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Acrylonitrile derivatives: In vitro activity and mechanism of cell death induction against Trypanosoma cruzi and Leishmania amazonensis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-03-06 Carlos J. Bethencourt-Estrella, Samuel Delgado-Hernández, Atteneri López-Arencibia, Desirée San Nicolás-Hernández, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, David Tejedor, Fernando García-Tellado, Jacob Lorenzo-Morales, José E. Piñero
Leishmaniasis and Chagas disease are parasitic infections that affect millions of people worldwide, producing thousands of deaths per year. The current treatments against these pathologies are not totally effective and produce some side effects in the patients. Acrylonitrile derivatives are a group of compounds that have shown activity against these two diseases. In this work, four novels synthetic
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Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-03-02 Estefanía Dibello, Natalia Oddone, Jaime Franco, Tünde-Zita Illyés, Andrea Medeiros, Attila Kiss, Fanni Hőgye, Katalin E. Kövér, László Szilágyi, Marcelo A. Comini
Earlier evidences showed that diglycosyl diselenides are active against the infective stage of African trypanosomes (top hits IC 0.5 and 1.5 μM) but poorly selective (selectivity index <10). Here we extended the study to 33 new seleno-glycoconjugates with the aim to improve potency and selectivity. Three selenoglycosides and three glycosyl selenenylsulfides displayed IC against bloodstream in the sub-μM
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Modified peptides and organic metabolites of cyanobacterial origin with antiplasmodial properties Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-29 Maria Elizbeth Alvarez-Sánchez, Rodrigo Arreola, Saray Quintero-Fabián, Gilberto Pérez-Sánchez
As etiological agents of malaria disease, spp. parasites are responsible for one of the most severe global health problems occurring in tropical regions of the world. This work involved compiling marine cyanobacteria metabolites reported in the scientific literature that exhibit antiplasmodial activity. Out of the 111 compounds mined and 106 tested, two showed antiplasmodial activity at very low concentrations
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Revisiting anthelmintic resistance in sheep flocks from São Paulo State, Brazil Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-28 Cesar C. Bassetto, Ana Cláudia A. Albuquerque, José Gabriel G. Lins, Naiara M. Marinho-Silva, Marianna L.E. Chocobar, Hornblenda J.S. Bello, Mateus O. Mena, Simone C.M. Niciura, Alessandro F.T. Amarante, Ana Carolina S. Chagas
and are the most important gastrointestinal nematodes causing serious losses in sheep production of tropical and subtropical regions. Prophylaxis of gastrointestinal nematode infections is based on anthelmintics use, but their frequent administration selects multiple-resistant parasites. To evaluate how the situation has changed over the last decades, the anthelmintic resistance status of gastrointestinal
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The first report of triple anthelmintic resistance on a French thoroughbred stud farm Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-23 Aurélie Merlin, Nicolas Larcher, José-Carlos Vallé-Casuso
This study assessed the anthelmintic resistance in strongylid nematodes against commonly used anthelmintic (AH) drugs in a French galloping racehorse stud farm from March to December 2023. Faecal egg count reduction tests (FECRTs) were conducted in three different groups of Thoroughbred yearlings (a group of 6 males, a group of 13 females and a group of 8 females and 3 males) following the new World
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Integrated application of transcriptomics and metabolomics provides insight into the mechanism of Eimeria tenella resistance to maduramycin Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-15 Huanzhi Zhao, Hui Dong, Qiping Zhao, Shunhai Zhu, Liushu Jia, Sishi Zhang, Qian Feng, Yu Yu, Jinwen Wang, Bing Huang, Hongyu Han
Avian coccidiosis, caused by parasites, continues to devastate the poultry industry and results in significant economic losses. Ionophore coccidiostats, such as maduramycin and monensin, are widely used for prophylaxis of coccidiosis in poultry. Nevertheless, their efficacy has been challenged by widespread drug resistance. However, the underlying mechanisms have not been revealed. Understanding the
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Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonensis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-09 Juliana Figueiredo Peixoto, Luiz Filipe Gonçalves-Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Léa Cysne Finkelstein, Geovane Dias-Lopes, Beatriz Ferreira de Carvalho Patricio, Carolina Guimarães de Souza Lima, Helvécio Vinícius Antunes Rocha, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Bernardo Acácio Santini Pereira, Carlos Roberto Alves
