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Individual differences in hormonal responsiveness to social encounters: Commentary on Félix et al., 2020 and review of pertinent issues Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Kathleen V. Casto; David A. Edwards
The results of a recent study, Félix et al., 2020, give new information about the behavioral and endocrine correlates of individual differences in the potential for androgen response in male cichlid fish. We think the study raises issues that are pertinent to the study of hormones and competition in other species, particularly humans. Focusing mostly on androgen reactivity to social challenge, we emphasize
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Convergent neuroendocrine mechanisms of social buffering and stress contagion Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Natanja F. Peen; Natalia Duque-Wilckens; Brian C. Trainor
Social interactions play a key role in modulating the impact of stressful experiences. In some cases, social interactions can result in social buffering, the process in which the presence of one individual reduces the physiological and behavioral impact of stress in another individual. On the other hand, there is growing evidence that a key initiating factor of social buffering behaviors is the initiation
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The serotonin 1A receptor modulates the social behaviour within groups of a cooperatively-breeding cichlid Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Pia R. Stettler; Diogo F. Antunes; Barbara Taborsky
The neurotransmitter serotonin (5-HT) reduces aggressive behaviour in a number of vertebrates, and the 5-HT1A receptor is known to be involved in this regulation. However, the role of this receptor in the modulation of sociopositive behaviour remains largely unknown. Here we investigated the role of the 5-HT1A receptor in the regulation of aggressive, submissive and affiliative behaviour in the co
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Assessment of autism-relevant behaviors in C57BKS/J leptin receptor deficient mice Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Susan M. Greene; Yatzil R. Sanchez; Nikhita Pathapati; Gianna N. Davis; Georgianna G. Gould
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Oxytocin intensifies the mortality salience effect: Novel evidence for the social salience model of oxytocin Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Jun Chen; Yu L.L. Luo; Yiping Xie; Ziyan Yang; Huajian Cai
Oxytocin plays an important role in human responses to threat processing. Few studies have directly examined the effects of oxytocin on our response to death-related stimuli. In the current study, 63 participants intranasally received either 32 IU of oxytocin or a placebo and thereafter completed a visual dot-probe task consisting of death-related and non-death related images. The results indicated
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An examination of the influence of prenatal sex hormones on handedness: Literature review and amniotic fluid data Horm. Behav. (IF 3.684) Pub Date : 2021-01-20 Gareth Richards; Tess Beking; Baudewijntje P.C. Kreukels; Reint H. Geuze; Alan A. Beaton; Ton Groothuis
Competing theories have posited roles for foetal androgen exposure in the development of human handedness. However, due to practical and ethical considerations, few studies have used hormonal measures to examine this possibility. The current paper reviews this literature and reveals a generally inconsistent pattern of results. We also present data from a longitudinal study of prenatal sex hormone exposure
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Anxiety and depressive symptoms effects on cortisol trajectories from pregnancy to postpartum: Differences and similarities between women and men Horm. Behav. (IF 3.684) Pub Date : 2021-01-14 Ana Conde; Raquel Costa; Bárbara Figueiredo
Anxiety and depressive symptoms may influence cortisol trajectories in women and men during pregnancy and the postpartum period. Using a multilevel approach, anxiety and depressive symptoms effects on 24-hour urinary free cortisol trajectories from the 2nd trimester to 3-months postpartum were examined in a sample of 66 women and 65 men with no known psychosocial or medical risk (N = 131; 33 (50%)
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A longitudinal evaluation of ovulatory cycle shifts in women's mate attraction and preferences Horm. Behav. (IF 3.684) Pub Date : 2021-01-06 Julia Stern; Tobias L. Kordsmeyer; Lars Penke
Are ovulatory cycle shifts in women's mate attraction and preferences robust? What are underlying mechanisms of potential cycle shifts? These questions are the subject of a current scientific debate surrounding the good genes ovulatory shift hypothesis. Here, we report a large, preregistered, within-subjects study, including salivary hormone measures and conception risk estimates based on luteinizing
