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Development of a prognostic index based on immunogenomic landscape analysis in glioma Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-27 Haitao Luo; Chuming Tao; Peng Wang; Jingying Li; Kai Huang; Xingen Zhu
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Anti‐dsDNA, anti‐nucleosome, anti‐C1q, and anti‐histone antibodies as markers of active lupus nephritis and systemic lupus erythematosus disease activity Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-20 Xiaoying Shang; Lisheng Ren; Guirong Sun; Teng Yu; Yuan Yao; Lin Wang; Fenghai Liu; Lijun Zhang; Xiaqin He; Mingjun Liu
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Enhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-20 Taira Ariyoshi; Junichiro Tezuka; Hiroki Yasudo; Yasufumi Sakata; Tamaki Nakamura; Takeshi Matsushige; Hideki Hasegawa; Noriko Nakajima; Akira Ainai; Atsunori Oga; Hiroshi Itoh; Komei Shirabe; Shoichi Toda; Ryo Atsuta; Shouichi Ohga; Shunji Hasegawa
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Efficacy of canakinumab in mild or severe COVID‐19 pneumonia Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-19 Falasca Katia; Di Penta Myriam; Claudio Ucciferri; Antonio Auricchio; Marta Di Nicola; Michele Marchioni; Celletti Eleonora; Sabatini Emanuela; Francesco Cipollone; Jacopo Vecchiet
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Disease‐duration based comparison of subsets of immune cells in SARS CoV‐2 infected patients presenting with mild or severe symptoms identifies prognostic markers for severity Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-16 Archana Kulkarni‐Munje; Sonali Palkar; Shubham Shrivastava; Sanjay Lalwani; Akhilesh C. Mishra; Vidya A. Arankalle
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Clinical efficacy and safety of omalizumab in conventional treatment‐resistant vernal keratoconjunctivitis: Our experience and literature review Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-12 Sara Manti; Giuseppe Fabio Parisi; Maria Papale; Gian Luigi Marseglia; Amelia Licari; Salvatore Leonardi
1 INTRODUCTION Vernal keratoconjunctivitis (VKC) is a severe ocular disease characterized by recurring acute and/or chronic corneal‐conjunctival inflammation leading to visual sequelae.1 Since no treatments are universally effective in the management of VKC, novel therapies are currently under investigation, including anti‐immunoglobulin E (IgE). Although the efficacy and safety of omalizumab have
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RNA m6A methylation regulates virus–host interaction and EBNA2 expression during Epstein–Barr virus infection Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-12 Xiang Zheng; Jia Wang; Xiaoyue Zhang; Yuxin Fu; Qiu Peng; Jianhong Lu; Lingyu Wei; Zhengshuo Li; Can Liu; Yangge Wu; Qun Yan; Jian Ma
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Establishment and characterization of murine models of asthma and subcutaneous immunotherapy for Humulus pollen allergy Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-12 Guang P. Xi; Qian Zhang; Jia Yin
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Serum soluble PD‐1 plays a role in predicting infection complications in patients with acute pancreatitis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-08 Xingxing Yu; Yu Pan; Qinglin Fei; Xianchao Lin; Zhijiang Chen; Heguang Huang
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Factors affecting upper airway control of NSAID‐exacerbated respiratory disease: A real‐world study of 167 patients Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2021-01-05 Annina Lyly; Anu Laulajainen‐Hongisto; Heikki Turpeinen; Seija I. Vento; Jyri Myller; Jura Numminen; Saara Sillanpää; Johanna Sahlman; Paula Kauppi; Sanna Toppila‐Salmi
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Systemic immune responses in patients with early localized or early disseminated Borrelia afzelii lyme borreliosis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-31 Tjaša Cerar Kišek; Rok Blagus; Eva Ružić‐Sabljić; Stefan Collinet‐Adler; Fajko F. Bajrović; Daša Stupica
The role of host immune responses in the pathogenesis of borrelial dissemination in early Lyme borreliosis (LB) in the form of multiple erythema migrans (MEM) or LB‐associated symptoms is incompletely understood.