Leishmaniasis is a widespread disease caused by spp., affecting millions of people around the world. For decades, its treatment has been based on pentavalent antimonials, which notoriously cause toxic side effects in patients. In this study, epoxy-α-lapachone incorporated into an oil-in-water-type microemulsion (ELAP-ME) and meglumine antimoniate (MA) were assayed in monotherapy and in combination
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Chicory (Cichorium intybus) reduces cyathostomin egg excretion and larval development in grazing horses Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-09 Joshua Malsa, Leslie Boudesocque-Delaye, Laurence Wimel, Juliette Auclair-Ronzaud, Bertrand Dumont, Núria Mach, Fabrice Reigner, Fabrice Guégnard, Angélique Chereau, Delphine Serreau, Isabelle Théry-Koné, Guillaume Sallé, Géraldine Fleurance
Cyathostomins are the most prevalent parasitic nematodes of grazing horses. They are responsible for colic and diarrhea in their hosts. After several decades of exposure to synthetic anthelmintics, they have evolved to become resistant to most compounds. In addition, the drug-associated environmental side-effects question their use in the field. Alternative control strategies, like bioactive forages
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Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-02-06 Alistair Antonopoulos, Claude L. Charvet, Kirsty Maitland, Stephen R. Doyle, Cédric Neveu, Roz Laing
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Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-01-23 Harrison T. Shanley, Aya C. Taki, Nghi Nguyen, Tao Wang, Joseph J. Byrne, Ching-Seng Ang, Michael G. Leeming, Shuai Nie, Nicholas Williamson, Yuanting Zheng, Neil D. Young, Pasi K. Korhonen, Andreas Hofmann, Bill C.H. Chang, Tim N.C. Wells, Cécile Häberli, Jennifer Keiser, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
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Herbal-based compounds: A review on treatments of cryptosporidiosis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-01-14 Fatemeh Namazi, Seyed Mostafa Razavi
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Benzimidazole F167Y polymorphism in the canine hookworm, Ancylostoma caninum: Widespread geographic, seasonal, age, and breed distribution in United States and Canada dogs Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2024-01-12 Christian M. Leutenegger, Michelle D. Evason, Jennifer L. Willcox, Haresh Rochani, Holly L. Richmond, Cathy Meeks, Cecilia E. Lozoya, Jeffrey Tereski, Samantha Loo, Kelly Mitchell, Jan Andrews, Christian Savard
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Phenotypic and genotypic characterization of acaricide resistance in Rhipicephalus microplus field isolates from South Africa and Brazil Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-12-27 Dieter J.A. Heylen, Michel Labuschagne, Christina Meiring, Luther van der Mescht, Guilherme Klafke, Livio Martins Costa Junior, Tom Strydom, Jeanette Wentzel, Caryn Shacklock, Lénaig Halos, Francois Maree, Josephus Fourie, Maxime Madder, Alec Evans
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A national survey of anthelmintic resistance in ascarid and strongylid nematodes in Australian Thoroughbred horses Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-29 Ghazanfar Abbas, Abdul Ghafar, Emma McConnell, Anne Beasley, Jenni Bauquier, Edwina J.A. Wilkes, Charles El-Hage, Peter Carrigan, Lucy Cudmore, John Hurley, Charles G. Gauci, Ian Beveridge, Elysia Ling, Caroline Jacobson, Mark A. Stevenson, Martin K. Nielsen, Kristopher J. Hughes, Abdul Jabbar
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Efficacy of flukicides against Fasciola hepatica and first report of triclabendazole resistance on German sheep farms Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-21 Alexandra Kahl, Georg von Samson-Himmelstjerna, Christina Helm, Jane Hodgkinson, Diana Williams, Wiebke Weiher, Werner Terhalle, Stephan Steuber, Martin Ganter, Jürgen Krücken
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Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-21 Elena Deligianni, Elisabetta Pizzi, Ioanna Kavelaki, Inga Siden-Kiamos, Filippo Umberto Sapienza, Rossella Fioravanti, Stefania Garzoli, Tomasino Pace, Marta Ponzi, Rino Ragno, Chiara Currà
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Effects of the G-quadruplex-binding drugs quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-24 Holly M. Craven, Guilherme Nettesheim, Pietro Cicuta, Andrew M. Blagborough, Catherine J. Merrick
