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Undaria pinnatifida ameliorates nasal inflammation by inhibiting eosinophil and mast cell activation and modulating the NF‐κB/MAPKs signaling pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-16 Zhen Nan Yu, Yan Jing Fan, Thi Van Nguyen, Chun Hua Piao, Byung‐Hoo Lee, So‐Young Lee, Hee Soon Shin, Chang Ho Song, Ok Hee Chai
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Anti‐inflammatory potential of remimazolam: A laboratory and clinical investigation Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-14 Shota Tsukimoto, Atsuhiro Kitaura, Hidetaka Kuroda, Uno Imaizumi, Fumihiko Yoshino, Ayaka Yoshida, Shinchi Nakao, Noriyuki Ohta, Yasuhumi Nakajima, Takuro Sanuki
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Hmgcs2 is the hub gene in diabetic cardiomyopathy and is negatively regulated by Hmgcs2, promoting high glucose‐induced cardiomyocyte injury Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Ying Wang, Li‐Feng Ping, Fu‐Yan Bai, Xin‐Huan Zhang, Guang‐Hong Li
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Elevated level of circulating calprotectin correlates with severity and high mortality in patients with COVID‐19 Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Haoran Zhang, Qingyu Zhang, Kun Liu, Zenong Yuan, Xiqiang Xu, Jun Dong
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Berberine: A natural modulator of immune cells in multiple sclerosis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-13 Esmaeil Yazdanpanah, Sepehr Dadfar, Alireza Shadab, Niloufar Orooji, MohammadHossein Nemati, Alireza Pazoki, Seyed‐Alireza Esmaeili, Rasoul Baharlou, Dariush Haghmorad
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Regulatory RNAs in immunosenescence Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Atefe Ghamar Talepoor, Mehrnoosh Doroudchi
BackgroundImmunosenescence is a multifactorial stress response to different intrinsic and extrinsic insults that cause immune deterioration and is accompanied by genomic or epigenomic perturbations. It is now widely recognized that genes and proteins contributing in the process of immunosenescence are regulated by various noncoding (nc) RNAs, including microRNAs (miRNAs), long ncRNAs, and circular
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Dietary composition of adult eosinophilic esophagitis patients is related to disease severity Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Simone R. B. M. Eussen, Sanne Wielders, Willemijn E. de Rooij, Marleen T. J. Van Ampting, Betty C. A. M. Van Esch, Jeanne H. M. de Vries, Albert J. Bredenoord, Berber Vlieg‐Boerstra
BackgroundIn addition to the elimination diet, dietary composition may influence disease severity in patients with eosinophilic esophagitis (EoE) through modulation of the immune response.AimTo explore the immunomodulatory role of nutrition before and during elimination diet in adult EoE patients.MethodsNutritional intake was assessed in 39 Dutch adult EoE patients participating in the Supplemental
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A multicenter study of severity and prognosis of symptomatic COVID‐19 in end‐stage renal disease and non‐dialysis patients in East of Iran Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-03-08 Tara Mohsenzadeh, Masood Ziaee, Hamid Salehiniya, Hossein Mohsenzadeh, Amin Mirsani, Vajehallah Raeesi
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Vitamin D improves autoimmune diseases by inhibiting Wnt signaling pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Minshu Zou, Qiuju Song, Taiyong Yin, Hongtao Xu, Guoming Nie
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Comparison of the efficacy and safety of TAF, TDF, and LdT to prevent the transmission of hepatitis B in pregnant women: A retrospective study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Shufang Pan, Ying Zhang, Yingfu Zeng, Chaoshuang Lin
ObjectiveTo compare the efficacy and safety of telbivudine (LdT), tenofovir alafenamide fumarate (TAF), and tenofovir disoproxil fumarate (TDF) for preventing hepatitis B transmission in immune‐tolerant pregnant women with HBV infection.MethodsWe conducted a retrospective cohort study involving women who had hepatitis B virus deoxyribonucleic acid (HBV DNA) ≥ 2 × 105 IU/mL and initiated LdT, TDF, or
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HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-28 Xiaofeng Zhu, Yue Dou, Yawen Lin, Gaoping Chu, Jing Wang, Lei Ma
