Scorpion sting envenoming in Saudi Arabia posed major public health problems. Conventional treatment with antivenom with its limitations and hazards called for the use of support remediation like prazosin therapy and phytotherapy as alternative solutions in systematic medicine and a trend of use in medicinal plants. The present study is aiming to procure the medicinal plants that exhibit antidotes

Ethiopia is among the top floral biodiversity rich countries in the world. More than 7000 species of plants, 15% of they are endemic, are reported in the country. Accessibility, cultural enrichment, and cheapness make 80% of the Ethiopian people used indigenous plants for various health ailments and diseases in their traditional medical practices. Therefore, the current review examined the use patterns

Aluminium nitrate and other aluminium-containing compounds have been demonstrated to cause several health challenges. Psidium guajava L) is a well known cultivated tree with hepatoprotective nature and radical scavenging ability. Twenty-five (25) female Wistar rats with average weight of 195 g were grouped into five groups (n = 5), with their weights measured and recorded weekly throughout the period

Spinach (Spinacia oleracea) is a rich source of flavonoids and therefore widely used therapeutically as an antioxidant agent in traditional medicine. The present study was undertaken to study the bone regenerating property of dried Spinacia oleracea extract (DSE) and self-emulsifying formulation of the extract (FDSE) on drill-hole model of fracture repair in rats. 0.8 mm hole was drilled in the diaphyseal region

Chewing sticks are commonly used as oral hygiene tool in Africa and reactive oxygen species have been linked to the cause of degenerative diseases because of their ability to induce oxidative damage to biological molecules. Plants have been a long source of dietary antioxidants as most plants have been found to exhibit excellent antioxidant potentials. Mezoneuron benthamianum is a plant that is used

The present study was designed to explore the food-drug and pharmacokinetic interaction between C.frutescens, a culinary herb on hypoglycemic activity of glimepiride, a sulfonyl urea derivative used in the treatment of type-2 diabetes) in diabetic rats in combination of each as single doses for one day. Further it is also aimed to study the effect of AQEFCF on antidiabetic effect of glimepiride by

Gardenia gummifera L.f. (Family: Rubeacea) is used in indigenous system of medicine to cure many diseases. To authenticate the traditional medicinal claim investigation has been under taken to evaluate the antioxidant and hepatoprotective activities of Gardenia gummifera L.f. fruit methanol extract (GFME). GFME was evaluated using various antioxidant assays, including DPPH and Nitric oxide radical

Citrus sinensis is one of the most abundant citrus species consumed. Orange peels are a waste by-product of the fruit and may potentially contain useful phytonutrients with biological relevance. Fresh and dry peels of sweet orange were subjected to Soxhlet extraction and then concentrated using a rotary evaporator. Total phenolic, flavonoid and tannin content were determined using standard methods

Therapeutic potential of Prosopis cineraria has been extensively explored by many eminent researchers against various serious diseases but its activity against Lipopolysaccharide (endotoxin) is obscure. Therefore, present experimental investigation was conducted to unravel and analyze the anti-inflammatory potential of hydro-ethanol extract of Prosopis cineraria against LPS-induced inflammation in

Quercus infectoria (Fagaceae family) is traditionally used for treatment of vaginal discharge, prolapse, laxity, and many other female genital disorders. Two important parts of plant including oak fruit hulls (Jaft-E-Baloot) and oak galls (Mazo) are recommended to use for female genital disorders, although, they have many other medicinal applications on skin, urinary and respiratory tract. Tannins

An amendment to this paper has been published and can be accessed via the original article.

