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Anticancer and Antimicrobial Activity of Some New 2,3-Dihydro-1,5-benzodiazepine Derivatives Heteroat. Chem. (IF 0.3) Pub Date : 2023-11-6 Felix Odame, Tatenda Madanhire, Clement Tettey, David Neglo, Francisca Adzaho, Daniel Sedohia, Eric C. Hosten
A series of 2,3-dihydro-1,5-benzodiazepine derivatives have been synthesized and characterized using IR, NMR, GC-MS, single crystal XRD, and microanalysis. The results of their antibacterial activity against methicillin-resistance Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, Streptococcus mutans, Pseudomonas aeruginosa, Salmonella typhi, and Streptococcus pyrogens
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Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities Heteroat. Chem. (IF 0.3) Pub Date : 2023-2-9 Ngoc Hung Truong, Thi Hong Ha Tran, Kim Chi Hoang, Duc Bao Ninh, Viet Duc Le, Duc Anh Le, Van Chinh Luu
Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification and S-alkylation. Analysis of the NMR spectral data indicated that the dimer of DHA with thiols 6-mercaptopurine and 2-mercaptoimidazole was produced with yields of 31% and 62%, respectively. Furthermore, the tautomerization
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Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one Heteroat. Chem. (IF 0.3) Pub Date : 2023-2-4 Quang Trung Nguyen, Phuong Nam Pham Thi, Quang Do Bui, Van Tuyen Nguyen
An unsymmetrical salen-type Schiff base ligand, (Z)-1-(((2-((E)-(2-hydroxy-6-methoxybenzylidene)amino)phenyl)amino)methylene)naphthalen-2(1H)-one, and its Zn(II), Cu(II), Co(II), Mn(II), and Fe(III) complexes were synthesized and characterized by mass (MS), nuclear magnetic resonance (NMR), infrared (IR), ultraviolet-visible (UV-Vis) spectra, and effective magnetic moments. The thermal analyses of
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Synthesized Phosphonium Compounds Demonstrate Resistant Modulatory and Antibiofilm Formation Activities against Some Pathogenic Bacteria Heteroat. Chem. (IF 0.3) Pub Date : 2022-9-26 Cedric Dzidzor Kodjo Amengor, Cynthia Amaning Danquah, Emmanuel Bentil Asare Adusei, Francis Klenam Kekessie, Francis Ofosu-Koranteng, Paul Peprah, Benjamin Kingsley Harley, Emmanuel Orman, Joseph Adu, Yussif Saaka
A library of six compounds with new hybrids in a single molecule triazole ring attached to the phosphonium salts was synthesized. Click chemistry was, however, used to synthesize the 1-, 2-, and 3-triazole intermediates as a tether for the hybrid phosphonium salts. Their antibacterial activity against Gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis), Gram-negative bacteria (Escherichia
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Synthesis, Structure, and Antifungal Activities of 3-(Difluoromethyl)-Pyrazole-4-Carboxylic Oxime Ester Derivatives Heteroat. Chem. (IF 0.3) Pub Date : 2022-08-28 Bin Wang, Wei-Ting Chen, Li-Jing Min, Liang Han, Na-Bo Sun, Xing-Hai Liu
Fifteen new pyrazole-4-carboxylic oxime ester derivatives were conveniently synthesized, and their structures were confirmed by 1H NMR, 13C NMR, HRMS, and X-ray diffraction. Antifungal assays indicated that some of these compounds possessed good activity against S. sclerotiorum, B. cinerea, R. solani, P. oryae, and P. piricola at 50 ppm. Structure-activity relationships (SAR) were studied by molecular
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Isolation, Synthesis, and Fungicidal Activity of Isopropyl (3-methyl-1-oxo-1-((1-((4-(prop-2-yn-1-yloxy)phenyl)thio)propan-2-yl)amino)butan-2-yl)carbamate Diastereomers against Phytophthora capsici Heteroat. Chem. (IF 0.3) Pub Date : 2022-08-05 Lei Tian, Yang Gao, Xing-Jie Peng, Cheng Zhang, Wei-Guang Zhao, Xing-Hai Liu
