Floppy eyelids are usually asymmetrical, and more severe on the side the patient sleeps on. This has been related to the mechanical basis of this entity’s pathophysiology. Patients who exhibit floppy eyelid syndrome (FES) tend to suffer from obstructive sleep apnea and other sleeping disorder such as snoring; therefore, their spouses are likely to be found sleeping facing away from them. In this study

The aim was to examine the interrelationship between sleep quality of 1-month infants and mothers, mothers’ corresponding activities to infant’s night sleep, and mother’s mental health. A cross-sectional survey with self-reported questionnaire was conducted among 437 healthy mother–infant pairs at 1-month postpartum delivered at a maternal hospital in Tokyo. The main measurements were the presence

Perceived stress is strongly associated with sleep problems. Despite the evidence linking these variables, research examining the reciprocal relationships between them using non-recursive models, which include feedback loop between endogenous variables, is lacking. The main objective was to analyse if there is a bidirectional relation between perceived stress and insomnia symptoms with a model using

Inflammation activation is associated with adverse outcomes in patients with heart failure (HF). Sleep-disordered breathing (SDB) observed in 50% of patients with HF worsens the clinical outcome of HF, possibly through the exacerbation of inflammation. However, data on inflammation activation related to SDB are limited in patients with HF. We investigated the relationship between SDB severity and serum

Research and clinical practice have demonstrated that patients with insomnia are a heterogeneous population. As such, it is important to understand and differentiate the potential sub-groups among insomnia patients as well as individuals at risk for insomnia. Questionnaires completed by 291 students of both sexes and at risk for insomnia (FIRST scale score ≥ 22) were analyzed (age range 17–24 years)

The purpose of the study is to evaluate sleep disorders in dysmenorrhea patients and investigate the relationship between sleep disorders and anxiety and depression levels in these patients. This cross-sectional study included 55 primary dysmenorrhea patients who were admitted to the emergency department as well as 47 healthy control subjects. All participants were assessed using Beck Depression Inventory

Sleep disorders pose a serious threat to human, which may cause variety diseases. Recent reviews on the epidemiology examine that gastroesophageal reflux disease (GERD) has different levels of causality about asthma, chronic dry cough, sleep apnea, non-cardiac chest pain, chest tightness, and chronic bronchitis. The relationship between sleep disorders and GERD has been explained in various ways, but

Empathy is a crucial facet in providing healthcare to patients. Healthcare requires its workers to work extended shifts and provide 24/7 coverage, which can lead to increased sleepiness and changes in empathy. This study assessed how cognitive and affective empathy were affected by time of day, working a 12-h shift, and perceived sleepiness in emergency medical technicians. Results demonstrated that

Purpose To examine the psychometric properties of the Sleep Condition Indicator (SCI) using different psychometric approaches [including classical test theory, Rasch models, and receiver operating characteristics (ROC) curve] among patients with advanced cancer. Methods Through convenience sampling, patients with cancer at stage III or IV (n = 859; 511 males; mean ± SD age = 67.4 ± 7.5 years) were

A blackout on the island of Hokkaido occurred following a massive earthquake on September 6, 2018. This study analyzed the sleep pattern data of junior high school students on the night of the blackout in comparison to a normal night. Data were collected from 52 junior high school students from a school away from the earthquake’s epicenter but within the blackout area. Although the students normally

Sleep in children is essential for growth, emotional health and cognitive function. Although it has been described that poor sleep can seriously affect learning capacity, this relationship remains unclear. The purposes were to: (1) describe sleep patterns and sleep problems in schoolchildren; and (2) analyze the relationship between sleep quality and quantity and academic achievement. This study included

During long-term follow-up of the patients with obstructive sleep apnea syndrome (OSAS) under the positive airway pressure (PAP) therapy, it waits to be explored whether or when routine retitrations are indicated. We prospectively followed up 133 patients for 10 years to define which demographical or polysomnographic factors should be taken into account to determine the need for retitration. Patients