In the present investigation an attempt was made to evaluate the potential of agnucastoside C (ACC), isolated from the leaves of Moringa oleifera in ameliorating thyrotoxicosis, hepatic lipid peroxidation (LPO) and hyperglycemia in female mice. L-thyroxine (L-T4) at 0.5 mg/kg/d was administered through intra-peritoneal route for 15 consecutive days to induce thyrotoxicosis and then the effects of three

Spathodea campanulata P. Beauv. (Bignoniaceae) is a very common plant in Bangladesh which is locally called “Rudrapalash”. In Nigeria leaves extract of S. campanulata has a reputation of being used as an anticonvulsant. In this connection, the aim of this study was to investigate other neuropharmacological effects like sedative and anxiolytic activities of methanol extract of S. campanulata (MESC)

Herbal medicines are used for the treatment of many infectious diseases throughout the history of mankind. The increasing antibiotic resistance exhibited by microorganisms has led to the phytochemical screening of medicinal plants for antimicrobial activity. Many infections can be treated by phytochemicals possessing potent antibacterial efficiency. The pharmacological activities of any plant is because

An amendment to this paper has been published and can be accessed via the original article.

Overdose of paracetamol affects liver cells leading to cell death. This is done through hepatic necrosis, which is characterized by a rupture of the plasma membrane. A variety of investigations has been conducted using herbal extracts to assess liver toxicity induced by paracetamol. Here we examined herbal plant species, Acridocarpus orientalis (A. orientalis), ethanolic extract to study its potential

An amendment to this paper has been published and can be accessed via the original article.

The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part. Trypanosoma brucei brucei was identified by PCR, cultured in Dulbecco’s Modified Eagle Medium (DMEM) and incubated at 37 °C and 5% CO2. Subsequently, the cultured T. brucei brucei were

In an attempt to explore the scientific basis for the pharmacological benefits the antioxidant and antimicrobial activities of Ipomoea mauritiana whole plant methanol extract were assessed. The total phenolic and flavonoid content were determined using standard method while antioxidant activity was determined by DPPH free radical scavenging activity method. The antimicrobial activity was evaluated

α-Amylase catalyses the hydrolysis of starch and ultimately producing glucose. Controlling the catalytic activity of this enzyme reduces glucose production in the postprandial stage, which could be a therapeutic benefit for people with diabetes. This study was conducted to evaluate α-amylase inhibition for utilizing the crude extracts of some medicinal plants traditionally used in Nepal for the treatment

Various parts i.e., stem bark, leaf, root and flower of Neolamarckia cadamba (Roxb.) Bosser has been extensively used by traditional practitioners to treat all types of diabetes. Our present study investigated the antidiabetic property of the extract from its flower and evaluated its traditional use for diabetes. Phenolic contents were found to be higher in the methanol soluble fraction (MESF) (228

Antigonon leptopus is a medicinal plant its leaves has not been reported for protective effects against cadmium induced hepatorenal toxicity. Cadmium (Cd) is a non-essential toxic metal used in industrial process, causes severe risk to human health with high levels. It is accumulated primarily in liver and kidney. Male Wistar albino rats (200-250 g) were divided into 6 groups (n = 6) and had free access

The stem bark aqueous alcohol extract of Poincianella pluviosa (PPSB extract) is rich in bioactives including gallic acid, gallic acid methyl ester, pyrogallol, ellagic acid, corilagin, 1,4,6-tri-O-galloyl-glucose, 1,2,3,6-tetra-O-galloyl-glucose, 1,2,3,4,6-penta-O-galloyl-glucose, tellimagrandin I, tellimagrandin II, mallotinic acid, mallotusinic acid, and geraniin. The aim of the present study was

This study was aimed at evaluating the hematinic effect of Spondias mombin and its protective role against the spleenotoxic effect of Phenylhydrazine (PHZ). Thirty Wistar rats were randomized into 6 groups. Group A (Control) animals were neither given the extract nor PHZ. Rats in groups B and C were administered 150 mg/kg body weight and 300 mg/kg body weight doses of the extract respectively. Anemia

Enantia chlorantha is a local medicinal plant commonly use in Nigeria for the treatment of diabetes but without support of scientific data. Large percentage of people suffering from diabetes who uses the plant as antidiabetic agent also combine its administration with standard antihypertensive drugs. In the present study, we have investigated the possible toxicological effects of combined administration

