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Plasma and serum metabolic analysis of healthy adults shows characteristic profiles by subjects’ sex and age Metabolomics (IF 3.6) Pub Date : 2024-03-16 Rui Xu, Shiqi Zhang, Jieli Li, Jiangjiang Zhu
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Current data processing methods and reporting standards for untargeted analysis of volatile organic compounds using direct mass spectrometry: a systematic review Metabolomics (IF 3.6) Pub Date : 2024-03-16 K Rosenthal, MR Lindley, MA Turner, E Ratcliffe, E Hunsicker
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Perspective: use and reuse of NMR-based metabolomics data: what works and what remains challenging Metabolomics (IF 3.6) Pub Date : 2024-03-13 Goncalo Jorge Gouveia, Thomas Head, Leo L. Cheng, Chaevien S. Clendinen, John R. Cort, Xiuxia Du, Arthur S. Edison, Candace C. Fleischer, Jeffrey Hoch, Nathaniel Mercaldo, Wimal Pathmasiri, Daniel Raftery, Tracey B. Schock, Lloyd W. Sumner, Panteleimon G. Takis, Valérie Copié, Hamid R. Eghbalnia, Robert Powers
Background The National Cancer Institute issued a Request for Information (RFI; NOT-CA-23-007) in October 2022, soliciting input on using and reusing metabolomics data. This RFI aimed to gather input on best practices for metabolomics data storage, management, and use/reuse. Aim of review The nuclear magnetic resonance (NMR) Interest Group within the Metabolomics Association of North America (MANA)
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Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection Metabolomics (IF 3.6) Pub Date : 2024-03-09
Abstract Introduction Studies of gastrointestinal physiology and the gut microbiome often consider the influence of intestinal region on experimental endpoints. However, this same consideration is not often applied to the gut metabolome. Understanding the contribution of gut regionality may be critically important to the rapidly changing metabolic environments, such as during pregnancy. Objectives
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Untargeted NMR-based metabolomics analysis of kidney allograft perfusates identifies a signature of delayed graft function Metabolomics (IF 3.6) Pub Date : 2024-03-09 A. Cirillo, M. Vandermeulen, P. Erpicum, T. Pinto Coelho, N. Meurisse, O. Detry, F. Jouret, P. de Tullio
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Comparisons of different extraction methods and solvents for saliva samples Metabolomics (IF 3.6) Pub Date : 2024-03-09 Lingli Fang, Qiming Zhai, Hua Zhang, Ping Ji, Chang Chen, Hongmei Zhang
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Clinical advances in analytical profiling of signature lipids: implications for severe non-communicable and neurodegenerative diseases Metabolomics (IF 3.6) Pub Date : 2024-03-08
Abstract Background Lipids play key roles in numerous biological processes, including energy storage, cell membrane structure, signaling, immune responses, and homeostasis, making lipidomics a vital branch of metabolomics that analyzes and characterizes a wide range of lipid classes. Addressing the complex etiology, age-related risk, progression, inflammation, and research overlap in conditions like
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Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock Metabolomics (IF 3.6) Pub Date : 2024-03-06 Robert S. Rogers, Rohit Sharma, Hardik B. Shah, Owen S. Skinner, Xiaoyan A. Guo, Apekshya Panda, Rahul Gupta, Timothy J. Durham, Kelsey B. Shaughnessy, Jared R. Mayers, Kathryn A. Hibbert, Rebecca M. Baron, B. Taylor Thompson, Vamsi K. Mootha
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Dietary habits and plasma lipid concentrations in a general Japanese population Metabolomics (IF 3.6) Pub Date : 2024-03-05 Mitsuharu Sato, Eiji Hishinuma, Naomi Matsukawa, Yoshiko Shima, Daisuke Saigusa, Ikuko N. Motoike, Mana Kogure, Naoki Nakaya, Atsushi Hozawa, Shinichi Kuriyama, Masayuki Yamamoto, Seizo Koshiba, Kengo Kinoshita
