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Evaluation of the relationship of treatment and vaccination with prognosis in patients with a diagnosis of COVID-19 Inflammopharmacology (IF 5.8) Pub Date : 2024-03-16 Seyma Oncu, Derya Korkmaz
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Environmental enrichment reverses proulcerogenic action of social isolation on the gastric mucosa and positively influences pain sensitivity and work capacity Inflammopharmacology (IF 5.8) Pub Date : 2024-03-16 Ludmila P. Filaretova, Olga P. Komkova, Olga Yu. Morozova, Polina V. Punina, Natalia I. Yarushkina
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Resveratrol ameliorates DSS-induced ulcerative colitis by acting on mouse gut microbiota Inflammopharmacology (IF 5.8) Pub Date : 2024-03-16 Bing Yu, Ying Wang, Zekai Tan, Zhengyi Hong, Lewen Yao, Shiyuan Huang, Zexi Li, Lanyue Zhang, Hui Li
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Intraarticular monomethyl fumarate as a perspective therapy for osteoarthritis by macrophage polarization Inflammopharmacology (IF 5.8) Pub Date : 2024-03-13 Douglas Menezes de Souza, Kauê Franco Malange, Catarine Massucato Nishijima, Bruno Henrique de Melo Lima, Vinicius Cooper Capetini, Alexandre L. R. de Oliveira, Gabriel Forato Anhê, Claudia Herrera Tambeli, Carlos Amilcar Parada
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Antinociceptive and anti-inflammatory activity of extracts and α-pyrones isolated from Cantinoa stricta Inflammopharmacology (IF 5.8) Pub Date : 2024-03-11 Felipe Lukacievicz Barbosa, Carlos Augusto Ehrenfried, Débora Rasec Radulski, Cristhian Santos Oliveira, Maria Élida Alves Stefanello, Aleksander Roberto Zampronio
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Celecoxib attenuates hindlimb unloading-induced muscle atrophy via suppressing inflammation, oxidative stress and ER stress by inhibiting STAT3 Inflammopharmacology (IF 5.8) Pub Date : 2024-03-07 Yanan Ji, Junfei Lin, Ruiqi Liu, Kexin Wang, Mengyuan Chang, Zihui Gao, Boya Liu, Yuntian Shen, Jianwei Zhu, Xinlei Yao, Lei Qi, Hualin Sun
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Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion Inflammopharmacology (IF 5.8) Pub Date : 2024-03-07 Samun Nessa, S. Lavanya, Rajesh K. Routray, Akash Chaurasiya, Onkar P. Kulkarni, A. Sajeli Begum
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3-Acetyl coumarin alleviate neuroinflammatory responses and oxidative stress in aluminum chloride-induced Alzheimer’s disease rat model Inflammopharmacology (IF 5.8) Pub Date : 2024-03-06
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs mental ability and interrupts cognitive function. Heavy metal exposure like aluminum chloride is associated with neurotoxicity linked to neuro-inflammation, oxidative stress, accumulation of amyloid plaques, phosphorylation of tau proteins associated with AD like symptoms. The objective of the present investigation was to
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Sinomenine protects against atherosclerosis in apolipoprotein E-knockout mice by inhibiting of inflammatory pathway Inflammopharmacology (IF 5.8) Pub Date : 2024-03-02 Zhao Gao, Chao Yang, Guangwei Zeng, Ming Lin, Wei Li, Mengna Sun, Yantao Zhang, Beibei Fan, Yogesh Kumar, Kun Yan
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Pterostilbene: a potential therapeutic agent for fibrotic diseases Inflammopharmacology (IF 5.8) Pub Date : 2024-03-01 Wenhong Wang, Ke Li, Dandan Bai, Jiabin Wu, Weihua Xiao
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Anti-inflammatory and anti-arthritic potential of Coagulansin-A: in vitro and in vivo studies Inflammopharmacology (IF 5.8) Pub Date : 2024-02-27 Sadaf Naz, Muhammad Usama Mazhar, Umakant Yadav, Hamdy Abouzeid Ali, Fadi Khasawneh, Ihsan-ul-Haq, Muhammad Khalid Tipu, Lin Zhu
