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Nutrition and Public Health in Georgia: Reviewing the current status and inspiring improvements: A joint event of the Georgian Nutrition Society, The Nutrition Society of the UK and Ireland and the Sabri Ülker Foundation, October 2023 Briti. J. Nutr. (IF 3.6) Pub Date : 2024-03-08 Julian D Stowell, John C Mathers, Manana Stanley, F Nur Baran Aksakal, Avril Aslett-Bentley, Diána Bánáti, Eka Bobokhidze, Özlem Üliç Çatar, Özge Dinç, Rusudan Gvamichava, Begüm Mutus, Caroline Saunders, Oliver Shannon, Ihab Tewfik
Georgia lies to the north east of Türkiye, having a western border on the Black Sea. With a population of some 3.73 million, Georgia has a tradition of gastronomic excellence dating back millennia. However, changing lifestyles and external influences have, as elsewhere, led to problems of suboptimal nutrition, and lifestyle related diseases and disorders prevail. There is considerable scope for improving
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Effects of beef fat enriched with trans vaccenic acid and cis9, trans11-conjugated linoleic acid on glucose homeostasis and hepatic lipid accumulation in high-fat diet induced obese mice Briti. J. Nutr. (IF 3.6) Pub Date : 2024-03-05 Yanqing Xu, Ming-Fo Hsu, Fawaz Haj, Payam Vahmani
Trans vaccenic acid (TVA, trans11-18:1) and cis9, trans11-conjugated linoleic acid (also known as rumenic acid; RA) have received widespread attention as potentially beneficial trans fatty acids due to their putative health benefits, including anti-diabetic properties. The objective of this study was to determine the effects of beef fat naturally enriched with TVA and RA on parameters related to glucose
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Educational Intervention Based on the Extended Parallel Process Model Improves Adherence to Diabetic Diet and Glycemic Control Indices: a Randomized, Double-blind, Controlled, Factorial Field Trial Briti. J. Nutr. (IF 3.6) Pub Date : 2024-03-01 Tayebe Dehghan, Mohammad Ali Mohsenpour, Masoud Karimi, Manoosh Mehrabi, Morteza Zare, Marzieh Akbarzadeh, Atefeh Kohansal, Fatemeh Fathi, Zahra Sohrabi
Nutritional education is pivotal in the medical nutritional therapy of type 2 diabetes Mellitus (T2DM). The extended parallel process model (EPPM) is a health education method for inducing desirable health behaviors. The present study aimed to investigate the effect of nutritional education based on the EPPM in T2DM patients on knowledge, attitude, practice (KAP), anthropometric indices, glycemic factors
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Postprandial plasma amino acid and appetite responses with ingestion of a novel salmon-derived protein peptide in healthy young adults Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-29 Sophie Prosser, Mia Fava, Lucy M. Rogers, Bjørn Liaset, Leigh Breen
This study assessed postprandial plasma aminoacidemia, glycemia, insulinemia and appetite responses to ingestion of a novel salmon-derived protein peptide (Salmon PP) compared with milk protein isolate (Milk PI). In a randomised, participant-blind crossover design, eleven healthy adults (M = 5, F = 6; mean ± sd age: 22 ± 3 years; BMI: 24 ± 3 kg/m2) ingested 0·3 g/kg/body mass of Salmon PP or Milk PI
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Glycine supplementation can partially restore oxidative stress associated glutathione deficiency in ageing cats Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-29 Avika Ruparell, Janet E. Alexander, Ryan Eyre, Laura Carvell-Miller, Y. Becca Leung, Samantha J. M. Evans, Lucy J. Holcombe, Martina Heer, Phillip Watson
Intracellular levels of glutathione, the major mammalian antioxidant, are reported to decline with age in several species. To understand whether ageing affects circulating glutathione levels in cats, blood was sampled from two age groups, < 3 years and > 9 years. Further, to determine whether dietary supplementation with glutathione precursor glycine (GLY) affects glutathione concentrations in senior
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EGG WHITE HYDROLYSATE PROTECTS WHITE ADIPOSE TISSUE AGAINST METABOLIC INSULT IN DOCA-SALT RATS Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-27 Camila Rodrigues Moro, Edina da Luz Abreu, Samia Hassan Husein Kanaan, Antonio Márquez, Jose Antonio Uranga-Ocio, Luciana Venturini Rossoni, Dalton Valentim Vassallo, Marta Miguel-Castro, Giulia Alessandra Wiggers
The purpose of this study was to investigate the effect of an egg white hydrolysate (EWH) to protect white adipose tissue damage from cardiometabolic changes induced by severe hypertension. Male Wistar rats were uninephrectomized and divided: SHAM (weekly subcutaneous vehicle [mineral oil + propylene glycol, 1:1]), SHAM+EWH (subcutaneous vehicle plus EWH via gavage, 1g/kg/day), DOCA (deoxycorticosterone
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Does sweetness exposure drive ‘sweet tooth’? Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-26 David J. Mela, Davide Risso
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Dietary intake of dicarbonyl compounds and changes in body weight over time in a large cohort of European adults Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-22 Charlotte Debras, Reynalda Cordova, Ana-Lucia Mayén, Kim Maasen, Viktoria Knaze, Simone J. P. M. Eussen, Casper G. Schalkwijk, Inge Huybrechts, Anne Tjønneland, Jytte Halkjær, Verena Katzke, Rashmita Bajracharya, Matthias B. Schulze, Giovanna Masala, Valeria Pala, Fabrizio Pasanisi, Alessandra Macciotta, Dafina Petrova, Jazmin Castañeda, Carmen Santiuste, Pilar Amiano, Conchi Moreno-Iribas, Yan Borné
