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Effects of pulsed Nd:YAG laser kernel irradiation on maize (Zea mays L.): Insights into germination, gas exchange, photosynthetic pigments, and morphological modifications J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-03-01 Rashida Perveen, Yasir Jamil, Arwa Abdulkreem AL-Huqail, Ibtisam Mohammed Alsudays, Suliman Mohammed Suliman Alghanem, Qasim Ali, Farah Saeed, Muhammad Azeem, Muhammad Rizwan, Sami Asir Al-Robai
Energy has always been the most concerned topic worldwide due to its large consumption. Among various types of energies, light has amazing characteristics and have interesting effects on living organisms. Interest is increasing in the use of laser kernel treatment as an environment friendly physical technique for better results in agronomic crops, but the work is still in progress. The present study
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The impact of methylene blue photosensitizer, aPDT and a calcium hydroxide-based paste on the physicochemical and mechanical characteristics of root canal dentin and the bonding interface of fiberglass posts J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-03-01 Henrico Badaoui Strazzi-Sahyon, Henrique Augusto Banci, Thalya Fernanda Horsth Maltarollo, Carolina Martins Teixeira Martinez, Eloísa Alexo Rocha, Roberto Braga Figueiredo, Dayana Cristina Silva Garcia, Carlos José Leopoldo Constantino, Rubens Spin-Neto, Marco Antonio Hungaro Duarte, Luciano Tavares Angelo Cintra, Paulo Henrique dos Santos, Gustavo Sivieri-Araujo
To investigate the influence of methylene blue (MB)-mediated antimicrobial photodynamic therapy (aPDT) and calcium hydroxide (CH) medication on the mechanical characteristics, degree of conversion (DC), quantification, and volume of gaps at the adhesive interface of glass fiber posts (GFPs) luted to distinct thirds of root canal dentin. Additionally, the microhardness (MH), elastic modulus (Eit), morphology
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Fabrication of hyaluronic acid-altered gold complex delivery for head and neck squamous cell carcinoma therapy with high antitumor efficacy and low in vivo toxicity J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-03-01 Shizhi He, Jiaming Chen, Yanming Zhao, Ru Wang, Yurong He, Shaoshi Chen, Yifan Yang, Changyu Zhu, Jingyang Zhao, Jugao Fang
The use of multifunctional nanomedicines in the treatment of tumors is gaining popularity. Here, we constructed a nanodrug delivery system (HA/Au-PDA@CZT) that targets tumors and responds to pH and near-infrared (NIR) dual stimuli. By precisely interacting with an overexpressed CD44 receptor in specific cancer cells, hyaluronic acid (HA) is coated on the Au-PDA NP surface for tumor-targeting abilities
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Borneol serves as an adjuvant agent to promote the cellular uptake of curcumin for enhancing its photodynamic fungicidal efficacy against Candida albicans J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-26 Zhenlong Zhou, Shengli Wang, Penghui Fan, Xiaofeng Meng, Xinyu Cai, Wen Wang, Lin Ma, Hang Ma, Jianyu Su
(), a major opportunistic pathogenic fungus, is known to cause superficial skin infections. Unfortunately, the misuse of antibiotics has led to the emergence of drug resistance in fungi. Antimicrobial photodynamic therapy (aPDT), a non-antibiotic alternative, has shown potential in treating drug-resistant fungal infections. Curcumin is a photodynamically active phytochemical whose photodynamic fungicidal
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Investigation of healing strategies in a rat corneal opacity model with polychromatic light and stem cells injection J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-24 Betül Seher Uysal, Burcu Sarıkaya, Saadet Özen Akarca Dizakar, Gülnur Take Kaplanoğlu, Menemşe Gümüşderelioğlu
Corneal opacities are a major cause of vision loss worldwide. However, the current therapies are suboptimal to manage the corneal wound healing process. Therefore, there is an obvious need to develop new treatment strategies that are efficient in promoting wound healing in patients with severe corneal disorders. In this study, we investigated and compared the efficacy of adipose-derived mesenchymal
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Skin-derived precursor conditioned medium alleviated photoaging via early activation of TGF-β/Smad signaling pathway by thrombospondin1: In vitro and in vivo studies J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-22 Yiming Li, Lingyun Zhao, Shiyi Li, Danhua Ruan, Lidan Xiong, Jie Tang, Meng Hu, Yixin Wang, Wen Huang, Li Li, Zhiwei Zhao
