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The quantum mechanics of skincare: A context for the biochemistry curriculum Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-03-08 Peter A. C. McPherson, Lynsey Alphonso, Ben M. Johnston
Designing a relevant and engaging curriculum for biochemistry undergraduates can be challenging for topics which are at the periphery of the subject. We have used the framework of context‐based learning as a means of assessing understanding of quantum theory in a group of students in their junior year. Our context, the role of retinol in skincare, provides a basis for the simple application of quantum
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Development of an integrated and project‐based laboratory course in upper‐level biochemistry and molecular biology Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-28 Yange Liu, Shuo Tu, Xiaojuan Hu, Xiangyang Xiong, Zezheng Pan, Zhuoqi Liu, Weifeng Zhu, Daya Luo, Xiangpei Cui, Chunhong Huang, Caifeng Xie
An integrated and projected‐based laboratory course was described, integrating interconnected knowledge points and biochemistry and molecular biology techniques on a research project‐based system. The program, which served as an essential extension of theoretical courses to practice, was conducted with a sophomore of basic medical science who had completed the course in medical biochemistry and molecular
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Use of OneNote class notebook as a combined electronic laboratory notebook and content delivery tool in an introductory biochemistry laboratory course Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-27 Ahlia Khan‐Trottier
The COVID‐19 pandemic has forced a shift in thinking regarding the safe delivery of wet laboratory courses. While we were fortunate to have the capacity to continue delivering wet laboratory experiments with physical distancing and other measures in place, modifications to the mechanisms of delivery within courses were necessary to minimize risk to students and teaching staff. One such modification
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If you are learner‐centered and you know it, raise your hand: Perspectives on and implementation of pedagogical changes by science instructors during the COVID‐19 pandemic Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-27 Cristine Donham, Hanbo Hong, Adriana Signorini, Erik Menke, Petra Kranzfelder
Students at Minority‐Serving Institutions (MSIs) faced significant hardships while trying to learn through emergency remote teaching (ERT) during the COVID‐19 pandemic. Our research aims to investigate if science, technology, engineering, and mathematics (STEM) instructors thought about and enacted more learner‐centered teaching practices to alleviate some of this stress encountered by their students
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An idea to explore: Cultivating the art of proposal writing among graduate students Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-27 Rajiv K. Kar
Proposal writing is an essential requirement for making progress in academics. Learning this skill necessitates support from a mentor to cultivate effective habits. It entails effective strategies from graduate students, such as literature reading and using online tools. Additionally, they must develop an understanding of resource accountability, system thinking, and considering deadlines as a driving
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Detection and enzymatic characterization of human saliva amylase Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-24 Chiara Theresa Vey, Viola Kaygusuz, Josefa Sophia Kayser, Andreas Beyer
As a rule, an experiment carried out at school or in undergraduate study courses is rather simple and not very informative. However, when the experiments are to be performed using modern methods, they are often abstract and difficult to understand. Here, we describe a quick and simple experiment, namely the enzymatic characterization of ptyalin (human salivary amylase) using a starch degradation assay
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Enzyme Kinetics Analysis: An online tool for analyzing enzyme initial rate data and teaching enzyme kinetics Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-24 Daniel A. Mak, Sebastian Dunn, David Coombes, Carlo R. Carere, Jane R. Allison, Volker Nock, André O. Hudson, Renwick C. J. Dobson
Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and cellular biology to pharmacology. However, because enzyme
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An early-curricular team learning activity to foster integration of biochemical concepts and clinical sciences in undergraduate medical education Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-15 Martin Schmidt, Brian Pinney, Craig Canby, April Vargus, Marianka Pille
The ability to connect key concepts of biochemistry with clinical presentations is essential for the development of clinical reasoning skills and adaptive expertise in medical trainees. To support the integration of foundational and clinical sciences in our undergraduate health science curricula, we developed a small group active learning exercise during which interprofessional groups of students use
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Methods of biotechnology Biotech BioBrawl: A competition-based learning approach to biotechnology Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-13 Nicholas Skiados, Rabeea Summer Rehman, Megan Riley, Kersten T. Schroeder
