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HEMORRHAGIC STROKE AS INSPIRATION FOR POETRY: THE CASE OF ALFRED TENNYSON, ARTHUR HENRY HALLAM AND IN MEMORIAM A.H.H. Eur. Neurol. (IF 2.4) Pub Date : 2023-11-21 Matheus Pedro
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Continuous versus routine electroencephalography in the intensive care unit: a review of current evidence. Eur. Neurol. (IF 2.4) Pub Date : 2023-11-10 Helene Fenter,Andrea O Rossetti,Isabelle Beuchat
Background Electroencephalography has long been used to detect seizures in patients with disorders of consciousness. In recent years, there has been a drastically increased adoption of continuous EEG (cEEG) in the ICUs. Summary Despite the development of increasingly performant imaging techniques and several validated biomarkers, EEG remains central to clinicians in the intensive care unit, and is
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CSF White Blood Cell Count in Diagnosis of Neurosyphilis. Eur. Neurol. (IF 2.4) Pub Date : 2023-11-07 Duyu Ding
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Prediction of MCI progression to AD based on DTI-derived diffusion parameters: construction and validation of a nomogram. Eur. Neurol. (IF 2.4) Pub Date : 2023-11-03 Xuefei Cheng,Dongxue Li,Jiaxuan Peng,Zhenyu Shu,Xiaowei Xing
OBJECTIVE To construct and validate a nomogram that combines diffusion tensor imaging (DTI) parameters and clinically relevant features for predicting the progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD). METHOD A retrospective analysis was conducted on the MRI and clinical data of 121 MCI patients, of whom 32 progressed to AD during a four-year follow-up period. The MCI patients
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Cerebral microbleeds are associated with widespread blood-brain barrier leakage. Eur. Neurol. (IF 2.4) Pub Date : 2023-10-26 Yue Li,Man Li,Long Zuo,Xuanting Li,Yutong Hou,Wenli Hu
INTRODUCTION The pathogenesis of cerebral microbleeds (CMBs) is incompletely understood but blood-brain barrier (BBB) leakage may play a key role. This study aimed to investigate the relationship between compromised BBB integrity and CMBs as well as cognitive function. METHODS Ninety-seven participants were enrolled in this cross-sectional study, involving 24 CMBs patients. Dynamic Contrast-Enhanced
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The usefulness of cerebrospinal fluid white blood cell count in neurosyphilis. Eur. Neurol. (IF 2.4) Pub Date : 2023-10-23 John L Frater
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Exploring shared genetic signatures of Alzheimer's disease and multiple sclerosis: a bioinformatic analysis study. Eur. Neurol. (IF 2.4) Pub Date : 2023-10-17 Dasen Yuan,Bihui Huang,Meifeng Gu,Bang-E Qin,Zhihui Su,Kai Dai,Fu-Hua Peng,Ying Jiang
BACKGROUND Many clinical studies reported the coexistence of Alzheimer's disease (AD) and multiple sclerosis (MS), but the common molecular signature between AD and MS remains elusive. The purpose of our study is to explore the genetic linkage between AD and MS through bioinformatic analysis, providing new insights into the shared signatures and possible pathogenesis of two diseases. METHODS The common
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Long-term efficacy and safety of low-dose rituximab in patients with refractory myasthenia gravis. Eur. Neurol. (IF 2.4) Pub Date : 2023-09-30 Jingru Ren,Jianchun Wang,Ran Liu,Yunyi Jin,Jing Guo,Yan Yao,Jingjing Luo,Hongjun Hao,Feng Gao
Introduction Rituximab is a monoclonal chimeric antibody against CD20+ B cells. We aimed to assess the long-term efficacy and safety of CD20+ B cell-guided treatment with low-dose rituximab in refractory myasthenia gravis patients. Methods Patients with refractory myasthenia gravis treated with rituximab for more than 2 years were included. Rituximab was administered when CD20+ B cells were greater
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Endovascular Treatment plus Medical Treatment versus Medical Treatment Alone in Ischemic Stroke: A Systematic Review and Meta-Analysis. Eur. Neurol. (IF 2.4) Pub Date : 2023-09-25 Ahmad A Toubasi,Thuraya N Al-Sayegh,Farah H Albustanji,Layla M Al-Harasis
INTRODUCTION This study was conducted to assess the hypothesis that endovascular treatment in addition to medical treatment improve stroke mortality and post-stroke disability. METHODS In this systematic review and meta-analysis, the studies were included if they were randomized controlled trials in design and compared between endovascular treatment and medical therapy versus medical therapy alone
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Clinical manifestations of subjective sleep disorders in Chinese patients with Parkinson's disease and their relationship with dopaminergic drugs. Eur. Neurol. (IF 2.4) Pub Date : 2023-09-06 Dong-Dong Wu,Jing He,Kai Li,Huijing Liu,Ying Jin,Wei DU,Xinxin Ma,Yunfei Long,Shuhua Li,Wen Su,Haibo Chen
