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Diversity and genetic characterization of Chlamydia isolated from Siamese crocodiles (Crocodylus siamensis) Acta Trop. (IF 2.7) Pub Date : 2024-03-12 Somjit Chaiwattanarungruengpaisan, Metawee Thongdee, Nlin Arya, Weena Paungpin, Wanna Sirimanapong, Ladawan Sariya
Chlamydiosis, an infection caused by several species, has been reported in Nile, saltwater, and Siamese crocodiles. Despite its widespread reports in various countries, including Thailand, genetic information on species remains limited. This study presents a whole-genome-based characterization of Siamese crocodile-isolated . The results showed that Siamese crocodile contained a single circular chromosome
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A Prospects Tool in Virus Research: Analyzing the Applications of Organoids in Virus Studies Acta Trop. (IF 2.7) Pub Date : 2024-03-11 Qi Shen, Yu-han Zhou, Yan-qiu Zhou
Organoids have emerged as a powerful tool for understanding the biology of the respiratory, digestive, nervous as well as urinary system, investigating infections, and developing new therapies. This article reviews recent progress in the development of organoid and advancements in virus research. The potential applications of these models in studying virul infections, pathogenesis, and antiviral drug
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Molecular survey of feline immunodeficiency virus (FIV) infection in Namibian cats Acta Trop. (IF 2.7) Pub Date : 2024-03-11 Giovanni Franzo, Lourens de Villiers, Lauren M. Coetzee, Mari de Villiers, Umberto Molini
Feline Immunodeficiency Virus (FIV) is one of the most important infectious diseases of cats, with potential implications in wildlife conservation. Unfortunately, FIV screening and surveillance in domestic cats remains limited in several African countries, including Namibia. In this study, 279 blood samples from domestic cats in Namibia were analyzed for FIV diagnosis by PCR. The cats represented various
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Spatial analysis of food and water-borne diseases in Ahmedabad, India: Implications for urban public health planning Acta Trop. (IF 2.7) Pub Date : 2024-03-11 Ayushi Sharma, Bima Sakti Satria Wibawa, Gerry Andhikaputra, Bhavin Solanki, Amir Sapkota, Lin-Han Chiang Hsieh, Veena Iyer, Yu-Chun Wang
Spatial analysis of infectious diseases can play an important role in mapping the spread of diseases and can support policy making at local level. Moreover, identification of disease clusters based on local geography and landscape forms the basis for disease control and prevention. Therefore, this study aimed to examine the spatial-temporal variations, areas, and potential risk factors of infectious
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Monitoring Aedes populations for arboviruses, Wolbachia, insecticide resistance and its mechanisms in various agroecosystems in Benin Acta Trop. (IF 2.7) Pub Date : 2024-03-08 S. Ateutchia-Ngouanet, F. Nanfack-Minkeu, K. Mavridis, S. Wanji, M. Demanou, J. Vontas, R. Djouaka
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Community-based symptom reporting among agro-pastoralists and their livestock in Chad in a One Health approach. Acta Trop. (IF 2.7) Pub Date : 2024-03-07 Camille Doras, Ranya Özcelik, Mahamat Fayiz Abakar, Ramadan Issa, Pidou Kimala, Soumaya Youssouf, Isabelle Bolon, Salome Dürr
One Health Syndromic Surveillance has a high potential for detecting early epidemiological events in remote and hard-to-reach populations. Chadian pastoralists living close to their animals and being socio-economically unprivileged have an increased risk for zoonosis exposure. Engaging communities in disease surveillance could also strengthen preparedness capacities for outbreaks in rural Chad. This
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Exploring the impact of socioeconomic and natural factors on pulmonary tuberculosis incidence in China (2013–2019) using explainable machine learning: A nationwide study Acta Trop. (IF 2.7) Pub Date : 2024-03-07 Yiwen Tao, Jiaxin Zhao, Hao Cui, Lili Liu, Long He