Photoaging is one major exogenous factor of skin aging. Efficacy and safety of current anti-photoaging therapies remained to be improved. Our previous studies indicated that skin-derived precursors (SKPs) alleviated photodamage by early activation of TGF-β/Smad signaling pathway thrombospondin1 (TSP1). However, the research concerning SKP conditioned medium (SKP-CM) has never been reported. In the
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The regulation of light quality on the substance production and photosynthetic activity of Dunaliella bardawil J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-21 Cuili Jin, Yan Zhu, Jiajie You, Qiuyan Yu, Qing Liu, Xiaojian Zhou
To study the influence and regulation of light quality on the microalgal photosynthetic activity and production of biomass and substances, green alga was cultured in this study under the monochromatic red light (7R0B), blue light (0R7B), and their combinations with different ratios (xRyB, x + y = 7), as well as a control of white light (W). The results demonstrated that the only advantage for control
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Validation and application of caged Z-DEVD-aminoluciferin bioluminescence for assessment of apoptosis of wild type and TLR2-deficient mice after ischemic stroke J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-21 P. Josić Dominović, M. Dobrivojević Radmilović, S. Srakočić, I. Mišerić, S. Škokić, S. Gajović
Programmed cell death or apoptosis is a critically important mechanism of tissue remodeling and regulates conditions such as cancer, neurodegeneration or stroke. The aim of this research article was to assess the caged -DEVD-aminoluciferin substrate for monitoring of apoptosis after ischemic stroke in TLR2-deficient mice and their TLR2-expressing counterparts. Postischemic inflammation is a significant
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Non-lethal exposure to short-wavelength light-emitting diodes modulates tight-junction structure in human corneal epithelial cells via cAMP-dependent signaling J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-15 Tsan-Chi Chen, Shu-Wen Chang
Light-emitting diodes (LED)-derived lights have been widely used as a medical treatment in photobiomodulation (PBM). However, the PBM effects in ophthalmology are less well investigated. Herein, we explored the effect of LED-generated light on the tight-junction (TJ) formation in human corneal epithelial cells (HCEs). The HCEs were separately exposed to monochromatic LEDs at wavelengths of 365 nm (UVA)
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Genetically encoded fluorescent sensor to monitor intracellular arginine methylation J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-15 Fangrong Zhang, Helmut Bischof, Sandra Burgstaller, Benjamin M.R. Bourgeois, Roland Malli, Tobias Madl
Arginine methylation (ArgMet), as a post-translational modification, plays crucial roles in RNA processing, transcriptional regulation, signal transduction, DNA repair, apoptosis and liquid-liquid phase separation (LLPS). Since arginine methylation is associated with cancer pathogenesis and progression, protein arginine methyltransferases have gained interest as targets for anti-cancer therapy. Despite
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Spectral insights: Navigating the frontiers of biomedical and microbiological exploration with Raman spectroscopy J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-15 Elvin S. Allakhverdiev, Bekzhan D. Kossalbayev, Asemgul K. Sadvakasova, Meruyert O. Bauenova, Ayaz M. Belkozhayev, Oleg V. Rodnenkov, Tamila V. Martynyuk, Georgy V. Maksimov, Suleyman I. Allakhverdiev
Raman spectroscopy (RS), a powerful analytical technique, has gained increasing recognition and utility in the fields of biomedical and biological research. Raman spectroscopic analyses find extensive application in the field of medicine and are employed for intricate research endeavors and diagnostic purposes. Consequently, it enjoys broad utilization within the realm of biological research, facilitating
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Biphasic photobiomodulation of inflammation in mouse models of common wounds, infected wounds, and diabetic wounds J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-13 Jianshen Hu, Xiaoxi Dong, Yue Lv, Dian Hu, Duheng Fei, Huajiang Dong, Bin Liu, Hongxiao Li, Huijuan Yin