Dicarbonyl compounds are highly reactive precursors of advanced glycation end products (AGE), produced endogenously, present in certain foods and formed during food processing. AGE contribute to the development of adverse metabolic outcomes, but health effects of dietary dicarbonyls are largely unexplored. We investigated associations between three dietary dicarbonyl compounds, methylglyoxal (MGO)
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Interplay between polygenic variants related immune response and lifestyle factors mitigate the chances of stroke in a genome-wide association study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-20 Sunmin Park
We aimed to investigate the intricate interplay between genetic predisposition and lifestyle factors on stroke. We conducted a comprehensive genome-wide association study to identify the genetic variants linked to stroke in the participants who experienced a stroke event (cases; n 672) and those with no stroke history (non-stroke; n 58 029) in a large hospital-based cohort. Using generalised multifactor
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Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-16 Marianne Bråtveit, Anthea Van Parys, Thomas Olsen, Elin Strand, Ingvild Marienborg, Johnny Laupsa-Borge, Teresa Risan Haugsgjerd, Adrian McCann, Indu Dhar, Per Magne Ueland, Jutta Dierkes, Simon Nitter Dankel, Ottar Kjell Nygård, Vegard Lysne
Elevated plasma concentrations of several one-carbon metabolites are associated with increased CVD risk. Both diet-induced regulation and dietary content of one-carbon metabolites can influence circulating concentrations of these markers. We cross-sectionally analysed 1928 patients with suspected stable angina pectoris (geometric mean age 61), representing elevated CVD risk, to assess associations
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Association of green tea consumption with prediabetes, diabetes and markers of glucose metabolism in rural Vietnam: a cross-sectional study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-16 Ami Fukunaga, Masamine Jimba, Thuy Thi Phuong Pham, Chau Que Nguyen, Dong Van Hoang, Tien Vu Phan, Aki Yazawa, Danh Cong Phan, Masahiko Hachiya, Huy Xuan Le, Hung Thai Do, Tetsuya Mizoue, Yosuke Inoue
The literature on green tea consumption and glucose metabolism has reported conflicting findings. This cross-sectional study examined the association of green tea consumption with abnormal glucose metabolism among 3000 rural residents aged 40–60 years in Khánh Hòa province in Vietnam. Multinomial logistic regression analysis was conducted to examine the association of green tea consumption (0, < 200
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Adherence to Mediterranean diet is inversely associated with depressive symptoms in older women: findings from the NutBrain Study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-16 Silvia Conti, Elena Perdixi, Sara Bernini, Nithiya Jesuthasan, Marco Severgnini, Federica Prinelli
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Non-linear relationship between the body roundness index and metabolic syndrome: data from National Health and Nutrition Examination Survey (NHANES) 1999–2018 Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-15 Zhenhan Li, Chunhua Fan, Jun Huang, Zhongpei Chen, Xiaoxia Yu, Jun Qian
Obesity is an important characteristic manifestation of metabolic syndrome (MetS), and body roundness index (BRI) is one of the anthropometric indicators associated with obesity. However, studies on the relationship between BRI and MetS risk are limited. We aimed to explore the relationship between baseline BRI and MetS in the USA population. Our study used data from the National Health and Nutrition
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Association of the short-chain fatty acid levels and dietary quality with type 2 diabetes: a case–control study based on Henan Rural Cohort Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-12 Jia Li, Yuqian Li, Shuhua Zhang, Chongjian Wang, Zhenxing Mao, Wenqian Huo, Tianyu Yang, Yan Li, Wenguo Xing, Linlin Li
Evidence of the relationship between fecal short-chain fatty acids (SCFA) levels, dietary quality and type 2 diabetes mellitus (T2DM) in rural populations is limited. Here, we aimed to investigate the association between fecal SCFA levels and T2DM and the combined effects of dietar quality on T2DM in rural China. In total, 100 adults were included in the case–control study. Dietary quality was assessed
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Dietary factors and the risk of atopic dermatitis: a Mendelian randomisation study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-12 Yuhui Che, Jinyao Yuan, Qian Wang, Mengsong Liu, Dadong Tang, Mulan Chen, Xinyu Xiao, Yaobin Pang, Siyan Chen, Wen Han, Zhiyong Xiao, Jinhao Zeng, Jing Guo
Previous studies have revealed an association between dietary factors and atopic dermatitis (AD). To explore whether there was a causal relationship between diet and AD, we performed Mendelian randomisation (MR) analysis. The dataset of twenty-one dietary factors was obtained from UK Biobank. The dataset for AD was obtained from the publicly available FinnGen consortium. The main research method was