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Functional characterization of three G protein-coupled acetylcholine receptors in parasitic nematode Trichinella spiralis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-24 Cáinà Nìng, Aurélie Heckmann, Lourdes Mateos-Hernández, Grégory Karadjian, Ladislav Šimo
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Evaluation of topotecan and 10-hydroxycamptothecin on Toxoplasma gondii: Implications on baseline DNA damage and repair efficiency Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-24 Constanza Cristaldi, Ana M. Saldarriaga Cartagena, Agustina Ganuza, William J. Sullivan, Sergio O. Angel, Laura Vanagas
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Demonstration of reduced efficacy against cyathostomins without change in species composition after pyrantel embonate treatment in Swedish equine establishments Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-11-14 Ylva Hedberg Alm, Peter Halvarsson, Frida Martin, Eva Osterman-Lind, Vendela Törngren, Eva Tydén
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Erratum to ‘Uncovering the antimalarial potential of toad venoms through a bioassay-guided fractionation process’ [International Journal for Parasitology: Drugs and Drug Resistance 20 (2022) 97-107] Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-10-11 Mathilde Wells, Mathieu Fossépré, Stéphanie Hambye, Mathieu Surin, Bertrand Blankert
Abstract not available
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Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-10-10 Pieter C. Steketee, Edith Paxton, Michael P. Barrett, Michael C. Pearce, Timothy K. Connelley, Liam J. Morrison
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Trichuris muris egg-hatching assay for anthelminthic drug discovery and characterization Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-10-09 Anastasia Schärer, Stefan Biendl, Jennifer Keiser
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Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-09-22 Christopher JS. Hart, Andrew G. Riches, Snigdha Tiash, Rebecca Abraham, Keely Fayd’Herbe, Ellis Joch, Bilal Zulfiqar, Melissa L. Sykes, Vicky M. Avery, Jan Šlapeta, Sam Abraham, John H. Ryan, Tina S. Skinner-Adams
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Suramin action in African trypanosomes involves a RuvB-like DNA helicase Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-09-19 Anna Albisetti, Silvan Hälg, Martin Zoltner, Pascal Mäser, Natalie Wiedemar
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Increased copy number of the target gene squalene monooxygenase as the main resistance mechanism to terbinafine in Leishmania infantum Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-09-09 Jade-Éva Potvin, Fereshteh Fani, Marine Queffeulou, Élodie Gazanion, Philippe Leprohon, Marc Ouellette
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Identification of new drug candidates against Trichomonas gallinae using high-throughput screening Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-08-05 Shengfan Jing, Qingxun Zhang, Yi Li, Han Chang, Chen Xiang, Shuyi Han, Guohui Yuan, Jinghui Fan, Hongxuan He
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Therapeutic advantages of the combined use of closantel and moxidectin in lambs parasitized with resistant gastrointestinal nematodes Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-08-02 Gonzalo Suárez, Daniel Castells, Fernanda Imperiale, Pietro Fagiolino, Candela Canton, Carlos Lanusse, Luis Alvarez
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Ascaridia galli - An old problem that requires new solutions Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-07-24 Johan Höglund, Gürbüz Daş, Behdad Tarbiat, Peter Geldhof, Désirée S. Jansson, Matthias Gauly
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Multiple anthelmintic drug resistant Ancylostoma caninum in foxhounds Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-07-20 Jenna D. Balk, Nathan D. Mitchell, Jake Hughes, Priscila Soto Nauto, Joseph Rossi, Roger Ramirez-Barrios
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Droplet digital PCR as a tool to detect resistant isolates of Dirofilaria immitis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-07-23 Sohini Kumar, Roger K. Prichard, Thavy Long
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Apparent treatment failure of praziquantel and pyrantel pamoate against anoplocephalid tapeworms Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-06-19 M.K. Nielsen
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Development of a three-colour digital PCR for early and quantitative detection of benzimidazole resistance-associated single nucleotide polymorphisms in Haemonchus contortus Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-06-18 Barbara Hinney, Sandra Wiedermann, Antonio Bosco, Laura Rinaldi, Martin Hofer, Anja Joachim, Jürgen Krücken, Ralf Steinborn