Bidirectional photobiomodulation (PBM) therapy is an active research area. However, most studies have focused on its dependence on optical parameters rather than on its tissue-dependent effects. We constructed mouse models of wounds in three inflammatory states (normal, low, and high levels of inflammations) to assess the bidirectional regulatory effect of PBM on inflammation. Mice were divided into
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Effects of ultraviolet radiation on cellular functions of the cyanobacterium Synechocystis sp. PCC 6803 and its recovery under photosynthetically active radiation J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-09 Prashant R. Singh, Amit Gupta, Ashish P. Singh, Jyoti Jaiswal, Rajeshwar P. Sinha
Cyanobacteria are photosynthetic organisms and challenged by large number of stresses, especially by ultraviolet radiation (UVR). UVR primarily impacts lipids, proteins, DNA, photosynthetic performance, which lowers the fitness and production of cyanobacteria. UVR has a catastrophic effect on cyanobacterial cells and eventually leads to cell death. UVR tolerance in the was poorly studied. Therefore
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Exceptional anticancer photodynamic properties of [1,4-Bis(3,6,9,12-Tetraoxatridec-1-yloxy)phthalocyaninato]zinc(II) J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-06 Christophe Nguyen, Isabelle Toubia, Kamel Hadj-Kaddour, Lamiaa M.A. Ali, Laure Lichon, Charlotte Cure, Marwan Kobeissi, Fabrice Odobel, Magali Gary-Bobo
Phthalocyanines have been described as effective photosensitizers for photodynamic therapy and are therefore, being studied for their biomedical applications. The metalation of photosensitizers can improve their photodynamic therapy potential. Here, we focus on the biological properties of [1,4-Bis(3,6,9,12-Tetraoxatridec-1-yloxy)phthalocyaninato]zinc(II) (ZnPc(αEG)) and demonstrate its exceptional
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Nonvisual system-mediated body color change in fish reveals nonvisual function of Opsin 3 in skin J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-04 Zihao Zhang, Chenchen Shi, Jian Han, Xiaoyu Ge, Na Li, Yang Liu, Jing Huang, Shixi Chen
Body-color changes in many poikilothermic animals can occur quickly. This color change is generally initiated by visual system, followed by neuromuscular or neuroendocrine control. We have previously showed that the ventral skin color of the large yellow croaker () presents golden yellow in dark environment and quickly changes to silvery white in light environment. In the present study, we found that
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Integrated transcriptomic and proteomic analyses uncover the early response mechanisms of Catharanthus roseus under ultraviolet-B radiation J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-04 Zhuoheng Zhong, Mengmin Wu, Tiancai Yang, Xiaoyue Nan, Shuyao Zhang, Lin Zhang, Limin Jin
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Effects of antimicrobial photodynamic therapy with photodithazine® on methicillin-resistant Staphylococcus aureus (MRSA): Studies in biofilms and experimental model with Galleria mellonella J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-02-03 Beatriz Müller N. Souza, Alejandro Guillermo Miñán, Isabelle Ribeiro Brambilla, Juliana Guerra Pinto, Maíra Terra Garcia, Juliana Campos Junqueira, Juliana Ferreira-Strixino
infections are a severe health problem due to the high mortality rate. Conventional treatment of these infections is the administration of antibiotics. However, its indiscriminate use can select resistant microorganisms. Thus, it is necessary to develop alternatives for antibiotic therapy. Antimicrobial Photodynamic Therapy (aPDT), a therapeutic method that associates a photosensitizer (PS), a light
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Bioluminescence measurement of superoxide anion in infertile men with oxidative stress J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-28 Jahangir Mohammadzadeh, Mohammad R. Raoufy, Milad Nazari, Reza H. Sajedi
Infertility is such an important issue in society today. In some cases of male infertility, the main cause is oxidative stress and the presence of reactive oxygen species in the environment or in sperm cells. All current techniques that measure oxidative stress, including the nitroblue tetrazolium Test, DNA Fragmentation Index, Malondialdehyde, and Endz Test are qualitative and semi-quantitative. These
