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Effect of social media use on learning, social interactions, and sleep duration among university students Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Manjur Kolhar; Raisa Nazir Ahmed Kazi; Abdalla Alameen
Background Social networking sites are widely used by university students. This study investigated the purposes for which social networking sites are used and their effects on learning, social interaction, and sleep duration. Material and Methods A cross-sectional study was conducted among 300, 17–29-year-old female students at Prince Sattam bin Abdul Aziz University. A questionnaire was used to collect
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In silico annotation of unreviewed acetylcholinesterase (AChE) in some lepidopteran insect pest species reveals the causes of insecticide resistance Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Qudsia Yousafi; Ayesha Sarfaraz; Muhammad Saad Khan; Shahzad Saleem; Umbreen Shahzad; Azhar Abbas Khan; Mazhar Sadiq; Allah Ditta Abid; Muhammad Sohail Shahzad; Najam ul Hassan
Lepidoptera is the second most diverse insect order outnumbered only by the Coeleptera. Acetylcholinesterase (AChE) is the major target site for insecticides. Extensive use of insecticides, to inhibit the function of this enzyme, have resulted in the development of insecticide resistance. Complete knowledge of the target proteins is very important to know the cause of resistance. Computational annotation
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Murine Double Minute 2 Gene (MDM2) rs937283A/G variant significantly increases the susceptibility to breast cancer in Saudi Women Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Weam Talal Yehya Shebli; Mohammad Kdaimes H.Alotibi; Rawya Ibrahim AL-Raddadi; Razan Jamaan Al-amri; Emad Ibrahim Yagoub Fallatah; Ahmed Safar Alhujaily; Hiba Salaheldin Mohamed
Breast cancer is predominant causes of mortality in women worldwide. Genetic polymorphisms have a significant role in breast cancer aetiology. TP53 and its inhibitor the murine double minute 2 (MDM2) genes encode proteins that have crucial functions in the DNA damage response. The allelic variations within these genes could influence the susceptibility to breast cancer. MDM2 promotor polymorphism rs937283A/G
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Efficiency of Plant Growth Promoting Bacteria for Growth and Yield Enhancement of Zea mays (Maize) Isolated from Rock Phosphate Reserve Area of Hazara, KPK, Pakistan Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Rimsha Zainab; Ghulam Mujtaba Shah; Waqar Khan; Ayaz Mehmood; Rashid Azad; Khurram Shahzad; Tariq Sultan
The usage of novel plant growth-promoting rhizobacteria (PGPR) as bioinoculant is a good opportunity for ecological farming practices to improve soil condition, quality of grain, crops’ yield and biodiversity conservation. The purpose of recent research was focused to examine, isolate and characterize PGP bacteria that colonize the rhizosphere for the duration of the maize plant's seedling. For this
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Triphala extract negates arecoline-induced senescence in oral mucosal epithelial cells in vitro Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Shankargouda Patil; Sachin C Sarode; Heba Ashi; Hosam Ali Baeshen; A. Thirumal Raj; Kamran H Awan; Shailesh Gondivkar; Amol Ramchandra Gadbail; Gargi S. Sarode
Background Arecoline found in areca nut causes oral submucous fibrosis. Triphala is an Ayurvedic medicinal preparation used to improve overall physical wellness that has also been shown to improve oral health. Objectives To assess the activity of Triphala extract on arecoline-induced senescence in oral mucosal epithelial cells in vitro. Materials and methods Oral mucosal epithelial cells were isolated
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Hydrocarbon Biodegradation and Transcriptome Responses of Cellulase, Peroxidase, and Laccase Encoding Genes Inhabiting Rhizospheric Fungal Isolates Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Mayasar I. Al-Zaban; Mohamed A. Mahmoud; Maha A. AlHarbi
By using the indigenous micro-organisms of the polluted environment to be treated, bioremediation can be a successful strategy. PCR and RT-PCR molecular techniques were applied to examine the evolution of fungal isolates through putative genes f ligninolytic enzymes like lignin peroxidase (LiP), laccase (LaC), manganese peroxidase (MnP), and cellulase (Cx) as a response to polluting of the environment
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In-silico network-based analysis of drugs used against COVID-19: Human Well-Being Study Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-21 Zarlish Attique; Ashaq Ali; Muhammad Hamza; Khalid A. al-Ghanim; Azhar Mehmood; Sajid Khan; Zubair Ahmed; Norah Al-Mulhm; Muhammad Rizwan; Anum Munir; Emin Al-Suliman; Muhammad Farooq; Zahid Ali Kaimkhani; Shahid Mahboob
Introduction Researchers worldwide with great endeavor searching and repurpose drugs might be potentially useful in fighting newly emerged coronavirus. These drugs show inhibition but also show side effects and complications too. On December 27, 2020, 80,926,235 cases have been reported worldwide. Specifically, in Pakistan, 471,335 has been reported with inconsiderable deaths. Problem Statement: Identification