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Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis Inflammopharmacology (IF 5.8) Pub Date : 2024-02-26 Chenyu Zhao, Yunyuan Yu, Guangrong Yin, Chao Xu, Jiahao Wang, Liangliang Wang, Gongyin Zhao, Su Ni, Haoxing Zhang, Baojun Zhou, Yuji Wang
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Glabridin reduces neuroinflammation by modulating inflammatory signals in LPS-induced in vitro and in vivo models Inflammopharmacology (IF 5.8) Pub Date : 2024-02-19 Jiyu Weng, Ying Wang, Zekai Tan, Yanghe Yuan, Shiyuan Huang, Zexi Li, Yiming Li, Lanyue Zhang, Zhiyun Du
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The effects of silymarin consumption on inflammation and oxidative stress in adults: a systematic review and meta-analysis Inflammopharmacology (IF 5.8) Pub Date : 2024-02-19 Hossein Bahari, Mostafa Shahraki Jazinaki, Mohammad Rashidmayvan, Shaghayegh Taheri, Mohammad Reza Amini, Mahsa Malekahmadi
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Ameliorative effects of Atriplex crassifolia (C.A.Mey) on pain and inflammation through modulation of inflammatory biomarkers and GC–MS-based metabolite profiling Inflammopharmacology (IF 5.8) Pub Date : 2024-02-17 Sarah Rehman, Saiqa Ishtiaq, Muhammad Khalil-Ur-Rehman, Sairah Hafeez Kamran
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Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study Inflammopharmacology (IF 5.8) Pub Date : 2024-02-16 Zhaozhou Ren, Long Zhou
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Flavipin from fungi as a potential inhibitor of rheumatoid arthritis signaling molecules Inflammopharmacology (IF 5.8) Pub Date : 2024-02-13 Emad A. Ahmed, Abdulaah M. Alzahrani, Salah A. Abdelsalam, Hairul-Islam M. Ibrahim
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Role of corticosteroids in the treatment of critically ill sepsis patients: a meta-analysis review Inflammopharmacology (IF 5.8) Pub Date : 2024-02-12 Yutong Song, Jing Hao, Yanhua Liu
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Isolation, invitro, invivo anti-inflammatory, analgesic and antioxidant potential of Habenaria plantegania Lindl Inflammopharmacology (IF 5.8) Pub Date : 2024-02-09 Osama M. Alshehri, Madeeha Shabnam, Saeed Ahmed Asiri, Mater H. Mahnashi, Abdul Sadiq, Muhammad Saeed Jan
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A systematic review of interleukin-31 inhibitors in the treatment of prurigo nodularis Inflammopharmacology (IF 5.8) Pub Date : 2024-02-08 Mohammad Ali Nilforoushzadeh, Nazila Heidari, Yekta Ghane, Amirhossein Heidari, Arman Hajikarim-Hamedani, SeyedAyin Hosseini, Fariba Jaffary, Minou Najar Nobari, Pegah Tavakolzadeh, Niloufar Najar Nobari
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Evaluation of the biological efficiency of Terminalia chebula fruit extract against neurochemical changes induced in brain of diabetic rats: an epigenetic study Inflammopharmacology (IF 5.8) Pub Date : 2024-02-08
Abstract Diabetes mellitus (DM) is a chronic and progressive metabolic disorder that can stimulate neuroinflammation and increase oxidative stress in the brain. Therefore, the present study was aimed to assess the efficacy of ethanolic Terminalia chebula extract against the neurochemical and histopathological changes induced in the brains of diabetic rats. The study clarified the reduction in oxidative
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The effects of probiotic supplements on oxidative stress and inflammation in subjects with mild and moderate Alzheimer’s disease: a randomized, double-blind, placebo-controlled study Inflammopharmacology (IF 5.8) Pub Date : 2024-02-06 Camellia Akhgarjand, Zahra Vahabi, Sakineh Shab-Bidar, Aliarash Anoushirvani, Kurosh Djafarian
Through modulating effects on the gut-brain axis, probiotics are an effective adjuvant treatment for Alzheimer’s disease (AD), one of our century’s most important medical care challenges (Agahi et al. Front Neurol 9:662, 2018). This trial aimed to examine the effects of two different single-strain probiotics on oxidative stress and inflammation in patients with mild and moderate AD. This was a 12-week
