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Decorated Vesicles as Prebiont Systems (a Hypothesis) Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-12-11 Martin Fisk, Radu Popa
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Enhancement of Prebiotic Peptide Formation in Cyclic Environments Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-10-28 Hayley Boigenzahn, Praful Gagrani, John Yin
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Sequential Amplification of Amino Acid Enantiomeric Excess by Conglomerate and Racemic Compound: Plausible Prebiotic Route Towards Homochirality Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-10-13 A. Sharma
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Did Salts in Seawater Play an Important Role in the Adsorption of Molecules on Minerals in the Prebiotic Earth? The Case of the Adsorption of Thiocyanate onto Forsterite-91 Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-09-07 Giulio Wilgner Ferreira, Rafael Block Samulewski, Flávio Francisco Ivashita, Andrea Paesano, Alexandre Urbano, Dimas Augusto Morozin Zaia
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Parity Violation Energy Difference Calculation of Atropisomers Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-06-14 Dhanalakshmi Vadivel, Daniele Dondi
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Magnetic Circular Dichroism in Archean Stratospheric Oxygen: Enantiomeric Excess of Amino Acids Produced in Volcanic Plumes Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-06-06 A. Sharma
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Nonenzymatic Template-Directed Primer Extension Using 2′-3′ Cyclic Nucleotides Under Wet-Dry Cycles Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-05-27 Shikha Dagar, Susovan Sarkar, Sudha Rajamani
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Behaviour and the Origin of Organisms Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2023-05-11 Matthew Egbert, Martin M. Hanczyc, Inman Harvey, Nathaniel Virgo, Emily C. Parke, Tom Froese, Hiroki Sayama, Alexandra S. Penn, Stuart Bartlett
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Glycine to Oligoglycine via Sequential Trimetaphosphate Activation Steps in Drying Environments Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-12-10 Hayley Boigenzahn, John Yin
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Thymine Adsorption onto Cation Exchanged Montmorillonite Clay: Role of Biogenic Divalent Metal Cations in Prebiotic Processes of Chemical Evolution Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-11-24 Satish Chandra Sati, Chandra Kala Pant, Preeti Bhatt, Yogesh Pandey
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Mathematical Models of Chiral Symmetry-breaking – A Review of General Theories, and Adiabatic Approximations of the APED System Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-11-23 Priscila C. Diniz, Jonathan A. D. Wattis, Fernando P. da Costa
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Evolutionary Approach to Biological Homochirality Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-11-18 Konstantin K. Konstantinov, Alisa F. Konstantinova
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Evaluating Mineral Lattices as Evolutionary Proxies for Metalloprotein Evolution Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-11-16 Kenneth N. McGuinness, Gunnar W. Klau, Shaunna M. Morrison, Elisha K. Moore, Jan Seipp, Paul G. Falkowski, Vikas Nanda
Protein coordinated iron-sulfur clusters drive electron flow within metabolic pathways for organisms throughout the tree of life. It is not known how iron-sulfur clusters were first incorporated into proteins. Structural analogies to iron-sulfide minerals present on early Earth, suggest a connection in the evolution of both proteins and minerals. The availability of large protein and mineral crystallographic
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Introduction to Origins of Biological Homochirality. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-09-01 Axel Brandenburg,David Hochberg
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A Cofactor-Based Mechanism for the Origin of the Genetic Code Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-09-08 Juan A. Martínez Giménez, Rafael Tabares Seisdedos
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Symmetry Breaking by Consecutive Amplification: Efficient Paths to Homochirality Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-08-19 Laura Huber, Oliver Trapp
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Biological Homochirality and the Search for Extraterrestrial Biosignatures Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-08-15 Marcelo Gleiser
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Asymmetric Autocatalysis as an Efficient Link Between the Origin of Homochirality and Highly Enantioenriched Compounds Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-08-12 Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto
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Competitive interaction of Mn(II) and Fe(II) cations with the high-affinity Mn-binding site of the photosystem II: evolutionary aspect Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-07-07 E. R. Lovyagina, B. К. Semin
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Frontiers in Prebiotic Chemistry and Early Earth Environments Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-07-07 Ulrich F. Müller, Jamie Elsila, Dustin Trail, Saurja DasGupta, Claudia-Corina Giese, Craig R. Walton, Zachary R. Cohen, Tomislav Stolar, Ramanarayanan Krishnamurthy, Timothy W. Lyons, Karyn L. Rogers, Loren Dean Williams
The Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium is a community of researchers seeking to understand the origins of life on Earth and in the universe. PCE3 is one of five Research Coordination Networks (RCNs) within NASA’s Astrobiology Program. Here we report on the inaugural PCE3 workshop, intended to cross-pollinate, transfer information, promote cooperation, break down disciplinary
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On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-07-07 R. Fernando Martínez, Louis A. Cuccia, Cristóbal Viedma, Pedro Cintas
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Spontaneous Emergence of Transient Chirality in Closed, Reversible Frank-like Deterministic Models Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-06-10 Thomas Buhse, Jean-Claude Micheau
