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[Front cover] IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-12-30
Presents the front cover for this issue of the publication.
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IEEE Transactions on NanoBioscience publication information IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-12-30
Provides a listing of current staff, committee members and society officers.
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Table of contents IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-12-31
Presents the table of contents for this issue of the publication.
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Miniaturized Electrochemiluminescence Platform With Laser-Induced Graphene Electrodes for Multiple Biosensing IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-11-09 Manish Bhaiyya; Prakash Rewatkar; Mary Salve; Prasant Kumar Pattnaik; Sanket Goel
The present work demonstrates a miniaturized 3D printed Electrochemiluminescence (ECL) sensing platform with Laser-Induced Graphene (LIG) based Open Bipolar Electrodes (OBEs). To fabricate OBEs, polyimide (PI) substrate has been used as it provides properties like low-cost fabrication, high selectivity, great stability, easy reproducibility, cost-effectiveness and rapid prototyping. Moreover, graphene
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On Mathematical Analysis of Active Drug Transport Coupled With Flow-Induced Diffusion in Blood Vessels IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-11-17 Hamidreza Arjmandi; Mohammad Zoofaghari; Seyed Vahid Rouzegar; Mladen Veletić; Ilangko Balasingham
Blood vessels are flow-induced diffusive molecular channels equipped with transport mechanisms across their walls for conveying substances between the organs in the body. Mathematical modeling of the blood vessel as a molecular transport channel can be used for the characterization of the underlying processes and higher-level functions in the circulatory system. Besides, the mathematical model can
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IEEE Transactions on NanoBioscience information for authors IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-12-30
Provides instructions and guidelines to prospective authors who wish to submit manuscripts.
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IoT-Enabled Fluorescence Sensor for Quantitative KET Detection and Anti-Drug Situational Awareness IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-20 Jiuchuan Guo; Shulin Tian; Ke Liu; Jinhong Guo
Recently, drug abuse has become a worldwide concern. Among varieties of drugs, KET is found to be favorite in drug addicts, especially teenagers, for recreational purposes. KET is a kind of analgesic and anesthetic drug which can induce hallucinogenic and dissociative effects after high-dose abuse. Hence, it is critical to develop a rapid and sensitive detection method for strict drug control. In this
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Investigation of the Effect of Channel Structure and Flow Rate on On-Chip Bacterial Lysis IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-15 Araz Norouz Dizaji; Yasin Ozturk; Hamed Ghorbanpoor; Ahmet Cetak; Iremnur Akcakoca; Tanil Kocagoz; Huseyin Avci; Damion Corrigan; Fatma Doğan Güzel
Successful lysis of cells/microorganisms is a key step in the sample preparation in fields like molecular biology, bioengineering, and biomedical engineering. This study therefore aims to investigate the lysis of bacteria on-chip and its dependence on both microfluidic channel structure and flow rate. Effects of temperature on lysis on-chip were also investigated. To perform these investigations, three
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Compilation of a Coupled Hyper-Chaotic Lorenz System Based on DNA Strand Displacement Reaction Network IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-15 Chengye Zou; Qiang Zhang; Xiaopeng Wei
Ideal formal chemical reaction network is an effective programming language to design complex system dynamical behavior. In this article, a coupled hyper-chaotic Lorenz system can be described by the ordinary differential equations of an ideal formal reaction network, which is constructed by catalysis, annihilation and adjust reaction modules, where the variables of system are represented by the difference
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Heterogeneous Idealization of Ion Channel Recordings – Open Channel Noise IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-14 Florian Pein; Annika Bartsch; Claudia Steinem; Axel Munk
We propose a new model-free segmentation method for idealizing ion channel recordings. This method is designed to deal with heterogeneity of measurement errors. This in particular applies to open channel noise which, in general, is particularly difficult to cope with for model-free approaches. Our methodology is able to deal with lowpass filtered data which provides a further computational challenge
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Radiosensitizing and Phototherapeutic Effects of AuNPs are Mediated by Differential Noxa and Bim Gene Expression in MCF-7 Breast Cancer Cell Line IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-05 Sameh Nakhla; Ayman Rahawy; Mohamed Abd El Salam; Thana Shalaby; Mohamed Zaghloul; Eman El-Abd
To compare the apoptotic efficiency of AuNPs, ionizing and non-ionizing radiotherapy, phototherapy, and AuNPs-ionizing-radiotherapy), MCF-7 cells were used as a model for luminal B subtypes of breast carcinoma. A mixture of AuNPs [66% of Au-nanospheres (AuNSs) and 34% of Au-nanorods (AuNRs)] was synthesized and characterized by optical spectroscopy, zeta potential, and transmission electron microscopy
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Front cover IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-30
Presents the front cover for this issue of the publication.