Pulmonary tuberculosis (PTB) stands as a significant and prevalent infectious disease in China. Integrating 13 natural and socioeconomic factors, we conduct nine machine learning (ML) models alongside the Tree-Structured Parzen Estimator to predict the monthly PTB incidence rate from 2013 to 2019 in mainland China. With explainable ML techniques, our research highlights that population size, per capita
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First experimental observation on biology of the avian malaria parasite Plasmodium (Novyella) homonucleophilum (lineage pSW2), with remarks on virulence and distribution Acta Trop. (IF 2.7) Pub Date : 2024-03-06 Gediminas Valkiūnas, Mikas Ilgūnas, Carolina Hernández-Lara, Mélanie Duc, Tatjana Iezhova
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Population genetic structure and wing geometric morphometrics of the filarial vector Armigeres subalbatus (Diptera: Culicidae) in Thailand Acta Trop. (IF 2.7) Pub Date : 2024-03-05 Sedthapong Laojun, Tanasak Changbunjong, Tanawat Chaiphongpachara
(Diptera: Culicidae) is a mosquito species of significant medical and veterinary importance. It is widely distributed across Southeast and East Asia and is commonly found throughout Thailand. This study assessed the genetic diversity and population structure of in Thailand using the cytochrome oxidase subunit I () gene sequences. Additionally, wing shape variations among these populations were examined
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Pharmacological potential of limonene against opportunistic fungi: Impact on Candida virulence Acta Trop. (IF 2.7) Pub Date : 2024-03-01 Maria Hellena Garcia novais, Naiza Saraiva farias, Andressa Guilhermino Dos santos, Victor Juno Alencar fonseca, Jaime Ribeiro-Filho, Irwin Rose Alencar De menezes, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga
The present article aims to evaluate the antifungal and antivirulence effect of the phytoconstituent Limonene against spp. Antifungal assays were performed, where the concentration capable of inhibiting 50 % of fungal growth, the growth inhibition curve, the minimum fungicidal concentration, the evaluation of the modifying effect with fluconazole, the inhibitory effect of the substances on the morphological
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Spatial distribution of Triatoma dimidiata peridomestic colonies modulated by distance between susceptible microhabitat patches Acta Trop. (IF 2.7) Pub Date : 2024-03-01 Daniel Chan-Espinoza, Hugo A. Ruiz-Piña, Elsy B. Canché-Pool, Enrique Reyes-Novelo
is a vector of the hemoparasite , the causal agent of Chagas disease. It settles reproductive colonies in the peridomicile of the premises. The peridomicile is comprised of a random set of artificial and natural features that overlap and assemble a network of microenvironmental suitable sites (patches) that interact with each other and favor the structure and proliferation of colonies. The heterogeneity
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Scorpion envenomation in Brazil and its relationship with the social determinants of health: A population-based ecological study Acta Trop. (IF 2.7) Pub Date : 2024-02-29 Thayane Santos Siqueira, Adriano José dos Santos, João Lucas Cavalcante Santos, Rikelly Rhuana Nunes da Silva, José Rodrigo Santos Silva, Victor Santana Santos
This study comprehensively analyzed cases of scorpion envenomation in Brazil, exploring the temporal trends and geographic patterns of such incidents between January 1, 2012, and December 31, 2022. Simultaneously, we assessed the correlation between scorpion envenomation and social determinants of health and social vulnerability. We conducted a population-based ecological study, gathering information
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Diversity response of necrophagous dipteran communities and their functional groups to an anthropization gradient Acta Trop. (IF 2.7) Pub Date : 2024-02-29 Matias Ignacio Dufek, Dario Daniel Larrea, Miryam Pieri Damborsky, Pablo Ricardo Mulieri
Anthropization impacts on biodiversity and functional groups of necrophagous flies in Chaco, Argentina: Ecological, public health, and forensic entomology implications.