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Photochemical stability of chitosan films doped with cannabis oil J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-23 Dorota Chełminiak-Dudkiewicz, Aleksander Smolarkiewicz-Wyczachowski, Marta Ziegler-Borowska, Halina Kaczmarek
The effect of UV radiation from three different sources on chitosan (CS) films containing the addition of 10% by weight of cannabis oil was investigated. Cannabis oil (CBD) alone exposed to UV is unstable, but its photostability significantly increases in the chitosan matrix. The course of photochemical reactions, studied by FTIR spectroscopy, is slow and inefficient in chitosan with CBD, even under
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Enhancing the photodynamic effect of curcumin through modification with TiO2 nanoparticles and cationic polymers J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-26 Mingmei Ji, Yulan Wang, Wenhua Su, Liwen Chen, Yuzhe Liu, Yuwei Yang, Yiyan Fei, Jiong Ma, Ying Chen, Lan Mi
Curcumin (CUR), a natural compound extracted from turmeric, has shown potential as a photosensitizer in photodynamic therapy (PDT). The aim of this work was to enhance the efficacy of CUR by modifying it using titanium dioxide (TiO2) nanoparticles and a cationic polymer called Sofast to create a nanocomposite TiO2-CUR-Sofast (TCS). Compared to unmodified CUR, TCS exhibited a broadening toward longer
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High photoreactivation activities of Rad2 and Rad14 in recovering insecticidal Beauveria bassiana from solar UV damage J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-23 Lei Yu, Si-Yuan Xu, Xin-Cheng Luo, Sheng-Hua Ying, Ming-Guang Feng
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Effects of amber LED on inflammatory and regulatory monocytes and lymphocytes J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-18 Kaline de Brito Sousa, Tainá Caroline dos Santos Malavazzi, Maria Fernanda Setúbal Destro Rodrigues, Tamiris Silva, Lucas Andreo, Alessandro Melo Deana, Fabio Daumas Nunes, Sandra Kalil Bussadori, Raquel Agnelli Mesquita-Ferrari, Kristianne Porta Santos Fernandes
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Glucocorticoid receptor mediated sensitization of colon cancer to photodynamic therapy induced cell death J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-13 Ushasri Chilakamarthi, Namita S. Mahadik, Tithi Bhattacharyya, Palivela Siva Gangadhar, Lingamallu Giribabu, Rajkumar Banerjee
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The effect of photolysis of sodium citrate treated with gold chloride using coloured light on the generation of gold nanoparticles and the repression of WiDr colon cancer cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-10 Chien-Wei Cheng, Shwu-Yuan Lee, Shao-Qi Zhan, Cheng-Liang Huang, Tang-Yu Chen, Jeu-Ming P. Yuann, Shiuh-Tsuen Huang, Chi-Ming Chiu, Ji-Yuan Liang
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Daylight photodynamic inactivation of cattle tick Rhipicephalus microplus by porphyrins: An alternative for the ectoparasite control J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-13 Isabela Castro Pereira Gomes, Lorena Dias Amor Divino, Fernanda Meneses Rodrigues, Cinthya Marques Fortes Fleury, Eli Silveira Alves Ducas, Jaqueline Cristine Desordi, Bernardo Almeida Iglesias, Ricardo Costa Santana, Caio Márcio Oliveira Monteiro, Welber Daniel Zanetti Lopes, Pablo José Gonçalves, Guilherme Rocha Lino Souza
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Low-level Nd:YAG laser inhibiting inflammation and oxidative stress in human gingival fibroblasts via AMPK/SIRT3 axis J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-10 Haizheng Zhang, Chenyi Zhang, Lai Pan, Yifan Chen, Zirui Bian, Yuxuan Yang, Ting Ke, Weilian Sun, Lili Chen, Jingyi Tan
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Evaluation of the cytotoxic and immunomodulatory effects of sonodynamic therapy in human pancreatic cancer spheroids J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-10 Federica Foglietta, Patrizia Panzanelli, Riccardo Pizzo, Marta Giacone, Carlo Della Pepa, Gianni Durando, Loredana Serpe, Roberto Canaparo
Sonodynamic therapy (SDT) exploits the energy generated by ultrasound (US) to activate sound-sensitive drugs (sonosensitizers), leading to the generation of reactive oxygen species (ROS) and cancer cell death. Two-dimensional (2D) and three-dimensional (3D) cultures of human pancreatic cancer BxPC-3 cells were chosen as the models with which to investigate the therapeutic effects of the US-activated