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Phytochemical analysis and immunomodulatory activities in vitro and in vivo of Aframomum melegueta K Schum seed extracts Inflammopharmacology (IF 5.8) Pub Date : 2024-02-06 Mounia Latif, Ismail Elkoraichi, Othman El Faqer, Hicham Wahnou, El Mostafa Mtairag, Mounia Oudghiri, Samira Rais
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Leaf extracts of eight selected southern African medicinal plants modulate pro-inflammatory cytokine secretion in LPS-stimulated RAW 264.7 macrophages Inflammopharmacology (IF 5.8) Pub Date : 2024-02-04 Gugulethu P. Khumalo, Wendy Loa-Kum-Cheung, Ben-Erik Van Wyk, Yunjiang Feng, Ian E. Cock
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Neuroprotective mechanism of trans,trans-Farnesol in an ICV-STZ-induced rat model of Alzheimer’s pathology Inflammopharmacology (IF 5.8) Pub Date : 2024-02-03 Monika Kadian, Neetu Saini, Alka Khera, Anil Kumar
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Quercetin attenuates Pseudomonas aeruginosa-induced acute lung inflammation by inhibiting PI3K/AKT/NF-κB signaling pathway Inflammopharmacology (IF 5.8) Pub Date : 2024-02-03 Xiaolei Jia, Mengdi Gu, Jiangqin Dai, Jue Wang, Yingying Zhang, Zheng Pang
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Observational analysis of the immunogenicity and safety of various types of spinal muscular atrophy vaccines Inflammopharmacology (IF 5.8) Pub Date : 2024-02-03
Abstract Background This study aimed to evaluate the immunogenicity and safety of different types of poliovirus vaccines. Methods A randomized, blinded, single-center, parallel-controlled design was employed, and 360 infants aged ≥ 2 months were selected as study subjects. They were randomly assigned to bOPV group (oral Sabin vaccine) and sIPV group (Sabin strain inactivated polio vaccine), with 180
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Phytochemical profiling, antioxidant, cytotoxic, and anti-inflammatory activities of Plectranthus rugosus extract and fractions: in vitro, in vivo, and in silico approaches Inflammopharmacology (IF 5.8) Pub Date : 2024-02-03 Reyaz Hassan Mir, Roohi Mohi-ud-din, Lamya Ahmed Al-Keridis, Bilal Ahmad, Nawaf Alshammari, Mitesh Patel, Mohd Adnan, Mubashir Hussain Masoodi
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D-limonene inhibits peritoneal adhesion formation in rats via anti-inflammatory, anti-angiogenic, and antioxidative effects Inflammopharmacology (IF 5.8) Pub Date : 2024-02-03 Ali Razazi, Ali Kakanezhadi, Abbas Raisi, Behnam Pedram, Omid Dezfoulian, Farshid Davoodi
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Neuroprotective potential of Erigeron bonariensis ethanolic extract against ovariectomized/D-galactose-induced memory impairments in female rats in relation to its metabolite fingerprint as revealed using UPLC/MS Inflammopharmacology (IF 5.8) Pub Date : 2024-01-31 Weam W. Ibrahim, Rabab H. Sayed, Mohamed F. Abdelhameed, Enayat A. Omara, Mahmoud I. Nassar, Noha F. Abdelkader, Mohamed A. Farag, Abdelsamed I. Elshamy, Sherif M. Afifi
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Repurposing metformin to manage idiopathic or long COVID Tinnitus: self-report adopting a pathophysiological and pharmacological approach Inflammopharmacology (IF 5.8) Pub Date : 2024-01-31 Mina T. Kelleni
Chronic tinnitus is a common neurological disorder that affects millions of patients globally with no available successful pharmacotherapy. It can be extremely bothersome to some patients to the extent that it occasionally qualifies as a disability that can hinder them from leading a normal life. In this short communication, the author discusses how he suffered from idiopathic tinnitus and how he managed
