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Amyotrophic Lateral Sclerosis and Pain: A Narrative Review from Pain Assessment to Therapy Behav. Neurol. (IF 2.8) Pub Date : 2024-3-16 Vincenzo Pota, Pasquale Sansone, Sara De Sarno, Caterina Aurilio, Francesco Coppolino, Manlio Barbarisi, Francesco Barbato, Marco Fiore, Gianluigi Cosenza, Maria Beatrice Passavanti, Maria Caterina Pace
Amyotrophic lateral sclerosis (ALS) is the most frequent neurodegenerative disease of the motor system that affects upper and lower motor neurons, leading to progressive muscle weakness, spasticity, atrophy, and respiratory failure, with a life expectancy of 2–5 years after symptom onset. In addition to motor symptoms, patients with ALS have a multitude of nonmotor symptoms; in fact, it is currently
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Daily Functionality of People with Low Vision: The Impact of Visual Acuity, Depression, and Life Orientation—A Cross-Sectional Study Behav. Neurol. (IF 2.8) Pub Date : 2024-2-26 Mara Gkioka, Stavroula Almpanidou, Niki Lioti, Diamantis Almaliotis, Vasileios Karampatakis
Background. Low vision (LV) has a significant negative impact on the activities of daily life as well as on the psychological health of patients. Objectives. The objective of this study is to investigate psychological, clinical, and demographic factors that may impact the daily functionality of patients with LV. Methods. A convenience sample of 53 patients, meeting the WHO criteria for LV, was recruited
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Exploring the Experience of Living with Pain after Spinal Cord Injury: A Qualitative Study Behav. Neurol. (IF 2.8) Pub Date : 2024-2-2 Mokgadi Kholofelo Mashola, Elzette Korkie, Diphale Joyce Mothabeng
A spinal cord injury is a life-changing experience that results in functional limitations and an increased risk of secondary health conditions. People with spinal cord injury identify pain as the most devastating health problem following their injury that not only affects their social life but their mental well-being as well. This study is aimed at exploring the lived experience of living with pain
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Abnormal Amygdala Subregion Functional Connectivity in Patients with Crohn’s Disease with or without Anxiety and Depression Behav. Neurol. (IF 2.8) Pub Date : 2024-1-30 Jingwen Sun, Wei Sun, Kecen Yue, Yin Zhang, Xintong Wu, Wenjia Liu, Ling Zou, Haifeng Shi
Objective. The aim of this study was to explore the resting-state functional connectivity (rsFC) of amygdala subregions in healthy controls (HCs) and in patients with Crohn’s disease (CD) both with and without anxiety or depression. Materials and Methods. A total of 33 patients with CD and with anxiety or depression (CDad group), 31 patients with CD but without anxiety or depression (CDnad group),
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Elucidating the Visual Snow Spectrum: A Latent Class Analysis Study Behav. Neurol. (IF 2.8) Pub Date : 2024-1-19 Amy Claire Thompson, Patrick T. Goodbourn, Jason D. Forte
Objective. People with visual snow syndrome (VSS) experience a range of perceptual phenomena, in addition to visual snow (VS; flickering pinpricks of light throughout the visual field). We investigated the patterns of perceptual phenomena associated with VSS in a large sample of people without prior knowledge of VSS or its associated symptoms. Methods and Measures. Two thousand participants completed
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Mice Recognise Mice in Neighbouring Rearing Cages and Change Their Social Behaviour Behav. Neurol. (IF 2.8) Pub Date : 2024-1-16 Hiroshi Ueno, Yu Takahashi, Sachiko Mori, Shinji Murakami, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara
Mice are social animals that change their behaviour primarily in response to visual, olfactory, and auditory information from conspecifics. Rearing conditions such as cage size and colour are important factors influencing mouse behaviour. In recent years, transparent plastic cages have become standard breeding cages. The advantage of using a transparent cage is that the experimenter can observe the
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Knowledge Structure and Emerging Trends of Mild Cognitive Impairment with Dyssomnias in Recent 20 Years: A Bibliometric Analysis via CiteSpace and VOSviewer Behav. Neurol. (IF 2.8) Pub Date : 2024-1-6 Haoyu Huang, Zesen Zhuang, Yiwen Wan, Jiao Shi, Xu Yuan, Dan Wang, Shangjie Chen
Background. Mild cognitive impairment (MCI), an intermediate stage between normal aging and dementia, has emerged as a prominent research area in geriatric care due to its heightened propensity for progressing toward dementia. Sleep plays a pivotal role in cognitive function, with dyssomnias not only exacerbating cognitive and affective symptoms associated with neurodegenerative diseases but also contributing