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Gaia as Solaris: An Alternative Default Evolutionary Trajectory Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-04-20 Srdja Janković, Ana Katić, Milan M. Ćirković
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Molecular Self-Assembly as a Trigger of Life Origin and Development Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-04-20 Dmitry V. Zlenko, Anatoly M. Zanin, Sergey V. Stovbun
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The Effect of Goethites on the Polymerization of Glycine and Alanine Under Prebiotic Chemistry Conditions Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-01-22 João Paulo T. Baú, Cristine E. A. Carneiro, Antônio Carlos S. da Costa, Daniel F. Valezi, Eduardo di Mauro, Eduardo Pilau, Dimas A. M. Zaia
After pre concentration of monomers, polymerization is the second most important step for molecular evolution. The formation of peptides is an important issue for prebiotic chemistry and consequently for the origin of life. In this work, goethite was synthesized by two different routes, named goethite-I and goethite-II. Although both samples are goethite, Far-FT-IR spectroscopy and EPR spectroscopy
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The Effect of Goethites on the Polymerization of Glycine and Alanine Under Prebiotic Chemistry Conditions. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-01-22 João Paulo T Baú,Cristine E A Carneiro,Antônio Carlos S da Costa,Daniel F Valezi,Eduardo di Mauro,Eduardo Pilau,Dimas A M Zaia
After pre concentration of monomers, polymerization is the second most important step for molecular evolution. The formation of peptides is an important issue for prebiotic chemistry and consequently for the origin of life. In this work, goethite was synthesized by two different routes, named goethite-I and goethite-II. Although both samples are goethite, Far-FT-IR spectroscopy and EPR spectroscopy
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Ribozyme Mutagenic Evolution: Mechanisms of Survival Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2022-01-07 Carolina Diaz Arenas, Aleksandra Ardaševa, Jonathan Miller, Alexander S. Mikheyev, Yohei Yokobayashi
Primeval populations replicating at high error rates required a mechanism to overcome the accumulation of mutations and information deterioration. Known strategies to overcome mutation pressures include RNA processivity, epistasis, selection, and quasispecies. We investigated the mechanism by which small molecular ribozyme populations can survive under high error rates by propagating several lineages
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Computational Study of the Stability of Natural Amino Acid isomers Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-11-05 Stefano Crespi, Dhanalakshmi Vadivel, Alfredo Bellisario, Daniele Dondi
The secular debate on the origin of life on our planet represents one of the open challenges for the scientific community. In this endeavour, chemistry has a pivotal role in disclosing novel scenarios that allow us to understand how the formation of simple organic molecules would be possible in the early primitive geological ages of Earth. Amino acids play a crucial role in biological processes. They
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Computational Study of the Stability of Natural Amino Acid isomers. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-11-05 Stefano Crespi,Dhanalakshmi Vadivel,Alfredo Bellisario,Daniele Dondi
The secular debate on the origin of life on our planet represents one of the open challenges for the scientific community. In this endeavour, chemistry has a pivotal role in disclosing novel scenarios that allow us to understand how the formation of simple organic molecules would be possible in the early primitive geological ages of Earth. Amino acids play a crucial role in biological processes. They
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The Codon Usage in the Minimal Natural Cell Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-10-25 Piotr H. Pawłowski
A statistical analysis of the variation in contents with the size of the current known smallest genomes, N. deltocephalinicola, C. ruddii, N. equitans, and M. genitalium, enabled the indication of a minimal set of codons capable of naturally building a modern-type free-living unicellular organism in an early stage of evolution. Using a linear regression model, the potential codon distribution in the
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Does Stochasticity Favour Complexity in a Prebiotic Peptide-Micelle System? Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-09-03 Rowena Ball, John Brindley
A primordial environment that hosted complex pre- or proto-biochemical activity would have been subject to random fluctuations. A relevant question is then: What might be the optimum variance of such fluctuations, such that net progress could be made towards a living system? Since lipid-based membrane encapsulation was undoubtedly a key step in chemical evolution, we used a peptide-micelle system in
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Does Stochasticity Favour Complexity in a Prebiotic Peptide-Micelle System? Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-09-03 Rowena Ball,John Brindley
A primordial environment that hosted complex pre- or proto-biochemical activity would have been subject to random fluctuations. A relevant question is then: What might be the optimum variance of such fluctuations, such that net progress could be made towards a living system? Since lipid-based membrane encapsulation was undoubtedly a key step in chemical evolution, we used a peptide-micelle system in
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How the Geomagnetic Field Influences Life on Earth – An Integrated Approach to Geomagnetobiology Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-08-07 Erdmann, Weronika, Kmita, Hanna, Kosicki, Jakub Z., Kaczmarek, Łukasz
Earth is one of the inner planets of the Solar System, but – unlike the others – it has an oxidising atmosphere, relatively stable temperature, and a constant geomagnetic field (GMF). The GMF does not only protect life on Earth against the solar wind and cosmic rays, but it also shields the atmosphere itself, thus creating relatively stable environmental conditions. What is more, the GMF could have
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Emergent Bioanalogous Properties of Blockchain-based Distributed Systems Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-08-07 Abramov, Oleg, Bebell, Kirstin L., Mojzsis, Stephen J.