Two isopropyl (3-methyl-1-oxo-1-((1-((4-(prop-2-yn-1-yloxy)phenyl)thio)propan-2-yl)amino)butan-2-yl)carbamate diastereomers were isolated. Fungicidal activities indicated that the isolated four chiral compounds possessed excellent activity against P. capsici with the EC50 value of 4a (1.30 μg/mL), 4b (0.078 μg/mL), 4c (1.85 μg/mL), and 4d (44.4 μg/mL). Among them, compound 4b exhibited remarkably high
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Triazoles Synthesis & Applications as Nonsteroidal Aromatase Inhibitors for Hormone-Dependent Breast Cancer Treatment Heteroat. Chem. (IF 0.3) Pub Date : 2022-04-28 Huda R. M. Rashdan, Ihsan A. Shehadi
In the last few years, nonsteroidal aromatase inhibitors (AIs) have been emerged as promising agents for treating hormone-dependent breast cancer in postmenopausal women because of their inhibitory effect on estrogen synthesis. Indeed, these compounds can block the activity of aromatase, the enzyme that intervenes in the last steps of estrogen production pathway. Triazoles are the core structures of
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Reexamining Povarov Reaction’s Scope and Limitation in the Generation of HCV-NS4A Peptidomimetics Heteroat. Chem. (IF 0.3) Pub Date : 2022-02-10 Maan T. Khayat, Abdelsattar M. Omar, Mahmoud A. Elfaky, Yosra A. Muhammad, Elaf A. Felemban, Khalid M. El-Say, Moustafa E. El-Araby
Chronic Hepatitis C is a global health threat and a silent killer. Regardless of the profound progress in preventing and treating this disease, research continues to discover new direct antiviral agents (DAAs), especially against novel targets. Our research has been directed to leverage the NS4A binding site to develop peptidomimetic inhibitors of the hepatitis C virus (HCV) NS3 protease. In previous
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Cyclization Reactions Involving 2-Aminoarenetellurols and Derivatives of α,β-Unsaturated Carboxylic Acids Heteroat. Chem. (IF 0.3) Pub Date : 2021-12-22 Jayna A. Patel, Aundrea M. Lee, Donna V. Franklin, Frank R. Fronczek, Thomas Junk
The reductive cyclization of arenetellurols carrying α,β-unsaturated amide functionalities in the ortho position was investigated. Conceptually, such compounds can form 1,3-tellurazoles without the involvement of the unsaturation in the ring closure, they can form 1,4-tellurazinone derivatives, or they can undergo ring closure to 1,5-tellurazepinones. Amides derived from acrylic and methacrylic acid
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A Remarkably Efficient Phase-Transfer Catalyzed Amination of α-Bromo-α, β-Unsaturated Ketones in Water Heteroat. Chem. (IF 0.3) Pub Date : 2021-01-04 Alemayehu Mekonnen, Alemu Tesfaye
Tandem conjugate addition–alkylation reaction of various amines with α-bromo-α, β-unsaturated ketones resulted in near-quantitative conversions into the corresponding aziridines when the reaction was carried out in the presence of 10 mol% of phase-transfer, PT catalysts in water. Some chiral quaternary ammonium salts derived from Cinchona alkaloids were investigated as water-stable PT catalysts. The
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Understanding the Mechanism and Selectivities of the Reaction of Meta-Chloroperbenzoic Acid and Dibromocarbene with β-Himachalene: A DFT Study Heteroat. Chem. (IF 0.3) Pub Date : 2020-09-18 Sana El Hamidi, Malika Khnifira, El Mokhtar Lemdek, Redouan Hammal, Noureddine Barka, M’hamed Sadiq, Ahmed Benharref, Ahmed Chekroun, Hssaine Zgou, Mohamed Abdennouri
This study was performed to understand the site selectivity in the reaction between β-himachalene and meta-chloroperbenzoic acid (m-CPBA) in the first step followed by the addition of dibromocarbene (CBr2) to the main monoepoxidation product Pα formed in the first reaction. Calculations were performed using the Becke three-parameter hybrid exchange functional and the Lee–Yang–Parr correlation functional