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Presence and Characteristics of Behavioral and Psychological Symptoms in Subacute Stroke Patients with Cognitive Impairment Behav. Neurol. (IF 2.8) Pub Date : 2023-12-28 Daisuke Ito, Naoki Mori, Ayaka Shimizu, Ayako Narita, Sachiko Sakata, Kaoru Honaga, Kunitsugu Kondo, Yohei Otaka
This retrospective cross-sectional study is aimed at investigating the prevalence and characteristics of behavioral and psychological symptoms (BPS) in subacute stroke patients with cognitive impairment. The Neuropsychiatric Inventory-Questionnaire (NPI-Q) was used to assess BPS. A total of 358 consecutive patients with first-ever stroke admitted to rehabilitation wards and with Mini-Mental State Examination
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The Application Effect of Craniotomy through Transsylvian Rolandic Point-Insular Approach on Hypertensive Intracerebral Hemorrhage in Posterior Basal Ganglia Behav. Neurol. (IF 2.8) Pub Date : 2023-11-29 Guobing Wang, Xin Chen, Linghu Meng, Ying Liu, Yongjian Dai, Wenxin Wang
Objective. To evaluate the hematoma clearance and safety of small bone window craniotomy through the lateral fissure Rolandic point-insular lobe approach for patients with hypertensive intracerebral hemorrhage (HICH) in posterior basal ganglia. Methods. This retrospective study enrolled a total of 86 patients with HICH in the posterior basal ganglia region who underwent surgery between January 2020
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Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients Behav. Neurol. (IF 2.8) Pub Date : 2023-11-24 Jiangjie Sun, Jingyi Fang, Chenchen Zhang, Nannan Jia, Weiming Zhao, Jinjian Gao, Yingying Huang, Jiqing Hao, Liping Zhang
Aim. To understand the degree of oncology patients’ awareness of drug clinical trials and oncology patients’ willingness to participate in drug clinical trials and the factors influencing them. Methods. The differences in the relevant variables of patients’ willingness to accept clinical trials were analyzed, and a descriptive analysis was done for the measurement data (mean and standard deviation)
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Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases Behav. Neurol. (IF 2.8) Pub Date : 2023-11-23 Ya-Min Ma, Lan Zhao
MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in animals and plants. They can inhibit translation or overexpression by combining with mRNA and participate in posttranscriptional regulation of genes, resulting in reduced expression of target proteins, affecting the development, growth, aging, metabolism, and other physiological and pathological processes of animals
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Oral Administration of Lactobacillus Inhibits the Permeability of Blood-Brain and Gut Barriers in a Parkinsonism Model Behav. Neurol. (IF 2.8) Pub Date : 2023-11-9 Angélica Y. Nápoles-Medina, Blanca R. Aguilar-Uscanga, Josué R. Solís-Pacheco, Aldo R. Tejeda-Martínez, Luis J. Ramírez-Jirano, María F. Urmeneta-Ortiz, Veronica Chaparro-Huerta, Mario E. Flores-Soto
It has recently been shown that the administration of probiotics can modulate the microbiota-gut-brain axis and may have favorable effects in models of Parkinson’s disease. In this study, we used a hemiparkinsonism model induced by the neurotoxin 6-OHDA to evaluate the efficacy of the administration of a four-week administration of a mixture containing the microorganisms Lactobacillus fermentum LH01
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Development and Validation of the Amharic Version of Self-Efficacy and Outcome Expectancy Measures on Intention to Take Preventive Actions on Noncommunicable Disease Behav. Neurol. (IF 2.8) Pub Date : 2023-10-31 Shumye Molla Legesse, Habtamu Wondimu
This study is aimed at developing and accessing the validity and reliability of an Amharic version of the self-efficacy and outcome expectancy measures on noncommunicable disease prevention strategies. The intentions to take protective measures on NCDs’ self-efficacy and outcome expectancy scales were created in Amharic using a sequential nine-step process that included translation and contextualization
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Emerging Therapeutic Potential of Cannabidiol (CBD) in Neurological Disorders: A Comprehensive Review Behav. Neurol. (IF 2.8) Pub Date : 2023-10-12 Kuldeep Singh, Bharat Bhushan, Dilip Kumar Chanchal, Satish Kumar Sharma, Ketki Rani, Manoj Kumar Yadav, Prateek Porwal, Shivendra Kumar, Ashwani Sharma, Tarun Virmani, Girish Kumar, Abdullah Al Noman
Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its potential therapeutic applications. This thorough analysis explores the increasing significance of CBD in treating neurological conditions including epilepsy, multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease, which present major healthcare concerns on a worldwide scale. Despite the lack of available
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Psychometric Properties of the Posttraumatic Stress Disorder Checklist among the Lebanese Population Exposed to the Beirut Explosion: A Cross-Sectional Study during the COVID-19 Pandemic Behav. Neurol. (IF 2.8) Pub Date : 2023-10-3 Fadwa Alhalaiqa, Othman A. Alfuqaha, Rami Masa’Deh, Anas H. Khalifeh, Mahmoud Alsaraireh, Natija S. Manaa, Osama Alkouri, Omar Al Omari
Objective. This study was aimed at testing the psychometric properties of the posttraumatic stress disorder (PTSD) checklist for the Diagnostic Statistical Manual version 5 (DSM-5) (PCL-5) among the Lebanese population and at identifying the prevalence of PTSD. Design. A cross-sectional survey of PCL-5 among 950 Lebanese, using the online survey platform by Google Form, was conducted. Snowball recruitment
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Smaller and Denser Speech Graphs in Nondemented Patients with Progressive Supranuclear Palsy Behav. Neurol. (IF 2.8) Pub Date : 2023-9-25 Jinghong Ma, Guanyu Zhang, Xiaomin Sun, Piu Chan, Zheng Ye
The well-established semantic fluency test measures the ability to produce a sequence of spoken words from a particular category within a limited period of time. Like patients with Parkinson’s disease (PD), patients with progressive supranuclear palsy (PSP) tend to produce fewer correct words than age-matched healthy adults. This study further examined the difference between patients with PSP and PD
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A Systematic Review of MRI Studies and the “Emotional paiN and social Disconnect (END)” Brain Model of Suicidal Behavior in Youth Behav. Neurol. (IF 2.8) Pub Date : 2023-9-23 Olga Tymofiyeva, Katherine W. Reeves, Chace Shaw, Eric Lopez, Sepehr Aziz, Jeffrey E. Max, Tony T. Yang
Introduction. Risk of suicidal ideation and suicidal behaviors greatly increases during adolescence, and rates have risen dramatically over the past two decades. However, few risk factors or biomarkers predictive of suicidal ideation or attempted suicide have been identified in adolescents. Neuroimaging correlates hold potential for early identification of adolescents at increased risk of suicidality
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Effect on Satisfactory Seizure Control and Heart Rate Variability of Thread-Embedding Acupuncture for Drug-Resistant Epilepsy: A Patient-Assessor Blinded, Randomized Controlled Trial Behav. Neurol. (IF 2.8) Pub Date : 2023-9-19 Van-Dan Nguyen, Duc-Thang Pham, Minh-An Thuy Le, Guo-Ming Shen
This randomized controlled trial investigates the efficacy of thread-embedding acupuncture (TEA) compared to sham TEA in treating drug-resistant epilepsy (DRE). Fifty-four DRE outpatients were randomly divided into two groups: TEA (27 patients) and sham TEA (27 patients). Both groups received four sessions of TEA or sham TEA, spaced four weeks apart, targeting GV20, GV14, BL15, BL18, ST40, and GB34
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Behavior Management Training for Parents of Children with Preschool ADHD Based on Parent-Child Interactions: A Multicenter Randomized Controlled, Follow-Up Study Behav. Neurol. (IF 2.8) Pub Date : 2023-9-11 Min Feng, Juncai Xu, Mengyao Zhai, Qiaorong Wu, Kangkang Chu, Liping Xie, Rong Luo, Huiping Li, Qiong Xu, Xiu Xu, Xiaoyan Ke
Objective. There is a need to develop optimized, evidence-based parent training programs tailored for preschoolers with attention deficit hyperactivity disorder (ADHD). The objective of this study was to explore a behavioral management training program aimed at the parents of preschool children with ADHD, which directly analyzes parent-child interaction from the perspective of system theory, and the
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Retracted: Customer Experience towards the Product during a Coronavirus Outbreak. Behav. Neurol. (IF 2.8) Pub Date : 2023-08-09 Behavioural Neurology
[This retracts the article DOI: 10.1155/2022/4279346.].
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Retracted: The Impact of Online Learning System on Students Affected with Stroke Disease. Behav. Neurol. (IF 2.8) Pub Date : 2023-08-09 Behavioural Neurology
[This retracts the article DOI: 10.1155/2022/4847066.].
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Retracted: Ensemble Classification Approach for Sarcasm Detection. Behav. Neurol. (IF 2.8) Pub Date : 2023-08-09 Behavioural Neurology
[This retracts the article DOI: 10.1155/2021/9731519.].