INTRODUCTION Sleep disorders are common in Parkinson's disease (PD) and significantly impact quality of life. Herein, we surveyed the incidence and severity of sleep disorders in Chinese PD patients and observed their relationship with dopaminergic drugs. METHODS We collected the demographic and disease information of 232 PD patients. The incidence and severity of sleep disorders were surveyed with
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André-Thomas (1867-1963), Initiator of Neonatal Neurology. Eur. Neurol. (IF 2.4) Pub Date : 2023-09-01 Olivier Walusinski
After a brilliant career as a clinician and anatomopathologist, André-Thomas (1868-1963) spent the last 30 years of his life validating the components of neurological examinations of newborns and infants. This novel approach was developed through long examinations of several hundreds of normal and sick children, notably those with anencephaly. By combining his vast knowledge of physiology with the
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Management of Status Epilepticus by Different Pediatric Departments: Neurology, Intensive Care, and Emergency Medicine. Eur. Neurol. (IF 2.4) Pub Date : 2023-08-30 Özge Dedeoglu,Halise Akça,Serhat Emeksiz,Ayşe Kartal,Neşe Çıtak Kurt
INTRODUCTION The aim of this study was to explore the differences in status epilepticus (SE) management among pediatric neurology, emergency medicine, and intensive care specialists in Turkey. METHODS A 22-item questionnaire regarding first-, second-, and third-line management strategies of SE including demographic characteristics and common etiologies according to the specialty of participants was
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Resolving the Smoking Paradox: No Evidence for Smoking-Induced Preconditioning in Large Vessel Occlusion Stroke. Eur. Neurol. (IF 2.4) Pub Date : 2023-08-10 Roni E Widmer,Andrea Bink,Janne Hamann,Lisa Herzog,Mohamad El Amki,Hakan Sarikaya,Zsolt Kulcsar,Andreas R Luft,Susanne Wegener
INTRODUCTION Smoking is an established risk factor for stroke. However, several studies have reported a better outcome after stroke for patients who smoke. According to this "smoking paradox" hypothesis, smoking might promote less severe strokes, higher collateral scores, and smaller infarct cores. METHODS In this retrospective study, we screened data of 2,980 acute ischemic stroke patients with MCA-M1
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The diagnostic performance of laboratory tests of neurosyphilis: a systematic review and network meta-analysis. Eur. Neurol. (IF 2.4) Pub Date : 2023-08-07 Duyu Ding,Junhua Gao,Wei Zhang,Dongmei Xu
INTRODUCTION The gold standard for diagnosing Neurosyphilis (NS) is currently unavailable; various laboratory parameters in cerebrospinal fluid (CSF) and blood can assist in the diagnosis. METHODS PubMed, Embase, and the Cochrane Library were searched. Studies utilizing laboratory tests to assist in the diagnosis of NS were included. The pooled indicators for diagnostic performance and their respective
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Cerebellar Volume Reduction in Patients with Isolated REM Sleep Behavior Disorder: Evidence of a Potential Role of the Cerebellum. Eur. Neurol. (IF 2.4) Pub Date : 2023-08-01 Dong Ah Lee,Ho-Joon Lee,Kang Min Park
INTRODUCTION In this study, we aimed to investigate changes in the total cerebellar volume, subdivisions of the cerebellar volume, and intrinsic cerebellar network in patients with isolated rapid eye movement (REM) sleep behavior disorder (iRBD) compared to healthy controls. METHODS We enrolled patients with newly diagnosed iRBD and healthy controls who had no structural lesions according to their
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Interferon Beta-1a versus Glatiramer Acetate: Changes of Innate Immunity in a Group of Women with Multiple Sclerosis. Eur. Neurol. (IF 2.4) Pub Date : 2023-07-20 Marek Peterka,Martin Valis,Ondrej Soucek,Jan Krejsek,Lukáš Sobisek,Ilona Sejkorova,Blanka Klimova,Pavel Stourac,Zbysek Pavelek,Michal Novotny
INTRODUCTION Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating disease that secondarily leads to axonal loss and associated brain atrophy. Disease-modifying drugs (DMDs) have previously been studied for their ability to affect specific immunity. This study investigates the effect of interferon beta-1a (INF) and glatiramer acetate (GA) administration on changes in innate immunity
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When Cerebral Microbleed Meets Dilated Perivascular Space in Cerebral Amyloid Angiopathy. Eur. Neurol. (IF 2.4) Pub Date : 2023-07-05 Dimitri Renard,Anne Wacongne
none.