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IEEE Transactions on NanoBioscience publication information IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-30
Presents a listing of the editorial board, board of governors, current staff, committee members, and/or society editors for this issue of the publication.
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Table of contents IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-30
Presents the table of contents for this issue of the publication.
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Modelling the Effective Conductance Drop due to a Particle in a Solid State Nanopore Towards Optimized Design. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-08-11 N Das,G D Ropmay,A M Joseph,C RoyChaudhuri
An understanding of the current change in a solid state nanopore due to particle movement or capture is crucial for improvement of nanopore based sensing technologies. For lower aspect ratio pores, which are gaining importance due to their high sensitivity, there is interplay between access and pore resistance and the existing theories for computation of access resistance cannot explain most of the
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dMole: A Novel Transreceiver for Mobile Molecular Communication using Robust Differential Detection Techniques. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-08-07 Amit K Shrivastava,Debanjan Das,Rajarshi Mahapatra,Saraju P Mohanty
This paper proposes two differential detection techniques for signal detection in mobile molecular communication (MMC) for targeted drug delivery (TDD) application. In MMC, a nano-transmitter and a nano-receiver are considered to be in Brownian motion in an extracellular fluid medium. Transmitter uses calcium molecules to communicate with the receiver. Detection is performed using concentration difference
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IEEE Transactions on NanoBioscience information for authors IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-30
These instructions give guidelines for preparing papers for this publication. Presents information for authors publishing in this journal.
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Biogenic Synthesis of Zinc Oxide Nanoparticles by Bryophyllum pinnatum and its Acute Oral Toxicity Evaluation in Wistar Rats. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-08-03 Abhilash D Jadhao,Sudhir Shende,Pramod Ingle,Aniket Gade,Sunil W Hajare,Ranjit S Ingole
The evaluation of toxic effects of nanoparticles (NPs) has become an important aspect of Nanotechnology research in the 21st century. The present investigation deals with the green synthesis of biogenic zinc oxide nanoparticles (ZnO-NPs) using Bryophyllum pinnatum leaves, their characterization and evaluation of acute oral toxicity in Wistar rats. The characterization of synthesized ZnO-NPs revealed
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Automatic In Situ Synthesis System for Polypeptide Biochip Based on Microfluidic Mixer IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-10-02 Huanhuan Shi; Kaixuan Nie; Bo Dong; Mengqiu Long; Zhengchun Liu
Biochips have become a sophisticated analytical device in the fields of biochemical sensing and genetic analysis. However, the cumbersome preparation process and the high production cost limit the versatility of its application. Herein, we have developed an automated synthesis system for in situ preparation of biochip with peptide backbone based on the microfluidic mixer and micro reaction chamber
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Real Time Sensing of Soil Potassium Levels Using Zinc Oxide-Multiwall Carbon Nanotube-Based Sensors IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-30 A. Akshaya Kumar; S. K. Naveen Kumar; Renny Edwin Fernandez
There is a significant interest in the detection and monitoring of nutrient levels in agriculture farms. In this article, we report the fabrication of Zinc oxide (ZnO) modified multi-walled Carbon nanotube (F-MWCNT) sensor specifically developed for soil nutrient sensing. A thin layer of Valinomycin membrane was grown on the top of the F-MWCNT/ZnO nanocomposite active layer. The resulting composite