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Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia Metabolomics (IF 3.6) Pub Date : 2024-03-05 Ilona den Hartog, Laura B. Zwep, Jacqueline J. Meulman, Thomas Hankemeier, Ewoudt M. W. van de Garde, J. G. Coen van Hasselt
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An exploratory investigation of the CSF metabolic profile of HIV in a South African paediatric cohort using GCxGC-TOF/MS Metabolomics (IF 3.6) Pub Date : 2024-03-01
Abstract Introduction Because cerebrospinal fluid (CSF) samples are difficult to obtain for paediatric HIV, few studies have attempted to profile neurometabolic dysregulation. Aim and objective The aim of this exploratory study was to profile the neurometabolic state of CSF from a South African paediatric cohort using GCxGC-TOF/MS. The study included 54 paediatric cases (< 12 years), 42 HIV-negative
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Disrupted Tuzzerella abundance and impaired l-glutamine levels induce Treg accumulation in ovarian endometriosis: a comprehensive multi-omics analysis Metabolomics (IF 3.6) Pub Date : 2024-02-29 Yichen Chen, Lingfang Ye, Jue Zhu, Liang Chen, Huan Chen, Yuhui Sun, Yishen Rong, Jing Zhang
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Untargeted metabolomic, and proteomic analysis identifies metabolic biomarkers and pathway alterations in individuals with 22q11.2 deletion syndrome Metabolomics (IF 3.6) Pub Date : 2024-02-28 Marwa Zafarullah, Kathleen Angkustsiri, Austin Quach, Seungjun Yeo, Blythe P. Durbin-Johnson, Heather Bowling, Flora Tassone
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Discovery of metabolite biomarkers for odontogenic keratocysts Metabolomics (IF 3.6) Pub Date : 2024-02-28 Shuai Wang, Liyuan Yu, Lin Chen, Tao Zeng, Xianghui Xing, Zheng Wei
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Identification of glucose-independent and reversible metabolic pathways associated with anti-proliferative effect of metformin in liver cancer cells Metabolomics (IF 3.6) Pub Date : 2024-02-27 Sk Ramiz Islam, Soumen Kanti Manna
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Associations of the placental metabolome with immune maturation up to one year of age in the Swedish NICE-cohort Metabolomics (IF 3.6) Pub Date : 2024-02-26 Olle Hartvigsson, Malin Barman, Hardis Rabe, Anna Sandin, Agnes E Wold, Carl Brunius, Ann-Sofie Sandberg
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Investigation into the role of phenolic compounds in the protection of citrus against Phyllosticta citricarpa Metabolomics (IF 3.6) Pub Date : 2024-02-26
Abstract Introduction The use of chemical fungicides to combat disease has made a substantial contribution to food quality and security. Nonetheless, their applications have been limited due to environmental and health concerns, unaffordability, and the fact that pathogens have acquired resistance to some of these fungicides. Alternative eco-friendly and safe control methods should be explored. The
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Metabolomics approach for phenolic compounds profiling of soursop (Annona muricata L.) fruit during postharvest storage Metabolomics (IF 3.6) Pub Date : 2024-02-25 Verónica Alhelí Ochoa-Jiménez, Guillermo Berumen-Varela, Iza Fernanda Pérez-Ramírez, Rosendo Balois-Morales, Alejandro Rubio-Melgarejo, Pedro Ulises Bautista-Rosales
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First comprehensive untargeted metabolomics study of suramin-treated Trypanosoma brucei: an integrated data analysis workflow from multifactor data modelling to functional analysis Metabolomics (IF 3.6) Pub Date : 2024-02-23 Fanta Fall, Lucia Mamede, Madeline Vast, Pascal De Tullio, Marie-Pierre Hayette, Paul A. M. Michels, Michel Frédérich, Bernadette Govaerts, Joëlle Quetin-Leclercq
