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When Pyro(ptosis) Meets Palm(itoylation) Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-03-04 Lu Jiang, Zirui Wang, Ting Xu, Leiliang Zhang
Pyroptosis, a programmed cell death process, is vital for the immune response against microbial infections and internal danger signals. Recent studies have highlighted the importance of protein palmitoylation, a modification that involves attaching palmitate to cysteine residues, in regulating key proteins involved in pyroptosis. Palmitoylation of cGAS at residue C474 by ZDHHC18 affects its enzymatic
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Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-02-28 Suling Xu, Qingqing Wang, Wenxue Ma
Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal arena for cancer therapeutics, where cytokines and soluble mediators emerge as double-edged swords in the fight against cancer. This review ventures beyond traditional perspectives, illuminating the nuanced interplay of these elements as both allies and adversaries in cancer dynamics. It critically evaluates the
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Semaphorins and the bone marrow microenvironment: new candidates that influence the hematopoietic system Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-02-27 Carlos Eduardo da Silva Gonçalves, Ricardo Ambrósio Fock
The bone marrow is a haven for hematopoietic and non-hematopoietic cells, creating complex micro-anatomical regions called niches. These distinct niches all participate in an intricate orchestra of cellular interactions that regulates the hematopoietic stem cell and its progenies. In this review, we provide a detailed description of the three most well-known bone marrow niches and their participation
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Targeting NKG2D/NKG2DL axis in multiple myeloma therapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-02-15 Zhaoyun Liu, Hao Wang, Hui Liu, Kai Ding, Hongli Shen, Xianghong Zhao, Rong Fu
Immune effector cells in patients with multiple myeloma (MM) are at the forefront of many immunotherapy treatments, and several methods have been developed to fully utilise the antitumour potential of immune cells. T and NK cell-derived immune lymphocytes both expressed activating NK receptor group 2 member D(NKG2D). This receptor can identify eight distinct NKG2D ligands (NKG2DL), including major
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Signaling crosstalk between mesenchymal stem cells and tumor cells: Implications for tumor suppression or progression Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-02-02 Mojtaba Taheri, Hossein Abdul Tehrani, Sadegh Dehghani, Alireza Rajabzadeh, Mona Alibolandi, Nina Zamani, Ehsan Arefian, Mohammad Ramezani
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Exogenous Drugs-Induced Mouse Models of Atopic Dermatitis Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-01-12 Rou Zheng, Yan Ren, Xinyue Liu, Canxia He, Hua Liu, Yixuan Wang, Jianing Li, Shuya Xia, Zhifang Liu, Yizhao Ma, Dianchen Wang, Suling Xu, Geng Wang, Na Li
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Therapeutic implications of the interplay between Interferons and ER in breast cancer Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-01-05 Nataša Todorović-Raković, Jonathan R Whitfield
The involvement of interferons (IFNs) in various diseases, including breast cancer, has sparked controversy due to their diverse roles in immunity and significant impact on pathological mechanisms. In the context of breast cancer, the heightened expression of endogenous IFNs has been linked to anti-tumor activity and a favorable prognosis for patients. Within the tumor tissue and microenvironment,
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Targeting Interleukin-17 in Radiation-Induced Toxicity and Cancer Progression Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-01-05 Piyush Baindara
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Navigating IL-6: From Molecular Mechanisms to Therapeutic Breakthroughs. Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2024-01-02 Akey Krishna Swaroop, Preeya Negi, Ayushi Kar, M Esakkimuthukumar, N Jawahar, P K Krishnan Namboori, S Jubie
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Regulation of Regulated Cell Death by Extracellular Vesicles in Acute Kidney Injury and Chronic Kidney Disease Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-31 Zixuan Zhou, Linru Shi, Binghai Chen, Hui Qian
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Myeloid-derived Growth Factor and its Effects on Cardiovascular and Metabolic Diseases Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-30 Jinling Xu, Yanzhuo Song, Sheng Ding, Weizhe Duan, Guangda Xiang, Zhongjing Wang
