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Vertebral plate and ligament composite laminoplasty in spinal cord tumor surgery: Analysis of 94 patients Trans. Neurosci. (IF 1.373) Pub Date : 2021-01-20 Xu Hao; Wang Lin
The aim of this study was to evaluate the value and long-term effect of laminectomy or laminoplasty in spinal cord tumor surgery.
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The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme Trans. Neurosci. (IF 1.373) Pub Date : 2021-01-20 Bangming Guo; Wenjuan Liao; Shusheng Wang
Glioblastoma multiforme (GBM) is the leading cause of death among adult brain cancer patients. Glutathione peroxidase 2 (GPX2), as a factor in oxidative stress, plays an important role in carcinogenesis. However, its role in GBM has not been well established. The study aimed to investigate the clinical significance of GPX2 with GBM prognosis.
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Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway Trans. Neurosci. (IF 1.373) Pub Date : 2021-01-12 Kong Fu; Miancong Chen; Hua Zheng; Chuanzi Li; Fan Yang; Qian Niu
Morbidity and mortality remain high for ischemic stroke victims, and at present these patients lack effective neuroprotective agents, which improve the cure rate. In recent years, studies have shown that pelargonidin has many biological actions. However, few studies are available regarding the pelargonidin treatment of cerebral ischemia.
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IKBIP is a novel EMT-related biomarker and predicts poor survival in glioma Trans. Neurosci. (IF 1.373) Pub Date : 2021-01-08 Ying Yang; Jin Wang; Shihai Xu; Wen Lv; Fei Shi; Aijun Shan
In cancer, kappa B-interacting protein (IKBIP) has rarely been reported. This study aimed at investigating its expression pattern and biological function in brain glioma at the transcriptional level.
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Ulinastatin alleviates traumatic brain injury by reducing endothelin-1 Trans. Neurosci. (IF 1.373) Pub Date : 2020-12-28 Ting Liu; Xing-Zhi Liao; Mai-Tao Zhou
Brain edema is one of the major causes of fatality and disability associated with injury and neurosurgical procedures. The goal of this study was to evaluate the effect of ulinastatin (UTI), a protease inhibitor, on astrocytes in a rat model of traumatic brain injury (TBI).
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Tongxinluo promotes axonal plasticity and functional recovery after stroke Trans. Neurosci. (IF 1.373) Pub Date : 2020-11-25 Xiaoting Wang; Xiaoqin Huang; Mengqi Yang; Xueying Pan; Meiyi Duan; Hui Cai; Guimiao Jiang; Xianlong Wen; Donghua Zou; Li Chen
The aim of this study was to investigate the neural plasticity in contralesional cortex and the effects of tongxinluo (TXL) in cerebral ischemic rats.
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Role of prefrontal cortex during Sudoku task: fNIRS study Trans. Neurosci. (IF 1.373) Pub Date : 2020-11-03 Patil Ashlesh; Kishore K. Deepak; Kochhar Kanwal Preet
Sudoku is a popular cognitively stimulating leisure-time activity. Many studies have been directed toward finding an algorithm to solve Sudoku, but the investigation of the neural substrates involved in Sudoku has been challenging.