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Aquaporins (AQPs) as a marker in the physiology of inflammation and its interaction studies with garcinol Inflammopharmacology (IF 5.8) Pub Date : 2024-01-24
Abstract Aquaporins like AQP1, AQP3, and AQP4 are known to be involved in the pathophysiology of inflammation based on earlier reports. This study aimed to evaluate the involvement of Aquaporins as a potential target of inflammation. The study also investigates the efficacy of methanolic extract of Garcinia (GME) and its potent phytocompound (garcinol) against the Aquaporins involved in inflammation
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The effects of melatonin supplementation on neurobehavioral outcomes and clinical severity in rodent models of multiple sclerosis; a systematic review and meta-analysis Inflammopharmacology (IF 5.8) Pub Date : 2024-01-22 Hadis Razmaray, Ehsan Nasiri, Pouya Vakilipour, Soroush Morsali, Afshin Moradi, Asal Ebrahimian, Sahel Rashidi, Reza Mosaddeghi-Heris, Saeed Sadigh-Eteghad, Amirreza Naseri
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Correction to: Chrysophanol exerts a protective effect against Aβ25‑35‑induced Alzheimer’s disease model through regulating the ROS/TXNIP/NLRP3 pathway Inflammopharmacology (IF 5.8) Pub Date : 2024-01-18 Meng Zhang, Zhi‑xian Ding, Wei Huang, Jing Luo, Shu Ye, Sheng‑lin Hu, Peng Zhou, Biao Cai
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Correction: Curcumin potentiates the anti-inflammatory effects of Tehranolide by modulating the STAT3/NF-κB signaling pathway in breast and ovarian cancer cell lines Inflammopharmacology (IF 5.8) Pub Date : 2024-01-18 Havva Afshari, Shokoofe Noori, Afshin Zarghi
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Baricitinib relieves DSS-induced ulcerative colitis in mice by suppressing the NF-κB and JAK2/STAT3 signalling pathways Inflammopharmacology (IF 5.8) Pub Date : 2024-01-16
Abstract Ulcerative colitis (UC) is a relapsing inflammatory disease with a unique aetiology. The treatment of UC is challenging, and the current clinical therapeutics for colitis have limited efficacy. Thus, finding new and effective treatment options remains urgent. Baricitinib, an inhibitor of Janus kinase (JAK), has been clinically used to treat rheumatoid arthritis (RA). However, its potential
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Neuropeptide W facilitates chronic gastric ulcer healing by the regulation of cyclooxygenase and NF-κB signaling pathways Inflammopharmacology (IF 5.8) Pub Date : 2024-01-16
Abstract Aims Putative beneficial effects of neuropeptide W (NPW) in the early phase of gastric ulcer healing process and the involvement of cyclooxygenase (COX) enzymes were investigated in an acetic acid-induced gastric ulcer model. Main methods In anesthetized male Sprague–Dawley rats, acetic acid was applied surgically on the serosa and then a COX-inhibitor (COX-2-selective NS-398, COX-1-selective
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The therapeutic effect of Loranthus parasiticus lignan derivatives on collagen-induced arthritis in rats through the SHBG/NFκB pathway Inflammopharmacology (IF 5.8) Pub Date : 2024-01-16 Jiali Bai, Cong Zhang, Yulin Liu, Nanzhen Kuang, Liangquan Xu, Zhengang Xu, Haiwei Wang, Renping Liu
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Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies Inflammopharmacology (IF 5.8) Pub Date : 2024-01-11 Jagat Pal Yadav, Ankit Kumar Singh, Maria Grishina, Prateek Pathak, Amita Verma, Vikas Kumar, Pradeep Kumar, Dinesh Kumar Patel
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Unraveling the potential of vitamins C and D as adjuvants in depression treatment with escitalopram in an LPS animal model Inflammopharmacology (IF 5.8) Pub Date : 2024-01-05 Omar Gammoh, Rand T. Akasheh, Esam Qnais, Sara Al-Taber, Rabaa Y. Athamneh, Amin A. Hafiz, Abdelrahim Alqudah, Alaa A. A. Aljabali, Murtaza M. Tambuwala