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Association of Pesticide Exposure with Cognitive Function in Farmers. Eur. Neurol. (IF 2.4) Pub Date : 2023-06-26 Ismail Setyopranoto,Abdul Gofir,Laxmiprita Pusparani Rahardjo,Andre Stefanus Panggabean,Ery Kus Dwianingsih,Indarwati Setyaningsih,Cempaka Thursina Srie Setyaningrum,Sri Sutarni,Rusdy Ghazali Malueka
INTRODUCTION Organophosphate and carbamate are two types of pesticides that can induce cholinesterase suppression in humans. These lead to poisoning symptoms including muscle paralysis and respiratory depression in acute settings. In chronic settings, the mechanism of organophosphate and carbamate poisoning is still openly discussed. Accordingly, this study aimed to identify any correlations between
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Migraine Attacks Triggered by Ingestion of Watermelon. Eur. Neurol. (IF 2.4) Pub Date : 2023-06-15 Raimundo Pereira Silva-Néto,Gabriela Leal Bezerra,Natália Rebeca Alves Araújo,Sângela Fernandes Silva,Suyanne Kássia Soares Pereira,Layana Karine Farias Lima,Adriana Almeida Soares,Luciano Silva Lopes
INTRODUCTION Ingesting some foods can trigger headache attacks in migraine patients. Diet-sourced citrulline activates the l-arginine-nitric oxide pathway, acting on the pathophysiology of migraine. METHODS The study was a clinical trial, interventional, controlled, and with group comparison. The sample was non-random, composed of 38 volunteers with migraine and 38 without headache (control). Both
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Imaging, Genetic, and Pathological Features of Vascular Dementia. Eur. Neurol. (IF 2.4) Pub Date : 2023-06-03 Xiaoni Yang,Chao Chen,Aishuai Wang,Changsheng Li,Guangqing Cheng
BACKGROUND Over the past decades, marked progress has been made in detecting vascular dementia (VD) both through maturation of diagnostic concepts and advances in brain imaging, especially MRI. We summarized the imaging, genetic, and pathological features of VD in this review. SUMMARY It is a challenge for the diagnosis and treatment of VD, particularly in patients where there is no evident temporal
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Interleukin-33 as a biomarker affected intrathecal synthesis of immunoglobulin in NMOSD and MOGAD Eur. Neurol. (IF 2.4) Pub Date : 2023-04-26 Mengyu Wang, Dongxia Xia, Lin Sun, Jianzhong Bi, Keqin Xie, Pin Wang
Introduction: The purpose of this study was to analyze IL-33 maybe as a biomarker especially with respect to intrathecal immunoglobulin (IgG) synthesis which was involved in the immune -mediated process in the demyelinating disease of the central nervous system. Methods: We aimed to determine the risk association of the serum and CSF levels of IL-33 in AQP4+NMOSD patients and MOGAD patients compared
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Close your eyes and see – stroke sequelae versus functional neurological disorder in a physician Eur. Neurol. (IF 2.4) Pub Date : 2023-04-20 E. Jennifer Weil, Harold Keyserling, Burt Feuerstein, Olwen Murphy
The first author was a left-handed, 51-year-old nephrologist who experienced a neurologic event. She underwent neurosurgery complicated by hemorrhage. Post-operatively, she developed persistent vertigo and unilateral tongue pain which persisted for over five years. Early neuroimaging revealed expected encephalomalacia but no neuroanatomical basis for my symptoms. A functional neurological disorder
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Association between respiratory function and motor function in different stages of Parkinson’s disease Eur. Neurol. (IF 2.4) Pub Date : 2023-04-17 Chong Xi, Xiao-Chen Bai, Ce Li, Wei-Ning Wang, Shan Tian, Yi-Lin Tang, Bo Shen, Jian Wang, Yi-Min Sun, Yu-Lian Zhu
Introduction: Respiratory dysfunction in patients with Parkinson’s disease (PD) could present in the early stage and worsen in the late stages. These changes could be a factor affecting the ability of daily living and quality of life of patients with PD. The primary objective of this study was to assess the respiratory function and its association with motor function in patients with different stages