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The Mini Nutritional Assessment combined with body fat for detecting the risk of sarcopenia and sarcopenic obesity in metabolic syndrome Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-05 Chi-Hua Yen, Yi-Wen Lee, Wei-Jung Chang, Ping-Ting Lin
Malnutrition is a key factor in metabolic syndrome (MS) and sarcopenia, assessing the nutritional status of these patients is a pressing issue. The purpose of this study was to clarify sarcopenia and sarcopenic obesity in patients with MS based on nutritional status. This was a case–control study between MS/non-MS. Body composition was measured by dual-energy X-ray absorptiometry. Muscle function was
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Nature of the evidence base and approaches to guide nutrition interventions for individuals: a position paper from the Academy of Nutrition Sciences Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-02 Mary Hickson, Constantina Papoutsakis, Angela M Madden, Mary Anne Smith, Kevin Whelan
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The association between dietary patterns and disease severity in patients with ulcerative colitis Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-02 Mohammad Reza Amini, Zeinab Khademi, Marieh Salavatizadeh, Niloufar Rasaei, Nasser Ebrahimi-Daryani, Ahmad Esmaillzadeh, Azita Hekmatdoost
Ulcerative colitis (UC) is a chronic inflammatory disease involving the colon and rectum. One of the most modifiable environmental factors affecting UC severity is the patient’s dietary pattern. Although the role of dietary patterns on UC aetiology has been investigated previously, its relationship with disease severity has not yet been elucidated. This study examined the association between UC patients’
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H2OAthletes study protocol: effects of hydration changes on neuromuscular function in athletes Briti. J. Nutr. (IF 3.6) Pub Date : 2024-02-01 Rúben Francisco, Filipe Jesus, Catarina L. Nunes, Paulo Santos, Marta Alvim, Francesco Campa, Dale A. Schoeller, Henry Lukaski, Goncalo V. Mendonca, Luís Fernando Cordeiro Bettencourt Sardinha, Analiza Mónica Lopes de Almeida Silva
We aim to understand the effects of hydration changes on athletes’ neuromuscular performance, on body water compartments, fat-free mass hydration and hydration biomarkers and to test the effects of the intervention on the response of acute dehydration in the hydration indexes. The H2OAthletes study (clinicaltrials.gov ID: NCT05380089) is a randomised controlled trial in thirty-eight national/international
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High starch intake favours body weight control in neutered and spayed cats living in homes fed ad libitum Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-31 Camila Goloni, Letícia G. Pacheco, Letícia W. Luis, Stephanie S. Theodoro, Lucas B. Scarpim, Daniela Dalpubel, Meire Gallo Rosenburg, Isabelle C. Jeusette, Celina Torre, Gener T. Pereira, Aulus C. Carciofi
Different starch-to-protein ratios were compared among neutered and spayed domiciled cats. Male and female obese and non-obese cats were fed kibble diets ad libitum for 4 months high in starch (HS (38 % crude protein (CP)): starch 32 %, protein 38 %; DM basis) or high in protein (HP (55 % CP): starch 19 %, protein 55 %) but similar in energy and fat in a crossover design. Physical activity was evaluated
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Salivary iodide status as a measure of whole body iodine homoeostasis? Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-30 Eatedal Eenizan Alsaeedi, Peter Rose, Simon J. M. Welham
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Spicy food consumption reduces the risk of ischaemic stroke: a prospective study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-30 Jiale Li, Changping Xie, Jian Lan, Jinxue Tan, Xiaoping Tan, Ningyu Chen, Liuping Wei, Jiajia Liang, Rong Pan, Tingping Zhu, Pei Pei, Dianjianyi Sun, Li Su, Lifang Zhou
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Effects of physical form of β-lactoglobulin and calcium ingestion on GLP-1 secretion, gastric emptying and energy intake in humans: a randomised crossover trial Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-30 Jonathan D. Watkins, Harry A. Smith, Aaron Hengist, Søren B. Nielsen, Ulla Ramer Mikkelsen, John Saunders, Francoise Koumanov, James A. Betts, Javier T. Gonzalez
The aim of this study was to assess whether adding Ca2+ to aggregate or native forms of β-lactoglobulin alters gut hormone secretion, gastric emptying rates and energy intake in healthy men and women. Fifteen healthy adults (mean ± sd: 9M/6F, age: 24 ± 5 years) completed four trials in a randomised, double-blind, crossover design. Participants consumed test drinks consisting of 30 g of β-lactoglobulin
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Association between n-3 PUFA and lung function: results from the NHANES 2007–2012 and Mendelian randomisation study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-26 Jingli Li, Jian Sun, Lingjing Liu, Chunyi Zhang, Zixiang Liu
This study aimed to investigate the association between n-3 PUFA and lung function. First, a cross-sectional study was conducted based on the National Health and Nutrition Examination Survey (NHANES) 2007–2012 data. n-3 PUFA intake was obtained from 24-h dietary recalls. A multivariable linear regression model was used to assess the observational associations of n-3 PUFA intake with lung function.