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Synthesis of Some Novel Fluorinated/Nonfluorinated α-Amino Acids, Bearing 3-Thioxo-5-oxo-1,2,4-triazin-6-yl and Steroidal Moieties, and Evaluation of Their Amylolytic Effects against Some Fungi, Part-II Heteroat. Chem. (IF 0.3) Pub Date : 2020-07-23 Reda M. Abdel-Rahman, Wafa A. Bawazir
Some new fluorinated/nonfluorinated α-amino acids bearing 3-thioxo-5-oxo-1,2,4-triazin-6-yl and steroidal moieties have been obtained from condensation of the corresponding amino-triazinones with the steroid (Epiandrosterone). This was followed by the addition of HCN and, finally, acidic hydrolysis. The structure of the targets was established from their elemental analysis and spectral data. The amylolytic
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Synthesis of Organic Ligands via Reactions of 4-Benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione with N-Nucleophiles Heteroat. Chem. (IF 0.3) Pub Date : 2020-07-08 Hassan Kabirifard, Pardis Hafez Taghva, Hossein Teimouri, Niloofar Koosheshi, Parastoo Javadpour, Hanieh Bagherinejad, Soheila Seyfi, Maryam Hossein Roodbari, Elaheh Golabian
The reaction of 4-benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione (1) with aminoheteroaryls, lamotrigine, 1,3-diaminoheteroaryls, dapsone, NH2R (hydroxylamine, DL-1-phenylethylamine, and metformin), and 4,4′-bipyridine in THF/H2O (1 : 1) at room temperature led to 3-N-phenylthiocarbamoyl-2-butenamides 2–5, while that with naphthylamines and 1,3-phenylenediamine in ethanol at high temperature led
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Efficient ZrO(NO3)2.2H2O Catalyzed Synthesis of 1H-Indazolo[1,2-b] phthalazine-1,6,11(13H)-triones and Electronic Properties Analyses, Vibrational Frequencies, NMR Chemical Shift Analysis, MEP: A DFT Study Heteroat. Chem. (IF 0.3) Pub Date : 2020-03-01 Forozan Piryaei, Nahid Shajari, Hooriye Yahyaei
The synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11(13H)-trione derivatives, using one-pot three-component condensation reaction of 3-nitrophthalic anhydride, hydrazine monohydrate, dimedone, and aromatic aldehydes in the presence of ZrO(NO3)2.2H2O as the novel catalyst and in reflux conditions in EtOH was reported. Quantum theoretical calculations for three structures of compounds (5a, 5b, and 5c)
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Dichlorophosphoranides Stabilized by Formamidinium Substituents Heteroat. Chem. (IF 0.3) Pub Date : 2020-02-13 Anatoliy Marchenko, Georgyi Koidan, Anastasiya Hurieva, Eduard Rusanov, Alexander B. Rozhenko, Aleksandr Kostyuk
Dichlorophosphoranides featuring N,N-dimethyl-N′-arylformamidine substituents were isolated as individual compounds. Dichlorophosphoranide 9 was prepared by the multicomponent reaction of C-trimethylsilyl-N,N-dimethyl-N′-phenylformamidine and N,N-dimethyl-N′-phenylformamidine with phosphorus trichloride. Its molecular structure derived from a single-crystal X-ray diffraction was compared to the analogous
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Synthesis of New Oxindoles and Determination of Their Antibacterial Properties Heteroat. Chem. (IF 0.3) Pub Date : 2020-02-08 Pablo E. Romo, Braulio Insuasty, Rodrigo Abonia, María del Pilar Crespo, Jairo Quiroga
A versatile method for the synthesis of new oxindoles was developed by the reaction between substituted isatins and 5-aminopyrazoles. The reaction was carried out at room temperature in ethanol using p-toluenesulfonic acid as the catalyst. The products were obtained with acceptable to excellent yields (44–96%). Structures of the new compounds were unambiguously established by spectroscopic and analytical