We apply a novel definition of biological systems to a series of reproducible observations on a blockchain-based distributed virtual machine (dVM). We find that such blockchain-based systems display a number of bioanalogous properties, such as response to the environment, growth and change, replication, and homeostasis, that fit some definitions of life. We further present a conceptual model for a
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How the Geomagnetic Field Influences Life on Earth - An Integrated Approach to Geomagnetobiology. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-08-07 Weronika Erdmann,Hanna Kmita,Jakub Z Kosicki,Łukasz Kaczmarek
Earth is one of the inner planets of the Solar System, but - unlike the others - it has an oxidising atmosphere, relatively stable temperature, and a constant geomagnetic field (GMF). The GMF does not only protect life on Earth against the solar wind and cosmic rays, but it also shields the atmosphere itself, thus creating relatively stable environmental conditions. What is more, the GMF could have
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Emergent Bioanalogous Properties of Blockchain-based Distributed Systems. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-08-07 Oleg Abramov,Kirstin L Bebell,Stephen J Mojzsis
We apply a novel definition of biological systems to a series of reproducible observations on a blockchain-based distributed virtual machine (dVM). We find that such blockchain-based systems display a number of bioanalogous properties, such as response to the environment, growth and change, replication, and homeostasis, that fit some definitions of life. We further present a conceptual model for a
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Plausible Emergence and Self Assembly of a Primitive Phospholipid from Reduced Phosphorus on the Primordial Earth Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-07-19 Michael O. Gaylor, Pere Miro, Bess Vlaisavljevich, Ashen Anuradha Suduweli Kondage, Laura M. Barge, Arthur Omran, Patrick Videau, Vaille A. Swenson, Lucas J. Leinen, Nathaniel W. Fitch, Krista L. Cole, Chris Stone, Samuel M. Drummond, Kayli Rageth, Lillian R. Dewitt, Sarah González Henao, Vytis Karanauskus
How life arose on the primitive Earth is one of the biggest questions in science. Biomolecular emergence scenarios have proliferated in the literature but accounting for the ubiquity of oxidized (+ 5) phosphate (PO43−) in extant biochemistries has been challenging due to the dearth of phosphate and molecular oxygen on the primordial Earth. A compelling body of work suggests that exogenous schreibersite
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Role of the Interchangeable Cations on the Sorption of Fumaric and Succinic Acids on Montmorillonite and its Relevance in Prebiotic Chemistry Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-07-12 A. Meléndez-López, M. Colín-García, F. Ortega-Gutiérrez, J. Cruz-Castañeda
It has been proposed that clays could have served as key factors in promoting the increase in complexity of organic matter in primitive terrestrial and extraterrestrial environments. The aim of this work is to study the adsorption–desorption of two dicarboxylic acids, fumaric and succinic acids, onto clay minerals (sodium and iron montmorillonite). These two acids may have played a role in prebiotic
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Quadruplex World Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-07-02 Besik Kankia
The RNA world hypothesis relies on the double-helix complementarity principle for both replication and catalytic activity of RNA. However, the de novo appearance of the complementarity rules, without previous evolution steps, is doubtful. Another major problem of the RNA world is its isolated nature, making it almost impossible to accommodate the genetic code and transform it into modern biochemistry
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Possible Ancestral Functions of the Genetic and RNA Operational Precodes and the Origin of the Genetic System Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-06-07 Juan A. Martínez-Giménez, Rafael Tabares-Seisdedos
The origin of genetic systems is the central problem in the study of the origin of life for which various explanatory hypotheses have been presented. One model suggests that both ancestral transfer ribonucleic acid (tRNA) molecules and primitive ribosomes were originally involved in RNA replication (Campbell 1991). According to this model the early tRNA molecules catalyzed their own self-loading with
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Correction to Volume 50 Issues 3–4 Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-04-10
A correction to this paper has been published: https://doi.org/10.1007/s11084-021-09607-2
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Histidine Self-assembly and Stability on Mineral Surfaces as a Model of Prebiotic Chemical Evolution: An Experimental and Computational Approach Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-03-31 D. Madrigal-Trejo, P.S. Villanueva-Barragán, R. Zamudio-Ramírez, K. E. Cervantes-de la Cruz, I. Mejía-Luna, E. Chacón-Baca, A. Negrón-Mendoza, S. Ramos-Bernal, A. Heredia-Barbero