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Delivery of a telehealth supported home exercise program with dietary advice to increase plant-based protein intake in people with non-alcoholic fatty liver disease: a 12-week randomised controlled feasibility trial Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-25 Christine L. Freer, Elena S. George, Sze-Yen Tan, Gavin Abbott, Robin M. Daly
This study evaluated the feasibility and safety of a telehealth delivered exercise plus plant-based protein diet in adults with non-alcoholic fatty liver disease (NAFLD). This was a 12-week, randomised controlled feasibility trial including twenty-eight adults aged > 45 years with NAFLD randomised to a home muscle strengthening program (3 d/week) with increased protein intake (target ∼1·2–1·5 g/kg/d)
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Comparison of international height and BMI-for-age growth references and their correlation with adiposity in Brazilian schoolchildren Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-23 Mariane Helen de Oliveira, Roberto Fernandes da Costa, Mauro Fisberg, Luiz Fernando Martins Kruel, Wolney Lisboa Conde
This study verified the diagnostic accuracy of the nutritional status classified by the international height and BMI references of the World Health Organization (WHO) (WHO/2007), International Obesity Task Force (IOTF/2012) and MULT (2023). The data pool was composed by 22 737 subjects aged five to 16 years from the Santos and Porto Alegre surveys. A correlation matrix between the z-scores of the BMI
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Association of disaster-related damage with inflammatory diet among older survivors of the Great East Japan Earthquake and Tsunami Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-23 Aki Yazawa, Hiroyuki Hikichi, Koichiro Shiba, Sakurako Shiba Okuzono, Katsunori Kondo, Satoshi Sasaki, Ichiro Kawachi
Traumatic experiences from disasters have enduring effects on health, both directly and indirectly by influencing health behaviours. Among potential pathways, the impact of disaster-related trauma on dietary patterns has been understudied. This study investigated the relationship between disaster-related trauma and dietary inflammatory index (DII®), and how these relationships differed by gender and
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Plasma homocysteine, folate and vitamin B12 compared between rural Gambian and UK adults Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Sophie E. Moore, M. Azam Mansoor, Christopher J. Bates, Andrew M. Prentice
The disease risk indicator plasma total homocysteine (tHcy) is influenced by genetic and environmental factors, including folate and vitamin B12 status. Little is known about the determinants of tHcy in rural West Africa. We explored the hypothesis that tHcy in rural Gambian adults might vary between the sexes and physiological groups, an/r with folate and vitamin B12 status. Comparisons were made
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In vitro studies of the digestion of caprine whey proteins by human gastric and duodenal juice and the effects on selected microorganisms Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Hilde Almaas, Halvor Holm, Thor Langsrud, Ragnar Flengsrud, Gerd E. Vegarud
The in vitro digestion of caprine whey proteins was investigated by a two-step degradation assay, using human gastric juice (HGJ) at pH 2·5 and human duodenal juice (HDJ) at pH 7·5. Different protein and peptide profiles were observed after the first (HGJ) and second (HDJ) enzymatic degradation. The minor whey proteins serum albumin, lactoferrin and Ig were rapidly degraded by HGJ, while α-lactalbumin
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Diet and physical activity profiles in French preadolescents Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Carine Platat, Anne-Elisabeth Perrin, Mohamed Oujaa, Aline Wagner, Marie-Christine Haan, Jean-Louis Schlienger, Chantal Simon
Dietary patterns have been identified in adults, but less is known about children and adolescents. For the first time, we have investigated lifestyle patterns combining diet and physical activity in 12-year-old French preadolescents and examined their association with sociodemographic factors. Physical activity, sedentary activities and dietary habits were assessed by questionnaires given to 2724 students
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Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 S. Matthijs Boekholdt, Marijn C. Meuwese, Nicholas E. Day, Robert Luben, Ailsa Welch, Nicholas J. Wareham, Kay-Tee Khaw
High plasma concentrations of ascorbic acid, a marker of fruit and vegetable intake, are associated with low risk of coronary artery disease. Whether this relationship is explained by a reduction in systemic inflammation is unclear. We investigated the relationship between ascorbic acid plasma concentration and coronary artery disease risk, and in addition whether this relationship depended on classical
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Dietary branched-chain amino acid valine, isoleucine and leucine requirements of fingerling Indian major carp, Cirrhinus mrigala (Hamilton) Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Imtiaz Ahmed, Mukhtar A. Khan