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Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model Trans. Neurosci. (IF 1.373) Pub Date : 2020-11-03 Nan Song; Jun Du; Yan Gao; Shenglian Yang
Deep brain stimulation (DBS) applied to the nucleus accumbens (NAc) alleviates the depressive symptoms of major depressive disorders. We investigated the mechanism of this effect by assessing gene expression and RNA methylation changes in the ventral tegmental area (VTA) following NAc-DBS in a chronic unpredictable mild stress (CUMS) mouse model of depression. Gene expression and N6-methyladenosine
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EGCG treats ICH via up-regulating miR-137-3p and inhibiting Parthanatos Trans. Neurosci. (IF 1.373) Pub Date : 2020-10-08 Jianjun Wang; Xuejun Kuang; Zhao Peng; Conghui Li; Chengwu Guo; Xi Fu; Junhong Wu; Yang Luo; Xiaolin Rao; Xiangjuan Zhou; Bin Huang; Weijun Tang; Yinjuan Tang
Intracranial hemorrhage (ICH) causes high mortality and disability without effective treatment in the clinical setting. (−)-Epigallocatechin-3-gallate (EGCG) exerts an essential role in the central nervous system and offers a promising therapeutic agent for the treatment of oxidative damage-related diseases. MiR-137 can inhibit the oxidative stress and apoptosis to attenuate neuronal injury. However
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Isovitexin modulates autophagy in Alzheimer’s disease via miR-107 signalling Trans. Neurosci. (IF 1.373) Pub Date : 2020-10-20 Jiang Cheng; Guowei Wang; Na Zhang; Fang Li; Lina Shi; Haining Li
Alzheimer’s disease (AD) is an ultimately fatal, degenerative brain disease in the elderly people. In the current work, we assessed the defensive capability of isovitexin (IVX) through an intracerebroventricular injection of streptozotocin (STZ)-induced AD mouse model.
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Modified hemispherectomy for infantile hemiparesis and epilepsy Trans. Neurosci. (IF 1.373) Pub Date : 2020-10-20 Yu-Hui Li; Dong-Sheng Li; Mei-Qing Wang; Kai Zhao; Bu-Lang Gao
To investigate the effect and medical imaging of modified hemispherectomy on patients with infantile hemiparesis and medically refractory epilepsy.
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The effect of rTMS in the management of pain associated with CRPS Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-28 Min Cheol Chang; Sang Gyu Kwak; Donghwi Park
Therapeutic management of pain in patients with complex regional pain syndrome (CRPS) is challenging. Repetitive transcranial magnetic stimulation (rTMS) has analgesic effects on several types of pain. However, its effect on CRPS has not been elucidated clearly. Therefore, we conducted a meta-analysis of the available clinical studies on rTMS treatment in patients with CRPS.
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Video-based education improves the image quality of diagnostic percutaneous cerebral angiography among elderly patients Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-28 Wenbing Wang; Yongshun Wu; Jianpeng Yuan; Qian Yang; Zhiming Zhou
Digital subtraction angiography (DSA) is considered the gold standard for cerebral vasculature observation and is increasingly applied among the elderly population. The aim of this study is to determine whether the use of a video-based education system can improve the image quality of percutaneous cerebral angiography.
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Time-restricted feeding alters isoflurane-induced memory deficits Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-21 Jia Song; Shuaishuai Chu; Xin Fang; Fangxia Xu; Peng Zhang; Xin Zhao; Zhengliang Ma; Tianjiao Xia; Xiaoping Gu
Food consumption during the rest phase promotes circadian desynchrony, which is corrected with harmful physiological and mental disorders. Previously, we found that circadian desynchrony was involved in isoflurane-induced cognitive impairment. Here, we scheduled food access to modulate daily rhythm to examine its impact on isoflurane-induced cognitive impairments. Mice were randomly transferred to
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Injury of the optic radiation in patients with mild TBI: A DTT study Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-21 Sung Ho Jang; Seong Ho Kim; You Sung Seo
We investigated injuries of the optic radiations (ORs) in patients with mild traumatic brain injury (TBI) by using diffusion tensor tractography (DTT).
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Retraction of: Identification of biological markers for better characterization of older subjects with physical frailty and sarcopenia Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-11 Bertrand Fougère; Bruno Vellas; Gabor Abellan van Kan; Matteo Cesari
Journal Name: Translational Neuroscience Volume: 11 Issue: 1 Pages: 334-334
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Prediction of muscle loss after stroke by analysis of corticospinal tract Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Ah Young Lee; Kyu Tae Choi; Min Cheol Chang
Skeletal muscle loss induces a poor rehabilitation outcome after stroke. Little is known about the usefulness of diffusion tensor tractography (DTT) findings of the corticospinal tract (CST) in terms of predicting muscle loss in affected limbs after stroke.
