The current study aims to evaluate the ameliorative effect of polydatin-loaded-chitosan nanoparticles (PD-CSNPs), polydatin (PD), and metformin on Diabetes-induced pulmonary disorders. After induction of diabetes, rats are classified into five groups, diabetic control and diabetic rats treated daily for four weeks with; PD, PD-CSNPs, chitosan-nanoparticles and metformin. Rats treated with PD and PD-CSNPs

In this paper, we investigate a (discretization) Caputo fractional glucose-insulin model qualitatively with incommensurate orders that appear in Bergman's minimal model. After intravenous tolerance testing, the model is used to characterize the blood insulin and glucose metabolism. We also prove that the presented model possesses existence, uniqueness, non-negative, and boundedness solution. We also

In this paper, adsorption of Congo red (CR) onto L-cysteine decorated with reduced graphene oxide/polyaniline composite at room temperature was investigated. The morphology and structure properties of as-prepared nanocomposite were verified by UV–visible spectroscopy (UV–visible), powder X-ray diffraction (XRD), Fourier transform infrared spectrophotometry (FTIR), scanning electron microscopy (SEM)

In this research article, a new idea concerning the application of concept of the continued fractions to the expansion of the geopotential is treated. The perturbed motion of the satellite in the oblate gravitational field of the Earth using a potential of a continued fractions procedure is studied. To compare with the usual perturbation theory, the continued fraction series is truncated beyond the

ABSTRACT Silver-coated ZrO2 and individual ZrO2 nanoparticles have been synthesized using the simple reduction and co-precipitation methods, respectively. The synthesized products were examined using the X-ray diffraction, energy-dispersive X-ray and UV–visible spectroscopy, which confirmed the successful synthesis of materials. Scanning electron microscopy and transmission electron microscopy revealed

Despite the significant influence of the microbial communities that inhabit the ruminant’s gastrointestinal tract on their health and production, the study of the composition and variations in sheep and goats gut microbiome is limited. The present study investigated the faecal microbiomes of sheep and goats at 6 and 12 months of age using Illumina MiSeq, targeting the 16S rRNA gene V3-V4 region sequences

ABSTRACT The K n  -  residual graph was proposed by P. Erdös, F. Harary and M. Klaw. They also proposed conclusions and conjectures regarding connected m − K n  -  residual graphs. When m = 1 , n ≠ 1 , 2 , 3 , 4 , the authors proved that K n + 1 × K 2 is the only connected residual graph with a minimum order. In this paper, we proved that there are three different connected 3 − K 5  -  residual graphs

ABSTRACT This study evaluated the anti-diabetic and hepatic protective effect of the aqueous extract of the Aloe perryi (AP) in streptozotocin-induced diabetic rats. Rat were divided into control, diabetic, diabetic + glimepiride, diabetic + AP (150 or 300 mg/Kg) groups. AP (300 mg/Kg) alone lowered fasting serum glucose levels but increased insulin levels and HOMA-β. At both doses, AP significantly

In this study, versatile multifunctional Schiff base (SB) derivatives were synthesized. Compounds 1–8 were prepared by a mild condition and were pharmacologically assessed for their role in vitro anti-cancer and their impact on human fibrosarcoma (HT-1080) and cervical cancer cells (HeLa), in addition to their antimicrobial activity regarding fungal strains, gram-positive and gram-negative bacteria

ABSTRACT Amprolium is one of the veterinary pharmaceuticals that has been widely used as antibacterial agents and as a growth promoter in livestock, it can produce chronic adverse actions that could affect many organisms and humans. In this study, Salvadora persica stem ash and roots were used as biosorbent for the removal of Amprolium hydrochloride (AMP) from aqueous systems. The effect of different

ABSTRACT Favipiravir is a broad spectrum antiviral drug that has shown activity against many viruses. Sequel to the recent outbreak of COVID-19, favipiravir is investigated as one of the potential drugs for the treatment of SARS-CoV-2. To augment these efforts, this article reports the rotational isomers, tautomeric states, electronic and spectral properties of favipiravir and its five analogues (Cl