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Modeling Suicidality with Multimodal Impulsivity Characterization in Participants with Mental Health Disorder Behav. Neurol. (IF 2.8) Pub Date : 2023-8-5 Nidal Moukaddam, Bishal Lamichhane, Ramiro Salas, Wayne Goodman, Ashutosh Sabharwal
Introduction. Suicide is one of the leading causes of death across different age groups. The persistence of suicidal ideation and the progression of suicidal ideations to action could be related to impulsivity, the tendency to act on urges with low temporal latency, and little forethought. Quantifying impulsivity could thus help suicidality estimation and risk assessments in ideation-to-action suicidality
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Management Practice and Clinical Outcomes of Dementia in Sub-Saharan Africa: A Systematic Review Behav. Neurol. (IF 2.8) Pub Date : 2023-7-25 Dessale Abate Beyene, Alemseged Beyene Berha
Background. Dementia is a severe neurodegenerative disorder and it is a group of acquired symptoms associated with impaired cognitive functions. In low-income settings particularly in Sub-Saharan Africa (SSA), it is often seen as part of normal aging. Environmental, behavioral, and lifestyle interventions have the potential to alter the disease course of dementia. Objective. This study is aimed to
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Magnitude and Determinant Factors of Pediatrics Seizures in Pediatrics Emergency Unit at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 2020: A Retrospective and Descriptive Study Behav. Neurol. (IF 2.8) Pub Date : 2023-7-14 Asaminew Habtamu, Rahel Argaw, Wagari Tuli, Ayalew Moges
Background. One of the most prevalent medical problems affecting kids is epilepsy, which is the most prevalent chronic neurological condition in kids in both developed and developing nations. The spectrum of diseases that make up childhood epilepsy syndromes ranges from mild to potentially fatal. Children may experience seizures due to a variety of illnesses, such as infection, severe brain injury
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Edaravone Improves Streptozotocin-Induced Memory Impairment via Alleviation of Behavioral Dysfunction, Oxidative Stress, Inflammation, and Histopathological Parameters Behav. Neurol. (IF 2.8) Pub Date : 2023-7-12 Mahdieh Anoush, Soroush Bijani, Fatemeh Moslemifar, Fatemeh Jahanpour, Ali Kalantari-Hesari, Mir-Jamal Hosseini
Alzheimer’s disease (AD), as the main cause of dementia, has a progressive and neurodegenerative pattern with number of cases increasing over the next decades. Therefore, discovering an effective treatment with the ability to invert memory impairment and pathophysiological events of AD seems to be required. The present study performed to investigate the probable effects of Edaravone (EDV) in AD-like
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Construction of a Diagnostic Model and a lncRNA-Associated ceRNA Network Based on Apoptosis-Related Genes for Schizophrenia Behav. Neurol. (IF 2.8) Pub Date : 2023-6-20 Zi-long Ma, Run-lan Wang, Lili Meng
Background and Aim. Schizophrenia is a complex psychiatric disorder with an unknown etiology. Previous studies suggest that apoptosis is potentially involved in the pathophysiology of schizophrenia, but whether apoptotic markers can help diagnosis of schizophrenia has not been reported. This study aimed to establish a potential diagnostic model based on apoptosis-related gene expression in blood samples
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Epigallocatechin Gallate Ameliorates Nicotine Withdrawal Conditions-Induced Somatic and Affective Behavior Changes in Mice and Its Molecular Mechanism Behav. Neurol. (IF 2.8) Pub Date : 2023-6-13 Mahardian Rahmadi, Ahmad D. Nurhan, Retno I. A. Rahmawati, Theresia F. Damayanti, Djoko A. Purwanto, Junaidi Khotib
In nicotine withdrawal (NW) conditions, molecular changes, such as increasing corticotropin-releasing factor (CRF) in the amygdala, and melanocortin signaling in the hypothalamus, can occur in the brain, leading to increased feeding behavior and body weight as somatic changes as well as high anxiety-like behavior as an affective changes. Therefore, this research aimed to investigate the effect of epigallocatechin
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Vitamin B6 Deficiency Induces Autism-Like Behaviors in Rats by Regulating mTOR-Mediated Autophagy in the Hippocampus Behav. Neurol. (IF 2.8) Pub Date : 2023-5-9 Lijuan Chen, Jing Li, Xinglian Liu, Zhiwei Zhao, Yan Jin, Yikun Fu, Aiqin Zhou, Chengqun Wang, Yan Zhou
Vitamin B6 (VB6) exhibits therapeutic effects towards autism spectrum disorder (ASD), but its specific mechanism is poorly understood. Rat dams were treated with VB6 standard, VB6 deficiency, or VB6 supplementary diet, and the same treatment was provided to their offspring, with their body weights monitored. Three-chambered social test and open field test were employed to evaluate the effect of VB6
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Possible Effects of Acupuncture in Poststroke Aphasia Behav. Neurol. (IF 2.8) Pub Date : 2023-4-12 Bifang Zhuo, Shizhe Deng, Boxuan Li, Weiming Zhu, Menglong Zhang, Chenyang Qin, Zhihong Meng