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Toxicometabolomics-based cardiotoxicity evaluation of Thiazolidinedione exposure in human-derived cardiomyocytes Metabolomics (IF 3.6) Pub Date : 2024-02-23 Abdullah Al Sultan, Zahra Rattray, Nicholas J. W. Rattray
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Evaluation of normalization strategies for GC-based metabolomics Metabolomics (IF 3.6) Pub Date : 2024-02-12 Seo Lin Nam, Ryland T. Giebelhaus, Kieran S. Tarazona Carrillo, A. Paulina de la Mata, James J. Harynuk
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Circadian rhythm in turbot (Scophthalmus maximus): daily variation of blood metabolites in recirculating aquaculture systems Metabolomics (IF 3.6) Pub Date : 2024-02-12 J. Petereit, G. Lannig, B. Baßmann, C. Bock, B. H. Buck
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Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics Metabolomics (IF 3.6) Pub Date : 2024-02-12
Abstract Background Quality assurance (QA) and quality control (QC) practices are key tenets that facilitate study and data quality across all applications of untargeted metabolomics. These important practices will strengthen this field and accelerate its success. The Best Practices Working Group (WG) within the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) focuses on community
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Exploration of differential responses to FODMAPs and gluten in people with irritable bowel syndrome- a double-blind randomized cross-over challenge study Metabolomics (IF 3.6) Pub Date : 2024-02-12 Elise Nordin, Rikard Landberg, Per M. Hellström, Carl Brunius
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Induced responses to the wheat pathogen: Tan Spot—(Pyrenophora tritici-repentis) in wheat (Triticum aestivum) focus on changes in defence associated and sugar metabolism Metabolomics (IF 3.6) Pub Date : 2024-01-31 Larissa Carvalho Ferreira, Flavio Martins Santana, Sandra Maria Mansur Scagliusi, Manfred Beckmann, Luis A. J. Mur
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Urine and serum metabolomic analysis of endometrial cancer diagnosis and classification based on ultra-performance liquid chromatography mass spectrometry Metabolomics (IF 3.6) Pub Date : 2024-01-28 Junyu Chen, Hezhen Lu, Dongyan Cao, Jiameng Sun, Feng Qi, Xiaoyan Liu, Jiaqi Liu, Jiaxin Yang, Mei Yu, Huimei Zhou, Ninghai Cheng, Jinhui Wang, Ying Zhang, Peng Peng, Tao Wang, Keng Shen, Wei Sun
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Challenges and perspectives for naming lipids in the context of lipidomics Metabolomics (IF 3.6) Pub Date : 2024-01-24 Michael Witting, Adnan Malik, Andrew Leach, Alan Bridge, Lucila Aimo, Matthew J. Conroy, Valerie B. O’Donnell, Nils Hoffmann, Dominik Kopczynski, Franck Giacomoni, Nils Paulhe, Amaury Cazenave Gassiot, Nathalie Poupin, Fabien Jourdan, Justine Bertrand-Michel
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Metabolomic data presents challenges for epidemiological meta-analysis: a case study of childhood body mass index from the ECHO consortium Metabolomics (IF 3.6) Pub Date : 2024-01-24 Nicole Prince, Donghai Liang, Youran Tan, Akram Alshawabkeh, Elizabeth Esther Angel, Stefanie A. Busgang, Su H. Chu, José F. Cordero, Paul Curtin, Anne L. Dunlop, Diane Gilbert-Diamond, Cecilia Giulivi, Anne G. Hoen, Margaret R. Karagas, David Kirchner, Augusto A. Litonjua, Justin Manjourides, Susan McRitchie, John D. Meeker, Wimal Pathmasiri, Wei Perng, Rebecca J. Schmidt, Deborah J. Watkins, Scott