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Interference of horse purslane (Trianthema portulacastrum L.) and other weeds affect yield of autumn planted maize (Zea mays L.) Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Khuram Mubeen; Muhammad Waqas Yonas; Ahlam Khalofah; Rao Muhammad Ikram; Naeem Sarwar; Muhammad Shehzad; Allah Wasaya; Haseeb ur Rehman; Tauqeer Ahmad Yasir; Mudassir Aziz; Mahmood Alam; Hafiz Muhammad Rashad Javeed; Mazhar Ali Khan; Muqarrab Ali; Matlob Ahmad; Abdul Khaliq; Muhammad Abdul Qayyum; Wazir Ahmad; Khalid Ali Khan
To assess comparative losses of Trianthema portulacastrum (HP) relative to other weeds, the experiment was set during consecutive summer seasons 2018 and 2019 at the Research Farm MNS-University of Agriculture, Multan, Pakistan. Experiment consisted three replications which were laid out under randomized complete block design. Experiment consisted of ten treatments viz: weeds free (whole season), HP
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Harnessing the Potential of Plant Transcription Factors in Developing Climate Resilient Crops to improve global food security: Current and Future Perspectives Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Rahil Shahzad; Shakra Jamil; Shakeel Ahmad; Amina Nisar; Zarmaha Amina; Shazmina Saleem; Muhammad Zaffar Iqbal; Rana Muhammad Atif; Xiukang Wang
Crop plants should be resilient to climatic factors in order to feed ever-increasing populations. Plants have developed stress-responsive mechanisms by changing their metabolic pathways and switching the stress-responsive genes. The discovery of plant transcriptional factors (TFs), as key regulators of different biotic and abiotic stresses, has opened up new horizons for plant scientists. TFs perceive
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Determination of phylogenetic relationships among methicillin-resistant Staphylococcus aureus recovered from infected humans and Companion Animals Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Hassan A. Hemeg
Companion animals carry different microorganism of severely public health hazard for human; the kindness relation and contact between humans and companion animals may the route in the transmission of most zoonotic bacteria, including Methicillin-Resistant Staphylococcus aureus (MRSA). Therefore, the current study investigate the companion animals mainly dogs and cat as a reservoir for MRSA and the
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A Study on Risk assessment of Effect of Hematoxylin dye on cytotoxicity and nephrotoxicity in Freshwater Fish: Food and water security prospective research Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Bilal Hussain; Hira Yaseen; Khalid-Al-Ghanim; F. Al-Misned; Muhammad Qasim; N. Al-Mulhm; Shahid Mahboob
The cytotoxicity in freshwater fishes due to different industrial dyes in industrial effluents is a major worldwide issue. Hematoxylin dye has a wide range of uses in textile industries and laboratories. This study was aimed to evaluate the toxic effects of hematoxylin's sublethal effect in vitro in Cirrhinus mrigala. The fish was exposed to different grading concentrations of dye in the aquarium.
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Characterization of the native honey bee (Apis mellifera jemenitica) in the south western region of Saudi Arabia using morphometric and genetic (mtDNA COI) characteristics Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Enas A. A. Alabdali; Hamed A. Ghramh; Essam H. Ibrahim; Zubair Ahmad; Asma N. Asiri
Apis mellifera jemenitica incorporates a few perceived subspecies that vary in their natural properties and farming qualities. Mitochondrial COI gene sequence (mtCOI) has not been used before for bee identification in the southwestern region of Saudi Arabia. The aim of this work was to study the morphometry and analyzing the mtCOI of all collected bees. The nucleotide sequence of the mtCOI gene was
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Spatio-Temporal Analysis of Egyptian flower mantis Blepharopsis mendica (Order: Mantodea), with notes of its future status under climate change Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Mohamed Nasser; Mohammed Okely; Omaima Nasif; Sulaiman Alharbi; Sohair GadAllah; Sami Al-Obaid; Rabia Enan; Madhu Bala; Sara Al-Ashaal
Egyptian flower mantis Blepharopsis mendica (Order: Mantodea) is a widespread mantis species throughout the southwest Palaeartic region. The ecological and geographical distribution of such interesting species is rarely known. So, through this work, habitat suitability models for its distribution through Egyptian territory were created using Maxent software from 90 occurrence records. One topographic
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Assessing the potential use of chitosan scaffolds for the sustained localized delivery of vitamin D Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Archana A Gupta; Supriya Kheur; Ravindra V. Badhe; A. Thirumal Raj; Ramesh Bhonde; Amit Jaisinghani; Nishant Vyas; Vikrant R Patil; Yaser Ali Alhazmi; Sameena Parveen; Hosam Ali Baeshen; Shankargouda Patil