Neural plasticity promotes the reorganization of language networks and is an essential recovery mechanism for poststroke aphasia (PSA). Neuroplasticity may be a pivotal bridge to elucidate the potential recovery mechanisms of acupuncture for aphasia. Therefore, understanding the neuroplasticity mechanism of acupuncture in PSA is crucial. However, the underlying therapeutic mechanism of neuroplasticity
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Association between Ambient Illumination and Cognitive Impairment: A Population-Based Study of Older Behav. Neurol. (IF 2.8) Pub Date : 2023-4-10 Tieyi Shi, Baozhong Chen
It is well-established that light therapy can alleviate cognitive impairment, and ambient illumination (AI) can quantify the amount of exposure to light. However, the relationship between AI and cognitive impairment has been largely understudied. Objectives. We aimed to examine the cross-sectional associations between AI and impaired cognition using data from the National Health and Nutrition Examination
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Cucurbita maxima Seeds Reduce Anxiety and Depression and Improve Memory Behav. Neurol. (IF 2.8) Pub Date : 2023-3-22 Shahana Wahid, Ali Alqahtani, Rafeeq Alam Khan
The current study was planned to assess the neuropharmacological benefits of the Cucurbita maxima seed. These seeds have been conventionally used for the nutritional as well as amelioration of various diseases. However, there was a need to provide a pharmacological basis for such use. Four central nervous system-related functions, that is, anxiety, depression, memory, and motor coordination, were evaluated
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Acupuncture in the Treatment of Abnormal Muscle Tone in Children with Cerebral Palsy: A Meta-Analysis Behav. Neurol. (IF 2.8) Pub Date : 2023-3-21 Yan Yuanjie, Xue Jianyi, Xu Jinyan, Huang Mao, Yan Siyang, Yin Zhenjin
Objective. To analyse the clinical efficacy of acupuncture and routine treatment in improving dystonia in children with cerebral palsy. Method. The randomized controlled trials published from the establishment of the databases to August 2022 on acupuncture in the treatment of dystonia in children with cerebral palsy were collected and comprehensively searched in China national knowledge infrastructure
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Attenuation of Strychnine-Induced Epilepsy Employing Amaranthus viridis L. Leaves Extract in Experimental Rats Behav. Neurol. (IF 2.8) Pub Date : 2023-3-14 Aashish Bharadwaj, Ashwani Sharma, Talever Singh, Devender Pathak, Tarun Virmani, Girish Kumar, Anjali Sharma, Abdulsalam Alhalmi
Objective. Epilepsy is one of the most prevalent neurological illnesses defined by periodic seizures with or without loss of consciousness caused by aberrant neural activity. There are many allopathic medications available for the treatment of epilepsy such as phenytoin (PHY), but the side effects are a major concern. Therefore, the present study involved the evaluation of the pharmacological significance
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Naringin Protects against Tau Hyperphosphorylation in Aβ25–35-Injured PC12 Cells through Modulation of ER, PI3K/AKT, and GSK-3β Signaling Pathways Behav. Neurol. (IF 2.8) Pub Date : 2023-2-15 Qi Qiu, Xia Lei, Yueying Wang, Hui Xiong, Yanming Xu, Huifeng Sun, Hongdan Xu, Ning Zhang
Alzheimer’s disease (AD) is the most common form of dementia and a significant social and economic burden. Estrogens can exert neuroprotective effects and may contribute to the prevention, attenuation, or even delay in the onset of AD; however, long-term estrogen therapy is associated with harmful side effects. Thus, estrogen alternatives are of interest for countering AD. Naringin, a phytoestrogen
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Systematic Review and Meta-Analysis of Clinically Relevant Executive Functions Tests Performance after COVID-19 Behav. Neurol. (IF 2.8) Pub Date : 2023-2-9 Boris B. Velichkovsky, Anna Y. Razvaliaeva, Alena A. Khlebnikova, Piruza A. Manukyan, Vladimir N. Kasatkin, Artem V. Barmin
It is widely known that COVID-19 has a number of prolonged effects on general health, wellbeing, and cognitive functioning. However, studies using differentiated performance measures of cognitive functions are still not widely spread making it hard to assess the exact functions that get impaired. Taking into account the similarities between post-COVID ‘brain fog’ and chemofog, we hypothesized that
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Cognitive Functioning in Adults with Phenylketonuria in a Cohort of Spanish Patients Behav. Neurol. (IF 2.8) Pub Date : 2023-2-8 P. M. Luna, J. F. López-Paz, M. García, I. Amayra, O. Martínez, M. Pérez, A. A. Rodríguez, P. Pérez-Núñez, I. Ceberio, N. Mansilla, C. Soria
The early introduction of a low phenylalanine (Phe) diet has been demonstrated to be the most successful treatment in subjects with phenylketonuria (PKU), especially for preventing severe cognitive and neurological damages. However, it still concerns that even if treated in the first months of life with supplements and following a diet, they can show slight scores below people without PKU in neuropsychological
