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  • CSF-Venous Fistula
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-21
    Michelle Roytman, Gayle Salama, Matthew S. Robbins, J. Levi Chazen

    Purpose of Review To provide an update on recent developments in the understanding, diagnosis, and treatment of CSF-venous fistula (CVF). Recent Finding CVF is a recently recognized cause of spontaneous intracranial hypotension (SIH), an important secondary headache, in which an aberrant connection is formed between the spinal subarachnoid space and an adjacent spinal epidural vein permitting unregulated

  • Quantitative Sensory Testing to Predict Postoperative Pain
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-14
    Matthias Braun, Corina Bello, Thomas Riva, Christian Hönemann, Dietrich Doll, Richard D. Urman, Markus M. Luedi

    Purpose of Review We review the relevance of quantitative sensory testing (QST) in light of acute and chronic postoperative pain and associated challenges. Recent Findings Predicting the occurrence of acute and chronic postoperative pain with QST can help identify patients at risk and allows proactive preventive management. Generally, central QST testing, such as temporal summation of pain (TSP) and

  • Acupuncture for the Management of Low Back Pain
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-14
    Ivan Urits, Jeffrey Kway Wang, Kristina Yancey, Mohammad Mousa, Jai Won Jung, Amnon A. Berger, Islam Mohammad Shehata, Amir Elhassan, Alan D. Kaye, Omar Viswanath

    Purpose of Review This evidence-based systematic review will focus on the use of acupuncture and its role in the treatment of low back pain to help better guide physicians in their practice. It will cover the background and the burden of low back pain and present the current options for treatment and weigh the evidence that is available to support acupuncture as a treatment modality for low back pain

  • Recent Applications of Virtual Reality for the Management of Pain in Burn and Pediatric Patients
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-14
    Samuel P. Ang, Michael Montuori, Yuriy Trimba, Nicole Maldari, Divya Patel, Qian Cece Chen

    Purpose of Review Virtual reality, via integration of immersive visual and auditory modalities, offers an innovative approach to pain management. The purpose of this review is to investigate the clinical application of virutal reality as an adjunct analgesic to standard of care, particularly in pediatric and burn patients. Recent Findings Although relatively new, virtual reality has been successfully

  • Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-14
    Kanishka Rajput, Nalini Vadivelu

    Purpose of Review With the widespread growth of ambulatory surgery centers (ASCs), the number and diversity of operations performed in the outpatient setting continue to increase. In parallel, there is an increase in the proportion of patients with a history of chronic opioid use and misuse undergoing elective surgery. Patients with such opioid tolerance present a unique challenge in the ambulatory

  • Brain Excitability in Tension-Type Headache: a Separate Entity from Migraine?
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-07
    Wei-Ta Chen, Fu-Jung Hsiao, Shuu-Jiun Wang

    Purpose of Review Tension-type headache is often regarded as the “normal” headache due to its high prevalence and mild disability in contrast with migraine. Clinically, both headaches are common comorbidities to each other. To date there has been many studies linked migraine to a brain excitability disorder. This review summarized earlier studies on brain excitability of TTH and discuss if TTH is a

  • The Impact of Parental Migraine on Children
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2021-01-06
    Maya Marzouk, Elizabeth K. Seng

    Purpose of Review This review surveys our current understanding of the impact of parental migraine on children. Understanding the impact of migraine on others in a family unit is critical to describing the full burden of migraine and to developing psychosocial supportive interventions for patients and their families. Recent Findings Having a parent with migraine is associated with several early developmental

  • Review of Ilioinguinal Nerve Blocks for Ilioinguinal Neuralgia Post Hernia Surgery
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-12-17
    Andrew K. Wong, Andrew T. Ng

    Purpose of Review The purpose of this review is to evaluate the current evidence on ultrasound-guided ilioinguinal nerve blocks for ilioinguinal neuralgia post hernia surgery. Methods A literature search was performed to find all relevant case reports, case series, prospective or retrospective cohort studies, and randomized controlled trials (RCTs) where ultrasound-guided or landmark-based ilioinguinal

  • Noninvasive Neuromodulation in Migraine
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-12-16
    Benzion Blech, Amaal J. Starling