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Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-06-08 Haddijatou Mbye, Fatoumata Bojang, Fatou Kene Jaiteh, Aminata Jawara, Bekai Njie, Simon Correa, Umberto D'Alessandro, Alfred Amambua-Ngwa
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Identification and characterization of novel marine oxasqualenoid yucatecone against Naegleria fowleri Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-05-29 Iñigo Arberas-Jiménez, Francisco Cen-Pacheco, Javier Chao-Pellicer, Ines Sifaoui, Aitor Rizo-Liendo, Ezequiel Q. Morales, Antonio H. Daranas, Ana R. Díaz-Marrero, José E. Piñero, José J. Fernández, Jacob Lorenzo-Morales
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Genomic analysis of Indian isolates of Plasmodium falciparum: Implications for drug resistance and virulence factors Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-05-29 Deepak Choubey, Bhagyashree Deshmukh, Anjani Gopal Rao, Abhishek Kanyal, Amiya Kumar Hati, Somenath Roy, Krishanpal Karmodiya
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In vitro activity and mechanism of cell death induction of cyanomethyl vinyl ethers derivatives against Trypanosoma cruzi Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-05-31 Carlos J. Bethencourt-Estrella, Samuel Delgado-Hernández, Atteneri López-Arencibia, Desirée San Nicolás-Hernández, David Tejedor, Fernando García-Tellado, Jacob Lorenzo-Morales, José E. Piñero
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Forward genetic analysis of monensin and diclazuril resistance in Eimeria tenella Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-05-24 Hongtao Zhang, Lei Zhang, Ganglin Ren, Hongbin Si, Xingju Song, Xianyong Liu, Xun Suo, Dandan Hu
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Reflecting on the past and fast forwarding to present day anthelmintic resistant Ancylostoma caninum–A critical issue we neglected to forecast Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-05-10 Antoinette E. Marsh, Jeffrey Lakritz
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Integration of ITS-2 rDNA nemabiome metabarcoding with Fecal Egg Count Reduction Testing (FECRT) reveals ivermectin resistance in multiple gastrointestinal nematode species, including hypobiotic Ostertagia ostertagi, in western Canadian beef cattle Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-04-22 Eranga L. De Seram, Fabienne D. Uehlinger, Camila de Queiroz, Elizabeth M. Redman, John R. Campbell, Drue Nooyen, Arianna Morisetti, Colleen M. Pollock, Samantha Ekanayake, Gregory B. Penner, John S. Gilleard
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The Haemonchus contortus LGC-39 subunit is a novel subtype of an acetylcholine-gated chloride channel Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-04-06 Sarah Habibi, Kristen Nazareth, Jennifer Nichols, Sierra Varley, Sean G. Forrester
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Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-24 Qiao Su, Louise Baker, Samantha Emery, Balu Balan, Brendan Ansell, Swapnil Tichkule, Ivo Mueller, Staffan G. Svärd, Aaron Jex
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Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-15 Vanessa M. Howieson, Joy Zeng, Joachim Kloehn, Christina Spry, Chiara Marchetti, Matteo Lunghi, Emmanuel Varesio, Andrew Soper, Anthony G. Coyne, Chris Abell, Giel G. van Dooren, Kevin J. Saliba
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Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-14 Christian M. Leutenegger, Cecilia E. Lozoya, Jeffrey Tereski, Christian Savard, Jennifer Ogeer, Rene Lallier
Background Anthelmintic resistance to benzimidazole has been detected in the canine hookworm, Ancylostoma caninum. Benzimidazole resistance is believed to have developed originally in greyhounds, but has also been detected in non-greyhound pet dogs. The aim of this study was to validate a probe-based allele-specific real-time PCR tests for the F167Y polymorphism on the β-tubulin isotype-1 gene and
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Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-05 Kotaro Takano, Lachlan de Hayr, Scott Carver, Robert J. Harvey, Kate E. Mounsey
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Investigation of the mechanism of action of mefloquine and derivatives against the parasite Echinococcus multilocularis Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-09 Roman Memedovski, Matías Preza, Joachim Müller, Tobias Kämpfer, Reto Rufener, Marcus Vinicius Nora de Souza, Emerson Teixeira da Silva, Gabriel Fernandes de Andrade, Sophie Braga, Anne-Christine Uldry, Natasha Buchs, Manfred Heller, Britta Lundström-Stadelmann