Biotechnology students entering the workforce often struggle in their application of textbook knowledge to build the solutions that we see in science and health fields today. Some students may be naive to what a job in the biotechnology industry can encompass. Students should graduate having a firm grasp of the prospects of their field and have the confidence to begin contributing to the growth of
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An idea to explore: Introduction of “biochemical tales” in medical education—Learning made fun Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-06 Krishna Mohan Surapaneni
Innovations in medical education, including the integration of narrative-based tales, are transforming the way complex biochemical concepts are taught and understood. In this “Idea to Explore”, the essence of integrating tales that personify molecules and depict biochemical processes as engaging stories to enhance student engagement, promote active learning, and improve knowledge retention is discussed
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Assessment of the effectiveness of an introductory general chemistry course in dentistry students enrolled in a biochemistry course Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-03 Gloria Gutiérrez-Venegas, Marisol Rosas-Martínez, Itzel Juárez-Ramos, Jesús Iván Jiménez-Rivera
As a strategy to carry out a better achievement in the Biochemistry course, undergraduate dentistry education manage a traditional course on the basic concepts of general chemistry necessary in the understanding of Biochemistry. In order to evaluate the effectiveness of learning outcome, we aimed to develop an evaluation tool that was applied to first-year dental students before and after receiving
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The implementation of an active inquiry learning centered “7E” teaching mode in the cell biology course enhances the learning effects of postgraduate students Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-03 Jingjing Han, Lina Zhang, Liucai Yang, Yougen Luo, Ruiqin Yao, Xuebin Qu
The primary objective of science postgraduate education is to foster students' capacity for creative thinking and problem-solving, particularly in the context of scientific research quality. In order to achieve this goal, the “7E” teaching mood has been implemented in the cell biology course for postgraduate students to promote student-centered active inquiry learning instead of breaking away from
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An interdisciplinary course on computer-aided drug discovery to broaden student participation in original scientific research Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-02-03 Christopher Stratton, Avery Christensen, Chelsey Jordan, Brian A. Salvatore, Elahe Mahdavian
We present a new highly interdisciplinary course in computer-aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational
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Blended learning in biochemistry: The development of pre-class and post-class learning aids for electron transport chain and oxidative phosphorylation Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-16 Rebecca K. Y. Lee, Bernard Y. N. Ng, Daisy M. H. Chen
Electron transport chain and oxidative phosphorylation are always a challenging topic for students studying metabolism. We had adopted blended learning in metabolism teaching and evaluated the learning experiences of students. In this project, a pre-class learning aid the Story Mode and a post-class learning aid the Revision Mode in the Powerland was developed that facilitated students learning electron
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Multi-focused laboratory experiments based on Quorum Sensing and Quorum Quenching for acquiring Microbial Physiology concepts Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-13 Mariela Analía Torres, Alejandra Leonor Valdez, Carolina de Lourdes Olea, María Fernanda Figueroa, Carlos Gabriel Nieto-Peñalver
After a time away from the classrooms and laboratories due to the global pandemic, the return to teaching activities during the semester represented a challenge to both teachers and students. Our particular situation in a Microbial Physiology course was the necessity of imparting in shorter time, laboratory practices that usually take longer. This article describes a 2-week-long laboratory exercise
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Assessment of early scientific research skills training for medical undergraduates in China Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-13 Xueer Liu, Huiyu Chen, Xiaoying Liu, Teng Teng, Xuemei Li, Dan Zhu, Xinyu Zhou
The medical field is facing a physician-scientist shortage, threatening future medical research and development. Medical institutions can contribute to developing physician-scientists by stimulating students' involvement in research. In this study, a medical undergraduate teaching module to develop research skills and encourage interest in research was held in Chongqing, China. Undergraduate medical
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Teaching biologics design using molecular modeling and simulations Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-10 Andrew Phillips, Anusha Srinivas, Ilina Prentoska, Margaret O'Dea, Matthew Kustrup, Sarah Hurley, Savannah Bruno, Vy Nguyen, Pin-Kuang Lai