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Influence of photoactivation on tissue response to different dyes used in photodynamic therapy and laser ablation therapy J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-09 Luciano Tavares Angelo Cintra, Cristiane Cantiga-Silva, Henrique Augusto Banci, Flávio Duarte Faria, Nathália Evelyn da Silva Machado, Carolina de Barros Morais Cardoso, Pedro Henrique Chaves de Oliveira, Lucas Rodrigues de Araújo Estrela, Gustavo Sivieri-Araujo, Fabio Luiz Camargo Villela Berbert, Arturo Javier Aranda Garcia, Renato de Toledo Leonardo
Laser ablation therapy (LA) uses Indocyanine Green dye (ICG) which efficiently absorbs laser energy and the increased temperature results in an instantaneous flame that chars tissue and microbes. Photodynamic therapy (PDT) uses different dyes that are activated by light to kill bacteria. This study evaluated the biocompatibility of the dye Curcumin (CUR), Methylene Blue (MB), and Indocyanine Green
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Editorial Board J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-03
Abstract not available
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In vitro photoprotective potential of aryl-sandwiched (thio)semicarbazones against UVA mediated cellular and DNA damage J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2024-01-04 Noor Fatima, Sana Yaqoob, Sobia Rana, Abdul Hameed, Munazza Raza Mirza, Almas Jabeen
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Assessing the efficacy of gutiferone E in photodynamic therapy for oral candidiasis J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-12-24 Luis Fernando Gonçalves Lima, Vítor de Paula Castro, Carmen Magaly Ormeño Álvarez, Sérgio Ricardo Ambrósio, Marcela Aldrovani Rodrigues, Regina Helena Pires
The rise in antifungal resistance and side effects of conventional treatments drive the search for innovative therapies like Photodynamic Therapy (PDT). This study explored the efficacy of PDT mediated by gutiferone, an isolated compound from red propolis, for candidiasis treatment. Multiple evaluation methods were employed, including determining the minimum inhibitory concentration (MIC) via broth
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Cyclometalated Ir(III) theranostic molecular probe enabled mitochondria targeted fluorescence-SERS-guided phototherapy in breast cancer cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-12-21 Chandana Reghukumar, Shanmughan Shamjith, Vishnu Priya Murali, Pilankatta K. Ramya, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar Maiti
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Generalized polarization and time-resolved fluorescence provide evidence for different populations of Laurdan in lipid vesicles J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-12-21 Mihaela Bacalum, Mihai Radu, Silvio Osella, Stefan Knippenberg, Marcel Ameloot
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The therapeutic efficacy of silver loaded rhenium disulfide nanoparticles as a photothermal agent for cancer eradication J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-12-14 Sesha Subramanian Murugan, Won Hur, Seong Eun Son, Han Been Lee, Chang Hyeon Ha, Su Jeong Lee, Se Hwa Cheon, Do Hyeon Kim, Sung Min Jeon, Da Young Choi, Jayachandran Venkatesan, Gi Hun Seong
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BMP4 up-regulated by 630 nm LED irradiation is associated with the amelioration of rheumatoid arthritis J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-12-01 Guoming Du, Mengyue Liu, Yue Qi, Monan Lin, Jiaxin Wu, Wenting Xie, Dandan Ren, Siqi Du, Tong Jia, Fengmin Zhang, Wuqi Song, Hailiang Liu
Rheumatoid arthritis (RA) is caused by inflammatory response of joints with cartilage and damage of synovium and bone erosion. In our previous studies, it has showed that irradiation of 630 nm LED reduce inflammation of synovial fibroblasts and cartilage and bone destruction in RA. However, the key genes and mechanism in ameliorating RA by irradiation of 630 nm LED remains unknown. In this study, human
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Effect of photobiomodulation therapy on TGF-β release from dentin, migration and viability of dental pulp stem cells in regenerative endodontics treatment: An ex vivo study J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-24 Fatemeh Malekpour, Rashin Bahrami, Mahshid Hodjat, Neda Hakimiha, Behnam Bolhari, Aidin Sooratgar, Soheil Niavarzi