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The first report of macrocyclic lactone resistant cyathostomins in the UK Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-03-07 K.E. Bull, K.J. Allen, J.E. Hodgkinson, L.E. Peachey
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OBITUARY- Ian Fairweather Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-02-14 Mark W. Robinson, Bob Hanna, Philip Skuce, Gerry Brennan
Abstract not available
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The presence and relative frequency detection of the levamisole-resistance-associated S168T substitution in hco-acr-8 in Haemonchus contortus Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-02-08 Paulius Baltrušis, Peter Halvarsson, Claude L. Charvet, Johan Höglund
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Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-02-04 Jiao Mo, Hongfei Si, Siyang Liu, Qingyuan Zeng, Minghao Cai, Zhendi Liu, Jiyu Zhang, Jingjing Fang, Jili Zhang
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Molecular characterization and analysis of drug resistance-associated protein enolase 2 of Eimeria tenella Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-02-03 Yu Yu, Wenhao Huang, Qingjie Wang, Hui Dong, Qiping Zhao, Shunhai Zhu, Bing Huang, Hongyu Han
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Addressing the oxamniquine in vitro-in vivo paradox to facilitate a new generation of anti-schistosome treatments Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-01-30 Katalin Toth, Sevan Alwan, Susan Khan, Stanton F. McHardy, Philip T. LoVerde, Michael D. Cameron
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Ring stage dormancy of Plasmodium falciparum tolerant to artemisinin and its analogues – A genetically regulated “Sleeping Beauty” Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2023-01-16 Saranya Auparakkitanon, Prapon Wilairat
The appearance in 2008 in western Cambodia of Plasmodium falciparum tolerant to artemisinin, defined by longer parasite clearance time following drug administration and in vitro by a slightly higher survival rate of the ring stage after a 3-h treatment with 700 nM artemisinin (or analogues, collectively termed ART), has raised concerns of the possible loss of this frontline antimalarial [used in the
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Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-12-21 Christina S. Saghaug, Astrid L. Gamlem, Kirsti B. Hauge, Juha Vahokoski, Christian Klotz, Toni Aebischer, Nina Langeland, Kurt Hanevik
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Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-12-13 Stephanie L. Macdonald, Ghazanfar Abbas, Abdul Ghafar, Charles G. Gauci, Jenni Bauquier, Charles El-Hage, Brett Tennent-Brown, Edwina J.A. Wilkes, Anne Beasley, Caroline Jacobson, Lucy Cudmore, Peter Carrigan, John Hurley, Ian Beveridge, Kristopher J. Hughes, Martin K. Nielsen, Abdul Jabbar
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Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-12-08 Joachim Müller, Carling Schlange, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Richard K. Haynes, Andrew Hemphill
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Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-12-08 Agriana Rosmalina Hidayati, Melinda, Hilkatul Ilmi, Takaya Sakura, Miako Sakaguchi, Junko Ohmori, Endah Dwi Hartuti, Lidya Tumewu, Daniel Ken Inaoka, Mulyadi Tanjung, Eri Yoshida, Fuyuki Tokumasu, Kiyoshi Kita, Mihoko Mori, Kazuyuki Dobashi, Tomoyoshi Nozaki, Din Syafruddin, Achmad Fuad Hafid, Danang Waluyo, Aty Widyawaruyanti
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Poor adherence is a major barrier to the proper treatment of cutaneous leishmaniasis: A case-control field assessment in Iran Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-12-05 Mehdi Bamorovat, Iraj Sharifi, Setareh Agha Kuchak Afshari, Ali Karamoozian, Amirhossein Tahmouresi, Amireh Heshmatkhah, Ehsan Salarkia, Ahmad Khosravi, Maryam Hakimi Parizi, Maryam Barghi
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Thiophene derivatives activity against the protozoan parasite Leishmania infantum Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-11-25 Sophia Bigot, Philippe Leprohon, Abimael Vasquez, Rohit Bhadoria, Rachid Skouta, Marc Ouellette
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Exploration of the sensitivity to macrocyclic lactones in the canine heartworm (Dirofilaria immitis) in Australia using phenotypic and genotypic approaches Int. J. Parasitol. Drugs Drug Resist. (IF 4.0) Pub Date : 2022-11-15 Rosemonde Isabella Power, Jan Šlapeta