    Purpose of Review The past two decades has seen an influx of noninvasive neuromodulation devices aimed at treatment of various primary headache disorders, including cluster headache and migraine. This narrative review is to summarize the current options in noninvasive neuromodulation in migraine. Recent Findings A variety of noninvasive neuromodulation devices have been FDA cleared and marketed for

  • Migraine in Children Under 7 Years of Age: a Review
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-12-16
    Vincenzo Raieli, Antonina D’Amico, Ettore Piro

    Purpose of review Despite the accumulation of a significant amount of data on pediatric headache, few studies have been conducted on its occurrence in children under 7 years of age. Within primary headaches in this age, migraine especially, turns out to be a disorder affecting up to 4% of the general population. An underestimate of its true prevalence can be due to lack of specific diagnostic markers

  • Latest Insights into the Pathophysiology of Migraine: the ATP-Sensitive Potassium Channels
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-12-03
    Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi, Messoud Ashina

    Purpose of Review Migraine remains a challenging condition to treat, thus highlighting the need for a better understanding of its molecular mechanisms. This review intends to unravel a new emerging target in migraine pathophysiology, the adenosine 5′-triphosphate-sensitive K+ (KATP) channel. Recent Findings KATP channel is a common denominator in the cyclic adenosine monophosphate (cAMP) and cyclic

  • Patient Satisfaction in Academic Pain Management Centers: How Do We Compare?
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-11-18
    Joseph Charles Gonnella, Alaa Abd-Elsayed, Lynn Kohan

    Purpose of Review The aim of the study was to investigate patient satisfaction amongst academic pain management centers and associated factors. Recent Findings Approximately 25% of pain management centers perform better than other practices on Press Ganey surveys. The majority of respondents (96%) indicated that pain management practices were uniquely positioned to receive poorer scores on patient

  • Interventional Procedures in Episodic Migraine
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-11-12
    Brian M. Plato, Mandy Whitt

    Purpose of Review Migraine is a common disorder which in many cases can be adequately treated with medications. However, there are some patients who may either not respond to medications or have contraindications to their use. In this review, we will evaluate the available literature on the interventional procedures available to treat patients with episodic migraine. We will review the technical details

  • Narrative Review: Headaches After Reversible Cerebral Vasoconstriction Syndrome
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-11-08
    Yu-Hsiang Ling, Shih-Pin Chen

    Purpose of Review Reversible cerebral vasoconstriction syndrome (RCVS) is a disorder with distinct features: recurrent thunderclap headaches with reversible vasoconstriction of intracranial arteries. Substantial studies regarding outcomes after RCVS were conducted, showing favorable functional outcomes in most patients despite the potentially life-threatening complications of RCVS, including ischemic

  • Exparel for Postoperative Pain Management: a Comprehensive Review
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-10-23
    Alan David Kaye, Cassandra Armstead-Williams, Farees Hyatali, Katherine S. Cox, Rachel J. Kaye, Lauren K. Eng, Muhammad A. Farooq Anwar, Perene V. Patel, Shilpa Patil, Elyse M. Cornett

    Purpose of Review Multimodal pain management is the most effective way to treat postsurgical pain. However, the use of opioids for acute pain management has unfortunately been a significant contributor to the current opioid epidemic. The use of opioids should be limited and only considered a “rescue” pain medication after other modalities of pain management have been utilized. Recent Findings It may

  • The Impact of the Quantity and Quality of Social Support on Patients with Chronic Pain
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-10-15
    Morgan McMurtry, Omar Viswanath, Michele Cernich, Natalie Strand, John Freeman, Cynthia Townsend, Alan D. Kaye, Elyse M. Cornett, Christopher Wie

    Purpose of Review Social support is an important yet often overlooked aspect of chronic pain management. Understanding the impact of social support on patients with chronic pain and determining if a relationship exists between a patient’s perceived social support and their perceived quality of life is a crucial component to completely treating a pain patient. We sought to develop an intervention for

  • Nummular Headache - a Case Report of a Rare Entity
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-10-12
    Davis C. Thomas, Gary M. Heir, Amey G. Patil, Prutha K. Soni