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Efficacy and safety of ticagrelor versus aspirin and clopidogrel for stroke prevention in patients with vascular disease: a systematic review and meta-analysis Eur. Neurol. (IF 2.4) Pub Date : 2023-04-17 Xibo Ma, Danfeng Li, Shihua Liu, Yan Chen, Ping Zhong
Introduction: Currently, it is still controversial to treat stroke with ticagrelor alone. The purpose of our study was to systematically review and analyze the efficacy and safety of ticagrelor on cerebrovascular outcomes in patients with vascular risk factors. Methods: The PubMed, Cochrane Library, and EMBASE databases were systematically searched using the keywords stroke, ticagrelor, clopidogrel
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Neurologic Images Popeye sign: look at the heart (and the nerves) Eur. Neurol. (IF 2.4) Pub Date : 2023-03-31 Angela Romano, Valeria Guglielmino, Maria Ausilia Sciarrone, Francesca Vitali, Marco Luigetti
Abstract is not required for Neurologic Images
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Relationship between peripheral blood inflammatory factors and prognosis of subarachnoid hemorrhage: A meta-analysis Eur. Neurol. (IF 2.4) Pub Date : 2023-03-27 Lu Peng, Xiang Li, Hang Li, Yi Zhong, Jinrong Lian, Heng Gao, Gang Chen
Background: Subarachnoid hemorrhage (SAH) is a severe cerebrovascular event with high mortality and disability rate. Neuroinflammation is involved in the brain injury after SAH, but the exact association between SAH progression and peripheral blood inflammatory factors is unknown. Therefore, to determine the relationship between inflammatory factors and the prognosis of SAH, we performed a meta-analysis
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Delirium and dementia in the elderly: sometimes associated or always together? Eur. Neurol. (IF 2.4) Pub Date : 2023-03-23 Orso Bugiani
Background – In the elderly, the association of delirium and dementia can cause diagnostic problems because they share the same symptom of confusion. Delirium is often misdiagnosed as dementia and treated inappropriately, ignoring that it could be successfully addressed, which can lead to increased health risks up to death. Summary – Confusion indicates that functional reserve fails to compensate for
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Berlin Bowel Bothers: Might Adolf Hitler’s Gut Problems Have Been Parkinson-Related? Eur. Neurol. (IF 2.4) Pub Date : 2023-03-15 Milan Beckers, Peter J. Koehler, Geert J.A. Wanten, Bastiaan R. Bloem
It has been argued that Adolf Hitler (1889 – 1945) had Parkinson’s disease. He also experienced several gastrointestinal symptoms, for which various explanations have been sought, both contemporaneously and by later authors. In this Historical Note, a possible relationship between Hitler’s Parkinson’s disease and his gastrointestinal symptoms is explored. Specifically, we posit the hypothesis that
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Summary of safety and efficacy of COVID-19 vaccination in patients with multiple sclerosis Eur. Neurol. (IF 2.4) Pub Date : 2023-03-04 Eva Pernicová, Petra Macounová, Martin Krsek, Rastislav Maďar
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic represents one of the most challenging issues that have recently influenced everyday life in countries all over the world. Understanding the risk of this disease is of high importance in patients with multiple sclerosis (MS) as they represent a vulnerable population through their treatment with disease-modifying therapies
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A simplified clinical prediction rule for prognosticating dependent daily living in patients with thoracic spinal cord injury: A multicenter nationwide Japan registry study Eur. Neurol. (IF 2.4) Pub Date : 2023-03-03 Takeshi Imura, Tomonari Hori, Ryo Tanaka
Introduction Clinical prediction rule (CPR) using decision tree analysis is able to show the branching of the variables under consideration in a clear, hierarchical manner, including specific reference values, which can be used as classifiers in clinical practice. However, CPR developed by decision tree analysis for predicting the degree of independent living of patients with thoracic spinal cord injury