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10H-Pyrazino[2,3-b][1,4]benzotellurazine, a Novel Tellurium-Containing Heterocyclic System Heteroat. Chem. (IF 0.3) Pub Date : 2020-01-11 Diamond S. Smith, Dallas N. Alexis, Frank R. Fronczek, Thomas Junk
Condensation of 2,3-dichloropyrazine with 2-aminobenzenetellurole and 2-amino-5-methylbenzenetellurole, generated in situ by reduction of the corresponding ditellurides, resulted in the formation of novel 10H-pyrazino[2,3-b][1,4]benzotellurazine and its 7-methyl derivative. The products were purified via their well-crystallized 5,5-dibromo derivatives. X-ray crystallographic analysis of the title compound
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2-Oxiranyl-pyridines: Synthesis and Regioselective Epoxide Ring Openings with Chiral Amines as a Route to Chiral Ligands Heteroat. Chem. (IF 0.3) Pub Date : 2019-10-09 Marzena Wosińska-Hrydczuk, Jacek Skarżewski
New epoxides, derivatives of pyridine, 2,2′-bipyridine, and 1,10-phenanthroline, were synthesized from the respective α-methylazaarenes. The obtained racemic 2-oxiranyl-azaarenes along with styrene oxide and trans-stilbene oxide were submitted to the ring opening with chiral primary amines as a chiral auxiliary. The most effective reaction was run in the presence of Sc(OTf)3/diisopropylethylamine for
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Synthesis of Some New 1,2,4-Triazine and 1,2,5-Oxadiazine Derivatives with Antimicrobial Activity Heteroat. Chem. (IF 0.3) Pub Date : 2019-09-25 Heba E. Hashem, Ahmed M. Abo-Bakr
1,2,4-Triazine and 1,2,5-oxadiazine derivatives 2–12 were obtained from treated 1,3-oxazolone (1) with phenyl hydrazine or hydroxylamine hydrochloride. Chlorotriazine derivative 3 undergoing condensation reactions with different reagents produced new fused tetrazolo-triazine and triazino-quinazolinone derivatives. 1,2,5-Oxadiazine has been used as a synthon for the fused pyrazolo-oxadiazine derivative
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Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes Heteroat. Chem. (IF 0.3) Pub Date : 2019-08-18 Ching-Yuh Chern, Ching-Chun Tseng, Rong-Hong Hsiao, Fung Fuh Wong, Yueh-Hsiung Kuo
This work reports an efficient method for the oxidation reaction of aliphatic, aromatic allylic, and benzylic alcohols into aldehydes catalyzed by the cyclopentadienyl ruthenium(II) complex (RuCpCl(PPh3)2) with bubbled O2. Through further optimizing controlled studies, the tendency order of oxidation reactivity was determined as follows: benzylic alcohols > aromatic allylic alcohols >> aliphatic alcohols
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Theoretical Prediction for Synthetic Realization: Pyramidal Systems ClE[E′4R4] (E = B–Ga, E′ = C–Ge, R = SiMe3, SiMetBu2): A DFT Study Heteroat. Chem. (IF 0.3) Pub Date : 2019-07-22 Olga A. Gapurenko, Vladimir Ya. Lee, Ruslan M. Minyaev, Vladimir I. Minkin
Structure and bonding of hybrid group 13/14 pyramidal molecules ClE[ R4] (E = B–Ga, E′ = C–Ge, R = SiMe3, SiMetBu2) were studied by DFT calculations. Six pyramidal structures are suggested for their potential synthetic realization.
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Synthesis of Benzothiophene-Fused Pyran Derivatives via Piperidine Promoted Domino Reaction Heteroat. Chem. (IF 0.3) Pub Date : 2019-05-02 Shihang Li, Aimin Yu, Jianfa Li, Xiangtai Meng
A new domino reaction between thioaurones and malononitrile has been reported. This reaction allows efficient access to benzothiophene-fused pyran derivatives in good yields under mild reaction conditions. The substrate scope is broad; a series of benzothiophene-fused pyran derivatives have been synthesized.