    Purpose of Review The purpose of this manuscript is to shed light on systematic work-up of a diagnostic challenge such as nummular headache (NH), and to summarize the relevant literature on NH. Recent Findings The specific nature of the shape of the pain site is usually characteristic of NH. Multiple modalities of investigation including succinct imaging are necessary to successfully rule out other

  • Clinical Effectiveness and Mechanism of Action of Spinal Cord Stimulation for Treating Chronic Low Back and Lower Extremity Pain: a Systematic Review
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-30
    Ricardo Vallejo, Ashim Gupta, David L. Cedeno, Alejandro Vallejo, William J. Smith, Samuel M. Thomas, Ramsin Benyamin, Alan D. Kaye, Laxmaiah Manchikanti

    Purpose of Review The purpose of the present systematic review is to provide a current understanding of the mechanism of action and the evidence available to support clinical decision-making. The focus is to summarize randomized controlled trials (RCTs) and nonrandomized or observational studies of spinal cord stimulation in chronic pain to understand clinical effectiveness and the mechanism of action

  • Chronic Cluster Headache Update and East–West Comparisons: Focusing on Clinical Features, Pathophysiology, and Management
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-29
    Chia-Lin Tsai, Guan-Yu Lin, Sheng-Kai Wu, Fu-Chi Yang, Shuu-Jiun Wang

    Purpose of Review This review provides an update on chronic cluster headache (CH) focusing on clinical features, pathophysiology, and management as well as comparisons between Eastern and Western populations. Recent Findings Chronic CH in Eastern populations was relatively rare, compared to that in Western populations. Lacrimation and/or conjunctival injection is the most frequently reported cranial

  • Complications Associated with Lumbar Transforaminal Epidural Steroid Injections
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-29
    Andrew Chang, Andrew T. Ng

    Purpose of Review Low back pain with radicular symptoms is a common cause of disability in the adult population in the USA. Lumbar transforaminal epidural steroid injection (TFESI) is one of the most frequently used intervention for lumbar radiculitis. The purpose of this review is to evaluate complications associated with lumbar TFESI. Recent Findings Based on the literature review, the reported rate

  • Brain Metabolism and Structure in Chronic Migraine
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-29
    Kuan-Lin Lai, David M. Niddam

    Purpose of Review The purpose of this paper is to review and synthesize current literature in which neurochemical and structural brain imaging were used to investigate chronic migraine (CM) pathophysiology and to further discuss the clinical implications. Recent Findings Spectroscopic and structural MRI studies have shown the presence of both impaired metabolism and structural alterations in the brain

  • Efficacy and Feasibility of Behavioral Treatments for Migraine, Headache, and Pain in the Acute Care Setting
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-26
    Daniel Vekhter, Matthew S. Robbins, Mia Minen, Dawn C. Buse

    Purpose of Review This narrative review examines the use of behavioral interventions for acute treatment of headache and pain in the emergency department (ED)/urgent care (UC) and inpatient settings. Recent Findings Behavioral interventions demonstrate reductions of pain and associated disability in headache, migraine, and other conditions in the outpatient setting. Behavioral treatments may be a useful

  • Post Traumatic Headache: Clinical care of athletes vs non athletes with Persistent Post Traumatic Headache after Concussion: Sports Neurologist and Headache Specialist Perspective.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-09-03
    F X Conidi

    PurposeThe purpose of this paper is to review and outline the similarities and differences in the treatment of athletes compared with that of other populations with a persistent post-traumatic headache after a concussion. Recent FindingsAfter an extensive review of the literature and despite well over 2 million Americans experiencing post-traumatic headache (PTH) each year, a number of which will continue

  • Complications of Fluoroscopically Guided Cervical Interlaminar Epidural Steroid Injections.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-26
    Andrew Chang,Dajie Wang

    Purpose of ReviewCervical interlaminar epidural steroid injection is a common intervention in the management of cervical radiculitis. Given the large number of injections done annually, it is important to assess the potential complications associated with this procedure. Recent FindingsBased on current published studies, the overall complication rate varies. The vast majority are minor complications

