The optoacoustic imaging (OAI) methods are rapidly evolving for resolving optical contrast in medical imaging applications. In practice, measurement strategies are commonly implemented under limited‐view conditions due to oversized image objectives or system design limitations. Data acquired by limited‐view detection may impart artifacts and distortions in reconstructed optoacoustic (OA) images. We

Solar radiation exposure is recognised to be a significant contributor to the development of skin cancer. Monitoring the simultaneous and consecutive mechanisms of interaction could provide a greater understanding of the process of photocarcinogenesis. This work presents an analysis of the biochemical and morphological changes occurring to immortalised human epithelial keratinocyte (HaCaT) cell cultures

In this work, diffuse near‐infrared light reflectance spectroscopy based on a single optical probe, contains central single collection fiber surrounded by a circular array of illumination fibers, was used to quantify cerebral tissue properties in ApoE knockout mice following Sarcopoterium spinosum treatment. Sarcopoterium spinosum, also known as Thorny burnet, is a Mediterranean plant widely used as

Photodynamic therapy (PDT) with Rose Bengal has previously achieved eradication of Trichophyton rubrum infections causing toenail onychomycosis, however, its antifungal activity against other clinically relevant dermatophytes has yet to be studied. Here, we test the efficacy of PDT using Rose Bengal (140 μM) and 532 nm irradiation (101 J cm−2) against Trichophyton mentagrophytes and Trichophyton interdigitale

We present a novel all‐fiber probe with 710‐μm outside diameter for combined optical coherence tomography and pH detection. In cancer surgery, a significant challenge is how to completely remove the malignant tumor without cutting too much normal tissue. The difference between cancer tissue and normal tissue not only lies in morphology and structure but also in tissue pH, where malignant tissue has

We evaluated the impact of light‐scattering effects on spatial resolution in different SWIR sub‐regions by analyzing two SWIR emissive phantoms made of PDMS‐gold nanoclusters (Au NCs) composite covered with mice skin, or capillary tubes filled with Au NCs or IRDye 800CW at different depth in intralipids and finally, after administration of the Au NCs intravenously in mice.

Skin fibrosis is a debilitating feature of several systemic and dermatologic diseases. While current treatment options carry significant risk of side effects and recurrence, high‐fluence light emitting diode‐generated red light (LED‐RL) is an alternative therapeutic that is safe, non‐invasive, and accessible. We previously demonstrated LED‐RL decreases fibroblast proliferation, a key pathogenic component

Optoacoustic tomography aims to reconstruct maps of the initial pressure rise induced by the absorption of light pulses in tissue. This reconstruction is an illconditioned and under‐determined problem, when the data acquisition protocol involves limited detection positions. The aim of the work is to develop an inversion method which integrates denoising procedure within the iterative model‐based reconstruction

Emerging evidence indicates the clinical benefits of photobiomodulation therapy (PBMT) in the management of skin and mucosal wounds. Here we decided to explore the effects of different regiments of PBMT on epithelial cells and stem cells, and the potential implications over the epigenetic circuitry during healing. Scratch‐wound migration, immunofluorescence (anti‐acetyl‐Histone H3, anti‐acetyl‐CBP/p300

Ex‐vivo confocal laser scanning microscopy (CLSM) provides rapid, high‐resolution imaging, fluorescence detection and digital hematoxylin‐eosin (H&E)‐like staining.

The sun protection factor (SPF) values are currently determined using an invasive procedure, in which the volunteers are irradiated with ultraviolet (UV) light. Non‐invasive approaches based on hybrid diffuse reflectance spectroscopy (HDRS) have shown a good correlation with conventional SPF testing. Here, we present a novel compact and adjustable DRS test system.