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Metabolomic profiling of human bladder tissue extracts Metabolomics (IF 3.6) Pub Date : 2024-01-24 Krzysztof Ossoliński, Tomasz Ruman, Valérie Copié, Brian P. Tripet, Artur Kołodziej, Aneta Płaza-Altamer, Anna Ossolińska, Tadeusz Ossoliński, Zuzanna Krupa, Joanna Nizioł
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Classifying patients with psoriatic arthritis according to their disease activity status using serum metabolites and machine learning Metabolomics (IF 3.6) Pub Date : 2024-01-24
Abstract Introduction Psoriatic arthritis (PsA) is a heterogeneous inflammatory arthritis, affecting approximately a quarter of patients with psoriasis. Accurate assessment of disease activity is difficult. There are currently no clinically validated biomarkers to stratify PsA patients based on their disease activity, which is important for improving clinical management. Objectives To identify metabolites
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Plasma lipidomic profiling reveals six candidate biomarkers for the prediction of incident stroke in patients with hypertension Metabolomics (IF 3.6) Pub Date : 2024-01-05 Jingjing Zeng, Ruijie Zhang, Tian Zhao, Han Wang, Liyuan Han, Liyuan Pu, Yannan Jiang, Shan Xu, Huiming Ren, Changyi Wang
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Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study Metabolomics (IF 3.6) Pub Date : 2024-01-05 Jonas Ellegaard Nielsen, Trygve Andreassen, Charlotte Held Gotfredsen, Dorte Aalund Olsen, Karsten Vestergaard, Jonna Skov Madsen, Søren Risom Kristensen, Shona Pedersen
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Distinct emissions of biogenic volatile organic compounds from temperate benthic taxa Metabolomics (IF 3.6) Pub Date : 2023-12-22 Axel Olander, Jean-Baptiste Raina, Caitlin A. Lawson, Natasha Bartels, Maiken Ueland, David J. Suggett
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Extended automated quantification algorithm (AQuA) for targeted 1H NMR metabolomics of highly complex samples: application to plant root exudates Metabolomics (IF 3.6) Pub Date : 2023-12-23 Elin Alexandersson, Corine Sandström, Johan Meijer, Gustav Nestor, Anders Broberg, Hanna E. Röhnisch
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A lipidomic and metabolomic signature of a very low-carbohydrate high-fat diet and high-intensity interval training: an additional analysis of a randomized controlled clinical trial Metabolomics (IF 3.6) Pub Date : 2023-12-23 Lukas Cipryan, Vit Kosek, Carlos J. García, Tomas Dostal, Kamila Bechynska, Jana Hajslova, Peter Hofmann
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Performance evaluate of different chemometrics formalisms used for prostate cancer diagnosis by NMR-based metabolomics Metabolomics (IF 3.6) Pub Date : 2023-12-21 Márcio Felipe Oliveira, Moacir Cavalcante de Albuquerque Neto, Thiago Siqueira Leite, Paulo André Araújo Alves, Salvador Vilar Correia Lima, Ricardo Oliveira Silva
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Improving quality of analysis by suppression of unwanted signals through band-selective excitation in NMR spectroscopy for metabolomics studies Metabolomics (IF 3.6) Pub Date : 2023-12-19 Upendra Singh, Ruba Al-Nemi, Fatimah Alahmari, Abdul-Hamid Emwas, Mariusz Jaremko
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Maternal and newborn metabolomic changes associated with urinary polycyclic aromatic hydrocarbon metabolite concentrations at delivery: an untargeted approach Metabolomics (IF 3.6) Pub Date : 2023-12-14 Jagadeesh Puvvula, Kathrine E. Manz, Joseph M. Braun, Kurt D. Pennell, Emily A. DeFranco, Shuk-Mei Ho, Yuet-Kin Leung, Shouxiong Huang, Ann M. Vuong, Stephani S. Kim, Zana P. Percy, Priyanka Bhashyam, Raymund Lee, Dean P. Jones, Vilinh Tran, Dasom V. Kim, Aimin Chen