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Minor salivary gland biopsy for the diagnosis of neurosarcoidosis Eur. Neurol. (IF 2.4) Pub Date : 2023-03-01 Nicolas Fournier, Yvan Jamilloux, Mathieu Gerfaud-Valentin, Nathalie Streichenberger, Sandra Vukusic, Romain Marignier, Géraldine Androdias, Pascal Seve
Introduction: The definite diagnosis of neurosarcoidosis is challenging since it requires a compatible histology of the nervous system. When neurosarcoidosis is suspected, other systemic manifestations are investigated to confirm the diagnosis. A minor salivary gland biopsy (MSGB) is often performed since it is minimally invasive. The objective of the present study was to assess its performance for
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Development of Acute Transverse Myelitis following COVID-19 Infection: A Review on the Potential Pathways Eur. Neurol. (IF 2.4) Pub Date : 2023-03-01 Majid Reza Farrokhi, Farideh Iravanpour, Negar Nejabat
Background: Acute transverse myelitis (ATM) is a rare neurological disorder in adults characterized by localized inflammation of gray and white matter in one or more contiguous spinal cord segments in the absence of a compressive injury. Several reports have connected the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the pathophysiology of ATM. Summary: Direct invasion of the spinal
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Long-lasting COVID-associated brain fog; a follow-up study Eur. Neurol. (IF 2.4) Pub Date : 2023-02-24 Ali A. Asadi-Pooya, Mina Shahisavandi, Hamid Nemati, Afrooz Karimi, Anahita Jafari, Sara Nasiri, Seyyed Saeed Mohammadi, Meshkat Nemati, Zahra Rahimian, Hossein Bayat
Background: We investigated the longevity of COVID-associated brain fog in patients who have survived the COVID-19. Methods: This was a follow-up study of 2,696 adult patients with COVID-19 from our previous study (doi: 10.1002/jmv.27404). We selected every other patient in our database. The follow-up data were collected during a phone call to the participants in January-February 2022 (11 months after
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NEFL-RELATED CHARCOT-MARIE TOOTH DISEASE DUE TO P440L MUTATION IN TWO ITALIAN FAMILIES: EXPANDING THE PHENOTYPE AND DEFINING MODULATING FACTORS Eur. Neurol. (IF 2.4) Pub Date : 2023-02-21 Antonio Petrucci, Ludovico Lispi, Matteo Garibaldi, Erika Frezza, Francesca Moro, Roberto Massa, Filippo Maria Santorelli
Mutations in the neurofilament polypetide light chain (NEFL) gene account for <1 % of all forms of Charcot-Marie-Tooth (CMT) diseases, and present with different phenotypes, including demyelinating, axonal and intermediate neuropathies and with diverse pattern of transmission, with dominant and recessive inheritance being described. Here we present clinical and molecular data in two new unrelated Italian
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The Path of Discovery and Opioid-associated Amnestic Syndrome in “The Memory Thief”. Book Review Eur. Neurol. (IF 2.4) Pub Date : 2023-02-10 Mason Bennett
N/A
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Advances in Futile Reperfusion following Endovascular Treatment in Acute Ischemic Stroke due to Large Vessel Occlusion Eur. Neurol. (IF 2.4) Pub Date : 2023-02-08 Liyuan Wang, Yunyun Xiong
Background: Futile reperfusion (FR) is becoming an urgent issue for acute ischemic stroke patients who underwent endovascular treatment (EVT). Although the recanalization rate has improved after EVT, it is far from translating to increased tissue reperfusion and functional independence. Summary: Many underlying mechanisms including the “no-reflow” phenomenon, poor collateral flow, venous dysfunction
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NOTCH4 Single-Nucleotide Polymorphism Is Associated with Brain Arteriovenous Malformation in a Chinese Han Population Eur. Neurol. (IF 2.4) Pub Date : 2023-02-01 Ming Zhong, Jianbo Zhang, Zhenjun Li, Ziying Liu, Haiyan Fan, Hengxian Su, Hongliang Meng, Xin Zhang, Xifeng Li, Chuan-Zhi Duan, Xuying He
Introduction: Brain arteriovenous malformations (BAVMs) are high-flow intracranial vascular malformations characterized by the direct connection of arteries to veins without an intervening capillary bed. They are one of the main causes of intracranial hemorrhage and epilepsy, although morbidity is low. Angiogenesis, heredity, inflammation, and arteriovenous malformation syndromes play important roles