Vitamin D is a commonly used bone modulator in regenerative medicine. Several modalities have been explored for the delivery of vitamin D including nanoparticles and scaffold. The present study aimed to assess the potential use of a bio-degradable chitosan scaffold for the delivery of vitamin D. The objectives included fabrication of a bio-degradable chitosan scaffold, integration of vitamin D into
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Effects of fermentation treatments on Polygonatum odoratum flavones’ antioxidant activities Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Guang-Hui Xia; Xin-Hua Li; Zhen Zhang; Yu-hang Jiang
The main aim of this study is to analyze antioxidant properties of Polygonatum odoratum fermented with bacteria, fungi and yeast. Antioxidant activities (1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging, hydroxyl radical scavenging, and anti-lipid peroxidation abilities) were assessed in samples of flavones isolated from fermented P. odoratum (Mill.) druce samples. Fermentations using Lactobacillus
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Dysregulation of exosomal miR-192 and miR-194 expression in Lung adenocarcinoma patients Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Tongfei Wang; Wei Li; Haitao Li; Weina Li
Non-small cell lung cancer (NSCLC) is the main reason of cancer linked mortality and around 80% of cases diagnosed in advanced stage. Therefore current study designed to evaluate the deregulation of miRNA-194 and miRNA-192 in different body fluid of Non small cell lung cancer participants. Present study recruited newly diagnosed histopathologically confirmed. It was observed that the 40% NSCLC participants
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Multidrug-resistant Escherichia coli in Raw Milk: Molecular Characterization and the potential impact of camel’s Urine as an Antibacterial Agent Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-20 Ayman Elbehiry; Eman Marzouk; Ihab M. Moussa; Afrah Alenzi; Khalid S. Al-Maary; Ayman S. Mubarak; Hanan D. Alshammari; Dalia Al-Sarar; Roua A. Alsubki; Hassan A. Hemeg; Saleh A. Kabli
Raw milk is one of the most important vehicles for transmitting various pathogens, especially Escherichia coli (E. coli). Multidrug-resistant pathogens are highly prevalent among mastitic cows in various dairy farms worldwide. Therefore, our current study is based on the identification of E. coli from mastitic cow’s milk and their resistance to various antibacterial agents. As well, the impact of camel’s
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Potential Bangle (Zingiber montanum J.König) Rhizome Extract as a Supplement to Prevent and Reduce Symptoms of Covid-19 Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-16 Muhammad Yanis Musdja
The morbidity and mortality rates due to Covid-19 are increasing day by day, to overcome this, we urgently need a better treatment strategy, therefore various ways and strategies for this must be pursued. The purpose of the present review is to explain that the rhizome of bangle (Zingiber montanum) has great potential to increase antibodies and reduce symptoms of acute respiratory distress syndrome
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A comparative study of biological potentiality and EAC cell growth inhibition activity of Phyllanthus acidus (L.) fruit pulp and seed in Bangladesh Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-16 Ajmeri Sultana Shimu; Masum Miah; Mutasim Billah; Sumon Karmakar; Sumon Chandro Mohanto; Ratna Khatun; Md. Abu Reza; Kazi Md. Faisal Hoque
Medicinal plant-derived bioactive compounds have recently gained more interest in biological research as an important source of novel drug candidates. Phyllanthus acidus (L.) is a widely distributed herbal medicinal plant naturally used in Ayurvedic medicine in Bangladesh. The present study focused on exploring the biological potential as well as the inhibitory effect of EAC cell growth with a comparative
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Catalytic Degradation of Methylene Blue Using Silver Nanoparticles Synthesized by Honey Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-15 Mayasar I. Al-Zaban; Mohamed A. Mahmoud; Maha A. AlHarbi
This investigation displayed the good catalytic activity of silver nanoparticles (AgNPs) on the reduction of methylene blue dye. During this work, Honey was chosen for environmentally reducing and stabilizing agents for preparation of silver nanoparticles then characterized these nanoparticles by ultraviolet-visible spectroscopy (UV-Vis), functional biomolecules were confirmed by Fourier transform
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Molecular characterization of ticks and tick-borne piroplasms from cattle and camel in Hofuf, Eastern Saudi Arabia Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-15 Sawsan A. Omer; Duha F. Alsuwaid; Osama B. Mohammed
The aims of the present study were to characterize ticks infesting the dromedary camel and cattle in Hofuf, Eastern Saudi Arabia and to determine the piroplasms that they may harbor. DNA was extracted from ticks, collected from camels and cattle, using commercial kits and subjected to polymerase chain reaction using specific primers for the amplification of ticks and piroplasms DNA. The cytochrome