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Homeostasis Tissue-like P Systems. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-22 Yueguo Luo,Yuzhen Zhao,Changchuan Chen
Tissue P systems provide distributed parallel devices inspired by actual biological reality, where communication rules are used for object exchange between cells (or between cells and the environment). In such systems, the environment continuously provides energy to cells, so the cells are very dependent on the objects in the environment. In biology, there is a mechanism called homeostasis, that is
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Fabrication and pH-sensitivity Analysis of MOS-HEMT Dimensional Variants for Biosensing Applications. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-14 Arathy Vargehse,Chinnamuthan Periasamy,Lava Bhargava
This work reports the fabrication, characterization and testing for pH sensitivity of dielectric modulated MOS-HEMT(Metal oxide semiconductor- high electron mobility transistor) devices for bio-sensing applications. The primary aim here is to develop high sensing devices for bio-detections. The oxide based gate area is used in ensuring the device performance through pH detection done prior to packaging
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An Enhanced Protein Fold Recognition for Low Similarity Datasets using Convolutional and Skip-Gram Features with Deep Neural Network. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-07 Sanjay Bankapur,Nagamma Patil
The protein fold recognition is one of the important tasks of structural biology, which helps in addressing further challenges like predicting the protein tertiary structures and its functions. Many machine learning works are published to identify the protein folds effectively. However, very few works have reported the fold recognition accuracy above 80% on benchmark datasets. In this study, an effective
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Inbuilt tendency of the eIF2 regulatory system to counteract uncertainties. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-07 Mohammad Farhan Khan,Sarah K Spurgeon,Xing-Gang Yan,Muaffaq M Nofal,Rami Al-Hmouz
Eukaryotic initiation factor 2 (eIF2) plays a fundamental role in the regulation of protein synthesis. Investigations have revealed that the regulation of eIF2 is robust against intrinsic uncertainties and is able to efficiently counteract them. The robustness properties of the eIF2 pathway against intrinsic disturbances is also well known. However the reasons for this ability to counteract stresses
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Information Rates of Controlled Protein Interactions Using Terahertz Communication. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-09-04 Hadeel Elayan,Andrew W Eckford,Raviraj Adve
In this work, we present a paradigm bridging electromagnetic (EM) and molecular communication through a stimuli-responsive intra-body model. It has been established that protein molecules, which play a key role in governing cell behavior, can be selectively stimulated using Terahertz (THz) band frequencies. By triggering protein vibrational modes using THz waves, we induce changes in protein conformation
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Front cover IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-30
Presents the front cover for this issue of the publication.
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IEEE Transactions on NanoBioscience publication information IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-30
Presents a listing of the editorial board, board of governors, current staff, committee members, and/or society editors for this issue of the publication.
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Table of contents IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-30
Presents the table of contents for this issue of the publication.