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Host-Guest Complexations of Amine Boranes and Isoelectronic/Isostructural Quaternary Alkylammonium Cations by Cucurbit[7]uril in Aqueous Solution Heteroat. Chem. (IF 0.3) Pub Date : 2019-04-14 Mona A. Gamal-Eldin, Donal H. Macartney
The host-guest complexation of six amine boranes (R3NBH3) by the macrocyclic host molecule cucurbit uril (CB ) in aqueous solution has been investigated using 1H and 11B NMR spectroscopy. The limiting complexation-induced 1H and 11B chemical shift changes indicate that the amine boranes are included in the hydrophobic cavity of the host molecule. The host-guest stability constants for neutral R3NBH3∙CB
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[4+2] versus [2+2] Homodimerization in P(V) Derivatives of 2,4-Disubstituted Phospholes Heteroat. Chem. (IF 0.3) Pub Date : 2019-04-01 Guillaume Bousrez, Emmanuel Nicolas, Agathe Martinez, Sylviane Chevreux, Florian Jaroschik
Phosphole P(V) derivatives are interesting building blocks for various applications from ligand synthesis to material sciences. We herein describe the preparation and characterisation of new 2,4-disubstituted oxo-, thiooxo-, and selenooxophospholes. The nature of the substituents on the phosphole ring determines the reactivity of these compounds towards homodimerization reactions. Aryl and trimethylsilyl
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Computational Studies of 4-Formylpyridinethiosemicarbazone and Structural and Biological Studies of Its Ni(II) and Cu(II) Complexes Heteroat. Chem. (IF 0.3) Pub Date : 2019-03-03 Mydhili P. Sripathi, Sireesha Berely, Chittireddy Venkata Ramana Reddy
To understand the stability, chelation behaviour, and biological activity of 4-Formylpyridinethiosemicarbazone (H4FPT), it is important to recognize its interactive geometry. Hence, computational studies on geometrically optimized structures of thione and thiol forms of H4FPT were performed. Binary metal complexes of the ligand, H4FPT (L) with the Ni(II) and Cu(II) metal ions (M), were synthesized
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SN-Donor Methylthioanilines and Copper(II) Complexes: Synthesis, Spectral Properties, and In Vitro Antimicrobial Activity Heteroat. Chem. (IF 0.3) Pub Date : 2019-03-03 Temitope E. Olalekan, Adeniyi S. Ogunlaja, Gareth M. Watkins
Methylthioanilines, a series of sulfur-nitrogen donor ligands substituted with OCH3, CH3, Cl, and Br, and their copper(II) complexes have been synthesized and characterized by 1H and 13C NMR, elemental analysis, FTIR, UV-Vis and EPR spectra, molar conductance, and magnetic susceptibility measurements. The NMR spectra of the ligands revealed that the para/ortho protons and para carbon were sensitive
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One-Pot Synthesis of Hypervalent Diaryl(iodo)bismuthanes from o-Carbonyl Iodoarenes by Zincation Heteroat. Chem. (IF 0.3) Pub Date : 2019-02-27 Toshihiro Murafuji, A. F. M. Hafizur Rahman, Daiki Magarifuchi, Masahiro Narita, Isamu Miyakawa, Katsuya Ishiguro, Shin Kamijo
Diaryl(iodo)bismuthanes possessing a hypervalent C=O•••Bi–I bond were conveniently synthesized in a one-pot reaction by using arylzinc reagents generated from o-carbonyl iodobenzenes and zinc powder under ultrasonication. This method is superior to the conventional organolithium and Grignard methods because it has a wide functional group tolerance, requires no protecting group manipulations, and proceeds
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On the Reactivity of N-tert-Butyl-1,2-Diaminoethane: Synthesis of 1-tert-Butyl-2-Imidazoline, Formation of an Intramolecular Carbamate Salt from the Reaction with CO2, and Generation of a Hydroxyalkyl-Substituted Imidazolinium Salt Heteroat. Chem. (IF 0.3) Pub Date : 2019-02-05 Kieren J. Evans, Ben Potrykus, Stephen M. Mansell
N-tert-Butyl-1,2-diaminoethane was shown to react rapidly with atmospheric carbon dioxide to generate the zwitterionic ammonium carbamate salt CO2N(H)C2H4N Bu (1). Reaction of N-tert-butyl-1,2-diaminoethane with triethylorthoformate gave 1-tert-butyl-2-imidazoline (2) in 24% yield after fractional distillation, and the hydroxyalkyl-tethered imidazolinium salt [HOC(Me)2CH2NC2H4N(CH)tBu][Cl] (3) was