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Long Non-coding RNA KTN1-AS1 Targets miR-505 to Promote Glioblastoma Progression Behav. Neurol. (IF 2.8) Pub Date : 2023-1-31 Kai Guo, Lingling Fang, Mingjian Li, Aizheng Li, Na Liu
Glioblastoma (GBM) is a highly malignant cancer, the prognosis of which is pretty poor. Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs, which play important roles in carcinogenesis process of many cancers including GBM. In this study, we want to clarify the expression, biological function, and molecular mechanism of lncRNA KTN1 antisense RNA 1 (KTN1-AS1) in GBM tumor progression. We
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Motor Resonance Flexibility to Emotion-Enriched Context in Parkinson’s Disease Patients Behav. Neurol. (IF 2.8) Pub Date : 2022-12-30 Giovanna Lagravinese, Ambra Bisio, Marco Bove, Alessandro Botta, Gaia Bonassi, Roberta Marchese, Piero Ruggeri, Elisa Pelosin, Laura Avanzino
In healthy people, motor resonance mechanisms are flexible to negative emotional contextual clues with greater motor resonance during the observation of a reach to grasp movement performed in an environment eliciting disgust. The link between emotion and motor control has become an interesting topic in Parkinson’s disease (PD). Here, we aimed to study the response of the mirror neuron system, specifically
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Chronic Inhibition of Aggressive Behavior Induces Behavioral Change in Mice Behav. Neurol. (IF 2.8) Pub Date : 2022-12-29 Hiroshi Ueno, Yu Takahashi, Shinji Murakami, Kenta Wani, Tetsuji Miyazaki, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara
Suppression of anger is more common than its expression among Asian individuals. Emotional suppression is considered an unhealthy emotional regulation. Most studies on emotional suppression have concluded that suppression adversely affects social outcomes, with approximately 5% of the world’s population suffering from emotional disorders. However, anger suppression has not received academic attention
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RDW-to-ALB Ratio Is an Independent Predictor for 30-Day All-Cause Mortality in Patients with Acute Ischemic Stroke: A Retrospective Analysis from the MIMIC-IV Database Behav. Neurol. (IF 2.8) Pub Date : 2022-12-15 Ping Liu, Su Luo, Xiang-jie Duan, Xiang Chen, Quan Zhou, Yan Jiang, Xia Liu
Purpose. Previous studies have shown that the peripheral red blood cell distribution width (RDW) and human serum albumin (ALB) were both predictors of the risk and mortality of cerebrovascular diseases, and the ratio of RDW to ALB (RAR) was a combined new index that can predict the prognosis of the cardiovascular and respiration systemic diseases, but its role in cerebrovascular diseases had not been
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Central Auditory Processing Disorder in Patients with Amnestic Mild Cognitive Impairment Behav. Neurol. (IF 2.8) Pub Date : 2022-12-15 Ga-Young Kim, HyangHee Kim, Hee Jin Kim, Sang Won Seo, Duk L. Na, Chung Mo Nam, Byoung Seok Ye, Il Joon Moon
Background. This study was conducted to comprehensively examine the central auditory processing (CAP) abilities of patients with amnestic mild cognitive impairment (aMCI) as well as to compare the results with cognitively normal elderly controls. Methods. A total of 78 participants were screened through pure-tone audiometry and word recognition score in order to exclude peripheral auditory dysfunction
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Dark Chocolate Intake May Reduce Fatigue and Mediate Cognitive Function and Gray Matter Volume in Healthy Middle-Aged Adults Behav. Neurol. (IF 2.8) Pub Date : 2022-12-13 Kiyotaka Nemoto, Keisuke Kokubun, Yousuke Ogata, Yasuharu Koike, Tetsuaki Arai, Yoshinori Yamakawa
Background. Dark chocolate has attracted attention for its potential for cognitive improvement. Though some reports indicate that dark chocolate is good for cognitive function, others raise doubts. This inconsistency in past results reflecting the relationship between dark chocolate and cognitive function indicates the potential existence of factors that mediate between dark chocolate intake and cognitive
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Verbal Reasoning Impairment in Parkinson’s Disease Behav. Neurol. (IF 2.8) Pub Date : 2022-12-10 Antonina Luca, Giulia Donzuso, Concetta D’Agate, Claudio Terravecchia, Calogero Cicero Edoardo, Giovanni Mostile, Giorgia Sciacca, Alessandra Nicoletti, Mario Zappia
Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets. Results. Eighty-seven PD patients (51 men; mean age years)
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Multimodal Assessment of Changes in Physiological Indicators when Presenting a Video Fragment on Screen (2D) versus a VR (3D) Environment Behav. Neurol. (IF 2.8) Pub Date : 2022-11-28 Elena Kriklenko, Anastasia Kovaleva, Aleksei Klimenko, Usman Dukuev, Sergey Pertsov
The increasing role of virtual environments in society, especially in the context of the pandemic and evolving metaverse technologies, requires a closer study of the physiological state of humans using virtual reality (VR) for entertainment, work, or learning. Despite the fact that many physiological reactions to the content presented in various modalities under VR conditions have already been described
