : 2020-11-27 Veprim Thaçi; Ramiz Hoti; Avni Berisha; Jane Bogdanov
The corrosion behavior of copper in 0.1 M aqueous sulfuric acid medium has been studied using potentiodynamic polarization measurements, quantum chemical calculations, and molecular dynamic simulations in the presence and absence of (2E,5E)-2,5-dibenzylidenecyclopentanone (M1) and (2E,5E)-bis[(4-dimethylamino)benzylidene]cyclopentanone (M2). The compounds were freshly prepared in high yields via the
-
Investigations of metallic elements and phenolics in Chinese medicinal plants Open Chem. (IF 1.216) Pub Date : 2020-11-27 Pawel Konieczynski; Aleksej Zarkov; Agnieszka Viapiana; Mateusz Kaszuba; Lukasz Bielski; Marek Wesolowski
Traditional Chinese Medicines (TCM) can be contaminated with heavy metals, and therefore, the aim of this study is to analyze the Fe, Mn, Zn, Cu, Cd, Pb, Cr, and phenolic compounds contents in TCM plants used against civilization diseases. Metals were determined by flame atomic absorption spectroscopy (FAAS) for Fe, Mn, Zn, and Cu and inductively coupled plasma-optical emission spectroscopy (ICP-OES)
-
M-polynomial and topological indices of zigzag edge coronoid fused by starphene Open Chem. (IF 1.216) Pub Date : 2020-11-23 Farkhanda Afzal; Sabir Hussain; Deeba Afzal; Saira Hameed
Chemical graph theory is a subfield of graph theory that studies the topological indices for chemical graphs that have a good correlation with chemical properties of a chemical molecule. In this study, we have computed M-polynomial of zigzag edge coronoid fused by starphene. We also investigate various topological indices related to this graph by using their M-polynomial.
-
A turbidity sensor development based on NL-PI observers: Experimental application to the control of a Sinaloa’s River Spirulina maxima cultivation Open Chem. (IF 1.216) Pub Date : 2020-11-23 Gerardo Flores; Abraham Efraim Rodriguez-Mata; Leonel Ernesto Amabilis-Sosa; Victor Alejandro Gonzalez-Huitron; Omar Hernández-González; Pablo Antonio Lopéz-Peréz
This article addresses the problem of controlling the growth of microalgae originating in Mexican rivers, especially in the state of Sinaloa, Culiacan River. For this purpose, a robust, high-gain nonlinear observer is proposed to estimate the unknown disturbance in the cultivation of mixotrophic microalgae with the presence of organic nutrients. Once a perturbation function related to the change of
-
Deep desulfurization of sintering flue gas in iron and steel works based on low-temperature oxidation Open Chem. (IF 1.216) Pub Date : 2020-11-24 Hua Meng
The deep desulfurization method of sintering flue gas based on the low-temperature oxidation method is studied. Based on the analysis of the main principle of deep desulfurization of sintering flue gas, a deep desulfurization system of sintering flue gas is constructed, which is composed of an absorption washing unit and a washing solution treatment unit. Sodium hydroxide solution is used as the desulfurizing
-
Development of a solventless stir bar sorptive extraction/thermal desorption large volume injection capillary gas chromatographic-mass spectrometric method for ultra-trace determination of pyrethroids pesticides in river and tap water samples Open Chem. (IF 1.216) Pub Date : 2020-11-04 Mona Sargazi; Mark Bücking; Massoud Kaykhaii
Stir bar sorptive extraction (SBSE) has been developed in 1999 to efficiently extract and preconcentrate volatile compounds, and many applications have been found after that. This technique conforms to the principles of green chemistry. Here, we used an autosampler with an online thermal desorption unit connected to CGC-MS to analyze pesticides. This study describes the development of a highly sensitive
-
A study on the bacterial adhesion of Streptococcus mutans in various dental ceramics: In vitro study Open Chem. (IF 1.216) Pub Date : 2020-11-04 Fuat Bislimi; Jagoda Bajevska; Mrinmoy Garai; Arianit A. Reka
Streptococcus mutans (S. mutans) has been identified as a major etiologic agent of human dental caries and forms a significant proportion of oral streptococci in carious lesions. This study investigates the correlation of surface properties (effect of contact angle [CA] and free surface energy) on three restorative materials (zirconia, nickel–chromium–molybdenum alloy and composites) used in dental