Teaching chemistry and biology students about biologics design remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing proper formulations to stabilize mAbs, such as preventing
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Writing a literature review as a class project in an upper-level undergraduate biochemistry course Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-09 Sanchita Hati, Sudeep Bhattacharyya
A literature review is an important part of conducting academic research. Knowing how to conduct a literature search and write a high-quality literature review is a valuable skill. Herein, the authors describe the method of introducing a literature review writing exercise in an upper-level biochemistry course. Since 2020, authors have collaborated with numerous undergraduates writing literature reviews
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A comprehensive stem cell laboratory module with blended learning for medical students at Tongji University Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2024-01-08 Jie Xu, Zhihua Shao, Song Jia, Jihong Sha, Jiao Li, Furong Gao, Xiujuan Shi, Juan Wang, Caixia Jin, Mei Jiang, Haibin Tian, Jinfeng Cao, Hu Pu, Lei Xu, Lixia Lu
The laboratory practice “Primary culture and directional differentiation of rat bone marrow mesenchymal stem cells (BMSCs)” is part of a required course for sophomore medical students at Tongji university, which has been conducted since 2012. Blended learning has been widely applied in medical courses. Based on a student-centered teaching philosophy, we reconstructed a comprehensive stem cell laboratory
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Evaluating ChatGPT as a self-learning tool in medical biochemistry: A performance assessment in undergraduate medical university examination Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-12-19 Krishna Mohan Surapaneni, Anusha Rajajagadeesan, Lakshmi Goudhaman, Shalini Lakshmanan, Saranya Sundaramoorthi, Dineshkumar Ravi, Kalaiselvi Rajendiran, Porchelvan Swaminathan
The emergence of ChatGPT as one of the most advanced chatbots and its ability to generate diverse data has given room for numerous discussions worldwide regarding its utility, particularly in advancing medical education and research. This study seeks to assess the performance of ChatGPT in medical biochemistry to evaluate its potential as an effective self-learning tool for medical students. This evaluation
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Students’ perceptions of online education: A session at the FAOBMB–IUBMB–CBSL virtual education symposium 2021 Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-12-16 Minul Doluweera, Kiriheneappuhamilage Don Harindu Kusaljith Kirihene, Neluwa-Liyanage Ruwan Indika, Channa Nirmal Sirisena, Asel Helitha Jatunarachchi, Uthkarsha Chandrasena, Senumi Gihansa Dharmadasa, Amali Samaranayake, Vonara Gatharie Devendra, Vinudi Nimethma Edirisinghe, Thusharie Sugandhika Suresh, Sharmila Jayasena, Gracia Fe Budoy Yu, Crist John Pastor, Tharanga Thoradeniya
The Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) and the College of Biochemists of Sri Lanka (CBSL) organized a virtual education symposium in 2021 funded by the International Union of Biochemistry and Molecular Biology (IUBMB). The parallel session named “Students’ Perception” was attended by 188 participants from 11 countries. The main objectives of this session
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A challenge-based interdisciplinary undergraduate concept fostering translational medicine Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-27 Floris A. Valentijn, Michael Y. Schakelaar, Maria A. Hegeman, Willemijn D. Schot, Wim J. A. G. Dictus, Sandra Crnko, Toine ten Broeke, Niels Bovenschen
Translational medicine (TM) is an interdisciplinary branch of biomedicine that bridges the gap from bench-to-bedside to improve global health. Fundamental TM skills include interdisciplinary collaboration, communication, critical thinking, and creative problem-solving (4Cs). TM is currently limited in undergraduate biomedical education programs, with little patient contact and opportunities for collaboration
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The Universe Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-27 Joselyn Michelle Almeida, Andrés París-Muñoz
CONFLICT OF INTEREST STATEMENT There is no conflict of interest, nor are there grants or other funding to declare.
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An advanced course sequence in eukaryotic cell and molecular biology: A year-long course where active learning and peer-led groups resulted in higher learning gains and significant course passing scores Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-20 Julio G. Soto, Rachael French, Sulekha Anand
We developed an advanced, year-long course sequence in eukaryotic cell and molecular biology in order to increase conceptual understanding. Three years of historical data from a one semester, traditional-lecture, senior cell and molecular biology course (n = 237) were compared with 3 years of data collected from the year-long course sequence (n = 176). There were significant content gains for the students
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DNA Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-20 Dipika Mishra
This year marks 70 years since the discovery of DNA, and this poem “DNA” is an attempt to make the general audience aware of the basic features of this macromolecule.