There is high incidence of liver and kidney diseases worldwide but medicinal plants may provide remedy. This study evaluated and compared the protective effects of Cassia spectabilis extract (CSE) and Newbouldia laevis extract (NLE) against diclofenac (DF) induced hepatorenal oxidative damage in rats. Twenty four rats were divided into 4 groups with 6 rats in each. Normal saline was given to the rats

The present study evaluated the phytochemical profiles, anti-oxidants, antimicrobial, anti-inflammatory, analgesic, anti-arthritic and wound healing effect of methanol and ethyl-acetate extracts of Azanza garckeana. Methanol extract had higher phenol, flavonoids and alkaloids concentrations, ferric reducing antioxidant power (FRAP) and hydroxyl radical scavenging activities than ethyl-acetate extract

Cuscuta reflexa (C. reflexa) Roxb. (Convolvulaceae) has medicinal properties for the effective management of several aliments including diabetes mellitus, inflammation, and gastric ulcer. The present investigation focuses on the antidiabetic potential of C. reflexa leaves methanol extract in alloxan-induced diabetic rats. The antidiabetic activity of C. reflexa leaves methanol extract (CRME) was evaluated

Insulin secretion and insulin related pathways have been the prime targets in the treatment of diabetes for a long time. However, recently a lot of attention is being directed towards addressing hyperglycaemia as the main perpetrator of the symptoms in this metabolic disorder. This new treatment approach also involves greater inclination to plant derived therapeutic agents for their safety and probable

The current study undertaken to evaluate antioxidant property of Solanum macranthum fruit methanol extract and its in-vitro cytotoxic effects on breast cancer MDA-MB-231 and mice embryo fibroblast (MEF-L929) cell line. The total alkaloids, phenols and flavonoids content in the methanol extract of S.macranthum fruit were estimated. The antioxidant activity was evaluated by FRAP assay, H2O2 scavenging

Sphaeranthus indicus is an important medicinal plant, which is used to cure various illnesses. The present study is the first investigation of the antimicrobial, antioxidant and phytochemical analysis of Sphaeranthus indicus from Chhattisgarh, India. The whole plant and plant parts were extracted with polar and non-polar solvents such as water, methanol, ethyl acetate and hexane to assess various bioactivities

Stem bark of Anogeissus latifolia Roxb (family: Combretaceae) is used traditionally and ethnomedicinally to alleviate pain, inflammation and fever conditions. The current study investigates the analgesic, anti-inflammatory and antipyretic activities of ethanolic extract of stem bark of Anogeissus latifolia Roxb. The HPLC studies were carried out to standardize the stem bark ethanolic extract of Anogeissus

Lepidium pinnatifidum is a multipurpose, beneficial plant and known well for its indigenous therapeutic standards. Current study is aimed to investigate antioxidant and anti-inflammatory potency of Lepidium pinnatifidum. L. pinnatifidum dried powder was extracted with crude methanol (LPM) and then fractionated with various solvents to get respective fractions, termed as, n-hexane (LPH), chloroform

Diabetic is one of the fundamental persuasive of diabetic nephropathy and significantly sparks off kidney diseases and end stage renal failure globally. The current research was carried out to evaluate hypoglycemic potential and nephroprotective effect of ethanolic extract of Mikania scandens leaves by using alloxan-induced diabetic nephropathy (DN) mice. The mice were intraperitoneally treated with

Lemongrass (Cymbopogon citratus Stapf) tea is a widely consumed beverage for nourishment and the remedy of diabetes mellitus (DM) in Africa locally. The aim of the present study was to investigate the antidiabetic action of lemongrass tea (LGT) in a type 2 diabetes (T2D) model of rats. The fructose-streptozotocin (STZ) animal model for T2D was used and the LGT was prepared by boiling for 10 min in

Diabetes is a chronic metabolic disorder which affects millions of people every year. If diabetes is not controlled, it can cause serious damage and a number of health complications. The aim of this paper was to review published ethnobotanical and ethnopharmacological evidences of Moroccan plants with antidiabetic potentials. Publications describing the medicinal plants used for the treatment of diabetes

In the original publication of this article [1], an author name was misspelt. Instead of Kishore Mozumder, the author name should be Kishor Mazumder.