-
An improved reduction method for phase stability testing in the single-phase region Open Chem. (IF 1.216) Pub Date : 2020-11-05 Dan Vladimir Nichita; Catinca Secuianu
A new reduction method for mixture phase stability testing is proposed, consisting in Newton iterations with a particular set of independent variables and residual functions. The dimension of the problem does not depend on the number of components but on the number of components with nonzero binary interaction parameters in the equation of state. Numerical experiments show an improved convergence behavior
-
Synthesis and efficacy of herbicidal ionic liquids with chlorsulfuron as the anion Open Chem. (IF 1.216) Pub Date : 2020-10-13 Marcin Praczyk; Katarzyna Wielgusz; Witold Stachowiak; Michał Niemczak; Juliusz Pernak
In the framework of this research, four new herbicidal ionic liquids (HILs) comprising chlorsulfuron as the anion were synthesized and characterized. The new salts with chlorsulfuron contained the following cations: tetramethylammonium, didecyldimethylammonium, benzyltrimethylammonium and cholinium. All products were obtained with high yields exceeding 90% via acid–base reaction or ion exchange reaction
-
Comparative analysis of chemical composition of some commercially important fishes with an emphasis on various Malaysian diets Open Chem. (IF 1.216) Pub Date : 2020-10-20 Mustafizur M. Rahman; Siti Hajar; Kamaruzzaman B. Yunus
This study compares the chemical composition of cockle (Anadara granosa) and some commercially important marine (Asian seabass Lates calcarifer, grouper Epinephelus bleekeri, hardtail scad Megalaspis cordyla, longtail tuna Thunnus tonggol and Indian mackerel Rastrelliger kanagurta) and freshwater (sutchi catfish Pangasius hypophthalmus, Nile tilapia Oreochromis niloticus and eel Monopterus albus) fishes
-
Synthesis, spectral and thermo-kinetics explorations of Schiff-base derived metal complexes Open Chem. (IF 1.216) Pub Date : 2020-10-20 Naushad Ahmad; Manawwer Alam; Rizwan Wahab; Mukhtar Ahmed; Ashfaq Ahmad
Schiff-base ligand, 2,6-bis(benzimino)-4-phenyl-1,3,5-triazine (L), and its transition metal complexes of Co(ii), Ni(ii), and Cu(ii) were synthesized by refluxing the reaction mixture and its analytical, spectral, and thermogravimetric characteristics were explored by various techniques: AAS, FT-IR, UV-vis, TG-DTG, CHNS/O, and VSM. It was observed that all the metal containing complexes are non-electrolytic
-
Effect of isovalent substitution on the crystal structure and properties of two-slab indates BaLa2−xSmxIn2O7 Open Chem. (IF 1.216) Pub Date : 2020-10-20 Yuri Titov; Nadezhda Belyavina; Mykola Slobodyanik; Olesya Nakonechna; Nataliia Strutynska; Mariana Tymoshenko
Exploring the effect of isomorphic substitution of atoms on crystal structure and features of oxide compounds is one of the main tasks of modern materials science. This paper deals with the La/Sm isovalent substitution in a two-slab perovskite-like BaLa2In2O7 structure and its effect on the structural features and magnetic properties of BaLa2−xSmxIn2O7 indates synthesized. A complete characterization
-
A promising naphthoquinone [8-hydroxy-2-(2-thienylcarbonyl)naphtho[2,3-b]thiophene-4,9-dione] exerts anti-colorectal cancer activity through ferroptosis and inhibition of MAPK signaling pathway based on RNA sequencing Open Chem. (IF 1.216) Pub Date : 2020-10-20 Daneiva Caro; David Rivera; Yanet Ocampo; Klaus Müller; Luis A. Franco
Naphthoquinones are naturally occurring metabolites with recognized anti-cancer potential but limited clinical application. This study investigated the molecular mechanism of 8-hydroxy-2-(2-thenoyl)naphtho[2,3-b]thiophene-4,9-dione (1), a new candidate for colorectal cancer (CRC) treatment, using different experimental settings: MTT, clonogenic, wound healing, and cell cycle assays; as well as RNA
-
Plant description, phytochemical constituents and bioactivities of Syzygium genus: A review Open Chem. (IF 1.216) Pub Date : 2020-10-13 Ei Ei Aung; Alfinda Novi Kristanti; Nanik Siti Aminah; Yoshiaki Takaya; Rico Ramadhan