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Process oriented guided inquiry learning: A systematic review using bibliometric analysis Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-16 Şenol Şen
Process oriented guided inquiry learning (POGIL), is a group-learning method that contributes to the active participation of learners in learning/teaching environments. However, a standard process for using the POGIL in classes is not available. In addition, no systematic reviews using bibliometric analysis in the literature examine the studies concerning POGIL in terms of content and research trends
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Demystifying dimensionality reduction techniques in the ‘omics’ era: A practical approach for biological science students Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-08 Leonardo D. Garma, Nuno S. Osório
Dimensionality reduction techniques are essential in analyzing large ‘omics’ datasets in biochemistry and molecular biology. Principal component analysis, t-distributed stochastic neighbor embedding, and uniform manifold approximation and projection are commonly used for data visualization. However, these methods can be challenging for students without a strong mathematical background. In this study
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Embedding retrieval practice in undergraduate biochemistry teaching using PeerWise Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-06 Tanya Higgins, Ed Dudley, Owen Bodger, Phil Newton, Nigel Francis
Retrieval practice is an evidence-based approach to teaching; here, we evaluate the use of PeerWise for embedding retrieval practice into summative assessment. PeerWise allows anonymous authoring, sharing, answering, rating, and feedback on peer-authored multiple choice questions. PeerWise was embedded as a summative assessment in a large first-year introductory biochemistry module. Engagement with
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When online citizen science meets teaching: Storyfication of a science discovery game to teach, learn, and contribute to genomic research Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-11-06 Chrisostomos Drogaris, Alexander Butyaev, Elena Nazarova, Roman Sarrazin-Gendron, Harsh Patel, Akash Singh, Brenden Kadota, Jérôme Waldispühl
In the last decade, video games became a common vehicle for citizen science initiatives in life science, allowing participants to contribute to real scientific data analysis while learning about it. Since 2010, our scientific discovery game (SDG) Phylo enlists participants in comparative genomic data analysis. It is frequently used as a learning tool, but the activities were difficult to aggregate
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An ode on the odyssey of lipids Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-31 Anbalagan Anithasri
The poem Ode on the Odyssey of lipoproteins describes the structure, functions and metabolism of lipoproteins namely Chylomicrons, LDL, VLDL and HDL. This poem is a triolet with eight lines in each stanza. Odyssey is the travel experience of an adventurous journey when someone travels far and wide. This poem describes the transport adventures of Lipids when they travel in the form of lipoproteins.
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Online case-based learning for medical students as a teaching method for biochemistry at King Abdulaziz University amid COVID-19 pandemic (a study conducted in 2021) Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-18 Eman A. Kubbara, Nasreldin Marhoum Ahmed, Turki Alamri, Marwan A. Bakarman, Husam Malibary, Rasha Eid, Abdulrahman Omer Alzahrani
Online case-based learning (CBL) is a method used by King Abdulaziz University to teach medical students in their preclinical years. The use of CBL in basic sciences is important for enabling medical students to correlate basic sciences with future clinical practice. This study implemented online CBL for biochemistry teaching as part of the medical genetic module for 3rd-year preclinical students.
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An integrated laboratory work to improve students' practical skills and attitudes toward biochemistry in the biochemistry course Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-14 Yunita Arian Sani Anwar, Muti'ah Muti'ah, Yuli Kusuma Dewi
This research reports on implementing the integrated laboratory work to achieve effective learning in the biochemistry course. The integrated laboratory work includes three stages: pre-laboratory, lab work, and post-laboratory. In other words, the three stages include planning, implementing, and evaluating investigation activities in the laboratory. The research design used was a posttest control group
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A low-cost cure for CUREs: An undergraduate microbiology course engaging students in authentic research using publicly available datasets Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-12 Ognenka Avramovska, Megan E. Rokop
Undergraduate research experiences are key to preparing STEM students for a range of careers and graduate programs, and to impacting retention in STEM. Providing undergraduate research experiences can be challenging for institutions due to the high cost associated with equipment and reagents, lab space, and research mentors. In this study, we present an upper-level microbiology seminar course that
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An idea to explore: Determination of single nucleotide polymorphisms in alcohol metabolism-related genes using PCR-based assays to understand the link between an individual's genotype and phenotype Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-10 Naoto Shirasu, Shin'ichiro Yasunaga
Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely allele-specific (AS) PCR and a PCR-restriction fragment polymorphism (RFLP) analysis
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Evolution of a self-renewing, participant-centered workshop series in BMB assessment Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-10 Ludmila Tyler, Peter J. Kennelly, Shelly Engelman, Kirsten F. Block, Jennifer C. Bobenko, Jaclyn Catalano, Jesica A. Jones, Margaret I. Kanipes-Spinks, Yang Mooi Lim, Jennifer Loertscher, Tejiri Olafimihan, Hailey Reiss, Territa L. Upchurch-Poole, Yufeng Wei, Kimberly J. Linenberger Cortes, Victoria Del Gaizo Moore, Daniel R. Dries