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Bisdemethoxycurcumin, a curcumin, protects chondrocytes, and reduces cartilage inflammation via the NRF2/HO‐1/NLRP3 pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Gang Jin, Wei Xu, Huilin Tang, Yaying Cui, Han Zhang
BackgroundThe objective of this thesis is to evaluate the effect of bisdemethoxycurcumin (BDMC) on osteoarthritis (OA) and comprehensively evaluate the role of the Nuclear Factor erythroid 2‐Related Factor 2 (Nrf2) signalling pathway in chondrocytes.MethodIn our study, we treated chondrocytes with BDMC in an in vitro chondrocyte assay and measured its influence on extracellular matrix (ECM) expression
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Potency, immunogenicity, and efficacy of rabies vaccine: In vitro and in vivo approach Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Fahima Akter, Md. Shamimuzzaman
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Prevalence of latent tuberculosis infection in Asian nations: A systematic review and meta‐analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Abhigan B. Shrestha, Imran S. Siam, Jarin Tasnim, Abhinav Dahal, Poulami Roy, Sushil Neupane, Ashok Adhikari, Barsha Khanal, Rupesh Ghimirie, Dikshya Shrestha, Suju Bhattarai, Sajina Shrestha, Nischal Mainali, Yub Raj Sedhai, Uday Singh
BackgroundTuberculosis (TB) is a serious public health concern around the world including Asia. TB burden is high in Asian countries and significant population harbor latent tuberculosis infection(LTBI).AimThis systematic review and meta‐analysis aims to evaluate the prevalence of LTBI in Asian countries.MethodWe performed a systematic literature search on PubMed, Embase, and ScienceDirect to identify
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Histiocytic necrotizing lymphadenitis with hemophagocytic lymphohistiocytosis in adults: A single‐center analysis of 5 cases Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Qingqing Chen, Jing Zhang, Huijun Huang, Tonglu Qiu, Ze Jin, Yu Shi, Huayuan Zhu, Lei Fan, Jianyong Li, Wenyu Shi, Yi Miao
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The relationship between inflammatory cytokines and in‐hospital complications of acute pancreatitis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Jiaxin Yao, Shuangshuang Zhang, Fei Zhou, Mengting Zhuang, Sujuan Fei
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KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Yuan Chen, Lifeng Sun, Haiyan Liu, Jiamei Li, Lu Guo, Zhiyi Wang
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Dexmedetomidine activates the PKA/CREB pathway and inhibits proinflammatory factor expression through β2 adrenergic receptors Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-27 Baocheng Zhang, Jie Shen
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The role of interleukin-22 in mammalian intestinal homeostasis: Friend and foe Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-16 Hedi-Britt Klotskova, Evelien Kidess, Adria L. Nadal, Sylvia Brugman
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High CRP/PNI levels predict an unfavorable prognosis in severe fever with thrombocytopenia syndrome: A propensity score matching study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-20 Chunxia Guo, Huan Wang, Xiaorong Wang, Shan Tian
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A bibliometric analysis of the research status and trends in studies on polymyositis and dermatomyositis with interstitial lung disease from 2000 to 2022 using Web of Science Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-20 Xiao‐Na Ma, Wei Feng, Shu‐Lin Chen, Xiao‐Qin Zhong, Xue‐Xia Zheng, Chang‐Song Lin, Qiang Xu
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Resveratrol attenuates intestinal epithelial barrier dysfunction via Nrf2/HO‐1 pathway in dextran sulfate sodium‐induced Caco‐2 cells Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-19 Xinya Yu, Yazhi Wang, Yunchun Xu, Xiaoxi Li, Junhua Zhang, Yunpeng Su, Le Guo
IntroductionThe intestinal tract serves as an innate barrier, safeguarding the internal milieu from microorganisms and toxins. Various intestinal inflammatory diseases have a strong association with intestinal barrier dysfunction. The primary functional cells within the intestinal tract, intestinal epithelial cells (IECs) and their tight junctions (TJs), are crucial in preserving the integrity of this