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Icariin ameliorates the cuprizone-induced demyelination associated with antioxidation and anti-inflammation Inflammopharmacology (IF 5.8) Pub Date : 2024-01-04 Li-Juan Song, Qing-Xian Han, Zhi-Bin Ding, Kexin Liu, Xiao-Xu Zhang, Min-Fang Guo, Dong Ma, Qing Wang, Bao-Guo Xiao, Cun-Gen Ma
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The effect of acarbose on inflammatory cytokines and adipokines in adults: a systematic review and meta-analysis of randomized clinical trials Inflammopharmacology (IF 5.8) Pub Date : 2024-01-03 Ali Mohammadian, Sahand Tehrani Fateh, Mahlagha Nikbaf-Shandiz, Fatemeh Gholami, Niloufar Rasaei, Hossein Bahari, Samira Rastgoo, Reza Bagheri, Farideh Shiraseb, Omid Asbaghi
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Hexahydrocurcumin attenuated demyelination and improved cognitive impairment in chronic cerebral hypoperfusion rats Inflammopharmacology (IF 5.8) Pub Date : 2023-12-28
Abstract Age-related white matter lesions (WML) frequently present vascular problems by decreasing cerebral blood supply, resulting in the condition known as chronic cerebral hypoperfusion (CCH). This study aimed to investigate the effect of hexahydrocurcumin (HHC) on the processes of demyelination and remyelination induced by the model of the Bilateral Common Carotid Artery Occlusion (BCCAO) for 29 days
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NLRs and inflammasome signaling in opioid-induced hyperalgesia and tolerance Inflammopharmacology (IF 5.8) Pub Date : 2023-12-28 Nasrin Zare, Fateme Sharafeddin, AmirMahdi Montazerolghaem, Nastaran Moradiannezhad, Mohammaderfan Araghizadeh
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Effect of use of NSAIDs or steroids during the acute phase of pain on the incidence of chronic pain: a systematic review and meta-analysis of randomised trials Inflammopharmacology (IF 5.8) Pub Date : 2023-12-28 Luyao Huo, Gang Liu, Bowen Deng, Lin Xu, Yanjun Mo, Shengyuan Jiang, Jingwei Tao, Huizhong Bai, Li Wang, Xiaoxiao Yang, Jizhou Yang, Xiaohong Mu
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Pseudolaric acid B exerts an antifungal effect and targets SIRT1 to ameliorate inflammation by regulating Nrf2/NF-κB pathways in fungal keratitis Inflammopharmacology (IF 5.8) Pub Date : 2023-12-27 Shuyi Liu, Tao Qin, Fengkai Zou, He Dong, Liang Yu, Hai Wang, Lijun Zhang
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Rheumatoid arthritis is a protective factor against Alzheimer’s disease: a bidirectional two-sample Mendelian randomization study Inflammopharmacology (IF 5.8) Pub Date : 2023-12-27
Abstract Background Epidemiological evidence suggests that there is an association between rheumatoid arthritis (RA) and Alzheimer’s disease (AD). However, the causal relationship between RA and AD remains unclear. Therefore, this study aimed to investigate the causal relationship between RA and AD. Methods Using publicly available genome-wide association study datasets, bidirectional two-sample Mendelian
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Mesenchymal stem cell therapy for COVID-19 infection Inflammopharmacology (IF 5.8) Pub Date : 2023-12-20 Seyyed Mohammad Matin Alavi-Dana, Yazdan Gholami, Mohammadreza Meghdadi, Mohammad Saleh Fadaei, Vahid Reza Askari
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Rapamycin can alleviate the submandibular gland pathology of Sjögren's syndrome by limiting the activation of cGAS–STING signaling pathway Inflammopharmacology (IF 5.8) Pub Date : 2023-12-19 Wen Zhu, Yabei Wang, Yin Guan, Yun Lu, Yehui Li, Lixia sun, Yue Wang
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Neuroprotective effect of curcumin against experimental autoimmune encephalomyelitis-induced cognitive and physical impairments in mice: an insight into the role of the AMPK/SIRT1 pathway Inflammopharmacology (IF 5.8) Pub Date : 2023-12-19 Mohamed A. Sadek, Mostafa A. Rabie, Nesrine S. El Sayed, Helmy M. Sayed, Esraa A. Kandil