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Muybridge, Dercum, and the Early Use of Photography in the Study of Psychogenic Non-Epileptic Seizures Eur. Neurol. (IF 2.4) Pub Date : 2023-01-25 Richard Ho, Enrique J. Carrazana
The impact of the collaboration between photographer Eadweard Muybridge and neurologist Francis Dercum is detailed within the context of a photographic study of an artificially induced psychogenic non-epileptic seizure. Their contribution served as inspiration to other contemporary European neurologists and photographers to use motion photography to further understand psychogenic neurological disorders
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Nonpainful Trigeminal Neuropathy Associated with a Solitary Pontine Lesion: A Case Series Eur. Neurol. (IF 2.4) Pub Date : 2023-01-23 Hüseyin Nezih Özdemir, Neşe Çelebisoy
A solitary pontine lesion (SPL) is a single brainstem lesion on the trigeminal nerve pathway without any other central nervous system lesion. This research aimed to investigate the demographic and clinical features of nonpainful TNO patients with SPL and identify the most frequently affected anatomical areas using lesion mapping techniques. Demographic and clinical features were retrospectively reviewed
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Identifying the Basic Dimensions of Medication-Triggered Impulsive Compulsive Behaviours in Parkinson’s Disease Eur. Neurol. (IF 2.4) Pub Date : 2023-01-19 Nicky Edelstyn, Elisa Di Rosa, Alice Martini
Background: This review article integrates findings from published behavioural and neuroimaging studies of impulsive-compulsive behaviours (ICBs) in Parkinson’s disease, with the aim of identifying the basic correlates of these problematic and distressing behaviours. The underlying premise is that for any feature to be a reliable marker of ICBs, it should be evident across multiple levels of analyses
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Microcirculation No-Reflow Phenomenon after Acute Ischemic Stroke Eur. Neurol. (IF 2.4) Pub Date : 2023-01-06 Jiaqi Hu, Ding Nan, Yuxuan Lu, Zhenyu Niu, Yingying Ren, Xiaozhong Qu, Yining Huang, Haiqiang Jin
Background: The no-reflow phenomenon refers to a failure to restore normal cerebral microcirculation despite brain large artery recanalization after acute ischemic stroke, which was observed over 50 years ago. Summary: Different mechanisms contributing to no-reflow extend across the endovascular, vascular wall, and extravascular factors. There are some clinical tools to evaluate cerebral microvascular
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The Effects of Neuromodulators on Spasticity, Balance, and Gait in Patients with MS: A Systematic Review and Meta-Analysis Study Eur. Neurol. (IF 2.4) Pub Date : 2023-01-05 Alireza Emadi, Sara Halakoo, Cyrus Taghizadeh Delkhoush, Fatemeh Ehsani
Introduction: Multiple sclerosis (MS) is a common neurological disorder in societies. The most common symptoms in patients with MS are gait disorders and spasticity. Pharmacological therapies have mild therapeutic influence with more side effects for management of these symptoms. There is evidence that neuro-rehabilitation techniques have more appropriate effects rather than pharmacological therapies
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Radiological Disease Activity in Secondary Progressive Multiple Sclerosis Eur. Neurol. (IF 2.4) Pub Date : 2023-01-03
Introduction: MRI activity is less frequent among secondary progressive multiple sclerosis (SPMS) patients. In the current study, we aimed to identify SPMS patients with higher radiological disease activity (RDA) and determine their clinical characteristics. Methods: We evaluated the occurrence of RDA in SPMS patients followed at the Sheba Multiple Sclerosis Center between January 1, 2015, and December
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Radiological Disease Activity in Secondary Progressive Multiple Sclerosis. Eur. Neurol. (IF 2.4) Pub Date : 2023-01-03 Daniela Noa Zohar,David Magalashvili,Sapir Dreyer-Alster,Chen Hoffmann,Gil Harari,Mark Dolev,Anat Achiron