Three 8-week growth experiments were conducted to quantify the requirements of the fingerling Cirrhinus mrigala for the dietary branched-chain amino acids valine (experiment 1), isoleucine (experiment 2) and leucine (experiment 3). Six isonitrogenous (400/g) and isoenergetic (17·90k/) test diets were formulated with a gradation of 2·5/g for each test amino acid, valine (7·5–20/g), isoleucine (5·0–17·5/g)
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Maternal protein restriction and fetal growth: lack of evidence of a role for homocysteine in fetal programming Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Simon C. Langley-Evans, Christina Lilley, Sarah McMullen
The disease-programming effects of a maternal low-protein (MLP) diet in rat pregnancy have been suggested to be attributable of hyperhomocysteinaemia. The aim of the present study was to determine whether MLP feeding impacted upon maternal and day 20 fetal homocysteine concentrations, with ensuing effects upon oxidan/ntioxidant status. Sixty-four pregnant rats were fed either MLP diet or control diet
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Butyrate production from oligofructose fermentation by the human faecal flora: what is the contribution of extracellular acetate and lactate? Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Douglas J. Morrison, William G. Mackay, Christine A. Edwards, Tom Preston, Brian Dodson, Lawrence T. Weaver
Butyrate is an important substrate for maintenance of colonic health and oligofructose fermentation by human faecal bacteria can increase butyrate production in vitro. However, oligofructose appears to be fermented by mainly acetate and lactate-producing bacteria rather than butyrate-producing bacteria. Isotope labelling studies using [U-13C6]glucose were used to show that 13C2 and 13C4 were the major
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Dietary soya protein intake and exercise training have an additive effect on skeletal muscle fatty acid oxidation enzyme activities and mRNA levels in rats Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Masashi Morifuji, Chiaki Sanbongi, Katsumi Sugiura
Exercise training and regular physical activity increase oxidation of fat. Enhanced oxidation of fat is important for preventing lifestyle diseases such as hypertension and obesity. The aim of the present study in rats was to determine whether intake of dietary soya protein and exercise training have an additive effect on the activity and mRNA expression of enzymes involved in skeletal muscle fatty
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Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50–65 years consuming their habitual diets Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Graham C. Burdge, Jonathan Powell, Philip C. Calder
The aim of the study was to determine the effect of consuming meals with different fatty acid compositions on the postprandial changes over 6h in plasma triacylglycerol, NEFA, total cholesterol, glucose and insulin concentrations in middle-aged men and women. Men (n 11; 58 (5) years) and women (n 11; 56 (4) years) consumed four test meals with a similar macronutrient energy content in random order:
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Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Akiko Tamura, Megumi Nishimukai, Norihiro Shigematsu, Hiroshi Hara
Equol, a derivative of daidzein produced by enterobacteria, has greater activity as a phyto-oestrogen compared with daidzein. Difructose anhydride III (DFAIII) is a newly manufactured non-digestible disaccharide with unique fermentation properties. The present study evaluated the prebiotic effects of DFAIII on equol production and on plasma cholesterol concentrations related to the changes in equol
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The effect of two bovine β-casein peptides on various functional properties of porcine macrophages and neutrophils: differential roles of protein kinase A and exchange protein directly activated by cyclic AMP-1 Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 R. Chronopoulou, E. Xylouri, K. Fegeros, I. Politis
The effects of two bovine β-casein peptides on the urokinase plasminogen activator (u-PA) system and superoxide anion (SA) production by porcine macrophages and neutrophils activated by phorbol myristate acetate (PMA) were investigated. Macrophages and neutrophils were obtained from fourteen weaned piglets and were cultured in vitro for 24h with or without one of two chemically synthesised peptides:
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Food processing methods influence the glycaemic indices of some commonly eaten West Indian carbohydrate-rich foods Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 P. S. Bahado-Singh, A. O. Wheatley, M. H. Ahmad, E. Y. St. A. Morrison, H. N. Asemota
Glycaemic index (GI) values for fourteen commonly eaten carbohydrate-rich foods processed by various methods were determined using ten healthy subjects. The foods studied were round leaf yellow yam (Dioscorea cayenensis), negro and lucea yams (Dioscorea rotundata), white and sweet yams (Dioscorea alata), sweet potato (Solanum tuberosum), Irish potato (Ipomoea batatas), coco yam (Xanthosoma spp.), dasheen