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Molecular Detection and Characterization of Coxiella burnetii in Aborted Samples of Livestock in China Acta Trop. (IF 2.7) Pub Date : 2024-02-28 Ping Liu, JinYan Wu, Weimin Ma, Yamin Yang, Lv Lv, Jiang Cai, Zhijie Liu, Jijun He, Youjun Shang, Zhaocai Li, Xiaoan Cao
is the causative agent of zoonotic Q fever. Animals are the natural reservoirs of , and domestic livestock represent the major sources of human infection. infection in pregnant females may causes abortion during late pregnancy, whereby massive shedding of with abortion products becomes aerosolized and persists in the environment. Therefore, monitoring and surveillance of this infection in livestock
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A Hidden Dilemma; Post COVID-19 First Detection of Varicella zoster M4 Genotype from Pakistan Acta Trop. (IF 2.7) Pub Date : 2024-02-28 Saba Hanif, Sarah Johnson, Maryam Siddique, Muhammad Salman, Muhammad Suleman Rana, Shawana Sharif, Rani Faryal
During the COVID-19 pandemic, the risk of childhood infectious diseases was increased. Post-COVID-19 escalation of chickenpox cases, becoming an emerging public health concern. Thus, the study was designed to compare chickenpox prevalence and virus (VZV) genotypes circulating before, during, and post-COVID-19 in Pakistan. A total of 267 lesion specimens collected from tertiary care hospitals, and chickenpox
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Effectiveness evaluation of mosquito suppression strategies on dengue transmission under changing temperature and precipitation Acta Trop. (IF 2.7) Pub Date : 2024-02-25 Kaihui Liu, Shuanghui Fang, Qiong Li, Yijun Lou
Widespread resurgence of dengue outbreaks has seriously threatened the global health. Due to lack of treatments and vaccines, one key strategy in dengue control is to reduce the vector population size. As an environment-friendly mosquito control approach, releasing male mosquitoes transinfected with specific strain into the field to suppress the wild mosquito population size has become wildly accepted
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Widespread distribution of human-infective Enterocytozoon bieneusi genotypes in small rodents in northeast China and phylogeny and zoonotic implications revisited Acta Trop. (IF 2.7) Pub Date : 2024-02-24 Shuning Jiang, Shui Yu, Yaoyu Feng, Longxian Zhang, Monica Santin, Lihua Xiao, Wei Li
features high genetic diversity among host species and environmental sources and over 500 genotypes in 11 phylogenetic groups have been defined. Here we investigated 291 small rodents in Heilongjiang province, northeast China, for the presence of by PCR of the ribosomal internal transcribed spacer (ITS). Nine of 60 (15.0%) gray squirrels from a park in Harbin, 120 of 201 (59.7%) guinea pigs from a
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Virome analyses of Amblyomma cajennense and Rhipicephalus microplus ticks collected in Colombia Acta Trop. (IF 2.7) Pub Date : 2024-02-23 Katterine Molina-Hoyos, Carolina Montoya-Ruíz, Patricia V. Aguilar, Alveiro Pérez-Doria, Francisco J. Díaz, Juan D. Rodas
Tick-borne viruses (TBV) have gained public health relevance in recent years due to the recognition of human-associated fatal cases and the increase in tick-borne disease and transmission. However, many tick species have not been studied for their potential to transmit pathogenic viruses, especially those found in Latin America. To gain better understanding of the tick virome, we conducted targeted
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In vitro evaluation of the susceptibility of bacterial biofilms to Hecogenin Acetate Acta Trop. (IF 2.7) Pub Date : 2024-02-22 Nara Juliana Santos Araújo, Maria do Socorro Costa, Ana Raquel Pereira da Silva, Cícera Laura Roque Paulo, Camila Aparecida Pereira Silva, Franceildo Jorge Felix, Cicera Datiane de Morais Oliveira-Tintino, José Maria Barbosa Filho, Thiago Sampaio de Freitas, Maria Flaviana Bezerra Morais Braga, Henrique Douglas Melo Coutinho, Jacqueline Cosmo Andrade-Pinheiro
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Multi-locus sequence analysis of ‘Candidatus Mycoplasma haematomacacae’ in free-ranging macaques from Thailand suggestive of a closer relationship to hemotropic mycoplasmas in capuchins and potential origin from bats Acta Trop. (IF 2.7) Pub Date : 2024-02-20 Duriyang Narapakdeesakul, Mutchamon Kaewparuehaschai, Salintorn Thongsahuan, Paisin Lekcharoen, Theerakamol Pengsakul, Sittiporn Pattaradilokrat, Morakot Kaewthamasorn