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Two-Ply Carbon Nanotube Fiber-Typed Enzymatic Biofuel Cell Implanted in Mice. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-18 Dong Yeop Lee,Ji-Hyun Yun,Young Bin Park,Jae Sang Hyeon,Yongwoo Jang,Young-Bong Choi,Hyug-Han Kim,Tong Mook Kang,Raquel Ovalle,Ray H Baughman,Sung Min Kim,Chang Won Kee,Seon Jeong Kim
Implantable devices have emerged as a promising industry. It is inevitable that these devices will require a power source to operate in vivo . Thus, to power implantable medical devices, biofuel cells (BFCs) that generate electricity using glucose without an external power supply have been considered. Although implantable BFCs have been developed for application in vivo , they are limited by their
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New Approach for Making Standard the Development of Biosensing Devices by a Modular Multi-Purpose Design. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-18 Abuduwaili Tuoheti,Simone Aiassa,Francesca Criscuolo,Francesca Stradolini,Ioulia Tzouvadaki,Sandro Carrara,Danilo Demarchi
The fast widening of biosensing applications, such as healthcare, drug delivery, food, and military industries, is increasing the need for generality and compatibility among different sensors. To address this challenge, we present here an innovative approach for the fast development of new electronic biosensing systems, linking a custom-designed front-end with a multi-purpose system. We envision an
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On Gradient Descent Optimization in Diffusion-Advection Based 3-D Molecular Cooperative Communication. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-21 Lokendra Chouhan,Neeraj Varshney,Prabhat Kumar Sharma
This work considers a cooperative communication system in 3-D fluid medium in which the flow of molecules is supported by the drift and the diffusion phenomena. To enhance the system performance, the equal gain combining is used at the destination nanomachine (DN) where the molecular signals arriving from the direct and the cooperative paths are combined together by employing equal weights. Using the
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Modeling of Modulated Exosome Release From Differentiated Induced Neural Stem Cells for Targeted Drug Delivery. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-06 Mladen Veletic,Michael Taynnan Barros,Hamidreza Arjmandi,Sasitharan Balasubramaniam,Ilangko Balasingham
A novel implantable and externally controllable stem-cell-based platform for the treatment of Glioblastoma brain cancer has been proposed to bring hope to patients who suffer from this devastating cancer type. Induced Neural Stem Cells (iNSCs), known to have potent therapeutic effects through exosomes-based molecular communication, play a pivotal role in this platform. Transplanted iNSCs demonstrate
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Detection of Collagen-IV Using Highly Reflective Metal Nanoparticles-Immobilized Photosensitive Optical Fiber-Based MZI Structure. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-29 Brajesh Kumar Kaushik,Lokendra Singh,Ragini Singh,Guo Zhu,Bingyuan Zhang,Qinglin Wang,Santosh Kumar
In this work, a photosensitive (PS) optical fiber-based Mach-Zehnder interferometer (MZI) structure is developed to diagnose the presence of collagen-IV in human bodies. The MZI is fabricated by sequentially splicing the single mode-multimode-photosensitive-multimode-single mode (SMPMS) fiber segments. The sensing region in MZI structure is created by partially removing the cladding of photosensitive
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Systematic Review and Meta-Analysis of the Efficacy of Nanoscale Materials Against Coronaviruses-Possible Potential Antiviral Agents for SARS-CoV-2. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-25 Fahimeh Alizadeh,Alireza Khodavandi
The available antiviral agents and their potential for the management of coronavirus disease 2019 (COVID-19) outbreak are important interventions. A systematic review and meta-analysis was performed to summarize the available evidence on the efficacy of nanoscale materials against coronaviruses in vitro and in animal models. PubMed, Scopus and Wiley Online Library databases were searched up to 4 March
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IEEE BIBM 2019 Special Issue IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-30 Xiaohua Hu
Bioinformatics and biomedicine research is fundamental to our understanding of complex biological systems, impacting the science and technology of fields ranging from agricultural and environmental sciences to pharmaceutical and medical sciences. This type of research requires close collaboration among multidisciplinary teams of researchers in computer science, statistics, physics, engineering, life
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An Application of Random Walk Resampling to Phylogenetic HMM Inference and Learning. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-08 Wei Wang,Qiqige Wuyun,Kevin J Liu
Statistical resampling methods are widely used for confidence interval placement and as a data perturbation technique for statistical inference and learning. An important assumption of popular resampling methods such as the standard bootstrap is that input observations are identically and independently distributed (i.i.d.). However, within the area of computational biology and bioinformatics, many