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White bean amylase inhibitor administered orally reduces glycaemia in type 2 diabetic rats Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 M. A. Tormo, I. Gil-Exojo, A. Romero de Tejada, J. E. Campillo
A purified pancreatic α-amylase inhibitor (α-AI) from white beans (Phaseolus vulgaris) was administered orally (100m/g body weight dissolved in 9g NaC/) for 22d to non-diabetic (ND) and type 2 diabetic (neonatal diabetes models n0-STZ and n5-STZ) male Wistar rats. Mean glycaemia (mmo/) declined from day 4 of the α-AI administration in ND rats (5·48 (sem 0·08) v. 4·39 (sem 0·13); P<0·05), n0-STZ diabetic
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Reduced isoflavone metabolites formed by the human gut microflora suppress growth but do not affect DNA integrity of human prostate cancer cells Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Marian Raschke, Kristiina Wähälä, Beatrice L. Pool-Zobel
Dietary isoflavones, such as genistein and daidzein, are metabolised by the human gut microflora. Case–control studies have disclosed a link between the formation of the daidzein metabolite equol and prostate cancer risk. We evaluated the effects of genistein, daidzein and five metabolites on two prostate cancer cell lines by determining DNA integrity and cell growth. LNCaP cells contain the T877A
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Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Gary P. Hubbard, Siegfried Wolffram, Ric de Vos, Arnaud Bovy, Jonathan M. Gibbins, Julie A. Lovegrove
Epidemiological data suggest that those who consume a diet rich in quercetin-containing foods may have a reduced risk of CVD. Furthermore, in vitro and ex vivo studies have observed the inhibition of collagen-induced platelet activation by quercetin. The aim of the present study was to investigate the possible inhibitory effects of quercetin ingestion from a dietary source on collagen-stimulated platelet
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Blood indices of selenium and mercury, and their correlations with fish intake, in young people living in Britain Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 C. J. Bates, A. Prentice, M. C. Birch, H. T. Delves, K. A. Sinclair
Relationships between Se and Hg in erythrocytes, and between these indices and intakes of fish and other foods, were studied as an adjunct to the British National Diet and Nutrition Survey (NDNS) of young people aged 4–18 years. Hg was measured in 965 packed erythrocyte samples by inductively coupled plasma mass spectrometry. Fe measurements permitted the calculation of whole-blood Hg. Erythrocyte
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Prevention of retinoic acid-induced early craniofacial abnormalities by folinic acid and expression of endothelin-/HAND in the branchial arches in mouse Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Zhaofeng Zhang, Yajun Xu, Li Li, Jing Han, Liping Zheng, Peng Liu, Yong Li
Prevention of retinoic acid-induced craniofacial abnormalities by folinic acid, and endothelin-1 (ET-1)/dHAND protein and mRNA expression were investigated in mouse embryos using the whole embryo culture, streptavidin–biotin peroxidase complex method, and whole-mount in situ hybridization. In the whole embryo culture, 1·0 and 0·1mm-folinic acid dose dependently prevented branchial region malformations
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Effects of various soya protein hydrolysates on lipid profile, blood pressure and renal function in five-sixths nephrectomized rats Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Shu-Tzu Chen, Hsin-Yi Yang, Hui-Yu Huang, Sheng-Jeng Peng, Jiun-Rong Chen
Studies have demonstrated that isolated soya protein (ISP) can slow the progression of renal injury, reduce blood pressure and improve the serum lipid profile in experimental animals and human subjects. The mechanisms and components of soya responsible have not been fully established. The present study was designed to evaluate the effects of the hydrophilic supernatant fraction (SF) and the hydrophobic
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Effect of dietary supply of butters rich either in trans-10-18:1 or in trans-11-18:1 plus cis-9, trans-11-18:2 on rabbit adipose tissue and liver lipogenic activities Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Yannick Faulconnier, Alexandre Roy, Anne Ferlay, Jean-Michel Chardigny, Denys Durand, Stephanie Lorenz, Dominique Gruffat, Yves Chilliard
Experimental butters with a high content of trans-18:1 fatty acids an/r cis-9,trans-11-18:2 (rumenic acid; RA) were fed to thirty-six New Zealand White rabbits to investigate their effects on adipose tissue (AT) and liver lipogenic activities. Animals received one of three atherogenic (0·2% cholesterol) diets containing 12% butter with either a standard fatty acid composition (rich in saturated fatty
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High phosphorus intakes acutely and negatively affect Ca and bone metabolism in a dose-dependent manner in healthy young females Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Virpi E. Kemi, Merja U. M. Kärkkäinen, Christel J. E. Lamberg-Allardt