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Variation in aggression rates and urinary cortisol levels indicates intergroup competition in wild bonobos Horm. Behav. (IF 3.684) Pub Date : 2020-12-30 Leveda Cheng; Stefano Lucchesi; Roger Mundry; Liran Samuni; Tobias Deschner; Martin Surbeck
Intergroup competition is a widespread phenomenon across taxa and groups typically compete over access to limited resources, such as food and mates. Such competition may be quantified by changes in individuals' behavioral and physiological status in response to intergroup encounters (IGEs). Bonobos, one of our closest living relatives, are often regarded as xenophilic and exhibit high tolerance towards
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Preliminary evidence that oxytocin does not improve mentalizing in women with schizophrenia Horm. Behav. (IF 3.684) Pub Date : 2020-12-28 Ellen R. Bradley; Marlene Tai; Michael Hankin; Joshua D. Woolley
Introduction Mentalizing, the ability to infer other people's intentions and emotions, is commonly impaired in schizophrenia and may represent an endophenotype. The hypothalamic neuropeptide oxytocin has been shown to improve mentalizing in men with schizophrenia, but its effects in women remain unclear. Given sex differences in the clinical manifestations of schizophrenia and oxytocin system function
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Effects of testosterone therapy on constructs related to aggression in transgender men: A systematic review Horm. Behav. (IF 3.684) Pub Date : 2020-12-24 Tine Taulbjerg Kristensen; Louise Lehmann Christensen; Jan Frystyk; Dorte Glintborg; Guy T'Sjoen; Kirsten K. Roessler; Marianne Skovsager Andersen
Background Transgender men are assigned female sex at birth, but identify as men. The anabolic and androgenic sex hormone testosterone has been positively associated with aggression. Therefore, transgender men are warned of increasing aggression when initiating testosterone therapy. Aim To explore the literature regarding the effects of testosterone therapy on aggression-related constructs in transgender
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Exogenous leptin promotes reproductive behavior during aphagia in red-sided garter snakes (Thamnophis sirtalis parietalis) Horm. Behav. (IF 3.684) Pub Date : 2020-12-24 Rachel C. Wilson; Michael P. LeMaster; Deborah I. Lutterschmidt
Despite the established dichotomy between investment in either reproduction or self-maintenance, a hormonal mechanism that influences an organism's decision to prioritize these behaviors remains elusive. The protein hormone leptin is a likely candidate because it is secreted from adipocytes in proportion to the amount of stored fat in numerous species. Although the majority of studies suggest that
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Breeding at higher latitude is associated with higher photoperiodic threshold and delayed reproductive development in a songbird Horm. Behav. (IF 3.684) Pub Date : 2020-12-17 D. Singh; S.M. Reed; A.A. Kimmitt; K.A. Alford; C.A. Stricker; P.D. Polly; E.D. Ketterson
Many seasonally breeding animals exhibit a threshold day length (critical photoperiod; CPP) for gonadal growth, and populations breeding at higher latitudes typically have a higher CPP. Much less is known about latitudinal variation in CPP in migratory population that winter away from their breeding range and must time their reproduction to match favorable conditions at their destination. To address
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Acute aggressive behavior perturbates the oxidative status of a wild bird independently of testosterone and progesterone Horm. Behav. (IF 3.684) Pub Date : 2020-12-16 Lucia Mentesana; Nicolas M. Adreani
Aerobically demanding activities like aggression can lead to an elevated oxidative metabolism affecting the concentration of pro-oxidant and antioxidant compounds and can result in an overall perturbation of the oxidative status. Aggression may also alter the oxidative status indirectly through an increase in testosterone and progesterone concentrations. Given that changes in the oxidative status could
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Early social experience has life-long effects on baseline but not stress-induced cortisol levels in a cooperatively breeding fish Horm. Behav. (IF 3.684) Pub Date : 2020-12-17 Diogo F. Antunes; Maria Reyes-Contreras; Gaétan Glauser; Barbara Taborsky
In cooperatively breeding cichlid fish, the early social environment has lifelong effects on the offspring's behaviour, life-history trajectories and brain gene expression. Here, we asked whether the presence or absence of parents and subordinate helpers during early life also shapes fluctuating levels of cortisol, the major stress hormone in the cichlid Neolamprologus pulcher. To non-invasively characterize
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Endogenous variation in estradiol in women affects the weighting of metric and categorical information in spatial location memory Horm. Behav. (IF 3.684) Pub Date : 2020-12-13 Mark P. Holden; Elizabeth Hampson