The abiotic synthesis of histidine under experimental prebiotic conditions has proven to be chemically promising and plausible. Within this context, the present results suggest that histidine amino acid may function as a simple prebiotic catalyst able to enhance amino acid polymerization. This work describes an experimental and computational approach to the self-assembly and stabilization of DL-histidine
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Did Cyclic Metaphosphates Have a Role in the Origin of Life? Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-03-15 Thomas Glonek
How life began still eludes science life, the initial progenote in the context presented herein, being a chemical aggregate of primordial inorganic and organic molecules capable of self-replication and evolution into ever increasingly complex forms and functions. Presented is a hypothesis that a mineral scaffold generated by geological processes and containing polymerized phosphate units was present
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Molecular Adsorption on Cold Gas-Phase Hydrogen-Bonded Clusters of Chiral Molecules Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-02-15 Hiromori Murashima, Akimasa Fujihara
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Toward Molecular Cooperation by De Novo Peptides Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-02-10 Izabela K. Sibilska-Kaminski, John Yin
Theoretical models of the chemical origins of life depend on self-replication or autocatalysis, processes that arise from molecular interactions, recruitment, and cooperation. Such models often lack details about the molecules and reactions involved, giving little guidance to those seeking to detect signs of interaction, recruitment, or cooperation in the laboratory. Here, we develop minimal mathematical
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Alien Oceans: The Search for Life in the Depths of Space by Kevin Peter Hand, Princeton University Press, 2020, 304 Pages Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2021-01-05 Peter R. Bahn
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Investigating the Evolution and Development of Biological Systems from the Perspective of Thermo-Kinetics and Systems Theory Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-12-03 Mohammad Amin Boojari
Life itself is grander than the sum of its constituent molecules. Any living organism may be regarded as a part of a dissipative process that connects irreversible energy consumption with growth, reproduction, and evolution. Under energy-fuelled, far-from-equilibrium conditions, chemical systems capable of exponential growth can manifest a specific form of stability– dynamic kinetic stability (DKS)
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Chiral Symmetry Breaking in Large Peptide Systems. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-09-18 Konstantin K Konstantinov,Alisa F Konstantinova
Chiral symmetry breaking in far from equilibrium systems with large number of amino acids and peptides, like a prebiotic Earth, was considered. It was shown that if organic catalysts were abundant, then effective averaging of enantioselectivity would prohibit any symmetry breaking in such systems. It was further argued that non-linear (catalytic) reactions must be very scarce (called the abundance
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Plausibility of the Formose Reaction in Alkaline Hydrothermal Vent Environments. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-08-04 Arthur Omran
Prebiotic processes required a reliable source of free energy and complex chemical mixtures that may have included sugars. The formose reaction is a potential source of those sugars. At moderate to elevated temperature and pH ranges, these sugars rapidly decay. Here it is shown that CaCO3-based chemical gardens catalyze the formose reaction to produce glucose, ribose, and other monosaccharides. These
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Survival of the Halophilic Archaeon Halovarius luteus after Desiccation, Simulated Martian UV Radiation and Vacuum in Comparison to Bacillus atrophaeus. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-07-02 Niloofar Feshangsaz,Farid Semsarha,Saeed Hesami Tackallou,Kamran Nazmi,Euan P Monaghan,Andreas Riedo,Jack J W A van Loon
Extraterrestrial environments influence the biochemistry of organisms through a variety of factors, including high levels of radiation and vacuum, temperature extremes and a lack of water and nutrients. A wide variety of terrestrial microorganisms, including those counted amongst the most ancient inhabitants of Earth, can cope with high levels of salinity, extreme temperatures, desiccation and high
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Parity Violation Energy of Biomolecules - V: Protein Metal Centers. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-06-20 Francesco Faglioni,Bianca Fracassini,Luca Perrone