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Thinking green: Insecticidal effect of biorational solutions against Triatoma pallidipennis Stal (Hemiptera: Triatominae) Acta Trop. (IF 2.7) Pub Date : 2024-02-19 Reyna Vargas-Abasolo, José D. Rivera-Duarte, Víctor Manuel Almaraz-Valle, Mario Mejia-Mandujano, Liliana Aguilar-Marcelino, Alex Córdoba-Aguilar
The control of triatomine vectors depends almost exclusively on conventional insecticides. These compounds can, nevertheless, cause negative effects on environmental and human health as well as induce resistance in triatomines. Therefore, we need to look for more sustainable alternatives. is one of the main chagasic vectors in Mexico. We evaluated the insecticidal effectiveness of two oils (neem and
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Galectin-3 (Gal-3) and the tissue inhibitor of matrix metalloproteinase (TIMP-2) as potential biomarkers for the clinical evolution of chronic Chagas cardiomyopathy Acta Trop. (IF 2.7) Pub Date : 2024-02-17 Cristiane Alves da Silva Menezes, Ana Laura Grossi de Oliveira, Isabela Cristina Magalhães Barbosa, Augusto César Parreiras de Jesus, Ana Thereza Chaves, Manoel Otávio da Costa Rocha
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Molecular characterization of Haemoproteus enucleator with emphasis on the host and geographic distribution Acta Trop. (IF 2.7) Pub Date : 2024-02-17 Mélanie Tchoumbou, Josef Harl, Aladji Souaibou, Tatjana Iezhova, Gediminas Valkiūnas
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Unveiling of the antileishmanial activities of Linalool loaded zinc oxide nanocomposite through its potent antioxidant and immunomodulatory effects Acta Trop. (IF 2.7) Pub Date : 2024-02-17 Aishah E Albalaw, Abdullah F Shater, Abdullah D Alanazi, Hamdan I Almohammed
This study aimed to produce linalool loaded zinc oxide nanocomposite (LZNPs) and assess its and antileishmanial effects against LZNPs was produced through the synthesis of an ethanolic solution containing polyvinyl alcohol. The average size of LZNPs was determined to be 105 nm. The findings indicated that LZNPs displayed significant (p<0.01) antileishmanial effects on promastigotes and amastigotes
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Molecular phylogenetic analysis of Echinococcus granulosus sensu lato infecting sheep in Italy Acta Trop. (IF 2.7) Pub Date : 2024-02-16 Piero Bonelli, Elisa Serra, Silvia Dei Giudici, Angela Peruzzu, Silvia Crotti, Patrizia Danesi, Andrea Carvelli, Toni Piseddu, Giovanna Masala
Cystic Echinococcosis (CE), caused by the larval form of , is a neglected zoonosis still threatening public health worldwide. In Italy different epidemiological scenarios were reported depending on the geographical area and associated socio-economic activities. Although in northern Italy the occurrence of is considered sporadic, in the southern regions and, particularly in Sardinia, CE prevalence reaches
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The involvement of cytokine gene polymorphism in determining the vulnerability to Blastocystis and Helicobacter pylori co-infection in the Egyptian population Acta Trop. (IF 2.7) Pub Date : 2024-02-15 Asmaa Ibrahim, Nancy O. Kamel, Fatma Rageh, Rasha Elgamal, Bassam Mansour salama, Mohamed A. Sakr, Mohamed Mahmoud Elhoseeny, Eman Medhat Ahmed Osman, Samar Sayed, Manar Ezzelarab Ramadan
The present study aimed to identify any potential association between IL-1β and TNF-α gene polymorphism and the risk of infection as well as co-infection of with (). A total of 314 stool samples were collected and examined microscopically for the detection of parasitic infection. DNA was extracted from all samples and utilized to identify molecularly. Positive samples were used for detection by rapid
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RNA interference of NADPH cytochrome P450 increased deltamethrin susceptibility in a resistant strain of the Chagas disease vector Triatoma infestans Acta Trop. (IF 2.7) Pub Date : 2024-02-13 Gonzalo M. Varela, Beatriz A. García, María M. Stroppa
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Aedes aegypti oviposition dynamics in towns with low human population density in yungas and dry chaco, Salta, Argentina Acta Trop. (IF 2.7) Pub Date : 2024-02-13 Mariana M. Chanampa, Juan Pablo Aparicio, Soledad Hodi, Enrique Derlindati, Nicolas Rodriguez, Roxana Alejandra García Larsen, Raquel M. Gleiser
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Gallium maltolate, a promising low toxicity drug with curative effect on mice chronically infected with Trypanosoma evansi Acta Trop. (IF 2.7) Pub Date : 2024-02-12 Luciana Dalla Rosa, Camila Belmonte Oliveira, Beni Jequicene Mussengue Chaúque, Thirssa Helena Grando, Lucas Trevisan Gressler, Nathieli Bottari, Silvia Gonzalez Monteiro