  • Low-Dose Naltrexone for Chronic Pain: Update and Systemic Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-26
    Phillip S Kim,Michael A Fishman

    Purpose of ReviewThe purpose of this review is to evaluate and explain our current understanding of the clinical use of low-dose naltrexone in the treatment of chronic pain. Recent FindingsRecent pre-clinical uses and clinical studies further elucidate the use of low-dose naltrexone in the treatment of chronic pain. SummaryLow-dose naltrexone (LDN) has shown promise to reduce symptoms related to chronic

  • Epidemiology of Headache in Children and Adolescents-Another Type of Pandemia.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-25
    Vera Nieswand,Matthias Richter,Gudrun Gossrau

    Purpose of ReviewHeadaches are not only responsible for restrictions in everyday life in adults. In children and adolescents, regular headaches lead also to reduced life quality and limitations in the social sphere, in school education, and in professional careers. Here, we provide an overview on the frequency of headache in children and adolescents with the aim of increasing awareness about this particular

  • Pain Syndromes Secondary to Cluneal Nerve Entrapment.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-21
    Jay Karri,Mani Singh,Vwaire Orhurhu,Mihir Joshi,Alaa Abd-Elsayed

    Purpose of ReviewThe purpose of this review is to provide an overview of the cluneal nerves, present a summary of pain syndromes secondary to clunealgia, and evaluate current literature for diagnostic and treatment modalities. Recent FindingsMultiple trials and studies have reported success with numerous modalities ranging from nerve blocks, neuroablation, and even peripheral neuromodulation with varying

  • Ultrasound-Guided Neuraxial Anesthesia.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-18
    Jinlei Li,Ramya Krishna,Yang Zhang,David Lam,Nalini Vadivelu

    Purpose of ReviewThere has been a recent surge of interest in clinical applications of ultrasound, which has revolutionized acute pain management. This review is to summarize the current status of ultrasound utilization in neuraxial anesthesia, the most common type of regional anesthesia. Recent FindingsUltrasound-assisted and ultrasound-guided neuraxial anesthesia has improved clinical accuracy and

  • Surgical Flow Disruptions, a Pilot Survey with Significant Clinical Outcome Implications.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-18
    David Silver,Alan D Kaye,Douglas Slakey

    Purpose of ReviewSurgical flow disruptions (SFD) are deviations from the progression of a procedure which can be potentially compromising to the safety of the patient. Investigators have previously demonstrated that SFDs can increase the likelihood of error. To date, there has been no investigation into flow disruptions through the eyes of clinicians in the operating room. This study, therefore, attempted

  • Neurosurgical Evaluation for Patients with Chronic Lower Back Pain.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-17
    Daniel Franco,Aria Mahtabfar,Kevin Hines,Victor Sabourin,Anthony Stefanelli,James Harrop

    Purpose of ReviewChronic low back pain (CLBP) is a major cause of disability in the USA, and it affects approximately 1 in 4 Americans. CLBP patients are commonly referred to or seek out neurosurgical evaluations and opinions for treatment and management. Recent FindingsLiterature shows that only a minority of patients with CLBP may benefit from a surgical procedure. These patients that present to

  • Neurophysiological Mechanisms Supporting Mindfulness Meditation-Based Pain Relief: an Updated Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-17
    Alex Jinich-Diamant,Eric Garland,Jennifer Baumgartner,Nailea Gonzalez,Gabriel Riegner,Julia Birenbaum,Laura Case,Fadel Zeidan

    Purpose of ReviewThis review examines recent (2016 onwards) neuroscientific findings on the mechanisms supporting mindfulness-associated pain relief. To date, its clear that mindfulness lowers pain by engaging brain processes that are distinct from placebo and vary across meditative training level. Due to rapid developments in the field of contemplative neuroscience, an update review on the neuroimaging

  • An Update on Idiopathic Hypertrophic Cranial Pachymeningitis for the Headache Practitioner.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-17
    Larry Charleston,Wade Cooper

    Purpose of ReviewWe aim to review idiopathic hypertrophic cranial pachymeninigitis (IHCP), describe common head pain patterns and features associated with the disorder, suggest potential classification of head pain syndromes based on the recently published International Classification of Headache Disorders-3, explore pathophysiology found to be associated with cases of IHCP, and indicate common treatment