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The Orthographic Ambiguity of the Arabic Graphic System: Evidence from a Case of Central Agraphia Affecting the Two Routes of Spelling Behav. Neurol. (IF 2.8) Pub Date : 2022-11-16 Assia Boumaraf, Sonia Bekal, Joël Macoir
The Arabic writing system includes ambiguities that create difficulties in spelling. These ambiguities relate mainly to the long vowels, some phoneme-grapheme conversions, lexical particularities, and the connectivity of letters. In this article, the first to specifically explore acquired spelling impairments in an Arabic-speaking individual, we report the case of CHS, who presented with agraphia following
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Postpandemic Stress Disorder among Health Care Personnel: A Cross-Sectional Study (Silesia, Poland) Behav. Neurol. (IF 2.8) Pub Date : 2022-11-14 Mateusz Grajek, Patryk Szlacheta, Karolina Sobczyk, Karolina Krupa-Kotara, Beata Łabuz-Roszak, Ilona Korzonek-Szlacheta
Background. Postpandemic stress disorder (PPSD) is an unofficial term that refers to posttraumatic stress disorder (PTSD), a mental disorder resulting from increased stress, anxiety, and trauma associated with unpleasant life experiences. Many scientific studies indicate that symptoms of increased stress, job burnout, anxiety, and depressive disorders are associated with medical personnel performing
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Clinical Features and Risk Factors of Mortality in Patients with Posterior Reversible Encephalopathy Syndrome Behav. Neurol. (IF 2.8) Pub Date : 2022-11-14 Hong-Wei Cui, Ru-Yi Lei, Bo-Ai Zhang
Objective. Although the prognosis of posterior reversible encephalopathy syndrome (PRES) is usually favourable and most patients wholly recover, the disorder can result in death in some patients. To date, the data on clinical features and risk factors for death are still lacking; therefore, we aim to investigate the clinical features and long-term prognostic risk factors of PRES in the present study
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Association between Twenty-Four-Hour Ambulatory Blood Pressure Variability and Cerebral Small Vessel Disease Burden in Acute Ischemic Stroke Behav. Neurol. (IF 2.8) Pub Date : 2022-10-18 Jun Shen, Lu Yang, Ziwei Xu, Wenshi Wei
Objective. This study is aimed at investigating the association between the twenty-four-hour ambulatory blood pressure variability monitoring (ABPM) and cerebral small vessel disease (cSVD) burden in acute ischemic stroke (AIS) patients. Methods. 115 AIS patients with demographics, vascular risk factors, 24 h ABPM, and brain magnetic resonance imaging (MRI) were retrospectively enrolled. 3.0 T MRI
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Clinical Features in Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency: A Systematic Review Behav. Neurol. (IF 2.8) Pub Date : 2022-10-11 Susanna Rizzi, Carlotta Spagnoli, Daniele Frattini, Francesco Pisani, Carlo Fusco
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare congenital autosomal recessive metabolic disorder caused by pathogenic homozygous or compound heterozygous variants in the dopa decarboxylase (DDC) gene. Adeno-associated viral vector-mediated gene transfer of the human AADC gene into the putamina has become available. This systematic review on PubMed, Scopus databases, and other sources
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On the Relationship between Speech Intelligibility and Fluency Indicators among English-Speaking Individuals with Parkinson’s Diseases Behav. Neurol. (IF 2.8) Pub Date : 2022-10-3 Chin-Ting Liu, Shiao-Wei Chu, Yuan-Shan Chen
The purpose of the study is to investigate how much of variance in Parkinson’s Disease (PD) individuals’ speech intelligibility could be predicted by seven speech fluency indicators (i.e., repetition, omission, distortion, correction, unfilled pauses, filled pauses, and speaking rate). Speech data were retrieved from a database containing a reading task produced by a group of 16 English-speaking individuals
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Relationship between Self-Efficacy and Headache Impact, Anxiety, and Physical Activity Levels in Patients with Chronic Tension-Type Headache: An Observational Study Behav. Neurol. (IF 2.8) Pub Date : 2022-09-06 Ángel González de la Flor, Guillermo García Pérez de Sevilla, Diego Domíngez Balmaseda, Daniel Martín Vera, María Montero Martínez, Jose Ángel Del Blanco Muñiz
Background. Chronic tension-type headache is the primary headache with the highest prevalence. The present study is aimed at analyzing the associations between patient self-efficacy and headache impact with pain characteristics, kinesiophobia, anxiety sensitivity, and physical activity levels in subjects with chronic tension-type headache. Materials and Methods. An observational descriptive study was
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Revealing the Role of Social Support on Cognitive Deficits in Fibromyalgia Syndrome Behav. Neurol. (IF 2.8) Pub Date : 2022-09-01 Carmen M. Galvez-Sánchez, Gustavo A. Reyes del Paso, Casandra I. Montoro