INTRODUCTION MRI activity is less frequent among secondary progressive multiple sclerosis (SPMS) patients. In the current study, we aimed to identify SPMS patients with higher radiological disease activity (RDA) and determine their clinical characteristics. METHODS We evaluated the occurrence of RDA in SPMS patients followed at the Sheba Multiple Sclerosis Center between January 1, 2015, and December
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Visual Working Memory Capacity in Patients with Temporal Lobe Glioma Eur. Neurol. (IF 2.4) Pub Date : 2022-12-21 Shengyuan Ni, Peng Chen, Yang Yang, Dejun Bao, Rui Zhang, Qi Pang
Introduction: Working memory (WM) refers to the temporary storage and manipulation of information. Short-term memory storage can be divided into separate subsystems for verbal information and visual information. We explored the capacity of visual WM in patients with temporal lobe glioma. Methods: In this study, we assessed 30 patients with temporal lobe glioma and 30 healthy controls (HCs) using a
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Migraine Disability and Severity Improvement during Long-Term Treatment with Erenumab Eur. Neurol. (IF 2.4) Pub Date : 2022-12-20
The aim of the present study was to assess erenumab efficacy in migraine disability and intensity throughout the first treatment cycle, discontinuation, and the first 6 months of re-treatment in patients with high-frequency episodic migraine. The study design was retrospective and observational. Inclusion criteria were the following: diagnosis of high-frequency episodic migraine and ongoing treatment
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Migraine Disability and Severity Improvement during Long-Term Treatment with Erenumab. Eur. Neurol. (IF 2.4) Pub Date : 2022-12-20 Marco Bolchini,Francesca Schiano di Cola,Giulia Ceccardi,Salvatore Caratozzolo,Paolo Liberini,Renata Rao,Alessandro Padovani
The aim of the present study was to assess erenumab efficacy in migraine disability and intensity throughout the first treatment cycle, discontinuation, and the first 6 months of re-treatment in patients with high-frequency episodic migraine. The study design was retrospective and observational. Inclusion criteria were the following: diagnosis of high-frequency episodic migraine and ongoing treatment
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International Conference on Psychiatry and Neurorestoratology (ICPN2022) Eur. Neurol. (IF 2.4) Pub Date : 2022-12-14
Treating neuro and psychiatric issues is one of the key challenges of our time. Since the outbreak of the novel coronavirus pneumonia (COVID-19), two research orientations, neurological manifestations and psychiatric status of patients with COVID-19 and the impact of the COVID-19 pandemic have become emerging research hot spots in recent years. To overcome the enormous burden caused by neurological
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Can Patients with Encephalitis Lethargica Wake Up from Local Sleep? A Reply to Brigo et al. “You Are Older, although You Do Not Know That”: Time, Consciousness, and Memory in “A Kind of Alaska” by Harold Pinter (1930–2008) Eur. Neurol. (IF 2.4) Pub Date : 2022-12-14 Angela Comanducci, Alessandro Viganò, Mario Meloni
Eur Neurol
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Early Initiation of Exoskeletal Robotic Gait Training Improves Functional Outcomes in the Patients with Stroke: A Retrospective Observational Study Eur. Neurol. (IF 2.4) Pub Date : 2022-12-14 Akira Degami, Shingo Taki, Takeshi Imura, Yuji Iwamoto, Naoki Imada, Ryo Tanaka, Susumu Urakawa, Tetsuji Inagawa, Hayato Araki, Osamu Araki
Introduction: The effect of early initiation of gait training using hybrid assistive limb (HAL) remains unclear. This observational study aimed to investigate whether early initiation of gait training using HAL improves functional outcomes in patients with stroke. Methods: We retrospectively analyzed patients with acute stroke admitted to our facility. HAL was used for exoskeletal robotic gait training
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The Friar with the Crutch: A Pictorial Hint of the Stroke Suffered by Bernardino da Fossa (1420–1503) Eur. Neurol. (IF 2.4) Pub Date : 2022-12-13 Luca Ventura