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Network pharmacology-based analysis of the role of tacrolimus in liver transplantation Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-13 Lijian Chen; Yuming Peng; Chunyi Ji; Miaoxian Yuan; Qiang Yin
Background Tacrolimus is a powerful immunosuppressant and has been widely used in organ transplantation. In order to further explore the role of tacrolimus in liver transplantation, we conducted network pharmacology analysis. Methods GSE100155 was obtained from the GEO database, and the DEGs of liver transplantation were analyzed. The 2D structure of tacrolimus was obtained from the National Library
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Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-08 Fatmah S Alqahtany; Farjah H Algahtani; Mashael M Alshebly; Thamer S Albegamy; Essam S Alghamdi; Mohammed A Alnakhli; Fatimah M Madkhaly; Abdullah A Alharbi; Nawaf A Alqahtani
Factor XII (FXII) deficiency is a rare genetic blood disorder. It can lead to a higher risk of developing deep vein thrombosis or acquired thrombotic disorders than the general population. This retrospective study evaluated patients who opted for surgery and were found to have abnormal clotting profiles and clotting factors on preoperative routine blood. Patients were included regardless of whether
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Adverse effects of Atrazine on Blood parameters, Biochemical Profile and Genotoxicity of snow trout (Schizothorax plagiostomus) Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-07 Naveed Akhtar; Muhammad Fiaz Khan; Sadia Tabassum; Eman Zahran
This study was conducted to evaluate the adverse effects of atrazine on hematology, biochemistry and genotoxicity of snow trout (Schizothorax plagiostomus). Almost all treated groups presented considerably (P < 0.05) lesser values of hematocrit, hemoglobin, WBC, RBC, MCH, MCHC, monocytes and lymphocytes while significantly higher values of HCT and platelets are observed. A Significant decrease is observed
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Genome composition and genetic characterization of SARS-CoV-2 Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-06 Ayman M. Al-Qaaneh; Thamer Alshammari; Razan Aldahhan; Hanan Aldossary; Zahra Abduljaleel Alkhalifah; J. Francis Borgio
SARS-CoV-2 is a type of Betacoronaviruses responsible for COVID-19 pandemic disease, with more than 1.745 million fatalities globally as of December-2020. Genetically, it is considered the second largest genome of all RNA viruses with a 5' cap and 3' poly-A tail. Phylogenetic analyses of coronaviruses reveal that SARS-CoV-2 is genetically closely related to the Bat-SARS Like-Corona virus (Bat-SL-Cov)
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Phytochemical screening and anti-oxidant activity of Sargassum wightii enhances the anti-bacterial activity against Pseudomonas aeruginosa Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-06 Govindan Nadar Rajivgandhi; Chelliah Chenthis Kanisha; Govindan Ramachandran; Natesan Manoharan; Ramzi A. Mothana; Nasir A. Siddiqui; Adnan J. Al-Rehaily; Riaz Ullah; Omer M. Almarfadi
In this study, the phytochemical, phenolic, flavonoid and bioactive compounds were successfully screened from crude extract of Sargassum wightii by LC-MS analysis after NIST interpretation. Bacterial growth inhibition study result was shown with 24 mm zone inhibition at 200 µg/mL concentration against P. aeruginosa. The increased phenolic content was much closed to gallic acid and the range was observed
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“MR image analysis of ex-vivo mouse model of heart ischemia” Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-06 Faiz Alqarni; Mohammed Alsaadi; Fayka Karem
Introduction Myocardial infarction is one of the major causes of death and disability. Various diagnostic modalities used to investigate cardiac ischaemia. Advances in Magnetic Resonance Imaging technology has opened up new horizons for investigating the cardiac function and quantifying any pathology that may be present. Aims The present study was designed to quantify the cardiac area at risk and infarction
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Short-term administration of C. aronia stimulates insulin signaling, suppresses fatty acids metabolism, and increases glucose uptake and utilization in the hearts of healthy rats Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-06 Abdullah S. Shatoor; Suliman Al Humayed; Hussain M. Almohiy
This study evaluated the effect of Crataegus aronia (C. aronia) aqueous extract on cardiac substrate utilization and insulin signaling in adult male healthy Wistar rats. Rats (n=18/group) were either administered normal saline (vehicle) or treated with C. aronia aqueous extract (200 mg/kg) for 7 days, daily. Fasting plasma glucose and insulin levels were not significantly changed in C. aronia-treated
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In-vitro free radical scavenging effect and cytotoxic analysis of Black Cummins and Honey formulation Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-05 Bharathi Rathi; Sandhanasamy Devanesan; Mohamd S AlSalhi; Amirtham J. Ranjith Singh
Background The antioxidant potential and antiproliferative activity of the extracts of Nigella sativa seeds (Black Cummins) and honey formulations are to be explored. Method: The Gas chromatography-mass spectrum (GC-MS) and Thin Layer Chromatography (TLC) fingerprint of black Cummins and Honey formulation revealed alkaloid, saponin, volatile oil, flavonoid, glycosides, sugar, and phenolic compound