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Malvidin alleviates LPS-induced septic intestinal injury through the nuclear factor erythroid 2-related factor 2/reactive oxygen species/NLRP3 inflammasome pathway Inflammopharmacology (IF 5.8) Pub Date : 2023-12-15
Abstract Emerging evidence suggests that the gastrointestinal tract plays a crucial role in the pathophysiology of sepsis, a leading cause of mortality among patients admitted to the intensive care unit (ICU). Malvidin, belonging to the flavonoid family of compounds, exhibits a range of capabilities including anti-inflammatory and antioxidant properties. Studies have demonstrated that Malvidin exhibits
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Intravenous immunoglobulin for treatment of hospitalized COVID-19 patients: an evidence mapping and meta-analysis Inflammopharmacology (IF 5.8) Pub Date : 2023-12-14 Mei-xuan Li, Yan-fei Li, Xin Xing, Jun-qiang Niu, Liang Yao, Meng-ying Lu, Ke Guo, Mi-na Ma, Xiao-tian Wu, Ning Ma, Dan Li, Zi-jun Li, Ling Guan, Xiao-man Wang, Bei Pan, Wen-ru Shang, Jing Ji, Zhong-yang Song, Zhi-ming Zhang, Yong-feng Wang, Ke-hu Yang
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Inhibition of TLR4, NF-κB, and INOS pathways mediates ameliorative effect of syringic acid in experimental ulcerative colitis in rats Inflammopharmacology (IF 5.8) Pub Date : 2023-12-14 Maryam Ghasemi-Dehnoo, Hossein Amini-Khoei, Zahra Lorigooini, Maryam AnjomShoa, Elham Bijad, Mahmoud Rafieian-Kopaei
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Targeting cardiovascular risk factors with eugenol: an anti-inflammatory perspective Inflammopharmacology (IF 5.8) Pub Date : 2023-12-12 Sushma Devi, Samrat Chauhan, Ashi Mannan, Thakur Gurjeet Singh
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Natural agents as wound-healing promoters Inflammopharmacology (IF 5.8) Pub Date : 2023-12-07 Negin Akhtari, Mahnaz Ahmadi, Yasaman Kiani Doust Vaghe, Elham Asadian, Sahar Behzad, Hossein Vatanpour, Fatemeh Ghorbani-Bidkorpeh
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Assessment of antiarthritic potential of Asparagus dumosus using formaldehyde and CFA-induced arthritic models in rats via modulation of oxidative stress biomarkers and mRNA expression of IL-1b, IL-6, RANKL, OPG, TNF-α and COX-2 Inflammopharmacology (IF 5.8) Pub Date : 2023-12-07 Nimra Nazar, Malik Hassan Mehmood, Rida Siddique, Muhammad Naeem Faisal
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Using aspirin to prevent and treat cancer Inflammopharmacology (IF 5.8) Pub Date : 2023-12-08 Lenard M. Lichtenberger
This review will discuss evidence that aspirin possesses anticancer activity. Long-term observational retrospective studies on nurses and health professionals demonstrated that regular aspirin users had a significantly lower incidence of colorectal cancer (RCT). Prospective studies on patients with a high risk of developing colorectal polyps/cancer confirmed that aspirin use significantly lowered colorectal
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Empagliflozin repurposing in Parkinson’s disease; modulation of oxidative stress, neuroinflammation, AMPK/SIRT-1/PGC-1α, and wnt/β-catenin pathways Inflammopharmacology (IF 5.8) Pub Date : 2023-12-01 Noha Nabil Mohammed, Mariane G. Tadros, Mina Y. George
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Resveratrol protects against Schistosoma mansoni-induced liver fibrosis by targeting the Sirt-1/NF-κB axis Inflammopharmacology (IF 5.8) Pub Date : 2023-12-02 Dalia Kamal Mostafa, Maha M. Eissa, Doaa A. Ghareeb, Shaymaa Abdulmalek, Wafaa A. Hewedy
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Therapeutic potential and possible mechanisms of ginseng for depression associated with COVID-19 Inflammopharmacology (IF 5.8) Pub Date : 2023-11-27 Fangyi Zhao, Kai Zhang, Hongyu Chen, Tianqi Zhang, Jiayu Zhao, Qianyu Lv, Qin Yu, Mengyu Ruan, Ranji Cui, Bingjin Li