Previous investigations have implicated the basolateral amygdala (BLA) epigenetic mechanisms in the pathophysiology of depression. SIRT1 is a NAD+-dependent class III histone deacetylase, widely expresses in BLA. However, epigenetic mechanisms in the BLA under the regulation of SIRT1 in the depression are largely uncharacterized. Under the chronic unpredictable chronic mild stress (CUMS) mouse model

Dopaminergic neurons (DA neurons) are controlled by multiple factors, many involved in neurological disease. Parkinson’s disease (PD) motor symptoms are caused by the demise of nigral DA neurons, leading to loss of striatal dopamine (DA). Here, we measured DA concentration in the dorsal striatum of 32 members of Collaborative Cross (CC) family and their 8 founder strains. Striatal DA varied greatly

Mutations in the disrupted in schizophrenia-1 (DISC1) gene are associated with an increased risk of developing psychological disorders including schizophrenia, bipolar disorder, and depression. Assessing the impact of knocking out genes, like DISC1, in animal models provides valuable insights into the relationship between the gene and behavioral outcomes. Previous research has relied on mouse models

In the published article of Song et al1, the grant Natural Science Foundation of Hunan Province of China (2018JJ2035) was missing in the Funding information and Acknowledgments section. The Funding information and Acknowledgments should read:

In the original publication of the article by Mineur et al. [1], the surname of the second was misspelled. The name of the second author should be Charlotte Ernstsen. This has since then be amended in the online version of the article.