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Serum proteome‐wide identified ATP citrate lyase as a novel informative diagnostic and prognostic biomarker in pediatric sepsis: A pilot study Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-30 Chunxia Wang; Xiaodong Zhu; Yun Cui; Huijie Miao; Yaya Xu; Xi Xiong; Xiaomeng Tang; Lujing Shao; Yucai Zhang
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Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-24 Hiroshi Kawano; Kazuya Koyama; Haruka Nishimura; Yuko Toyoda; Kozo Kagawa; Seidai Sato; Nobuhito Naito; Hisatsugu Goto; Yutaka Inagaki; Yasuhiko Nishioka
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Separate signaling events control TCR downregulation and T cell activation in primary human T cells Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-22 Lieve E. H. van der Donk; Louis S. Ates; Jet van der Spek; Laura M. Tukker; Teunis B. H. Geijtenbeek; Jeroen W. J. van Heijst
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Does COVID‐19 contribute to development of neurological disease? Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Arehally M. Mahalakshmi; Bipul Ray; Sunanda Tuladhar; Abid Bhat; Shasthara Paneyala; Duraisamy Patteswari; Meena Kishore Sakharkar; Hamdan Hamdan; David M. Ojcius; Srinivasa Rao Bolla; Musthafa Mohamed Essa; Saravana Babu Chidambaram; M. Walid Qoronbfleh
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Inflammation initiates a vicious cycle between obesity and nonalcoholic fatty liver disease Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Yunfei Luo; Hui Lin
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MicroRNA‐425‐3p inhibits myocardial inflammation and cardiomyocyte apoptosis in mice with viral myocarditis through targeting TGF‐β1 Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Junhua Li; Jiehong Tu; Hong Gao; Lu Tang
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Sex discrepancy in the reduction of mucosal‐associated invariant T cells caused by obesity Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Jianyun Liu; Hongmei Nan; Randy R Brutkiewicz; Jose Casasnovas; Kok Lim Kua
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The BTLA and PD‐1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Hyun J. Hwang; Jae J. Lee; Sung H. Kang; Jin K. Suh; Eun S. Choi; Seongsoo Jang; Sang‐Hyun Hwang; Kyung‐Nam Koh; Ho J. Im; Nayoung Kim
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miR‐223 improves intestinal inflammation through inhibiting the IL‐6/STAT3 signaling pathway in dextran sodium sulfate‐induced experimental colitis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-17 Juanjuan Zhang; Chenyang Wang; Zhen Guo; Binlin Da; Weiming Zhu; Qiurong Li
The pathogenesis of inflammatory bowel disease (IBD) has not yet been clarified and is closely related to several pro‐inflammatory factors. MicroRNA‐233 (miR‐223) might be involved in the development of IBD; however, the mechanism underlying its pathogenesis is unclear. In this study, we attempted to determine the role of miR‐223 in dextran sodium sulfate (DSS)‐induced colitis and explore the involvement
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Evidence and implications of pre‐existing humoral cross‐reactive immunity to SARS‐CoV‐2 Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-15 Amandine Mveang Nzoghe; Paulin N. Essone; Marielle Leboueny; Anicet Christel Maloupazoa Siawaya; Eliode Cyrien Bongho; Ofilia Mvoundza Ndjindji; Rotimi Myrabelle Avome Houechenou; Selidji Todagbe Agnandji; Joel Fleury Djoba Siawaya
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Association of a four‐gene model with allergic diseases: Two‐year follow‐up of a birth cohort study Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-05 Li Hua; Fen Yang; Qian Chen; Quanhua Liu; Ruoxu Ji; Haipei Liu; Jianmin Ye; Jun Zhang; Jianhua Zhang; Yixiao Bao
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Prognostic value of lipid metabolism‐related genes in head and neck squamous cell carcinoma Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-05 Ying Xiong; Yu Si; Yisi Feng; Shipei Zhuo; Bozhen Cui; Zhigang Zhang
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Silenced SOX2‐OT alleviates ventricular arrhythmia associated with heart failure by inhibiting NLRP3 expression via regulating miR‐2355‐3p Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-03 Yuming Liang; Boqun Wang; Huijuan Huang; Maoyun Wang; Qianwen Wu; Yaxin Zhao; Yan He