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A New Record of Generic Vascular Plant for the Flora of Saudi Arabia: Aspilia kotschyi (Asteraceae) Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-05 A. Al-Khulaidi; F. Filimban; M. Alfaifi; A. Al-Namazi
The paper presents Aspilia kotschyi (Sch.Bip. ex Hochst.) Oliv. (Asteraceae), a newly recorded genus of vascular plants, during the fieldwork in Fayfa region in the Southwest of Saudi Arabia. Flora books and scientific research papers dealing with the flora of Saudi Arabia have not mentioned any species of Aspilia genus. The taxon was found for the first time in Saudi Arabia, which makes a new addition
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Community-based observational assessment of compliance by the public with COVID19 preventive measures in the south of Saudi Arabia Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-05 Ibrahim M. Gosadi; Khaled A. Daghriri; Ahmad A. Shugairi; Ali H. Alharbi; Abdullatif Z. Suwaydi; Mohammed A. Alharbi; Ali A. Majrashi; Ibraheim A. Sumaily
Background At the end of August 2020, a surge in the number of cases in the Jazan region has been observed. The number of reported cases by 19th of August in the Jazan region was more than 300, which exceeded the number of reported cases in larger regions such as Riyadh, and Makkah. This study aims to measure compliance by the public with COVID-19 preventive measures. Methods This study was a cross-sectional
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In vitro complex formation of Human PYRIN Domain-Only Protein 3 prevented by Self-oligomerization of ASC PYD domain Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-05 Eijaz Ahmed Bhat; Nasreena Sajjad; Javeed Ahmad Tantray; Irfan A. Rather; Yan-Yan Hor
The formation of inflammasome complexes contributes inactivation of inflammatory caspases viz caspase 1, which is generally considered essential for the innate response. Three proteins constituted this inflammasome complex, such as Nod-like receptors (NLRP or AIM2), ASC possessing caspase-recruiting domain, and caspase-1. The ASC proteins comprise two domains, the N-terminal PYD domain responsible
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Effectiveness of Phytase Pre-treatment on Growth performance, Nutrient Digestibility and Mineral Status of Common Carp (Cyprinus carpio) Juveniles fed Moringa By-product Based Diet Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-04 M.M. Shahzad; S. Bashir; S.M. Hussain; A. Javid; M. Hussain; N. Ahmed; M.K.A. Khan; M. Furqan; I. Liaqat; T. Rafique; F. Khalid
Several anti-nutritional substances are found in plant derivatives for example phytate, that make the nutrients and minerals unavailable to fish, hence leading to poor growth performance. Presence of the anti-nutrient factor such as phytate is a chelated compound and need enzyme for its breakdown and availability of nutrients to improve fish growth. This research work was performed to check the improvement
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Antiproliferative and antioxidant properties of nematocysts crude venom from Jellyfish Acromitus flagellatus against human cancer cell lines Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-02 Hemavathi Maduraiveeran; Kavitha Raja; Arulvasu Chinnasamy
This study aimed to investigate the antiproliferative and antioxidant properties of crude venom from the nematocyst of Jellyfish Acromitus flagellates on human lung cancer (A549) and liver cancer (HepG2) cell lines. The prepared crude venom was subjected to analyses of the biochemical constituents, protein profiles, antioxidant and anticancer activities by standard methods. The extracted venom was
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Phylogenetic Relationships and DNA Barcoding of Nine Endangered Medicinal Plant Species Endemic to Saint Katherine Protectorate Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-01 Ahmed M. Hashim; Aishah Alatawi; Faris M. Altaf; Sameer H. Qari; Mohamed E. Elhady; Gamal H. Osman; Heba H. Abouseadaa
A high degree of endemism has been recorded for several plant groups collectively in Saint Katherine Protectorate (SKP) in the Sinai Peninsula. Nine endangered endemic plant species in SKP were selected to test the variable abilities of three different DNA barcodes; Riboluse-1,5- Biphosphate Carboxylase/Oxygenase Large subunit (rbcL), Internal Transcribed Spacer (ITS), and the two regions of the plastid
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Insight into probiotic properties of lactic acid bacterial endosymbionts of Apis mellifera L. derived from the Polish apiary Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2021-01-01 Artur Pachla; Aneta A. Ptaszyńska; Magdalena Wicha; Magdalena Kunat; Jerzy Wydrych; Ewa Oleńska; Wanda Małek
Taking into account that fructophilic lactic acid bacteria (FLAB) can play an important role in the health of honey bees and can be used as probiotics, phenotypic properties of probiotic interest of Lactobacillus kunkeei (12 strains) and Fructobacillus fructossus bacteria (2 strains), isolated from Apis mellifera gastrointestinal tract, have been studied. We have evaluated survival of tested FLAB in