Ca and P are both essential nutrients for bone and are known to affect one of the most important regulators of bone metabolism, parathyroid hormone (PTH). Too ample a P intake, typical of Western diets, could be deleterious to bone through the increased PTH secretion. Few controlled dose–response studies are available on the effects of high P intake in man. We studied the short-term effects of four
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Effects of increasing increments of fat- and sugar-rich snacks in the diet on energy and macronutrient intake in lean and overweight men Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-22 Nik Mazlan, Graham Horgan, Stephen Whybrow, James Stubbs
Two studies have examined the effect on energy intake and macronutrient selection of increasing increments of mandatory high-fat or high-sugar snacks into the diet in men. The present study used a within-subject, repeated-measures design. In each experiment, six lean and six overweight, unrestrained men were each studied over three 7d treatment periods, during which they were given mandatory snacks
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Mushroom intake and risk of incident disabling dementia: the Circulatory Risk in Communities Study (CIRCS) Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-19 Shoko Aoki, Kazumasa Yamagishi, Kotatsu Maruyama, Ai Ikeda, Masanori Nagao, Hiroyuki Noda, Mitsumasa Umesawa, Mina Hayama-Terada, Isao Muraki, Chika Okada, Mari Tanaka, Rie Kishida, Tomomi Kihara, Midori Takada, Yuji Shimizu, Tetsuya Ohira, Hironori Imano, Tomoko Sankai, Takeo Okada, Takeshi Tanigawa, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso
It is uncertain whether dietary intake of mushrooms rich in dietary fibre and several antioxidants is associated with a lower risk of dementia. We sought to examine prospectively the association between mushroom intake and the risk of disabling dementia. We performed a prospective study involving 3750 people aged 40 to 64 years residing in three communities who participated in an annual cardiovascular
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Association between glycaemic control and malnutrition in older adults with type 2 diabetes mellitus: a cross-sectional study Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-19 Rattiyaphon Thaenpramun, Narucha Komolsuradej, Napakkawat Buathong, Siwaluk Srikrajang
Malnutrition is a major problem among older adults with type 2 diabetes mellitus (T2DM). Some studies suggest that well glycaemic control increases the risk of frailty due to reduced intake. Therefore, it could be hypothesised that adequate glycaemic controlled patients may be at risk of malnutrition. This study aimed to examine, in older adults with T2DM, the association between adequate glycaemic
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Temporal trends of carbonated soft-drink consumption among adolescents aged 12–15 years from eighteen countries in Africa, Asia and the Americas Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-16 Lee Smith, Guillermo Felipe López Sánchez, Mark A Tully, Masoud Rahmati, Hans Oh, Karel Kostev, Laurie T. Butler, Yvonne Barnett, Helen Keyes, Jae Il Shin, Ai Koyanagi
Carbonated soft-drink consumption is detrimental to multiple facets of adolescent health. However, little is known about temporal trends in carbonated soft-drink consumption among adolescents, particularly in non-Western countries. Therefore, we aimed to examine this trend in representative samples of school-going adolescents from eighteen countries in Africa, Asia and the Americas. Cross-sectional
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Towards consistency in dietary pattern scoring: standardising scoring workflows for healthy dietary patterns using 24-h recall and two variations of a food frequency questionnair Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-16 Lizanne Arnoldy, Sarah Gauci, Annie-Claude M. Lassemillante, Joris C. Verster, Helen Macpherson, Anne-Marie Minihane, Andrew Scholey, Andrew Pipingas, David J. White
Healthy dietary patterns such as the Mediterranean diet (MeDi), Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) have been evaluated for their potential association with health outcomes. However, the lack of standardisation in scoring methodologies can hinder reproducibility and meaningful cross-study comparisons. Here we provide
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Effect of vitamin D supplementation or fortification on bone turnover markers in women: a systematic review and meta-analysis Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Nasrin Nasimi, Sanaz Jamshidi, Aida Askari, Nazanin Zolfaghari, Erfan Sadeghi, Mehran Nouri, Nick Bellissimo, Shiva Faghih
Vitamin D is a vital indicator of musculoskeletal health, as it plays an important role through the regulation of bone and mineral metabolism. This meta-analysis was performed to investigate the effects of vitamin D supplementation/fortification on bone turnover markers in women. All human randomised clinical trials reported changes in bone resorption markers (serum C-terminal telopeptide of type-I
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Nutritional composition of ultra-processed plant-based foods in the out-of-home environment: a multi-country survey with plant-based burgers Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 R. E. Vellinga, H. L. Rippin, B. G. Gonzales, E. H. M. Temme, C. Farrand, A. Halloran, B. Clough, K. Wickramasinghe, M. Santos, T. Fontes, M. J. Pires, A. C. Nascimento, S. Santiago, H. E. Burt, M. K. Brown, K. H. Jenner, R. Alessandrini, A. M. Marczak, R. Flore, Y. Sun, C. Motta