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BDMC protects AD in vitro via AMPK and SIRT1 Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Chenlin Xu; Zijian Xiao; Heng Wu; Guijuan Zhou; Duanqun He; Yunqian Chang; Yihui Li; Gang Wang; Ming Xie
Alzheimer’s disease (AD) is a common neurodegenerative disorder without any satisfactory therapeutic approaches. AD is mainly characterized by the deposition of β-amyloid protein (Aβ) and extensive neuronal cell death. Curcumin, with anti-oxidative stress (OS) and cell apoptosis properties, plays essential roles in AD. However, whether bisdemethoxycurcumin (BDMC), a derivative of curcumin, can exert
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Artesunate attenuates traumatic brain injury-induced impairments in rats Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Zhike Zhou; Jun Hou; Qinghua Li
Blood–brain barrier (BBB) dysfunction and neuroinflammation induced by traumatic brain injuries (TBIs) cause a succession of secondary brain damage events and finally lead to a massive and progressive cerebral neuronal destruction. Artesunate, a semisynthetic artemisinin derivative, is a potential candidate for the management of cerebral damage induced by TBI due to its protective function to BBB and
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Interleukin-27 levels in patients with myasthenia gravis Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Xiao-Jiao Liu; Lin-Jie Zhang; Ming Yi; Li-Min Li; Jing Wang; Yuan Qi; Peng Zhao; Da-Qi Zhang; Li Yang
Interleukin-27 (IL-27), which belongs to IL-12 family, influences the function of T cells (Tregs) through regulating the expression, and function of forkhead box P3 (FoxP3). In this study, we detected the IL-27 serum levels in 59 myasthenia gravis (MG) patients and 35 healthy controls (HCs). Among them, 32 MG patients received immunoglobulin intravenous (IVIG) injections (0.4 g/kg per day for 5 consecutive
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Chronic neurological diseases and COVID-19: Associations and considerations Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Shakila Meshkat; Amir Salimi; Asef Joshaghanian; Sogol Sedighi; Saman Sedighi; Vajiheh Aghamollaii
The 2019 novel coronavirus pandemic, severe acute respiratory syndrome CoV-2 (COVID-19), has been a worldwide urgent public health threat, resulting in six-hundred seventy thousand deaths to date. The COVID-19 pandemic has led to a series of public health challenges. One such challenge is the management of diseases such as chronic neurological diseases during an epidemic event. COVID-19 affects all
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IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice Trans. Neurosci. (IF 1.373) Pub Date : 2020-09-09 Lina Guo; Yang Zhang; Jinping Wang; Yingying Qi; Zongwang Zhang
Interferon regulatory factor 8 (IRF8) is involved in the pathogenesis of neuropathic pain. However, whether and how IRF8 can regulate the nicotine withdrawal (NTW)-induced hyperalgesia has not been clarified.
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Diabetes does not affect motor recovery after intracerebral hemorrhage Trans. Neurosci. (IF 1.373) Pub Date : 2020-08-25 Seung Hwa Jang; Sang Gyu Kwak; Min Cheol Chang
This retrospective study evaluated whether diabetes affects motor outcome after stroke by analyzing the effects of diabetes on motor prognosis by controlling for critical factors, including lesion type and location, corticospinal tract (CST) state, patient age, lesion volume, and treatment method during the stroke.
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Correlation between calcium, water contents and ultrasonographic appearance of atherosclerotic lesions of carotid artery lesions Trans. Neurosci. (IF 1.373) Pub Date : 2020-08-24 Béla Fülesdi; Szabolcs Farkas; Zoltán Gyöngyösi; Péter Siró; Dániel Bereczki; József Bacsó; László Csiba
We tested the hypothesis whether there is a correlation between the echogenicity and calcium and water contents of carotid plaques.