Consumption of plant-derived nutraceuticals and crude drugs in Arab traditional medicine is widely believed to confer beneficial effects in liver and kidney diseases. Fruits from the date palm Phoenix dactylifera L. are a rich source of nutrients and bioactive phytochemicals which possess a myriad of pharmacological effects. Herein, we examined the impact of Date Palm Pollen (DPP) aqueous suspension

Infertility is a global health burden which affect more than 15% of couples’ population. An impaired hormonal balance, oxidative stress and alteration in the physiological function of the reproductive organ are factors leading to infertility. The present study investigated the protective role of methanolic leaf extract of Vernonia amygdalina (MLVA) against Nitrobenzene-induced oxidative testicular

Avocado (Persea americana) is one of the plants widely used in ethnomedicine in Nigeria. The present study was aimed at investigating effects of aqueous Avocado (Persea americana) leaf extract on total cholesterol, triacylglycerols, protein and haematological parameters in carbon tetrachloride (CCl4)-intoxicated rats. We evaluated the possible effects of pre-treatment with aqueous extract of Persea

Jatropha tanjorensis is a commonly consumed green leafy plant that has found usage in folk medicine. Sodium benzoate (C6H5COONa) is a widely used preservative in food/drink industries with potential cytotoxicity. Protective effect of some leafy plants on xenobiotic-induced toxicity have been established. Hence, this study sought to investigate the protective effect of methanolic leaf extract of Jatropha

In the present era, the attention of nutritionist diverted towards the bioactive entities present in natural sources owing to the presence of health boosting perspectives against lifestyle related disarrays. In this context, different parts of ginger crop i.e. rhizome, leaves and flower of variety Suravi (ID no. 008) were used for the preparation of ginger extracts with 50% methanol, 50% ethanol and

This brief communication summarizes the key highlights presented at the 2019 Phytoneering Research and Experience Summit held at the Palma Convention Centre and the educational finca Sa Canova (Majorca, Spain) from the 25th to the 27th of July 2019. More than 100 professionals from academia, industry and public services took part. The scientific programme included three dedicated symposium sessions

Hydroxamic acids are currently being used in diverse biological activities. We investigated the effect of hydroxamic acid, synthesized from Cyperus esculentus seeds, on the antioxidant status of the liver, spleen, and kidney of Wistar rats. Twenty male rats were randomly divided into three treatment groups using hydroxamic acid at doses of 5, 15, and 50 mg/kg and a control group using distilled water

The Mediterranean region is characterized by a diverse vegetation cover, and the Lavandula genus is one of the most important medicinal and aromatic plants in this region. It has been used in traditional medicine as a treatment for anxiety and insomnia and to improve sleep quality for a long history. Lavender is commonly used in perfumes, soaps, bath powders, and scented sachets. It can flavor teas

In this present study, antioxidant, anti-hemolytic, cytotoxic and anti-bacterial activities derived from methanol extracts of Bruguiera gymnorrhiza and Heritiera littoralis were investigated in order to determine their medicinal activities. Folin-Ciocalteu reagent method and aluminum chloride methods were used to determine the mangroves’ total phenolics and total flavonoid content, respectively. Antioxidant

A significant role in the pathogenesis of rhinosinusitis is played by an inflammatory reaction in the maxillary sinuses of the nasal cavity. Leukotrienes are the most powerful mediators of inflammation, especially at the early stages. The effect of combined dry extract BNO 1016 could be useful for the inhibition of the inflammation in rhinosinusitis. Thus, it appears reasonable to study the anti-inflammatory

This review summarizes selected scientific evidence on phytochemistry and pharmacological properties of Ammodaucus leucotrichus. Information was gathered via the Internet (using Scopus, PubMed, Google Scholar, Elsevier, Springer, Science Direct, Researchgate and Web of Science) as well as from libraries and local books. Ammodaucus leucotrichus (A. leucotrichus), belongs to the family Apiaceae, has