Recent work has suggested that sex differences may exist in the strategies or types of cues that are utilized by men and women to remember discrete spatial locations or routes through a visual environment. The current study investigated the effects of circulating estradiol levels in women on the relative weighting of categorical versus fine-grained ‘metric’ information in a test of short-term memory
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No evidence for a difference in 2D:4D ratio between youth with elevated prenatal androgen exposure due to congenital adrenal hyperplasia and controls Horm. Behav. (IF 3.684) Pub Date : 2020-12-09 Gideon Nave; Christina M. Koppin; Dylan Manfredi; Gareth Richards; Steven J. Watson; Mitchell E. Geffner; Jillian E. Yong; Robert Kim; Heather M. Ross; Monica Serrano-Gonzalez; Mimi S. Kim
The second-to-fourth digit ratio (2D:4D) has been associated with sexual dimorphism, with a lower 2D:4D in males. A large body of research has relied on the 2D:4D as a proxy for prenatal androgen exposure, and includes reports of relationships between 2D:4D and a wide range of human traits. Here, we examine the validity of the 2D:4D proxy by studying the association between 2D:4D and classical Congenital
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Sex steroids modulate circadian behavioral rhythms in captive animals, but does this matter in the wild? Horm. Behav. (IF 3.684) Pub Date : 2020-11-29 Emily K. Elderbrock; Michaela Hau; Timothy J. Greives
Nearly all organisms alter physiological and behavioral activities across the twenty-four-hour day. Endogenous timekeeping mechanisms, which are responsive to environmental and internal cues, allow organisms to anticipate predictable environmental changes and time their daily activities. Among-individual variation in the chronotype, or phenotypic output of these timekeeping mechanisms (i.e. timing
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Disruption of global hypothalamic microRNA (miR) profiles and associated behavioral changes in California mice (Peromyscus californicus) developmentally exposed to endocrine disrupting chemicals Horm. Behav. (IF 3.684) Pub Date : 2020-11-30 Sarabjit Kaur; Jessica A. Kinkade; Madison T. Green; Rachel E. Martin; Tess E. Willemse; Nathan J. Bivens; A. Katrin Schenk; William G. Helferich; Brian C. Trainor; Joseph Fass; Matthew Settles; Jiude Mao; Cheryl S. Rosenfeld
Developmental exposure to endocrine disrupting chemicals (EDCs), e.g., bisphenol A (BPA) or genistein (GEN), causes longstanding epigenome effects. MicroRNAs (miRs) regulate which mRNAs will be translated to proteins and thereby serve as the final checkpoint in epigenetic control. Scant amount is known, however, whether EDCs affect neural miRNA (miR) patterns. We aimed to test the hypothesis that developmental
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Arginine vasotocin affects vocal behavior but not selective responses to conspecific calls in male túngara frogs Horm. Behav. (IF 3.684) Pub Date : 2020-11-27 Nicole M. Kime; Sandra Goutte; Michael J. Ryan
Arginine vasotocin (AVT) and its homolog arginine vasopressin (AVP) modulate social behavior, including social communication. In anuran amphibians, male-male competition and female mate choice rely heavily on acoustic signaling. Behavioral experiments show that AVT influences motivation to call and vocal production. It may also influence how males process and respond to socially relevant auditory stimuli
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Effect of contact incubation on stress, behavior and body composition in the precocial Red jungle fowl Horm. Behav. (IF 3.684) Pub Date : 2020-11-26 Rie Henriksen; Ann-Charlotte Svensson Holm; Per Jensen
Birds use contact incubation to warm their eggs above ambient temperature required for embryonic development. In contrast, birds in the industry as well as many birds in breeding programs and scientific studies are incubated in conventional incubators that warm eggs via circulating warm air. This means that contact incubated eggs have different thermal properties than eggs incubated in a conventional
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Endocrine changes related to dog domestication: Comparing urinary cortisol and oxytocin in hand-raised, pack-living dogs and wolves Horm. Behav. (IF 3.684) Pub Date : 2020-11-26 G. Wirobski; F. Range; F.S. Schaebs; R. Palme; T. Deschner; S. Marshall-Pescini
Dogs are exceptionally well adapted to life close to humans, and alterations in their endocrine system during the domestication process may be an underlying mechanism. In particular, it has been suggested that low circulating cortisol concentrations in conjunction with simultaneously high oxytocin concentrations may have resulted in dogs' increased docility (‘selection for tameness’ hypothesis) and
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Relationships between ovarian hormone concentrations and mental rotations performance in naturally-cycling women Horm. Behav. (IF 3.684) Pub Date : 2020-11-23 Talia N. Shirazi; Kate Levenberg; Heather Cunningham; Heather Self; Khytam Dawood; Rodrigo Cárdenas; Triana L. Ortiz; Justin M. Carré; S. Marc Breedlove; David A. Puts