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Impaired consciousness due to injury of the ascending reticular activating system in a patient with bilateral pontine infarction: A case report Trans. Neurosci. (IF 1.373) Pub Date : 2020-08-24 Soyoung Kwak; Min Cheol Chang
The ascending reticular activating system (ARAS) is known to play an essential role in maintaining arousal and consciousness. In this report, we describe the case of a patient with impaired consciousness due to injury of the ARAS after bilateral pontine infarction. A 73-year-old female patient presented with anterior chest pain to the Emergency Department of our university hospital. She was diagnosed
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Partial enzyme digestion facilitates regeneration of crushed nerve in rat Trans. Neurosci. (IF 1.373) Pub Date : 2020-08-17 Fon-Yih Tsuang; Ming-Hong Chen; Feng-Huei Lin; Ming-Chia Yang; Chun-Jen Liao; Wen-Hsiang Chang; Jui-Sheng Sun
Peripheral nerve injury is a life-changing disability with significant socioeconomic consequences. In this rat model, we propose that partial enzyme digestion can facilitate the functional recovery of a crushed nerve. The sciatic nerves were harvested and in vitro cultured with the addition of Liberase to determine the appropriate enzyme amount in the hyaluronic acid (HA) membrane. Then, the sciatic
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Safety profile of the transcription factor EB (TFEB)-based gene therapy through intracranial injection in mice Trans. Neurosci. (IF 1.373) Pub Date : 2020-07-15 Zhenyu Li; Guangqian Ding; Yudi Wang; Zelong Zheng; Jianping Lv
Transcription factor EB (TFEB)-based gene therapy is a promising therapeutic strategy in treating neurodegenerative diseases by promoting autophagy/lysosome-mediated degradation and clearance of misfolded proteins that contribute to the pathogenesis of these diseases. However, recent findings have shown that TFEB has proinflammatory properties, raising the safety concerns about its clinical application
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Deviant cortical sulcation related to schizophrenia and cognitive deficits in the second trimester Trans. Neurosci. (IF 1.373) Pub Date : 2020-07-15 Michael Lloyd MacKinley; Priyadharshini Sabesan; Lena Palaniyappan
Aberrant cortical development, inferred from cortical folding, is linked to the risk of schizophrenia. Cortical folds develop in a time-locked fashion during fetal growth. We leveraged this temporal specificity of sulcation to investigate the timing of the prenatal insult linked to schizophrenia and the cognitive impairment seen in this illness.
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Saikosaponin A attenuates neural injury caused by ischemia/reperfusion Trans. Neurosci. (IF 1.373) Pub Date : 2020-07-02 Xinying Wang; Guofeng Yang
Inflammation is involved in cerebral ischemia/reperfusion (I/R)-induced neurological damage. Saikosaponin A (SSa), extracted from Radix bupleuri, has been reported to exert anti-inflammatory effects. This article aimed to investigate whether SSa could ameliorate neuroinflammation mediated by ischemic stroke and the underlying mechanism.
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Protective role of maize purple plant pigment against oxidative stress in fluorosis rat brain Trans. Neurosci. (IF 1.373) Pub Date : 2020-04-21 Boyan Li; Keyana Nozzari Varkani; Lu Sun; Bo Zhou; Xiaohong Wang; Lianying Guo; Han Zhang; Zhuo Zhang
In fluorosis-endemic areas, exposure to high levels of fluoride causes neurotoxicity such as lowered intelligence and cognitive impairment. Oxidative damage is critical to pathophysiologic processes of fluoride intoxication, and neurotoxicity of fluoride may be associated with oxidative stress. In previous studies, maize purple plant pigment (MPPP), which was rich in anthocyanins, showed a strong scavenging
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Plasma cholesterol in Alzheimer’s disease and frontotemporal dementia Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-18 Pan Wang; Huihong Zhang; Yan Wang; Miao Zhang; Yuying Zhou
The relationship between the apolipoprotein E (APOE)-ε4 allele, triglyceride (TG) level, and cholesterol level and an increased risk of developing Alzheimer’s disease (AD) has been well established, but their relationship with behavioral-variant frontotemporal dementia (bvFTD) is not well-known.