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PPM1G regulates hepatic ischemia/reperfusion injury through STING‐mediated inflammatory pathways in macrophages Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-19 Dadi Peng, Zuotian Huang, Hang Yang, Yunhai Luo, Zhongjun Wu
BackgroundIschemia/reperfusion injury (IRI) is generally unavoidable following liver transplantation. Here, we investigated the role of protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G) in hepatic IRI.MethodsHepatic IRI was mimicked by employing a hypoxia/reperfusion (H/R) model in RAW 264.7 cells and a 70% warm ischemia model in C57BL/6 mice, respectively. In vitro, expression changes of tumor necrosis
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Quercetin attenuates inflammation in LPS-induced lung epithelial cells via the Nrf2 signaling pathway Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-14 Pengju Lv, Pengli Han, Yuanbo Cui, Qiusheng Chen, Wei Cao
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Autophagy-related genes polymorphism in hepatitis B virus-associated hepatocellular carcinoma: A systematic review Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-14 Parastoo Yousefi, Alireza Tabibzadeh, Abdulhussain Kadhim Jawaziri, Mohsen Mehrjoo, Mandana Akhavan, Leila Allahqoli, Hamid Salehiniya
Chronic hepatitis B (CHB) virus is the most common risk factor for developing liver malignancy. Autophagy is an essential element in human cell maintenance. Several studies have demonstrated that autophagy plays a vital role in liver cancer at different stages. In this systematic review, we intend to investigate the role of polymorphism and mutations of autophagy-related genes (ATGs) in the pathogenesis
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Association between preoperative systemic immune inflammation index and postoperative sepsis in patients with intestinal obstruction: A retrospective observational cohort study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-14 Jirong Yang, Taojia Ran, Xiaoyu Lin, Jinyan Xu, Shaoli Zhou, Chaojin Chen, Pinjie Huang
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NR5A2 promotes malignancy progression and mediates the effect of cisplatin in cutaneous squamous cell carcinoma Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-15 Wang Ye, Cao Ya-xuan, Tang Shan-shan, Long Qiu, Ma Ting, Chen Shao-jie, Cao Yu
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Galectin-9 alleviates acute graft-versus-host disease after haplo-hematopoietic stem cell transplantation by regulating regulatory T cell/effector T cell imbalance Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-14 Nannan Pang, Shabaaiti Tudahong, Yuejie Zhu, Jiang He, Chunxia Han, Gang Chen, Weiguo Wang, Jing Wang, Jianbing Ding
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Intestinal mRNA expression analysis of polarity-related genes identified the discriminatory ability of CRB3 as a diagnostic marker for celiac disease Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-14 Tannaz Taraz, Nastaran Asri, Ehsan Nazemalhosseini-Mojarad, Flora Forouzesh, Mostafa Rezaei-Tavirani, Mohammad Rostami-Nejad
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Distinct cross talk of IL-17 & TGF-β with the immature CD11c+TRAF6(−/−)-null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-08 Yen Chun G. Liu, Andy Yen-Tung Teng
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Three cases of systemic lupus erythematosus presenting with ischemic stroke as the initial symptom: Case reports and literature review Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-08 Na Li, Xiaoxia Liu, Pengjia Wu, Jun Liu, Pengyu Chen, Jiashun Zeng
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Impact of occupational hazards on neurological health status in Pakistan: Challenges and recommendations Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-07 Zoaib Habib Tharwani, Yumna Salman, Maryam Irshad, Mariam Adnan Rizvi, Muhammad Hasanain, Abdullah Malikzai
1 INTRODUCTION The European Agency for Safety and Health at Work defines occupational hazards as short- and long-term workplace dangers that impair the health and well-being of employees.1 The Occupational Safety and Health Administration (OSHA) has classified these dangers into six categories: safety, physical, chemical, biological, ergonomic, and work organization or psychosocial hazards.2 The severity