Circulating gonadal hormones have been linked to variation in the structure and function of the adult human brain, raising the question of how cognition is affected by sex hormones in adulthood. The impacts of progestogens and estrogens are of special interest due to the widespread use of hormone supplementation. Multiple studies have analyzed relationships between ovarian hormones and mental rotation
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Effects of ∆9-THC on memory in ovariectomized and intact female rats Horm. Behav. (IF 3.684) Pub Date : 2020-11-23 Alyssa F. DeLarge; Peter J. Winsauer
The effects of marijuana's major psychoactive cannabinoid, ∆9-tetrahydrocannibinol (∆9-THC), were examined on memory in female rats by training subjects to respond under a repeated acquisition and delayed-performance procedure. During this task, subjects acquired a different 4-response sequence each session, which was then recalled after a delay. Sequence retention was tested following various delays
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Functional differences in the hypothalamic-pituitary-gonadal axis are associated with alternative reproductive tactics based on an inversion polymorphism Horm. Behav. (IF 3.684) Pub Date : 2020-11-21 J.L. Loveland; L.M. Giraldo-Deck; D.B. Lank; W. Goymann; M. Gahr; C. Küpper
The evolution of social behavior depends on genetic changes, yet, how genomic variation manifests itself in behavioral diversity is still largely unresolved. Chromosomal inversions can play a pivotal role in producing distinct behavioral phenotypes, in particular, when inversion genes are functionally associated with hormone synthesis and signaling. Male ruffs exhibit alternative reproductive tactics
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Inhibition of progesterone receptor activity during development increases reelin-immunoreactivity in Cajal-Retzius cells, alters synaptic innervation in neonatal dentate gyrus, and impairs episodic-like memory in adulthood Horm. Behav. (IF 3.684) Pub Date : 2020-11-21 Andrew J. Newell; Sung Hwan Chung; Christine K. Wagner
Progesterone receptor (PR) is expressed in Cajal-Retzius (CR) cells of the dentate gyrus (DG) molecular layer during the postnatal period (P1–28), a critical stage of development for the dentate gyrus and its circuitry. CR cells secrete the glycoprotein, reelin, which is required for typical development of the DG and its connections, particularly afferent input from the perforant path. This pathway
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Annual regulation of adrenocortical function in migrant and resident subspecies of white-crowned sparrow Horm. Behav. (IF 3.684) Pub Date : 2020-11-19 Jesse S. Krause; Zoltán Németh; Jonathan H. Pérez; Helen E. Chmura; Karen R. Word; Hannah J. Lau; Ryan E. Swanson; Jeffrey C. Cheah; Lisa N. Quach; Simone L. Meddle; John C. Wingfield; Marilyn Ramenofsky
Corticosterone affects physiology and behavior both during normal daily processes but also in response to environmental challenges and is known to mediate life history trade-offs. Many studies have investigated patterns of corticosterone production at targeted times of year, while ignoring underlying annual profiles. We aimed to understand the annual regulation of hypothalamic-pituitary-adrenal (HPA)
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Prenatal androgen exposure and children's gender-typed behavior and toy and playmate preferences Horm. Behav. (IF 3.684) Pub Date : 2020-11-19 Debra Spencer; Vickie Pasterski; Sharon A.S. Neufeld; Vivette Glover; Thomas G. O'Connor; Peter C. Hindmarsh; Ieuan A. Hughes; Carlo L. Acerini; Melissa Hines
We report findings from two studies investigating possible relations of prenatal androgen exposure to a broad measure of children's gender-typed behavior, as well as specifically to children's toy and playmate preferences. Study 1 investigated these outcomes for 43 girls and 38 boys, aged 4 to 11 years, with congenital adrenal hyperplasia (CAH, a genetic condition causing increased adrenal androgen
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The effects of food supply on reproductive hormones and timing of reproduction in an income-breeding seabird Horm. Behav. (IF 3.684) Pub Date : 2020-11-11 Shannon Whelan; Scott A. Hatch; Z.M. Benowitz-Fredericks; Charline Parenteau; Olivier Chastel; Kyle H. Elliott
Current food supply is a major driver of timing of breeding in income-breeding animals, likely because increased net energy balance directly increases reproductive hormones and advances breeding. In capital breeders, increased net energy balance increases energy reserves, which eventually leads to improved reproductive readiness and earlier breeding. To test the hypothesis that phenology of income-breeding
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Activation of the amylin pathway modulates cocaine-induced activation of the mesolimbic dopamine system in male mice Horm. Behav. (IF 3.684) Pub Date : 2020-11-10 Aimilia Lydia Kalafateli; Cajsa Aranäs; Elisabet Jerlhag