This article attempts to report native growth, plant description, phytochemical constituents and bioactivities of Syzygium aqueum, S. aromaticum, S. cumini, S. guineense and S. samarangense. Those are the large public species in the Syzygium genus and some of them have been used as traditional medicines. Different parts (leaves, seeds, fruits, barks, stem barks and flower buds) of each species plant
-
Antioxidant activity as a response to cadmium pollution in three durum wheat genotypes differing in salt-tolerance Open Chem. (IF 1.216) Pub Date : 2020-09-29 Jakub Pastuszak; Przemysław Kopeć; Agnieszka Płażek; Krzysztof Gondek; Anna Szczerba; Marta Hornyák; Franciszek Dubert
Durum wheat is commonly used in various food industry industries and cultivated worldwide. A serious problem with the species cultivation is its capability to accumulate cadmium (Cd) in the grains. The aim of this study is to investigate whether antioxidant activity may be used as a marker of Cd tolerance in durum wheat. The experiment involved three durum wheat genotypes/lines differing in salt tolerance
-
Amine-functionalized magnetic activated carbon as an adsorbent for preconcentration and determination of acidic drugs in environmental water samples using HPLC-DAD Open Chem. (IF 1.216) Pub Date : 2020-09-29 Mpingana Ndilimeke Akawa; Kgogobi Mogolodi Dimpe; Philiswa Nosizo Nomngongo
In the present study, a convenient and highly effective method was developed for the quantification of acidic drugs in wastewater and river water samples. Ultrasonic-assisted magnetic solid phase extraction employing magnetic waste tyre-based activated carbon nanocomposite functionalized with [3-(2-aminoethylamino)propyl]trimethoxysilane as a cost-effective and efficient adsorbent was used for the
-
Erratum to: A one-step incubation ELISA kit for rapid determination of dibutyl phthalate in water, beverage and liquor Open Chem. (IF 1.216) Pub Date : 2020-09-26 Qing Sun; Yanli Chen; Fuxue Li; Minghong Jia; Guoqing Shi
Journal Name: Open Chemistry Volume: 18 Issue: 1 Pages: 1217-1217
-
Mesoscale nanoparticles encapsulated with emodin for targeting antifibrosis in animal models Open Chem. (IF 1.216) Pub Date : 2020-09-26 Lishan Tan; Xiulong Deng; Xuandi Lai; Tao Zeng; Aiqing Li; Jianqiang Hu; Zuying Xiong
The aim of this study is to explore the kidney-targeting capability of mesoscale nanoparticles (MNPs)-emodin (Em-MNPs) and its potential antifibrosis in the animal model. First, MNPs and Em-MNPs were synthesized via nanoprecipitation method, and their diameters were both ∼400 nm with the uniform size. The entrapment efficiency of MNPs was 45.1% when adding emodin at the concentration of 12 mg/mL. Moreover
-
Structure and some physicochemical and functional properties of water treated under ammonia with low-temperature low-pressure glow plasma of low frequency Open Chem. (IF 1.216) Pub Date : 2020-09-26 Aleksandra Ciesielska; Wojciech Ciesielski; Henryk Kołoczek; Damian Kulawik; Joanna Kończyk; Zdzislaw Oszczęda; Piotr Tomasik
Deionized, tap and two kinds of commercially available mineralized water, after supplementation with ammonia, were treated with low-pressure, low-temperature glow plasma (GP) of low frequency. Treating hard water with ammonia provided the removal of permanent and temporary water hardness already at room temperature. On such treatment, mineralized water supplemented with ammonia was partly demineralized
-
The degradation, biodegradability and toxicity evaluation of sulfamethazine antibiotics by gamma radiation Open Chem. (IF 1.216) Pub Date : 2020-09-26 Yuankun Liu; Jianlong Wang; Zhiwei Zhou; Xiaoying Zheng; Liyuan Zhao; Aixin Yu
This study evaluated gamma radiation-enhanced sulfamethazine (SMT) degradation, which belongs to the heterocyclic sulfonamides, in different conditions in aqueous solution. The results showed that gamma irradiation could increase the SMT removal in aqueous solution, and the SMT degradation kinetic follow the modified pseudo-first-order kinetic. The degradation rate was nearly 95% at the absorbed dose
-
Concentrations of dioxins, furans and dioxin-like PCBs in natural animal feed additives Open Chem. (IF 1.216) Pub Date : 2020-09-26 Mateusz Ossowski; Łukasz Wlazło; Bożena Nowakowicz-Dębek; Anna Chmielowiec-Korzeniowska; Hanna Bis-Wencel