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Therapeutic potential of dihydroartemisinin in mitigating radiation-induced lung injury: Inhibition of ferroptosis through Nrf2/HO-1 pathways in mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-05 Xin Ning, Weidong Zhao, Qiaoyuan Wu, Cailan Wang, Shixiong Liang
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The role of the CX3CL1/CX3CR1 axis as potential inflammatory biomarkers in subjects with periodontitis and rheumatoid arthritis: A systematic review Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-06 Mario A. Alarcón-Sánchez, Julieta S. Becerra-Ruiz, Celia Guerrero-Velázquez, Seyed A. Mosaddad, Artak Heboyan
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Genetic determinants of SARS-CoV-2 and the clinical outcome of COVID-19 in Southern Bangladesh Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-06 Md. Mahbub Hasan, Chayan Kumar Saha, H. M. Hamidullah Mehedi, Kallyan Chakma, Asma Salauddin, Md. Shakhawat Hossain, Farjana Sharmen, S. M. Rafiqul Islam, Afroza Akter Tanni, Farhana Yasmin, Al-Shahriar Akash, Mohammad Enayet Hossain, Mojnu Miah, Sanjoy Kanti Biswas, Nahid Sultana, Adnan Mannan
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Sirtuin2 suppresses the polarization of regulatory T cells toward T helper 17 cells through repressing the expression of signal transducer and activator of transcription 3 in a mouse colitis model Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Liuqing Ge, Min Xu, Meifang Huang, Shaoping Liu, Zhidai Zhou, Ziqin Xia, Qiu Zhao, Feng Zhou
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MiR-9-enriched mesenchymal stem cells derived exosomes prevent cystitis-induced bladder pain via suppressing TLR4/NLRP3 pathway in interstitial cystitis mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Xiangrong Cui, Xingyu Bi, Xiuping Zhang, Zhiping Zhang, Qin Yan, Yanni Wang, Xia Huang, Xueqing Wu, Xuan Jing, Hongwei Wang
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Timing of initial symptom onset during milk and wheat challenges: A retrospective study Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Noriyuki Yanagida, Takanori Minoura, Sakura Sato, Kyohei Takahashi, Ken-ichi Nagakura, Kiyotake Ogura, Takaaki Itonaga, Yoko Miura, Naoko Fusayasu, Motohiro Ebisawa
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Silencing of secreted phosphoprotein 1 attenuates sciatic nerve injury-induced neuropathic pain: Regulating extracellular signal-regulated kinase and neuroinflammatory signaling pathways Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Haiyu Xie, Feng Lu, Xiaoling Li, Enfu Wang, Jiao Mo, Weidong Liang
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Effects of myeloperoxidase on inflammatory responses with hypoxia in Citrobacter rodentium-infectious mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Xiang Gao, Yu Zhang, Qinfang Zhu, Ying Han, Ruhan Jia, Wei Zhang
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Knockdown of liver cancer cell-secreted exosomal PSMA5 controls macrophage polarization to restrain cancer progression by blocking JAK2/STAT3 signaling Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-02 Shujie Xie, Xiang Li, Jia Yan, Hua Yu, Shuhuai Chen, Kana Chen
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Elucidating systemic immune responses to acute and convalescent SARS-CoV-2 infection in children and elderly individuals Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-01 Anuradha Rajamanickam, Pavan Kumar Nathella, Aishwarya Venkataraman, Padmapriyadarsini Chandrasekaran, Sasidaran Rajendraprasath, Bella D. Devaleenal, Arul Nancy Pandiarajan, Gowshika Krishnakumar, Padmasani Venkat Ramanan, Subash Babu
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Potential clinical implications of molecular mimicry-induced autoimmunity Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-01 Bandar A Suliman
Molecular mimicry is hypothesized to be a mechanism by which autoimmune diseases are triggered. It refers to sequence or structural homology between foreign antigens and self-antigens, which can activate cross-reactive lymphocytes that attack host tissues. Elucidating the role of molecular mimicry in human autoimmunity could have important clinical implications.