We present as a case study the evolution of a series of participant-centered workshops designed to meet a need in the life sciences education community—the incorporation of best practices in the assessment of student learning. Initially, the ICABL (Inclusive Community for the Assessment of Biochemistry and Molecular Biology/BMB Learning) project arose from a grass-roots effort to develop material for
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E-learning and research experience exchange in the online setting of student peer mentor network during COVID-19 pandemic and beyond: A laboratory case study Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-09 Dorota Lubanska, Sami Alrashed, Lia Oschanney, Alan Cieslukowski, Ali Nadi, Philip Habashy, Adam Renaud, Antonio Roye-Azar, Mohamed Soliman, Kadila Adili, Allison Baker, Maliha Baseet, Amy Llancari, Aiden Mitrevski, Sahar Mouawad, Kim Nguyen, Alexandra Sorge, Katie Zuccato, Emmanuel Boujeke, Jason Cala, Stephanie Dinescu, Marissa Ho, Almas Khan, Deya'a Almasri, Daniel Dunn, Hasan Ghafoor, Eddie Grimmett
For close to 2 years, we have witnessed the impacts of the SARS-CoV-2 pandemic on research at several different levels. Among the list, limited access to laboratory-based training for undergraduate students prevented this cohort from gaining exposure to the realities of a research laboratory at a critical time in training when they may have found motivation in this area as a career. COVID exposed a
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An online research immersion program to increase introductory science student confidence and science identity Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-09 Erica J. Zheng, Elizabeth Oakes, Julie Roden
The number of undergraduate students from underrepresented backgrounds enrolled in science and technology-related courses has increased over the past 20 years, but these students' persistence in STEM majors until graduation still lags behind the overall college population. Interventions like exposure to independent research, instruction using active learning, and connection within a scientific community
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A cord of four strands: Perspective of pre-medical and medical students on combined teaching modalities in undergraduate biochemistry Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-04 Simeon Andrews, Pradipta Paul, Ali Chaari
Despite being a traditional coursework for pre-medical and medical students around the globe, biochemistry education suffers from a lack of positive appreciation due to the nature of the subject combined with deficiency of teaching modalities. A first semester biochemistry course was designed to include four different teaching modalities: lectures, recitations, case studies, and student presentations
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Modeling in molecular genetics allows students to make connections between biological scales Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-10-04 Kristy J. Wilson, Allison K. Chatterjee
Students often see college courses as the presentation of disconnected facts, especially in the life sciences. Student-created Structure Mechanism/Relationship Function (SMRF) models were analyzed to understand students' abilities to make connections between genotype, phenotype, and evolution. Students were divided into two sections; one section received instructions that included a specific gene as
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Importance of three physiological models for teaching the carbohydrates metabolism Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-18 Sofía Judith Garófalo, Lydia Galagovsky, Manuel Alonso
In this work extensive misconceptions of university students' —from nutrition area— about the metabolism of carbohydrates (CHM) in the human organism have been documented. The results lead to consider their difficulties concerning the learning of a complex set of imbricated biochemical models involved. Pursuant to these considerations, three physiological models are proposed as conceptual axes around
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Learning by teaching efficiently enhances learning outcomes in molecular biology of the cell course Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-15 Ivan Mijakovic, Shadi Rahimi
To evaluate the impact of active learning approaches in a basic molecular and cell biology course for undergraduate students, we assessed the effect of learning by teaching and peer review on the learning outcomes. A literature seminar activity with peer review and feedback was organized as a compulsory activity for all students, covering about 25% of the course content. The remaining 75% of the course
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CUR(E)ating a new approach to study fungal effectors and enhance undergraduate education through authentic research Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-13 Gengtan Li, Mai McWilliams, Matheus Rodrigues, Benjamin Mearkle, Nader Jaafar, Vivek Golla, Houlin Yu, He Yang, Dilay Hazal Ayhan, Kelly Allen, Domingo Martínez-Soto, Amy Springer, Li-Jun Ma
Course-based Undergraduate Research Experiences (CUREs) integrate active, discovery-based learning into undergraduate curricula, adding tremendous value to Biochemistry and Molecular Biology (BMB) education. There are multiple challenges in transforming a research project into a CURE, such as the readiness of students, the time commitment of the instructor, and the productivity of the research. In
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Introducing high school biology students to biochemistry with a short, content-oriented module Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-08 Archer Harrold, Allison Cruikshank, Bryan Penas, Rebecca L. Roston