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Advances in Extracellular Vesicles as Mediators of Cell-to-Cell Communication in Pregnancy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-29 Soumyalekshmi Nair, Melissa Razo-Azamar, Nanthini Jayabalan, Louise T. Dalgaard, Berenice Palacios-González, Anne Sørensen, Ulla Kampmann, Aase Handberg, Flavio Carrion, Carlos Salomon
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Decoding the roles of heat shock proteins in liver cancer Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-26 Chen Sun, Qi Pan, Mingyang Du, Jiahe Zheng, Ming Bai, Wei Sun
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Unveiling Cytokine Charge Disparity as a Potential Mechanism for Immune Regulation Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-26 Jennifer M. Messina, Minghao Luo, Md Shanewaz Hossan, Hadil A. Gadelrab, Xiguang Yang, Anna John, Joel R. Wilmore, Juntao Luo
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Interleukin-33/serum stimulation-2 pathway: Regulatory mechanisms and emerging implications in immune and inflammatory diseases Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-14 Peng-yi He, Meng-yao Wu, Li-yu Zheng, Yu Duan, Qi Fan, Xiao-mei Zhu, Yong-ming Yao
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COVID-19: from emerging variants to vaccination Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-09 Thilini H. Senevirathne, Demi Wekking, Joseph W.R. Swain, Cinzia Solinas, Pushpamali De Silva
The vigorous spread of SARS-CoV-2 resulted in the rapid infection of millions of people worldwide and devastation of not only public healthcare, but also social, educational, and economic infrastructures. The evolution of SARS-CoV-2 over time is due to the mutations that occurred in the genome during each replication. These mutated forms of SARS-CoV-2, otherwise known as variants, were categorized
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Harnessing the Potential of CD40 Agonism in Cancer Therapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-12-04 Yang Zhou, Ann Richmond, Chi Yan
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The impact of COVID-19 on cancer patients Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-11-30 Demi Wekking, Thilini H. Senevirathne, Josie L. Pearce, Marco Aiello, Mario Scartozzi, Matteo Lambertini, Pushpamali De Silva, Cinzia Solinas
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Radiation-targeted immunotherapy: a new perspective in cancer radiotherapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-11-30 Lihui Xuan, Chenjun Bai, Zhao Ju, Jinhua Luo, Hua Guan, Ping-Kun Zhou, Ruixue Huang
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Progranulinopathy: A Diverse Realm of Disorders Linked to Progranulin Imbalances Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-11-11 Guiwu Huang, Jinlong Jian, Chuan-Ju Liu
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An Emerging Paradigm of CXCL12 Involvement in the Metastatic Cascade Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-10-31 Dimitra P. Anastasiadou, Agathe Quesnel, Camille L. Duran, Panagiota S. Filippou, George S. Karagiannis
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Immunosuppressive Tumor Microenvironment and Uterine Fibroids:Role in Collagen Synthesis Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-10-06 Eslam E. Abd EL-Fattah, Rachel Michel, Mostafa A. Borahay
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CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: biological and clinical aspects Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-10-05 Demi Wekking, Vera Piera Leoni, Matteo Lambertini, Mariele Dessì, Andrea Pretta, Andrea Cadoni, Luigi Atzori, Mario Scartozzi, Cinzia Solinas
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Bioengineering strategies to enhance the interleukin-18 bioactivity in the modern toolbox of cancer immunotherapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-28 Mojtaba Taheri, Hossein Abdul Tehrani, Fatemeh Daliri, Mona Alibolandi, Masoud Soleimani, Alireza Shoari, Ehsan Arefian, Mohammad Ramezani
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Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-10-01 Tao Ye, Wei-yan Tao, Xiao-yi Chen, Cheng Jiang, Bin Di, Li-li Xu
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Extracellular vesicles in cardiovascular diseases: From pathophysiology to diagnosis and therapy Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-28 Yuxin Du, Lin Wu, Litao Wang, Russel J. Reiter, Gregory Y.H. Lip, Jun Ren
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The odyssey of cGAS: From cytosol to nucleus Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-27 Wenzhuo Hao, Wenjun Li, Lingyan Wang, Shitao Li