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Breeding Biology of Saunders’s tern (Sterna saundersi) in the Farasan Islands, Kingdom of Saudi Arabia Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Mohammed Almalki
Saunders’s terns (Sternula saundersi) are a small, ground-nesting marine bird species that have a massive rearing range, including the shores and islands of Asia and Africa adjacent to the north Indian Ocean. Despite occupying a large breeding range, little is known about the breeding ecology of this species. This research explored aspects of Saunders’s terns’ breeding ecology and predation rate in
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Signs of biofilm formation in the genome of Labrenzia sp. PO1 Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Madiha Zaynab; Huirong Cheng; Yufei Chen; Liao Ouyang; Xuewei Yang; Zhangli Hu; Shuangfei Li
The Labrenzia sp. PO1 strain was isolated from the A. sanguinea culture. Growth analysis revealed that strain reached a period of logarithmic growth at 24 h and the Labrenzia sp. SEM evaluated PO1 morphological characteristics. Labrenzia sp. PO1 cells can form a biofilm. In this study, the whole genome of Labrezia sp. PO1 was sequenced and annotated. The complete genome of 6.21813 Mb in size was assembled
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Nutritional Value and Bioaccumulation of heavy metals in muscle tissues of five commercially important marine fish species from the Red Sea Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Elsayed M. Younis; Abdel-Wahab A. Abdel-Warith; Nasser A. Al-Asgah; Soltan A. Elthebite; Md Mostafizur Rahman
The study evaluated the nutritional quality and investigated the heavy metals concentration in muscle tissues of five commercially important marine fish species, including brownspotted grouper (Epinephelus chlorostigma), squaretail coralgrouper (Plectropomus areolatus), black pomfret (Parastromateus niger), goldbanded jobfish (Pristipomoides multidens), and blueskin seabream (Polysteganus coeruleopunctatus)
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Artificial modification of the chemical composition of orange oil (Citrus sinensis L.) and its effect on larvicidal activity Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Jorge Anaya-Gil; Adriana Cabarcas-Caro; Miguel Leyva-Ricardo; José Parra-Garrido; Ricardo Gaitan-Ibarra; Ricardo Vivas-Reyes
The use of synthetic pesticide carries along several disadvantages talking about the preservation of the natural homeostasis of the planet, causing the searching of biopesticide, which one presents advantages as well as biodegradability in minimum possible time, the low toxicity in comparison to synthetic pesticides and their variety of structure, which allows slowing down the appearance of resistance
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Information theoretic perspective on genome clustering Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Alaguraj Veluchamy; Preeti Mehta; K.V. Srividhya; Hirendra Vikram; M.K. Govind; Ramneek Gupta; Abdul Aziz Bin Dukhyila; Raed Abdullah Alharbi; Saleh Abdullah Aloyuni; Mohamed M.Hassan; S. Krishnaswamy
Shannon’s information theoretic perspective of communication helps one to understand the storage and processing of information in these one-dimensional sequences. An information theoretic analysis of 937 available completely sequenced prokaryotic genomes and 238 eukaryotic chromosomes is presented. Information content (Id) values were used to cluster these chromosomes. Chargaff’s second parity rule
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Assessing Spirulina platensis as a dietary supplement and for toxicity to Rhynchophorus ferrugineus (Coleoptera: Dryopthoridae) Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-31 Wahidah H. Al-Qahtani
Insects are important for humanity; play role in crop pollination, and biocontrol of harmful pests. The red palm weevil, Rhynchophorus ferrugineus, is a major pest of date palms and has become a serious threat. Scientists needs ample numbers of insects for bioassays to explore control options. The alga Spirulina platensis, is enriched by protein, natural vitamins, minerals, and amino acids, stimulate
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Loranthus acaciae: Alternative medicine for β-lactamase producer and methicillin-resistant Staphylococcus aureus Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-30 Ehssan H. Moglad
Recently, we reported high antibacterial efficiency of Loranthus acaciae (LA) against different standard strains of bacteria including Methicillin-Resistant Staphylococcus aureus (MRSA). Therefore, this study aimed to confirm the effectiveness of LA against clinically isolated Staphylococcus aureus (SA) including β-lactamase producer (Blac) and MRSA. Forty-eight SA isolates collected from various clinical
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C-Phycocyanin-a novel protein from Spirulina platensis- In Vivo toxicity, Antioxidant and Immunomodulatory Studies Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-30 Priyanka Grover; Aseem Bhatnagar; Neeraj Kumari; Ananth Narayan Bhatt; Dhruv Kumar Nishad; Jubilee Purkayastha