The study aimed to assess the concentration of dioxins, furans, and dioxin-like polychlorinated biphenyls (PCBs) in natural feed additives used in animal nutrition. The research material consisted of four natural sorbents used as feed additives registered in the EU. The samples were analysed for the content of six octachlorodibenzo-p-dioxins (OCDDs) congeners, nine octachlorodibenzofurans (OCDFs) and
-
MALDI-TOF MS profiling in the discovery and identification of salivary proteomic patterns of temporomandibular joint disorders Open Chem. (IF 1.216) Pub Date : 2020-09-21 Galina Laputková; Ivan Talian; Vladimíra Schwartzová; Zuzana Schwartzová
This research aimed to identify differences in polypeptide/protein profiles of the unstimulated whole saliva between patients with temporomandibular joint disorders (TMDs) and healthy individuals. A fraction of the polypeptides/proteins (<30 kDa) was analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. The spectra were recovered from methanoic acid/acetonitrile
-
Omega and the related counting polynomials of some chemical structures Open Chem. (IF 1.216) Pub Date : 2020-09-14 Wei Gao; Saad Ihsan Butt; Muhammad Numan; Adnan Aslam; Zeeshan Malik; Muhammad Waqas
Counting polynomials are mathematical functions having as coefficients the multiplicity of property partition and as exponent the extent of the corresponding partition. In this work, four counting polynomials are computed: omega, theta, sadhana, and Padmakar–Ivan (PI) polynomials of benzene ring embedded in the P-type surface on 2-D network and n-phenylene. Moreover, the closed formulas of the corresponding
-
The combined use of GC, PDSC and FT-IR techniques to characterize fat extracted from commercial complete dry pet food for adult cats Open Chem. (IF 1.216) Pub Date : 2020-09-11 Klara Zglińska; Tomasz Niemiec; Joanna Bryś; Andrzej Bryś; Andrzej Łozicki; Iwona Kosieradzka; Piotr Koczoń
This study aims to compare the quality of fat extracted from different priced dry pet food for adult cats through classical and instrumental methods: pressure differential scanning calorimetry (PDSC), Fourier transform infrared spectroscopy (FT-IR) or gas chromatography (GC). Fat extracted from pet food was examined for induction time (IT), fatty acid composition, free fatty acid (FFA) content and
-
Magnetic iron oxide/clay nanocomposites for adsorption and catalytic oxidation in water treatment applications Open Chem. (IF 1.216) Pub Date : 2020-09-08 Ganjar Fadillah; Septian Perwira Yudha; Suresh Sagadevan; Is Fatimah; Oki Muraza
Physical and chemical methods have been developed for water and wastewater treatments. Adsorption is an attractive method due to its simplicity and low cost, and it has been widely employed in industrial treatment. In advanced schemes, chemical oxidation and photocatalytic oxidation have been recognized as effective methods for wastewater-containing organic compounds. The use of magnetic iron oxide
-
Polyphenol content and antioxidant activities of Prunus padus L. and Prunus serotina L. leaves: Electrochemical and spectrophotometric approach and their antimicrobial properties Open Chem. (IF 1.216) Pub Date : 2020-09-08 Aleksandra Telichowska; Joanna Kobus-Cisowska; Marta Ligaj; Kinga Stuper-Szablewska; Daria Szymanowska; Mariusz Tichoniuk; Piotr Szulc
The aim of the study was to compare the content of selected phytochemicals as well as the antioxidant and antimicrobial potential of the leaves of Prunus padus L. and Prunus serotina L., as there is very little research on this subject in the literature. Therefore, it is used to deepen knowledge on this subject. In addition, an electrochemical test was also carried out, which was not yet available
-
Fluorescence in the assessment of the share of a key component in the mixing of feed Open Chem. (IF 1.216) Pub Date : 2020-08-26 Dominika Barbara Matuszek
This paper presents the results of the mixing of a multicomponent feed for cattle. Three types of mixtures with different proportions of individual components and granulometric composition were selected. After the mixing process, the fraction of the key component (tracer) was determined. Tracer consisted of crushed grains of yellow maize, which was wet treated with a 0.01% solution of Rhodamine B.