Many STEM disciplines are underrepresented to High School students. This is problematic as many students' decisions for college are shaped by their experiences and achievements in high school. Short content-oriented modules have been shown to encourage science identity and otherwise benefit the students' learning. Following the ASBMB's outreach protocol, we developed a short content-oriented module
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Drug design education in China Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-04 Wei Fu, Wei Li, Boyu Chen, Junjie Zhang, Qiong Xie, Lu Zhou, Xuemei Zhang
With the emergence of innovative technologies, including combinatorial chemistry, high-throughput screening, computer-aided drug design (CADD), artificial intelligence (AI) and big data, the importance of drug design in the field of drug discovery and development is increasing. Additionally, education in drug design plays an important role in the training of pharmaceutical talent. Starting with undergraduates
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Application and evaluation of nine-grid thinking model in biochemistry teaching Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-09-02 Yan Huang, Jinhong Pei, Junmei Wang, Xueqing Li, Yuna Li
Biochemistry is an important professional course to undergraduates majoring in rehabilitation therapy in medical colleges and universities. To deepen students' understanding of the taught content, enhance their application ability and cultivate their high-level thinking ability, we investigated the effect of integration of the nine-grid thinking model into the teaching process. With the inline and
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Redesigning a course based undergraduate research experience for online delivery Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-28 Allison Witucki, David W. Rudge, Brandy Pleasants, Peng Dai, Wendy S. Beane
The COVID-19 pandemic forced educators to teach in an online environment. This was particularly challenging for those teaching courses that are intended to support bench science research. This practitioner article tells the story of how an instructor transformed their Course-based Undergraduate Research Experience (CURE) using the Backwards Design Method into a synchronous online course. Research objectives
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Computer-aided drug design course for pharmacy major students in Shenyang Pharmaceutical University following the COVID-19 pandemic: Challenges and opportunities Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-25 Min Huang, Yue Du, Yajing Liu, Yanfang Zhao, Yongxue Guo, Dan Liu, Linxiang Zhao, Jian Wang
The computer-aided drug design (CADD) course that spans biochemistry, computational chemistry, medicinal chemistry, and other cutting-edge sciences is considered an important course by pharmaceutical universities in China. The course teaches students how drugs bind to protein targets and exert their biological activities using computer tools, and covers the basic principles of drug development and
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A project-oriented biochemistry laboratory for protein engineering and structure–function using small laccase enzyme from Streptomyces coelicolor Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-19 Arie Van Wieren, Philip Colen, Sudipta Majumdar
An understanding of structure–function relationships in proteins is essential for modern biochemical studies. The integration of common freely accessible bioinformatics tools available online with the knowledge of protein-engineering tools provide a fundamental understanding of the application of protein structure–function for biochemical research. In order for students to apply their prior knowledge
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Integrative teaching of metabolic modeling and flux analysis with interactive python modules Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-16 Joshua A. M. Kaste, Antwan Green, Yair Shachar-Hill
The modeling of rates of biochemical reactions—fluxes—in metabolic networks is widely used for both basic biological research and biotechnological applications. A number of different modeling methods have been developed to estimate and predict fluxes, including kinetic and constraint-based (Metabolic Flux Analysis and flux balance analysis) approaches. Although different resources exist for teaching
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A collaborative approach to promote use of 3D printing in a biology research laboratory Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-16 Jenny Wong-Welch, Richard M. Cripps
Three dimensional (3D) design and printing are customizable and cost-effective approaches to developing small equipment and other items for use in various interdisciplinary applications. However, many pedagogical approaches to 3D printing focus more on the generation of artifacts than on the involvement of students as creators. Moreover, library makerspaces offer 3D printing services but cannot always
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Making creativity explicit: A workshop to foster creativity in biomedical science education Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-14 Alice M. Kim, Jessica A. Gibbons, Caroline J. Speed, Janet O. Macaulay
Previously we identified that biomedical science students commonly misunderstand “creativity,” mistaking it for “freedom.” In the present study, we describe and evaluate a workshop designed to increase students' awareness of creativity as a highly sought-after employability skill and cognitive process applicable to scientific endeavors. To achieve this, we developed and introduced students to a process
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Use of mobile learning applications as an innovative method for the teaching of biochemistry Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-14 Aaser M. Abdelazim, Dalia A. Gaber, Khalid M. Adam, Ayman M. El-Ashkar, Hany W. Abdelmalak
Traditional teaching methods of biochemistry provide effective tools for knowledge transmission, but are considered less engaging with students. Smartphone applications may provide suitable alternatives to compensate for the shortcomings of traditional teaching methods.