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Unravelling the immunobiology of innate lymphoid cells (ILCs): Implications in health and disease Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-16 Rupesh K. Srivastava, Leena Sapra, Asha Bhardwaj, Pradyumna K. Mishra, Bhupendra Verma, Zainab Baig
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Protein-protein interactions and related inhibitors involved in the NLRP3 inflammasome pathway Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-16 Zhen-yu Ma, Cheng Jiang, Li-li Xu
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Extracellular vesicles in cancer: Shaping the intricate network of metabolic reprogramming and immune interactions in the tumor microenvironment Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-09-15 Elisa Giovannetti, Tian Li
Abstract not available
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Exosome-mediated metabolic reprogramming: Implications in esophageal carcinoma progression and tumor microenvironment remodeling Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-30 Yong Xi, Yaxing Shen, Lijie Chen, Lijie Tan, Weiyu Shen, Xing Niu
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The cytokine trio - visfatin, placental growth factor and fractalkine – and their role in myocardial infarction with non-obstructive coronary arteries (MINOCA) Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-25 Aleksandra Stangret, Weronika Dykacz, Konrad Jabłoński, Aleksandra Wesołowska, Dominika Klimczak-Tomaniak, Janusz Kochman, Mariusz Tomaniak
Myocardial infarction with nonobstructive coronary arteries (MINOCA) remains a puzzling clinical entity. It is characterized by clinical evidence of myocardial infarction (MI) with normal or near-normal coronary arteries in angiography. Given the complex etiology including multiple possible scenarios with varied pathogenetic mechanisms, profound investigation of the plausible biomarkers of MINOCA may
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The critical role of osteopontin (OPN) in fibrotic diseases Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-23 Ziyi Tang, Zijing Xia, Xiangpeng Wang, Yi Liu
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Role of lipid signalling in extracellular vesicles-mediated cell-to-cell communication Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-23 Jordan Fyfe, Ilaria Casari, Marcello Manfredi, Marco Falasca
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Multifaceted role of CD14 in innate immunity and tissue homeostasis Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-23 Kunhee Na, Byung-Chul Oh, YunJae Jung
CD14 is a co-receptor of Toll-like receptor (TLR)− 4, with a critical role in innate immune responses. CD14 recognizes bacterial lipopolysaccharides, pathogen-, and damage-associated molecular patterns, thereby facilitating inflammatory immune responses. In addition to its well-established association with TLR4, CD14 is also implicated in TLR4-independent signaling, which leads to the apoptotic death
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Ferroptosis in Cancer Immunity and Immunotherapy: Multifaceted Interplay and Clinical Implications Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-20 Xiaoqian Zhai, Yiyun Lin, Lingling Zhu, Yuqing Wang, Jiabi Zhang, Jiewei Liu, Lu Li, Xiaojie Lu
Ferroptosis is a type of cell death characterized by iron-dependent phospholipid peroxidation and reactive oxygen species overproduction. Ferroptosis induces immunogenic cell death and elicits anti-tumor immune responses, playing an important role in cancer immunotherapy. Ferroptosis suppression in cancer cells impairs its immunotherapeutic efficacy. To overcome this issue, ferroptosis inducers (FINs)
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Extracellular vesicles as a novel mediator of interkingdom communication Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-21 Jumin Huang, Xuanrun Wang, Ziming Wang, Liyan Deng, Yuwei Wang, Yuping Tang, Lianxiang Luo, Elaine Lai-Han Leung
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Proteomics analysis of circulating small extracellular vesicles: Focus on the contribution of EVs to tumor metabolism Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-19 Federica Anastasi, Asia Botto, Benoit Immordino, Elisa Giovannetti, Liam A. McDonnell
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Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-12 Xinyu Tian, Ting Wang, Han Shen, Shengjun Wang
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Extracellular vesicles: Emerging mediators of cell communication in gastrointestinal cancers exhibiting metabolic abnormalities Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-06 Ghazaleh Pourali, Nima Zafari, Hamid Fiuji, Jyotsna Batra, Elham Nazari, Majid Khazaei, Seyed Mahdi Hassanian, Mahrou Vahabi, MohammadAli Kiani, Majid Ghayour-Mobarhan, Godefridus J. Peters, Gordon A. Ferns, Alfred King-yin Lam, Elisa Giovannetti, Amir Avan