-
Multivariate analysis for the classification of copper–lead and copper–zinc glasses Open Chem. (IF 1.216) Pub Date : 2020-08-26 Dimitar Dimitrov; Miroslava Nedyalkova; Sergio Madurga; Ludmila Naneva; Vasil Simeonov
The similarity patterns in the physicochemical properties of copper–lead and copper–zinc borate glasses were identified by means of finding similarity within the objects of study using multivariate statistical analysis. As exploratory methods of multivariate analysis, cluster analysis, principal components analysis, and two-way clustering were applied for a set of copper–lead and copper–zinc borate
-
The spatial and temporal distribution of cationic and anionic radicals in early embryo implantation Open Chem. (IF 1.216) Pub Date : 2020-08-26 Zhikun Bai
The main objective of this study is to obtain some knowledge of cationic and anionic radicals in early embryo implantation in mice. The method used in this study is known as histochemical staining, in which Xylidine ponceau was used at pH 2.5 and toluidine blue was used at pH 4.0. We detected the change in glycosaminoglycans and total proteins in the endometrial stroma during the preimplantation of
-
Preparation of a novel ginkgolide B niosomal composite drug Open Chem. (IF 1.216) Pub Date : 2020-08-26 Juntong Zhou; Xiao Wu; Zhanhong Zhao; Zhenpeng Wang; Shumu Li; Chang Chen; Shan Yu; Xintong Qu; Kexin Li; Ye Tian; Xiaojing Liu; Gaoyu Zhang; Zhaoxuan Wang; Chi Li; Ning Kang; Qing Huo
Ginkgolide B (GB) and Puerarin (Pue) are active pharmaceutical ingredients for the treatment of Parkinson’s disease (PD); however, both are poorly water-soluble, which limits their bioavailability. The present study used the niosome vesicle encapsulation technique to prepare a novel GB composite drug. The conditions for GB–Pue niosomal complex preparation were as follows: a hydration temperature of
-
A Zn(ii)–organic cage with semirigid ligand for solvent-free cyanosilylation and inhibitory effect on ovarian cancer cell migration and invasion ability via regulating mi-RNA16 expression Open Chem. (IF 1.216) Pub Date : 2020-08-29 Yan Yin; Hong Mai; Li-Ying Zhang; Yan Liao; Xu-Peng Liu; Ye-Ping Wei
[Zn6(L)4(DMF)2(H2O)4](1,4-Dioxane)2(DMF)10(H2O)4 (1, L = 4,4′,4″-(benzene-1,3,5-triyltris(oxy))tribenzoate), the metal-organic cage, was produced via Zn(NO3)2·6H2O reacting with the H3L ligand in the mixed solvent of DMF and water. The heterogeneous catalytic activities of the complex 1 for the aldehydes cyanidation under the conditions of free solvent were studied, which indicates that the removal
-
A Dy(iii)–organic framework as a fluorescent probe for highly selective detection of picric acid and treatment activity on human lung cancer cells Open Chem. (IF 1.216) Pub Date : 2020-08-29 Shi-Jie Fan; Ren Sun; Yu-Bo Yan; Hao-Bo Sun; Sai-Nan Pang; Shi-Dong Xu
A dysprosium(iii) organic framework, {[Dy(H2O)(BTCTB)]·2H2O}n (1, H3BTCTB = 3,3′,3′′-[1,3,5-benzenetriyltris(carbonylimino)]tris-benzoic acid), was synthesized through the hydrothermal reaction of Dy(NO3)3 with the C3-symmetric organic ligand H3BTCTB at 160°C for 96 h. At the same time, the sensitivity of picric acid in water medium was tested with material 1 as the fluorescent sensor. The detection
-
Sulfur application alleviates chromium stress in maize and wheat Open Chem. (IF 1.216) Pub Date : 2020-08-29 Grzegorz Kulczycki; Elżbieta Sacała