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A Knowledge-Driven Network-Based Analytical Framework for the Identification of Rumen Metabolites. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-30 Mengyuan Wang,Haiying Wang,Huiru Zheng,Richard Dewhurst,Rainer Roehe
Metabolites are the final production of biochemical reactions in the rumen micro-ecological system and are very sensitive to changes in rumen microbes. Nuclear magnetic resonance (NMR) spectroscopy could both identify and quantify the metabolic composition of the ruminal fluid, which reflects the interaction between rumen microbes and diet. The main challenge of untargeted metabolomics is the compound
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An Improved Classification Model for Depression Detection Using EEG and Eye Tracking Data. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-27 Jing Zhu,Zihan Wang,Tao Gong,Shuai Zeng,Xiaowei Li,Bin Hu,Jianxiu Li,Shuting Sun,Lan Zhang
At present, depression has become a main health burden in the world. However, there are many problems with the diagnosis of depression, such as low patient cooperation, subjective bias and low accuracy. Therefore, reliable and objective evaluation method is needed to achieve effective depression detection. Electroencephalogram (EEG) and eye movements (EMs) data have been widely used for depression
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A Parallel Cerebrovascular Segmentation Algorithm Based on Focused Multi-Gaussians Model and Heterogeneous Markov Random Field. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-22 Zhilong Lv,Fubo Mi,Zhongke Wu,Yicheng Zhu,Xinyu Liu,Mei Tian,Fa Zhang,Xingce Wang,Xiaohua Wan
A complete and detailed cerebrovascular image segmented from time-of-flight magnetic resonance angiography (TOF-MRA) data is essential for the diagnosis and therapy of the cerebrovascular diseases. In recent years, three-dimensional cerebrovascular segmentation algorithms based on statistical models have been widely used, but the existed methods always perform poorly on stenotic vessels and are not
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Link Prediction Only With Interaction Data and its Application on Drug Repositioning. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-24 Juan Liu,Zhiqun Zuo,Guangsheng Wu
To assist drug development, many computational methods have been proposed to identify potential drug-disease treatment associations before wet experiments. Based on the assumption that similar drugs may treat similar diseases, most methods calculate the similarities of drugs and diseases by using various chemical or biological features. However, since these features may be unknown or hard to collect
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Breast Cancer Candidate Gene Detection Through Integration of Subcellular Localization Data With Protein-Protein Interaction Networks. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-24 Xiwei Tang,Qiu Xiao,Kai Yu
Due to technological advances the quality and availability of biological data has increased dramatically in the last decade. Analysing protein-protein interaction networks (PPINs) in an integrated way, together with subcellular compartment data, provides such biological context, helps to fill in the gaps between a single type of biological data and genes causing diseases and can identify novel genes
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Anomaly Detection-Based Recognition of Near-Native Protein Structures. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-27 Sivani Tadepalli,Nasrin Akhter,Daniel Barbara,Amarda Shehu
The three-dimensional structures populated by a protein molecule determine to a great extent its biological activities. The rich information encoded by protein structure on protein function continues to motivate the development of computational approaches for determining functionally-relevant structures. The majority of structures generated in silico are not relevant. Discriminating relevant/native
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Similar Disease Prediction With Heterogeneous Disease Information Networks. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-05-25 Jianliang Gao,Ling Tian,Jianxin Wang,Yibo Chen,Bo Song,Xiaohua Hu
Studying the similarity of diseases can help us to explore the pathological characteristics of complex diseases, and help provide reliable reference information for inferring the relationship between new diseases and known diseases, so as to develop effective treatment plans. To obtain the similarity of the disease, most previous methods either use a single similarity metric such as semantic score
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An Efficient Double-Layer Blockchain Method for Vaccine Production Supervision. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-03 Shaoliang Peng,Xing Hu,Jinglin Zhang,Xiaolan Xie,Chengnian Long,Zhihui Tian,Hongbo Jiang
A vaccine is a biological product which is an important means for human beings to protect themselves. Most of its users are young children with weak immunity. Once a vaccine has a problem, it will pose a serious threat to the lives of many people. At present, the supervision of vaccine production is very simple. The vaccine production record is completely controlled by the enterprises. Enterprises
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IEEE Transactions on NanoBioscience information for authors IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-30
These instructions give guidelines for preparing papers for this publication. Presents information for authors publishing in this journal.