ABSTRACT The COVID-19 pandemic caused by SARS-CoV-2 has started in December 2019 in Wuhan, China, and become a global health problem. The SARS-COV-2 main protease (Mpro) play a crucial role in the multiplication and control of virus activity. Therefore, we assume that the inhibition of these enzymes inhibits viral replication. To determine potential inhibitors of this protease among existing chemical

Spinach is a highly nutritive and medicinally important leafy vegetable cultivated in many countries worldwide. Diversity in the gene pool of a species may affect the adaptability to a new environment as well as to develop new varieties more tolerant to stress and pathogens. To assess the genetic variability of species, morphological traits are considered as the simplest markers. Therefore, a field

Bacterial drug resistance poses a global challenge to established antibacterial prevention and treatment schemes. Recent approaches focus on raising algal extracts' efficacy by fusing them to other antibacterial agents employing nanotechnology. Here, we successfully biosynthesized AgNPs using Galaxaura rugosa crude methanol extract (AgNPCR) and raw powder aqueous (AgNPAQ) solution. The resultant AgNPs

The current study aimed to investigate the antioxidant, anti-inflammatory and hepatoprotective activity of olive fruit pulp extract (OFPE) through in vivo- and in vitro-based studies. Oral administration of OFPE demonstrated a significant reduction in liver biomarker enzymes, inflammatory marker (IL-6, TNF-α, and C-reactive protein (CRP)) level and recovered the antioxidant enzymes and total antioxidant

The Kingdom of Saudi Arabia (KSA) is one of the rising countries in the Gulf region but always scared of water; being present in the arid desert. Among some water resources groundwater is one of the most significant ones in this country but unfortunately is being contaminated by the toxic metal ions. The present article describes the status of groundwater contamination by toxic metal ions. The meal

ABSTRACT A proficient, eco-friendly, and cost-effective catalyst for remediation of organic contaminants in the environment is a burning issue in recent decades. In the present study, the cobalt doped MnO (Co-MnO) photocatalyst was synthesized via cost-effective and environmentally friendly reverse micelle route. The X-ray diffraction (XRD) results confirmed the synthesis of well-defined cubic-phased

ABSTRACT COVID-19 pandemic has poses urgent health challenge, and this project aims to identify potential inhibitors to combat this virus. We screened 198 bioactive compounds from five selected medicinal plants previously reported to be antiviral against SARS-CoV-2 protease and two co-receptors followed by molecular dynamics simulations. From the screened compounds, Astragalin demonstrated very strong

A theoretical assessment of the effects of the OH, NH2 and Br substituents on the properties of 2,2′-bipyridine has been carried out using density functional theory approach. The substituents were found to alter both electronic and structural properties of substituted 2,2′-bipyridine with the inductive and resonance effects playing significant roles. For the relative stability study, an order of ortho

Apart from being a vital and exciting field in mathematics with interesting results, projective spaces have various applications in design theory, coding theory, physics, combinatorics, number theory and extremal combinatorial problems. In this paper, we consider real, complex and quaternion projective spaces. We focus on the geometric feature of the sectional curvatures. We first study the real and

In this paper, using q − derivative operator, we define the class Σ q , v ∗ ( n , α , β , λ ) of meromorphic univalent functions and obtain coefficient estimates, distortion, closure theorems, modified Hadamard products, some radii for functions in this class and family of integral operators. Further, we determine partial sums results.

This work employs two new modified computational schemes to find the exact travelling and solitary wave solutions of the general modified Degasperis-Procesi Camassa-Holm (DP CH) equation that is used to illustrate the dynamical behaviour of shallow water. These schemes are the modified exponential expansion and the modified Khater methods that are used to formulate the computational solutions in various

In this work, the totally 31 Vertical Electric Soundings (VESes) were carried out at wadi El Madamud, Southeastern Luxor city. These are processed and interpreted the forms of geologic models composed of five geoelectric layers of varying resistivities, lithologies, depths and thicknesses. They are surfacial unconsolidated dry silts, sands and gravels, consolidated silts, sandy gravels, sandstone and