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First winter record of Latrodectus mirabilis (Araneae: Theridiidae) in arid Patagonia: A consequence of climate change and urbanization? Acta Trop. (IF 2.7) Pub Date : 2024-02-10 Facundo Tomas Zaffaroni, Alejandra Esther Sandoval, Gerardo Aníbal Marti, Germán Horacio Cheli
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Dietary glycemic and energy load differentially modulates Schistosoma mansoni-induced granulomatous inflammation and response to antiparasitic chemotherapy Acta Trop. (IF 2.7) Pub Date : 2024-02-10 Luis F.C. Dos Reis, Cláudio D. Cerdeira, Laís C.C. Silva, Amanda B.S.B. Ramos, José Edson C. Silva, Aline P. Castro, Renato R. Ventura, Raquel L.M. Souza, Marcos J. Marques, Rômulo D. Novaes
The impact of diet composition and energy content on schistosomiasis evolution and treatment efficacy is still controversial. This study compared the impact of sucrose-rich diet and intermittent fasting on infection and praziquantel (PZQ)-based chemotherapy response in mice. BALB/c mice were infected with and followed for 15 weeks. The animals were randomized into nine groups receiving high glycemic
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Mayaro virus infection elicits a robust pro-inflammatory and antiviral response in human macrophages Acta Trop. (IF 2.7) Pub Date : 2024-02-09 Lady Johana Hernández-Sarmiento, Y.S. Tamayo-Molina, Juan Felipe Valdés-López, Silvio Urcuqui-Inchima
Mayaro virus (MAYV), the etiological agent of Mayaro fever (MAYF), is an emergent arbovirus pathogen belonging to family. MAYF is characterized by high inflammatory component that can cause long-lasting arthralgia that persists for months. Macrophages are viral targets and reservoirs, key components of innate immunity and host response. Given the importance of this pathogen, our aim was to determine
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Intestine proteomic and metabolomic alterations in dogs infected with Toxocara canis Acta Trop. (IF 2.7) Pub Date : 2024-02-08 Na Wang, Soben Sieng, Tian Liang, Jingyun Xu, Qian Han
Toxocariasis is an important zoonotic parasitic disease. adults live and reproduce in the intestinal tract of dogs and other canine hosts, and the infectious eggs are continuously excreted in feces, which causes environmental contamination and has an important public health significance. In this study, TMT proteomic and untargeted metabolomic methods were used to explore the physiological and pathological
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Population genetics and genomics of Triatoma brasiliensis (Hemiptera, Reduviidae) in an area of high pressure of domiciliary infestation in Northeastern Brazil Acta Trop. (IF 2.7) Pub Date : 2024-02-07 Maria Carolina Viana, Alessandro Alves-Pereira, Marcelo A P Oliveira, Carolina Valença-Barbosa, Elaine Folly-Ramos, Anete P Souza, Daniela M Takiya, Carlos E Almeida
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Malacological, socio-environmental evaluation, and evidence of local transmission and maintenance of schistosomiasis in an urban area of Northeast Brazil Acta Trop. (IF 2.7) Pub Date : 2024-02-07 Elainne Christine de Souza Gomes, Iris Edna Pereira da Silva, Hallysson Douglas Andrade de Araújo, Constança Simões Barbosa
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Quinine and chloroquine: Potential preclinical candidates for the treatment of tegumentary Leishmaniasis Acta Trop. (IF 2.7) Pub Date : 2024-02-06 Norton Rubens Diunior Lucas Pejara Rossi, Saara Neri Fialho, Aurileya de Jesus Gouveia, Amália Santos Ferreira, Minelly Azevedo da Silva, Leandro Do Nascimento Martinez, Welington da Silva Paula do Nascimento, Arlindo Gonzaga Jr, Daniel Sol Sol de Medeiros, Neuza Biguinati de Barros, Rita de Cássia Alves, Giselle Martins Gonçalves, Carolina Garcia Bioni Teles
leishmaniasis is an endemic disease in more than 90 countries, constituting a relevant public health problem. Limited treatment options, increase in resistance, and therapeutic failure are important aspects for the discovery of new treatment options. Drug repurposing may accelerate the discovery of antileishmanial drugs. Recent tests indicating the potential of antimalarials resulted in the design
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Novel herpesvirus in the critically endangered Galapagos pink land iguana Acta Trop. (IF 2.7) Pub Date : 2024-02-03 Ainoa Nieto-Claudín, Carlos Sacristán, Sharon L. Deem, Gregory A. Lewbart, Giuliano Colosimo, Fernando Esperón, Christian Sevilla, Gabriele Gentile