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Ultrashort Peptide Theranostic Nanoparticles by Microfluidic-Assisted Rapid Solvent Exchange. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-07-03 Ming Ni,Guillaume Tresset,Ciprian Iliescu,Charlotte A E Hauser
Ultrashort peptides (USPs), composed of three to seven amino acids, can self-assemble into nanofibers in pure water. Here, using hydrodynamic focusing and a solvent exchange method on a microfluidic setup, we convert these nanofibers into globular nanoparticles with excellent dimensional control and polydispersity. Thanks to USP nanocarriers’ structure, different drugs can be loaded. We used Curcumin
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From local to global: a graph framework for retinal artery/vein classification. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-23 Fan Huang,Tao Tan,Behdad Dashtbozorg,Yi Zhou,Bart M Ter Haar Romeny
Fundus photography has been widely used for inspecting eye disorders by ophthalmologists or computer algorithms. Biomarkers related to retinal vessels plays an essential role to detect early diabetes. To quantify vascular biomarkers or the corresponding changes, an accurate artery and vein classification is necessary. In this work, we propose a new framework to boost local vessel classification with
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A glucose monitoring system with remote data access. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-06-15 Ankit Baingane,Gymama Slaughter
A cost-effective portable glucose monitoring system with remote data access based on a novel e-oscilloscope was developed using a glucose biofuel cell and a capacitor circuit interfaced to an ESP8266 microcontroller programmed to convert the charge/discharge rates of the capacitor functioning as a transducer. The capacitor charge/discharge rates were converted into glucose concentration readings that
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Three-Variable Chaotic Oscillatory System Based on DNA Strand Displacement and Its Coupling Combination Synchronization. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-22 Yanfeng Wang,Zhi Li,Junwei Sun
The synchronization control of two chaotic oscillatory systems is designed based on DNA strand displacement in the present work. Thus, combination synchronization of three 3-variable chaotic oscillatory systems is proposed based on DNA strand displacement. Firstly, five chemical reaction modules of double, displacement, adjustment, catalysis and degradation are designed. Based on these five modules
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Editorial A(nother) New Beginning in 2020! IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-04-13 Dan V. Nicolau
Severe circumstances, such as the present pandemic, require us to focus on immediate and major concerns, but they also ask us to reflect on where we were, are, and want to be in the future. In doing so, severe circumstances are, essentially, asking us to design a future, one with new emphases, attitudes and activities, and which will mitigate, solve, or outright remove the present critical problems
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Sol-Gel-Based Electrospray Synthesis of Barium Titanate Nanoparticles. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-01-03 Amanda M Uhl,Jennifer S Andrew
Barium titanate nanoparticles are desirable for a wide range of applications, spanning electronics to biomedicine. Here, we present an electrospray-based method for the synthesis of barium titanate nanomaterials, where their morphology can be altered, forming either particles or rods. As-electrosprayed particles are amorphous and spherical, but upon calcination in the presence of sodium chloride their
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Adjusting Linking Strands to Form Size-Controllable DNA Origami Rings. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-01-06 Congzhou Chen,Jin Xu,Xiaolong Shi
DNA origami is a powerful tool in nanotechnology that can be used to construct arbitrary structures for several nanoengineering applications. Generally, the more complex and sophisticated the construction, the greater is the number of origamis and connection strands that will be needed. Therefore, developing an effective and low-cost method for multiform DNA architecture is important in nanoengineering
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Development of Uric Acid Biosensor Using Gold Nanoparticles and Graphene Oxide Functionalized Micro-Ball Fiber Sensor Probe. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2019-12-10 Santosh Kumar,Ragini Singh,Guo Zhu,Qingshan Yang,Xia Zhang,Shuang Cheng,Bingyuan Zhang,Brajesh Kumar Kaushik,Feng-Zhen Liu
A highly sensitive and selective optical fiber-based enzymatic biosensor has been proposed in the present study for detection of uric acid (UA) in human serum. The working mechanism of sensor depends on surface plasma property and localized surface plasmon resonance technique. For this purpose, a micro-ball fiber sensor probe of $350~\mu \text{m}$ diameter was fabricated using advanced fusion-splicer