Olanzapine (OLZ), one of the second-generation antipsychotics, is effective in stress accompanying with chronic psychiatric disease. But the effect of chronic long-standing use of OLZ administration on the liver and its association with metabolic side effects plus weight gain is still unclear. The objective of our study was to evaluate the antioxidant effect of Hypericum perforatum (HP) on OLZ-induced

Culex pipiens (Diptera: Culicidae) is one of the most prevalent mosquitoes particularly in the Al-Madinah Al-Munawwarah region, Kingdom of Saudi Arabia, transmitting numerous diseases such as arboviruses, avian malaria, elephantiasis, dirofilariasis, and encephalitis. Worldwide, Culex pipiens has developed resistance to numerous insecticides; therefore, considerable efforts have been done to introduce

ABSTRACT Firstly, original poly(vinyl alcohol-co-ethylene) (PVA-co-PE)/cellulose composite membranes were prepared and characterized. Then these composite membranes were applied for wastewater treatment. For this purpose, separation of Iron (III) and Copper (II) ions from the aqueous solutions with stirred ultrafiltration cell was investigated. These metal ions were complexed by using alginic acid

ABSTRACT Astragalus spinous is a native perennial shrubs from Leguminosae family that widely distributed in severely degraded lands at northern Kuwait. A restoration program was applied via levelling and refilling the quarries and rehabilitation of the natural vegetation and wildlife to their original outward appearance before degradation. The existence of Astragalus shrubs indicated that soil after

The theory of differential inclusions has played a central role in many areas as biological systems, physical problems and population dynamics. The principle aim of our work is to compute explicitly the discrete approximate solution of a differential inclusion including a maximal monotone operator. Also we present a numerical application of our results for showing how to compute the discrete approximate

ABSTRACT An ecofriendly and efficient preparation of a set of a new 1-propylimidazolium-based ionic liquids (1–20) has been manufactured by using both microwave irradiation and conventional procedure. Different spectral analysis (FT-IR, mass spectra, NMR and elemental analysis) were utilized to examine the structures of the newly prepared ILs. The in vitro antitumor activities of all ILs (1–20) were

The present study was planned to explore the relationship between soil chemistry with bacterial population of Bt and non-Bt cotton and their phenotypic and molecular characteristics. The pre-plant soil and rhizospheres of Bt and non-Bt cotton were collected and analyzed for some soil parameters and bacterial population. The bacterial isolates were analyzed for their morphological, biochemical, and

This paper points out several exact travelling wave solutions for ( 1 + 1 ) -dimensional Ito integro-differential equation via the Riccati–Bernoulli sub-ODE approach. We also aim to develop a numerical solution of the respective equation using central finite difference formulas. The stability of the presented exact and numerical solutions is also deduced using the Hamiltonian system and Von Neumann's

In this work, we have suggested a neat method of obtaining the fractional diffusion equation for an anomalous anisotropic diffusion process using fractal brush structure as a background medium. For the sake of completeness, we intend to present an analytical solution in the case of the Dirichlet boundary condition. Finally, some notes and remarks are represented to show the vital role of a physical

The integration of remotely sensed data allowed the successful characterization of the hydrothermal alteration zones of the Abu–Gaharish area in the Central Eastern Desert of Egypt using image transformation techniques. The integration of several evidential maps highlighted the plausible areas with high concentrations of argillic and phyllic, key hydrothermal minerals that reflect the intensity of

ABSTRACT The Sebkha of Oran, given its large size, is considered to be a remarkable feature of the west Algeria. The study of its evolution proved to be essential, following many interrogations specifically concerning its extension and its role in the ecological balance of the region. We aim to study the changes of the Sebkha over the last 20 years. To conduct the study, we used the Synthetic Aperture

The purpose of this study was to develop a self-nanoemulsifying drug delivery system (SNEDDS) for the improvement of solubility and bioavailability of luteolin in order to enhance its therapeutic benefits. Formulations were prepared by spontaneous emulsification method which involved low energy mixing of appropriate amounts ofcastor oil, kolliphor & polyethylene glycol 200. The developed formulae were

In this report, the electric field strength impact on MHD Carreau AA7075 – water nanofluid flows is controlled by a stretching sheet with formable thickness. The three simple models of nanoparticle shapes are enrolled into a pattern, i.e. sphere ( m = 3.0 ) , cylinder ( m = 6.3698 ) and lamina ( m = 16.1576 ) . The powerful partial differential equations (PDEs) are reconstructed into ordinary differential