Flaxseed has emerged as a potential source of bioactive components that can be utilized in routine diet to address lifestyle disorders. In this context, three studies were carried out on the basis of induction therapies i.e. Study I (Normal diet), Study II (Hyperglycemic diet; 40% sucrose) and Study III (Hypercholesterolemic diet; 1.5% cholesterol) using Sprague Dawley rats. Each study was further

Hepatorenal injuries and dyslipidemia are common global health challenges but medicinal plant extracts may have potential to prevent them. Thus, this study evaluated the protective effect of aqueous extract of Lophira lanceolata leaf (LLE) against cisplatin-induced hepatorenal injuries and dyslipidemia in albino Wistar rats. Thirty rats were randomly divided into 6 groups of 5 rats each. Group I rats

The current objective is to evaluate the effect of frankincense oil on the convulsions and the associated neurochemical alterations produced in pilocarpine-induced status epilepticus rat model. Rats were divided randomly into: control, status epilepticus rat model and rat model of status epilepticus pretreated with frankincense oil daily for 5 days before pilocarpine treatment. On the fifth day, after

In the original publication of this article [1], two authors' names are not complete.

The unopened buds of the fruit of Harungana madagascariensis is used in the treatment of anaemia and skin diseases in traditional medicine. Hence, this study aims to scientifically evaluate the effects of oral administration of the fruit extract of Harungana madagascariensis on haematological, biochemical and histological parameters in Wistar rats. Phytochemical screening of the ethanol fruit extract

Justicia secunda Vahl. is a medicinal plant used in ethnomedical practice as therapy to manage inflammation. Therefore, this study was designed to evaluate the anti-inflammatory activity of methanol extract of J. secunda leaves (MEJSL) using in vitro and in vivo inflammation models. Seventy-percent MEJSL was prepared following standard procedure. In vitro anti-inflammatory assays were performed using

Obesity is a health problem in many countries, and maintaining a perfect weight is challenging. Moringa oleifera leaf extract (ME) is rich in polyphenols with antioxidant and pharmaceutical potential. The present study investigated the potential protective effect of Moringa oleifera leaf extract against obesity induced from a high-fat diet (HFD), oxidative stress and disruption of metabolic hormones

The goal of this study was to explore the inherent antioxidant and antineoplastic activities of methanolic extract of the roots of Hibiscus sabdariffa (MEHSR). The dried coarse powder of roots of Hibiscus sabdariffa was subjected to methanolic extraction. Here in vitro methods were used to determine the various types of phytochemical content and antioxidant activity of MEHSR as well as its cytotoxic

Ethnobotany knowledge in a community has shaped local wisdom in utilizing plants to treat diseases, such as the use of Malaka (Phyllanthus emblica) flesh to treat type 2 diabetes. This study presented evidence that the phenolic extract of the Malaka flesh could reduce blood sugar levels in the diabetic induced rats. The phenolic extract of the P. emblica was administrated to the glucose-induced rats

Abrus precatorius possesses various therapeutic properties including anticancer potentials. This study evaluated the anti-proliferative activities of fractions of methanol root extract of A. precatorius on breast and cervical cancer cells and their immunomodulatory effect. Phytochemical screening was done by FTIR and GCMS. In vitro anti-proliferative effect was evaluated on human breast cancer (AU565)

Vitellaria paradoxa (V. paradoxa) is a plant used in traditional medicine in the treatment of many diseases including diabetes mellitus. Although the different parts of this plant are used empirically as antidiabetic drug, no scientific work to our knowledge has yet been undertaken to evaluate its effects on blood glucose, and lipid and antioxidant parameters of diabetic animals. The objective of this

Caesalpinia bonducella L. is well known and extremely valuable herb in ayurvedic system of medicine. The present study is aimed to design the evaluation of aqueous extract of Caesalpinia bonducella L. on doxorubicin induced myocardial infarction in wistar strains of albino rats of both sex. The experimental animals are divided in to 5 groups of 6 animals each. Group I (Normal Control), Group II (Negative