  • Current Concepts of Minimally Invasive Treatment Options for Plantar Fasciitis: a Comprehensive Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-12
    Morgan Hasegawa,Ivan Urits,Vwaire Orhurhu,Mariam Salisu Orhurhu,Joseph Brinkman,Stephen Giacomazzi,Lukas Foster,Laxmaiah Manchikanti,Alan D Kaye,Rachel J Kaye,Omar Viswanath

    Purpose of ReviewChronic foot pain constitutes a large portion of the chronic pain burden in the overall population. Plantar fasciitis is one of the most common and most easily identifiable causes of chronic foot pain. The syndrome has been estimated to cause 11 to 15% of foot pain visits, requiring professional care. Moreover, studies have suggested that 1 in 10 people will develop plantar fasciitis

  • Correction to: Intravenous Migraine Treatment in Children and Adolescents.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-11
    Klaus G Werner,Sharoon Qaiser,Marielle A Kabbouche,Beverly Murphy,Ian Maconochie,Andrew D Hershe

    The original publication of this article unfortunately contained the incorrect version of the manuscript. The original article has been corrected.

  • Novel Agents in Neuropathic Pain, the Role of Capsaicin: Pharmacology, Efficacy, Side Effects, Different Preparations.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-08-06
    O Morgan Hall,Alaina Broussard,Tierra Range,Michelle A Carroll Turpin,Savannah Ellis,Victoria M Lim,Elyse M Cornett,Alan David Kaye

    Purpose of ReviewCapsaicin is a natural substance used to treat neuropathic pain because of its ability to be used in a more direct form on patients and efficiently treat their pain without the amount of side effects seen in the use of oral medications. Recent FindingsCurrently, the treatments for neuropathic pain are, control of the underlying disease process, then focused on symptomatic relief with

  • Neuropathic Pain and Sickle Cell Disease: a Review of Pharmacologic Management.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-24
    Mariam Salisu Orhurhu,Robert Chu,Lauren Claus,Jacob Roberts,Bisi Salisu,Ivan Urits,Ejovwoke Orhurhu,Omar Viswanath,Alan D Kaye,Aaron J Kaye,Vwaire Orhurhu

    Purpose of ReviewSickle cell disease (SCD) remains among the most common and severe monogenic disorders present in the world today. Although sickle cell pain has been traditionally characterized as nociceptive, a significant portion of sickle cell patients has reported neuropathic pain symptoms. Our review article will discuss clinical aspects of SCD-related neuropathic pain, epidemiology of neuropathic

  • Unusual Brain MRI Findings in Patients Imaged for Headache: a Case Series.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-20
    Yadira Flores-Montanez,Stephanie J Nahas

    Purpose of ReviewWe describe a series of cases with unusual brain MRI findings in patients who present with headache disorders. Recent FindingsIncidental findings in patients imaged for headache include the following: aneurysm, arachnoid cyst, cerebral vascular malformations, Arnold-Chiari malformations, empty sella turcica, gray matter heterotopias, mastoiditis, mega cisterna magna, meningioma, normal

  • Cephalgia Alopecia.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-15
    Kate O Bedrin,Carrie Dougherty

    Purpose of ReviewIn this review, we examine reported cases of cephalgia alopecia including the initial case report from 2006. The goal is to review the clinical description, pathophysiology, diagnosis, and treatment of cephalgia alopecia. Recent FindingsThe pathophysiology of the headache and hair loss in cephalgia alopecia is believed to be related to neuroregulation of skin and nerve. It is hypothesized

  • Headache in Behçet's Disease.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-15
    Marianna Vinokur,John Glenn Burkett

    Purpose of ReviewOur objective is to describe the various neurologic manifestations of Behcet’s syndrome with special attention to headache syndromes. Recent FindingsMost recent studies have focused on data collection to better characterize the relatively rare disorder of neuro-Behcets (NBD). In patients with Behcet’s disease (BD) who are experiencing headache, most are primary headache disorders,