This study aimed to evaluate the relationship between tumour-necrosis factor-alpha (TNF-α), interleukin (IL)-18, IL-23, IL-35 and Heilcobacter (H) pylori infection with T2DM. A total of 25 healthy subjects and 102 confirmed T2DM patients were enrolled in this study. Diabetic patients were subdivided into six groups according to antidiabetic therapy. Diabetic non-treated patients exhibited a significant

The propagation of some new electrostatic cnoidal, super-solitons, super-periodic and shocklike waves in Earth magneto-tail electron acoustic (EA) plasma at critical density has been investigated via MKP equation. These MKP solutions are obtained by the method of expansion Jacobian elliptic function (EMJEF). Numerous of the given solutions are significant on the observations of broadband electrostatic

This study investigates the photo-thermo-elastic interaction in an infinite semi-conductor material with cylindrical cavities. The effect of variable thermal conductivity through the photo-thermo-elastic transport process is studied using the coupled models of thermo-elasticity and plasma waves. The internal surface of the cylindrical cavity is loaded by a thermal shock varying heat. The eigenvalue

Obtaining the equations of motion for an element in finite element analysis (FEA) model in the analysis of a multi-body system (MBS) having component elastic elements represents an important (maybe the main) step to build a soft able to solve such a problem numerically. In use FEA in the study of a MBS with elastic elements, the method of Lagrange's equations is especially used at present. This method

One of the synthetic pyrethroid pesticides is Cypermethrin (CYP) which has been widely used in Egypt. CYP is primarily believed to be safe for ordinary application. Many studies presented its neural and reproductive toxicity in nonmammalian, mammalian and different animal species. Up till now, there is not enough information known about the reproductive toxicity mechanism induced by the CYP and there

The water demand in Egypt has risen due to limited surface water and varied uses. Geological and hydrological data, radar, optical remote sensing data, and Geographic Information System techniques delineate groundwater availability zones in the study area. Thematic layers (lithology, topography, slope, stream networks, lineaments, and rainfall) were integrated into the ArcGIS 10.4 using a linear weighted

Considering the increasing incidence of fatal aluminium phosphide (ALP) poisoning and its toxicological aspects and also the paucity of our knowledge concerning the ALP effect on adipose tissue and adipokines, the present study aimed to assess the effect of acute and sub-chronic ALP inhalation exposure on adipose tissue characteristics and histological alterations in rats. This experimental study was

Carbonyl reductase 1 (CBR1), a short-chain dehydrogenase/reductase, is important in the phase I reduction of drugs. Glutathione (GSH) facilitates the access of low-affinity substrates to the CBR1 active site. This study investigates the path of substrates to the CBR1 active site when GSH occludes the entrance to NADP and binds its catalytic residues. A set of CBR1 structures bound with GSH were subjected

This study investigated the susceptibility of eight different animal species (rat, mice, guinea pigs, hamsters, rabbits, sheep, goats, and chicken) experimentally infected with Trypanosoma evansi isolated from camels. In all laboratory animals, the number of trypanosomes was standardized according to the weight of the animal, and daily examination of the blood was conducted to assess the presence of

High-quality nanostructure of dysprosium substituted nickel–cobalt ferrite and their composite with reduced graphene oxide (rGO) were synthesized. The structuraland photocatalytic properties of prepared samples were studied. The XRD and FTIR analysis confirmed the FCC spinel structure. The calculated average crystallite size of nanoparticles was around 7.8 nm. The bandgap energy of synthesized composition

The present calculations show that the application of an external magnetic field can generate additional component of the wakefield suitable for Terahertz (THz) radiation generation in a collisional plasma. Based on the approach of perturbation technique under quasi-static approximation, a study is made on the field of emitted radiation pulses from the wakefield when the super-Gaussian laser beams

The properties of chemical compounds are very important for the studies of the non-isomorphism phenomenon's related to the molecular graphs. Topological indices (TIs) are one of the mathematical tools which are used to study these properties. Gutman and Trinajsti [Graph theory and molecular orbitals. Total π-electron energy of alternant hydrocarbons. Chem Phys Lett. 1972;17(4):535–538] defined the