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Discrimination of different feed additives and poly-herbal formulations based on their untargeted phytochemical profiles Metabolomics (IF 3.6) Pub Date : 2023-12-11 Gabriele Rocchetti, Marco Lapris, Gokhan Zengin, Francesco Masoero, Antonio Gallo
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Comparison of nocturnal and diurnal metabolomes of rose flowers and leaves Metabolomics (IF 3.6) Pub Date : 2023-12-08 Julie Zumsteg, Elodie Bossard, Lorène Gourguillon, Claire Villette, Dimitri Heintz
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Non-targeted LC–MS/MS metabolomic profiling of human plasma uncovers a novel Mediterranean diet biomarker panel Metabolomics (IF 3.6) Pub Date : 2023-12-08 Shirin Macias, Ali Yilmaz, Joseph Kirma, Sarah E. Moore, Jayne V. Woodside, Stewart F. Graham, Brian D. Green
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A new statistical workflow (R-packages based) to investigate associations between one variable of interest and the metabolome Metabolomics (IF 3.6) Pub Date : 2023-11-30 Paola G. Ferrario, Achim Bub, Lara Frommherz, Ralf Krüger, Manuela J. Rist, Bernhard Watzl
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Machine learning for predicting diabetic metabolism in the Indian population using polar metabolomic and lipidomic features Metabolomics (IF 3.6) Pub Date : 2023-11-28 Nikita Jain, Bhaumik Patel, Manjesh Hanawal, Anurag R. Lila, Saba Memon, Tushar Bandgar, Ashutosh Kumar
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Using metabolomics to understand stress responses in Lactic Acid Bacteria and their applications in the food industry Metabolomics (IF 3.6) Pub Date : 2023-11-24 Elvina Parlindungan, Oliver A. H. Jones
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Acute changes in the metabolome following resistance exercise combined with intake of different protein sources (cricket, pea, whey) Metabolomics (IF 3.6) Pub Date : 2023-11-24 Sofie Kaas Lanng, Mikkel Oxfeldt, Frank Ted Johansen, Jeyanthini Risikesan, Mette Hansen, Hanne Christine Bertram
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High fat diet reveals sex-specific fecal and liver metabolic alterations in C57BL/6J obese mice Metabolomics (IF 3.6) Pub Date : 2023-11-24 Bo Wang, Vidya Jadhav, Anuoluwapo Odelade, Evelyn Chang, Alex Chang, Scott H. Harrison, Antoinette M. Maldonado-Devincci, Joseph L. Graves, Jian Han
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Maternal exposure to polystyrene nanoplastics alters fetal brain metabolism in mice Metabolomics (IF 3.6) Pub Date : 2023-11-21 Grace V. Mercer, Nikita E. Harvey, Katherine L. Steeves, Céline M. Schneider, John G. Sled, Christopher K. Macgowan, Ahmet A. Baschat, John C. Kingdom, André J. Simpson, Myrna J. Simpson, Karl J. Jobst, Lindsay S. Cahill
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Highlights of three metabolites HDL and reduction in blood pressure values after dietary fiber supplementation in overweight and obese normotensive women: a metabolomic study Metabolomics (IF 3.6) Pub Date : 2023-11-17 Cássia Surama Oliveira da Silva, Mussara Gomes Cavalcanti Alves Monteiro, Carla Patricia Novaes dos Santos Fechine, Josean Fechine Tavares, Augusto Lopes Souto, Rafaella Cristhine Pordeus Luna, Flávia Cristina Fernandes Pimenta, Ana Herminia Andrade e Silva, Alcides da Silva Diniz, Celso Costa da Silva Júnior, Caio César Ferreira Alverga, Sócrates Golzio dos Santos, Darlene Camati Persuhn, Maria José
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Bone marrow plasma metabonomics of idiopathic acquired aplastic anemia patients using 1H nuclear magnetic resonance spectroscopy Metabolomics (IF 3.6) Pub Date : 2023-11-17 Jyotika Srivastava, Rimjhim Trivedi, Pragati Saxena, Sanjeev Yadav, Ruchi Gupta, Soniya Nityanand, Dinesh Kumar, Chandra P. Chaturvedi