This study aimed to examine the influence of increasing doses of chromium (Cr) (26, 39, and 52 mg kg−1 soil) and elemental sulfur (S) (60 mg kg−1 soil) on growth, yield, and mineral nutrition in wheat and maize. Macro- and micronutrients and Cr concentrations were determined in the aboveground parts of plants. All examined doses of Cr caused a marked decrease in the fresh and dry weight of maize. Wheat
-
Electrochemical evaluation of the antioxidant capacity of natural compounds on glassy carbon electrode modified with guanine-, polythionine-, and nitrogen-doped graphene Open Chem. (IF 1.216) Pub Date : 2020-08-19 Yafen Fu; Zongyi You; Aiping Xiao; Liangliang Liu; Weien Zhou
An electrochemical sensor based on guanine-, polythionine-, and nitrogen-doped graphene modified glassy carbon electrode (G/PTH/NG/GCE) was fabricated and applied for antioxidant capacity evaluation of natural compounds and complexes in electrochemical method since natural sources of active compounds exhibited various antioxidant activities. When the antioxidants existed in the system, the generated
-
Composition and diurnal variation of floral scent emission in Rosa rugosa Thunb. and Tulipa gesneriana L. Open Chem. (IF 1.216) Pub Date : 2020-08-14 Lu Yang; Xiang Liao; Ping Cheng; Zhi-Gang Zhang; Hong Li
This study was aimed to explore the composition and diurnal variation analyses of floral scent emission from Rosa rugosa Thunb. and Tulipa gesneriana L. The floral scent from the fresh flower were collected at different time points (9:00, 12:00, 15:00, 18:00, and 21:00) using dynamic headspace collection and were analyzed using autothermal desorber-gas chromatography/mass spectrometry (ATD-GC/MS).
-
Diabetes mellitus type 2: Exploratory data analysis based on clinical reading Open Chem. (IF 1.216) Pub Date : 2020-08-11 Miroslava Nedyalkova; Sergio Madurga; Davide Ballabio; Ralitsa Robeva; Julia Romanova; Ilia Kichev; Atanaska Elenkova; Vasil Simeonov
Diabetes mellitus type 2 (DMT2) is a severe and complex health problem. It is the most common type of diabetes. DMT2 is a chronic metabolic disorder that affects the way your body metabolizes sugar. With DMT2, your body either resists the effects of insulin or does not produce sufficient insulin to continue normal glucose levels. DMT2 is a disease that requires a multifactorial approach of controlling
-
Development of trace analysis for alkyl methanesulfonates in the delgocitinib drug substance using GC-FID and liquid–liquid extraction with ionic liquid Open Chem. (IF 1.216) Pub Date : 2020-08-11 Shinkichi Nomura; Yoshiharu Ito; Shigehiko Takegami; Tatsuya Kitade
Alkyl methanesulfonates are genotoxic impurities that should be limited to an intake of not more than 1.5 µg/day, as regulated by the International Council for Harmonization guideline M7. We herein report a trace analysis of methyl methanesulfonate (MMS), ethyl methanesulfonate (EMS), and isopropyl methanesulfonate (IPMS) in the delgocitinib drug substance using liquid–liquid extraction, with an ionic
-
A novel lactose biosensor based on electrochemically synthesized 3,4-ethylenedioxythiophene/thiophene (EDOT/Th) copolymer Open Chem. (IF 1.216) Pub Date : 2020-08-11 Songul Sen Gursoy; Abdulkerim Yildiz; Gamze Celik Cogal; Oguz Gursoy
In this study, a new lactose biosensor has been developed in which the 3,4-ethylenedioxythiophene/thiophene (EDOT/Th) copolymer is used as a transducer. The EDOT/Th copolymer was deposited on the glassy carbon electrode to be used as the working electrode. In addition to the working electrode, the three-electrode system was used in both the electrochemical synthesis and in the biosensor measurements
-