The parity-violation difference between mirror images of chiral metal centers found in naturally occurring proteins and enzymes is computed at the Dirac-Hartree-Fock level, for both equilibrium and transition state configurations. The systems, selected on the likelihood of yielding high parity violation energies based on atomic mass and coordination geometry, are extracted from: type I Blue Copper
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The Prebiotic Provenance of Semi-Aqueous Solvents. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-05-09 Jennifer L Lago,Bradley T Burcar,Nicholas V Hud,Rio Febrian,Christopher Mehta,Paul J Bracher,Zachary D Atlas,Matthew A Pasek
The numerous and varied roles of phosphorylated organic molecules in biochemistry suggest they may have been important to the origin of life. The prominence of phosphorylated molecules presents a conundrum given that phosphorylation is a thermodynamically unfavorable, endergonic process in water, and most natural sources of phosphate are poorly soluble. We recently demonstrated that a semi-aqueous
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Chirality Driven Twisting as a Driving Force of Primitive Folding in Binary Mixtures. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-04-30 Dmitry V Zlenko,Aleksey A Skoblin,Alexander S Vedenkin,Mariya G Mikhaleva,Anatoly M Zanin,Vsevolod A Tverdislov,Sergey V Stovbun
The N-trifluoroacetylated α-aminoalcohols (TFAAAs) are able to form quasi-one-dimensional supramolecular fibers (strings) when chirally pure, and isometric precipitates in the racemate. The strings' formation leads to the reversible gelation of the solution. The fresh gels occupy all the available volume, however during the incubation, they contract and concentrate in the central region of the tube
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Alteration and Stability of Complex Macromolecular Amino Acid Precursors in Hydrothermal Environments. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-04-20 Walaa Elmasry,Yoko Kebukawa,Takeo Kaneko,Yumiko Obayashi,Hitoshi Fukuda,Yoshiyuki Oguri,Kensei Kobayashi
The early Solar System comprised a broad area of abiotically created organic compounds, including interstellar organics which were integrated into planetesimals and parent bodies of meteorites, and eventually delivered to the early Earth. In this study, we simulated interstellar complex organic compounds synthesized by proton irradiation of a gas mixture of CO, NH3, and H2O, which are known to release
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Unexpected Thiocyanate Adsorption onto Ferrihydrite Under Prebiotic Chemistry Conditions. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-04-07 Dimas A M Zaia,Paulo C G de Carvalho,Rafael B Samulewski,Rodrigo de Carvalho Pereira,Cássia Thaïs B V Zaia
The most crucial role played by minerals was in the preconcentration of biomolecules or precursors of biomolecules in prebiotic seas. If this step had not occurred, molecular evolution would not have occurred. Thiocyanate is an important molecule in the formation of biomolecules as well as a catalyst for prebiotic reactions. The adsorption of thiocyanate onto ferrihydrite was carried out under pH and
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Symphony in C: Carbon and the Evolution of (Almost) Everything by Robert M. Hazen, W.W. Norton & Company, 2019. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-06-01 Peter R Bahn
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On A Hypothetical Mechanism of Interstellar Life Transfer Trough Nomadic Objects. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-02-07 Grzegorz Sadlok
Lethal radiation, low vacuum pressure and low temperatures - this is how space welcomes organisms. Crossing of immense interstellar distances inflates the exposure time of biological material to harmful space conditions. This paper discusses the intriguing possibility of a life-bearing exoplanet being ejected from its planetary system and carrying life across interstellar distances (nomadic = free
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Reactivity of Metabolic Intermediates and Cofactor Stability under Model Early Earth Conditions. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2020-01-25 Thora R Maltais,David VanderVelde,Douglas E LaRowe,Aaron D Goldman,Laura M Barge
Understanding the emergence of metabolic pathways is key to unraveling the factors that promoted the origin of life. One popular view is that protein cofactors acted as catalysts prior to the evolution of the protein enzymes with which they are now associated. We investigated the stability of acetyl coenzyme A (Acetyl Co-A, the group transfer cofactor in citric acid synthesis in the TCA cycle) under
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Membranes Composed of Lipopeptides and Liponucleobases Inspired Protolife Evolution. Orig. Life Evol. Biosph. (IF 2.0) Pub Date : 2019-12-27 Gordon D Sproul
Amino acids and peptides have been demonstrated to form lipoamino acids and lipopeptides under presumed prebiotic conditions, and readily form liposomes. Of the common nucleobases, adenine forms a liponucleobase even below 100 °C. Adenine as well as other nucleobases can also be derivatized with ethylene carbonate (and likely other similar compounds) onto which fatty acids can be attached. The fatty