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Dec2 attenuates autophagy in inflamed periodontal tissues Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-03 Shunichi Oka; Xiaoyan Li; Fuyuki Sato; Fengzhu Zhang; Nitesh Tewari; Chongchong Chen; Liangjun Zhong; Makoto Makishima; Yi Liu; Ujjal K. Bhawal
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Eradication of hepatitis C virus infection in kidney transplant recipients using direct‐acting antiviral therapy: Qatar experience Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-12-02 Mohamad M. Alkadi; Essa A. Abuhelaiqa; Mostafa F. Elshirbeny; Ahmed F. Hamdi; Omar M. Fituri; Muhammad Asim; Saad R. Alkaabi; Moutaz F. Derbala; Mona E. Jarman; Adel M. Ashour; Awais Nauman; Yousuf K. Al Maslamani; Adeel A. Butt; Hassan A. Al‐Malki
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Rhinovirus remains prevalent in school teenagers during fight against COVID‐19 pandemic Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-28 Di Wu; Jianyun Lu; Zhangyu Sun; Lan Cao; Qing Zeng; Qun Liu; Tiantian Wu; Zhicong Yang
The coronavirus disease 2019 (COVID‐19) caused by the severe acute respiratory syndrome coronavirus 2 is now being a disaster, as of November 3, 2020, the World Health Organization have reported 46 million cases and 1.2 million deaths globally.1 Studies have reported that respiratory infectious diseases such as influenza, varicella, herpes zoster, rubella, and measles are suppressed during the fight
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Safety of hydroxychloroquine for treatment or prevention of SARS‐CoV‐2 infection: A rapid systematic review and meta‐analysis of randomized clinical trials Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-26 Alberto Enrico Maraolo; Adriano Grossi
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Impaired interferon‐α expression in plasmacytoid dendritic cells in asthma Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-25 Ting‐Yu Lin; Chun‐Yu Lo; Kuo‐Chien Tsao; Po‐Jui Chang; Chih‐His Scott Kuo; Yu‐Lun Lo; Shu‐Min Lin; Meng‐Heng Hsieh; Tsai‐Yu Wang; Ping‐Chih Hsu; Horng‐Chyuan Lin
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Enhanced IgG1‐mediated antibody response towards thymus‐dependent immunization in CXCR1‐deficient mice Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-23 Jennifer Jaufmann; Melanie Carevic; Leyla Tümen; Derya Eliacik; Fee Schmitt; Dominik Hartl; Sandra Beer‐Hammer
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Multiomic analysis identifies natural intrapatient temporal variability and changes in response to systemic corticosteroid therapy in chronic rhinosinusitis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-21 Michael Hoggard; Bincy Jacob; David Wheeler; Melissa Zoing; Kevin Chang; Kristi Biswas; Martin Middleditch; Richard G. Douglas; Michael W. Taylor
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Animal models of rheumatoid arthritis‐associated interstitial lung disease Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-20 Li Xiong; Liang Xiong; Hong Ye; Wan‐Li Ma
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Allergy protection at farms—just a myth? Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-17 Matthias Wjst
Allergy on farms has a long history. “Hayfever,” one of the main allergic outcomes, has an origin in the farming community while also asthma is increased in farmers due to exposure to grain dust, animal dander and various chemicals,1, 2 Nevertheless Blackley3 noted already in 1873 that “these statistics of the occupations of hay‐fever patients bring out prominently the very curious circumstance that
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Data mining combined with experiments to validate CEP55 as a prognostic biomarker in colorectal cancer Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-15 Kang Lin; Xiaojian Zhu; Chen Luo; Fanqin Bu; Jinfeng Zhu; Zhengming Zhu
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Five immune‐gene‐signatures participate in the development and pathogenesis of Kawasaki disease Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-14 Han Nie; Shizhi Wang; Quanli Wu; Danni Xue; Weimin Zhou
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The characteristics of intestinal flora of IBS-D with different syndromes. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-17 Guanqun Chao,Shuo Zhang