Besides food intake reduction, activation of the amylin pathway by salmon calcitonin (sCT), an amylin and calcitonin receptor agonist, inhibits alcohol-mediated behaviors in rodents. This involves brain areas processing reward, i.e. the laterodorsal (LDTg), ventral tegmental area (VTA) and nucleus accumbens (NAc). However, the effects of stimulation of the amylin pathway on behaviors caused by cocaine
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Glucocorticoids do not promote prosociality in a wild group-living fish Horm. Behav. (IF 3.684) Pub Date : 2020-11-05 Brett M. Culbert; Isaac Y. Ligocki; Matthew G. Salena; Marian Y.L. Wong; Nicholas J. Bernier; Ian M. Hamilton; Sigal Balshine
Individuals often respond to social disturbances by increasing prosociality, which can strengthen social bonds, buffer against stress, and promote overall group cohesion. Given their importance in mediating stress responses, glucocorticoids have received considerable attention as potential proximate regulators of prosocial behaviour during disturbances. However, previous investigations have largely
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The role of dopamine signaling in prairie vole peer relationships Horm. Behav. (IF 3.684) Pub Date : 2020-11-05 Nicole S. Lee; Annaliese K. Beery
Dopamine signaling mediates the formation of some types of social relationships, including reproductive pair bonds in the socially monogamous prairie vole (Microtus ochrogaster). In addition to these pair bonds with mates, prairie voles demonstrate selective preferences for familiar same-sex peers. The dependence of peer relationships on dopamine signaling has not been tested, and the mechanisms supporting
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Alamandine through MrgD receptor induces antidepressant-like effect in transgenic rats with low brain angiotensinogen Horm. Behav. (IF 3.684) Pub Date : 2020-11-03 Ana F. Almeida-Santos; Leonardo A. de Melo; Sthéfanie C.A. Gonçalves; Laura B. Oliveira Amaral; Robson A.S. Santos; Maria José Campagnole-Santos; Lucas M. Kangussu
Alamandine (Ala1-Arg2-Val3-Tyr4-Ile5-His6-Pro7), a heptapeptide hormone of the renin–angiotensin system (RAS), exerts its effects through the Mas-related G-protein coupled receptor of the type D, MrgD, which is expressed in different tissues, including the brain. In the present study, we tested the hypothesis that alamandine could attenuate the depression-like behavior observed in transgenic rats with
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Functional neuroanatomy and neural oscillations during social eavesdropping in male golden hamsters Horm. Behav. (IF 3.684) Pub Date : 2020-11-04 Ching-Yi Liu; Wen-Sung Lai
Social eavesdropping is a low-cost learning mechanism by which individuals extract relevant social information from social interactions between conspecifics, thereby gaining subsequent advantages in information gathering and usage. The aim of this study was to take advantage of a new hamster model of social eavesdropping to investigate behavioral consequences and neural activity in male hamsters during
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Specificity in sociogenomics: Identifying causal relationships between genes and behavior Horm. Behav. (IF 3.684) Pub Date : 2020-11-02 Jenelys Ruiz-Ortiz; Jessica Tollkuhn
There has been rapid growth in the use of transcriptomic analyses to study the interplay between gene expression and behavior. Experience can modify gene expression in the brain, leading to changes in internal state and behavioral displays, while gene expression variation between species is thought to specify many innate behavior differences. However, providing a causal association between a gene and
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Sex-dependent effects of social status on the regulation of arginine-vasopressin (AVP) V1a, oxytocin (OT), and serotonin (5-HT) 1A receptor binding and aggression in Syrian hamsters (Mesocricetus auratus) Horm. Behav. (IF 3.684) Pub Date : 2020-11-01 Z.A. Grieb; A.P. Ross; K.E. McCann; S. Lee; M. Welch; M.G. Gomez; A. Norvelle; V. Michopoulos; K.L. Huhman; H.E. Albers
Dominance status in hamsters is driven by interactions between arginine-vasopressin V1a, oxytocin (OT), and serotonin 1A (5-HT1A) receptors. Activation of V1a and OT receptors in the anterior hypothalamus (AH) increases aggression in males, while decreasing aggression in females. In contrast, activation of 5-HT1A receptors in the AH decreases aggression in males and increases aggression in females
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Differential effects of progesterone on social recognition and the avoidance of pathogen threat by female mice Horm. Behav. (IF 3.684) Pub Date : 2020-10-19 Martin Kavaliers; Indra R. Bishnoi; Klaus-Peter Ossenkopp; Elena Choleris
Although pathogen threat affects social and sexual responses across species, relatively little is known about the underlying neuroendocrine mechanisms. Progesterone has been speculated to be involved in the mediation of pathogen disgust in women, though with mixed experimental support. Here we considered the effects of acute progesterone on the disgust-like avoidance responses of female mice to pathogen