Although upper airway stimulation (UAS) is becoming an established therapy for obstructive sleep apnea (OSA) in Western countries, it is not available in Japan, where invasive procedures tend to be avoided, especially by women. We, therefore, performed surveillance concerning the preference for UAS among Japanese OSA patients receiving CPAP treatment. Preference for UAS and the reasons were obtained

Since sleep is under circadian and homeostatic regulation, the status of regulatory mechanisms can be known from daily activity patterns, including both sleep and wake states. Therefore, the relationship between their quantitative characterization and associated subjective QOL can be expected to provide practical knowledge for maintaining/improving QOL. An index quantifying the consistency of daily

The aim of this study was to evaluate the effect on patient anxiety and first-night effect (FNE) of a video modelling application, which has an important place in behavioural information practices. A total of 232 adolescent and adult patients with suspected obstructive sleep apnea were randomly separated into groups within two age ranges using the sealed envelope method. Group 1 (14–18 years, n: 40)

Sleep disturbances have multiple negative effects on psychological, social, and occupational aspects. The effects of sleep disturbances on the risk of taking sick leave was investigated in a meta-analysis. According to the PRISMA protocol, PubMed, Google Scholar, Scopus, and ResearchGate sites were searched by the researchers until October 2018. Studies with prospective design and also the articles

Insomnia disorder has known striking developments over the last few years. Partly due to advances in neuroimaging techniques and brain sciences, our understanding of insomnia disorder has become more fine-tuned. Besides, developments within psychological and psychiatric fields have contributed to improve conceptualization, assessment, and treatment of insomnia. In this paper, we present a list of promising

Investigation of sleep spindles’ oscillations is increasingly considered as a major avenue of inquiry in analyzing the microarchitecture of sleep. Previous studies highlight a strong mutual interaction between sleep and stress. In the present study, we investigated the effects of multiple stresses, provoked by animal immobilization in the narrow Plexiglas boxes with additional stress by placing some

Despite plenty of restless legs syndrome (RLS) studies conducted with hemodialysis patients, it has been scarcely studied in patients with predialysis chronic kidney disease (CKD). In the present study, we aimed to investigate the frequency of RLS in patients with nondialysis chronic kidney disease and explore the relationship between RLS with sleep quality, depression, pulse wave velocity (PWV), and

Poor sleep and excessive weight gain of pregnant women are associated with maternal outcomes. However, it’s unknown regarding their effects of each other in pregnant women. This cohort study aimed to identify the trajectories of sleep quality and their associations with excessive gestational weight gain during pregnancy. Data of 403 pregnant women were collected at three visiting points: early pregnancy

The purpose of this study was to investigate the association between sleep disturbances and dry eye syndrome (DES). 201 patients with DES were included in this study. Tear fluid break-up time (TBUT) and Schirmer I tests were performed. Patients with DES filled out Ocular Surface Disease Index (OSDI) questionnaire. The respondents completed the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity

The aim of this study was to examine the association between sleep duration and frailty in community-dwelling Turkish older adults and to determine whether this association varies depending on gender. A cross-sectional study was conducted from August 2013 to December 2013 with 905 individuals, representative of the aged population ≥ 60 years in community-dwelling elderly. Self-reported sleep duration

To examine whether insomnia disorder is associated with cognitive impairment in young and middle-aged Chinese adults. A case–control sample of 98 adults aged from 18 to 65 years old from Guangdong province underwent clinical history, physical examination, and cognitive assessments. We examined the trail-making test (TMT), basic symbol coding test (BASC), continuous performance task (CPT), category

Sleep-disordered breating (SDB), including obstructive sleep apnea–hypopnea syndrome (OSAS) is a clinical syndrome mainly characterized by recurrent upper airway collapse during sleep, which leads to snoring, respiratory disturbance, sleep interruption, hypoxemia, and subsequent chronic diseases. The options for intervention of OSAS include continuous positive airway pressure (CPAP), sleep surgery

The aim of this document was to provide a commentary on the AASM Manual for Scoring of Sleep and Associated Events in an Australasian context. A panel of Australasian sleep professionals developed the commentary. Each member was tasked with reviewing an assigned section and reporting back with potential AASM Manual clarifications and alterations. These suggestions were evaluated by the panel and ultimately

