Background Dermatophytoses in children are common pathologies worldwide caused mainly by Trichophyton rubrum. However, due to the globalization and the atypical pets that people nowadays own, some zoonotic species are also involved in these lesions. Case report We present two cases of tinea faciei caused by the zoonotic mould Trichophyton erinacei in two children that owned a guinea pig and a hedgehog

Critically ill COVID-19 patients have higher pro-inflammatory (IL-1, IL-2, IL-6, tumor necrosis alpha) and anti-inflammatory (IL-4, IL-10) cytokine levels, less CD4 interferon-gamma expression, and fewer CD4 and CD8 cells. This severe clinical situation increases the risk of serious fungal infections, such as invasive pulmonary aspergillosis, invasive candidiasis or Pneumocystis jirovecii pneumonia

Antecedentes Candida albicans y Rhodotorula mucilaginosa son levaduras de importancia clínica en la cavidad oral. En pacientes inmunocomprometidos estas levaduras pueden producir enfermedades que deben ser controladas con antimicrobianos. Objetivos Evaluar y comparar la eficacia antifúngica de seis enjuagues bucales comerciales frente a aislamientos de C. albicans y R. mucilaginosa. Métodos Fue evaluada

Antecedentes La diabetes mellitus es un problema de salud pública en México. La tendencia de la enfermedad es creciente y del año 2000 al 2017 se confirmaron 7,32 millones de casos nuevos. Las micosis pulmonares son una de las posibles complicaciones de mayor gravedad. Objetivos Describir la frecuencia y las características clínicas de pacientes con diagnóstico de micosis pulmonar e identificar los

Antecedentes El género Curvularia incluye hongos filamentosos dematiáceos cada vez más reconocidos como patógenos en pacientes inmunocomprometidos. Las entidades clínicas más comunes con las que se asocia este hongo son la sinusitis alérgica, la infección cutánea y la queratitis. En este trabajo se describe el primer caso descrito en España de infección cutánea por Curvularia pallescens y su tratamiento

Background Rhodotorula species were traditionally considered non-virulent environmental microorganisms, but are nowadays considered important human pathogens, especially in immunocompromised individuals. Case report We present the case of a 73 year-old man with diarrhea, anorexia and fever. In the blood analyses, both aerobic blood culture bottles yielded the growth of Rhodotorula dairenensis. The

Background Cutaneous congenital candidiasis (CCC) is a rare condition consisting of invasive fungal infection of the epidermis and dermis that mostly affects preterm infants. Maternal vaginal candidiasis is present in half of the cases, although the occurrence of invasive candidiasis during pregnancy or peripartum period is exceptional. Case report We present the case of a full-term infant that was

BACKGROUND Schizophyllum commune is a basidiomycete fungus which is widely distributed in nature. Its role as responsible for disease in humans is not well known, partly due to its difficult identification. The incorporation of mass spectrometry techniques (MALDI-TOF) and molecular biology to the laboratories has allowed the description of a greater number of cases. CASE REPORT In this paper, we present

Antecedentes La primoinfección por Pneumocystis jirovecii ocurre de forma asintomática antes de los 6 meses de edad, lo que sugiere que la infección se adquiere muy precozmente en la vida. Se ha descrito también la presencia de neumonía por Pneumocystis en recién nacidos, lo que indica la necesidad de estudiar la colonización en el binomio madre-hijo. Objetivos Evaluar la prevalencia de colonización

Cystic fibrosis (CF) is one of the most frequent recessive inherited diseases in western countries. Advances in medical care have led to a substantial increase in the life expectancy of CF patients. Survival beyond adolescence has permitted to see fungi not only as late colonizers, but also as potential pathogens responsible of allergic reactions and chronic infections related to lung function deterioration

Antecedentes La histoplasmosis es una micosis sistémica endémica en América con pocos casos reportados en pediatría. Objetivos Describir la epidemiología, formas clínicas y evolución de la histoplasmosis en niños de un hospital pediátrico en Argentina. Métodos El estudio, retrospectivo y descriptivo, se llevó a cabo entre enero de 2008 y diciembre de 2016 en el Hospital de Pediatría «Prof. Dr. Juan

Antecedentes La histoplasmosis diseminada (HD) es una infección fúngica oportunista en pacientes con infección por VIH gravemente inmunocomprometidos. El síndrome hemofagocítico (SHF), que puede presentarse en estos pacientes coinfectados cuando la respuesta inmunitaria está significativamente alterada, suele estar asociado a una elevada mortalidad. Objetivos Describir las características epidemiológicas

Tumor necrosis factor (TNF) is a proinflammatory cytokine involved in a wide range of important physiologic processes and has a pathologic role in some diseases. TNF antagonists (infliximab, adalimumab, etanercept) are effective in treating inflammatory conditions. Antilymphocyte biological agents (rituximab, alemtuzumab), integrin antagonists (natalizumab, etrolizumab and vedolizumab), interleukin

Background Candidemia is a life-threatening fungal infection characterized by the presence of Candida in the blood. Aims To describe the clinical–epidemiological features and main risk factors among patients with candidemia admitted to Intensive Care Unit. Methods A cross-sectional, retrospective and observational study was performed between January 2015 and July 2016. Laboratory reports and medical

Background Candida albicans is the main agent that causes vulvovaginal candidiasis. Resistance among isolates to azole antifungal agents has been reported. Aims Due to the well-known antifungal potential of curcumin, the purpose of this work was to evaluate the in vitro anticandidal activity of curcumin and its effect in the treatment of experimental vulvovaginal candidiasis. Methods The anticandidal

Background In a previous work we showed the feasibility of an interferon gamma release assay (IGRA) for detecting latent infection by Histoplasma capsulatum. While in that proof-of-concept study we used crude fungal extracts as antigens, the newest IGRAs developed for other infections are based on molecularly defined antigens, mostly on mixtures of immunogenic peptides. Aims To identify proteins in

Background Candida yeasts are considered the main agents of nosocomial fungal infections. Aims This study aimed to establish the epidemiological profile of patients with candiduria hospitalized in the capital of the State of Mato Grosso, in the Central-Western region of Brazil. Methods Patients from three private hospitals and a public hospital participated in the study. This was an observational and

Candida auris es una nueva especie de Candida responsable de diversos brotes nosocomiales en varios países del mundo, incluida España; es resistente al fluconazol y se han descrito cepas multi y panresistentes. Presenta una elevada transmisibilidad y extensa supervivencia en el entorno hospitalario, lo que es causa de brotes de larga duración difíciles de detectar en fases tempranas y dificulta su

Background The prevalence of opportunistic yeast infections has increased in recent decades as the result of an increasing immunocompromised patient population. Aims To evaluate ribosomal RNA (rRNA) gene sequence to identify medically important yeast species, to investigate the performance of both the rRNA gene internal transcribed spacer (ITS) and D1/D2 region in identifying clinically relevant yeasts