Virus surveillance in wildlife is important to understand ecosystem health, taxonomy, and evolution. Nevertheless, viruses in reptiles, and specifically in squamates, continue to be understudied. Herein, we conducted a health assessment on the critically endangered Galapagos pink land iguana () and the vulnerable Galapagos land iguana (). We collected oral and/or cloacal swabs from 47 clinically healthy
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Effect of an altitudinal gradient on the morphology, molecular identification and distribution of Rhipicephalus linnaei in Veracruz, Mexico Acta Trop. (IF 2.7) Pub Date : 2024-02-03 Pamela Aguilar-Meraz, David A. Moo-Llanes, Sokani Sánchez-Montes, Ana C. Montes de Oca-Aguilar, Dora Romero-Salas, Anabel Cruz-Romero, Karla M. López-Hernández, Sergio E. Bermúdez-Castillero, Mariel Aguilar-Domínguez
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Geometry of posterior larval spiracles to identify medically and forensically important calliphorids in Thailand Acta Trop. (IF 2.7) Pub Date : 2024-02-03 Wanida Kanta, Kwankamol Limsopatham, Kabkaew L. Sukontason, Kom Sukontason, Jean-Pierre Dujardin, Sebastien Dujardin, Sangob Sanit
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Antimicrobial, toxicological, and antigenic characteristics of three scorpion venoms from Colombia: Centruroides margaritatus, Tityus pachyurus and Tityus n. sp. aff. metuendus Acta Trop. (IF 2.7) Pub Date : 2024-01-28 Leydy Lorena Mendoza-Tobar, Herlinda Clement, Ivan Arenas, Jimmy Alexander Guerrero-Vargas, Lorena Hernandez-Orihuela, Samuel Cardoso-Arenas, Juan Carlos Sepulveda-Arias, Gerardo Corzo
The venom fractions of three buthid scorpion species from Colombia, C. margaritatus, T. pachyurus and T. n. sp. aff. metuendus, were examined for antimicrobial and toxicity toward mice and insects. The three venoms were separated into individual fractions using RP-HPLC, resulting in 85 fractions from C. margaritatus, 106 from T. pachyurus, and 70 from T. n. sp. aff. metuendus. The major fractions from
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First molecular detection and characterization of Enterocytozoon bieneusi different genotypes in human patients from Italy Acta Trop. (IF 2.7) Pub Date : 2024-01-29 Isabel Guadano-Procesi, Federica Berrilli, David Di Cave
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Environmental relationships and anthrax epidemiology: field experiences of host resistance as opposed to dose-dependent experiments Acta Trop. (IF 2.7) Pub Date : 2024-02-02 Domenico Galante, Robert S. Gainer, Martin E. Hugh-Jones
Even though anthrax is a disease of antiquity that has been studied for centuries, serious concerns have been raised about our understanding of its epidemiology. Since the 1960s, we have based the epidemiology of anthrax on the results of dose-dependent experiments, especially those involving cattle at that time. In this species the experiments demonstrated that the severity of infection was dependent
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Clotrimazole causes membrane depolarization and induces sub G0 cell cycle arrest in Leishmania donovani Acta Trop. (IF 2.7) Pub Date : 2024-02-01 Anindita Paul, Pradyot Kumar Roy, Neerupudi Kishore Babu, Sushma Singh
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Molecular and next-generation sequencing analysis of tick-borne pathogens of Rhipicephalus ticks (Acari: Ixodidae) in cattle and dogs Acta Trop. (IF 2.7) Pub Date : 2024-02-01 Jitrawadee Intirach, Xin Lv, Nataya Sutthanont, Benchi Cai, Danita Champakaew, Tao Chen, Qian Han, Zhiyue Lv
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INTRANASAL DELIVERY OF LaAg VACCINE IMPROVES IMMUNITY OF AGED MICE AGAINST VISCERAL LEISHMANIASIS Acta Trop. (IF 2.7) Pub Date : 2024-01-26 CAIO LOUREIRO SALGADO, ANDRÉS FELIPE MENDÉZ COREA, LUCIANA POLACO COVRE, ALESSANDRA MARCIA FONSECA-MARTINS, ALOISIO FALQUETO, HERBERT LEONEL DE MATOS GUEDES, BARTIRA ROSSI-BERGMANN, DANIEL CLÁUDIO OLIVIERA GOMES
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Effect of environmental variables on the incidence of Visceral Leishmaniasis in Brazil and Colombia Acta Trop. (IF 2.7) Pub Date : 2024-01-26 Juan David Gutiérrez, Mariano Altamiranda-Saavedra, Julián Ávila-Jiménez, Iris Amati Martins, Flávia Virginio
Visceral Leishmaniasis (VL) is the most severe of the three forms of Leishmaniasis. In the Americas, Brazil and Colombia present more than 90% of the cases in the region. Our aim in this research was to estimate the association of the incidence rate of Visceral Leishmaniasis with the following environmental variables: the percentage of area suitable for the vector Lutzomyia longipalpis, the episodes