Background: Works of art may serve as a source of evidence of diseases and help to better understand their natural history. Summary: Bernardino da Fossa was a 15th-century Italian Franciscan friar who wrote sermons and historical works. He described the events of the Observance Reformation movement since its dawn, but the last chapter is unexplainably interrupted. This has been considered suggestive
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Association of Dietary Patterns with Parkinson’s Disease: A Cross-Sectional Study Based on the United States National Health and Nutritional Examination Survey Database Eur. Neurol. (IF 2.4) Pub Date : 2022-12-05 Shulan Xu, Wei Li, Qing Di
Introduction: Although studies have explored some dietary patterns for Parkinson’s disease (PD), more other dietary patterns and food item under the dietary pattern are needed to investigate. This study aimed to identify more categories of dietary patterns for PD and further explore the association of single food item with PD. Methods: The 2015–2018 US National Health and Nutritional Examination Survey
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Constipation in Parkinson’s Disease: A Systematic Review and Meta-Analysis Eur. Neurol. (IF 2.4) Pub Date : 2022-12-05 Lulu Yao, Wei Liang, Jiahao Chen, Qian Wang, Xiaobo Huang
Introduction: Constipation is a common nonmotor symptom of Parkinson’s disease (PD) and has been reported to increase the risk of developing PD. However, previous studies have yielded conflicting results. Understanding this correlation may promote early diagnosis and treatment of PD, which could help patients improve their quality of life. This study aimed to investigate the association between constipation
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Influence of Cardiovascular Risk Factors in Early Relapsing-Remitting Multiple Sclerosis: A Retrospective Analysis Eur. Neurol. (IF 2.4) Pub Date : 2022-12-05 Pablo Arroyo-Pereiro, Albert Muñoz-Vendrell, Laura Bau, Elisabet Matas, Lucia Romero-Pinel, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos
Introduction: Prior studies have suggested that cardiovascular risk factors (CVRFs) can affect the prognosis of multiple sclerosis (MS). The aim of this study was to assess if CVRFs affect the early course of MS. Methods: A retrospective observational study was performed, including patients diagnosed with relapsing-remitting MS (RRMS) from 2010 to 2020, with at least 2 years of disease and 6 months
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An Association Study of ESR1–XbaI and PvuII Gene Polymorphism in Migraine Susceptibility in the Jammu Region Eur. Neurol. (IF 2.4) Pub Date : 2022-11-25 Sawan Kumar, Jyotdeep Kour Raina, Amrit Sudershan, Kanak Mahajan, Raman Jasrotia, Chinmoyee Maharana, Rakesh K. Panjalia, Parvinder Kumar
Introduction: Migraine is a neurovascular disorder and is clinically characterized by episodic attacks of mild to severe headaches. Due to the involvement of multiple environmental and genetic factors, it has become a much more complex neurological condition to understand. Apart from the environmental variables, a plethora of genes have been implicated, and one such example is ESR1. The present study
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Integrin β1 and the Repair after Nervous System Injury Eur. Neurol. (IF 2.4) Pub Date : 2022-10-25 Lei Yan, Zhiming Cui
Background: Integrin β1, as a member of the adhesion molecule family, is widely distributed in many kinds of cells and participates in multiple biological functions of the nervous system, including cytoskeleton reorganization, axon growth, and inflammatory injury. Summary: After nervous system injury, integrin β1 expressed by microglia is mainly involved in promoting inflammatory damage; integrin β1
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Effectiveness of Progressive Resistance Training in Parkinson’s Disease: A Systematic Review and Meta-Analysis Eur. Neurol. (IF 2.4) Pub Date : 2022-10-20 Xiaoxia Yang, Zhiyun Wang
Introduction: The aim of this study was to systematically explore progressive resistance training (PRT) effects in Parkinson’s disease (PD). Methods: Eligible literature was systematically searched from five electronic databases (PubMed, Web of Science, Ovid, Wanfang, and China National Knowledge Infrastructure) from their inception to February 2022. Included studies were selected based on strict eligibility