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miR-142-3p suppresses apoptosis in spinal cord-injured rats Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-18 Jun Zheng; Jing Kuang; Xianyu Zhang; Daya Luo; Weijing Liao
Spinal cord injury (SCI) leads to abnormal expression of miRs, leading to secondary responses such as oxidative stress, inflammation and apoptosis. In the present work, we screened the miRs involved and the associated pathway.
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Neuroprotective mechanisms of erythropoietin in a rat stroke model Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-18 Martin Juenemann; Tobias Braun; Nadine Schleicher; Mesut Yeniguen; Patrick Schramm; Tibo Gerriets; Nouha Ritschel; Georg Bachmann; Martin Obert; Markus Schoenburg; Manfred Kaps; Marlene Tschernatsch
This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).
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Efficacy of Novavit in ameliorating the neurotoxicity of propionic acid Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-26 Sarah I. Bukhari; Hanan Alfawaz; Abeer Al-Dbass; Ramesa Shafi Bhat; Nadine MS Moubayed; Wadha Bukhari; Sohair A. Hassan; Nada Merghani; Samar Elsamaligy; Afaf El-Ansary
Oxidative stress, abnormal fatty acid metabolism, and impaired gut microbiota play a serious role in the pathology of autism. The use of dietary supplements to improve the core symptoms of autism is a common therapeutic strategy. The present study analyzed the effects of oral supplementation with Novavit, a multi-ingredient supplement, on ameliorating oxidative stress and impaired lipid metabolism
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Decreased MiR-30a promotes TGF-β1-mediated arachnoid fibrosis in post-hemorrhagic hydrocephalus Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-26 Chaohong Zhan; Gelei Xiao; Xiangyang Zhang; Xiaoyu Chen; Zhiping Zhang; Jingping Liu
Fibrosis in the ventricular system is closely associated with post-hemorrhagic hydrocephalus (PHH). It is characterized by an expansion of the cerebral ventricles due to CSF accumulation following intraventricular hemorrhage (IVH). The activation of transforming growth factor-β1 (TGF-β1) may be involved in thrombin-induced arachnoid fibrosis.
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Ormosanine improves neuronal functions in spinal cord-injured rats by blocking peroxynitrite/calpain activity Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-29 Yan An; Jianing Li; Yajun Liu; Mingxing Fan
The present study was performed to evaluate the effects of ormosanine against spinal cord injury (SCI) in rats and to examine the possible molecular mechanism of action. SCI was induced using an impactor device, and rats were treated with ormosanine 10, 50 or 100 mg/kg, p.o., for 10 days after induction of SCI. The effect of ormosanine on SCI was determined by estimating neurological functions and
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EGCG modulates PKD1 and ferroptosis to promote recovery in ST rats Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-29 Jianjun Wang; Ying Chen; Long Chen; Yanzhi Duan; Xuejun Kuang; Zhao Peng; Conghui Li; Yuanhao Li; Yang Xiao; Hao Jin; Quandan Tan; Shaofeng Zhang; Bopei Zhu; Yinjuan Tang
Spinal cord injury (SCI) causes devastating loss of function and neuronal death without effective treatment. (−)-Epigallocatechin-3-gallate (EGCG) has antioxidant properties and plays an essential role in the nervous system. However, the underlying mechanism by which EGCG promotes neuronal survival and functional recovery in complete spinal cord transection (ST) remains unclear.