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Differential susceptibility between skin and vaginal mucosa in sensitization phase of allergic contact dermatitis in mice. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-11 Taku Nishijo,Kanako Nakayama,Masaaki Miyazawa,Yasutaka Kuroda,Hitoshi Sakaguchi
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A novel risk score to predict cardiovascular complications in patients with coronavirus disease 2019 (COVID-19): A retrospective, multicenter, observational study. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-24 Dong Huang,Huan Yang,He Yu,Ting Wang,Rong Yao,Zongan Liang
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Impact of chronic endometritis on endometrial receptivity analysis results and pregnancy outcomes. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-23 Keiji Kuroda,Takashi Horikawa,Azusa Moriyama,Kazuki Nakao,Hiroyasu Juen,Satoru Takamizawa,Yuko Ojiro,Koji Nakagawa,Rikikazu Sugiyama
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Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-04 Yukihisa Inoue; Tsukasa Okamoto; Takayuki Honda; Yoshihisa Nukui; Takumi Akashi; Tamiko Takemura; Minoru Tozuka; Yasunari Miyazaki
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Stress‐induced premature senescence activated by the SENEX gene mediates apoptosis resistance of diffuse large B‐cell lymphoma via promoting immunosuppressive cells and cytokines Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-04 Jiyu Wang; Qianshan Tao; Ying Pan; Zhixiang Wanyan; Fengfeng Zhu; Xuanxuan Xu; Huiping Wang; Liuying Yi; Mei Zhou; Zhimin Zhai
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Association between HLA gene polymorphisms and mortality of COVID‐19: An in silico analysis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-13 Yusuke Tomita; Tokunori Ikeda; Ryo Sato; Takuro Sakagami
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MICA polymorphisms associated with antithyroid drug‐induced agranulocytosis in the Chinese Han population Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-05 Xiaojuan Gong; Pu Chen; Pan Ma; Jiayang Gao; Jingsi Yang; Hui Guo; Chunxia Yan; Bao Zhang; Yayi He
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Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-20 Marielena Jakobi; Alexander Kiefer; Hooman Mirzakhani; Manfred Rauh; Theodor Zimmermann; Paraskevi Xepapadaki; Barbara Stanic; Mubeccel Akdis; Nikolaos G. Papadopoulos; Benjamin A. Raby; Scott T. Weiss; Susetta Finotto
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A signature of 18 immune‐related gene pairs to predict the prognosis of pancreatic cancer patients Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-31 Fanqin Bu; Han Nie; Xiaojian Zhu; Ting Wu; Kang Lin; Jiefeng Zhao; Jun Huang
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Low dose IL‐2 suppress osteoclastogenesis in collagen‐induced arthritis via JNK dependent pathway Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-24 Han Sun; Yong Zhao; Kun Wang; Li Zhu; Jian Dong; Jie Zhao; Yimin Wang; Huan Li; Xiaoliang Sun; Yunjie Lu
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SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG2 antibodies against pneumococcal vaccine Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-24 Jennifer Jaufmann; Leyla Tümen; Fee Schmitt; Daniel Schäll; Max von Holleben; Sandra Beer‐Hammer
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Transcriptomic analysis reveals novel mechanisms of SARS‐CoV‐2 infection in human lung cells Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-30 Shaomin Yang; Songbin Wu; Zhijian Yu; Jiabin Huang; Xia Zhong; Xiaodong Liu; Hua Zhu; Lizu Xiao; Qiwen Deng; Wuping Sun
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Cesarean section and risk of allergies in Ecuadorian children: A cross‐sectional study Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-30 Amélie Gorris; Gabriela Bustamante; Katharina A. Mayer; Tamar Kinaciyan; Gerhard J. Zlabinger
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Characterization and protective efficacy of a sptP mutant of Salmonella Paratyphi A Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-01 Pengtao Pan; Fanyu Zou; Chuanshan He; Qunli He; Junlei Yin