A pigment-protein highly dominant in Spirulina is known as C-Phycocyanin. Earlier, in vitro studies has shown that C-phycocyanin is having many biological activities like antioxidant and anti-inflammatory activities, antiplatelet, hepatoprotective, and cholesterol-lowering properties. Interestingly, there are scanty in vivo experimental findings on the immunomodulatory and antioxidant effects of C-phycocyanin
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Silver nanoparticles synthesized by Nigrospora oryzae showed antifungal activity Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-29 Turki M. Dawoud; Mohamed A. Yassin; Abdel Rahim M. El-Samawaty; Abdallah M. Elgorban
In this investigation, an alternate green-route based on myco-synthesised silver nanoparticles (Ag NPs) was evaluated to control plant disease to reduce the usage of synthetic chemicals. Here, we described biologically synthesised Ag NPs using the corn grain contaminant, Nigrospora oryzae, and were well-characterised by UV-visible spectrophotometer, X-ray powder diffraction (XRD), transmission electron
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Identification of carbapenems resistant genes on biofilm forming K. pneumoniae from urinary tract infection Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-29 Govindan Nadar Rajivgandhi; Naiyf S. Alharbi; Shine Kadaikunnan; Jamal M. Khaled; Chelliah Chenthis Kanisha; Govindan Ramachandran; Natesan Manoharan; Khalid F. Alanzi
The multi-drug resistant effect of the Gram negative bacteria K. pneumoniae was identified by disc diffusion method using specific UTI panel discs of Kleb 1 HX077 and Kleb 2 HX090 HEXA. Among the multi-drug resistant bacteria, the carbapenem resistant (CR) effect of the K. pneumoniae was screened by specific carbapenem detection antibiotics of HEXA HX066 and HX0103 HEXA by disc diffusion method. In
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Phytoconstituents screening and antimicrobial activity of the invasive species Nicotiana glauca collected from Al-Baha region of Saudi Arabia Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-28 Ahmed Ali Alghamdi
Nicotiana glauca belongs to the family Solanaceae is an exotic perinnial bushy species that recently has invaded the mountainous areas of Al-Baha region, Saudi Arabia, causing degredation to soil and vegetation composition of those natural habitats. Accordingly, this plant must be removed or consumed as a source of useful products such as medicines as it has been proven to contain many effective compounds
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eGenetic Variability and Phylogenetic Analysis among Strains of Deformed Wing Virus Infesting Honey Bees and other Organisms Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-28 Hossam Abou-Shaara; Sara AlAshaal; Mohamed Nasser; Omaima Nasif; Sulaiman Alharbi
Various viruses can infect honey bees, but deformed wing virus (DWV) is considered the most dangerous virus to honey bees and has role in the sudden decline of bee colonies. This virus has different strains; however, there are no available studies to compare the characteristics of these strains utilizing bioinformatics. In this study, 27 strains of deformed wing virus were analyzed based on their sequences
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Effect of thiamazole on kainic acid-induced seizures in mice Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-12-28 Jigao Feng; Zheng Hao; Xian Zhang; Mingxia Li; Wuzhao zhong; Caicai Zhang; Ali Gharawi; Sara T. Alrashood; Haseeb A. Khan
Kainic acid (KA) induced epileptic seizures in mice is a commonly used experimental model of epilepsy. Previous studies have suggested the roles of various neurotransmitters and oxidative stress in KA-induced seizures. An important role of hypothyroidism has also been suggested in epilepsy. Thiamazole (TZ) is an anti-hyperthyroid drug with antioxidant property. This study reports the effect of TZ on
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FbD directed fabrication and investigation of luliconazole based SLN gel for the amelioration of candidal vulvovaginitis: a 2 T (thermosensitive & transvaginal) approach Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-16 Salma Firdaus; Nazia Hassan; Mohd. Aamir Mirza; Tabasum Ara; Hamed A. El-Serehy; Fahad A. Al-Misned; Zeenat Iqbal
Candidal vulvovaginitis (CVV), is the second most leading vaginal infection (global prevalence > 75%), caused due to excessive growth of Candida spp., predominantly Candida albicans (>95% cases). The current treatment regimens for CVV are marred with the challenges of fungal resistance & infection recurrence, subsequently leading to the compromised therapeutic efficacy of anti-fungal drugs, prolonged
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ZnCl2 catalyzed new coumarinyl-chalcones as cytotoxic agents Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-22 Konidala Sathish Kumar; Vijay Kotra; Phani Kumar Kola; CH.B. Praveena Devi; Nutakki Anusha; Bollikolla Hari Babu; Syed Farooq Adil; Mohammed Rafi Shaik; Mujeeb Khan; Abdulrahman Al-Warthan; Osamah Alduhaish; M. Mujahid Alam
A new series of coumarin-yl-chalcone derivatives (3a-m) had been designed and synthesized through different reactions such as aromatic addition, cyclization and Claisen-Schmidt reactions in good yields (54–78%). 5-acetyl-4-(2-hydroxyphenyl) -6-methyl-3, 4-dihydropyrimidin-2(1H) -one (1) has been synthesized by multi-component one pot reaction of salicylaldehyde, methyl acetoacetate and urea, which