Background and aim Regenerative endodontic procedures (REPs) are oriented by the principles of tissue engineering, incorporating dental pulp stem cells (DPSC), crucial growth factors like Transforming growth factor-β (TGF-β1), and scaffolds to facilitate the regeneration of dental pulp tissues. The present study aimed to investigate the effect of photobiomodulation (PBM) therapy, using an 808 nm diode
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Blue-light-driven photoactivity of L-cysteine-modified graphene quantum dots and their antibacterial effects J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-24 Mila Milenković, Gabriele Ciasca, Aurelio Bonasera, Michelangelo Scopelliti, Olivera Marković, Tatjana Verbić, Biljana Todorović Marković, Svetlana Jovanović
The widespread abuse of traditional antibiotics has led to a global rise in antibiotic-resistant bacteria, which give in return unprecedented health risks. Therefore, there is a large and urgent need for the development of new, smart antibacterial agents able to efficiently kill or inhibit bacterial growth. In this study, we investigated the antibacterial activity of S, N-doped Graphene Quantum Dots
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Amplifying bactericidal activity: Surfactant-mediated AgBr thin film coating over two-dimensional vertically aligned ZnO nanorods for dark-light dual mode disinfection J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-20 Pranathi Tata, Ramakrishnan Ganesan, Jayati Ray Dutta
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Exploring the effect of photobiomodulation and gamma visual stimulation induced by 808 nm and visible LED in Alzheimer's disease mouse model J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-23 Hao Xu, Ziyi Luo, Renlong Zhang, Iuliia Golovynska, Yanxia Huang, Soham Samanta, Ting Zhou, Shaowei Li, Bingang Guo, Liwei Liu, Xiaoyu Weng, Jun He, Changrui Liao, Yiping Wang, Tymish Y. Ohulchanskyy, Junle Qu
Although photobiomodulation (PBM) and gamma visual stimulatqion (GVS) have been overwhelmingly explored in the recent time as a possible light stimulation (LS) means of Alzheimer's disease (AD) therapy, their effects have not been assessed at once. In our research, the AD mouse model was stimulated using light with various parameters [continuous wave (PBM) or 40 Hz pulsed visible LED (GVS) or 40 Hz
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Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/PI3K/AKT pathway in osteosarcoma cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-07 Jiali Yang, Hui Jiang, Qiqi Fu, Haokuan Qin, Yinghua Li, Muqing Liu
Blue light photobiomodulation (PBM) has attracted great attention in diminishing proliferation and inducing death of cancer cells recently. Osteosarcoma (OS) primarily occurring in children and adolescents, the limitations of drug resistance and limb salvage make it urgent to develop and identify new adjuvant therapeutic strategies. In this work, we attempted to research the anticancer effects and
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Biomimetic theranostic nanoparticles for effective anticancer therapy and MRI imaging J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-08 Magdalena J. Bigaj-Józefowska, Emerson Coy, Karol Załęski, Tomasz Zalewski, Małgorzata Grabowska, Kaja Jaskot, Patrick Perrigue, Radosław Mrówczyński, Bartosz F. Grześkowiak
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Light spectra manipulation stimulates growth, specialized metabolites and nutritional quality in Anethum graveolens J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-04 Ambika Goswami, Adinpunya Mitra
Light-Emitting Diodes (LED) play a major role in manipulating light spectra that helps in regulating the growth and specialized metabolite synthesis relevant to the plant defence system. In this study, we assessed photosynthetic performance, phytonutrients, and anatomical variations of an aromatic herb Anethum graveolens (also known as dill), grown under various combinations of LED lights viz. red
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Immunofluorescence profiling of collagen subtypes is a predictor of treatment outcomes in pancreatic cancer J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-11-03 Girgis Obaid, Menitte Eroy, Jie Zhao, Shazia Bano, Mari Mino-Kenudson, Tayyaba Hasan