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Effect of C-phycocyanin on HDAC3 and miRNA-335 in Alzheimer’s disease Trans. Neurosci. (IF 1.373) Pub Date : 2020-05-29 Zhengyu Li; Li Gan; Si Yan; Yufang Yan; Wei Huang
Amyloid-beta (Aβ) plaque deposits and neurofibrillary tangles containing tau proteins are the key pathognomonic manifestations of Alzheimer’s disease (AD). Lack of holistic drugs for AD has reinvigorated enthusiasm in the natural product-based therapies. In this study, our idea to decipher the beneficial effects of C-phycocyanin (CPC) in the management of AD is buoyed by its multifaceted and holistic
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Development of a trunk motor paradigm for use in neuroimaging Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-01 Elizabeth Saunders; Brian C. Clark; Leatha A. Clark; Dustin R. Grooms
The purpose of this study was to quantify head motion between isometric erector spinae (ES) contraction strategies, paradigms, and intensities in the development of a neuroimaging protocol for the study of neural activity associated with trunk motor control in individuals with low back pain. Ten healthy participants completed two contraction strategies; (1) a supine upper spine (US) press and (2) a
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High-fat diet-induced obesity and impairment of brain neurotransmitter pool Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-01 Ranyah Shaker M. Labban; Hanan Alfawaz; Ahmed T. Almnaizel; Wail M. Hassan; Ramesa Shafi Bhat; Nadine MS Moubayed; Geir Bjørklund; Afaf El-Ansary
Obesity and the brain are linked since the brain can control the weight of the body through its neurotransmitters. The aim of the present study was to investigate the effect of high-fat diet (HFD)-induced obesity on brain functioning through the measurement of brain glutamate, dopamine, and serotonin metabolic pools. In the present study, two groups of rats served as subjects. Group 1 was fed a normal
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The “authentic subjective experience” of memory in Alzheimer’s disease Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-03 Mohamad El Haj; Ahmed A. Moustafa; Jean Roche; Florence Pasquier; Dimitrios Kapogiannis; Karim Gallouj; Pascal Antoine
Most research has mainly focused on the decline of the subjective experience in Alzheimer’s disease (AD). However, few attempts have been made to evaluate whether subjective experience may be maintained in AD. In this narrative review, we attempt to provide a positive view, according to which patients with AD can enjoy, to some extent, subjective experience during memory retrieval. Memory and expression
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Erratum to “Changing the tone of clinical study design in the cannabis industry” Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-03 Joseph M. Antony; Alison C. McDonald; Farshid Noorbakhsh; Najla Guthrie; Mal Evans
Journal Name: Translational Neuroscience Volume: 11 Issue: 1 Pages: 192-192
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A novel low-cost electrode for recording the local field potential of freely moving rat’s brain Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-05 Xue-Feng Ding; Yan Gao; Hui Zhang; Yuan Zhang; Shao-Xia Wang; Yong-Qi Zhao; Yi-Zheng Wang; Ming Fan
Local field potentials (LFPs) are involved in almost all cognitive activities of animals. Several kinds of recording electrodes are used for recording LFPs in freely moving animals, including commercial and homemade electrodes. However, commercial recording electrodes are expensive, and their relatively fixed size often causes a steric hindrance effect, especially when combining deep brain stimulation
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Dysbiosis characteristics of gut microbiota in cerebral infarction patients Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-08 Hao Li; Xiaohui Zhang; Dengdeng Pan; Yongqiang Liu; Xuebing Yan; Yihan Tang; Mingyang Tao; Li Gong; Ting Zhang; Christian Rutan Woods; Yong Du; Renyuan Gao; Huanlong Qin
The aim of this study is to investigate the dysbiosis characteristics of gut microbiota in patients with cerebral infarction (CI) and its clinical implications.