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Oxytocin reverses ethanol consumption and neuroinflammation induced by social defeat in male mice Horm. Behav. (IF 3.684) Pub Date : 2020-10-19 M.D. Reguilón; C. Ferrer-Pérez; J. Miñarro; M. Rodríguez-Arias
Oxytocin (OXT) modulates social interactions, attenuates stressful responses and can decrease drug-seeking and taking behaviors. In previous studies, we observed that social defeat (SD) induced a long-lasting increase in ethanol intake and neuroinflammation in male mice. We also know that OXT blocks the increase in cocaine reward induced by SD. Therefore, in the present study we aimed to evaluate the
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Glutamate transporter-1 link astrocytes with heightened aggressive behavior induced by steroid abuse in male CF1 mice Horm. Behav. (IF 3.684) Pub Date : 2020-10-22 Marcelo S. Rodolphi; Afonso Kopczynski; Randhall B. Carteri; Monia Sartor; Fernanda U. Fontella; Marceli Feldmann; Gisele Hansel; Nathan R. Strogulski; Luis V. Portela
The astrocytic glutamate transporter GLT-1 performs glutamate uptake thereby mediating NMDAr responses in neurons. Ceftriaxone (CEF) upregulates astrocytic GLT-1 expression/activity, which could counteract excessive glutamate levels and aggressive behavior induced by anabolic synthetic steroids such as nandrolone decanoate (ND). Here, adult male CF-1 mice were allocated to oil (VEH), ND, CEF, and ND/CEF
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Exogenous testosterone decreases men's sensitivity to vocal cues of male dominance Horm. Behav. (IF 3.684) Pub Date : 2020-10-16 Chengyang Han; Christopher D. Watkins; Yu Nan; Jianxin Ou; Xue Lei; Xiangqian Li; Yin Wu
Assessing dominance is important for effective social interactions, and prior research suggests that testosterone is associated with men's dominance perceptions. The present study tested for a causal effect of exogenous testosterone on men's sensitivity to vocal cues of other men's dominance, an important parameter in male-male competition across species. One hundred and thirty-nine Chinese men received
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How to alleviate the agony of providing negative feedback: Emotion regulation strategies affect hormonal stress responses to a managerial task Horm. Behav. (IF 3.684) Pub Date : 2020-10-15 Christian L. Burk; Bettina S. Wiese
Providing negative feedback can be demanding, as it typically requires dealing with multiple negative emotions. The first aim of this study was to transfer this work-related task to a new laboratory protocol and to investigate short-term hormonal changes among feedback providers. The second aim was to test if such hormonal stress responses can be attenuated through a priori instructions on how to regulate
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Frank Beach Award Winner: Lessons from poison frogs on ecological drivers of behavioral diversification Horm. Behav. (IF 3.684) Pub Date : 2020-10-14 Lauren A. O'Connell
Variation in natural behavior is tightly linked to the ecological resources with which they co-evolved. This review discusses poison frog behavior and neuroendocrinology to illustrate how ecological factors drive diversification of behavior and its underlying neural mechanisms. Poison frogs show tremendous diversity in reproductive strategies that are tightly linked to water resources in their environment
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Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques Horm. Behav. (IF 3.684) Pub Date : 2020-10-14 Desirée De Leon; Shota Nishitani; Hasse Walum; Kai M. McCormack; Mark E. Wilson; Alicia K. Smith; Larry J. Young; Mar M. Sanchez
Oxytocin (OXT) and its receptor (OXTR) are encoded by OXT and OXTR, respectively. Variable methylation of these genes has been linked to variability in sociability and neuroendophenotypes. Here we examine whether OXTR or OXT methylation in blood predicts concentrations of OXT in cerebrospinal fluid (CSF) (n = 166) and social behavior (n = 207) in socially-housed female rhesus macaques. We report a
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Early experience alters developmental trajectory of central oxytocin systems involved in hypothalamic-pituitary-adrenal axis regulation in Long-Evans rats. Horm. Behav. (IF 3.684) Pub Date : 2020-10-09 Hannah E Lapp,Andrew A Bartlett,Susan L Zup,Richard G Hunter,Celia L Moore
Oxytocin is important for postnatal developmental experiences for mothers, infants, and transactions between them. Oxytocin is also implicated in adult affiliative behaviors, including social buffering of stress. There is evidence for connections between early life experience and adult oxytocin system functioning, but effects of early experience on behavioral, endocrine, and neurophysiological outcomes