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Problem-based learning (PBL) application in ‘metabolic syndrome (MetS)’ among common diseases of the modern age: A case study Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-08-11 Tuğçe Günter
The present study was to teach metabolic syndrome (MetS) disease through a scenario developed according to the problem-based learning (PBL) approach in the biochemistry class. The study was designed as a single group pre-test and post-test research. The study group consisted of first-year students (N = 183) from the nursing department within the health sciences faculty of a state university in Turkey
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Demystifying PCR tests, challenges, alternatives, and future: A quick review focusing on COVID and fungal infections Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-24 Muhammad Sajeer Paramabth, Manoj Varma
The polymerase chain reaction (PCR) technique is one of the most potent tools in molecular biology. It is extensively used for various applications ranging from medical diagnostics to forensic science and food quality testing. This technique has facilitated to survive COVID-19 pandemic by identifying the virus-infected individuals effortlessly and effectively. This review explores the principles, recent
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Beating heart cells: Using cultured cardiomyocytes to study cellular structure and contractility in laboratory exercises Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-24 Stephen E. Asmus, Collin K. Wells, Hanna M. Montalvo
Heart muscle cells, or cardiomyocytes, exhibit intrinsic contractility in vitro. We found that commercially-available mammalian cardiomyocytes serve as an excellent model system for studying the cytoskeleton and cellular contractility, fundamental topics in undergraduate cell and molecular biology courses. Embryonic rat cardiomyocytes were plated on cell culture dishes or glass coverslips and visualized
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An idea to explore: Engaging high school students in structure-function studies of bacterial sortase enzymes and inhibitors - A comprehensive computational experimental pipeline Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-18 Shivani Godse, Tanvi Sapar, Jeanine F. Amacher
High school science fairs provide an exceptional opportunity for students to gain experience with scientific research, and participation has positive outcomes with respect to chosen careers in the sciences. However, it can be challenging to engage high school students in university-level research outside of formal internship programs. Here, we describe an experimental pipeline for a computational structural
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An educational visual resource to support understanding of liquid–liquid phase separation Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-14 Margot Riggi, Janet H. Iwasa
In collaboration with educators and researchers, we created an online resource called Phase Separation 101 to help undergraduate students understand the basics of liquid–liquid phase separation, an emerging and complex concept in cell biology for which visual resources are still scarce. This work presents the workflow and visual communication strategies that we followed to build scientifically accurate
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Identifying new small proteins through a molecular biology course-based undergraduate research experience laboratory class Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-12 Rommel J. Miranda, Cheryl Warren, Kathryn Mcdougal, Steven Kimble, Joseph Sanchez, Leann Norman, Virginia Anderson, Matthew Hemm
We developed a curriculum for an upper-level molecular biology course-based undergraduate research laboratory class funded by a National Science Foundation CAREER grant that focuses on identifying new small proteins in the bacterium, Escherichia coli. Our CURE class has been continually offered each semester for the last 10 years, with multiple instructors collaboratively developing and implementing
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An idea to explore: Introduction to research methods Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-11 Urmimala Basu
A curriculum description of a general introductory biology course titled “Introduction to Research Methods” is presented here. The course aims to provide a glimpse of biomedical research to students who have had no or limited exposure to research to encourage them to do research as freshmen. Thus, this course aims to better equip and invoke interest of high school and college students to undertake
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Change and challenge: An online course in Medical Biochemistry and Molecular Biology Biochem. Mol. Biol. Educ. (IF 1.4) Pub Date : 2023-07-06 Dan Zhong, Yang-Wuyue Liu, Gang Huang, Zhizhen Xu, Yuanyin Zhao, Wenhui He, Jianbin Sun, Fengtian He, Shan Chen, Shuang-Shuang Dai
The development of information technology and portable devices has sparked a revolution in the field of education, facilitating access to diverse educational resources and lifelong learning. In particular, the COVID-19 pandemic has accelerated the transition from face-to-face to distance teaching, which requires online education to be provided worldwide. Biochemistry and Molecular Biology are key basic