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A comment on Morey et al. (2020) Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-15 Seth M. Levine
Journal Name: Translational Neuroscience Volume: 11 Issue: 1 Pages: 208-209
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Clinical and imaging features of reversible splenial lesion syndrome with language disorder Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-19 Yi Tang; Dong Zhang; Jian Ge; Jing Jin; Yumeng Liu; Siyuan Chen; Mingli He
Reversible splenial lesion syndrome (RESLES) is a single-stage non-specific syndrome with unclear pathogenesis. There has been no report on answer delay in patients with RESLES. We report a female patient who was admitted to our department for mixed aphasia accompanied by cognitive impairment. During the rapid improvement of aphasia, there was a clear phase of language output response delay accompanied
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Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity Trans. Neurosci. (IF 1.373) Pub Date : 2020-06-22 Yibing Zhang; Yong Zhao; Yongwang Ran; Jianyou Guo; Haifeng Cui; Sha Liu
Sevoflurane, a volatile anesthetic, is known to induce widespread neuronal degeneration and apoptosis. Recently, the stress-inducible protein sestrin 2 and adenosine monophosphate-activated protein kinase (AMPK) have been found to regulate the levels of intracellular reactive oxygen species (ROS) and suppress oxidative stress. Notoginsenoside R1 (NGR1), a saponin isolated from Panax notoginseng, has
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Compression of the lateral antebrachial cutaneous nerve by a traumatic arteriovenous fistula Trans. Neurosci. (IF 1.373) Pub Date : 2020-04-20 Min Cheol Chang; Mathieu Boudier-Revéret; Ming-Yen Hsiao
Journal Name: Translational Neuroscience Volume: 11 Issue: 1 Pages: 87-88
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Hydrochloride fasudil attenuates brain injury in ICH rats Trans. Neurosci. (IF 1.373) Pub Date : 2020-04-20 Limin Li; Xiaoli Lou; Kunlun Zhang; Fangping Yu; Yingchun Zhao; Ping Jiang
The aim of this study was to investigate the neuroprotective effects of hydrochloride fasudil (HF) in rats following intracerebral hemorrhage (ICH).
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A Moving Residual Limb: Botulinum Toxin to the Rescue Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-29 Marie-Michèle Briand; Mathieu Boudier-Réveret; Xavier Rodrigue; Geneviève Sirois; Min Cheol Chang
Movement disorders post-amputation are a rare complication and can manifest as the jumping stump phenomenon, a form of peripheral myoclonus. The pathophysiology remains unknown and there is currently no standardized treatment. We describe the case of a 57-year-old male with unremitting stump myoclonus, starting one month after transtibial amputation, in his residual limb without associated phantom
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Integrated Chinese and western medicine for acute guillain-barré syndrome treatment Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-29 Liu Yang; Xiumin Zhao
Guillain-Barré syndrome (GBS) is a worldwide demyelinating polyradiculopathy and polyneuropathy. Currently, there is no specific drug for GBS, and established treatment is generally based on immune-modulating treatment with plasma exchange or intravenous immunoglobulin in combination with supportive care. This study aimed to investigate the efficiency of integrated Chinese and Western medicine for
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Advances in transcription factors related to neuroglial cell reprogramming Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-20 Kuangpin Liu; Wei Ma; Chunyan Li; Junjun Li; Xingkui Zhang; Jie Liu; Wei Liu; Zheng Wu; Chenghao Zang; Yu Liang; Jianhui Guo; Liyan Li
Neuroglial cells have a high level of plasticity, and many types of these cells are present in the nervous system. Neuroglial cells provide diverse therapeutic targets for neurological diseases and injury repair. Cell reprogramming technology provides an efficient pathway for cell transformation during neural regeneration, while transcription factor-mediated reprogramming can facilitate the understanding
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A case of primary central nervous system lymphoma mimic neuromyelitis optica Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-18 Xixi Sheng; Mingwei Xu; Xia Li