  • Pediatric Migraine Phenomena and Variants: Don't Let Them Go Over Your Head.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-15
    Shanna Swartwood,Kendra Pham,Meghan S Candee

    Purpose of ReviewPrimary care providers, general pediatric neurologists, and other related subspecialty providers require a clear understanding of pediatric migraine with typical aura and its variants. Recent FindingsWe highlight some of the genetic mutations known to contribute to specific types of migraine with aura, discuss the ophthalmologic phenomena of migraine and call attention to some of the

  • Endometriosis Pain Management: a Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-15
    Daniel Carlyle,Tarek Khader,David Lam,Nalini Vadivelu,Devina Shiwlochan,Cho Yonghee

    Purpose of ReviewThe purpose of this review is to summarize the up-to-date pain management options and recommendations for the challenging disease, endometriosis. Recent FindingsThe mainstays of endometriosis advances of both surgical and medical management continue to evolve. Experimental pharmaceuticals include Gestirone, and aromatase inhibitors have shown promise but are still under scrutiny. Surgical

  • Diagnosis, Treatment, and Management of Dejerine-Roussy Syndrome: a Comprehensive Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-15
    Ivan Urits,Kyle Gress,Karina Charipova,Vwaire Orhurhu,John A Freeman,Rachel J Kaye,Alan D Kaye,Elyse Cornett,Paul J Delahoussaye,Omar Viswanath

    Purpose of ReviewPost-stroke pain represents a complex condition with few standardized diagnostic criteria. As such, the array of symptoms is often difficult to categorize and diagnose. Central post-stroke pain (CPSP), also known as Dejerine–Roussy syndrome, presents as painful paresthesia in any part of the body that is usually coupled with sensory abnormalities. Recent FindingsIn patients who had

  • Intravenous Migraine Treatment in Children and Adolescents.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-07-08
    Klaus Werner,Sharoon Qaiser,Marielle Kabbouche,Beverly Murphy,Ian Maconochie,Andrew D Hershey

    Purpose of ReviewMost treatment algorithms and guidelines for acute intravenous (IV) treatments of migraine for children and adolescents are derived from adult studies and often based on clinician’s personal experience regarding what is known to work. An overview of the current level of evidence of different acute IV treatments for migraine and status migrainosus in children and adolescents may help

  • A Comprehensive Review of the Treatment and Management of Myofascial Pain Syndrome.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-27
    Annemarie Galasso,Ivan Urits,Daniel An,Diep Nguyen,Matthew Borchart,Cyrus Yazdi,Laxmaiah Manchikanti,Rachel J Kaye,Alan D Kaye,Ken F Mancuso,Omar Viswanath

    Purpose of ReviewMyofascial pain syndrome (MPS) is a musculoskeletal pain condition that stems from localized, taut regions of skeletal muscle and fascia, termed trigger points. The purpose of this comprehensive review is to provide updated information on prevalence, pathophysiology, and treatment modalities with a focus on interventional modalities in managing MPS. Recent FindingsThough MPS can present

  • Utilizing the Biopsychosocial Model in Concussion Treatment: Post-Traumatic Headache and beyond.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-27
    Johna K Register-Mihalik,J D DeFreese,Christine E Callahan,Kevin Carneiro

    Purpose of ReviewTo discuss recent literature concerning the application of the biopsychosocial model in the management of concussion and post-concussion headache. Recent FindingsCurrent research suggests that the biopsychosocial model is applicable to the concussion management process, particularly management of post-concussion headache. Such application is best illustrated by current active treatment

  • A Comprehensive Review of the Celiac Plexus Block for the Management of Chronic Abdominal Pain.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-11
    Ivan Urits,Mark R Jones,Vwaire Orhurhu,Jacquelin Peck,Devin Corrigan,Ashley Hubble,Megan Andrews,Ruby Feng,Laxmaiah Manchikanti,Alan D Kaye,Rachel J Kaye,Omar Viswanath

    Purpose of ReviewChronic abdominal pain (CAP) is a significant health problem that can dramatically affect quality of life and survival. Pancreatic cancer is recognized as one of the most painful malignancies with 70–80% suffering from substantial pain, often unresponsive to typical medical management. Celiac plexus neurolysis and celiac plexus block (CPB) can be performed to mitigate pain through