Despite the relevance of cognitive deficits in fibromyalgia syndrome (FMS) and the attempts to elucidate the influence of the disorder symptoms in the cognitive decline reported by patients, no studies have explored the specific role of social support on cognition in FMS. Social support has been shown to be an essential modulator factor on cognitive performance in other diseases. Sixty-four women with
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Establishment and Validation of a Predictive Model for Radiation-Associated Aspiration Pneumonia in Patients with Radiation-Induced Dysphagia after Nasopharyngeal Carcinoma Behav. Neurol. (IF 2.8) Pub Date : 2022-08-19 Honghong Li, Yong He, Xiaohuang Zhuo, Zongwei Yue, Xiaoming Rong, Yike Li, Yi Li, Lei He, Jinping Cheng, Dong Pan, Ruiqi Xue, Jinhua Cai, Jingru Jiang, Yongteng Xu, Yamei Tang
Introduction. Radiotherapy for patients with head and neck cancers raises their risk of aspiration pneumonia-related death. We aimed to develop and validate a model to predict radiation-associated aspiration pneumonia (RAP) among patients with dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC). Materials and Methods. A total of 453 dysphagic patients with NPC were retrospectively recruited
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Characterizing Cerebral Imaging and Electroclinical Features of Five Pseudohypoparathyroidism Cases Presenting with Epileptic Seizures Behav. Neurol. (IF 2.8) Pub Date : 2022-08-12 Zijuan Qi, Zhensheng Li, Quwen Gao, Li Dong, Jian Lin, Kairun Peng, Wei Xiang, Bingmei Deng
Objective. To characterize the cerebral imaging and electroclinical features and investigate their etiological contributions to seizures in pseudoparathyroidism (PHP). Methods. The clinical symptoms, biochemical imaging by magnetic resonance imaging (MRI) and computed tomography (CT) tests, and electroencephalogram (EEG) manifestations of five PHP patients with seizures were retrospectively collected
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The Mediating Role of Depression and Pain Catastrophizing in the Relationship between Functional Capacity and Pain Intensity in Patients with Fibromyalgia Behav. Neurol. (IF 2.8) Pub Date : 2022-07-16 Casandra I. Montoro, Carmen M. Galvez-Sánchez
Background. Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain condition characterized by widespread pain, sleep problems (i.e., insomnia and unrefreshing sleep), fatigue, cognitive, and emotional difficulties. Although pain has been proposed the factor mostly impacting in the FMS patients’ function, emotional and psychological FMS-associated factors are also known to exert a negative impact
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Behavioral Analysis of EEG Signals in Loss-Gain Decision-Making Experiments Behav. Neurol. (IF 2.8) Pub Date : 2022-07-15 Jiaquan Shen, Ningzhong Liu, Deguang Li, Binbin Zhang
Extraction and analysis of the EEG (electroencephalograph) information features generated during behavioral decision-making can provide a better understanding of the state of mind. Previous studies have focused more on the brainwave features after behavioral decision-making. In fact, the EEG before decision-making is more worthy of our attention. In this study, we introduce a new index based on the
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The Effects of Poria cocos on Rho Signaling-Induced Regulation of Mobility and F-Actin Aggregation in MK-801-Treated B35 and C6 Cells Behav. Neurol. (IF 2.8) Pub Date : 2022-07-12 Yi-Chyan Chen, Chang-Ti Lee, Fu-Ming Tsai, Mao-Liang Chen
Background and Aim. We recently investigated whether Poria cocos water extract modulates ketamine-induced Rho signaling regulation and reverses ketamine-inhibited cell mobility and F-actin reconstruction in B35 and C6 cells. Various studies have mentioned that drugs of abuse induce changes in neuronal plasticity in the brain’s reward circuitry. Modulations in neuronal plasticity are closely related
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Variability of Reaction Time as a Marker of Executive Function Impairments in Fibromyalgia Behav. Neurol. (IF 2.8) Pub Date : 2022-07-05 Stefan Duschek, Cristina Muñoz Ladrón de Guevara, María José Fernández Serrano, Casandra I. Montoro, Santiago Pelegrina López, Gustavo A. Reyes del Paso
In addition to chronic widespread pain and depression and anxiety symptoms, patients with fibromyalgia frequently experience cognitive problems. This study investigated executive functions in fibromyalgia via a Go/No-Go task. To obtain comprehensive information about performance, traditional and ex-Gaussian parameters of reaction time (RT) variability were used, in addition to speed and accuracy indices
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Identification of Alzheimer’s Disease Progression Stages Using Topological Measures of Resting-State Functional Connectivity Networks: A Comparative Study Behav. Neurol. (IF 2.8) Pub Date : 2022-07-04 Zhanxiong Wu, Jinhui Wu, Xumin Chen, Xun Li, Jian Shen, Hui Hong
Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely employed to examine brain functional connectivity (FC) alterations in various neurological disorders. At present, various computational methods have been proposed to estimate connectivity strength between different brain regions, as the edge weight of FC networks. However, little is known about which model is more sensitive