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Thiazole Based Carbohydrazide Derivatives as α-Amylase Inhibitor and Their Molecular Docking Study Heteroat. Chem. (IF 0.3) Pub Date : 2019-02-04 Muhammad Taha, Maryam Irshad, Syahrul Imran, Fazal Rahim, Manikandan Selvaraj, Noor Barak Almandil, Ashik Mosaddik, Sridevi Chigurupati, Faisal Nawaz, Nor Hadiani Ismail, Mohamed Ibrahim
In this study we are going to present thiazole based carbohydrazide in search of potent antidiabetic agent as α-amylase inhibitors. Thiazole based carbohydrazide derivatives 1-25 have been synthesized, characterized by 1HNMR, 13CNMR, and EI-MS, and evaluated for α-amylase inhibition. Except compound 11 all analogs showed α-amylase inhibitory activity with IC50 values from 1.709 ± 0.12 to 3.049 ± 0
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Tautomeric Equilibria in Solutions of 2-Phenacylbenzimidazoles Heteroat. Chem. (IF 0.3) Pub Date : 2019-02-03 Agnieszka Skotnicka, Przemysław Czeleń, Ryszard Gawinecki
Detailed NMR spectral analysis of DMSO-d6 solutions of the series of substituted 2-phenacylbenzimidazoles (ketimine form, K) reveals two from three tautomeric forms. Integrals of the 1H NMR signals are used in establishing the molar ratio of tautomers. The experimental analyses are supported by quantum-chemical calculations, which satisfactorily reproduced the experimental trends. Although the reported
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N-Heterocyclic Germylenes: Structural Characterisation of Some Heavy Analogues of the Ubiquitous N-Heterocyclic Carbenes Heteroat. Chem. (IF 0.3) Pub Date : 2019-01-23 Christopher A. Dodds, Alan R. Kennedy, Mark D. Spicer
The X-ray crystal structures of three N-heterocyclic germylenes (NHGes) have been elucidated including the previously unknown 1,3-bis(2,6-dimethylphenyl)diazagermol-2-ylidene (1). In addition, the X-ray crystal structures of the previously synthesised 1,3-bis(2,4,6-trimethylphenyl)diazagermol-2-ylidene (2) and 1,3-bis(2,6-diisopropylphenyl)diazagermol-2-ylidene (3) are also reported. The discrete molecular
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A Thermochemical Parameters and Theoretical Study of the Chlorinated Compounds of Thiophene Heteroat. Chem. (IF 0.3) Pub Date : 2019-01-09 Ibrahim A. M. Saraireh, Mohammednoor Altarawneh, Jibril Alhawarin, Mansour H. Almatarneh
This contribution sets out to compute thermochemical and geometrical parameters of the complete series of chlorinated isomers of thiophene based on the accurate chemistry model of CBS-QB3. Herein, we compute standard entropies, standard enthalpies of formation, standard Gibbs free energies of formation, and heat capacities. Our calculated enthalpy values agree with available limited experimental values
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Imidazole and Azo-Based Schiff Bases Ligands as Highly Active Antifungal and Antioxidant Components Heteroat. Chem. (IF 0.3) Pub Date : 2019-01-03 Siham Slassi, Adeline Fix-Tailler, Gérald Larcher, Amina Amine, Abdelkrim El-Ghayoury
We describe, herein, the synthesis, full characterization, and optical properties of four different ligands L1-L4 which associate an azo group, an imidazole unit, and a Schiff base fragment. The UV-visible absorption bands are characteristic of and transitions with an additional charge transfer between the azobenzene moiety and the imino group. Finally the determination of MIC80 values against pathogenic
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Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1,4-Naphtho- and Benzoquinone Derivatives Containing N-, S-, O-Substituted Heteroat. Chem. (IF 0.3) Pub Date : 2019-01-02 Semih Kurban, Nahide Gulsah Deniz, Cigdem Sayil, Mustafa Ozyurek, Kubilay Guclu, Maryna Stasevych, Viktor Zvarych, Olena Komarovska-Porokhnyavet, Volodymyr Novikov
A series of new 1,4-naphtho- and benzoquinone derivatives possessing N-, S-, O-substituted groups which has not been reported yet has been synthesized from 2,3-dichloro-1,4-naphthoquinone 1 and 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione 15 involving a Michael addition. In the synthesized compounds, antimicrobial activity at low concentrations against Escherichia coli B-906, Staphylococcus aureus