  • Pediatric Migraine and Academics.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-11
    Raquel Langdon,Marc DiSabella,Jeffrey Strelzik,Angela Fletcher

    Purpose of ReviewThe purpose of this review is to examine the multitude of factors which may impact learning and academic performance in patients with pediatric migraine. Recent FindingsA range of associations of varying degree were noted between pediatric migraine and conditions such as ADHD, learning disabilities, sleep disorders, and psychiatric comorbidities with regard to headache pain and school

  • A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-11
    Alexander Capuco,Ivan Urits,Vwaire Orhurhu,Rebecca Chun,Bhavesh Shukla,Megan Burke,Rachel J Kaye,Andrew J Garcia,Alan D Kaye,Omar Viswanath

    Purpose of ReviewPostmastectomy pain syndrome (PMPS) remains poorly defined, although it is applied to chronic neuropathic pain following surgical procedures of the breast, including mastectomy and lumpectomy in breast-conserving surgery. It is characterized by persistent pain affecting the anterior thorax, axilla, and/or medial upper arm following mastectomy or lumpectomy. Though the onset of pain

  • Exercise and Migraine Prevention: a Review of the Literature.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-11
    Mark Barber,Anna Pace

    Purpose of ReviewThis review intends to characterize the recent literature pertaining to the role of aerobic exercise in the prevention of migraine. Areas of consensus within that literature may be used to guide clinical practice, allowing for the promulgation of evidence-based practice recommendations. Recent FindingsThe past decade has seen the publication of numerous high-quality studies that explore

  • Considerations and Implications of Cannabidiol Use During Pregnancy.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-10
    Syena Sarrafpour,Ivan Urits,Jordan Powell,Diep Nguyen,Jessica Callan,Vwaire Orhurhu,Thomas Simopoulos,Omar Viswanath,Alan D Kaye,Rachel J Kaye,Elyse M Cornett,Cyrus Yazdi

    Purpose of ReviewCannabis is a naturally occurring plant that is composed of over sixty phytocannabinoids, of which cannabidiol (CBD) has been recently identified as having therapeutic potential. Recent FindingsAlthough not clearly understood in its mechanism of action, CBD contains potent anti-inflammatory, anti-hyperalgesia, and analgesic qualities now being further analyzed for its use in the treatment

  • The Role of the Cannabinoid System in Pain Control: Basic and Clinical Implications.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-06
    John Wolf,Ivan Urits,Vwaire Orhurhu,Jacquelin Peck,Mariam Salisu Orhurhu,Stephen Giacomazzi,Daniel Smoots,Charlie Piermarini,Laxmaiah Manchikanti,Alan D Kaye,Rachel J Kaye,Omar Viswanath

    Purpose of ReviewThe purpose of this review is to provide a comprehensive update of the different known components of the endogenous cannabinoid system and the mechanisms of action, as it applies to analgesia. Recent FindingsFollowing the discovery of the endogenous cannabinoid system in the early 1990s and the subsequent characterization of the cannabinoid receptor, there has been a renewed interest

  • Gut Microbiome Dysbiosis and Depression: a Comprehensive Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-06
    Alexander Capuco,Ivan Urits,Jamal Hasoon,Rebecca Chun,Brittany Gerald,Jason K Wang,Anh L Ngo,Thomas Simopoulos,Alan D Kaye,Matthew M Colontonio,Tomasina Q Parker-Actlis,Mitchell C Fuller,Omar Viswanath

    Purpose of ReviewThe human gut microbiome is involved in a bi-directional communication pathway with the central nervous system (CNS), termed the microbiota–gut–brain axis. The microbiota–gut–brain axis is believed to mediate or modulate various central processes through the vagus nerve. The microbiota–gut–brain axis is involved with the production of microbial metabolites and immune mediators which

  • Minimally Invasive Therapies for Osteoarthritic Hip Pain: a Comprehensive Review.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-06-06
    Ivan Urits,Vwaire Orhurhu,Jordan Powell,Anu Murthy,Brendon Kiely,Samara Shipon,Rachel J Kaye,Alan D Kaye,Brett L Arron,Elyse M Cornett,Omar Viswanath