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Polychromatic luminescence and improved antifungal performance of succinic acid in the lattice of L-Lysine monohydrochloride Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-24 B. Aneeba; S.V. Ashvin Santhia; R. Sheela Christy; Fahad A. Al-Misned; Hamed A. El-Serehy; S. Vinu
The incorporation of succinic acid (SA) in the lattice of L-Lysine monohydrochloride (LM) has opened the new avenue in the field of production and application of scintillator materials such as LED and antifungal drug. Crystalline trait and monoclinic structure were scanned by XRD. The existence of carbonyl, carboxylate and protonated amine group were confirmed through FTIR and UV spectra predicted
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In-silico protein-ligand docking studies against the estrogen protein of breast cancer using pharmacophore based virtual screening approaches Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-22 Jesudass Joseph Sahayarayan; Kulanthaivel Soundar Rajan; Ramasamy Vidhyavathi; Mutharasappan Nachiappan; Dhamodharan Prabhu; Saleh Alfarraj; Selvaraj Arokiyaraj; Amalorpavanaden Nicholas Daniel
Breast cancer in woman is the most common cancer and in 2018 there were around 2 million new cases recorded. The maximum rate of breast cancer is reported in Belgium followed by Luxembourg. It is the second most general cancer, Lung cancer being the first. If the cancer tumor is located only in the breast, the survival rate would be 99%. If the tumor has wide to lymph nodes around the survival rate
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Nutritional and toxic elemental analysis of dry fruits using laser induced breakdown spectroscopy (LIBS) and inductively coupled plasma atomic emission spectrometry (ICP-AES) Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-27 I. Rehan; M.A. Gondal; M.A. Almessiere; R.A. Dakheel; K. Rehan; S. Sultana; M.A. Dastageer
Quantitative investigation of essential and trace heavy elements present in health-beneficial dry fruits (Pistachio, Almonds, Black walnut, White walnut, and Cashew) was investigated using Laser Induced Breakdown Spectroscopy. For an accurate elemental exposure using LIBS technique, the local thermo-dynamical equilibrium of the laser induced plasma was established and verified using McWhirter criterion
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Isolation of diverse bioactive compounds from Euphorbia balsamifera: Cytotoxicity and antibacterial activity studies Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-27 Salha M Aljubiri; Samir A. Mahgoub; Abdulrahman I. Almansour; Mohamed Shaaban; Kamel H. Shaker
Antibacterial and cytotoxic activities of Euphorbia balsamifera, fractions and pure compounds were evaluated. The cytotoxic assays for HCT116, HePG2 and MCF7 showed a significant IC50: 54.7 and 76.2 µg/mL of non-polar fraction “n-hexane” against HCT116 and HePG2, respectively. Antibacterial results revealed that plant fractions exhibited significant potential against the tested pathogens than the total
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Psidium guajava Linn leaf ethanolic extract: In vivo giardicidal potential with ultrastructural damage, anti-inflammatory and antioxidant effects Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-27 Safaa I. Khedr; El Hassan M. Mokhamer; Amal A.A. Hassan; Asmaa S. El-Feki; Gihan M. Elkhodary; Mohamed S.A. El-Gerbed
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Ginger extract attenuates labetalol induced apoptosis, DNA damage, histological and ultrastructural changes in the heart of rat fetuses Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-27 Hend T. El-Borm; Marwa S. Gobara; Gamal M. Badawy
Labetalol is a medication used to treat maternal hypertension during pregnancy. However, it is often associated with many side effects. Recently, several studies have been focused on the protective effect of medicinal plant extracts, such as ginger, against drugs inducing toxicity. Therefore, it has been hypothesized that ginger aqueous extraction can ameliorate labetalol-induced histological, ultrastructural
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Computational selection of flavonoid compounds as inhibitors against SARS-CoV-2 main protease, RNA-dependent RNA polymerase and spike proteins: A molecular docking study Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-22 Marimuthu Ragavan Rameshkumar; Purushothaman Indu; Narasingam Arunagirinathan; Babu Venkatadri; Hamed A. El-Serehy; Ajaz Ahmad
An outbreak of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has been recognized as a global health concern. Since, no specific antiviral drug is proven effective for treatment against COVID-19, identification of new therapeutics is an urgent need. In this study, flavonoid compounds were analyzed for its inhibitory potential against important protein targets of SARS-CoV-2 using computational
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Antimicrobial activity of polyphenolic compounds from Spirulina against food-borne bacterial pathogens Saudi J. Biol. Sci. (IF 2.802) Pub Date : 2020-10-27