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Theileria annulata subtelomere-encoded variable secreted protein-TA05560 interacts with bovine RNA binding motif protein 39 (RBM39) Acta Trop. (IF 2.7) Pub Date : 2024-01-26 Quanying Ma, Yuan Han, Yong Fu, Guixiang Teng, Xiaoqiang Wang, Junlong Liu, Zhi Li
Theileria annulata is the only eukaryotic pathogen able to transform bovine leukocytes, including B cells, macrophages and dendritic cells. T. annulata-transformed cells exhibit several cancer-like phenotypes, such as hyperproliferation, immortalization and dissemination. Although several parasite factors involved in bovine cell transformation have been explored, the roles of subtelomere-encoded variable
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Molecular detection and characterization of Bartonella spp. in small mammals in the Amazonia and Cerrado biomes, midwestern Brazil Acta Trop. (IF 2.7) Pub Date : 2024-01-23 Thábata dos Anjos Pacheco, Renan Bressianini do Amaral, Priscila Ikeda, Maerle Oliveira Maia, Daniel Antônio Braga Lee, Thiago Borges Fernandes Semedo, Ravena Fernanda Braga de Mendonça, Fernando Pedroni, Maurício Claudio Horta, Rogério Vieira Rossi, Marcos Rogério André, Richard de Campos Pacheco
Although Bartonella spp. have been worldwide described in rodents and bats, few studies have reported these agents in marsupials. The present work aimed to investigate the occurrence and genetic diversity of Bartonella in small mammals (rodents, marsupials, and bats) and associated ectoparasites in two ecoregions (Amazonia and Cerrado biomes) in midwestern Brazil. For this purpose, DNA samples from
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A bipolar intuitionistic fuzzy decision-making model for selection of effective diagnosis method of tuberculosis Acta Trop. (IF 2.7) Pub Date : 2024-01-26 Ezhilarasan Natarajan, Felix Augustin, Ranganathan Saraswathy, Samayan Narayanamoorthy, Soheil Salahshour, Ali Ahmadian, Daekook Kang
Objectives: Tuberculosis (TB) is a contagious illness caused by Mycobacterium tuberculosis. The initial symptoms of TB are similar to other respiratory illnesses, posing diagnostic challenges. Therefore, the primary goal of this study is to design a novel decision-support system under a bipolar intuitionistic fuzzy environment to examine an effective TB diagnosing method. Methods: To achieve the aim
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Modelling of tuberculosis dynamics incorporating indirect transmission of contaminated environment and infectivity of smear-negative individuals: a case study for Xinjiang, China Acta Trop. (IF 2.7) Pub Date : 2024-01-24 Chunjie Gao, Tao Zhang, Ying Liao, Yingdan Wang, Haiyan Jiao, Mengjuan Wu, Qianqian Cui, Kai Wang, Lei Wang
Xinjiang has been one of the high incidence areas of pulmonary tuberculosis (PTB) in China. Besides being infected by direct contacting with active PTB individuals (direct infection), the susceptible would be infected because of the exposure to the environment contaminated by Mycobacterium tuberculosis (indirect infection). Active PTB individuals include not only the smear-positive PTB (PTB+) but also
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Generation of IgG antibodies against Strongyloides stercoralis in mice via immunization with recombinant antigens A133 and Ss-IR Acta Trop. (IF 2.7) Pub Date : 2024-01-20 Matthew Tze Jian Wong, Nor Suhada Anuar, Rahmah Noordin, Gee Jun Tye
Strongyloidiasis, caused by the nematode Strongyloides stercoralis, remains a threat to global public health, and a vaccine would be useful to control the disease, especially in developing countries. This study aimed to evaluate the efficacy of recombinant proteins, A133 and Ss-IR, as potential vaccine candidates against strongyloidiasis by investigating the humoral and cellular immune responses in
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Molecular discrimination of G1 and G3 genotypes of Echinococcus granulosus sensu stricto obtained from human, cattle, and sheep using the mitochondrial NADH dehydrogenase subunit 5 marker Acta Trop. (IF 2.7) Pub Date : 2024-01-21 Figen Celik, Muhammed Ahmed Selcuk, Seyma Gunyakti Kilinc, Harun Kaya Kesik, Haroon Ahmed, Ying Wang, Sami Simsek, Jianping Cao