    Purpose of ReviewOsteoarthritis (OA) is a highly prevalent cause of chronic hip pain, affecting 27% of adults aged over 45 years and 42% of adults aged over 75 years. Though OA has traditionally been described as a disorder of “wear-and-tear,” recent studies have expanded on this understanding to include a possible inflammatory etiology as well, damage to articular cartilage produces debris in the

  • Headache in Ruptured Intracranial Dermoid Cysts.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-29
    Amir Soheil Tolebeyan,Deena E Kuruvilla

    Purpose of ReviewIntracranial dermoid cysts are benign, rare mass-occupying lesions of the central nervous system arising from the neuroectodermal cell lines. While rupture of intracranial dermoid cysts is rare, it can present with a variety of clinical manifestations. To explore the headache manifestations among patients with ruptured intracranial dermoid cysts. To our knowledge, limited studies focusing

  • Headache in the Older Population: Causes, Diagnoses, and Treatments.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-29
    Jennifer Robblee,Rashmi Halker Singh

    Purpose of ReviewPrimary headaches are less common and differ in presentation in older versus younger individuals. Secondary headaches become more common among older patients. Recent FindingsDiagnosis and management of headaches in those > 65 years are discussed. Migraine and tension-type headaches are rarely new onset in this age group and should be a diagnosis of exclusion. In older individuals,

  • Acupuncture for Migraine: a Review of the Data and Clinical Insights.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-29
    Lauren R Natbony,Niushen Zhang

    Purpose of ReviewThe purpose of this review is to discuss the current evidence for acupuncture in migraine and to provide insight into which patients may benefit most from acupuncture. Recent FindingsMultiple studies support acupuncture as a validated modality for the prevention of episodic migraine. While small studies on acupuncture for the prevention of chronic migraine are encouraging, evidence

  • Fear, Avoidance, and Disability in Headache Disorders.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-29
    Daniel G Rogers,Tracy A Protti,Todd A Smitherman

    Purpose of ReviewThe purpose of this review is to summarize the role of avoidance behavior in headache-related disability and overview relevant clinical implications. Recent FindingsAvoidance occupies a central role in contemporary psychological perspectives on headache disorders and other chronic pain conditions. Several cognitive constructs of relevance to headache are influenced and maintained by

  • Is Percutaneous Adhesiolysis Effective in Managing Chronic Low Back and Lower Extremity Pain in Post-surgery Syndrome: a Systematic Review and Meta-analysis.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-28
    Laxmaiah Manchikanti,Nebojsa Nick Knezevic,Satya P Sanapati,Mahendra R Sanapati,Alan D Kaye,Joshua A Hirsch

    Purpose of ReviewThe growing prevalence of spinal pain in the USA continues to produce substantial economic impact and strain on health-related quality of life. Percutaneous adhesiolysis is utilized for recalcitrant, resistant conditions involving spinal pain when epidural injections have failed to provide adequate improvement, especially low back and lower extremity pain, specifically in post-lumbar

  • The ALblation Technique for Treating Migraine Headache.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-13
    Alaa Abd-Elsayed

    PurposeThis work aims at describing a technique “The ALblation technique” for treating migraine headache. This technique describes radiofrequency ablation for supraorbital, supratrochlear, lesser occipital and greater occipital nerves bilaterally for treating migraine headache. This is a novel procedure that was not described before. Recent findingsAuthor published some articles on radiofrequency ablation

  • Recommendations for Managing Opioid-Tolerant Surgical Patients within Enhanced Recovery Pathways.
    Curr. Pain Headache Rep. (IF 2.985) Pub Date : 2020-05-08
    Alexander Stone,Antonia Roberts,Hans D de Boer,Alan D Kaye,William J Fawcett,Richard D Urman

    Purpose of ReviewOne of the consequences of the opioid epidemic is an increase in the number of opioid-tolerant patients. These patients are at higher risk for readmission and longer hospital stays following surgery. Enhanced recovery after surgery (ERAS) pathways can be used as a framework for providing high-quality comprehensive care to patient population. It is estimated that as many as 15% of all

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