Adenosine signaling has profound effects on sleep, many of which depend on the adenosine A2A receptor (A2AR). Here, we compared the sleep architecture of adult male A2AR knockout (A2AR-KO) mice and wild-type littermates. While total time spent in each stage of wakefulness, non-rapid eye movement sleep (NREMS), and rapid eye movement sleep (REMS) was normal in A2AR-KO mice, the episode durations of

IntroductionThe purpose of this study was to assess the validity and reliability of the Persian version of the Cleveland Adolescent Sleepiness Questionnaire (CASQ) in Iranian adolescents. MethodsThe CASQ consists of 16 items measuring extreme sleepiness during the day in adolescents aged 11–17 years old. The questionnaire includes two dimensions: Sleepiness Statements and Alertness Statements. This

The Pittsburgh Sleep Quality Index (PSQI), a self-administrated questionnaire, is a frequently used instrument to assess sleep quality in clinical and non-clinical populations. The aim of the study was to evaluate the psychometric properties of the Arabic PSQI among patients diagnosed with cancer. A cross-sectional and descriptive correlational design was used with 369 patients with cancer completing

Sleep duration and quality are associated with many diseases. Evaluating the relationship between nutrient intake and sleep quality is important, because dietary factors play an important role in sleep quality. Short sleep duration which is associated with both metabolic disorders, obesity and, an irregular sleep pattern are thought to be related to an unhealthy diet. The recent literature has been

This review will trace the elements of neurostimulation for obstructive sleep apnea and details on its implementation, efficacy and safety, immediate clinical outcomes, and future prospects. The literature on upper airway neurostimulation was surveyed from July 2013 to July 2019, with a focus on the components of devices, evidence for clinical utility, and adverse events. Current technology is focused

Sleep disturbances, such as short sleep duration and insomnia, are core features of depression. However, it is unclear if sleep duration and insomnia have an interactive effect on depression severity or individual symptoms. Data were drawn from a community sample (N = 1007) containing responses on the Insomnia Severity Index, Patient Health Questionnaire–9 (PHQ-9), and average sleep duration. Regression

We investigated the relationship between sleep disturbances and 123I-meta-iodobenzylguanidine (MIBG)-uptake during myocardial scintigraphy in patients with Parkinson’s disease (PD). We studied consecutive PD patients who underwent MIBG scintigraphy at our institution. Collected data included Hoehn and Yahr (HY) stage, the heart/mediastinum (H/M) ratio of MIBG scintigraphy, Epworth Sleepiness Scale

This study examined the relationship between dissatisfaction with cutaneous body image and facial appearance with symptoms of insomnia whilst incorporating the mediating role of anxiety and/or depression after accounting for co-morbid sleep disorder symptoms. Participants (n = 241) completed online measures assessing insomnia symptoms, anxiety and depression symptoms, and satisfaction with cutaneous

The purpose of this study was to explore the impact that portable electronic device use in bed after lights out has on sleep/wake behaviour within an adult population. Specifically, this study aimed to (1) identify patterns of use of electronic devices in bed; (2) examine the relationship between electronic device use in bed and sleep/wake behaviour; and (3) examine the impact of demographic variables

A 39-year-old married woman was referred to a psychiatry outpatient clinic for treatment of major depressive disorder (MDD). The dose of zolpidem she had been taking had increased to more than 500 mg/day and, therefore, she was hospitalized with the aim of zolpidem detoxification. On admission, her serum zolpidem level was 1550 ng/mL, and this dropped to less than one (ng/mL) within 50 h. However,

Scientific research on the benefits of the Mahjong card game and social activity for sleep remains limited among older adults in China, although these two leisure behaviors are common among Chinese older adults. This study aims to examine this topic of interest in a single research effort. Applying panel data from the Chinese Longitudinal Healthy Longevity Survey from 4718 participants, a nationally