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A longitudinal investigation of bidirectional and time-dependent interrelationships between testosterone and training motivation in an elite rugby environment Horm. Behav. (IF 3.684) Pub Date : 2020-10-09 Blair T. Crewther; Martin Hecht; Neill Potts; Liam P. Kilduff; Scott Drawer; Elizabeth Marshall; Christian J. Cook
In sport, testosterone has been positioned as a substrate for motivation with both directional and time dependencies. However, evidence is scarce when considering the complexities of competitive sport and no work has explicitly modeled these dependencies. To address these gaps, we investigated the bidirectional and time-dependent interrelationships between testosterone and training motivation in an
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Digit ratio (2D:4D) and congenital adrenal hyperplasia (CAH): Systematic literature review and meta-analysis Horm. Behav. (IF 3.684) Pub Date : 2020-10-06 Gareth Richards; Wendy V. Browne; Ezra Aydin; Mihaela Constantinescu; Gideon Nave; Mimi S. Kim; Steven J. Watson
The ratio of length between the second and fourth fingers (2D:4D) is commonly used as an indicator of prenatal sex hormone exposure. Several approaches have been used to try to validate the measure, including examining 2D:4D in people with congenital adrenal hyperplasia (CAH), a suite of conditions characterised by elevated adrenal androgen production secondary to defective steroidogenesis. We present
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Acute exposure of rats to a severe stressor alters the circadian pattern of corticosterone and sensitizes to a novel stressor: Relationship to pre-stress individual differences in resting corticosterone levels Horm. Behav. (IF 3.684) Pub Date : 2020-10-06 Xavier Belda; Silvia Fuentes; Javier Labad; Roser Nadal; Antonio Armario
Traumatic events have been proposed to be associated with hypo-activity of the hypothalamic-pituitary-adrenal (HPA) axis, but data in animal models exposed to severe stressors are controversial and have important methodological concerns. Individual differences in resting or stress levels of corticosterone might explain some of the inconsistencies. We then studied this issue in male rats exposed to
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Galanin neuron activation in feeding, parental care, and infanticide in a mouthbrooding African cichlid fish Horm. Behav. (IF 3.684) Pub Date : 2020-10-05 Julie M. Butler; Erandi M. Herath; Arohan Rimal; Sarah M. Whitlow; Karen P. Maruska
Galanin is a conserved neuropeptide involved in parental care and feeding. While galanin is known to mediate parental care and infanticide in rodents, its role in parental care and feeding behaviors in other taxa, particularly fishes, remains poorly understood. Mouthbrooding is an extreme form of parental care common in fishes in which caregivers carry offspring in their buccal cavity for the duration
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How prior pair-bonding experience affects future bonding behavior in monogamous prairie voles. Horm. Behav. (IF 3.684) Pub Date : 2020-09-30 Kelsey J Harbert,Matteo Pellegrini,Katelyn M Gordon,Zoe R Donaldson
Monogamous prairie voles (Microtus ochrogaster) form mating-based pair bonds. Although wild prairie voles rarely re-pair following loss of a partner, laboratory studies have shown that previous pairing and mating does not negate the ability to form a new partner preference. However, little is known about how prior bond experience may alter the trajectory and display of a new pair bond. In the present
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Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats Horm. Behav. (IF 3.684) Pub Date : 2020-10-01 Clarissa M. Liu; Ted M. Hsu; Andrea N. Suarez; Keshav S. Subramanian; Ryan A. Fatemi; Alyssa M. Cortella; Emily E. Noble; Mitchell F. Roitman; Scott E. Kanoski
Oxytocin potently reduces food intake and is a potential target system for obesity treatment. A better understanding of the behavioral and neurobiological mechanisms mediating oxytocin's anorexigenic effects may guide more effective obesity pharmacotherapy development. The present study examined the effects of central (lateral intracerebroventricular [ICV]) administration of oxytocin in rats on motivated
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Oral contraceptive use, especially during puberty, alters resting state functional connectivity Horm. Behav. (IF 3.684) Pub Date : 2020-09-25 Rupali Sharma; Zhuo Fang; Andra Smith; Nafissa Ismail
Millions of women worldwide use oral contraceptives (OCs), often starting during puberty/adolescence. It is, however, unknown how OC use during this critical period of development affects the brain. The objective of the current study was to examine resting state functional connectivity (FC) in the default mode network (DMN), central executive network (CEN), salience network (SN), reward network (RN)
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Characterizing the effects of tonic 17β-estradiol administration on spatial learning and memory in the follicle-deplete middle-aged female rat. Horm. Behav. (IF 3.684) Pub Date : 2020-09-25 Stephanie V Koebele,Sarah E Mennenga,Mallori L Poisson,Lauren T Hewitt,Shruti Patel,Loretta P Mayer,Cheryl A Dyer,Heather A Bimonte-Nelson