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Adalimumab exhibits superiority over etanercept in terms of a numerically higher response rate and equivalent adverse events: A real-world finding Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-01 Zhe Yu, Ling Gao, Yinshan Zang, Lu Cheng, Wenjia Gao, Yan Xu
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Inflammatory biomarker changes in healthy adults secondary to electronic cigarette use: A scoping review Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-01 Shawn Boss, Michael Bertolio, Laura Lipke
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Serological detection of Newcastle disease virus in backyard poultry production system in Woliso District South West Shewa, Central Ethiopia Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-02-01 Alemayehu Choramo, Motuma Debelo, Asamenew Tesfaye, Chala Bedasa, Chala Dima, Chala Guyassa
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Efficacy, safety and the lymphocyte subsets changes of low-dose IL-2 in patients with systemic lupus erythematosus: A systematic review and meta-analysis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-24 Qin-Yi Su, Jing Luo, Xin-Miao Wang, Jing-Kai Di, Yi-Xin Cao, Sheng-Xiao Zhang
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Circ_0087199 depletion attenuates lipopolysaccharides-induced human periodontal ligament cell injury through the miR-527/TLR4 axis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-24 Jing Wang, Na Huo, Chuan Cai, Yu Zhang, Rui Xiao
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Cordyceps cicadae ameliorates inflammatory responses, oxidative stress, and fibrosis by targeting the PI3K/mTOR-mediated autophagy pathway in the renal of MRL/lpr mice Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-24 Feng Yang, Yanyan Zhang, Lei Dong, Zhichao Song
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Exploring the effect of LncRNA DANCR to regulate the Keap1-Nrf2/ARE pathway on oxidative stress in rheumatoid arthritis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-24 Shaohong Cai, Yue Sun, Yuan Wang, Zhangying Lin
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Bibliometric analysis of mucosal immunity in IgA nephropathy from 1990 to 2022 Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-24 Xian Chen, Zhe Yan, Qing Pan, Chunxia Zhang, Yakun Chen, Xuzhi Liang, Shaomei Li, Gang Wu
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Social determinants of health disparities in Staten Island compared with Manhattan, Queens, Brooklyn, and the Bronx: Contribution to COVID-19 outcomes Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Masha Kolesnikova, Haram Abdelmajid, Stephan Kohlhoff, Tamar A. Smith-Norowitz
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Eliciting and stop dose during oral food challenges for peanut and common tree nuts in different age groups Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Wouter W. de Weger, Diede Jansen, Lidy van Lente, Gerbrich N. van der Meulen, Arvid W. A. Kamps
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Metformin inhibits high glucose-induced apoptosis of renal podocyte through regulating miR-34a/SIRT1 axis Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Xudong Zhuang, Zhuye Sun, Huasheng Du, Tianhui Zhou, Jing Zou, Wei Fu
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Clinical performance of AMA-M2, anti-gp210 and anti-sp100 antibody levels in primary biliary cholangitis: When detected by multiplex bead-based flow fluorescent immunoassay Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Zhan Wang, Yongxin Li, Lisheng Ren, Yujie Li, Tiantian Xu, Wenshuai Li, Weize Gao, Guirong Sun, Mingjun Liu
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The functional role of CST1 and CCL26 in asthma development Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Angela Hoyer, Sandip Chakraborty, Ingrid Lilienthal, Jon R. Konradsen, Shintaro Katayama, Cilla Söderhäll
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Effect of serum inflammatory factors in predicting co-infection with influenza viruses and Omicron Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-22 Chengli Zhang, Wei Wang, Xianglin Luo, Minggang Yin, Xiaolong Guo
To identify the key differences in laboratory indicators between mono-infection and co-infection by influenza viruses and Omicron to facilitate timely adjustments in patient treatment strategies.
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Alleviating effect of Nexrutine on mucosal inflammation in mice with ulcerative colitis: Involvement of the RELA suppression Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-19 Hongyun Xu, Chunyu Wu, Danning Wang, Haiqiang Wang
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m5C regulator-mediated methylation modification patterns and tumor microenvironment infiltration characteristics in acute myeloid leukemia Immun. Inflamm. Dis. (IF 2.493) Pub Date : 2024-01-22 Qiang Wen, ShouJun Wang, Lili Hong, Siyu Shen, Yibo He, Xianfu Sheng, Xiaofen Zhuang, Shiliang Chen, Ying Wang, Haifeng Zhuang
Recently, many studies have been conducted to examine immune response modification at epigenetic level, but the candidate effect of RNA 5-methylcytosine (m5C) modification on tumor microenvironment (TME) of acute myeloid leukemia (AML) is still unknown at present.