Desmoplasia in pancreatic ductal adenocarcinoma (PDAC) is characterized by elevated levels of tumor collagen. Desmoplasia restricts drug delivery in PDAC, contributes to treatment resistance, and is associated with poor survival outcomes. We have previously shown that photodynamic therapy (PDT)-based treatment remediates desmoplasia in orthotopic PDAC tumors by reducing second harmonic generation signals
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A Eu3+doped functional core-shell nanophosphor as fluorescent biosensor for highly selective and sensitive detection of dsDNA J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-27 Arpita Dwivedi, Monika Srivastava, Amit Srivastava, Abhai Kumar, Rameshwar Nath Chaurasia, S.K. Srivastava
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Hybrid protein-peptide system for the selective pH-dependent binding and photodynamic ablation of cancer cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-26 Anastasiya Yu. Frolova, Alexey A. Pakhomov, Dmitry L. Kakuev, Anna S. Sungurova, Anastasiya A. Dremina, Elizaveta D. Mamontova, Sergey M. Deyev, Vladimir I. Martynov
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Overexpression of SIRT6 regulates NRF2/HO-1 and NF-κB signaling pathways to alleviate UVA-induced photoaging in skin fibroblasts J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-15 Tao Wang, Yonghong Qin, Jianxiong Qiao, Yang Liu, Lerong Wang, Xuanfen Zhang
Skin photoaging, resulting from prolonged exposure to sunlight, especially UVA rays, has been identified as a key contributor to age-related skin degeneration. However, the mechanism by which UVA radiation induces skin cell senescence has not been fully elucidated. In this investigation, bioinformatics technology was employed to identify SIRT6 as the core hub gene involved in the progression of skin
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Tirapazamine combined with photodynamic therapy improves the efficacy of ABZSO nanoparticles on Echinococcosis granulosus via further enhancing “breaking-then-curing” J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-06 Yuehong Gong, Tianjiao Zhou, Wusimanjiang Aimaiti, Yuxia Lin, Yuan Xu, Jianhua Yang, Zhangjian Huang, Hao Wen, Hulin Jiang, Jianhua Wang
Background Photodynamic therapy (PDT) has a promising application prospect in Echinococcus granulosus (Egs), however, the hypoxic environment of Egs and the hypoxia associated with PDT will greatly limit its effects. As a hypoxic-activated pre-chemotherapeutic drug, tirapazamine (TPZ) can be only activated and produce cytotoxicity under hypoxia environment. Albendazole sulfoxide (ABZSO) is the first
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Photoinactivation of Escherichia coli by 405 nm and 450 nm light-emitting diodes: Comparison of continuous wave and pulsed light J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-06 Shijie Huang, Haokuan Qin, Muqing Liu
Background Antimicrobial blue light (ABL) therapy is one of the novel non-antibiotic approaches and recent studies showed the potential of pulsed ABL. Purpose Comparing photoinactivation effect of continuous wave (CW) and pulsed blue light and investigating the impact of varying light parameters. Methods E. coli cells in planktonic were treated with CW and pulsed light (405 nm and 450 nm) at 60 mW/cm2
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Photostability and phototoxicity of graphene quantum dots interacting with red blood cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-11 Tatsiana Kulahava, Nikita Belko, Marina Parkhats, Anastasiya Bahdanava, Sergei Lepeshkevich, Vyacheslav Chizhevsky, Dmitri Mogilevtsev
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Development of light and pH-dual responsive self-quenching theranostic SPION to make EGFR overexpressing micro tumors glow and destroy J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-10 Nihan Verimli, S. İrem Goralı, Beyza Abisoglu, Cem Levent Altan, Bilgesu Onur Sucu, Ersin Karatas, Ahmet Tulek, Cigdem Bayraktaroglu, Mustafa Caglar Beker, S. Sibel Erdem
Drug resistant and undetectable tumors easily escape treatment leading metastases and/or recurrence of the lethal disease. Therefore, it is vital to diagnose and destroy micro tumors using simple yet novel approaches. Here, we present fluorescence-based detection and light-based destruction of cancer cells that are known to be resistant to standard therapies. We developed a superparamagnetic iron oxide