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Harnessing noncoding RNA‐based macrophage polarization: Emerging therapeutic opportunities for fibrosis Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-20 Dexi Zhou; Yilai Wu; Sheng Wang; Jun Li; Jiajie Luan
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Macrophages in the pancreas: Villains by circumstances, not necessarily by actions. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-03 Andrea F Cruz,Rokhsareh Rohban,Farzad Esni
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What has single‐cell RNA sequencing revealed about microglial neuroimmunology? Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-21 Norwin Kubick; Patrick C. Henckell Flournoy; Pavel Klimovich; Gina Manda; Michel‐Edwar Mickael
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The impact of COVID‐19 control measures on the morbidity of varicella, herpes zoster, rubella and measles in Guangzhou, China Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-07 Di Wu; Qun Liu; Tiantian Wu; Dedong Wang; Jianyun Lu
The Coronavirus Disease 2019 (COVID‐19) pandemic have now becoming a worldwide catastrophe, as of September 9, 2020, the conformed COVID‐19 cases are 27,486,960, and 894,983 deaths are reported.1 Varicella (chickenpox), rubella and measles are also infectious diseases caused by the respiratory virus. We have noticed that the reported varicella cases, rubella cases, and measles cases in Guangzhou City
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False‐positive test results in diagnosing allergy to glatiramer acetate: Case report and a systematic literature review Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-10-05 Stefani Röseler; Friederike Leufgens; Hans F. Merk; Jens M. Baron; Silke Moll‐Slodowy; Gerda Wurpts; Galina Balakirski
Glatiramer acetate (GA; trade name: Copaxone®) is a mixture of synthetic polypeptides that is used for the immunomodulatory treatment of relapsing‐remitting multiple sclerosis (RRMS).1 While some mechanisms of action of GA are still not completely understood, it has been shown to bind to major histocompatibility complex molecules and to induce an in vivo change of the cytokine secretion pattern of
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MicroRNA‐378a‐3p contributes to ovarian cancer progression through downregulating PDIA4 Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-07 Yao Chanjiao; Chen Chunyan; Qiu Xiaoxin; Han Youjian
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Secreted TRAIL gene‐modified adipose‐derived stem cells exhibited potent tumor‐suppressive effect in hepatocellular carcinoma cells Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-06 Zhuo Liu; Shaojie Li; Tiexiang Ma; Jian Zeng; Xin Zhou; Huanyu Li; Min Tang; Xiang Liu; Feng Li; Bin Jiang; Ming Zhao; Ying Chen
Considering the potential of adipose‐derived stem cells (ADSCs) migrating towards cancer cells, this study was performed to explore the function of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) modified ADSCs on the development and progression of hepatocellular carcinoma (HCC).
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Plasma cytomegalovirus DNA load predicts outcomes in liver transplant recipients Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-03 Hao‐Chien Hung; Po‐Jung Hsu; Jin‐Chiao Lee; Yu‐Chao Wang; Chih‐Hsien Cheng; Tsung‐Han Wu; Ting‐Jung Wu; Hong‐Shiue Chou; Kun‐Ming Chan; Wei‐Chen Lee; Chen‐Fang Lee
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The performance of the alarmin HMGB1 in pediatric diseases: From lab to clinic Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-11-02 Bo Li; Xin Peng; He Li; Fei Chen; Yuxia Chen; Yingqian Zhang; Kai Le
High‐mobility group box protein 1 (HMGB1) is a ubiquitously expressed nonhistone nuclear protein that has multiple functions related to posttranslational modifications and cellular localization. In the nucleus, HMGB1 binds to DNA, regulating transcription and determining chromosomal architecture. When released into the extracellular space, HMGB1 activates innate immunity and mediates a wide range of
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Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor-beta expression in chronic rhinosinusitis with nasal polyps. Immun. Inflamm. Dis. (IF 2.5) Pub Date : 2020-09-01 Shui-Bin Wang,Shi-Ming Chen,Ke-Sheng Zhu,Bin Zhou,Long Chen,Xiao-Yan Zou