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An Efficient Selectfluor-Mediated Oxidative Thio- and Selenocyanation of Diversely Substituted Indoles and Carbazoles Heteroat. Chem. (IF 0.3) Pub Date : 2019-01-02 Rodrigo Abonia, Luisa F. Gutierrez, Angela T. Zwarycz, Sebastián Correa Smits, Kenneth K. Laali
A facile Selectfluor-mediated oxidative method for direct introduction of SCN and SeCN groups into diversely substituted indoles and carbazoles is described, by employing readily available thiocyanate and selenocyanate salts, and the scope of the method is underscored by providing 24 examples. The feasibility to sequentially introduce SCN followed by SeCN on a carbazole framework and to synthesize
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Regio‐ and stereoselective addition of trans ‐Pt(TeAr)(SiMe 3 )( PE t 3 ) 2 to terminal alkynes leading to cis ‐[( Z )‐ β ‐trimethylsilylalkenyl]platinum( II ) complexes Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-15 Li‐Biao Han,Farzad Mirzaei,Shigeru Shimada
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Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na 2 B 12 H 11 S) Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-13 Masahiro Yamagami,Tomoyuki Tajima,Kango Ishimoto,Hideaki Miyake,Hiroyuki Michiue,Yutaka Takaguchi
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A new method to prepare functional phosphines through steady‐state photolysis of triarylphosphines Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-13 Shinro Yasui,Taro Ando,Masashi Ozaki,Yuya Ogawa,Kosei Shioji
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From catechol‐tocopherol to catechol‐hydroquinone polyphenolic antioxidant hybrids Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-10 Caterina Viglianisi,Stefano Menichetti,Paola Morelli,Andrea Baschieri,Riccardo Amorati
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A “masked” source for the phosphaalkene MesP=CH2 : Trapping, rearrangement, and oligomerization Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Leixing Chen,Shuai Wang,Patrick Werz,Zeyu Han,Derek P. Gates
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Synthesis of novel fluorous pyridinium ionic liquids Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Mitsunori Honda,Kohei Ashizawa,Ko-Ki Kunimoto,Masahito Segi
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Nitroselenation of carbon-carbon triple bond by PhSeSePh and NO/O2or NO2 Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Yutaka Nishiyama,Mari Sumida,Noboru Sonoda
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Heteroatom effects toward isomerization of intermediates in Wittig reactions of non-stabilized phosphonium ylides bearing a phosphaheteratriptycene skeleton with benzaldehyde Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Yosuke Uchiyama,Suguru Kuniya,Ryo Watanabe,Takemaru Ohtsuki
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Preparation and reactivity of benzo-1,2-dichalcogenete derivatives and their bis(triphenylphosphine)platinum complexes Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Takeshi Kimura,Tsukasa Nakahodo,Hisashi Fujihara
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Photoreactions of Sc3 N@I h -C80 and Lu3 N@I h -C80 with disilirane: Isolation and characterization of labile 1,2-adducts Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Masahiro Kako,Fumiaki Ozeki,Shinji Kanzawa,Shinpei Fukazawa,Kumiko Sato,Michio Yamada,Yutaka Maeda,Makoto Furukawa,Takeshi Akasaka
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Synthesis of optically active tertiary phosphine oxides: A historical overview and the latest advances Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Jacek Chrzanowski,Dorota Krasowska,Jozef Drabowicz
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Behavior of I4 σ(4c-6e) in tellurolane system and related species, elucidated by QTAIM dual functional analysis with QC calculations Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Satoko Hayashi,Taro Nishide,Waro Nakanishi