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Synthesis of La-Sr-Mn-O and La-Sr-Ca-Mn-O Perovskites Through Solution Combustion Using Urea at Fuel Deficient Conditions. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-01-03 I A Flores Urquizo,H Sanchez Correa,F T Montes de Oca Ayala,J Rivera de la Rosa,T C Hernandez Garcia
La 0.7 Sr 0.3 MnO 3 (LSMO) nanoparticles have been obtained via solution combustion synthesis (SCS) using urea and glycine as fuels. Also, La 0.7 Sr 0.27 Ca 0.03 MnO 3 (LSCMO) nanoparticles have been synthesized through solution combustion using urea as fuel. In this paper, the combustion process was carried out with a fuel to oxidant ratio giving fuel deficient conditions ( $\phi < {1}$ ). The thermal
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Precise Drug Delivery by Using PLGA-Based Microspheres and Optical Manipulators. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2019-12-10 Hongbo Liu,Xiaojian Li,Tanyong Wei,Shisan Xu,Shuxun Chen,Shuk Han Cheng,Dong Sun
The accurate delivery of precise amounts of drugs to a specific location can considerably affect various clinical applications. The precise control of drug amount and position is crucial to a successful drug delivery. This paper proposes the use of poly(lactide-co-glycolicacid) (PLGA)-based microspheres to contain precise amounts of drugs and an optical tweezer manipulator to transport these drug-containing
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The Effects of Subcellular Nanograting Geometry on the Formation and Growth of Bacterial Biofilms. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2019-12-04 Chang Quan Lai
Biofilm formation by bacteria protects them against environmental stresses such as desiccation, shear forces and antimicrobial agents, making them much harder to remove and increasing their virulence and persistence in industrial water systems and biomedical equipment. One promising method of disrupting biofilm formation and growth is to employ passive surface structures to inhibit bacterial adhesion
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Communication in Plants: Comparison of Multiple Action Potential and Mechanosensitive Signals With Experiments. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2019-11-04 Hamdan Awan,Kareem Zeid,Raviraj S Adve,Nigel Wallbridge,Carrol Plummer,Andrew W Eckford
Both action potentials and mechanosensitive signalling are an important communication mechanisms in plants. Considering an information-theoretic framework, this paper explores the effective range of multiple action potentials for a long chain of cells (i.e., up to 100) in different configurations, and introduces the study of multiple mechanosensitive activation signals (generated due to a mechanical
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Utilizing Neurons for Digital Logic Circuits: A Molecular Communications Analysis. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-02-24 Geoflly L Adonias,Anastasia Yastrebova,Michael Taynnan Barros,Yevgeni Koucheryavy,Frances Cleary,Sasitharan Balasubramaniam
With the advancement of synthetic biology, several new tools have been conceptualized over the years as alternative treatments for current medical procedures. This work we investigate how synthetically engineered neurons can operate as digital logic gates that can be used towards bio-computing inside the brain and its impact on epileptic seizure-like behaviour. We quantify the accuracy of logic gates
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Low-Complexity Adaptive Signal Detection for Mobile Molecular Communication. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2020-01-09 Xiaodong Mu,Hao Yan,Bin Li,Manhua Liu,Ruifeng Zheng,Yan Li,Lin Lin
Currently, most of the researches in molecular communication (MC) domain focus on the static MC scenarios. However, some envisioned important MC applications require mobile MC system. The investigation on mobile MC, especially the signal detection of mobile MC is limited. This work considers the problem of signal detection for mobile MC scenarios where the receiver nano-machine performs random movement
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Overcoming Channel Uncertainties in Touchable Molecular Communication for Direct-Drug-Targeting-Assisted Immuno-Chemotherapy. IEEE Trans. NanoBiosci. (IF 2.791) Pub Date : 2019-12-16 Neda Sharifi,Yu Zhou,Geoffrey Holmes,Yifan Chen
Objective: The performance of targeted immuno-chemotherapy of tumor is highly exposed to drug absorption in systemic circulation, which reduces its efficiency and increases side-effects. Direct drug targeting (DDT) combined with immuno-chemotherapy has the potential to mitigate the undesired systemic exposure, by using drug-loaded nanorobots to target cancer cells with the shortest possible physiological
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