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Liquid biopsy analysis of lipometabolic exosomes in pancreatic cancer Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-02 Wei Guo, Peiyao Ying, Ruiyang Ma, Zuoqian Jing, Gang Ma, Jin Long, Guichen Li, Zhe Liu
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Exosomes as a modulator of immune resistance in human cancers Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-08-02 Lanzhou Li, Chunyue Wang, Qiucheng Li, Yue Guan, Xin Zhang, Fange Kong, Zixin Feng, Yuanjun Lu, Di Wang, Ning Wang
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The role of microglial activation on ischemic stroke: Modulation by fibroblast growth factors Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-31 Confidence Dordoe, Wenting Huang, Canol Bwalya, Xue Wang, Bixin Shen, Hao Wang, Jing Wang, Shasha Ye, Peng Wang, Bao Xiaoyan, Xiaokun Li, Li Lin
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Role of exosomes in transferring chemoresistance through modulation of cancer glycolytic cell metabolism Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-29 Mahrou Vahabi, Annalisa Comandatore, Marika A. Franczak, Ryszard T. Smolenski, Godefridus J. Peters, Luca Morelli, Elisa Giovannetti
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Brain-derived neurotrophic factor: Its role in energy balance and cancer cachexia Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-18 Barış Çerçi, Ayşenur Gök, Aytekin Akyol
Brain-derived neurotrophic factor (BDNF) plays an important role in the development of the central and peripheral nervous system during embryogenesis. In the mature central nervous system, BDNF is required for the maintenance and enhancement of synaptic transmissions and the survival of neurons. Particularly, it is involved in the modulation of neurocircuits that control energy balance through food
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Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-13 Guilherme Pasetto Fadanni, João Batista Calixto
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Recent advances in the treatment of IBD: Targets, mechanisms and related therapies Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-13 Juan Liu, Bin Di, Li-li Xu
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Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms? Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-01 Shaodong Li, Ruizhi Dong, Zhenhua Kang, Hucheng Li, Xueliang Wu, Tian Li
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Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond – A lipids focus Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-07-01 Shikha Rani, Andrew Lai, Soumya Nair, Shayna Sharma, Aase Handberg, Flavio Carrion, Andreas Möller, Carlos Salomon
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Lipid metabolism in regulation of B cell development and autoimmunity Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-30 Xing Ji, Liang Wu, Tony Marion, Yubin Luo
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Targeting the metabolism and immune system in pancreatic ductal adenocarcinoma: Insights and future directions Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-30 Dhana Sekhar Reddy Bandi, Sujith Sarvesh, Batoul Farran, Ganji Purnachandra Nagaraju, Bassel F. El-Rayes
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Growth differentiation factor 11: A new hope for the treatment of cardiovascular diseases Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-30 Yingchun Shao, Yanhong Wang, Jiazhen Xu, Yang Yuan, Dongming Xing
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mTOR in programmed cell death and its therapeutic implications Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-24 Yawen Xie, Xianli Lei, Guoyu Zhao, Ran Guo, Na Cui
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Modulation of IL-33/ST2 signaling as a potential new therapeutic target for cardiovascular diseases Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-22 Punniyakoti Veeraveedu Thanikachalam, Srinivasan Ramamurthy, Poojitha Mallapu, Sudhir Rama Varma, Jayaraj Narayanan, Mohammed AS Abourehab, Prashant Kesharwani
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Exosomal noncoding RNA-mediated spatiotemporal regulation of lipid metabolism: Implications in immune evasion and chronic inflammation Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-06-16 Mangala Hegde, Aviral Kumar, Sosmitha Girisa, Mohammed S. Alqahtani, Mohamed Abbas, Akul Goel, Kam Man Hui, Gautam Sethi, Ajaikumar B. Kunnumakkara
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Acinar cells and the development of pancreatic fibrosis Cytokine Growth Factor Rev. (IF 13.0) Pub Date : 2023-05-26 Jianhong An, Tingting Jiang, Ling Qi, Keping Xie