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Dibromometallyl-iron complexes generated by the recombination of an alumanyl-iron complex with EBr3 (E = Al, Ga) Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Tatsuya Yanagisawa,Yoshiyuki Mizuhata,Norihiro Tokitoh
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Comparison of homofugality among alkyl groups attached to tin atom Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Akio Kamimura,Tatsuro Yoshinaga,Koichiro Miyazaki,Takuji Kawamoto
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Alkoxy(tetraaryl)silicates bearing 9,10-disilatriptycene skeleton Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Shintaro Ishida,Minori Takiguchi,Takeaki Iwamoto
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Uniquely folded shapes, photophysical properties, and recognition abilities of macrocyclic BODIPY oligomers Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Tomohiro Hojo,Takashi Nakamura,Ryota Matsuoka,Tatsuya Nabeshima
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Reaction of arylhydrazines with diaryl ditellurides in the air: Insight into bimolecular homolytic substitution on tellurium via Aryl-Te bond cleavage Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Yuki Yamamoto,Fumiya Sato,Shintaro Kodama,Akihiro Nomoto,Akiya Ogawa
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Synthesis and structure of bis(ethylenedioxy)-1,4,5,8-tetraselenanaphthalene Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Ryoji Watanabe,Masashi Hasegawa,Masahiko Iyoda
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Synthesis, structures, and reactivity of 9,9-dialkoxy-9-silafluorenes Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Ken-ichiro Kanno,Satoshi Hirose,Soichiro Kyushin
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Studies on diverse chemical species derived from chalcogen atoms ~ The Footprint of Professor Naomichi Furukawa in Heteroatom Chemistry ~ Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Soichi Sato
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Oxidative addition of (RO)2P(O)H to Pt(0) complexes generating Pt-H complexes: P(O)-H bond cleavage vs P(O-H) bond cleavage Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Tieqiao Chen,Li-Biao Han
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Dehydrogenative Sn-E (E = S, Se) bond formation catalyzed by an iron complex Heteroat. Chem. (IF 0.3) Pub Date : 2018-12-01 Masumi Itazaki, Yudai Ogawa, Wataru Nakamura, Hiroshi Nakazawa
Iron complex-catalyzed dehydrogenative Sn‒E (E = S, Se) bond formation of hydrostannane with thiol and selenol was achieved. All new compounds were fully characterized using H, C{H}, Se{H}, and Sn{H} NMR measurements and elemental analyses. The structure of 1,1'-(1,3-dithia-2,2-dibutylstanyl)-[3]ferrocenophane was confirmed by single crystal
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Self-assembly of sulfur-containing heterocyclic compounds constructed by thianthrene units and their sulfonium salts Heteroat. Chem. (IF 0.3) Pub Date : 2018-11-29 Kazunori Hirabayashi,Kenki Ebine,Youhei Kawabata,Yoshihiro Yoshida,Toshio Shimizu
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Synthesis and properties of redox-switchable zinc complexes of 10,15,20-triaryl-15-aza-5-oxaporphyrin Heteroat. Chem. (IF 0.3) Pub Date : 2018-11-26 Keisuke Sudoh, Ko Furukawa, Haruyuki Nakano, Soji Shimizu, Yoshihiro Matano
A tribute to Professor Naomichi Furukawa on the Occasion of his 82nd birthday By Invitation only Contract grant sponsor: JSPS KAKENHI Contract grant number: 18H01961 Contract grant number: 15K05392 Contract grant number: 18K05036 1Department of Fundamental Sciences, Graduate School of Science and Technology, Niigata University, Niigata, Japan 2Center for Coordination of Research Facilities, Institute
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π-Dimerization ability of conjugated oligomer dication diradicaloids composed of dithienylpyrrole and benzodithiophene units Heteroat. Chem. (IF 0.3) Pub Date : 2018-11-20 Takahiro Akahane,Masayoshi Takase,Yasuhiro Mazaki,Tohru Nishinaga