Bright light (BL) therapy is clinically utilized for treatment of sleep–wake disorders through the manipulation of circadian oscillation. It is also extended to depressive disorders including seasonal affective disorder through emotional regulation. Recently, it has been suggested that BL facilitates memory encoding and consolidation via another psychophysiological mechanism of perceptual information

There is a paucity of studies investigating how sexual activity is perceived to influence sleep, despite conceptions about significant gender differences regarding this issue. In all, 4000 persons, aged between 18 and 55 years, were randomly drawn from the Norwegian Population Registry and invited to participate in a postal survey. The respondents were asked how sexual activity with another person

Assessment of sleep is an important determinant of health. Moreover, sleep assessment is quite difficult in elderly people; getting consent for participation in the study, spending more time due to cognitive and communicative disruptions, having difficulties in accessing to individuals, and higher withdrawal rate of elderly people than adults occur as additional difficulties. The objective of the study

To determine the relationship of specific macro- and micro-nutrients and food groups with sleep duration and sleep quality in adults. This cross-sectional descriptive study was conducted on 2446 adults aged between 20 and 64 years in Turkey. The participants’ socio-demographic characteristics, anthropometric measurements, and dietary intake (24-h recall) were taken. The Pittsburgh Sleep Quality Index

Cocaine administration can be disruptive to sleep. In compulsive cocaine users, sleep disruption may be a factor contributing to relapse. The effects of cocaine on sleep, particularly those produced by low doses, have not been extensively studied. Low dose cocaine may stimulate brain reward systems that are linked to the liability of abusing of this drug. This study was designed to assess the effects

Although exercise is widely believed to improve sleep, experimental evidence has found acute and chronic exercise to exert only modest effects on subsequent sleep. However, these studies are limited in that they have primarily used good sleepers (floor/ceiling effects). In contrast to experimental studies, epidemiologic studies have consistently reported significant positive associations between self-reported

The objective of this study was to investigate the reliability and validity of the Pittsburgh Sleep Quality Index (PSQI) in a non-clinical sample consisting of younger and older adults. There has been little research validating the PSQI with respect to multinight recording as with actigraphy, and more validation is needed in samples not specifically selected for clinical disturbance. Also, the degree

The antidepressant and sleep-promoting effects of light exposure might be useful for treating age-related mood and sleep disorders. In view of recent evidence suggesting beneficial effects of morning light, this study examined the associations of mood and sleep with morning light exposure, 24 h environmental illumination, and the degree to which the volunteers' bedroom windows were covered in the morning

The purposes of this study were: (1) to confirm the prevalence of sleep-disordered breathing (SDB) in Japanese children using nocturnal pulse oximetry (NPOx) as a screening tool and (2) to examine what kind of parameters are suitable for the evaluation of SDB in children. We conducted a study of 99 children between 4 and 15-year-old and obtained their demographic characteristics and the presence of

Sleep hygiene education involves promoting good sleep habits in all aspects of lifestyle and behavior. In this study, we evaluated the effects of a sleep hygiene education program for Japanese high school students who did not have insomnia symptoms.Tenth-grade students (N = 2815; intervention, n = 1347; control, n = 1468) from 16 high schools in a provincial city in Japan participated in this cluster-controlled

We report an adolescent case of malignant brain tumor who presented with an irregular sleep–wake cycle as the first significant clinical symptom. The patient was referred to us with a 1-year history of irregular sleep–wake cycle. Subsequently, she was diagnosed with a brain tumor in left temporal lobe, which severely compressed the brain stem. Postoperatively, her sleep–wake cycle normalized, suggesting

Narcoleptics tend to have a low quality of life (QoL). Few studies have compared QoL in narcolepsy against other sleep disorders. The purpose of this study was to investigate QoL and its influential factors in narcolepsy patients compared to obstructive sleep apnea (OSA) with somnolence and primary insomnia. We enrolled 63 narcoleptics (33 type 1, 30 type 2), 49 patients with OSA with somnolence, and