The quest for improved visible light absorption in ZnO-based photocatalysts and photodetectors is a prevailing research problem. One method of solving this problem is by narrowing the band gap of this material well into the range of visible light energy. In this work, we have demonstrated considerable band narrowing into the visible region in our electrospun ternary ZnO–Zn2SnO4 nanofibres. We also

Our aim in this article is to present a collocation method to solve two population models for single and interacting species. For this, logistic growth model and prey–predator model are examined. These models are solved numerically by Pell–Lucas collocation method. The method gives the approximate solutions of these models in form of truncated Pell–Lucas series. By utilizing Pell–Lucas collocation

Weaning is known to be the most stressful and critical transition experienced by lambs, it affects the structure of the gastrointestinal tract microbiomes, which significantly influences the lamb’s health and performance. The present study identified the structure of lambs' pre- and post-weaning fecal microbiomes to define the implications of the weaning transition. Illumina MiSeq yielded a total of 5169 sequence

Electromagnetic wave is a viable means of introducing energy into reservoirs for the recovery of residual oil. However, previous studies have not considered the precise frequency of the electromagnetic (EM) wave. These studies focused on EM heating, not considering the efficiency dependence of EM transmitter and EM propagation on the EM properties of the medium. Thus, sandstone effective permittivity

Here in our paper, we present two new subclasses of multivalent analytic functions and complex order by using q–p-valent Cătaş operator. Also we obtain coefficient estimates and consequent inclusion relationships involving the N i , δ p , q ( f ) -neighbourhood of these classes.

C-phycocyanin (C-PC) is a protein–pigment widely used in nutrition and pharmaceutical applications. High purity of C-PC is a limiting factor required for its medical use; hence purity improvement with successful plausible pharmaceutical application is the state of the art of the present work. Highly purified C-PC (A620/A280 = 6.6) was obtained from Thermosynechococcus elongatus. Combined enzymatic

This article deals with the development of the number of periodic solutions for ordinary differential equations. We investigated focal values for first-order non-autonomous differential equation for periodic solutions from a fine focus z = 0 . Periodic solutions with polynomial coefficients are executed for classes C 10 , 3 , C 10 , 4 , and C 10 , 5 . Limit cycles are found for both non-homogeneous

ABSTRACT This study investigated the effect of using calcium carbonate (CaCO3) nanoparticles on the microstructural properties, flexural strength and fracture toughness of ceramic nanomaterials. The flexural strength and fracture toughness were evaluated for CaCO3 nanoparticle contents of 1%, 2%, and 3% by weight of cement powder. The microstructural analyses from X-ray diffraction showed that nano-CaCO3

The nonlinear propagation of ion-acoustic Gardner solitons (GSs) and double layers (DLs) in electron-positron-ion (EPI) plasma in the presence of an external static magnetic field has been examined. The Korteweg–de Vries (KdV), modified KdV (mKdV), and Gardner equations have been derived by the reductive perturbation technique. It is seen that the amplitude, polarity, speed, width of such solitons

Based on commercial bentonite (bento) and two metal precursors, including NiCl2 and CoCl2, diverse series of composites were prepared by incipient wet impregnation. The prepared composites were characterized by X-ray diffraction, scanning electron microscopy and energy-dispersive X-Ray spectroscopy. X-ray diffraction studies show that the crystallite size decreased as increasing the wt. % of cobalt

ABSTRACT Mazucheli et al. introduced a new transformed model referred as the unit-Weibull (UW) distribution with uni- and anti-unimodal, decreasing and increasing shaped density along with bathtub shaped, constant and non-decreasing hazard rates. Here we consider inference upon stress and strength reliability using different statistical procedures. Under the framework that stress–strength components

In recent decades, many families of distributions and, consequently, new distributions are proposed in order to provide a good flexibility and fit to real data sets. However, several of these distributions have a complicated shape to express their probability density function (pdf) and cumulative distribution function (cdf). Examples of families that involve such functions are: beta-G (see Eugene et