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Metabolomics 2022 workshop report: state of QA/QC best practices in LC–MS-based untargeted metabolomics, informed through mQACC community engagement initiatives Metabolomics (IF 3.6) Pub Date : 2023-11-08 Warwick B. Dunn, Julia Kuligowski, Matthew Lewis, Jonathan D. Mosley, Tracey Schock, Candice Ulmer Holland, Krista A. Zanetti, Dajana Vuckovic
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Clinical metabolomics by NMR revealed serum metabolic signatures for differentiating sarcoidosis from tuberculosis Metabolomics (IF 3.6) Pub Date : 2023-11-08 Mohit Kumar Rai, Sachin Yadav, Avinash Jain, kritika Singh, Amit Kumar, Ritu Raj, Durgesh Dubey, Harshit Singh, Anupam Guleria, Saurabh Chaturvedi, Abdul Rahman Khan, Alok Nath, Durga Prasanna Misra, Vikas Agarwal, Dinesh Kumar
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Identification of potential quality markers in Indonesia’s Arabica specialty coffee using GC/MS-based metabolomics approach Metabolomics (IF 3.6) Pub Date : 2023-10-25 Fitri Amalia, Tomoya Irifune, Tetsuji Takegami, Yusianto, Ucu Sumirat, Sastia Prama Putri, Eiichiro Fukusaki
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Metabolomic profiling of preterm birth in pregnant women living with HIV Metabolomics (IF 3.6) Pub Date : 2023-10-25 Nicole H. Tobin, Aisling Murphy, Fan Li, Sean S. Brummel, Mary Glenn Fowler, James A. Mcintyre, Judith S. Currier, Tsungai Chipato, Patricia M. Flynn, Luis A. Gadama, Friday Saidi, Clemensia Nakabiito, Brian J. Koos, Grace M. Aldrovandi
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Characterization of phytochemicals from twisted-leaf garlic (Allium obliquum L.) using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry Metabolomics (IF 3.6) Pub Date : 2023-10-21 Christoph Böttcher, Linh T. Bach, Melanie Stürtz, Hartwig Schulz
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Quantitative LC–MS study of compounds found predictive of COVID-19 severity and outcome Metabolomics (IF 3.6) Pub Date : 2023-10-18 Ivayla Roberts, Marina Wright Muelas, Joseph M. Taylor, Andrew S. Davison, Catherine L. Winder, Royston Goodacre, Douglas B. Kell
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Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates Metabolomics (IF 3.6) Pub Date : 2023-10-19 Jinchun Sun, Neetu Dahiya, Thomas Schmitt, Caitlin Stewart, John Anderson, Scott MacGregor, Michelle Maclean, Richard D. Beger, Chintamani D. Atreya
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GC-MS based comparative metabolomic analysis of human cancellous bone reveals the critical role of linoleic acid metabolism in femur head necrosis Metabolomics (IF 3.6) Pub Date : 2023-09-30 Weiwen Zhu, Rui Wang, Zhijian Yang, Xuming Luo, Baoxi Yu, Jian Zhang, Ming Fu
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Correlations for untargeted GC × GC-HRTOF-MS metabolomics of colorectal cancer Metabolomics (IF 3.6) Pub Date : 2023-09-23 Nicolas Di Giovanni, Marie-Alice Meuwis, Edouard Louis, Jean-François Focant
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Staging of colorectal cancer using lipid biomarkers and machine learning Metabolomics (IF 3.6) Pub Date : 2023-09-20 Sanduru Thamarai Krishnan, David Winkler, Darren Creek, Dovile Anderson, Chandra Kirana, Guy J Maddern, Kevin Fenix, Ehud Hauben, David Rudd, Nicolas Hans Voelcker
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Multi-tissue transcriptomic and serum metabolomic assessment reveals systemic implications of acute ozone-induced stress response in male Wistar Kyoto rats Metabolomics (IF 3.6) Pub Date : 2023-09-10 Thomas W. Jackson, John S. House, Andres R. Henriquez, Mette C. Schladweiler, Kimberly MP Jackson, Anna A. Fisher, Sam J. Snow, Devin I. Alewel, Allison A. Motsinger-Reif, Urmila P. Kodavanti