Daytime sleepiness is common in college students. In women, daytime sleepiness increases in the late-luteal phase compared with the follicular phase. In addition, women with premenstrual dysphoric disorder (PMDD), the severest form of premenstrual syndrome (PMS), experience severer daytime sleepiness than healthy women do. To date, daytime sleepiness has not been compared between women with PMDD and

Morningness (a preference for earlier rise and bed times) is associated with well-being, better sleep quality, and positive affect, while eveningness is associated with poor sleep quality, negative mood, maladaptive behaviours, and psychological disorder. The current study investigated: (1) whether eveningness is associated with more maladaptive metacognitive beliefs; (2) whether maladaptive metacognitive

The relationship between sleep and brain lesions remains unknown in patients with multiple sclerosis (MS) and is currently under investigation. Sleep deprivation and reduction in the quality of sleep occur as a result of the direct involvement of the specific central nervous system structure. Therefore, we investigated the relationship between demyelination locations and sleep parameters such as sleep

Relapse rates are high in cigarette smokers attempting to quit. Research suggests disturbed sleep may be associated with smoking resumption. We investigated nighttime sleep and daytime sleepiness in smokers, before and during a quit attempt without treatment. Fourteen smokers (16.2 ± 6.2 cigarettes per day; ages 27.6 ± 5.6 years) spent three consecutive nights in a sleep laboratory including polysomnographic

Neurovascular coupling (NVC), the transient regional hyperemia following the evoked neuronal responses, is the basis of blood oxygenation level-dependent techniques and is generally adopted across physiological conditions, including the intrinsic resting state. However, the possibility of neurovascular dissociations across physiological alterations is indicated in the literature. To examine the NVC

The aim of the study was to evaluate whether there was a problem in the interneuronal junctions of patients with central sleep apnea using the blink reflex test. Twenty-one (21) patients with central type apneas and/or hipopneas and 21 controls were recruited. The blink reflex test was performed and R1, R2 and contralateral R2 (R3) wave values of both groups were recorded in milliseconds (ms). The

The purpose is to evaluate the effect and safety of ramelteon 8 mg/day for 8 weeks in the treatment of insomnia in patients with concurrent depression in an exploratory manner. This phase 4, open-label, exploratory study included outpatients aged 20 to < 65 years with sleep-onset insomnia and major depressive disorder taking stable antidepressant medication. Following a 1-week run-in, 26 eligible patients

Misalignment between an individual’s circadian phase and his/her environment due to social imposition is called social jetlag (SJL). SJL has emerged as a public health concern, as it contributes to an unhealthy lifestyle and adverse health outcomes. This study aimed to elucidate the percentage of SJL in a large Japanese population using the Japanese version of the Munich ChronoType Questionnaire (MCTQ)

Individuals with chronic insomnia tend to increase their amount of time in bed (TIB) to secure more opportunity for sleep, which in turn, may aggravate and perpetuate the condition. It remains unclear whether this behavioral feature of clinical insomniacs, which are targets of cognitive–behavioral therapy for insomnia, can be generalized to individuals with sleep disturbance in the general population

This study examined the prevalence of depression and anxiety symptoms in OSA patients, and predictors of mood disturbance in male and female patients. N = 344 consecutive OSA patients (mean age 51.6 SD 14.1 years, 176 women) completed the Epworth Sleepiness Scale and the Hospital Anxiety and Depression Scale. 42.3% of females reported significant depressive symptoms compared to 32.7% of males, and

We conducted a multicenter, open-label, observational study to evaluate the effectiveness and safety of ramelteon in patients with insomnia, and patient characteristics affecting treatment response in routine clinical practice. Eligible patients were aged ≥ 20 years, had a diagnosis of insomnia with difficulty falling asleep, and were scheduled to receive ramelteon 8 mg/day for 12 weeks. The primary

There exist inconsistent findings about the relation between cosleeping and sleep problems in children. We conducted a meta-analysis to assess these relations and compared their cross-cultural differences. We searched the EMBASE, PsycARTICLES, PsycINFO, PubMed, ScienceDirect, and Web of Science databases. A random effect model was used, and subgroup analysis by culture group was performed. By including