Cystic echinococcosis (CE) is a common zoonotic disease caused by the larval form of Echinococcus granulosus sensu lato. This study determined the genotype and haplotype differences using the NADH dehydrogenase subunit 5 gene in hydatid cyst samples. Human (n = 12), cattle (n = 28), and sheep (n = 31) hydatid cyst isolates were included. Seventy-one genomic DNA samples were successfully extracted,
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Toxoplasma gondii: Seroprevalence and association with childhood brain tumors in Egypt Acta Trop. (IF 2.7) Pub Date : 2024-01-17 Marwa M. Hamouda, Amany S. El-Saied, Ahmed Zaher, Amr Farid Khalil, Ayat A. ElBlihy, Nairmen Nabih, Samar N. El-Beshbishi
Background Childhood brain tumors are a significant global health challenge, yet the etiology of these tumors remains elusive. While research has identified potential risk factors, recent studies have explored the involvement of infectious agents, particularly Toxoplasma gondii (T. gondii), in brain tumor development. Methods This study aimed to explore the prevalence of T. gondii infection in children
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Merging socioecological variables to predict risk of Chagas disease Acta Trop. (IF 2.7) Pub Date : 2024-01-11 Maya Rocha-Ortega, Angela Nava-Bolaños, Alex Córdoba-Aguilar
How far are we from predicting the occurrence of zoonotic diseases? In this paper we have made use of both socioecological and ecological variables to predict Chagas disease occurrence. Chagas disease involves, Trypanosoma cruzi, a complex life-cycle parasite which requires two hosts: blood-feeding triatomine insects and vertebrate hosts including humans. We have used a common risk assessment method
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A visualized hybrid PCR-LAMP assay for the detection of human Plasmodium species Acta Trop. (IF 2.7) Pub Date : 2024-01-09 Meng Yee Lai, Sasheela Sri La Sri Ponnampalavanar, Sharifah Faridah Syed Omar, Yee Ling Lau
Combining the advantages of PCR and LAMP, we described a new technique, namely PCR-LAMP, for malaria diagnosis. The whole process of DNA amplification can be completed in 35 min. This hybrid amplification technique markedly improved the sensitivity of detection compared to the classic single PCR or LAMP assay alone. PCR-LAMP assay had a detection limit of 1 copy/µL for P. knowlesi and P. ovale, 0.1
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Analysis of liver fibrosis equations as a potential role of predictive models in Crimean-Congo hemorrhagic fever Acta Trop. (IF 2.7) Pub Date : 2024-01-11 Serkan Bolat, Seyit Ali Büyüktuna, Funda İpekten, Kübra Doğan, Gökmen Zararsız, Halef Okan Doğan
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Risk of a vector-borne endemic zoonosis for wildlife: Hosts, large-scale geography, and diversity of vector-host interactions for Trypanosoma cruzi Acta Trop. (IF 2.7) Pub Date : 2024-01-04 Laura Rengifo-Correa, Ángel Rodríguez-Moreno, Ingeborg Becker, Jorge Abelardo Falcón-Lezama, Roberto Tapia-Conyer, Sokani Sánchez-Montes, Gerardo Suzán, Christopher R. Stephens, Constantino González-Salazar
Drivers for wildlife infection are multiple and complex, particularly for vector-borne diseases. Here, we studied the role of host competence, geographic area provenance, and diversity of vector-host interactions as drivers of wild mammal infection risk to Trypanosoma cruzi, the aetiological agent of Chagas disease. We performed a systematic sampling of wild mammals in 11 states of Mexico, from 2017
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The burden of intestinal parasitic infections in Antioquia, Colombia: Impact in childhood growth development and nutritional status Acta Trop. (IF 2.7) Pub Date : 2024-01-07 Carolina Hernández-Castro, Sonia del Pilar Agudelo-López, Angélica Patricia Medina-Lozano, Diego López-García, Luis Alfonso García-Tuberquia, Jorge Humberto Botero-Garcés, María Cenelia Orozco-Peláez, Manuela Bolaños-Muñoz, Daniel Antonio Bejarano-Villafañe, David Carmena
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From molecules to ecosystems: Insights into a network of interactions for a Chagas disease outbreak using Triatoma brasiliensis as natural samplers Acta Trop. (IF 2.7) Pub Date : 2024-01-07 Carlos E. Almeida, Milena M. Máximo, Dayane Pires-Silva, Daniela M. Takiya, Carolina Valença-Barbosa, Maria C. Viana, Carolina Reigada, Alena M. Iñiguez, Myriam Harry, Elaine Folly-Ramos
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LdCyPA attenuates MAPK pathway to assist Leishmania donovani immune escape in host cells Acta Trop. (IF 2.7) Pub Date : 2024-01-07 Shuangshuang Yin, Jiao Li, Jianping Chen, Qi Zhou, Deng bin pei Duan, Meng Lai, Junchao Zhong, Jinlei He, Dali Chen, Zheng Zeng, Liang Su, Lu Luo, Chunxia Dong, Zhiwan Zheng