Primary central nervous system lymphoma (PCNSL) is rare. And the symptoms of PCNSL are atypical, it is extremely easy to be misdiagnosed as other diseases. However, early treatment is crucial which is requesting early diagnosis. We report a case of a 47-year-old man who was initially diagnosed as neuromyelitis optica (NMO) on the basis of clinical findings, slightly high Aquaporin4 (AQP4) (1:10) and
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Changing the Tone of Clinical Study Design in the Cannabis Industry. Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-13 Joseph M Antony,Alison C McDonald,Farshid Noorbhaksh,Najla Guthrie,Mal Evans
Cannabis (also known as marijuana) is the most frequently used psychoactive substance globally. Cannabis exerts therapeutic functions for many indications and has vast potential as a health and wellness product. Advances in our understanding of the composition and pharmacological properties of cannabis have revealed interactions between cannabis, an individuals’ circadian rhythms and their endocannabinoid
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Anticholinergic Drugs and Oral Health-related Quality of Life in Patients with Schizophrenia: A Pilot Study. Trans. Neurosci. (IF 1.373) Pub Date : 2020-02-11 Justine Chapuis,Francesca Siu-Paredes,Claire Pavageau,Gilles Amador,Nathalie Rude,Frédéric Denis
The aim of this study was to explore, in a sample population of people with schizophrenia (PWS), the role of the anticholinergic burden on the perception of oral health-related quality of life (OHrQoL) in France.
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Ataxic Hemiparesis after Corona Radiata Infarct: Diffusion Tensor Imaging Correlation of Corticoponto-cerebellar Tract Injury. Trans. Neurosci. (IF 1.373) Pub Date : 2020-01-31 Jun Young Kim,Jeong Pyo Seo,Min Cheol Chang
Journal Name: Translational Neuroscience Volume: 11 Issue: 1 Pages: 1-3
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Interactions of Aromatase and Seladin-1: A Neurosteroidogenic and Gender Perspective. Trans. Neurosci. (IF 1.373) Pub Date : 2019-11-19 Pelin Kelicen-Ugur,Mehtap Cincioğlu-Palabıyık,Hande Çelik,Hande Karahan
Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key enzyme that catalyzes estrogen biosynthesis from androgen precursors and regulates the brain's neurosteroidogenic activity. Seladin-1 is the enzyme that catalyzes the last step in the biosynthesis of cholesterol, the precursor of all hormones
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Chronic Subdural Hematoma (CSH) is Still an Important Clinical Problem. Analysis of 700 Consecutive Patients. Trans. Neurosci. (IF 1.373) Pub Date : 2019-11-19 Zbigniew Kotwica,Agnieszka Saracen,Ireneusz Dziuba
Background Chronic subdural hematoma (CSH) is still an important neurosurgical problem and the number of patients increases despite the progress in early diagnosis of cerebral lesions. Methodology We analyzed a group of 700 consecutive patients treated in neurosurgical departments for CSH. Clinical state on admission was evaluated according to the Markwalder scale, all patients had CT studies and were
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Processing of Action and Sound Verbs in Context: An FMRI Study. Trans. Neurosci. (IF 1.373) Pub Date : 2019-10-23 Margot Popp,Natalie M Trumpp,Markus Kiefer
Recent theories propose a flexible recruitment of sensory and motor brain regions during conceptual processing depending on context and task. The present functional magnetic resonance imaging study investigated the influence of context and task on conceptual processing of action and sound verbs. Participants first performed an explicit semantic context decision task, in which action and sound verbs
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Behavior and Hippocampal Epac Signaling to Nicotine CPP in Mice. Trans. Neurosci. (IF 1.373) Pub Date : 2019-10-23 Jing Liu,Xinrong Tao,Fei Liu,Yuting Hu,Song Xue,Qi Wang,Bing Li,Rongbo Zhang
Tobacco use is a major challenge to public health in the United States and across the world. Many studies have demonstrated that adult men and women differ in their responses to tobacco smoking, however neurobiological studies about the effect of smoking on males and females were limited. Exchange protein directly activated by cAMP (Epac) signaling participates in drug addictive behaviors. In this
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