DFT investigations on arylsulphonyl pyrazole derivatives as potential ligands of selected kinases Open Chem. (IF 1.216) Pub Date : 2020-08-03 Kornelia Czaja; Jacek Kujawski; Radosław Kujawski; Marek K. Bernard
Using the density functional theory (DFT) formalism, we have investigated the properties of some arylsulphonyl indazole derivatives that we studied previously for their biological activity and susceptibility to interactions of azoles. This study includes the following physicochemical properties of these derivatives: electronegativity and polarisability (Mulliken charges, adjusted charge partitioning
-
PCSK9 concentrations in different stages of subclinical atherosclerosis and theisr relationship with inflammation Open Chem. (IF 1.216) Pub Date : 2020-08-07 Štefan Tóth; Peter Olexa; Zdenka Hertelyová; Peter Štefanič; Ivan Kopolovets; Peter Berek; Vladimir Filip; Ryan Chakravarty; Monika Široká; Daniel Pella
The aim of this study was to detect the concentrations of PCSK9 in various subclinical stages of atherosclerosis and to highlight its relationship with inflammation. One hundred and fifty-nine healthy patients were divided into three groups, based on the extent of atherosclerotic changes in the carotid artery: a group without identifiable atherosclerosis, cIMT>75‰ and an asymptomatic plaque group.
-
Development and validation of a high performance liquid chromatography/diode array detection method for estrogen determination: Application to residual analysis in meat products Open Chem. (IF 1.216) Pub Date : 2020-08-07 Sadeem S. Alqahtani; Deema M. Bin Humaid; Sabreen H. Alshail; Dalal T. AlShammari; Hessa Al-Showiman; Nourah Z. Alzoman; Hadir M. Maher
In this work, an HPLC-DAD method was developed for the residual analysis of some estrogens such as estrone (E1), 17-β estradiol (E2), estriol (E3), natural estrogens, and 17-α ethinylestradiol (E4), an exoestrogen, in meat samples of different categories (chicken, n = 155, beef, n = 124, sheep, n = 122, and camels, n = 40), collected from the Saudi Market. Although banned, the use of E4 as a growth
-
Citrullus colocynthis (L.) Schrad: Chemical characterization, scavenging and cytotoxic activities Open Chem. (IF 1.216) Pub Date : 2020-08-07 Mohammed Bourhia; Mouhcine Messaoudi; Hanane Bakrim; Ramzi A. Mothana; Nasir A. Sddiqui; Omer M. Almarfadi; Mohammed El Mzibri; Said Gmouh; Amin Laglaoui; Laila Benbacer
Citrullus colocynthis (L.) Schrad (C. colocynthis) called colocynth is a wild species that belongs to the family cucurbitaceae. The present research work aimed to study the phytochemical composition, cytotoxic and antioxidant activities of C. colocynthis seed extract. The chemical characterization of C. colocynthis seeds was effectuated using a gas chromatograph coupled to a mass spectrometer (GC-MS)
-
Stability-indicating HPLC-DAD assay for simultaneous quantification of hydrocortisone 21 acetate, dexamethasone, and fluocinolone acetonide in cosmetics Open Chem. (IF 1.216) Pub Date : 2020-08-07 Saira Arif; Sadia Ata
A rapid and specific method was developed for simultaneous quantification of hydrocortisone 21 acetate (HCA), dexamethasone (DEX), and fluocinolone acetonide (FCA) in whitening cream formulations using reversed-phase high-performance liquid chromatography. The effect of the composition of the mobile phase, analysis temperature, and detection wavelength was investigated to optimize the separation of
-
Synthesis of magnesium carbonate hydrate from natural talc Open Chem. (IF 1.216) Pub Date : 2020-08-07 Qiuju Chen; Tao Hui; Hongjuan Sun; Tongjiang Peng; Wenjin Ding