17β-estradiol (E2)-containing hormone therapy is a safe, effective way to alleviate unwanted menopause symptoms. Preclinical research has focused upon the role of E2 in learning and memory using a surgically menopausal rodent model whereby the ovaries are removed. Given that most women retain their reproductive tract and undergo a natural menopause transition, it is necessary to understand how exogenous
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Endocrine stress responsivity and social memory in 3xTg-AD female and male mice: A tale of two experiments. Horm. Behav. (IF 3.684) Pub Date : 2020-09-23 Elizabeth T Nguyen,Din Selmanovic,Marissa Maltry,Rachel Morano,Ana Franco-Villanueva,Christina M Estrada,Matia B Solomon
Stress confers risk for the development and progression of Alzheimer's disease (AD). Relative to men, women are disproportionately more likely to be diagnosed with this neurodegenerative disease. We hypothesized that sex differences in endocrine stress responsiveness may be a factor in this statistic. To test this hypothesis, we assessed basal and stress-induced corticosterone, social recognition,
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Perinatal exposure to FireMaster® 550 (FM550), brominated or organophosphate flame retardants produces sex and compound specific effects on adult Wistar rat socioemotional behavior. Horm. Behav. (IF 3.684) Pub Date : 2020-09-23 Shannah K Witchey,Loujain Al Samara,Brian M Horman,Heather M Stapleton,Heather B Patisaul
Firemaster 550 (FM550) is a flame retardant (FR) mixture that has become one of the most commonly used FRs in household items such as foam-based furniture and baby products. Because this mixture readily leaches from products, contamination of the environment and human tissues is widespread. Prior work by us and others has reported sex-specific behavioral deficits in rodents and zebrafish following
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Inside the supergene of the bird with four sexes. Horm. Behav. (IF 3.684) Pub Date : 2020-09-19 Donna L Maney,Jennifer R Merritt,Mackenzie R Prichard,Brent M Horton,Soojin V Yi
The white-throated sparrow (Zonotrichia albicollis) offers unique opportunities to understand the adaptive value of supergenes, particularly their role in alternative phenotypes. In this species, alternative plumage morphs segregate with a nonrecombining segment of chromosome 2, which has been called a ‘supergene’. The species mates disassortatively with respect to the supergene; that is, each breeding
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Brain region-dependent alterations in polysialic acid immunoreactivity across the estrous cycle in mice. Horm. Behav. (IF 3.684) Pub Date : 2020-09-18 Laura L Giacometti,Fangyi Huang,Brianna S Hamilton,Jacqueline M Barker
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Synthetic female gonadal hormones alter neurodevelopmental programming and behavior in F1 offspring. Horm. Behav. (IF 3.684) Pub Date : 2020-09-17 Krassimira A Garbett,Tianbing Ding,John Allison,Carrie A Grueter,Brad A Grueter,Kevin G Osteen,Kim Strifert,J David Sweatt
The increased prevalence of neurodevelopmental disorders during the last half-century led us to investigate the potential for intergenerational detrimental neurodevelopmental effects of synthetic female gonadal hormones, typically used in contraceptive pills. We examined 3 separate cohorts of mice over the span of 2 years, a total of 150 female F0 mice and over 300 male and female rodents from their
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Energetics at the urban edge: Environmental and individual predictors of urinary C-peptide levels in wild chacma baboons (Papio ursinus). Horm. Behav. (IF 3.684) Pub Date : 2020-09-16 Ines Fürtbauer,Charlotte Christensen,Anna Bracken,M Justin O'Riain,Michael Heistermann,Andrew J King
As human-modified landscapes encroach into natural habitats, wildlife face a reduction in natural food sources but also gain access to calorie-rich, human-derived foods. However, research into the energetics of wildlife living within and adjacent to urban and rural landscapes is lacking. C-peptide - a proxy for insulin production and a diagnostic tool for assessing pancreatic function in humans and
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Leptin at birth and at age 7 in relation to appetitive behaviors at age 7 and age 10. Horm. Behav. (IF 3.684) Pub Date : 2020-09-09 Sarah Warkentin,Susan Carnell,Andreia Oliveira
Leptin contributes to the control of food intake and energy balance. However, its association with appetitive behaviors during childhood is not well understood. We aimed to investigate the association between leptin, assessed at birth and at 7 years of age (y), and appetitive behaviors assessed at 7 and 10 y. Children from a Portuguese cohort with assessment of leptin levels at birth from umbilical
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Intranasal vasopressin expedites dishonesty in women. Horm. Behav. (IF 3.684) Pub Date : 2020-09-08