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Unleashing the power of porphyrin photosensitizers: Illuminating breakthroughs in photodynamic therapy J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-10-04 Alibasha Akbar, Syamantak Khan, Tanmay Chatterjee, Mihir Ghosh
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Pre-harvest supplemental LED treatments led to improved postharvest quality of sweet basil leaves J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-22 Ali Ibrahim Sale, Apiradee Uthairatanakij, Natta Laohakunjit, Pongphen Jitareerat, Nattapon Kaisangsri
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Limits of antibacterial activity of triangular silver nanoplates and photothermal enhancement thereof for Bacillus subtilis J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-18 Sarabjot Kaur, Rajneesh Dadwal, Hemraj Nandanwar, Sanjeev Soni
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Amyloid dye pairs as spectral sensors for enhanced detection and differentiation of misfolded proteins J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-16 Anastasiia A. Stepanchuk, Peter K. Stys
Protein misfolding with subsequent formation of cross-β-sheet-rich fibrils is a well-known pathological hallmark of various neurodegenerative conditions, including Alzheimer's disease (AD). Recent evidence suggests that specific protein conformations may be the primary drivers of disease progression, differentiation of which remains a challenge with conventional methods. We have previously described
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Effective transport of aggregated hypericin encapsulated in SBA-15 nanoporous silica particles for photodynamic therapy of cancer cells J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-09 Viktória Pevná, Ľuboš Zauška, Anass Benziane, György Vámosi, Vladimír Girman, Monika Miklóšová, Vladimír Zeleňák, Veronika Huntošová, Miroslav Almáši
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Skin optical properties from 200 to 300 nm support far UV-C skin-safety in vivo J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-04 Daniela F. Zamudio Díaz, Anna Lena Klein, Martin Guttmann, Paula Zwicker, Loris Busch, Marius Kröger, Holger Klose, Sascha Rohn, Johannes Schleusener, Martina C. Meinke
The growing threat of multi-drug resistant pathogens and airborne microbial diseases has highlighted the need to improve or develop novel disinfection methods for clinical environments. Conventional ultraviolet C (UV-C) lamps effectively inactivate microorganisms but are harmful to human skin and eyes upon exposure. The use of new 233 nm far UV-C LEDs as an antiseptic can overcome those limitations
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Advanced theranostic nanoplatforms for hypericin delivery in the cancer treatment J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-01 Flávia Amanda Pedroso de Morais, Rodolfo Bento Balbinot, Amanda Beatriz Kawano Bakoshi, Danielle Lazarin-Bidoia, Katieli da Silva Souza Campanholi, Ranulfo Combuca da Silva Junior, Renato Sonchini Gonçalves, Tânia Ueda-Nakamura, Sueli de Oliveira Silva, Wilker Caetano, Celso Vataru Nakamura
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A re-evaluation of the role of coumarin C460 as a fluorescent Pd(II) sensor J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-09-01 Nika Žurga, Thomas Moragues, Andrew J. deMello
In 2018, Ashwin and co-workers presented a method for the selective and sensitive detection of Pd2+ based on variations in the fluorescence of coumarin (C460). Herein, we re-evaluate the ability of C460 to probe Pd2+ concentration via a systematic reproduction of the experiments reported in the original publication and the performance of additional control experiments. Our analysis indicates that C460
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Unleashing the potential of 5-Aminolevulinic acid: Unveiling a promising target for cancer diagnosis and treatment beyond photodynamic therapy J. Photochem. Photobiol. B Biol. (IF 5.4) Pub Date : 2023-08-24 Sara Sansaloni-Pastor, Norbert Lange
The therapeutic properties of 5-aminolevulinic acid (5-ALA) have been extensively studied for cancer detection and treatment using photodynamic therapy (PDT). When administered externally, 5-ALA is converted to protoporphyrin IX (PpIX) in cancer cells, which generates reactive oxygen species (ROS) upon exposure to light. This process enables targeted cell death induction and cancer detection. Given