Ultra-processed plant-based foods, such as plant-based burgers, have gained in popularity. Particularly in the out-of-home (OOH) environment, evidence regarding their nutritional profile and environmental sustainability is still evolving. Plant-based burgers available at selected OOH sites were randomly sampled in Amsterdam, Copenhagen, Lisbon and London. Plant-based burgers (patty, bread and condiment)
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Study of iodine transport and thyroid hormone levels in the human placenta under different iodine nutritional status Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Min Fu, Zhiyuan Ren, Yuanpeng Gao, Haixia Zhang, Wenxing Guo, Wanqi Zhang
Iodine and thyroid hormones (TH) transport in the placenta are essential for fetal growth and development, but there is little research focus on the human placenta. The research aimed to investigate iodine and TH transport mechanisms in the human placenta. The placenta was collected from sixty healthy pregnant women. Urinary iodine concentration (UIC), serum iodine concentration (SIC), placenta iodine
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Preoperative dietitian-led Very Low Calorie Diet (VLCD) Clinic for adults living with obesity undergoing gynaecology, laparoscopic cholecystectomy and hernia repair procedures: a pilot parallel randomised controlled trial Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Sally B. Griffin, Michelle A. Palmer, Esben Strodl, Rainbow Lai, Teong L. Chuah, Matthew J. Burstow, Lynda J. Ross
Obesity can increase the risk of postoperative complications. Despite increased demand for patients living with obesity to lose weight prior to common surgical procedures, the impact of intentional weight loss on surgical outcomes is largely unknown. We aimed to conduct a pilot study to assess the feasibility of a full-scale randomised controlled trial (RCT) to examine the effect of preoperative dietitian-led
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Fish oil supplement use modifies the relationship between dietary oily fish intake and plasma n-3 PUFA levels: an analysis of the UK Biobank Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Joanna Aldoori, Michael A. Zulyniak, Giles J. Toogood, Mark A. Hull
Observational evidence linking dietary n-3 PUFA intake and health outcomes is limited by a lack of robust validation of dietary intake using blood n-3 PUFA levels and potential confounding by fish oil supplement (FOS) use. We investigated the relationship between oily fish intake, FOS use and plasma n-3 PUFA levels in 121 650 UK Biobank (UKBB) participants. Ordinal logistic regression models, adjusted
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The association of dietary antioxidants and the inflammatory potential of the diet with poor physical function and disability in older Australian men: the Concord Health and Ageing in Men Project Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Daniela Wizgier, Ying Meng, Arpita Das, Vasi Naganathan, Fiona Blyth, David G. Le Couteur, David J. Handelsman, Louise M. Waite, Rosilene V. Ribeiro, Nitin Shivappa, James R. Hébert, Vasant Hirani
Our objective was to evaluate the association of antioxidant intake and the inflammatory potential of the diet with functional decline in older men. A diet history questionnaire was used to collect dietary intake data from men aged ≥ 75 years (n 794) participating in the Concord Health and Aging in Men Project cohort study. Intake of vitamins A, C, E and Zn were compared with the Australian Nutrient
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Ingestion of a variety of non-animal-derived dietary protein sources results in diverse postprandial plasma amino acid responses which differ between young and older adults Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Ino van der Heijden, Sam West, Alistair J. Monteyne, Tim J. A. Finnigan, Doaa R. Abdelrahman, Andrew J. Murton, Francis B. Stephens, Benjamin T. Wall
Whole-body tissue protein turnover is regulated, in part, by the postprandial rise in plasma amino acid concentrations, although minimal data exist on the amino acid response following non-animal-derived protein consumption. We hypothesised that the ingestion of novel plant- and algae-derived dietary protein sources would elicit divergent plasma amino acid responses when compared with vegan- and animal-derived
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Nutrients or processing? An analysis of food and drink items from the UK National Diet and Nutrition Survey based on nutrient content, the NOVA classification and front of package traffic light labelling Briti. J. Nutr. (IF 3.6) Pub Date : 2024-01-15 Samuel J. Dicken, Rachel L. Batterham, Adrian Brown
UK front of package labelling (FOPL) informs consumers on the nutrient content of food. However, FOPL does not consider food processing, and with the UK government being urged to act on ultra-processed food (UPF), whether UPF should be added to FOPL is unclear. This study compared food and drink in the UK National Diet and Nutrition Survey (NDNS) Intake24 database based on FOPL, nutrient content and