Various morphologies of magnesium carbonate hydrate had been synthesized without using any organic additives by carefully adjusting the reaction temperature and time during the talc carbonation process. At lower temperatures, magnesium carbonate hydrate was prone to display needle-like morphology. With the further increase of the carbonation temperature, the sheet-like crystallites became the preferred
-
Design, synthesis and pharmacological profile of (−)-verbenone hydrazones Open Chem. (IF 1.216) Pub Date : 2020-08-07 Mariia Nesterkina; Dmytro Barbalat; Iryna Kravchenko
A series of novel (−)-verbenone hydrazones was designed and synthesized via condensation of terpenoid with hydrazides derived from phenoxyacetic acid. The structure of target compounds was confirmed by 1H-NMR and 13C-NMR analysis, Raman and FT-IR spectroscopy, electrospray ionization method and fast atom bombardment (FAB) mass spectrometry. Thermal properties of (−)-verbenone hydrazones 3a–3e were
-
A theoretical and experimental study of the adsorptive removal of hexavalent chromium ions using graphene oxide as an adsorbent Open Chem. (IF 1.216) Pub Date : 2020-08-07 Ardhmeri Alija; Drinisa Gashi; Rilinda Plakaj; Admir Omaj; Veprim Thaçi; Arianit Reka; Sefer Avdiaj; Avni Berisha
This study is focused on the adsorption of hexavalent chromium ions Cr(vi) using graphene oxide (GO). The GO was prepared by chemical oxidation (Hummers method) of graphite particles. The synthesized GO adsorbent was characterized by Fourier transform infrared spectroscopy and UV-Vis spectroscopy. It was used for the adsorption of Cr(vi) ions. The theoretical calculations based on density functional
-
Withania frutescens: Chemical characterization, analgesic, anti-inflammatory, and healing activities Open Chem. (IF 1.216) Pub Date : 2020-08-07 Abdelfattah EL Moussaoui; Fatima Zahra Jawhari; Mohammed Bourhia; Imane Maliki; Fatiha Sounni; Ramzi A. Mothana; Dalila Bousta; Amina Bari
Withania frutescens (W. frutescens) is a medicinal plant that is largely used in the Morrocan pharmacopeia for disease treatment. This work was conducted to investigate the chemical characterization, analgesic, anti-inflammatory, and healing activities of W. frutescens. The chemical characterization of W. frutescens extract was done using HPLC; the anti-inflammatory test was performed with doses 300
-
Fluorescence biomarkers of malignant melanoma detectable in urine Open Chem. (IF 1.216) Pub Date : 2020-08-07 Ivana Špaková; Katarína Dubayová; Vladimíra Nagyová; Mária Mareková
Malignant melanoma (MM) is a cancerous transformation of melanocytes. It is a disease with the worst response to therapy and, compared to other malignancies, presents much earlier with metastases. MM still belongs to relatively late-detected malignant diseases. Even so, the MM mortality rate is up to 96% for a relatively small incidence (5%). The gold standard for MM diagnosis is a histopathological
-
Optimisation of urine sample preparation for shotgun proteomics Open Chem. (IF 1.216) Pub Date : 2020-08-07 Soňa Tkáčiková; Ivan Talian; Ján Sabo
Urine reflects the renal function and urinary and kidney systems, but it may also reflect the presence of cancer in other parts of the body. Urine also has potential for providing prognostic information during therapeutic treatments thanks to non-invasive monitoring. A quick and reproducible protein purification procedure is essential to allow data comparison between proteomic studies in urine biomarker
Contents have been reproduced by permission of the publishers.